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Center for Computational Systems Medicine
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Fusion Gene Summary

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Fusion Gene ORF analysis

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Fusion Genomic Features

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Fusion Protein Features

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Fusion Gene Sequence

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Fusion Gene PPI analysis

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Related Drugs

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Related Diseases

Fusion gene:MTFR1L-BROX (FusionGDB2 ID:55654)

Fusion Gene Summary for MTFR1L-BROX

check button Fusion gene summary
Fusion gene informationFusion gene name: MTFR1L-BROX
Fusion gene ID: 55654
HgeneTgene
Gene symbol

MTFR1L

BROX

Gene ID

56181

148362

Gene namemitochondrial fission regulator 1 likeBRO1 domain and CAAX motif containing
SynonymsFAM54B|HYST1888|MST116|MSTP116C1orf58
Cytomap

1p36.11

1q41

Type of geneprotein-codingprotein-coding
Descriptionmitochondrial fission regulator 1-likefamily with sequence similarity 54 member Bprotein FAM54BBRO1 domain-containing protein BROX
Modification date2020031320200313
UniProtAcc

Q9H019

Q5VW32

Ensembl transtripts involved in fusion geneENST00000466284, ENST00000469815, 
ENST00000474295, ENST00000526894, 
ENST00000374300, ENST00000374301, 
ENST00000374303, ENST00000374307, 
ENST00000524618, 		ENST00000340934, 
ENST00000537020, ENST00000539697, 
ENST00000496267, 
Fusion gene scores* DoF score4 X 4 X 1=164 X 4 X 2=32
# samples 44
** MAII scorelog2(4/16*10)=1.32192809488736
effective Gene in Pan-Cancer Fusion Genes (eGinPCFGs).
DoF>8 and MAII>0		log2(4/32*10)=0.321928094887362
effective Gene in Pan-Cancer Fusion Genes (eGinPCFGs).
DoF>8 and MAII>0
Context

PubMed: MTFR1L [Title/Abstract] AND BROX [Title/Abstract] AND fusion [Title/Abstract]

Most frequent breakpointMTFR1L(26156304)-BROX(222906016), # samples:1
Anticipated loss of major functional domain due to fusion event.
* DoF score (Degree of Frequency) = # partners X # break points X # cancer types
** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)

check button Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez
PartnerGeneGO IDGO termPubMed ID

check buttonFusion gene breakpoints across MTFR1L (5'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check buttonFusion gene breakpoints across BROX (3'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check button Fusion gene information from two resources (ChiTars 5.0 and ChimerDB 4.0)
* All genome coordinats were lifted-over on hg19.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
SourceDiseaseSampleHgeneHchrHbpHstrandTgeneTchrTbpTstrand
ChiTaRS5.0N/ABF089900MTFR1Lchr1

26156304

-BROXchr1

222906016

-


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Fusion Gene ORF analysis for MTFR1L-BROX

check button Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
ORFHenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrand
3UTR-3CDSENST00000466284ENST00000340934MTFR1Lchr1

