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Center for Computational Systems Medicine
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Fusion Gene Summary

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Fusion Gene ORF analysis

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Fusion Genomic Features

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Fusion Protein Features

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Fusion Gene Sequence

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Fusion Gene PPI analysis

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Related Drugs

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Related Diseases

Fusion gene:MTMR10-TSPAN14 (FusionGDB2 ID:55722)

Fusion Gene Summary for MTMR10-TSPAN14

check button Fusion gene summary
Fusion gene informationFusion gene name: MTMR10-TSPAN14
Fusion gene ID: 55722
HgeneTgene
Gene symbol

MTMR10

TSPAN14

Gene ID

54893

81619

Gene namemyotubularin related protein 10tetraspanin 14
Synonyms-DC-TM4F2|TM4SF14|tspan-14
Cytomap

15q13.3

10q23.1

Type of geneprotein-codingprotein-coding
Descriptionmyotubularin-related protein 10inactive phosphatidylinositol 3-phosphatase 10tetraspanin-14tetraspanin similar to TM4SF9transmembrane 4 superfamily member 14
Modification date2020032020200313
UniProtAcc..
Ensembl transtripts involved in fusion geneENST00000425768, ENST00000435680, 
ENST00000563714, ENST00000314404, 
ENST00000265450, ENST00000341863, 
ENST00000372156, ENST00000372158, 
ENST00000372164, ENST00000481124, 
ENST00000429989, 
Fusion gene scores* DoF score2 X 2 X 1=410 X 10 X 3=300
# samples 211
** MAII scorelog2(2/4*10)=2.32192809488736log2(11/300*10)=-1.44745897697122
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0
Context

PubMed: MTMR10 [Title/Abstract] AND TSPAN14 [Title/Abstract] AND fusion [Title/Abstract]

Most frequent breakpointMTMR10(31266517)-TSPAN14(82264482), # samples:1
Anticipated loss of major functional domain due to fusion event.
* DoF score (Degree of Frequency) = # partners X # break points X # cancer types
** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)

check button Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez
PartnerGeneGO IDGO termPubMed ID

check buttonFusion gene breakpoints across MTMR10 (5'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check buttonFusion gene breakpoints across TSPAN14 (3'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check button Fusion gene information from two resources (ChiTars 5.0 and ChimerDB 4.0)
* All genome coordinats were lifted-over on hg19.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
SourceDiseaseSampleHgeneHchrHbpHstrandTgeneTchrTbpTstrand
ChiTaRS5.0N/ABG389369MTMR10chr15

31266517

-TSPAN14chr10

82264482

+


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Fusion Gene ORF analysis for MTMR10-TSPAN14

check button Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
ORFHenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrand
5CDS-intronENST00000425768ENST00000265450MTMR10chr15

31266517

-TSPAN14chr10

82264482

+
5CDS-intronENST00000425768ENST00000341863MTMR10chr15

31266517

-TSPAN14chr10

82264482

+
5CDS-intronENST00000425768ENST00000372156MTMR10chr15

31266517

-TSPAN14chr10

82264482

+
5CDS-intronENST00000425768ENST00000372158MTMR10chr15

31266517

-TSPAN14chr10

82264482

+
5CDS-intronENST00000425768ENST00000372164MTMR10chr15

31266517

-TSPAN14chr10

82264482

+
5CDS-intronENST00000425768ENST00000481124MTMR10chr15

31266517

-TSPAN14chr10

82264482

+
5CDS-intronENST00000435680ENST00000265450MTMR10chr15

31266517

-TSPAN14chr10

82264482

+
5CDS-intronENST00000435680ENST00000341863MTMR10chr15

31266517

-TSPAN14chr10

82264482

+
5CDS-intronENST00000435680ENST00000372156MTMR10chr15

31266517

-TSPAN14chr10

82264482

+
5CDS-intronENST00000435680ENST00000372158MTMR10chr15

31266517

-TSPAN14chr10

82264482

+
5CDS-intronENST00000435680ENST00000372164MTMR10chr15

31266517

-TSPAN14chr10

82264482

+
5CDS-intronENST00000435680ENST00000481124MTMR10chr15

31266517

-TSPAN14chr10

82264482

+
5CDS-intronENST00000563714ENST00000265450MTMR10chr15

31266517

-TSPAN14chr10

82264482

+
5CDS-intronENST00000563714ENST00000341863MTMR10chr15

31266517

-TSPAN14chr10

82264482

+
5CDS-intronENST00000563714ENST00000372156MTMR10chr15

31266517

-TSPAN14chr10

82264482

+
5CDS-intronENST00000563714ENST00000372158MTMR10chr15

31266517

-TSPAN14chr10

82264482

+
5CDS-intronENST00000563714ENST00000372164MTMR10chr15

31266517

-TSPAN14chr10

82264482

+
5CDS-intronENST00000563714ENST00000481124MTMR10chr15

31266517

-TSPAN14chr10

82264482

+
5UTR-3CDSENST00000314404ENST00000429989MTMR10chr15

31266517

-TSPAN14chr10

82264482

+
5UTR-intronENST00000314404ENST00000265450MTMR10chr15

31266517

-TSPAN14chr10

82264482

+
5UTR-intronENST00000314404ENST00000341863MTMR10chr15

31266517

-TSPAN14chr10

82264482

+
5UTR-intronENST00000314404ENST00000372156MTMR10chr15

31266517

-TSPAN14chr10

82264482

+
5UTR-intronENST00000314404ENST00000372158MTMR10chr15

31266517

-TSPAN14chr10

82264482

+
5UTR-intronENST00000314404ENST00000372164MTMR10chr15

31266517

-TSPAN14chr10

82264482

+
5UTR-intronENST00000314404ENST00000481124MTMR10chr15

31266517

-TSPAN14chr10

82264482

+
In-frameENST00000425768ENST00000429989MTMR10chr15

31266517

-TSPAN14chr10

82264482

+
In-frameENST00000435680ENST00000429989MTMR10chr15

31266517

-TSPAN14chr10

82264482

+
In-frameENST00000563714ENST00000429989MTMR10chr15

31266517

-TSPAN14chr10

82264482

+

check buttonORFfinder result based on the fusion transcript sequence of in-frame fusion genes.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandSeq length
(transcript)		BP loci
(transcript)		Predicted start
(transcript)		Predicted stop
(transcript)		Seq length
(amino acids)
ENST00000435680MTMR10chr1531266517-ENST00000429989TSPAN14chr1082264482+16451572981303401
ENST00000425768MTMR10chr1531266517-ENST00000429989TSPAN14chr1082264482+16451572981303401
ENST00000563714MTMR10chr1531266517-ENST00000429989TSPAN14chr1082264482+164515721401303387

check buttonDeepORF prediction of the coding potential based on the fusion transcript sequence of in-frame fusion genes. DeepORF is a coding potential classifier based on convolutional neural network by comparing the real Ribo-seq data. If the no-coding score < 0.5 and coding score > 0.5, then the in-frame fusion transcript is predicted as being likely translated.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandNo-coding scoreCoding score
ENST00000435680ENST00000429989MTMR10chr1531266517-TSPAN14chr1082264482+0.0010208710.9989792
ENST00000425768ENST00000429989MTMR10chr1531266517-TSPAN14chr1082264482+0.0010208710.9989792
ENST00000563714ENST00000429989MTMR10chr1531266517-TSPAN14chr1082264482+0.0016929360.9983071

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Fusion Genomic Features for MTMR10-TSPAN14


check buttonFusionAI prediction of the potential fusion gene breakpoint based on the pre-mature RNA sequence context (+/- 5kb of individual partner genes, total 20kb length sequence). FusionAI is a fusion gene breakpoint classifier based on convolutional neural network by comparing the fusion positive and negative sequence context of ~ 20K fusion gene data. From here, we can have the relative potentency of the 20K genomic sequence how individual sequnce will be likely used as the gene fusion breakpoints.
HgeneHchrHbpHstrandTgeneTchrTbpTstrand1-pp (fusion gene breakpoint)

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions. We integrated a total of 44 different types of human genomic feature loci information across five big categories including virus integration sites, repeats, structural variants, chromatin states, and gene expression regulation. More details are in help page.
genomic feature

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions that are ovelapped with the top 1% feature importance score regions. More details are in help page.
genomic feature of top 1%

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Fusion Protein Features for MTMR10-TSPAN14


check button Four levels of functional features of fusion genes
Go to FGviewer search page for the most frequent breakpoint (https://ccsmweb.uth.edu/FGviewer/chr15:31266517/chr10:82264482)
- FGviewer provides the online visualization of the retention search of the protein functional features across DNA, RNA, protein, and pathological levels.
- How to search
1. Put your fusion gene symbol.
2. Press the tab key until there will be shown the breakpoint information filled.
4. Go down and press 'Search' tab twice.
4. Go down to have the hyperlink of the search result.
5. Click the hyperlink.
6. See the FGviewer result for your fusion gene.
FGviewer

check buttonMain function of each fusion partner protein. (from UniProt)
HgeneTgene
..
FUNCTION: Transcriptional activator which is required for calcium-dependent dendritic growth and branching in cortical neurons. Recruits CREB-binding protein (CREBBP) to nuclear bodies. Component of the CREST-BRG1 complex, a multiprotein complex that regulates promoter activation by orchestrating a calcium-dependent release of a repressor complex and a recruitment of an activator complex. In resting neurons, transcription of the c-FOS promoter is inhibited by BRG1-dependent recruitment of a phospho-RB1-HDAC1 repressor complex. Upon calcium influx, RB1 is dephosphorylated by calcineurin, which leads to release of the repressor complex. At the same time, there is increased recruitment of CREBBP to the promoter by a CREST-dependent mechanism, which leads to transcriptional activation. The CREST-BRG1 complex also binds to the NR2B promoter, and activity-dependent induction of NR2B expression involves a release of HDAC1 and recruitment of CREBBP (By similarity). {ECO:0000250}.FUNCTION: Transcriptional activator which is required for calcium-dependent dendritic growth and branching in cortical neurons. Recruits CREB-binding protein (CREBBP) to nuclear bodies. Component of the CREST-BRG1 complex, a multiprotein complex that regulates promoter activation by orchestrating a calcium-dependent release of a repressor complex and a recruitment of an activator complex. In resting neurons, transcription of the c-FOS promoter is inhibited by BRG1-dependent recruitment of a phospho-RB1-HDAC1 repressor complex. Upon calcium influx, RB1 is dephosphorylated by calcineurin, which leads to release of the repressor complex. At the same time, there is increased recruitment of CREBBP to the promoter by a CREST-dependent mechanism, which leads to transcriptional activation. The CREST-BRG1 complex also binds to the NR2B promoter, and activity-dependent induction of NR2B expression involves a release of HDAC1 and recruitment of CREBBP (By similarity). {ECO:0000250}.

check buttonRetention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at

download page


* Minus value of BPloci means that the break pointn is located before the CDS.
- In-frame and retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
TgeneTSPAN14chr15:31266517chr10:82264482ENST00000372156412254_27027271.0Topological domainCytoplasmic
TgeneTSPAN14chr15:31266517chr10:82264482ENST0000037215641239_6127271.0Topological domainExtracellular
TgeneTSPAN14chr15:31266517chr10:82264482ENST0000037215641283_9227271.0Topological domainCytoplasmic
TgeneTSPAN14chr15:31266517chr10:82264482ENST00000372158311254_27027271.0Topological domainCytoplasmic
TgeneTSPAN14chr15:31266517chr10:82264482ENST0000037215831139_6127271.0Topological domainExtracellular
TgeneTSPAN14chr15:31266517chr10:82264482ENST0000037215831183_9227271.0Topological domainCytoplasmic
TgeneTSPAN14chr15:31266517chr10:82264482ENST00000372164081_170254.0Topological domainCytoplasmic
TgeneTSPAN14chr15:31266517chr10:82264482ENST0000037216408254_2700254.0Topological domainCytoplasmic
TgeneTSPAN14chr15:31266517chr10:82264482ENST000003721640839_610254.0Topological domainExtracellular
TgeneTSPAN14chr15:31266517chr10:82264482ENST000003721640883_920254.0Topological domainCytoplasmic
TgeneTSPAN14chr15:31266517chr10:82264482ENST0000042998919254_27027271.0Topological domainCytoplasmic
TgeneTSPAN14chr15:31266517chr10:82264482ENST000004299891939_6127271.0Topological domainExtracellular
TgeneTSPAN14chr15:31266517chr10:82264482ENST000004299891983_9227271.0Topological domainCytoplasmic
TgeneTSPAN14chr15:31266517chr10:82264482ENST00000481124061_170148.0Topological domainCytoplasmic
TgeneTSPAN14chr15:31266517chr10:82264482ENST0000048112406254_2700148.0Topological domainCytoplasmic
TgeneTSPAN14chr15:31266517chr10:82264482ENST000004811240639_610148.0Topological domainExtracellular
TgeneTSPAN14chr15:31266517chr10:82264482ENST000004811240683_920148.0Topological domainCytoplasmic
TgeneTSPAN14chr15:31266517chr10:82264482ENST00000372156412233_25327271.0TransmembraneHelical
TgeneTSPAN14chr15:31266517chr10:82264482ENST0000037215641262_8227271.0TransmembraneHelical
TgeneTSPAN14chr15:31266517chr10:82264482ENST0000037215641293_11327271.0TransmembraneHelical
TgeneTSPAN14chr15:31266517chr10:82264482ENST00000372158311233_25327271.0TransmembraneHelical
TgeneTSPAN14chr15:31266517chr10:82264482ENST0000037215831162_8227271.0TransmembraneHelical
TgeneTSPAN14chr15:31266517chr10:82264482ENST0000037215831193_11327271.0TransmembraneHelical
TgeneTSPAN14chr15:31266517chr10:82264482ENST000003721640818_380254.0TransmembraneHelical
TgeneTSPAN14chr15:31266517chr10:82264482ENST0000037216408233_2530254.0TransmembraneHelical
TgeneTSPAN14chr15:31266517chr10:82264482ENST000003721640862_820254.0TransmembraneHelical
TgeneTSPAN14chr15:31266517chr10:82264482ENST000003721640893_1130254.0TransmembraneHelical
TgeneTSPAN14chr15:31266517chr10:82264482ENST0000042998919233_25327271.0TransmembraneHelical
TgeneTSPAN14chr15:31266517chr10:82264482ENST000004299891962_8227271.0TransmembraneHelical
TgeneTSPAN14chr15:31266517chr10:82264482ENST000004299891993_11327271.0TransmembraneHelical
TgeneTSPAN14chr15:31266517chr10:82264482ENST000004811240618_380148.0TransmembraneHelical
TgeneTSPAN14chr15:31266517chr10:82264482ENST0000048112406233_2530148.0TransmembraneHelical
TgeneTSPAN14chr15:31266517chr10:82264482ENST000004811240662_820148.0TransmembraneHelical
TgeneTSPAN14chr15:31266517chr10:82264482ENST000004811240693_1130148.0TransmembraneHelical