26156304

-BROXchr1

222906016

-
3UTR-3CDSENST00000469815ENST00000340934MTFR1Lchr1

26156304

-BROXchr1

222906016

-
3UTR-3CDSENST00000474295ENST00000340934MTFR1Lchr1

26156304

-BROXchr1

222906016

-
3UTR-3CDSENST00000526894ENST00000340934MTFR1Lchr1

26156304

-BROXchr1

222906016

-
3UTR-3UTRENST00000466284ENST00000537020MTFR1Lchr1

26156304

-BROXchr1

222906016

-
3UTR-3UTRENST00000466284ENST00000539697MTFR1Lchr1

26156304

-BROXchr1

222906016

-
3UTR-3UTRENST00000469815ENST00000537020MTFR1Lchr1

26156304

-BROXchr1

222906016

-
3UTR-3UTRENST00000469815ENST00000539697MTFR1Lchr1

26156304

-BROXchr1

222906016

-
3UTR-3UTRENST00000474295ENST00000537020MTFR1Lchr1

26156304

-BROXchr1

222906016

-
3UTR-3UTRENST00000474295ENST00000539697MTFR1Lchr1

26156304

-BROXchr1

222906016

-
3UTR-3UTRENST00000526894ENST00000537020MTFR1Lchr1

26156304

-BROXchr1

222906016

-
3UTR-3UTRENST00000526894ENST00000539697MTFR1Lchr1

26156304

-BROXchr1

222906016

-
3UTR-intronENST00000466284ENST00000496267MTFR1Lchr1

26156304

-BROXchr1

222906016

-
3UTR-intronENST00000469815ENST00000496267MTFR1Lchr1

26156304

-BROXchr1

222906016

-
3UTR-intronENST00000474295ENST00000496267MTFR1Lchr1

26156304

-BROXchr1

222906016

-
3UTR-intronENST00000526894ENST00000496267MTFR1Lchr1

26156304

-BROXchr1

222906016

-
5CDS-3UTRENST00000374300ENST00000537020MTFR1Lchr1

26156304

-BROXchr1

222906016

-
5CDS-3UTRENST00000374300ENST00000539697MTFR1Lchr1

26156304

-BROXchr1

222906016

-
5CDS-3UTRENST00000374301ENST00000537020MTFR1Lchr1

26156304

-BROXchr1

222906016

-
5CDS-3UTRENST00000374301ENST00000539697MTFR1Lchr1

26156304

-BROXchr1

222906016

-
5CDS-3UTRENST00000374303ENST00000537020MTFR1Lchr1

26156304

-BROXchr1

222906016

-
5CDS-3UTRENST00000374303ENST00000539697MTFR1Lchr1

26156304

-BROXchr1

222906016

-
5CDS-3UTRENST00000374307ENST00000537020MTFR1Lchr1

26156304

-BROXchr1

222906016

-
5CDS-3UTRENST00000374307ENST00000539697MTFR1Lchr1

26156304

-BROXchr1

222906016

-
5CDS-3UTRENST00000524618ENST00000537020MTFR1Lchr1

26156304

-BROXchr1

222906016

-
5CDS-3UTRENST00000524618ENST00000539697MTFR1Lchr1

26156304

-BROXchr1

222906016

-
5CDS-intronENST00000374300ENST00000496267MTFR1Lchr1

26156304

-BROXchr1

222906016

-
5CDS-intronENST00000374301ENST00000496267MTFR1Lchr1

26156304

-BROXchr1

222906016

-
5CDS-intronENST00000374303ENST00000496267MTFR1Lchr1

26156304

-BROXchr1

222906016

-
5CDS-intronENST00000374307ENST00000496267MTFR1Lchr1

26156304

-BROXchr1

222906016

-
5CDS-intronENST00000524618ENST00000496267MTFR1Lchr1

26156304

-BROXchr1

222906016

-
In-frameENST00000374300ENST00000340934MTFR1Lchr1

26156304

-BROXchr1

222906016

-
In-frameENST00000374301ENST00000340934MTFR1Lchr1

26156304

-BROXchr1

222906016

-
In-frameENST00000374303ENST00000340934MTFR1Lchr1

26156304

-BROXchr1

222906016

-
In-frameENST00000374307ENST00000340934MTFR1Lchr1

26156304

-BROXchr1

222906016

-
In-frameENST00000524618ENST00000340934MTFR1Lchr1

26156304

-BROXchr1

222906016

-

check buttonORFfinder result based on the fusion transcript sequence of in-frame fusion genes.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandSeq length
(transcript)		BP loci
(transcript)		Predicted start
(transcript)		Predicted stop
(transcript)		Seq length
(amino acids)
ENST00000374303MTFR1Lchr126156304-ENST00000340934BROXchr1222906016-3200678165746193
ENST00000524618MTFR1Lchr126156304-ENST00000340934BROXchr1222906016-314362139689216
ENST00000374307MTFR1Lchr126156304-ENST00000340934BROXchr1222906016-310358168649193
ENST00000374301MTFR1Lchr126156304-ENST00000340934BROXchr1222906016-3298776263844193
ENST00000374300MTFR1Lchr126156304-ENST00000340934BROXchr1222906016-3252730217798193

check buttonDeepORF prediction of the coding potential based on the fusion transcript sequence of in-frame fusion genes. DeepORF is a coding potential classifier based on convolutional neural network by comparing the real Ribo-seq data. If the no-coding score < 0.5 and coding score > 0.5, then the in-frame fusion transcript is predicted as being likely translated.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandNo-coding scoreCoding score
ENST00000374303ENST00000340934MTFR1Lchr126156304-BROXchr1222906016-0.0365441440.96345586
ENST00000524618ENST00000340934MTFR1Lchr126156304-BROXchr1222906016-0.075756040.9242439
ENST00000374307ENST00000340934MTFR1Lchr126156304-BROXchr1222906016-0.036005580.9639944
ENST00000374301ENST00000340934MTFR1Lchr126156304-BROXchr1222906016-0.03451770.96548223
ENST00000374300ENST00000340934MTFR1Lchr126156304-BROXchr1222906016-0.0338215120.9661785

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Fusion Genomic Features for MTFR1L-BROX


check buttonFusionAI prediction of the potential fusion gene breakpoint based on the pre-mature RNA sequence context (+/- 5kb of individual partner genes, total 20kb length sequence). FusionAI is a fusion gene breakpoint classifier based on convolutional neural network by comparing the fusion positive and negative sequence context of ~ 20K fusion gene data. From here, we can have the relative potentency of the 20K genomic sequence how individual sequnce will be likely used as the gene fusion breakpoints.
HgeneHchrHbpHstrandTgeneTchrTbpTstrand1-pp (fusion gene breakpoint)

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions. We integrated a total of 44 different types of human genomic feature loci information across five big categories including virus integration sites, repeats, structural variants, chromatin states, and gene expression regulation. More details are in help page.
genomic feature

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions that are ovelapped with the top 1% feature importance score regions. More details are in help page.

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Fusion Protein Features for MTFR1L-BROX


check button Four levels of functional features of fusion genes
Go to FGviewer search page for the most frequent breakpoint (https://ccsmweb.uth.edu/FGviewer/chr1:26156304/chr1:222906016)
- FGviewer provides the online visualization of the retention search of the protein functional features across DNA, RNA, protein, and pathological levels.
- How to search
1. Put your fusion gene symbol.
2. Press the tab key until there will be shown the breakpoint information filled.
4. Go down and press 'Search' tab twice.
4. Go down to have the hyperlink of the search result.
5. Click the hyperlink.
6. See the FGviewer result for your fusion gene.
FGviewer

check buttonMain function of each fusion partner protein. (from UniProt)
HgeneTgene
MTFR1L

Q9H019

BROX

Q5VW32


check buttonRetention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at

download page


* Minus value of BPloci means that the break pointn is located before the CDS.
- In-frame and retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
TgeneBROXchr1:26156304chr1:222906016ENST0000034093401390_4080412.0DomainBRO1

- In-frame and not-retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note


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Fusion Gene Sequence for MTFR1L-BROX


check button For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. To have fusion amino acid sequence, we ran ORFfinder and chose the longest ORF among the all predicted ones.
>55654_55654_1_MTFR1L-BROX_MTFR1L_chr1_26156304_ENST00000374300_BROX_chr1_222906016_ENST00000340934_length(transcript)=3252nt_BP=730nt
CAGTTATCTAGTTCCTCTCGCGAGGACTCCGAGGGACAGGCAGGGTGCTGCGGAGCGCACAGGAAAGGACCTGACCCTGTCGCAGGGAAG
GAAGGTGATGCTTAAGCTGAGCTCTGAGGAATGATGAAGAATGAGCTCGGCGAAGGGGGTGCTGGTGTTTGATGCAGGGCTCAGAGATGG
CCTGATATGAAGGAGTCACGCCTCCCGCCTCCCGGAGCTGCCCAGTGGCTGCCTTGTCCTTCAAGTGCAGGAGCTGGTTCAAATGTCAGG
AATGGAAGCCACTGTGACCATCCCAATCTGGCAAAACAAGCCACATGGGGCTGCTCGAAGTGTAGTAAGAAGAATTGGGACCAACCTACC
CTTGAAGCCGTGTGCCCGGGCGTCCTTTGAGACCCTGCCCAACATCTCTGACCTGTGTTTGAGAGATGTGCCCCCAGTCCCTACCCTGGC
TGACATCGCCTGGATTGCTGCGGATGAAGAGGAGACATATGCCCGGGTCAGGAGTGATACGCGCCCCCTGAGGCACACCTGGAAACCCAG
CCCTCTGATTGTCATGCAGCGCAATGCCTCTGTTCCCAACCTGCGTGGGTCCGAGGAGAGGCTTCTGGCCCTGAAGAAGCCAGCTCTGCC
AGCCCTAAGCCGCACTACTGAGCTGCAGGACGAGCTGAGCCACTTGCGCAGCCAGATTGCAAAGATAGTGGCAGCTGATGCAGAAACAGA
GTCAAGATCTCATCAAACCTCAAAAGGACACTGGGTGCTACATCTCCTAAAATACAACTTGCACTTAGAATTTCTCTAGCAGTAAATAAG
ATAAACCACAGAATTTCAGTTCTTATTTCTCAAAATGATTTCTCTGAAGCTTGTAGAATAACTATTATATTCAGAGGGTTATCTGCCTTC
AGCTTACTTGTTCTTAATTTTTAATACAGCGGAGATGTTTCTTGCTTTGTTTTCAGACTCTCCTTTTTAATCAGGACAACATTTGAAAGA
TTTTATTGTGCCTCTAAAGGGTATATTTGGGGGTTGGGTCTTTTTGTTAAACTCTGGATAGTAATAAGTTTCAGGTCAGTATAGGCCCGA
ATCATGTGGTTTCAGGTATGTTTTTCTTTTTTCTTTTTCTTTTTTTTTTTTCTTTTTTTTTTTTTTTTTTTTTGAGGTGGAGTCTCCCTC
TGTTGCCCAGGCTGGAGTGCAGTGGCATGATCTCGGCTCACTGCAACCCTCCACCTCCTGAATTAAAGTGATTCTCCTGCCTCAGCCTCC
CGAGTAGCTGGGATTACAGGCACGCACCACTACACCCAGATAATTTTTGTATTTTTAGTAGAGACGTGATTTCACCATGTTGGCCAGGCT
GGTCTCGAACTCCTGACCTCAGCTGATCTGCCCGCCTTGGCCTCCCAAAGTGCTGGGATTACAGGCGTGATCCACTGCACCTGGCCTCAG
GTATGTTTTTCTATCTACACACAAAAAGTTTATTTTCCTTCCTCTTATTTGATATCAGAAGAATGACAGGAATCAGTTTTTAACAGAGAT
AGTTTTTCCGTTTCTCCATTGTGTTAATCAGAGCGCAGACTTACATTCTCAGTCATTTATCTTTTCTGGTGGAGAATAAAAAGTCACTTA
TAGTTAAAGATCAGAAAATTATCACACCAAATCCATTACATATGTTAGAATCAATAATTTACTCAAAAATCAGCTTTTATAGGTATGTTG
GCACCTTATCCAAGAACTTATCCCTGTTCCAGTACCCCTGTGCTTCATTCAGTATCAGTAACCCTGCAATGATTTTTACAAATATCTTTT
TCTAGTGGGTTTTTTACTTAGAGGAAAGAACTTTGTAATAGCTCTTAATGTTTATATATAAGAGAAGACAGAATGGAAAATGTTTTTTGA
AGTCAAATATTGCATGATGTAAAGAAAAAACTTTAAACTTAAATGAGTAGGTTGTCCTGAATTACACTGGTAACTCTCTACTTCTTTATT
AAAGAAGTTATAGTAAGATGCCTTTGTTACCTGATTTCAGTGTACATTGTTTTTATGTGGTTTTCTGATAATGTCCTGTCAGAATTGTAT
TGGTTTAGGCCAAAGGCCATAGCAAAAACATAGAGAACAAATATGATCTTAAAAATAGATTGTAACATTTTAAACAATTAGTTTAGTAAT
TTGGGAAATAGTGGATGCATAATACTTTAACAGAAGTCACACATCTGTAGGTTTATCTTTTGATTATTCTCCTGAGGCATTAGATAGTTT
TTCTATTATAAGTGACAGATTGACTCACTTAATATAAATAAGTAGCATACACTAAAAGCTTACTATGTGCCAGATACTGTGCTGGACACT
TACATAGATAAGCCATTGAATCCACACAGCAGCCCTGTAAGAAATAAGTAAAATCTGCATAAAGTGTTGAAATAGGAATATACATTTCAT
TATGAAAAATGAATAGATTATGCCTATCTGAATCAATATTGCATTCAAATAAGTGATTACTTAAATCATATATCATAGTTTACACTCCTT
AAAAAAAGGTACATAAATTCAGTGAGGTTTTTTTCTTAACATACAGAAGTACTAAATACTGCTTGCAGTATAATATTGATATTGGAAGCT
GCAGTTTCCAGAATAAGTGGAGTAATAACTAAACAGACATTTAATTTTATTTCAATATCTATGGAAAAAACACTTATTAAATCTCCCTGT
ATTTTATGTTGTCTTTATTACAGAATCACTTGTCTGTTTGTTGTGTGCCACTTACTGACAAAACTTTAAACAGTACTTGATGCCAGCTCT
CTACTCTGTGGCTGTGGGACCTGTTTCTTTTAGGTACTTGTGCTTATTAATCTACTTACTAAATTTTCACATTGACATTTTTGGGGATGA
TACTACCATATACGAAATGGAAAATGTAATATGCTCAGTGCTTCTGTAAAATGCAGCAATACTGGTATTACTTTACATCAGTAGGCATCT
TTGACATGAGCATATAAATATTTTGTTGACTCAGCAAAGGTGACACTTTGTGACTAAAGTATCCCATTATATATAATGTTTTTTGAAATG
TTGGAAATTTTGGGGAATTATCAAATGTATAGAAGTTGCATGAAGGTTATAGAGAGGTGTAACTGTTTGTTAACTATTACATGGATTTCA
TACTAGGCAGTGACAACTAACATGTTACTTCAACTAAAAGTGTATAATGGGTTGTCTTTTTATTTATGAAAATAAAAGTAATTTTACTTA

>55654_55654_1_MTFR1L-BROX_MTFR1L_chr1_26156304_ENST00000374300_BROX_chr1_222906016_ENST00000340934_length(amino acids)=193AA_BP=171
MPSGCLVLQVQELVQMSGMEATVTIPIWQNKPHGAARSVVRRIGTNLPLKPCARASFETLPNISDLCLRDVPPVPTLADIAWIAADEEET
YARVRSDTRPLRHTWKPSPLIVMQRNASVPNLRGSEERLLALKKPALPALSRTTELQDELSHLRSQIAKIVAADAETESRSHQTSKGHWV