- In-frame and not-retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneMTMR10chr15:31266517chr10:82264482ENST00000425768-515198_2131581270.6666666666667Compositional biasNote=Poly-Gly
HgeneMTMR10chr15:31266517chr10:82264482ENST00000435680-516198_213158778.0Compositional biasNote=Poly-Gly
HgeneMTMR10chr15:31266517chr10:82264482ENST00000563714-515198_21376452.0Compositional biasNote=Poly-Gly
HgeneMTMR10chr15:31266517chr10:82264482ENST00000425768-515221_6611581270.6666666666667DomainMyotubularin phosphatase
HgeneMTMR10chr15:31266517chr10:82264482ENST00000435680-516221_661158778.0DomainMyotubularin phosphatase
HgeneMTMR10chr15:31266517chr10:82264482ENST00000563714-515221_66176452.0DomainMyotubularin phosphatase
TgeneTSPAN14chr15:31266517chr10:82264482ENST000003721564121_1727271.0Topological domainCytoplasmic
TgeneTSPAN14chr15:31266517chr10:82264482ENST000003721583111_1727271.0Topological domainCytoplasmic
TgeneTSPAN14chr15:31266517chr10:82264482ENST00000429989191_1727271.0Topological domainCytoplasmic
TgeneTSPAN14chr15:31266517chr10:82264482ENST0000037215641218_3827271.0TransmembraneHelical
TgeneTSPAN14chr15:31266517chr10:82264482ENST0000037215831118_3827271.0TransmembraneHelical
TgeneTSPAN14chr15:31266517chr10:82264482ENST000004299891918_3827271.0TransmembraneHelical


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Fusion Gene Sequence for MTMR10-TSPAN14