--------------------------------------------------------------
>55654_55654_2_MTFR1L-BROX_MTFR1L_chr1_26156304_ENST00000374301_BROX_chr1_222906016_ENST00000340934_length(transcript)=3298nt_BP=776nt
GAGTCCCCGAAGGGTAGTTGCTCGTCGGAGTTCCCCAGCAAACAGTGACCAAGCCAGACCTCAGGCTTCTAGTTTCGGCTTCGCTGCTTG
ACGGGCCGGGCTGCCCCGCCGCGCATTCTGAGACCTGGCCGCGGCTCGGAGGCTTCCGCGCACTCGGGTCCGGGTCCTGTGGGTCCAAGG
GCCGCTGGGCAGGCGGCGAGCACTTGGCCGACCTTGGCCCAGATGGCCTGATATGAAGGAGTCACGCCTCCCGCCTCCCGGAGCTGCCCA
GTGGCTGCCTTGTCCTTCAAGTGCAGGAGCTGGTTCAAATGTCAGGAATGGAAGCCACTGTGACCATCCCAATCTGGCAAAACAAGCCAC
ATGGGGCTGCTCGAAGTGTAGTAAGAAGAATTGGGACCAACCTACCCTTGAAGCCGTGTGCCCGGGCGTCCTTTGAGACCCTGCCCAACA
TCTCTGACCTGTGTTTGAGAGATGTGCCCCCAGTCCCTACCCTGGCTGACATCGCCTGGATTGCTGCGGATGAAGAGGAGACATATGCCC
GGGTCAGGAGTGATACGCGCCCCCTGAGGCACACCTGGAAACCCAGCCCTCTGATTGTCATGCAGCGCAATGCCTCTGTTCCCAACCTGC
GTGGGTCCGAGGAGAGGCTTCTGGCCCTGAAGAAGCCAGCTCTGCCAGCCCTAAGCCGCACTACTGAGCTGCAGGACGAGCTGAGCCACT
TGCGCAGCCAGATTGCAAAGATAGTGGCAGCTGATGCAGAAACAGAGTCAAGATCTCATCAAACCTCAAAAGGACACTGGGTGCTACATC
TCCTAAAATACAACTTGCACTTAGAATTTCTCTAGCAGTAAATAAGATAAACCACAGAATTTCAGTTCTTATTTCTCAAAATGATTTCTC
TGAAGCTTGTAGAATAACTATTATATTCAGAGGGTTATCTGCCTTCAGCTTACTTGTTCTTAATTTTTAATACAGCGGAGATGTTTCTTG
CTTTGTTTTCAGACTCTCCTTTTTAATCAGGACAACATTTGAAAGATTTTATTGTGCCTCTAAAGGGTATATTTGGGGGTTGGGTCTTTT
TGTTAAACTCTGGATAGTAATAAGTTTCAGGTCAGTATAGGCCCGAATCATGTGGTTTCAGGTATGTTTTTCTTTTTTCTTTTTCTTTTT
TTTTTTTCTTTTTTTTTTTTTTTTTTTTTGAGGTGGAGTCTCCCTCTGTTGCCCAGGCTGGAGTGCAGTGGCATGATCTCGGCTCACTGC
AACCCTCCACCTCCTGAATTAAAGTGATTCTCCTGCCTCAGCCTCCCGAGTAGCTGGGATTACAGGCACGCACCACTACACCCAGATAAT
TTTTGTATTTTTAGTAGAGACGTGATTTCACCATGTTGGCCAGGCTGGTCTCGAACTCCTGACCTCAGCTGATCTGCCCGCCTTGGCCTC
CCAAAGTGCTGGGATTACAGGCGTGATCCACTGCACCTGGCCTCAGGTATGTTTTTCTATCTACACACAAAAAGTTTATTTTCCTTCCTC
TTATTTGATATCAGAAGAATGACAGGAATCAGTTTTTAACAGAGATAGTTTTTCCGTTTCTCCATTGTGTTAATCAGAGCGCAGACTTAC
ATTCTCAGTCATTTATCTTTTCTGGTGGAGAATAAAAAGTCACTTATAGTTAAAGATCAGAAAATTATCACACCAAATCCATTACATATG
TTAGAATCAATAATTTACTCAAAAATCAGCTTTTATAGGTATGTTGGCACCTTATCCAAGAACTTATCCCTGTTCCAGTACCCCTGTGCT
TCATTCAGTATCAGTAACCCTGCAATGATTTTTACAAATATCTTTTTCTAGTGGGTTTTTTACTTAGAGGAAAGAACTTTGTAATAGCTC
TTAATGTTTATATATAAGAGAAGACAGAATGGAAAATGTTTTTTGAAGTCAAATATTGCATGATGTAAAGAAAAAACTTTAAACTTAAAT
GAGTAGGTTGTCCTGAATTACACTGGTAACTCTCTACTTCTTTATTAAAGAAGTTATAGTAAGATGCCTTTGTTACCTGATTTCAGTGTA
CATTGTTTTTATGTGGTTTTCTGATAATGTCCTGTCAGAATTGTATTGGTTTAGGCCAAAGGCCATAGCAAAAACATAGAGAACAAATAT
GATCTTAAAAATAGATTGTAACATTTTAAACAATTAGTTTAGTAATTTGGGAAATAGTGGATGCATAATACTTTAACAGAAGTCACACAT
CTGTAGGTTTATCTTTTGATTATTCTCCTGAGGCATTAGATAGTTTTTCTATTATAAGTGACAGATTGACTCACTTAATATAAATAAGTA
GCATACACTAAAAGCTTACTATGTGCCAGATACTGTGCTGGACACTTACATAGATAAGCCATTGAATCCACACAGCAGCCCTGTAAGAAA
TAAGTAAAATCTGCATAAAGTGTTGAAATAGGAATATACATTTCATTATGAAAAATGAATAGATTATGCCTATCTGAATCAATATTGCAT
TCAAATAAGTGATTACTTAAATCATATATCATAGTTTACACTCCTTAAAAAAAGGTACATAAATTCAGTGAGGTTTTTTTCTTAACATAC
AGAAGTACTAAATACTGCTTGCAGTATAATATTGATATTGGAAGCTGCAGTTTCCAGAATAAGTGGAGTAATAACTAAACAGACATTTAA
TTTTATTTCAATATCTATGGAAAAAACACTTATTAAATCTCCCTGTATTTTATGTTGTCTTTATTACAGAATCACTTGTCTGTTTGTTGT
GTGCCACTTACTGACAAAACTTTAAACAGTACTTGATGCCAGCTCTCTACTCTGTGGCTGTGGGACCTGTTTCTTTTAGGTACTTGTGCT
TATTAATCTACTTACTAAATTTTCACATTGACATTTTTGGGGATGATACTACCATATACGAAATGGAAAATGTAATATGCTCAGTGCTTC
TGTAAAATGCAGCAATACTGGTATTACTTTACATCAGTAGGCATCTTTGACATGAGCATATAAATATTTTGTTGACTCAGCAAAGGTGAC
ACTTTGTGACTAAAGTATCCCATTATATATAATGTTTTTTGAAATGTTGGAAATTTTGGGGAATTATCAAATGTATAGAAGTTGCATGAA
GGTTATAGAGAGGTGTAACTGTTTGTTAACTATTACATGGATTTCATACTAGGCAGTGACAACTAACATGTTACTTCAACTAAAAGTGTA

>55654_55654_2_MTFR1L-BROX_MTFR1L_chr1_26156304_ENST00000374301_BROX_chr1_222906016_ENST00000340934_length(amino acids)=193AA_BP=171
MPSGCLVLQVQELVQMSGMEATVTIPIWQNKPHGAARSVVRRIGTNLPLKPCARASFETLPNISDLCLRDVPPVPTLADIAWIAADEEET
YARVRSDTRPLRHTWKPSPLIVMQRNASVPNLRGSEERLLALKKPALPALSRTTELQDELSHLRSQIAKIVAADAETESRSHQTSKGHWV

--------------------------------------------------------------
>55654_55654_3_MTFR1L-BROX_MTFR1L_chr1_26156304_ENST00000374303_BROX_chr1_222906016_ENST00000340934_length(transcript)=3200nt_BP=678nt
GTGCGCAGCTGCGGAGGATCGCTTCCGGGGGGCGGGTCAGCGGAAGTGAGGGCGGTTGAGGCTGGGCGGCCCAAGGTGGAAGGAGGGGCC
GTGAGGTGAGAGAGTCCGGGAGCCCGAGCTTGAGATGGCCTGATATGAAGGAGTCACGCCTCCCGCCTCCCGGAGCTGCCCAGTGGCTGC
CTTGTCCTTCAAGTGCAGGAGCTGGTTCAAATGTCAGGAATGGAAGCCACTGTGACCATCCCAATCTGGCAAAACAAGCCACATGGGGCT
GCTCGAAGTGTAGTAAGAAGAATTGGGACCAACCTACCCTTGAAGCCGTGTGCCCGGGCGTCCTTTGAGACCCTGCCCAACATCTCTGAC
CTGTGTTTGAGAGATGTGCCCCCAGTCCCTACCCTGGCTGACATCGCCTGGATTGCTGCGGATGAAGAGGAGACATATGCCCGGGTCAGG
AGTGATACGCGCCCCCTGAGGCACACCTGGAAACCCAGCCCTCTGATTGTCATGCAGCGCAATGCCTCTGTTCCCAACCTGCGTGGGTCC
GAGGAGAGGCTTCTGGCCCTGAAGAAGCCAGCTCTGCCAGCCCTAAGCCGCACTACTGAGCTGCAGGACGAGCTGAGCCACTTGCGCAGC
CAGATTGCAAAGATAGTGGCAGCTGATGCAGAAACAGAGTCAAGATCTCATCAAACCTCAAAAGGACACTGGGTGCTACATCTCCTAAAA
TACAACTTGCACTTAGAATTTCTCTAGCAGTAAATAAGATAAACCACAGAATTTCAGTTCTTATTTCTCAAAATGATTTCTCTGAAGCTT
GTAGAATAACTATTATATTCAGAGGGTTATCTGCCTTCAGCTTACTTGTTCTTAATTTTTAATACAGCGGAGATGTTTCTTGCTTTGTTT
TCAGACTCTCCTTTTTAATCAGGACAACATTTGAAAGATTTTATTGTGCCTCTAAAGGGTATATTTGGGGGTTGGGTCTTTTTGTTAAAC
TCTGGATAGTAATAAGTTTCAGGTCAGTATAGGCCCGAATCATGTGGTTTCAGGTATGTTTTTCTTTTTTCTTTTTCTTTTTTTTTTTTC
TTTTTTTTTTTTTTTTTTTTTGAGGTGGAGTCTCCCTCTGTTGCCCAGGCTGGAGTGCAGTGGCATGATCTCGGCTCACTGCAACCCTCC
ACCTCCTGAATTAAAGTGATTCTCCTGCCTCAGCCTCCCGAGTAGCTGGGATTACAGGCACGCACCACTACACCCAGATAATTTTTGTAT
TTTTAGTAGAGACGTGATTTCACCATGTTGGCCAGGCTGGTCTCGAACTCCTGACCTCAGCTGATCTGCCCGCCTTGGCCTCCCAAAGTG
CTGGGATTACAGGCGTGATCCACTGCACCTGGCCTCAGGTATGTTTTTCTATCTACACACAAAAAGTTTATTTTCCTTCCTCTTATTTGA
TATCAGAAGAATGACAGGAATCAGTTTTTAACAGAGATAGTTTTTCCGTTTCTCCATTGTGTTAATCAGAGCGCAGACTTACATTCTCAG
TCATTTATCTTTTCTGGTGGAGAATAAAAAGTCACTTATAGTTAAAGATCAGAAAATTATCACACCAAATCCATTACATATGTTAGAATC
AATAATTTACTCAAAAATCAGCTTTTATAGGTATGTTGGCACCTTATCCAAGAACTTATCCCTGTTCCAGTACCCCTGTGCTTCATTCAG
TATCAGTAACCCTGCAATGATTTTTACAAATATCTTTTTCTAGTGGGTTTTTTACTTAGAGGAAAGAACTTTGTAATAGCTCTTAATGTT
TATATATAAGAGAAGACAGAATGGAAAATGTTTTTTGAAGTCAAATATTGCATGATGTAAAGAAAAAACTTTAAACTTAAATGAGTAGGT
TGTCCTGAATTACACTGGTAACTCTCTACTTCTTTATTAAAGAAGTTATAGTAAGATGCCTTTGTTACCTGATTTCAGTGTACATTGTTT
TTATGTGGTTTTCTGATAATGTCCTGTCAGAATTGTATTGGTTTAGGCCAAAGGCCATAGCAAAAACATAGAGAACAAATATGATCTTAA
AAATAGATTGTAACATTTTAAACAATTAGTTTAGTAATTTGGGAAATAGTGGATGCATAATACTTTAACAGAAGTCACACATCTGTAGGT
TTATCTTTTGATTATTCTCCTGAGGCATTAGATAGTTTTTCTATTATAAGTGACAGATTGACTCACTTAATATAAATAAGTAGCATACAC
TAAAAGCTTACTATGTGCCAGATACTGTGCTGGACACTTACATAGATAAGCCATTGAATCCACACAGCAGCCCTGTAAGAAATAAGTAAA
ATCTGCATAAAGTGTTGAAATAGGAATATACATTTCATTATGAAAAATGAATAGATTATGCCTATCTGAATCAATATTGCATTCAAATAA
GTGATTACTTAAATCATATATCATAGTTTACACTCCTTAAAAAAAGGTACATAAATTCAGTGAGGTTTTTTTCTTAACATACAGAAGTAC
TAAATACTGCTTGCAGTATAATATTGATATTGGAAGCTGCAGTTTCCAGAATAAGTGGAGTAATAACTAAACAGACATTTAATTTTATTT
CAATATCTATGGAAAAAACACTTATTAAATCTCCCTGTATTTTATGTTGTCTTTATTACAGAATCACTTGTCTGTTTGTTGTGTGCCACT
TACTGACAAAACTTTAAACAGTACTTGATGCCAGCTCTCTACTCTGTGGCTGTGGGACCTGTTTCTTTTAGGTACTTGTGCTTATTAATC
TACTTACTAAATTTTCACATTGACATTTTTGGGGATGATACTACCATATACGAAATGGAAAATGTAATATGCTCAGTGCTTCTGTAAAAT
GCAGCAATACTGGTATTACTTTACATCAGTAGGCATCTTTGACATGAGCATATAAATATTTTGTTGACTCAGCAAAGGTGACACTTTGTG
ACTAAAGTATCCCATTATATATAATGTTTTTTGAAATGTTGGAAATTTTGGGGAATTATCAAATGTATAGAAGTTGCATGAAGGTTATAG
AGAGGTGTAACTGTTTGTTAACTATTACATGGATTTCATACTAGGCAGTGACAACTAACATGTTACTTCAACTAAAAGTGTATAATGGGT