check button For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. To have fusion amino acid sequence, we ran ORFfinder and chose the longest ORF among the all predicted ones.
>55722_55722_1_MTMR10-TSPAN14_MTMR10_chr15_31266517_ENST00000425768_TSPAN14_chr10_82264482_ENST00000429989_length(transcript)=16451nt_BP=572nt
AGAAAGGGCCTGGGCGGCCGCACTGAGAGCTTTACGCCCGGAGGCGTCGGCGCTGCCACTGGCCCGCGACGGGAACGGGGCGAAAAGGCG
GCGGCACCATGTTCTCCCTCAAGCCGCCCAAACCCACCTTCAGGTCCTACCTCCTGCCACCGCCCCAGACTGACGATAAGATCAATTCGG
AACCGAAGATTAAAAAACTGGAGCCAGTCCTTTTGCCAGGAGAAATTGTCGTAAATGAAGTCAATTTTGTGAGAAAATGCATTGCAACAG
ACACAAGCCAGTACGATTTGTGGGGAAAGCTGATATGCAGTAACTTCAAAATCTCCTTTATTACAGATGACCCAATGCCATTACAGAAAT
TCCATTACAGAAACCTTCTTCTTGGTGAACACGATGTCCCTTTAACATGTATTGAGCAAATTGTCACAGTAAACGACCACAAGAGGAAGC
AGAAAGTCCTAGGCCCCAACCAGAAACTGAAATTTAATCCAACAGAGTTAATTATTTATTGTAAAGATTTCAGAATTGTCAGATTTCGCT
TTGATGAATCAGGTCCCGAAAGTGCTAAAAAGTTGGCTGGAGTTGTCTTCCTTGGAGTCGGGCTGTGGGCATGGAGCGAAAAGGGTGTGC
TGTCCGACCTCACCAAAGTGACCCGGATGCATGGAATCGACCCTGTGGTGCTGGTCCTGATGGTGGGCGTGGTGATGTTCACCCTGGGGT
TCGCCGGCTGCGTGGGGGCTCTGCGGGAGAATATCTGCTTGCTCAACTTTTTCTGTGGCACCATCGTGCTCATCTTCTTCCTGGAGCTGG
CTGTGGCCGTGCTGGCCTTCCTGTTCCAGGACTGGGTGAGGGACCGGTTCCGGGAGTTCTTCGAGAGCAACATCAAGTCCTACCGGGACG
ATATCGATCTGCAAAACCTCATCGACTCCCTTCAGAAAGCTAACCAGTGCTGTGGCGCATATGGCCCTGAAGACTGGGACCTCAACGTCT
ACTTCAATTGCAGCGGTGCCAGCTACAGCCGAGAGAAGTGCGGGGTCCCCTTCTCCTGCTGCGTGCCAGATCCTGCGCAAAAAGTTGTGA
ACACACAGTGTGGATATGATGTCAGGATTCAGCTGAAGAGCAAGTGGGATGAGTCCATCTTCACGAAAGGCTGCATCCAGGCGCTGGAAA
GCTGGCTCCCGCGGAACATTTACATTGTGGCTGGCGTCTTCATCGCCATCTCGCTGTTGCAGATATTTGGCATCTTCCTGGCAAGGACGC
TGATCTCAGACATCGAGGCAGTGAAGGCCGGCCATCACTTCTGAGGAGCAGAGTTGAGGGAGCCGAGCTGAGCCACGCTGGGAGGCCAGA
GCCTTTCTCTGCCATCAGCCCTACGTCCAGAGGGAGAGGAGCCGACACCCCCAGAGCCAGTGCCCCATCTTAAGCATCAGCGTGACGTGA
CCTCTCTGTTTCTGCTTGCTGGTGCTGAAGACCAAGGGTCCCCCTTGTTACCTGCCCAAACTTGTGACTGCATCCCTCTGGAGTCTACCC
AGAGACAGAGAATGTGTCTTTATGTGGGAGTGGTGACTCTGAAAGACAGAGAGGGCTCCTGTGGCTGCCAGGAGGGCTTGACTCAGACCC
CCTGCAGCTCAAGCATGTCTGCAGGACACCCTGGTCCCCTCTCCACTGGCATCCAGACATCTGCTTTGGGTCATCCACATCTGTGGGTGG
GCCGTGGGTAGAGGGACCCACAGGCGTGGACAGGGCATCTCTCTCCATCAAGCAAAGCAGCATGGGGGCCTGCCCGTAACGGGAGGCGGA
CGTGGCCCCGCTGGGCCTCTGAGTGCCAGCGCAGTCTGCTGGGACATGCACATATCAGGGGTTGTTTGCAGGATCCTCAGCCATGTTCAA
GTGAAGTAAGCCTGAGCCAGTGCGTGGACTGGTGCCACGGGAGTGCCTTGTCCACTGTCCCCCTGTGTCCACCAGCTATTCTCCTGGCGC
CGGAACTGCCTCTGGTCTTGATAGCATTAAGCCCTGATGGCGCCGGTGGCGCGGTGGGCATGGTTCTTCACTGAGAGCCGGCTCTCCTTT
TCTTAAAGTGTGTAAATAGTTTATTTATAGGGGTAAGAATGTTCTCACACCATTTCACTTCCTCTTCCTCTCCTCCAGCATTCTCCTCTG
AGCAGCCTTAGATAGTGTCCATGGCTGGAGCCGACCCTTTGAGTCCCCTTGAGTGTCTTAAGAACCAGCCCACAACAGCCTCTCTTTCTC
CTCCACATACTGCAGCCTCCCTCCATGCATCCCACATACAAGCACTCCCCCACTCCCCAGCGTGGCCTCACTGTCTTCTGGTCTTGGTGC
TACTGAAATTGTCACCCAGAATTTGAATCCTGACCCTCCCCACTGCAAGCCCAGGGAGCCCCAGCCCAAGATGGCCAGCCTGAAACTGTT
GGCCAGGGCTCCTCTTGTGGCCATGTACCCAGGGCTGGCTGGCCTGCCATTTGCCTCTCCCCGGAGACAGCCGTTCTTCTGCAACCACAC
CCCGTGCCTAGCCACAACCCCAGGCTGCAGCTGCTCAGAAGCTCCAGGCATTTTGTTTCTGGTGACCGCCCCTAATGGGATATCGGTGAT
CACTGGTCCACCCTTCCTGTCAGGGCTTTTCTGGGGCTGCTCTTGGAAATGAAGTCTTAAGTACTGAATAACTCCCCTGGGGATAGCTGG
GGCATTTGTCTAGCTGGGCTACTTTCTAACACTTTGCCATAGCTCAGACCACTTCTCATCGTTCAGGGATGGACTGCAACCTTAATTTAC
TTGCCGGAGTGTACATTCTAGTGTGGTGTATACTGGTGGCTGTTGATGATGATTTTTTTTTTTTTACACAATTCTCTGTAGACTAGGAGA
AGAATGCTTGTGTTTTTCGGAAGTGTGATGCTTCTCTTTGACTGCCAAACTCTTTTATGGAATATATCTTTATATTAATGCTGTTTTGGT
CATTTTTGTTTGGGGTCACTATTGAGATATTGCTAAGCATCTCAGTGGTAAACGCGGCTGCCAGAGGAACCAAGGGATAGGGTATGTAGA
CCTTACAGAAGGATGGATGGTAAAGGCAGTCCATCATCAGCACAATCTGACTTACATTTCATTGAGTAATTTTTTTTTTTTTTAAGATTC
TGTATGGCAGCACTTTCAGTTGCCCTTGTGTGCCGGCCACAGCCGCACAAGTTGGCTTGTGGTTTATCCCCCGCTATAAGTGAGAGCTGG
AGAAACTTCAACTCCATAGGTCTAGAGGAAACATTGTTTTAGGTTATTTCTGTCCACCCCTGTGCGATACTATTTATTGATCCAAGCAGA
AGAGCTTGGGGACACTGAGTCGAAGTGGGGACATGGGATTGAAGCCTGGGCACTGCTGCTGCATGAGCTGTGTGTCCTGGGTGTGCCGGC
CTTTCTGTGAAGGGGGTTGGTGGCAGTGCCCACCTCACTAGATGCCTCTGACCCAGCCTCCCCTGGGGGAGTGGGTGGCCACAGACCCTC
CCTGCCAGAGCTCCTGGAAGGCTCCTGCAGGCCTGACCCATCTATTCCTGTAGACCTGGTTTAGGATGAAGTCTCGGTGCGATTTTTGCA
GAGTTGGGTTTATCTTTCAACTATAGACCCTTCTGGCTGTTCTCAGCCATATCATGTGACTCTGAATAGTTGGATGAGGAATGGAAAGAA
AGCAAGGATGAGAGCCGGTCACGTGGCAGTCTCCGCCCAGCATCGGCTGTCCGCACAGAGGCACAGGGCAGGCCTCCTGTGCACTCCCCA
CCTAGCACTGGCCTGTCCTGAATCCCCGCCTTCCCTGGTTGGAGGCCAGCTGTGGCATTTGCACCCTCTTCTCACCTCACCATGCACATG
CTAACTTTAAAGCCTTGGGGTCTTTCCTGTACCCCCTCCTCAACCCTGGTCCACCCCCTCTCAGGATCTTGTCAACGTTATTTTTCCTGT
CCCGTCTTCCTATCGCTGGCCTTCCTTTCCCATCCTAAAAACTTGCCGAGGCCCTATGGCTCCCTCCCTTTCTTTCCCAGGCAGCTTCTT
ATCTGGGCTGTCTGTACCCCTTCCTTTGCACCACCCACCATGCCCCACGTAGCTGAAAGCTGCTTATCCCAATTGTCAACTCTGGCCTTC
TTCAGCCTCTGTAGCACCAGACACTGCACCTCCTGAATGTCCTCTGCTTCTCTGCTTCAGAGGCCCAGGCTCGCCAGTTCTCTGACCTCT
CCCATATGTCTGCTTAGGACTCTGCTGCAGCTGTCCTCACCAGCCTCCGGGGAATCCCACTACCCACAGGGCAGGGCTGTGGGCTGGGCT
GAAAAACCATCTGCATGGTCCACAAGAAGCCTGGCACTGGGTTTCCCCATGAATAACAATGAAAATTAATGGATGCACAACCTTCCTGGA
ACGTGGAATTTCTCTGGGAGATTCCATGCAGAGGCCACTGGGGAGGTGGCAGGCATGCATGTGACTGTAGGTGGCTGCAGTGTTGGAAGG
CTCCCAGCAGAGCAGAGAGGGTGTCAGTCTCATCAGGGAACCCACCTGATGGCTTCTCAGCCAGCAGTCTCAGAGGAACATAGACGACTG
CTGAGAAAGGAGGGAGGCAGCAGTGGTCCCAGCACCTGAGGCATCCTGCTGTCATGGGAAGGTCTCCGCCCAAATGTCAGATGCATCAGC
CTGTCACCCGCTGGTCCAGAGCTTTCAGCTGTACTGGTAGGGGGTGGGTGGTGGAGTGCTGAATGACCTTCACAGGTGGGCCTTTCCAGC
TCTAGGGTCTTACGGGTGTCGGTCCACAGAACCACGGTTTTTAGGTTGTGTGTCCGGGGCTATGGGAACCTGTCCCCCATGATGGATCTT
GGTAGAGACACTTCCCTCTGTCATCGTGCCCAGGAGGATGCTGCAGGTGACTACCTGCAGCCCTGTTCTCATTCATTTGGATGCCCTCCA
GAAATCTGGGGAGCCATACACCTTTAGAGCCTTTTTTGCTCCTTATCAAGTTGGCAAGGCTTGGCCAATTCCTGTTCAAGGCTGCATTAA
AGGCATGTTCACCATCCTGGCTAATACGGTGAAACCCCTTCTCTACTAAAAATACAAAAAAATTAGCCGGGCTTGGTGGCGGGTGCCTGT
AGTCCCAGCTACTCCGGAGGCTGAGGCAGGGGAATGGTGTGAACCCAGGAGGCGGAGCTTGCAGTGAGCCGAGATCACACCACTGCACTC
CAGCCTGGGCTCAAAAAAGAAAAAAAAAAAAAAAAAAAGGCCCGTTCATTCTCAAATGCTTTTGGCGTCTCCAGGGTGCCTCAGGAAAAC
ATGAAGTGGGCATTGTAGAACTTGGGGCTACTGTGTAACTTTGGAAGAAAAAGTTAAGGGTACTTTTAAGTGGATACTGTTTTGATGAAA
TTGCCAACTTCAGGGAGCCCAGCTTGGAGAAGGAGGACGTGAGTATTCCTTACAAGGCTCCGAAACAATTCTTTCTTCACTTAGTTTTCT
TTCTGTGCTCTGCATCTTATATTCCAGCAGGGTCTTCCAATGCATGGTTTAATAACTACTAGAACTGGCCAGGTGCAGTGGCTCACGCCT
GTAATCCCAGAACTTTGGGAGGCTAAGACAGGCAGATCACTTGAGGCCAGGAGTTCGAGACCAGCCTGGACAACATGGTGATACCCAGTT
TCTACTAAAAATACAAAAATTAGTCGGGCATGGTGATGTGCACCTGTAGTCCCAGCTGCTCGGGAGGCTGAGGCAGGAGAATCGCTTGAA
CCCGGGAGACAGAGGTTGCAACGAGCCAAGATCGAGCCACTGCGCTCCGGCCTGGGTGACAGGAGACTCCATCTCAAAAAATAAAATTAA
AAAAAAACTACTACAATAAATTATCACCTTGGACTGTATAAAACAACTTTTAAACTAGTCTTTTTAAAAAGTACACTTAAATAAAAATCT
AAACATAAGAGAATGTAAAGTGAAAAGTGAAAGTATGTCTTCTGTTACGCAGAGGTAACTACTATTAGGAATCCTTCCTGAAAATGTCCA
TGCATCTACTCAGGTCATCACACCCATGGAATCATTTTACATACTATTTTATGAGTGTTACTTAATATACTGATCCACAGTGCGTTTTCA
CGGTCACGCCATCAGTTGTAGGAGTGTGCCAAGAACAGATGGGCCTTGCCTTTGTACCAGAGGAGTCCATTTACAGTTGCAGGTAATAGA
AAACCCAATTCAGACTGGCCTAAACAATGAGGGGAGGTTTTGGCTCTTGAAACTGGAAAGTCCCAAGGTGGGGTGAGTTTCAGGTTTGGG
TTGATCCAAGTGGCTCAGTGACGTCAACAGGATCTTGTTTCCATTTCTCTGCCTTCCACAGCCTCCCCTTCATCTATGGTGGAGGGAAGG
AGTCTACCACAGACAAACCCCGAGCCTCCCCCTGATGGGTGGTGTGGTGGTGAAGCCAGCAAGGGAAGGGATCCCCGGACACACCCCTCC
TCATGCTTTATCCCACTGAAACCATGCGGCTGTGAAATGCAGCATCCTCCAGGAGGGGGATGAAGGCCGGGGATGCTGTCAGCTATTGCC
ATTGCACTTCTGTGGATGGGTGTTACAGTTTTTTGCAGGGTTTTGCACTTACAAGGACATATATATATATATATAAACTACAGTGTTATT
GGAATTGCTTCTTACAGTTTGTAAGAAAAAAACATGTTTTTAGAGGAGTTCTCCTGGGAGGTGGGATCACATTTTTTTTTTTTTTTTTTT
TTGAGACGGAGTCTCGCTCTGTGGCCCAGGCGGGAGTGCAGTGGCGCAATCTCGGCTCACTGCAAGCTCCGCCTCCCGGGTTCACGCCAT
TCTCCTGCCTCAGCCTCCCGAGTAGCTGGGACTACAGGCGCCCGCCACTACGCCCGGCTAATTTTTTTTGTATTTTTAGTAGAGACGGGG
TTTCACCGTGTTAGCCAGGATGGGGGATCACATTTTAATAAGTAGGTACTCAGGGCTGGGGTGTACCTGTTGCTGCCTGACCACTGCTGG
TGTGTGTGGGTATAAGGTGACAAAACCTCCTACCCCTGTGAGGTTGTTTCAAGGATTAAATGAGTTGAGATGGGTAAGCATCTAACAAAG
ATCCAGATTATTTAGTATGCATCCCCTGAATTATTGCTAACATAATTTTAATGATTGGGGAATTTTATCTGTGGCTGCCAGTCCCTACGA
GAGAGCTGCCTGGGTCACATGTCAGATAGCTCAAGCTTTGAATCACTGAAACGAAACGGTCCACTTCCCTGTCCCTTTAGGAACAAGGCT
TCGAGGTCTGTGGCAAGCCTCAGCAGGCATTTGGAGTTCAAGGTCTGTTCTCTTTCTGTGCCATAGAGGTGGGGAGACAAGGTAGGGTGT
TGCTTCTTGCCTGGAGCGCAGATGCTACCAGAAACCAACACAACCAAAGTTGCCCGGGAGCCCCCAGAAGCAGCAGAGTGGCCATCAACT
GCCAAGGGGCCAGGGTAGGCCACAGAGGCCTGGGGCCCAGGAGGGATGGTCTGTGGGGAGAAAGGGGATTATTGTGAACATCAACGCTGG
GGATAATGTGCCCTGAAGACAGCAGCATATCACGTTTGGACGGTTGGTGGACCCCATCTGGTCCCACTCATAAGGAGAACAGAGGCCCTG
GGGTGTGCTGGGACTTGCCTGAGGCCTCAGACCGGGACTGGGTGCTCCTCCGCACCTCCTATGAGGGAGGGTGTCCGTGTCTGTGAGGAC
AGCTCAGCAGGGCTGGGAACCTGGGGGCAGTGCTGGGGGACATGTGTGAGACTAGCGTGTGTGGGCCTTGCTCGGCTTGCCCTGGTGCCC
TGAGAAAAACCTGGTATTTGAAAATACACATGGACTGCTGGAAGGTCAGGAAATCCAGGGTTTTGTTCTGAGGCAGTGGAAGTGTTACCG
TGAGCCTGTGTTGGCCTCTCTCCTCACTCCACCTGCAGCCAATTCAGCCACACTGCCTTTGCATGGAACCCAGGGTTGCAGGCCGCGTGT
GTAGATGCTGATTTAGGCCCAAGCACTCAGCTGTCAGCAGGAAGGACCATAGTGTTTTCTTCTAGTTTTAGATATGCACTCGTTCTGTGT
TTTAAAGTCACAGCTGTGAGCCAATATGGGAAGAAGTGAAGTGGCCTCTAGGAGGGACTGAGCACCCTGTCCTTGGAGGTATGCAAGCCC
AGGCTACACCCTTCCTGTCTGGGATGATATGGCTGGGGGTGGGCTTTGTGCTGCGTGGACCATGGCAAGCCTTTCCATCTCTGAGAGGTA
GTGGTCCTTCCCGTGCCTTCTGTTAAAGATAATTTTTTAAAAAAAGGCATAACTCATATATATTACATGTACACATGTCAAAGATTTTAT
TTAACTCAGTAATTGAGAGTGCTGCTAAGATTAACAGCCAGTTCAAAAGAGAAATCACAATGAACCATAAATCTGTATGGAGTAAAGGAA
AGTTGAAACTGGCTGGGGTTTTTTTTTTTTTTTTTTTTTTTGAGGAGAAAGGTCAATTGAATCTTATTCGTATAATATGCACATCCATAG
ACAAGAATTATTTTGCATTAACTCTACAACTTAGTTGTAAAAATAGCTCAAAGGCAGTGAAAGACTAGAATCAGATAATTGGAAGGGTGC
ACCCTAAGCAATGCATAGTTCTATTTTCTTTCTTTTTTTTTTTGAGACAGAGTTTCCCTCTTGTCACACAGGCTGGAGCGCAGTGGTGCA
ATCTTGGCTCATTGCAACCTCTGCCTCCCGGGTTCAAGTGATTCTCCTGACTCAGCCTCCTGAGTAGCTGGGATTACAGGCGCATGCCAC
CACAACTGGCTAATTTTTGTATTTTTAGTAGATACAGGGTTTCACTGTGTTGGCCAGGTTGGTCTCATACTCCTGACCTCAGGTGATCCA
CCCGCCTCGGCCTCCCAAAATGTTGGGATTACAGGCGTCAGCCACCACGCCCGGCCCCAATGCATAGTTTTTTACTGAAGACAACCAGAA
TCTCTGTTGCTTATTCCAAATTTCCTTCCACCACTTGTCCATCCAGCAGAGCCACTTTTAAAATAGGACACAGGCAGAAATTTAAAGGAG
TCAATATCTCATGGTGAAAAGTGAATCCTGAGGGTTAGAGCATCCACCAGGTGCCCTAGGTAAGGGCCAGCCACTCTGGGAGGCAGCCCG
GGGCACTCACTGTCCTCTCAGTAGTAAATGAAATCACTCAGGCCATGTCTGCTACCCAGAGAGCCTGAGTGTCCTCAAATGCTTGTTCTG
CCTCTCCATCCACTCCTGCAGACACCTCAGTGGCTGCATCCCAAACCGCTGAACTTTGCTTCTCTTTCTCCAACCCCCAATTCCACCCAC
ATCCAAAACTGCTCTGCCCCCTATTCCCATCTCAGCTGAGGGTACTATCATCCACCCTGTGGCCACATCCAGGAATGTGTGTATCACCTG
GGCTCTGAGGATGACATCAGCTCTTCTAAGTCAACAGAATGTCGGGTCTGTTCTAAAAGTCTCATCTGACAAGGAGATCTTTAAGGCTTT
ACTCCCTTAAAGGCTTTACTCCCATCATGATGGGATAACCATCATGATGGATTTCAGTGTCATTCTGTCTTTTTCTTCGGAATGATTCCT
GGGACTCGCCTTGTTTGCAACATGTGCATTGAAATATCTTTTCAACATAACTTTGTTCTTAATTGTGTTTACTTCCTTTCTCTGTGAATC
TCAGTGATTCCTGGAAGCTGTGGTTGGTGGGGGATGGGGTGGGAGGACTTTGGTAGTATAAAAGAGTACCTGCAATGAATGTTCTAAGAA
ACTGGAGTGTTGGGGTCCTCCAGCCCTTGGCTGGTAAACTCTCCACTCCTTCCTCTTTGCAACACAATTCTCATAACTGGCAAAGGTGTG
CATGTAAAATTTGTGACTGTAGTCTGAGGTTTTTTTTCCCTGTACAATTCCGCCTTCCCCCCTGTAAGCCTGTACCAGGAGAGGTCTCAG
CTGCCTTGGAGGCGGTGAGACACGTGGGTGCTCACTGTGGCCCTCAAGGGTGAGGCTGGCACTGGGGCATCTGGGGCCAGAAGTCCTCCT
TTAGTCCCAAGTCTCTGCCACTCAAGTGCATCAGTGAGAGGTCCTCATAGAAAATCTACTGTGGGCACAAAGCTGCCAGGCTGATGGGGG
TGGGGAGCAAACGAACACCCTTTTCCCCTTTTACACCAGAGGAAAGAGACTTAGACTGAGGAACTTGCCTGCTGCCAGACAGCTGGGAGG
TGGTAGAACCGGGCTTACAGCCCAGGGTTTCCACTCTAGGAACTCTTCTCCCTTCCTCTGATGACACTAACTCGCAGGCCATGATCAATG
AGCAACGATGTAGGCAGGCACTGACGAGGCACAGCAGGAAGGCAGCTCAGTGCCCATGACGGCCAGGAACTGGGTACCATTTCCTCAGCA
AAATGGGATAGTAACTCCCACACTGCAGCTACGCACTTGGGCAGTGGTTCACAAGGCCAGCAGCCACAACATCACCCCAGACCAGCAGCA
GCTGCAGCATTACCCCCAGCACTTGTTAAAAGATGCAAATTCAGGCCAGGTGTGGTGGCTCGTGCCTGTAATCCCAGTACTTTGGGAAGC
CAAGGCGGGTGGGTCACCTGAGGTCAGGAGTTCGAGACCAGCCTGGCCAATGTGGTGAAACCCTGTCTCTACTAAAAATACAAAAAATGA
CCCGGGCATGGTTGTGGGCGCCTGTAATCCCAGCTACCCAGGAGACCGAGGCAGGAGAATCACTTGAACCCGGGAGGCAGAGGTTGCAGT
CAGCCGAGATTGTGCCATTACACTCCAGCCTGGGCAACAAGAGCGAAACTCTGTTTCAATAAATAAATAAAAATGCAAATTGTATGCCCC
TTCCTTCAGGCCTATGGGACCAAAAACTGGGATGGGGCCCAATAAAATGTTTTAACCAGCCCTTCGGTGGTTACAGAAGGATAGAGCCAG
AATAGACTAACCACTGTAACAAACATTACCTATACTTGGGAGGCTTTGAAAAATGTTTATTTAGCCGGGTGCGGTGGCTCACGCCTGTAA
TCCCAACACTTTGGGAGGCTGAGGCGGGCGGATCACGAGGTCAGGAGATTGAGACCAGCCTGGCTAACACAGTGAAACCCCGTCTCTACT
AAAAATACAAAAAATTAGCCAGGTGTGGTGGCAGGTGCCTGTAGTCCCAGCTACTCTGGAGGCTGAGGCAGTAGAATTTCTTGAACCCAG
GAGGCGGGGCTTGCAGTAAGTCGAGATCACGCCACTGCACTCCAGCCTGGGTGACAGAGTGAGACTCCATCTCAAAAAAAAAAAAAAAGG
AAAGAAAAATGTTTATTTTTTTGCTCATGCCACAGTCTCTGGTAGTTGCTGGGAACTAGGGTGGGGGATTCTCTGCTCCACACAGTCTTT
CATGGACCCAGGTTCCTTTCCTGTTGTGGGTCCAGCCTCCTGTAGCTGTTGGAGGCATCTCTAGTCAGCTGGTGGTTGGGGAAGAGGTGA
GGATCAGGGAGGGAAGATGGAGAGTACTCTGCTTGTTCTCACATTCTGCTGGCCAGAACTCACAAGCCACCTGAAATGATGCAAAGGTCT
AGCTGTGTGTGTAGGAGAAAGAAGAGAGGCCAGATATTGGAAGACAGCAGTGGTCTGTGCCCCAGGCCCCATGGTTTAGGGAAGTGAACC
TTGGCACTGGATTTCCTGGCTTTCTAAATCTCCCTTTATAGGGAACTTAGGGCCCAGTCTGTGGTGGGTGGATTTGCCTGGTTCACAGCC
TCTGGTCAGCCTTCTTTCTGCTCCACAGGGCGGCCTGGAGATGGTGGGCTCCTTGTCACACTGGTTGGGGATGTGGGCTCCATGGGGCCA
GAGATGTGTGTGCTCTGTGTTCAGATTAAGGGACAGACGGCACATGAATTCCTTCAGTGCCCTCCAGATTTGGTCACTGGGGAGGGGTAG
GCTGAGCAGTAGCTCTTGGGTCTGTAGTAGTGTGACCCTGGAAGGACTGTCCAGCTGAAAACAAGAGCCTGGGGCGTGGGGAGGGGAGGG
GTTACTCAGGGTTCCATGAGACCTGGGTTTAAGTCCTGGATCCATCATTAGCAGCTATGTGAACTTATGCCTCACTTTCCTCAAATATGA
ACTTGAGATAATGAAATTACCTTCCTCATAATACTGTTCTAAGAATTGAATGAGGAAAGGTTTACAATTCGGCCCTGGTTGTTCCACTGG
GGAGGGAACAGAGATTGGGGGCACAGGGCTCCCCTGGCCTGGGGGAGTCTGGCTCACTCAAGTTCTCAGTCATTTGCAAGGCAAGGACCC
TGCTTCTCCTTGCTCTGGGTCCGAGTAGTCTCAAGCCCAGTGGGCAGGGCCTGTGGTGTGGATGGACTCGTCTGCAGTGAGTCAGGCAGC
AGGCAGAGCTGGCAGGCTGTGTGGTCTCTAGTGGGTACCAGGGGACCTGGGAGGGCCTTGTGGGAGGTTGTCCACGGTGTGAGCCAGTTT
GCCATCTGGGGTCCTGGAGTTCCCTCCCGCCCTTTGAGTTAAAAAGAGTCAGTCCTGGGCTGAGACTTAATTGCGCTAGTGCTGAGTGAC
CTTGTGTCAGGGGAAATCGGATGGGGCAAAGTGTTTTTTAATTAGCAGGACTCACTGACCTTTCCTTCACTGTCAGCAACTTCTCACAGG
GAGGCAGAGCAAGGGGGGCTGGAGCCCCGCATCTCTCTAATGGAGCCTATGTCCAACAAGGAGGTGGATGGCTGGATTCAGGGCCCTGGG
AGGACTTCATGTGGGAAGCAGACCTCAGGAAGGGCCCTTAGTGATGGTGTGGGCCAGGGTTCTCACCTCCTTAGTCTCCTGTCCTGTCCA
TCTCCGCAGATCCTAGGCAAAAGAAGCGGAGAAACACTCAAGCCACTGGGGTGGTTAGGGCACACTGGTGGCAACTGTTTAAAACCTTAA
CTAAAACAAGGTTAAGCAAAAGGAGTTTACAGGCTCTCATAGATGGGAAGGATGTGGGAGGGTCACAGACTGAGAGGAACCAGGGCTGTG
GCTGCTGGAAGGAGCCTCACCACCGCCAGTGTGTTTCCTCCCCGTCGTCGGCATCTCTGCTTCTCTCTGCACGCCAGCAGCTCTCTCTTA
GGGCACGCAGACCTTTCCTCTGCAGGGGAACACGAGTGCCGGCAGCCCCGAGTTAGTGACTATCATAGAAACTCAGTGTATTTCTCTCTT
GTTTATCATTCCGAGTCCTGAGTCACAGGCTTGTCCAGCACTCAAGACTTTTTCTTTTCTCTATTTTTTGAAACGGATTCTCGCTCTGTC
CCCCAGGCTGGAGTGCAGTGGCCCGATTTTGGGTGCAAGCGATTCTCCTGCCTCAACCTCCCGAGTAGCTGGGACTACAGGTGTGCGCCA
CCACATCCAGCTAATTTTTGTATTTTTAGTAGAGACGGAGTTTCACTATGTTGGCCAGGCTGGTTTCAAACTCCTGACCTCCCGCCGGCC
TCAGCCTCCCAAAGTGCTGGGATTACAGGCATGAGCCACCACGCCTGGCCAAGATTTTTTCTTTTAAACCTGGAGTATGGAGATGCTCAC
TAGGCAGACAGAATCAGCCACCACAGCCCACTCCCTCAGCCAGTATTACTTTGACTAAGTTAGTGAGGAACCAGGCCCCAGATTAAGAAG
CAGAACTCACACTGTCATCTGCTGTGTGCCTGGCTGGCTCATGCATACCTTGTCTATCTAATGTGGACCAAAGCCCTGTGGCACACCCTG
CTGGTTACCCCCAGTGGTTACCCTGGCACAGAGGAGGAAAGGGAGTCGTGGGAGGGAGAAGGACTTCCCTGGGAGGTCTCTGGGCTGGCA
AGTTGGGTGACACAGGTCCGGTTGGCTGCAAGCCTGGGCTCTGCTGTTGTAATCATAAATGTGTGTGTGTGTACAGTTGTTTACAATGTC
AGCATGGGTGTCCTTGTTTGTTAGAGATACATGCCACTGCTCCCATCATGAGGAAAATCCCAAGCCCTCCCCATGATTTTTGCCAGTTTC
TGGGGACTCATGCTCCTGGCAGCCCATGTGTCCCCAACTCCTGTGTCCTTTAGGGACCTCTGTTGAGCCCTGCCTCTATTCTGGCAGAAT
TAGAGAAAATTCTTTAAAAAAACAATAAAGTTTAAATTCATTTAAAAAAATAATAAAAAATCTCACAGCATGAGTTTTGATGAGATTTGG
GGCAAGGTGGGCCACAACCTTGGGTTGTATGGCCACCTCCCCCTCTTCTTCCCCTGTTGTCTCTGCAGCTCAGAAACCCCAATTTCCTGG
CCTGTGTTATGTGGAGGAGCTGAGCTCACCCCCTACAGCTTCATCTCCAAACCTAGCAAGGATCCTGCCCAGATCAGGAGATCCTCCTTT
TAACAGAAGTTATTTACACTCCTTAGAAAGCAGTGGGGGTGGAACGATTCTTTTTCCTGATGCAGAGATGTAAAACTGGGACATTGCTAC
ACATAATATTTTAAACCTGTCTTCCCTCTTACCAACGAACACATCACTAGCACCATCTATGCCAATACATTTCTCAACATCAATTTCAGT
GGCTGTATTACATTTTATCCTACGGATGTGCTCTCATTTATAATCTAAACCACTTTTATTGAACACATCAGTTATTCTGAAATTTTCAGT
GTTATGATGGATGTTGCAGTAATTATTCTTATATATGCACAGAACCCCCAGAGGACATGACTACTGAAGGCTGTGCTGGCAGGATCACAG
GTAAGGATCTAGCAAATTGTCCCAGCTTCATTGACTGAGCTTTCATCCTTGTTGCACTACTTTGAGCTGCCATTTTGATCATATAATAAT
GATTTAGTAGAGCTCTTTTTTGGTTCAACCTACCTGTTCTTGTATCAGAACTGAAATGTTTGATTTTATAAATTTGAATAGTGGCACAAT
ATAGAGTTCACTATTCCTCAATATTTTCAAGGCTGTTTCTTATCTGTTCATTCTTTTGGTTAACTTGGGAATTATTTTATCAAGTCTCTC
TACTTCCCAATTTCCTTTCACCTTTGGCTCGAAATGATATTCAATGTATACATTAACTTGAGTTACATTTTGCTGCATAATGCTTGAGTT
ACATTTTGAGTATTACGTGTTACTCATAATACATATTGAGTTACATTTTGCTGCATAATACATTATCCCCAAGTTTAACACCTTAAAGCA
GCACATATATATCTCATACCCTTCTGAGGGTCAGGAATCTAGAAGCAGCTTAGCTGGGTGACTGTGGCTCTGGGTCTCTCATGAGGCTGC
AGTGAAACTGTTGGCCAGGGCTGGAGGATCCCTTCCAACCTCACTCCATGACTGTTGGTGGGAGGCTTCAGTTCTCCACCTGGTTCTCAC
AATATAATTTCCCCCAGAGTGAGTTATCAGAGAGAGTGTGCAACCAGTAATCTGTTAGAATATGTCACGTCTGTCATATTTGATTGGTCA
CTCAGACCAACCCTAATAGATGCGAGAGTGACTATGCAAGGGTGTGAGTTCCAGGAGGAAAGCATCATTGGAACCATCTTGGAGACTGGC
TAATACACAGATAAATGGCACATCTGACAATATGGCATCTTTCTGAGTGTCAGTGTGGTGTGTTCCTATATGAACTTAATGCTATTAAAC
TTAATTAAATTGTAGGTATGCTCTCAGTGAAGATTTTTACTTTTACATTACAGGTTTCCACACTGTTAAATTCATTCCAAGTATTTCATA
CATGCTGTTCCTATTATGAAAGGATCTTTTTTTTCACATGGCATTTTCTAAGTAGTTGTTGCATTCATATAGGAGATGCTATTGATTTTG
ACACCCATAATTTTTCAGTGGAGACAAGGCAGAAACTACTCCAGACTCTCACCTGCTGTTGCTGATCCTTACATGGTGGCTGTGCCAGGC
TCAGCCGCGCTGAGATGACAGGGCTGTCTGGCCATCATTGGTCATATGGACTTCAGATTTGAAAGGATTTTATGTAGAAGCAGAGTGCCT
GATAGGACTCTCCGGGACCCCCATTTCTGCCCTGCTTGGCTCCCACTGGCAAGGCTGGCTCAGTTCCTGTCACCTTCTCCTGGACTTTGG
CCAGAGTCCACTGGCTGTTTCCCCTGCCTCCTGCTCTCCCAGTGCCCTCTCCACACCAGTGCCAGAGCTGCTTCTAAGAGATGCCTCAAA
GCCCGCTTCCAGCTTAGGAACCCCAGGGAACATGGATGGTTTCTCCATTGCCACTTCCTAGCCTTCCTGGCATAGGAAGGTCTGGTTTGC
CTGCAGGTCCCTCTCTGGGGGGGTCCCTGCTCCATAGATGCTGAGGCTCCAGAAGTCTGTTCTTTTATATCACATTTGAAAACCTTTGAA