>55654_55654_3_MTFR1L-BROX_MTFR1L_chr1_26156304_ENST00000374303_BROX_chr1_222906016_ENST00000340934_length(amino acids)=193AA_BP=171
MPSGCLVLQVQELVQMSGMEATVTIPIWQNKPHGAARSVVRRIGTNLPLKPCARASFETLPNISDLCLRDVPPVPTLADIAWIAADEEET
YARVRSDTRPLRHTWKPSPLIVMQRNASVPNLRGSEERLLALKKPALPALSRTTELQDELSHLRSQIAKIVAADAETESRSHQTSKGHWV

--------------------------------------------------------------
>55654_55654_4_MTFR1L-BROX_MTFR1L_chr1_26156304_ENST00000374307_BROX_chr1_222906016_ENST00000340934_length(transcript)=3103nt_BP=581nt
GAGAGAGTCCGGGAGCCCGAGCTTGAGATGGCCTGATATGAAGGAGTCACGCCTCCCGCCTCCCGGAGCTGCCCAGTGGCTGCCTTGTCC
TTCAAGTGCAGGAGCTGGTTCAAATGTCAGGAATGGAAGCCACTGTGACCATCCCAATCTGGCAAAACAAGCCACATGGGGCTGCTCGAA
GTGTAGTAAGAAGAATTGGGACCAACCTACCCTTGAAGCCGTGTGCCCGGGCGTCCTTTGAGACCCTGCCCAACATCTCTGACCTGTGTT
TGAGAGATGTGCCCCCAGTCCCTACCCTGGCTGACATCGCCTGGATTGCTGCGGATGAAGAGGAGACATATGCCCGGGTCAGGAGTGATA
CGCGCCCCCTGAGGCACACCTGGAAACCCAGCCCTCTGATTGTCATGCAGCGCAATGCCTCTGTTCCCAACCTGCGTGGGTCCGAGGAGA
GGCTTCTGGCCCTGAAGAAGCCAGCTCTGCCAGCCCTAAGCCGCACTACTGAGCTGCAGGACGAGCTGAGCCACTTGCGCAGCCAGATTG
CAAAGATAGTGGCAGCTGATGCAGAAACAGAGTCAAGATCTCATCAAACCTCAAAAGGACACTGGGTGCTACATCTCCTAAAATACAACT
TGCACTTAGAATTTCTCTAGCAGTAAATAAGATAAACCACAGAATTTCAGTTCTTATTTCTCAAAATGATTTCTCTGAAGCTTGTAGAAT
AACTATTATATTCAGAGGGTTATCTGCCTTCAGCTTACTTGTTCTTAATTTTTAATACAGCGGAGATGTTTCTTGCTTTGTTTTCAGACT
CTCCTTTTTAATCAGGACAACATTTGAAAGATTTTATTGTGCCTCTAAAGGGTATATTTGGGGGTTGGGTCTTTTTGTTAAACTCTGGAT
AGTAATAAGTTTCAGGTCAGTATAGGCCCGAATCATGTGGTTTCAGGTATGTTTTTCTTTTTTCTTTTTCTTTTTTTTTTTTCTTTTTTT
TTTTTTTTTTTTTTGAGGTGGAGTCTCCCTCTGTTGCCCAGGCTGGAGTGCAGTGGCATGATCTCGGCTCACTGCAACCCTCCACCTCCT
GAATTAAAGTGATTCTCCTGCCTCAGCCTCCCGAGTAGCTGGGATTACAGGCACGCACCACTACACCCAGATAATTTTTGTATTTTTAGT
AGAGACGTGATTTCACCATGTTGGCCAGGCTGGTCTCGAACTCCTGACCTCAGCTGATCTGCCCGCCTTGGCCTCCCAAAGTGCTGGGAT
TACAGGCGTGATCCACTGCACCTGGCCTCAGGTATGTTTTTCTATCTACACACAAAAAGTTTATTTTCCTTCCTCTTATTTGATATCAGA
AGAATGACAGGAATCAGTTTTTAACAGAGATAGTTTTTCCGTTTCTCCATTGTGTTAATCAGAGCGCAGACTTACATTCTCAGTCATTTA
TCTTTTCTGGTGGAGAATAAAAAGTCACTTATAGTTAAAGATCAGAAAATTATCACACCAAATCCATTACATATGTTAGAATCAATAATT
TACTCAAAAATCAGCTTTTATAGGTATGTTGGCACCTTATCCAAGAACTTATCCCTGTTCCAGTACCCCTGTGCTTCATTCAGTATCAGT
AACCCTGCAATGATTTTTACAAATATCTTTTTCTAGTGGGTTTTTTACTTAGAGGAAAGAACTTTGTAATAGCTCTTAATGTTTATATAT
AAGAGAAGACAGAATGGAAAATGTTTTTTGAAGTCAAATATTGCATGATGTAAAGAAAAAACTTTAAACTTAAATGAGTAGGTTGTCCTG
AATTACACTGGTAACTCTCTACTTCTTTATTAAAGAAGTTATAGTAAGATGCCTTTGTTACCTGATTTCAGTGTACATTGTTTTTATGTG
GTTTTCTGATAATGTCCTGTCAGAATTGTATTGGTTTAGGCCAAAGGCCATAGCAAAAACATAGAGAACAAATATGATCTTAAAAATAGA
TTGTAACATTTTAAACAATTAGTTTAGTAATTTGGGAAATAGTGGATGCATAATACTTTAACAGAAGTCACACATCTGTAGGTTTATCTT
TTGATTATTCTCCTGAGGCATTAGATAGTTTTTCTATTATAAGTGACAGATTGACTCACTTAATATAAATAAGTAGCATACACTAAAAGC
TTACTATGTGCCAGATACTGTGCTGGACACTTACATAGATAAGCCATTGAATCCACACAGCAGCCCTGTAAGAAATAAGTAAAATCTGCA
TAAAGTGTTGAAATAGGAATATACATTTCATTATGAAAAATGAATAGATTATGCCTATCTGAATCAATATTGCATTCAAATAAGTGATTA
CTTAAATCATATATCATAGTTTACACTCCTTAAAAAAAGGTACATAAATTCAGTGAGGTTTTTTTCTTAACATACAGAAGTACTAAATAC
TGCTTGCAGTATAATATTGATATTGGAAGCTGCAGTTTCCAGAATAAGTGGAGTAATAACTAAACAGACATTTAATTTTATTTCAATATC
TATGGAAAAAACACTTATTAAATCTCCCTGTATTTTATGTTGTCTTTATTACAGAATCACTTGTCTGTTTGTTGTGTGCCACTTACTGAC
AAAACTTTAAACAGTACTTGATGCCAGCTCTCTACTCTGTGGCTGTGGGACCTGTTTCTTTTAGGTACTTGTGCTTATTAATCTACTTAC
TAAATTTTCACATTGACATTTTTGGGGATGATACTACCATATACGAAATGGAAAATGTAATATGCTCAGTGCTTCTGTAAAATGCAGCAA
TACTGGTATTACTTTACATCAGTAGGCATCTTTGACATGAGCATATAAATATTTTGTTGACTCAGCAAAGGTGACACTTTGTGACTAAAG
TATCCCATTATATATAATGTTTTTTGAAATGTTGGAAATTTTGGGGAATTATCAAATGTATAGAAGTTGCATGAAGGTTATAGAGAGGTG
TAACTGTTTGTTAACTATTACATGGATTTCATACTAGGCAGTGACAACTAACATGTTACTTCAACTAAAAGTGTATAATGGGTTGTCTTT

>55654_55654_4_MTFR1L-BROX_MTFR1L_chr1_26156304_ENST00000374307_BROX_chr1_222906016_ENST00000340934_length(amino acids)=193AA_BP=171
MPSGCLVLQVQELVQMSGMEATVTIPIWQNKPHGAARSVVRRIGTNLPLKPCARASFETLPNISDLCLRDVPPVPTLADIAWIAADEEET
YARVRSDTRPLRHTWKPSPLIVMQRNASVPNLRGSEERLLALKKPALPALSRTTELQDELSHLRSQIAKIVAADAETESRSHQTSKGHWV