>55722_55722_1_MTMR10-TSPAN14_MTMR10_chr15_31266517_ENST00000425768_TSPAN14_chr10_82264482_ENST00000429989_length(amino acids)=401AA_BP=158
MFSLKPPKPTFRSYLLPPPQTDDKINSEPKIKKLEPVLLPGEIVVNEVNFVRKCIATDTSQYDLWGKLICSNFKISFITDDPMPLQKFHY
RNLLLGEHDVPLTCIEQIVTVNDHKRKQKVLGPNQKLKFNPTELIIYCKDFRIVRFRFDESGPESAKKLAGVVFLGVGLWAWSEKGVLSD
LTKVTRMHGIDPVVLVLMVGVVMFTLGFAGCVGALRENICLLNFFCGTIVLIFFLELAVAVLAFLFQDWVRDRFREFFESNIKSYRDDID
LQNLIDSLQKANQCCGAYGPEDWDLNVYFNCSGASYSREKCGVPFSCCVPDPAQKVVNTQCGYDVRIQLKSKWDESIFTKGCIQALESWL

--------------------------------------------------------------
>55722_55722_2_MTMR10-TSPAN14_MTMR10_chr15_31266517_ENST00000435680_TSPAN14_chr10_82264482_ENST00000429989_length(transcript)=16451nt_BP=572nt
AGAAAGGGCCTGGGCGGCCGCACTGAGAGCTTTACGCCCGGAGGCGTCGGCGCTGCCACTGGCCCGCGACGGGAACGGGGCGAAAAGGCG
GCGGCACCATGTTCTCCCTCAAGCCGCCCAAACCCACCTTCAGGTCCTACCTCCTGCCACCGCCCCAGACTGACGATAAGATCAATTCGG
AACCGAAGATTAAAAAACTGGAGCCAGTCCTTTTGCCAGGAGAAATTGTCGTAAATGAAGTCAATTTTGTGAGAAAATGCATTGCAACAG
ACACAAGCCAGTACGATTTGTGGGGAAAGCTGATATGCAGTAACTTCAAAATCTCCTTTATTACAGATGACCCAATGCCATTACAGAAAT
TCCATTACAGAAACCTTCTTCTTGGTGAACACGATGTCCCTTTAACATGTATTGAGCAAATTGTCACAGTAAACGACCACAAGAGGAAGC
AGAAAGTCCTAGGCCCCAACCAGAAACTGAAATTTAATCCAACAGAGTTAATTATTTATTGTAAAGATTTCAGAATTGTCAGATTTCGCT
TTGATGAATCAGGTCCCGAAAGTGCTAAAAAGTTGGCTGGAGTTGTCTTCCTTGGAGTCGGGCTGTGGGCATGGAGCGAAAAGGGTGTGC
TGTCCGACCTCACCAAAGTGACCCGGATGCATGGAATCGACCCTGTGGTGCTGGTCCTGATGGTGGGCGTGGTGATGTTCACCCTGGGGT
TCGCCGGCTGCGTGGGGGCTCTGCGGGAGAATATCTGCTTGCTCAACTTTTTCTGTGGCACCATCGTGCTCATCTTCTTCCTGGAGCTGG
CTGTGGCCGTGCTGGCCTTCCTGTTCCAGGACTGGGTGAGGGACCGGTTCCGGGAGTTCTTCGAGAGCAACATCAAGTCCTACCGGGACG
ATATCGATCTGCAAAACCTCATCGACTCCCTTCAGAAAGCTAACCAGTGCTGTGGCGCATATGGCCCTGAAGACTGGGACCTCAACGTCT
ACTTCAATTGCAGCGGTGCCAGCTACAGCCGAGAGAAGTGCGGGGTCCCCTTCTCCTGCTGCGTGCCAGATCCTGCGCAAAAAGTTGTGA
ACACACAGTGTGGATATGATGTCAGGATTCAGCTGAAGAGCAAGTGGGATGAGTCCATCTTCACGAAAGGCTGCATCCAGGCGCTGGAAA
GCTGGCTCCCGCGGAACATTTACATTGTGGCTGGCGTCTTCATCGCCATCTCGCTGTTGCAGATATTTGGCATCTTCCTGGCAAGGACGC
TGATCTCAGACATCGAGGCAGTGAAGGCCGGCCATCACTTCTGAGGAGCAGAGTTGAGGGAGCCGAGCTGAGCCACGCTGGGAGGCCAGA
GCCTTTCTCTGCCATCAGCCCTACGTCCAGAGGGAGAGGAGCCGACACCCCCAGAGCCAGTGCCCCATCTTAAGCATCAGCGTGACGTGA
CCTCTCTGTTTCTGCTTGCTGGTGCTGAAGACCAAGGGTCCCCCTTGTTACCTGCCCAAACTTGTGACTGCATCCCTCTGGAGTCTACCC
AGAGACAGAGAATGTGTCTTTATGTGGGAGTGGTGACTCTGAAAGACAGAGAGGGCTCCTGTGGCTGCCAGGAGGGCTTGACTCAGACCC
CCTGCAGCTCAAGCATGTCTGCAGGACACCCTGGTCCCCTCTCCACTGGCATCCAGACATCTGCTTTGGGTCATCCACATCTGTGGGTGG
GCCGTGGGTAGAGGGACCCACAGGCGTGGACAGGGCATCTCTCTCCATCAAGCAAAGCAGCATGGGGGCCTGCCCGTAACGGGAGGCGGA
CGTGGCCCCGCTGGGCCTCTGAGTGCCAGCGCAGTCTGCTGGGACATGCACATATCAGGGGTTGTTTGCAGGATCCTCAGCCATGTTCAA
GTGAAGTAAGCCTGAGCCAGTGCGTGGACTGGTGCCACGGGAGTGCCTTGTCCACTGTCCCCCTGTGTCCACCAGCTATTCTCCTGGCGC
CGGAACTGCCTCTGGTCTTGATAGCATTAAGCCCTGATGGCGCCGGTGGCGCGGTGGGCATGGTTCTTCACTGAGAGCCGGCTCTCCTTT
TCTTAAAGTGTGTAAATAGTTTATTTATAGGGGTAAGAATGTTCTCACACCATTTCACTTCCTCTTCCTCTCCTCCAGCATTCTCCTCTG
AGCAGCCTTAGATAGTGTCCATGGCTGGAGCCGACCCTTTGAGTCCCCTTGAGTGTCTTAAGAACCAGCCCACAACAGCCTCTCTTTCTC
CTCCACATACTGCAGCCTCCCTCCATGCATCCCACATACAAGCACTCCCCCACTCCCCAGCGTGGCCTCACTGTCTTCTGGTCTTGGTGC
TACTGAAATTGTCACCCAGAATTTGAATCCTGACCCTCCCCACTGCAAGCCCAGGGAGCCCCAGCCCAAGATGGCCAGCCTGAAACTGTT
GGCCAGGGCTCCTCTTGTGGCCATGTACCCAGGGCTGGCTGGCCTGCCATTTGCCTCTCCCCGGAGACAGCCGTTCTTCTGCAACCACAC
CCCGTGCCTAGCCACAACCCCAGGCTGCAGCTGCTCAGAAGCTCCAGGCATTTTGTTTCTGGTGACCGCCCCTAATGGGATATCGGTGAT
CACTGGTCCACCCTTCCTGTCAGGGCTTTTCTGGGGCTGCTCTTGGAAATGAAGTCTTAAGTACTGAATAACTCCCCTGGGGATAGCTGG
GGCATTTGTCTAGCTGGGCTACTTTCTAACACTTTGCCATAGCTCAGACCACTTCTCATCGTTCAGGGATGGACTGCAACCTTAATTTAC
TTGCCGGAGTGTACATTCTAGTGTGGTGTATACTGGTGGCTGTTGATGATGATTTTTTTTTTTTTACACAATTCTCTGTAGACTAGGAGA
AGAATGCTTGTGTTTTTCGGAAGTGTGATGCTTCTCTTTGACTGCCAAACTCTTTTATGGAATATATCTTTATATTAATGCTGTTTTGGT
CATTTTTGTTTGGGGTCACTATTGAGATATTGCTAAGCATCTCAGTGGTAAACGCGGCTGCCAGAGGAACCAAGGGATAGGGTATGTAGA
CCTTACAGAAGGATGGATGGTAAAGGCAGTCCATCATCAGCACAATCTGACTTACATTTCATTGAGTAATTTTTTTTTTTTTTAAGATTC
TGTATGGCAGCACTTTCAGTTGCCCTTGTGTGCCGGCCACAGCCGCACAAGTTGGCTTGTGGTTTATCCCCCGCTATAAGTGAGAGCTGG
AGAAACTTCAACTCCATAGGTCTAGAGGAAACATTGTTTTAGGTTATTTCTGTCCACCCCTGTGCGATACTATTTATTGATCCAAGCAGA
AGAGCTTGGGGACACTGAGTCGAAGTGGGGACATGGGATTGAAGCCTGGGCACTGCTGCTGCATGAGCTGTGTGTCCTGGGTGTGCCGGC
CTTTCTGTGAAGGGGGTTGGTGGCAGTGCCCACCTCACTAGATGCCTCTGACCCAGCCTCCCCTGGGGGAGTGGGTGGCCACAGACCCTC
CCTGCCAGAGCTCCTGGAAGGCTCCTGCAGGCCTGACCCATCTATTCCTGTAGACCTGGTTTAGGATGAAGTCTCGGTGCGATTTTTGCA
GAGTTGGGTTTATCTTTCAACTATAGACCCTTCTGGCTGTTCTCAGCCATATCATGTGACTCTGAATAGTTGGATGAGGAATGGAAAGAA
AGCAAGGATGAGAGCCGGTCACGTGGCAGTCTCCGCCCAGCATCGGCTGTCCGCACAGAGGCACAGGGCAGGCCTCCTGTGCACTCCCCA
CCTAGCACTGGCCTGTCCTGAATCCCCGCCTTCCCTGGTTGGAGGCCAGCTGTGGCATTTGCACCCTCTTCTCACCTCACCATGCACATG
CTAACTTTAAAGCCTTGGGGTCTTTCCTGTACCCCCTCCTCAACCCTGGTCCACCCCCTCTCAGGATCTTGTCAACGTTATTTTTCCTGT
CCCGTCTTCCTATCGCTGGCCTTCCTTTCCCATCCTAAAAACTTGCCGAGGCCCTATGGCTCCCTCCCTTTCTTTCCCAGGCAGCTTCTT
ATCTGGGCTGTCTGTACCCCTTCCTTTGCACCACCCACCATGCCCCACGTAGCTGAAAGCTGCTTATCCCAATTGTCAACTCTGGCCTTC
TTCAGCCTCTGTAGCACCAGACACTGCACCTCCTGAATGTCCTCTGCTTCTCTGCTTCAGAGGCCCAGGCTCGCCAGTTCTCTGACCTCT
CCCATATGTCTGCTTAGGACTCTGCTGCAGCTGTCCTCACCAGCCTCCGGGGAATCCCACTACCCACAGGGCAGGGCTGTGGGCTGGGCT
GAAAAACCATCTGCATGGTCCACAAGAAGCCTGGCACTGGGTTTCCCCATGAATAACAATGAAAATTAATGGATGCACAACCTTCCTGGA
ACGTGGAATTTCTCTGGGAGATTCCATGCAGAGGCCACTGGGGAGGTGGCAGGCATGCATGTGACTGTAGGTGGCTGCAGTGTTGGAAGG
CTCCCAGCAGAGCAGAGAGGGTGTCAGTCTCATCAGGGAACCCACCTGATGGCTTCTCAGCCAGCAGTCTCAGAGGAACATAGACGACTG
CTGAGAAAGGAGGGAGGCAGCAGTGGTCCCAGCACCTGAGGCATCCTGCTGTCATGGGAAGGTCTCCGCCCAAATGTCAGATGCATCAGC
CTGTCACCCGCTGGTCCAGAGCTTTCAGCTGTACTGGTAGGGGGTGGGTGGTGGAGTGCTGAATGACCTTCACAGGTGGGCCTTTCCAGC
TCTAGGGTCTTACGGGTGTCGGTCCACAGAACCACGGTTTTTAGGTTGTGTGTCCGGGGCTATGGGAACCTGTCCCCCATGATGGATCTT
GGTAGAGACACTTCCCTCTGTCATCGTGCCCAGGAGGATGCTGCAGGTGACTACCTGCAGCCCTGTTCTCATTCATTTGGATGCCCTCCA
GAAATCTGGGGAGCCATACACCTTTAGAGCCTTTTTTGCTCCTTATCAAGTTGGCAAGGCTTGGCCAATTCCTGTTCAAGGCTGCATTAA
AGGCATGTTCACCATCCTGGCTAATACGGTGAAACCCCTTCTCTACTAAAAATACAAAAAAATTAGCCGGGCTTGGTGGCGGGTGCCTGT
AGTCCCAGCTACTCCGGAGGCTGAGGCAGGGGAATGGTGTGAACCCAGGAGGCGGAGCTTGCAGTGAGCCGAGATCACACCACTGCACTC
CAGCCTGGGCTCAAAAAAGAAAAAAAAAAAAAAAAAAAGGCCCGTTCATTCTCAAATGCTTTTGGCGTCTCCAGGGTGCCTCAGGAAAAC
ATGAAGTGGGCATTGTAGAACTTGGGGCTACTGTGTAACTTTGGAAGAAAAAGTTAAGGGTACTTTTAAGTGGATACTGTTTTGATGAAA
TTGCCAACTTCAGGGAGCCCAGCTTGGAGAAGGAGGACGTGAGTATTCCTTACAAGGCTCCGAAACAATTCTTTCTTCACTTAGTTTTCT
TTCTGTGCTCTGCATCTTATATTCCAGCAGGGTCTTCCAATGCATGGTTTAATAACTACTAGAACTGGCCAGGTGCAGTGGCTCACGCCT
GTAATCCCAGAACTTTGGGAGGCTAAGACAGGCAGATCACTTGAGGCCAGGAGTTCGAGACCAGCCTGGACAACATGGTGATACCCAGTT
TCTACTAAAAATACAAAAATTAGTCGGGCATGGTGATGTGCACCTGTAGTCCCAGCTGCTCGGGAGGCTGAGGCAGGAGAATCGCTTGAA
CCCGGGAGACAGAGGTTGCAACGAGCCAAGATCGAGCCACTGCGCTCCGGCCTGGGTGACAGGAGACTCCATCTCAAAAAATAAAATTAA
AAAAAAACTACTACAATAAATTATCACCTTGGACTGTATAAAACAACTTTTAAACTAGTCTTTTTAAAAAGTACACTTAAATAAAAATCT
AAACATAAGAGAATGTAAAGTGAAAAGTGAAAGTATGTCTTCTGTTACGCAGAGGTAACTACTATTAGGAATCCTTCCTGAAAATGTCCA
TGCATCTACTCAGGTCATCACACCCATGGAATCATTTTACATACTATTTTATGAGTGTTACTTAATATACTGATCCACAGTGCGTTTTCA
CGGTCACGCCATCAGTTGTAGGAGTGTGCCAAGAACAGATGGGCCTTGCCTTTGTACCAGAGGAGTCCATTTACAGTTGCAGGTAATAGA
AAACCCAATTCAGACTGGCCTAAACAATGAGGGGAGGTTTTGGCTCTTGAAACTGGAAAGTCCCAAGGTGGGGTGAGTTTCAGGTTTGGG
TTGATCCAAGTGGCTCAGTGACGTCAACAGGATCTTGTTTCCATTTCTCTGCCTTCCACAGCCTCCCCTTCATCTATGGTGGAGGGAAGG
AGTCTACCACAGACAAACCCCGAGCCTCCCCCTGATGGGTGGTGTGGTGGTGAAGCCAGCAAGGGAAGGGATCCCCGGACACACCCCTCC
TCATGCTTTATCCCACTGAAACCATGCGGCTGTGAAATGCAGCATCCTCCAGGAGGGGGATGAAGGCCGGGGATGCTGTCAGCTATTGCC
ATTGCACTTCTGTGGATGGGTGTTACAGTTTTTTGCAGGGTTTTGCACTTACAAGGACATATATATATATATATAAACTACAGTGTTATT
GGAATTGCTTCTTACAGTTTGTAAGAAAAAAACATGTTTTTAGAGGAGTTCTCCTGGGAGGTGGGATCACATTTTTTTTTTTTTTTTTTT
TTGAGACGGAGTCTCGCTCTGTGGCCCAGGCGGGAGTGCAGTGGCGCAATCTCGGCTCACTGCAAGCTCCGCCTCCCGGGTTCACGCCAT
TCTCCTGCCTCAGCCTCCCGAGTAGCTGGGACTACAGGCGCCCGCCACTACGCCCGGCTAATTTTTTTTGTATTTTTAGTAGAGACGGGG
TTTCACCGTGTTAGCCAGGATGGGGGATCACATTTTAATAAGTAGGTACTCAGGGCTGGGGTGTACCTGTTGCTGCCTGACCACTGCTGG
TGTGTGTGGGTATAAGGTGACAAAACCTCCTACCCCTGTGAGGTTGTTTCAAGGATTAAATGAGTTGAGATGGGTAAGCATCTAACAAAG
ATCCAGATTATTTAGTATGCATCCCCTGAATTATTGCTAACATAATTTTAATGATTGGGGAATTTTATCTGTGGCTGCCAGTCCCTACGA
GAGAGCTGCCTGGGTCACATGTCAGATAGCTCAAGCTTTGAATCACTGAAACGAAACGGTCCACTTCCCTGTCCCTTTAGGAACAAGGCT
TCGAGGTCTGTGGCAAGCCTCAGCAGGCATTTGGAGTTCAAGGTCTGTTCTCTTTCTGTGCCATAGAGGTGGGGAGACAAGGTAGGGTGT
TGCTTCTTGCCTGGAGCGCAGATGCTACCAGAAACCAACACAACCAAAGTTGCCCGGGAGCCCCCAGAAGCAGCAGAGTGGCCATCAACT
GCCAAGGGGCCAGGGTAGGCCACAGAGGCCTGGGGCCCAGGAGGGATGGTCTGTGGGGAGAAAGGGGATTATTGTGAACATCAACGCTGG
GGATAATGTGCCCTGAAGACAGCAGCATATCACGTTTGGACGGTTGGTGGACCCCATCTGGTCCCACTCATAAGGAGAACAGAGGCCCTG
GGGTGTGCTGGGACTTGCCTGAGGCCTCAGACCGGGACTGGGTGCTCCTCCGCACCTCCTATGAGGGAGGGTGTCCGTGTCTGTGAGGAC
AGCTCAGCAGGGCTGGGAACCTGGGGGCAGTGCTGGGGGACATGTGTGAGACTAGCGTGTGTGGGCCTTGCTCGGCTTGCCCTGGTGCCC
TGAGAAAAACCTGGTATTTGAAAATACACATGGACTGCTGGAAGGTCAGGAAATCCAGGGTTTTGTTCTGAGGCAGTGGAAGTGTTACCG
TGAGCCTGTGTTGGCCTCTCTCCTCACTCCACCTGCAGCCAATTCAGCCACACTGCCTTTGCATGGAACCCAGGGTTGCAGGCCGCGTGT
GTAGATGCTGATTTAGGCCCAAGCACTCAGCTGTCAGCAGGAAGGACCATAGTGTTTTCTTCTAGTTTTAGATATGCACTCGTTCTGTGT
TTTAAAGTCACAGCTGTGAGCCAATATGGGAAGAAGTGAAGTGGCCTCTAGGAGGGACTGAGCACCCTGTCCTTGGAGGTATGCAAGCCC
AGGCTACACCCTTCCTGTCTGGGATGATATGGCTGGGGGTGGGCTTTGTGCTGCGTGGACCATGGCAAGCCTTTCCATCTCTGAGAGGTA
GTGGTCCTTCCCGTGCCTTCTGTTAAAGATAATTTTTTAAAAAAAGGCATAACTCATATATATTACATGTACACATGTCAAAGATTTTAT
TTAACTCAGTAATTGAGAGTGCTGCTAAGATTAACAGCCAGTTCAAAAGAGAAATCACAATGAACCATAAATCTGTATGGAGTAAAGGAA
AGTTGAAACTGGCTGGGGTTTTTTTTTTTTTTTTTTTTTTTGAGGAGAAAGGTCAATTGAATCTTATTCGTATAATATGCACATCCATAG
ACAAGAATTATTTTGCATTAACTCTACAACTTAGTTGTAAAAATAGCTCAAAGGCAGTGAAAGACTAGAATCAGATAATTGGAAGGGTGC
ACCCTAAGCAATGCATAGTTCTATTTTCTTTCTTTTTTTTTTTGAGACAGAGTTTCCCTCTTGTCACACAGGCTGGAGCGCAGTGGTGCA
ATCTTGGCTCATTGCAACCTCTGCCTCCCGGGTTCAAGTGATTCTCCTGACTCAGCCTCCTGAGTAGCTGGGATTACAGGCGCATGCCAC
CACAACTGGCTAATTTTTGTATTTTTAGTAGATACAGGGTTTCACTGTGTTGGCCAGGTTGGTCTCATACTCCTGACCTCAGGTGATCCA
CCCGCCTCGGCCTCCCAAAATGTTGGGATTACAGGCGTCAGCCACCACGCCCGGCCCCAATGCATAGTTTTTTACTGAAGACAACCAGAA
TCTCTGTTGCTTATTCCAAATTTCCTTCCACCACTTGTCCATCCAGCAGAGCCACTTTTAAAATAGGACACAGGCAGAAATTTAAAGGAG
TCAATATCTCATGGTGAAAAGTGAATCCTGAGGGTTAGAGCATCCACCAGGTGCCCTAGGTAAGGGCCAGCCACTCTGGGAGGCAGCCCG
GGGCACTCACTGTCCTCTCAGTAGTAAATGAAATCACTCAGGCCATGTCTGCTACCCAGAGAGCCTGAGTGTCCTCAAATGCTTGTTCTG
CCTCTCCATCCACTCCTGCAGACACCTCAGTGGCTGCATCCCAAACCGCTGAACTTTGCTTCTCTTTCTCCAACCCCCAATTCCACCCAC
ATCCAAAACTGCTCTGCCCCCTATTCCCATCTCAGCTGAGGGTACTATCATCCACCCTGTGGCCACATCCAGGAATGTGTGTATCACCTG
GGCTCTGAGGATGACATCAGCTCTTCTAAGTCAACAGAATGTCGGGTCTGTTCTAAAAGTCTCATCTGACAAGGAGATCTTTAAGGCTTT
ACTCCCTTAAAGGCTTTACTCCCATCATGATGGGATAACCATCATGATGGATTTCAGTGTCATTCTGTCTTTTTCTTCGGAATGATTCCT
GGGACTCGCCTTGTTTGCAACATGTGCATTGAAATATCTTTTCAACATAACTTTGTTCTTAATTGTGTTTACTTCCTTTCTCTGTGAATC
TCAGTGATTCCTGGAAGCTGTGGTTGGTGGGGGATGGGGTGGGAGGACTTTGGTAGTATAAAAGAGTACCTGCAATGAATGTTCTAAGAA
ACTGGAGTGTTGGGGTCCTCCAGCCCTTGGCTGGTAAACTCTCCACTCCTTCCTCTTTGCAACACAATTCTCATAACTGGCAAAGGTGTG
CATGTAAAATTTGTGACTGTAGTCTGAGGTTTTTTTTCCCTGTACAATTCCGCCTTCCCCCCTGTAAGCCTGTACCAGGAGAGGTCTCAG
CTGCCTTGGAGGCGGTGAGACACGTGGGTGCTCACTGTGGCCCTCAAGGGTGAGGCTGGCACTGGGGCATCTGGGGCCAGAAGTCCTCCT
TTAGTCCCAAGTCTCTGCCACTCAAGTGCATCAGTGAGAGGTCCTCATAGAAAATCTACTGTGGGCACAAAGCTGCCAGGCTGATGGGGG
TGGGGAGCAAACGAACACCCTTTTCCCCTTTTACACCAGAGGAAAGAGACTTAGACTGAGGAACTTGCCTGCTGCCAGACAGCTGGGAGG
TGGTAGAACCGGGCTTACAGCCCAGGGTTTCCACTCTAGGAACTCTTCTCCCTTCCTCTGATGACACTAACTCGCAGGCCATGATCAATG
AGCAACGATGTAGGCAGGCACTGACGAGGCACAGCAGGAAGGCAGCTCAGTGCCCATGACGGCCAGGAACTGGGTACCATTTCCTCAGCA
AAATGGGATAGTAACTCCCACACTGCAGCTACGCACTTGGGCAGTGGTTCACAAGGCCAGCAGCCACAACATCACCCCAGACCAGCAGCA
GCTGCAGCATTACCCCCAGCACTTGTTAAAAGATGCAAATTCAGGCCAGGTGTGGTGGCTCGTGCCTGTAATCCCAGTACTTTGGGAAGC
CAAGGCGGGTGGGTCACCTGAGGTCAGGAGTTCGAGACCAGCCTGGCCAATGTGGTGAAACCCTGTCTCTACTAAAAATACAAAAAATGA
CCCGGGCATGGTTGTGGGCGCCTGTAATCCCAGCTACCCAGGAGACCGAGGCAGGAGAATCACTTGAACCCGGGAGGCAGAGGTTGCAGT
CAGCCGAGATTGTGCCATTACACTCCAGCCTGGGCAACAAGAGCGAAACTCTGTTTCAATAAATAAATAAAAATGCAAATTGTATGCCCC
TTCCTTCAGGCCTATGGGACCAAAAACTGGGATGGGGCCCAATAAAATGTTTTAACCAGCCCTTCGGTGGTTACAGAAGGATAGAGCCAG
AATAGACTAACCACTGTAACAAACATTACCTATACTTGGGAGGCTTTGAAAAATGTTTATTTAGCCGGGTGCGGTGGCTCACGCCTGTAA
TCCCAACACTTTGGGAGGCTGAGGCGGGCGGATCACGAGGTCAGGAGATTGAGACCAGCCTGGCTAACACAGTGAAACCCCGTCTCTACT
AAAAATACAAAAAATTAGCCAGGTGTGGTGGCAGGTGCCTGTAGTCCCAGCTACTCTGGAGGCTGAGGCAGTAGAATTTCTTGAACCCAG
GAGGCGGGGCTTGCAGTAAGTCGAGATCACGCCACTGCACTCCAGCCTGGGTGACAGAGTGAGACTCCATCTCAAAAAAAAAAAAAAAGG
AAAGAAAAATGTTTATTTTTTTGCTCATGCCACAGTCTCTGGTAGTTGCTGGGAACTAGGGTGGGGGATTCTCTGCTCCACACAGTCTTT
CATGGACCCAGGTTCCTTTCCTGTTGTGGGTCCAGCCTCCTGTAGCTGTTGGAGGCATCTCTAGTCAGCTGGTGGTTGGGGAAGAGGTGA
GGATCAGGGAGGGAAGATGGAGAGTACTCTGCTTGTTCTCACATTCTGCTGGCCAGAACTCACAAGCCACCTGAAATGATGCAAAGGTCT
AGCTGTGTGTGTAGGAGAAAGAAGAGAGGCCAGATATTGGAAGACAGCAGTGGTCTGTGCCCCAGGCCCCATGGTTTAGGGAAGTGAACC
TTGGCACTGGATTTCCTGGCTTTCTAAATCTCCCTTTATAGGGAACTTAGGGCCCAGTCTGTGGTGGGTGGATTTGCCTGGTTCACAGCC
TCTGGTCAGCCTTCTTTCTGCTCCACAGGGCGGCCTGGAGATGGTGGGCTCCTTGTCACACTGGTTGGGGATGTGGGCTCCATGGGGCCA
GAGATGTGTGTGCTCTGTGTTCAGATTAAGGGACAGACGGCACATGAATTCCTTCAGTGCCCTCCAGATTTGGTCACTGGGGAGGGGTAG
GCTGAGCAGTAGCTCTTGGGTCTGTAGTAGTGTGACCCTGGAAGGACTGTCCAGCTGAAAACAAGAGCCTGGGGCGTGGGGAGGGGAGGG
GTTACTCAGGGTTCCATGAGACCTGGGTTTAAGTCCTGGATCCATCATTAGCAGCTATGTGAACTTATGCCTCACTTTCCTCAAATATGA
ACTTGAGATAATGAAATTACCTTCCTCATAATACTGTTCTAAGAATTGAATGAGGAAAGGTTTACAATTCGGCCCTGGTTGTTCCACTGG
GGAGGGAACAGAGATTGGGGGCACAGGGCTCCCCTGGCCTGGGGGAGTCTGGCTCACTCAAGTTCTCAGTCATTTGCAAGGCAAGGACCC
TGCTTCTCCTTGCTCTGGGTCCGAGTAGTCTCAAGCCCAGTGGGCAGGGCCTGTGGTGTGGATGGACTCGTCTGCAGTGAGTCAGGCAGC
AGGCAGAGCTGGCAGGCTGTGTGGTCTCTAGTGGGTACCAGGGGACCTGGGAGGGCCTTGTGGGAGGTTGTCCACGGTGTGAGCCAGTTT
GCCATCTGGGGTCCTGGAGTTCCCTCCCGCCCTTTGAGTTAAAAAGAGTCAGTCCTGGGCTGAGACTTAATTGCGCTAGTGCTGAGTGAC
CTTGTGTCAGGGGAAATCGGATGGGGCAAAGTGTTTTTTAATTAGCAGGACTCACTGACCTTTCCTTCACTGTCAGCAACTTCTCACAGG
GAGGCAGAGCAAGGGGGGCTGGAGCCCCGCATCTCTCTAATGGAGCCTATGTCCAACAAGGAGGTGGATGGCTGGATTCAGGGCCCTGGG
AGGACTTCATGTGGGAAGCAGACCTCAGGAAGGGCCCTTAGTGATGGTGTGGGCCAGGGTTCTCACCTCCTTAGTCTCCTGTCCTGTCCA
TCTCCGCAGATCCTAGGCAAAAGAAGCGGAGAAACACTCAAGCCACTGGGGTGGTTAGGGCACACTGGTGGCAACTGTTTAAAACCTTAA
CTAAAACAAGGTTAAGCAAAAGGAGTTTACAGGCTCTCATAGATGGGAAGGATGTGGGAGGGTCACAGACTGAGAGGAACCAGGGCTGTG
GCTGCTGGAAGGAGCCTCACCACCGCCAGTGTGTTTCCTCCCCGTCGTCGGCATCTCTGCTTCTCTCTGCACGCCAGCAGCTCTCTCTTA
GGGCACGCAGACCTTTCCTCTGCAGGGGAACACGAGTGCCGGCAGCCCCGAGTTAGTGACTATCATAGAAACTCAGTGTATTTCTCTCTT
GTTTATCATTCCGAGTCCTGAGTCACAGGCTTGTCCAGCACTCAAGACTTTTTCTTTTCTCTATTTTTTGAAACGGATTCTCGCTCTGTC
CCCCAGGCTGGAGTGCAGTGGCCCGATTTTGGGTGCAAGCGATTCTCCTGCCTCAACCTCCCGAGTAGCTGGGACTACAGGTGTGCGCCA
CCACATCCAGCTAATTTTTGTATTTTTAGTAGAGACGGAGTTTCACTATGTTGGCCAGGCTGGTTTCAAACTCCTGACCTCCCGCCGGCC
TCAGCCTCCCAAAGTGCTGGGATTACAGGCATGAGCCACCACGCCTGGCCAAGATTTTTTCTTTTAAACCTGGAGTATGGAGATGCTCAC
TAGGCAGACAGAATCAGCCACCACAGCCCACTCCCTCAGCCAGTATTACTTTGACTAAGTTAGTGAGGAACCAGGCCCCAGATTAAGAAG
CAGAACTCACACTGTCATCTGCTGTGTGCCTGGCTGGCTCATGCATACCTTGTCTATCTAATGTGGACCAAAGCCCTGTGGCACACCCTG
CTGGTTACCCCCAGTGGTTACCCTGGCACAGAGGAGGAAAGGGAGTCGTGGGAGGGAGAAGGACTTCCCTGGGAGGTCTCTGGGCTGGCA
AGTTGGGTGACACAGGTCCGGTTGGCTGCAAGCCTGGGCTCTGCTGTTGTAATCATAAATGTGTGTGTGTGTACAGTTGTTTACAATGTC
AGCATGGGTGTCCTTGTTTGTTAGAGATACATGCCACTGCTCCCATCATGAGGAAAATCCCAAGCCCTCCCCATGATTTTTGCCAGTTTC
TGGGGACTCATGCTCCTGGCAGCCCATGTGTCCCCAACTCCTGTGTCCTTTAGGGACCTCTGTTGAGCCCTGCCTCTATTCTGGCAGAAT
TAGAGAAAATTCTTTAAAAAAACAATAAAGTTTAAATTCATTTAAAAAAATAATAAAAAATCTCACAGCATGAGTTTTGATGAGATTTGG
GGCAAGGTGGGCCACAACCTTGGGTTGTATGGCCACCTCCCCCTCTTCTTCCCCTGTTGTCTCTGCAGCTCAGAAACCCCAATTTCCTGG
CCTGTGTTATGTGGAGGAGCTGAGCTCACCCCCTACAGCTTCATCTCCAAACCTAGCAAGGATCCTGCCCAGATCAGGAGATCCTCCTTT
TAACAGAAGTTATTTACACTCCTTAGAAAGCAGTGGGGGTGGAACGATTCTTTTTCCTGATGCAGAGATGTAAAACTGGGACATTGCTAC
ACATAATATTTTAAACCTGTCTTCCCTCTTACCAACGAACACATCACTAGCACCATCTATGCCAATACATTTCTCAACATCAATTTCAGT
GGCTGTATTACATTTTATCCTACGGATGTGCTCTCATTTATAATCTAAACCACTTTTATTGAACACATCAGTTATTCTGAAATTTTCAGT
GTTATGATGGATGTTGCAGTAATTATTCTTATATATGCACAGAACCCCCAGAGGACATGACTACTGAAGGCTGTGCTGGCAGGATCACAG
GTAAGGATCTAGCAAATTGTCCCAGCTTCATTGACTGAGCTTTCATCCTTGTTGCACTACTTTGAGCTGCCATTTTGATCATATAATAAT
GATTTAGTAGAGCTCTTTTTTGGTTCAACCTACCTGTTCTTGTATCAGAACTGAAATGTTTGATTTTATAAATTTGAATAGTGGCACAAT
ATAGAGTTCACTATTCCTCAATATTTTCAAGGCTGTTTCTTATCTGTTCATTCTTTTGGTTAACTTGGGAATTATTTTATCAAGTCTCTC
TACTTCCCAATTTCCTTTCACCTTTGGCTCGAAATGATATTCAATGTATACATTAACTTGAGTTACATTTTGCTGCATAATGCTTGAGTT
ACATTTTGAGTATTACGTGTTACTCATAATACATATTGAGTTACATTTTGCTGCATAATACATTATCCCCAAGTTTAACACCTTAAAGCA
GCACATATATATCTCATACCCTTCTGAGGGTCAGGAATCTAGAAGCAGCTTAGCTGGGTGACTGTGGCTCTGGGTCTCTCATGAGGCTGC
AGTGAAACTGTTGGCCAGGGCTGGAGGATCCCTTCCAACCTCACTCCATGACTGTTGGTGGGAGGCTTCAGTTCTCCACCTGGTTCTCAC
AATATAATTTCCCCCAGAGTGAGTTATCAGAGAGAGTGTGCAACCAGTAATCTGTTAGAATATGTCACGTCTGTCATATTTGATTGGTCA
CTCAGACCAACCCTAATAGATGCGAGAGTGACTATGCAAGGGTGTGAGTTCCAGGAGGAAAGCATCATTGGAACCATCTTGGAGACTGGC
TAATACACAGATAAATGGCACATCTGACAATATGGCATCTTTCTGAGTGTCAGTGTGGTGTGTTCCTATATGAACTTAATGCTATTAAAC
TTAATTAAATTGTAGGTATGCTCTCAGTGAAGATTTTTACTTTTACATTACAGGTTTCCACACTGTTAAATTCATTCCAAGTATTTCATA
CATGCTGTTCCTATTATGAAAGGATCTTTTTTTTCACATGGCATTTTCTAAGTAGTTGTTGCATTCATATAGGAGATGCTATTGATTTTG
ACACCCATAATTTTTCAGTGGAGACAAGGCAGAAACTACTCCAGACTCTCACCTGCTGTTGCTGATCCTTACATGGTGGCTGTGCCAGGC
TCAGCCGCGCTGAGATGACAGGGCTGTCTGGCCATCATTGGTCATATGGACTTCAGATTTGAAAGGATTTTATGTAGAAGCAGAGTGCCT
GATAGGACTCTCCGGGACCCCCATTTCTGCCCTGCTTGGCTCCCACTGGCAAGGCTGGCTCAGTTCCTGTCACCTTCTCCTGGACTTTGG
CCAGAGTCCACTGGCTGTTTCCCCTGCCTCCTGCTCTCCCAGTGCCCTCTCCACACCAGTGCCAGAGCTGCTTCTAAGAGATGCCTCAAA
GCCCGCTTCCAGCTTAGGAACCCCAGGGAACATGGATGGTTTCTCCATTGCCACTTCCTAGCCTTCCTGGCATAGGAAGGTCTGGTTTGC
CTGCAGGTCCCTCTCTGGGGGGGTCCCTGCTCCATAGATGCTGAGGCTCCAGAAGTCTGTTCTTTTATATCACATTTGAAAACCTTTGAA