--------------------------------------------------------------
>55654_55654_5_MTFR1L-BROX_MTFR1L_chr1_26156304_ENST00000524618_BROX_chr1_222906016_ENST00000340934_length(transcript)=3143nt_BP=621nt
AGGAGGGGCCGTGAGGTGAGAGAGTCCGGGAGCCCGAGCTTGAGATGGCCTGATATGAAGGAGTCACGCCTCCCGCCTCCCGGAGCTGCC
CAGTGGCTGCCTTGTCCTTCAAGTGCAGGAGCTGGTTCAAATGTCAGGAATGGAAGCCACTGTGCTGTCTCCGTCTCTTTGCTCCAGACC
ATCCCAATCTGGCAAAACAAGCCACATGGGGCTGCTCGAAGTGTAGTAAGAAGAATTGGGACCAACCTACCCTTGAAGCCGTGTGCCCGG
GCGTCCTTTGAGACCCTGCCCAACATCTCTGACCTGTGTTTGAGAGATGTGCCCCCAGTCCCTACCCTGGCTGACATCGCCTGGATTGCT
GCGGATGAAGAGGAGACATATGCCCGGGTCAGGAGTGATACGCGCCCCCTGAGGCACACCTGGAAACCCAGCCCTCTGATTGTCATGCAG
CGCAATGCCTCTGTTCCCAACCTGCGTGGGTCCGAGGAGAGGCTTCTGGCCCTGAAGAAGCCAGCTCTGCCAGCCCTAAGCCGCACTACT
GAGCTGCAGGACGAGCTGAGCCACTTGCGCAGCCAGATTGCAAAGATAGTGGCAGCTGATGCAGAAACAGAGTCAAGATCTCATCAAACC
TCAAAAGGACACTGGGTGCTACATCTCCTAAAATACAACTTGCACTTAGAATTTCTCTAGCAGTAAATAAGATAAACCACAGAATTTCAG
TTCTTATTTCTCAAAATGATTTCTCTGAAGCTTGTAGAATAACTATTATATTCAGAGGGTTATCTGCCTTCAGCTTACTTGTTCTTAATT
TTTAATACAGCGGAGATGTTTCTTGCTTTGTTTTCAGACTCTCCTTTTTAATCAGGACAACATTTGAAAGATTTTATTGTGCCTCTAAAG
GGTATATTTGGGGGTTGGGTCTTTTTGTTAAACTCTGGATAGTAATAAGTTTCAGGTCAGTATAGGCCCGAATCATGTGGTTTCAGGTAT
GTTTTTCTTTTTTCTTTTTCTTTTTTTTTTTTCTTTTTTTTTTTTTTTTTTTTTGAGGTGGAGTCTCCCTCTGTTGCCCAGGCTGGAGTG
CAGTGGCATGATCTCGGCTCACTGCAACCCTCCACCTCCTGAATTAAAGTGATTCTCCTGCCTCAGCCTCCCGAGTAGCTGGGATTACAG
GCACGCACCACTACACCCAGATAATTTTTGTATTTTTAGTAGAGACGTGATTTCACCATGTTGGCCAGGCTGGTCTCGAACTCCTGACCT
CAGCTGATCTGCCCGCCTTGGCCTCCCAAAGTGCTGGGATTACAGGCGTGATCCACTGCACCTGGCCTCAGGTATGTTTTTCTATCTACA
CACAAAAAGTTTATTTTCCTTCCTCTTATTTGATATCAGAAGAATGACAGGAATCAGTTTTTAACAGAGATAGTTTTTCCGTTTCTCCAT
TGTGTTAATCAGAGCGCAGACTTACATTCTCAGTCATTTATCTTTTCTGGTGGAGAATAAAAAGTCACTTATAGTTAAAGATCAGAAAAT
TATCACACCAAATCCATTACATATGTTAGAATCAATAATTTACTCAAAAATCAGCTTTTATAGGTATGTTGGCACCTTATCCAAGAACTT
ATCCCTGTTCCAGTACCCCTGTGCTTCATTCAGTATCAGTAACCCTGCAATGATTTTTACAAATATCTTTTTCTAGTGGGTTTTTTACTT
AGAGGAAAGAACTTTGTAATAGCTCTTAATGTTTATATATAAGAGAAGACAGAATGGAAAATGTTTTTTGAAGTCAAATATTGCATGATG
TAAAGAAAAAACTTTAAACTTAAATGAGTAGGTTGTCCTGAATTACACTGGTAACTCTCTACTTCTTTATTAAAGAAGTTATAGTAAGAT
GCCTTTGTTACCTGATTTCAGTGTACATTGTTTTTATGTGGTTTTCTGATAATGTCCTGTCAGAATTGTATTGGTTTAGGCCAAAGGCCA
TAGCAAAAACATAGAGAACAAATATGATCTTAAAAATAGATTGTAACATTTTAAACAATTAGTTTAGTAATTTGGGAAATAGTGGATGCA
TAATACTTTAACAGAAGTCACACATCTGTAGGTTTATCTTTTGATTATTCTCCTGAGGCATTAGATAGTTTTTCTATTATAAGTGACAGA
TTGACTCACTTAATATAAATAAGTAGCATACACTAAAAGCTTACTATGTGCCAGATACTGTGCTGGACACTTACATAGATAAGCCATTGA
ATCCACACAGCAGCCCTGTAAGAAATAAGTAAAATCTGCATAAAGTGTTGAAATAGGAATATACATTTCATTATGAAAAATGAATAGATT
ATGCCTATCTGAATCAATATTGCATTCAAATAAGTGATTACTTAAATCATATATCATAGTTTACACTCCTTAAAAAAAGGTACATAAATT
CAGTGAGGTTTTTTTCTTAACATACAGAAGTACTAAATACTGCTTGCAGTATAATATTGATATTGGAAGCTGCAGTTTCCAGAATAAGTG
GAGTAATAACTAAACAGACATTTAATTTTATTTCAATATCTATGGAAAAAACACTTATTAAATCTCCCTGTATTTTATGTTGTCTTTATT
ACAGAATCACTTGTCTGTTTGTTGTGTGCCACTTACTGACAAAACTTTAAACAGTACTTGATGCCAGCTCTCTACTCTGTGGCTGTGGGA
CCTGTTTCTTTTAGGTACTTGTGCTTATTAATCTACTTACTAAATTTTCACATTGACATTTTTGGGGATGATACTACCATATACGAAATG
GAAAATGTAATATGCTCAGTGCTTCTGTAAAATGCAGCAATACTGGTATTACTTTACATCAGTAGGCATCTTTGACATGAGCATATAAAT
ATTTTGTTGACTCAGCAAAGGTGACACTTTGTGACTAAAGTATCCCATTATATATAATGTTTTTTGAAATGTTGGAAATTTTGGGGAATT
ATCAAATGTATAGAAGTTGCATGAAGGTTATAGAGAGGTGTAACTGTTTGTTAACTATTACATGGATTTCATACTAGGCAGTGACAACTA

>55654_55654_5_MTFR1L-BROX_MTFR1L_chr1_26156304_ENST00000524618_BROX_chr1_222906016_ENST00000340934_length(amino acids)=216AA_BP=194
MRWPDMKESRLPPPGAAQWLPCPSSAGAGSNVRNGSHCAVSVSLLQTIPIWQNKPHGAARSVVRRIGTNLPLKPCARASFETLPNISDLC
LRDVPPVPTLADIAWIAADEEETYARVRSDTRPLRHTWKPSPLIVMQRNASVPNLRGSEERLLALKKPALPALSRTTELQDELSHLRSQI

--------------------------------------------------------------

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Fusion Gene PPI Analysis for MTFR1L-BROX


check button Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in

ChiPPI page.


check button Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160)
HgeneHgene's interactorsTgeneTgene's interactors


check button - Retained PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenStill interaction with


check button - Lost PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


check button - Retained PPIs, but lost function due to frame-shift fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


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Related Drugs for MTFR1L-BROX


check button Drugs targeting genes involved in this fusion gene.
(DrugBank Version 5.1.8 2021-05-08)
PartnerGeneUniProtAccDrugBank IDDrug nameDrug activityDrug typeDrug status

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Related Diseases for MTFR1L-BROX


check button Diseases associated with fusion partners.
(DisGeNet 4.0)
PartnerGeneDisease IDDisease name# pubmedsSource