>55722_55722_2_MTMR10-TSPAN14_MTMR10_chr15_31266517_ENST00000435680_TSPAN14_chr10_82264482_ENST00000429989_length(amino acids)=401AA_BP=158
MFSLKPPKPTFRSYLLPPPQTDDKINSEPKIKKLEPVLLPGEIVVNEVNFVRKCIATDTSQYDLWGKLICSNFKISFITDDPMPLQKFHY
RNLLLGEHDVPLTCIEQIVTVNDHKRKQKVLGPNQKLKFNPTELIIYCKDFRIVRFRFDESGPESAKKLAGVVFLGVGLWAWSEKGVLSD
LTKVTRMHGIDPVVLVLMVGVVMFTLGFAGCVGALRENICLLNFFCGTIVLIFFLELAVAVLAFLFQDWVRDRFREFFESNIKSYRDDID
LQNLIDSLQKANQCCGAYGPEDWDLNVYFNCSGASYSREKCGVPFSCCVPDPAQKVVNTQCGYDVRIQLKSKWDESIFTKGCIQALESWL

--------------------------------------------------------------
>55722_55722_3_MTMR10-TSPAN14_MTMR10_chr15_31266517_ENST00000563714_TSPAN14_chr10_82264482_ENST00000429989_length(transcript)=16451nt_BP=572nt
CTCCTCTGCGCTTCCGTGGAGCCTCCAGGCCGACCCCCGGGAACTGGAGGACCCCAGGAGGCTGCGCGCGTCTCCCTGCCCACAGCAGCG
CGGCTGCCTGATTCCCGGCGCCGCGAAATGCGCCTTCTCGGGAGCCCCCACTGGCTCGGCGAAAACTTACTGACGATAAGATCAATTCGG
AACCGAAGATTAAAAAACTGGAGCCAGTCCTTTTGCCAGGAGAAATTGTCGTAAATGAAGTCAATTTTGTGAGAAAATGCATTGCAACAG
ACACAAGCCAGTACGATTTGTGGGGAAAGCTGATATGCAGTAACTTCAAAATCTCCTTTATTACAGATGACCCAATGCCATTACAGAAAT
TCCATTACAGAAACCTTCTTCTTGGTGAACACGATGTCCCTTTAACATGTATTGAGCAAATTGTCACAGTAAACGACCACAAGAGGAAGC
AGAAAGTCCTAGGCCCCAACCAGAAACTGAAATTTAATCCAACAGAGTTAATTATTTATTGTAAAGATTTCAGAATTGTCAGATTTCGCT
TTGATGAATCAGGTCCCGAAAGTGCTAAAAAGTTGGCTGGAGTTGTCTTCCTTGGAGTCGGGCTGTGGGCATGGAGCGAAAAGGGTGTGC
TGTCCGACCTCACCAAAGTGACCCGGATGCATGGAATCGACCCTGTGGTGCTGGTCCTGATGGTGGGCGTGGTGATGTTCACCCTGGGGT
TCGCCGGCTGCGTGGGGGCTCTGCGGGAGAATATCTGCTTGCTCAACTTTTTCTGTGGCACCATCGTGCTCATCTTCTTCCTGGAGCTGG
CTGTGGCCGTGCTGGCCTTCCTGTTCCAGGACTGGGTGAGGGACCGGTTCCGGGAGTTCTTCGAGAGCAACATCAAGTCCTACCGGGACG
ATATCGATCTGCAAAACCTCATCGACTCCCTTCAGAAAGCTAACCAGTGCTGTGGCGCATATGGCCCTGAAGACTGGGACCTCAACGTCT
ACTTCAATTGCAGCGGTGCCAGCTACAGCCGAGAGAAGTGCGGGGTCCCCTTCTCCTGCTGCGTGCCAGATCCTGCGCAAAAAGTTGTGA
ACACACAGTGTGGATATGATGTCAGGATTCAGCTGAAGAGCAAGTGGGATGAGTCCATCTTCACGAAAGGCTGCATCCAGGCGCTGGAAA
GCTGGCTCCCGCGGAACATTTACATTGTGGCTGGCGTCTTCATCGCCATCTCGCTGTTGCAGATATTTGGCATCTTCCTGGCAAGGACGC
TGATCTCAGACATCGAGGCAGTGAAGGCCGGCCATCACTTCTGAGGAGCAGAGTTGAGGGAGCCGAGCTGAGCCACGCTGGGAGGCCAGA
GCCTTTCTCTGCCATCAGCCCTACGTCCAGAGGGAGAGGAGCCGACACCCCCAGAGCCAGTGCCCCATCTTAAGCATCAGCGTGACGTGA
CCTCTCTGTTTCTGCTTGCTGGTGCTGAAGACCAAGGGTCCCCCTTGTTACCTGCCCAAACTTGTGACTGCATCCCTCTGGAGTCTACCC
AGAGACAGAGAATGTGTCTTTATGTGGGAGTGGTGACTCTGAAAGACAGAGAGGGCTCCTGTGGCTGCCAGGAGGGCTTGACTCAGACCC
CCTGCAGCTCAAGCATGTCTGCAGGACACCCTGGTCCCCTCTCCACTGGCATCCAGACATCTGCTTTGGGTCATCCACATCTGTGGGTGG
GCCGTGGGTAGAGGGACCCACAGGCGTGGACAGGGCATCTCTCTCCATCAAGCAAAGCAGCATGGGGGCCTGCCCGTAACGGGAGGCGGA
CGTGGCCCCGCTGGGCCTCTGAGTGCCAGCGCAGTCTGCTGGGACATGCACATATCAGGGGTTGTTTGCAGGATCCTCAGCCATGTTCAA
GTGAAGTAAGCCTGAGCCAGTGCGTGGACTGGTGCCACGGGAGTGCCTTGTCCACTGTCCCCCTGTGTCCACCAGCTATTCTCCTGGCGC
CGGAACTGCCTCTGGTCTTGATAGCATTAAGCCCTGATGGCGCCGGTGGCGCGGTGGGCATGGTTCTTCACTGAGAGCCGGCTCTCCTTT
TCTTAAAGTGTGTAAATAGTTTATTTATAGGGGTAAGAATGTTCTCACACCATTTCACTTCCTCTTCCTCTCCTCCAGCATTCTCCTCTG
AGCAGCCTTAGATAGTGTCCATGGCTGGAGCCGACCCTTTGAGTCCCCTTGAGTGTCTTAAGAACCAGCCCACAACAGCCTCTCTTTCTC
CTCCACATACTGCAGCCTCCCTCCATGCATCCCACATACAAGCACTCCCCCACTCCCCAGCGTGGCCTCACTGTCTTCTGGTCTTGGTGC
TACTGAAATTGTCACCCAGAATTTGAATCCTGACCCTCCCCACTGCAAGCCCAGGGAGCCCCAGCCCAAGATGGCCAGCCTGAAACTGTT
GGCCAGGGCTCCTCTTGTGGCCATGTACCCAGGGCTGGCTGGCCTGCCATTTGCCTCTCCCCGGAGACAGCCGTTCTTCTGCAACCACAC
CCCGTGCCTAGCCACAACCCCAGGCTGCAGCTGCTCAGAAGCTCCAGGCATTTTGTTTCTGGTGACCGCCCCTAATGGGATATCGGTGAT
CACTGGTCCACCCTTCCTGTCAGGGCTTTTCTGGGGCTGCTCTTGGAAATGAAGTCTTAAGTACTGAATAACTCCCCTGGGGATAGCTGG
GGCATTTGTCTAGCTGGGCTACTTTCTAACACTTTGCCATAGCTCAGACCACTTCTCATCGTTCAGGGATGGACTGCAACCTTAATTTAC
TTGCCGGAGTGTACATTCTAGTGTGGTGTATACTGGTGGCTGTTGATGATGATTTTTTTTTTTTTACACAATTCTCTGTAGACTAGGAGA
AGAATGCTTGTGTTTTTCGGAAGTGTGATGCTTCTCTTTGACTGCCAAACTCTTTTATGGAATATATCTTTATATTAATGCTGTTTTGGT
CATTTTTGTTTGGGGTCACTATTGAGATATTGCTAAGCATCTCAGTGGTAAACGCGGCTGCCAGAGGAACCAAGGGATAGGGTATGTAGA
CCTTACAGAAGGATGGATGGTAAAGGCAGTCCATCATCAGCACAATCTGACTTACATTTCATTGAGTAATTTTTTTTTTTTTTAAGATTC
TGTATGGCAGCACTTTCAGTTGCCCTTGTGTGCCGGCCACAGCCGCACAAGTTGGCTTGTGGTTTATCCCCCGCTATAAGTGAGAGCTGG
AGAAACTTCAACTCCATAGGTCTAGAGGAAACATTGTTTTAGGTTATTTCTGTCCACCCCTGTGCGATACTATTTATTGATCCAAGCAGA
AGAGCTTGGGGACACTGAGTCGAAGTGGGGACATGGGATTGAAGCCTGGGCACTGCTGCTGCATGAGCTGTGTGTCCTGGGTGTGCCGGC
CTTTCTGTGAAGGGGGTTGGTGGCAGTGCCCACCTCACTAGATGCCTCTGACCCAGCCTCCCCTGGGGGAGTGGGTGGCCACAGACCCTC
CCTGCCAGAGCTCCTGGAAGGCTCCTGCAGGCCTGACCCATCTATTCCTGTAGACCTGGTTTAGGATGAAGTCTCGGTGCGATTTTTGCA
GAGTTGGGTTTATCTTTCAACTATAGACCCTTCTGGCTGTTCTCAGCCATATCATGTGACTCTGAATAGTTGGATGAGGAATGGAAAGAA
AGCAAGGATGAGAGCCGGTCACGTGGCAGTCTCCGCCCAGCATCGGCTGTCCGCACAGAGGCACAGGGCAGGCCTCCTGTGCACTCCCCA
CCTAGCACTGGCCTGTCCTGAATCCCCGCCTTCCCTGGTTGGAGGCCAGCTGTGGCATTTGCACCCTCTTCTCACCTCACCATGCACATG
CTAACTTTAAAGCCTTGGGGTCTTTCCTGTACCCCCTCCTCAACCCTGGTCCACCCCCTCTCAGGATCTTGTCAACGTTATTTTTCCTGT
CCCGTCTTCCTATCGCTGGCCTTCCTTTCCCATCCTAAAAACTTGCCGAGGCCCTATGGCTCCCTCCCTTTCTTTCCCAGGCAGCTTCTT
ATCTGGGCTGTCTGTACCCCTTCCTTTGCACCACCCACCATGCCCCACGTAGCTGAAAGCTGCTTATCCCAATTGTCAACTCTGGCCTTC
TTCAGCCTCTGTAGCACCAGACACTGCACCTCCTGAATGTCCTCTGCTTCTCTGCTTCAGAGGCCCAGGCTCGCCAGTTCTCTGACCTCT
CCCATATGTCTGCTTAGGACTCTGCTGCAGCTGTCCTCACCAGCCTCCGGGGAATCCCACTACCCACAGGGCAGGGCTGTGGGCTGGGCT
GAAAAACCATCTGCATGGTCCACAAGAAGCCTGGCACTGGGTTTCCCCATGAATAACAATGAAAATTAATGGATGCACAACCTTCCTGGA
ACGTGGAATTTCTCTGGGAGATTCCATGCAGAGGCCACTGGGGAGGTGGCAGGCATGCATGTGACTGTAGGTGGCTGCAGTGTTGGAAGG
CTCCCAGCAGAGCAGAGAGGGTGTCAGTCTCATCAGGGAACCCACCTGATGGCTTCTCAGCCAGCAGTCTCAGAGGAACATAGACGACTG
CTGAGAAAGGAGGGAGGCAGCAGTGGTCCCAGCACCTGAGGCATCCTGCTGTCATGGGAAGGTCTCCGCCCAAATGTCAGATGCATCAGC
CTGTCACCCGCTGGTCCAGAGCTTTCAGCTGTACTGGTAGGGGGTGGGTGGTGGAGTGCTGAATGACCTTCACAGGTGGGCCTTTCCAGC
TCTAGGGTCTTACGGGTGTCGGTCCACAGAACCACGGTTTTTAGGTTGTGTGTCCGGGGCTATGGGAACCTGTCCCCCATGATGGATCTT
GGTAGAGACACTTCCCTCTGTCATCGTGCCCAGGAGGATGCTGCAGGTGACTACCTGCAGCCCTGTTCTCATTCATTTGGATGCCCTCCA
GAAATCTGGGGAGCCATACACCTTTAGAGCCTTTTTTGCTCCTTATCAAGTTGGCAAGGCTTGGCCAATTCCTGTTCAAGGCTGCATTAA
AGGCATGTTCACCATCCTGGCTAATACGGTGAAACCCCTTCTCTACTAAAAATACAAAAAAATTAGCCGGGCTTGGTGGCGGGTGCCTGT
AGTCCCAGCTACTCCGGAGGCTGAGGCAGGGGAATGGTGTGAACCCAGGAGGCGGAGCTTGCAGTGAGCCGAGATCACACCACTGCACTC
CAGCCTGGGCTCAAAAAAGAAAAAAAAAAAAAAAAAAAGGCCCGTTCATTCTCAAATGCTTTTGGCGTCTCCAGGGTGCCTCAGGAAAAC
ATGAAGTGGGCATTGTAGAACTTGGGGCTACTGTGTAACTTTGGAAGAAAAAGTTAAGGGTACTTTTAAGTGGATACTGTTTTGATGAAA
TTGCCAACTTCAGGGAGCCCAGCTTGGAGAAGGAGGACGTGAGTATTCCTTACAAGGCTCCGAAACAATTCTTTCTTCACTTAGTTTTCT
TTCTGTGCTCTGCATCTTATATTCCAGCAGGGTCTTCCAATGCATGGTTTAATAACTACTAGAACTGGCCAGGTGCAGTGGCTCACGCCT
GTAATCCCAGAACTTTGGGAGGCTAAGACAGGCAGATCACTTGAGGCCAGGAGTTCGAGACCAGCCTGGACAACATGGTGATACCCAGTT
TCTACTAAAAATACAAAAATTAGTCGGGCATGGTGATGTGCACCTGTAGTCCCAGCTGCTCGGGAGGCTGAGGCAGGAGAATCGCTTGAA
CCCGGGAGACAGAGGTTGCAACGAGCCAAGATCGAGCCACTGCGCTCCGGCCTGGGTGACAGGAGACTCCATCTCAAAAAATAAAATTAA
AAAAAAACTACTACAATAAATTATCACCTTGGACTGTATAAAACAACTTTTAAACTAGTCTTTTTAAAAAGTACACTTAAATAAAAATCT
AAACATAAGAGAATGTAAAGTGAAAAGTGAAAGTATGTCTTCTGTTACGCAGAGGTAACTACTATTAGGAATCCTTCCTGAAAATGTCCA
TGCATCTACTCAGGTCATCACACCCATGGAATCATTTTACATACTATTTTATGAGTGTTACTTAATATACTGATCCACAGTGCGTTTTCA
CGGTCACGCCATCAGTTGTAGGAGTGTGCCAAGAACAGATGGGCCTTGCCTTTGTACCAGAGGAGTCCATTTACAGTTGCAGGTAATAGA
AAACCCAATTCAGACTGGCCTAAACAATGAGGGGAGGTTTTGGCTCTTGAAACTGGAAAGTCCCAAGGTGGGGTGAGTTTCAGGTTTGGG
TTGATCCAAGTGGCTCAGTGACGTCAACAGGATCTTGTTTCCATTTCTCTGCCTTCCACAGCCTCCCCTTCATCTATGGTGGAGGGAAGG
AGTCTACCACAGACAAACCCCGAGCCTCCCCCTGATGGGTGGTGTGGTGGTGAAGCCAGCAAGGGAAGGGATCCCCGGACACACCCCTCC
TCATGCTTTATCCCACTGAAACCATGCGGCTGTGAAATGCAGCATCCTCCAGGAGGGGGATGAAGGCCGGGGATGCTGTCAGCTATTGCC
ATTGCACTTCTGTGGATGGGTGTTACAGTTTTTTGCAGGGTTTTGCACTTACAAGGACATATATATATATATATAAACTACAGTGTTATT
GGAATTGCTTCTTACAGTTTGTAAGAAAAAAACATGTTTTTAGAGGAGTTCTCCTGGGAGGTGGGATCACATTTTTTTTTTTTTTTTTTT
TTGAGACGGAGTCTCGCTCTGTGGCCCAGGCGGGAGTGCAGTGGCGCAATCTCGGCTCACTGCAAGCTCCGCCTCCCGGGTTCACGCCAT
TCTCCTGCCTCAGCCTCCCGAGTAGCTGGGACTACAGGCGCCCGCCACTACGCCCGGCTAATTTTTTTTGTATTTTTAGTAGAGACGGGG
TTTCACCGTGTTAGCCAGGATGGGGGATCACATTTTAATAAGTAGGTACTCAGGGCTGGGGTGTACCTGTTGCTGCCTGACCACTGCTGG
TGTGTGTGGGTATAAGGTGACAAAACCTCCTACCCCTGTGAGGTTGTTTCAAGGATTAAATGAGTTGAGATGGGTAAGCATCTAACAAAG
ATCCAGATTATTTAGTATGCATCCCCTGAATTATTGCTAACATAATTTTAATGATTGGGGAATTTTATCTGTGGCTGCCAGTCCCTACGA
GAGAGCTGCCTGGGTCACATGTCAGATAGCTCAAGCTTTGAATCACTGAAACGAAACGGTCCACTTCCCTGTCCCTTTAGGAACAAGGCT
TCGAGGTCTGTGGCAAGCCTCAGCAGGCATTTGGAGTTCAAGGTCTGTTCTCTTTCTGTGCCATAGAGGTGGGGAGACAAGGTAGGGTGT
TGCTTCTTGCCTGGAGCGCAGATGCTACCAGAAACCAACACAACCAAAGTTGCCCGGGAGCCCCCAGAAGCAGCAGAGTGGCCATCAACT
GCCAAGGGGCCAGGGTAGGCCACAGAGGCCTGGGGCCCAGGAGGGATGGTCTGTGGGGAGAAAGGGGATTATTGTGAACATCAACGCTGG
GGATAATGTGCCCTGAAGACAGCAGCATATCACGTTTGGACGGTTGGTGGACCCCATCTGGTCCCACTCATAAGGAGAACAGAGGCCCTG
GGGTGTGCTGGGACTTGCCTGAGGCCTCAGACCGGGACTGGGTGCTCCTCCGCACCTCCTATGAGGGAGGGTGTCCGTGTCTGTGAGGAC
AGCTCAGCAGGGCTGGGAACCTGGGGGCAGTGCTGGGGGACATGTGTGAGACTAGCGTGTGTGGGCCTTGCTCGGCTTGCCCTGGTGCCC
TGAGAAAAACCTGGTATTTGAAAATACACATGGACTGCTGGAAGGTCAGGAAATCCAGGGTTTTGTTCTGAGGCAGTGGAAGTGTTACCG
TGAGCCTGTGTTGGCCTCTCTCCTCACTCCACCTGCAGCCAATTCAGCCACACTGCCTTTGCATGGAACCCAGGGTTGCAGGCCGCGTGT
GTAGATGCTGATTTAGGCCCAAGCACTCAGCTGTCAGCAGGAAGGACCATAGTGTTTTCTTCTAGTTTTAGATATGCACTCGTTCTGTGT
TTTAAAGTCACAGCTGTGAGCCAATATGGGAAGAAGTGAAGTGGCCTCTAGGAGGGACTGAGCACCCTGTCCTTGGAGGTATGCAAGCCC
AGGCTACACCCTTCCTGTCTGGGATGATATGGCTGGGGGTGGGCTTTGTGCTGCGTGGACCATGGCAAGCCTTTCCATCTCTGAGAGGTA
GTGGTCCTTCCCGTGCCTTCTGTTAAAGATAATTTTTTAAAAAAAGGCATAACTCATATATATTACATGTACACATGTCAAAGATTTTAT
TTAACTCAGTAATTGAGAGTGCTGCTAAGATTAACAGCCAGTTCAAAAGAGAAATCACAATGAACCATAAATCTGTATGGAGTAAAGGAA
AGTTGAAACTGGCTGGGGTTTTTTTTTTTTTTTTTTTTTTTGAGGAGAAAGGTCAATTGAATCTTATTCGTATAATATGCACATCCATAG
ACAAGAATTATTTTGCATTAACTCTACAACTTAGTTGTAAAAATAGCTCAAAGGCAGTGAAAGACTAGAATCAGATAATTGGAAGGGTGC
ACCCTAAGCAATGCATAGTTCTATTTTCTTTCTTTTTTTTTTTGAGACAGAGTTTCCCTCTTGTCACACAGGCTGGAGCGCAGTGGTGCA
ATCTTGGCTCATTGCAACCTCTGCCTCCCGGGTTCAAGTGATTCTCCTGACTCAGCCTCCTGAGTAGCTGGGATTACAGGCGCATGCCAC
CACAACTGGCTAATTTTTGTATTTTTAGTAGATACAGGGTTTCACTGTGTTGGCCAGGTTGGTCTCATACTCCTGACCTCAGGTGATCCA
CCCGCCTCGGCCTCCCAAAATGTTGGGATTACAGGCGTCAGCCACCACGCCCGGCCCCAATGCATAGTTTTTTACTGAAGACAACCAGAA
TCTCTGTTGCTTATTCCAAATTTCCTTCCACCACTTGTCCATCCAGCAGAGCCACTTTTAAAATAGGACACAGGCAGAAATTTAAAGGAG
TCAATATCTCATGGTGAAAAGTGAATCCTGAGGGTTAGAGCATCCACCAGGTGCCCTAGGTAAGGGCCAGCCACTCTGGGAGGCAGCCCG
GGGCACTCACTGTCCTCTCAGTAGTAAATGAAATCACTCAGGCCATGTCTGCTACCCAGAGAGCCTGAGTGTCCTCAAATGCTTGTTCTG
CCTCTCCATCCACTCCTGCAGACACCTCAGTGGCTGCATCCCAAACCGCTGAACTTTGCTTCTCTTTCTCCAACCCCCAATTCCACCCAC
ATCCAAAACTGCTCTGCCCCCTATTCCCATCTCAGCTGAGGGTACTATCATCCACCCTGTGGCCACATCCAGGAATGTGTGTATCACCTG
GGCTCTGAGGATGACATCAGCTCTTCTAAGTCAACAGAATGTCGGGTCTGTTCTAAAAGTCTCATCTGACAAGGAGATCTTTAAGGCTTT
ACTCCCTTAAAGGCTTTACTCCCATCATGATGGGATAACCATCATGATGGATTTCAGTGTCATTCTGTCTTTTTCTTCGGAATGATTCCT
GGGACTCGCCTTGTTTGCAACATGTGCATTGAAATATCTTTTCAACATAACTTTGTTCTTAATTGTGTTTACTTCCTTTCTCTGTGAATC
TCAGTGATTCCTGGAAGCTGTGGTTGGTGGGGGATGGGGTGGGAGGACTTTGGTAGTATAAAAGAGTACCTGCAATGAATGTTCTAAGAA
ACTGGAGTGTTGGGGTCCTCCAGCCCTTGGCTGGTAAACTCTCCACTCCTTCCTCTTTGCAACACAATTCTCATAACTGGCAAAGGTGTG
CATGTAAAATTTGTGACTGTAGTCTGAGGTTTTTTTTCCCTGTACAATTCCGCCTTCCCCCCTGTAAGCCTGTACCAGGAGAGGTCTCAG
CTGCCTTGGAGGCGGTGAGACACGTGGGTGCTCACTGTGGCCCTCAAGGGTGAGGCTGGCACTGGGGCATCTGGGGCCAGAAGTCCTCCT
TTAGTCCCAAGTCTCTGCCACTCAAGTGCATCAGTGAGAGGTCCTCATAGAAAATCTACTGTGGGCACAAAGCTGCCAGGCTGATGGGGG
TGGGGAGCAAACGAACACCCTTTTCCCCTTTTACACCAGAGGAAAGAGACTTAGACTGAGGAACTTGCCTGCTGCCAGACAGCTGGGAGG
TGGTAGAACCGGGCTTACAGCCCAGGGTTTCCACTCTAGGAACTCTTCTCCCTTCCTCTGATGACACTAACTCGCAGGCCATGATCAATG
AGCAACGATGTAGGCAGGCACTGACGAGGCACAGCAGGAAGGCAGCTCAGTGCCCATGACGGCCAGGAACTGGGTACCATTTCCTCAGCA
AAATGGGATAGTAACTCCCACACTGCAGCTACGCACTTGGGCAGTGGTTCACAAGGCCAGCAGCCACAACATCACCCCAGACCAGCAGCA
GCTGCAGCATTACCCCCAGCACTTGTTAAAAGATGCAAATTCAGGCCAGGTGTGGTGGCTCGTGCCTGTAATCCCAGTACTTTGGGAAGC
CAAGGCGGGTGGGTCACCTGAGGTCAGGAGTTCGAGACCAGCCTGGCCAATGTGGTGAAACCCTGTCTCTACTAAAAATACAAAAAATGA
CCCGGGCATGGTTGTGGGCGCCTGTAATCCCAGCTACCCAGGAGACCGAGGCAGGAGAATCACTTGAACCCGGGAGGCAGAGGTTGCAGT
CAGCCGAGATTGTGCCATTACACTCCAGCCTGGGCAACAAGAGCGAAACTCTGTTTCAATAAATAAATAAAAATGCAAATTGTATGCCCC
TTCCTTCAGGCCTATGGGACCAAAAACTGGGATGGGGCCCAATAAAATGTTTTAACCAGCCCTTCGGTGGTTACAGAAGGATAGAGCCAG
AATAGACTAACCACTGTAACAAACATTACCTATACTTGGGAGGCTTTGAAAAATGTTTATTTAGCCGGGTGCGGTGGCTCACGCCTGTAA
TCCCAACACTTTGGGAGGCTGAGGCGGGCGGATCACGAGGTCAGGAGATTGAGACCAGCCTGGCTAACACAGTGAAACCCCGTCTCTACT
AAAAATACAAAAAATTAGCCAGGTGTGGTGGCAGGTGCCTGTAGTCCCAGCTACTCTGGAGGCTGAGGCAGTAGAATTTCTTGAACCCAG
GAGGCGGGGCTTGCAGTAAGTCGAGATCACGCCACTGCACTCCAGCCTGGGTGACAGAGTGAGACTCCATCTCAAAAAAAAAAAAAAAGG
AAAGAAAAATGTTTATTTTTTTGCTCATGCCACAGTCTCTGGTAGTTGCTGGGAACTAGGGTGGGGGATTCTCTGCTCCACACAGTCTTT
CATGGACCCAGGTTCCTTTCCTGTTGTGGGTCCAGCCTCCTGTAGCTGTTGGAGGCATCTCTAGTCAGCTGGTGGTTGGGGAAGAGGTGA
GGATCAGGGAGGGAAGATGGAGAGTACTCTGCTTGTTCTCACATTCTGCTGGCCAGAACTCACAAGCCACCTGAAATGATGCAAAGGTCT
AGCTGTGTGTGTAGGAGAAAGAAGAGAGGCCAGATATTGGAAGACAGCAGTGGTCTGTGCCCCAGGCCCCATGGTTTAGGGAAGTGAACC
TTGGCACTGGATTTCCTGGCTTTCTAAATCTCCCTTTATAGGGAACTTAGGGCCCAGTCTGTGGTGGGTGGATTTGCCTGGTTCACAGCC
TCTGGTCAGCCTTCTTTCTGCTCCACAGGGCGGCCTGGAGATGGTGGGCTCCTTGTCACACTGGTTGGGGATGTGGGCTCCATGGGGCCA
GAGATGTGTGTGCTCTGTGTTCAGATTAAGGGACAGACGGCACATGAATTCCTTCAGTGCCCTCCAGATTTGGTCACTGGGGAGGGGTAG
GCTGAGCAGTAGCTCTTGGGTCTGTAGTAGTGTGACCCTGGAAGGACTGTCCAGCTGAAAACAAGAGCCTGGGGCGTGGGGAGGGGAGGG
GTTACTCAGGGTTCCATGAGACCTGGGTTTAAGTCCTGGATCCATCATTAGCAGCTATGTGAACTTATGCCTCACTTTCCTCAAATATGA
ACTTGAGATAATGAAATTACCTTCCTCATAATACTGTTCTAAGAATTGAATGAGGAAAGGTTTACAATTCGGCCCTGGTTGTTCCACTGG
GGAGGGAACAGAGATTGGGGGCACAGGGCTCCCCTGGCCTGGGGGAGTCTGGCTCACTCAAGTTCTCAGTCATTTGCAAGGCAAGGACCC
TGCTTCTCCTTGCTCTGGGTCCGAGTAGTCTCAAGCCCAGTGGGCAGGGCCTGTGGTGTGGATGGACTCGTCTGCAGTGAGTCAGGCAGC
AGGCAGAGCTGGCAGGCTGTGTGGTCTCTAGTGGGTACCAGGGGACCTGGGAGGGCCTTGTGGGAGGTTGTCCACGGTGTGAGCCAGTTT
GCCATCTGGGGTCCTGGAGTTCCCTCCCGCCCTTTGAGTTAAAAAGAGTCAGTCCTGGGCTGAGACTTAATTGCGCTAGTGCTGAGTGAC
CTTGTGTCAGGGGAAATCGGATGGGGCAAAGTGTTTTTTAATTAGCAGGACTCACTGACCTTTCCTTCACTGTCAGCAACTTCTCACAGG
GAGGCAGAGCAAGGGGGGCTGGAGCCCCGCATCTCTCTAATGGAGCCTATGTCCAACAAGGAGGTGGATGGCTGGATTCAGGGCCCTGGG
AGGACTTCATGTGGGAAGCAGACCTCAGGAAGGGCCCTTAGTGATGGTGTGGGCCAGGGTTCTCACCTCCTTAGTCTCCTGTCCTGTCCA
TCTCCGCAGATCCTAGGCAAAAGAAGCGGAGAAACACTCAAGCCACTGGGGTGGTTAGGGCACACTGGTGGCAACTGTTTAAAACCTTAA
CTAAAACAAGGTTAAGCAAAAGGAGTTTACAGGCTCTCATAGATGGGAAGGATGTGGGAGGGTCACAGACTGAGAGGAACCAGGGCTGTG
GCTGCTGGAAGGAGCCTCACCACCGCCAGTGTGTTTCCTCCCCGTCGTCGGCATCTCTGCTTCTCTCTGCACGCCAGCAGCTCTCTCTTA
GGGCACGCAGACCTTTCCTCTGCAGGGGAACACGAGTGCCGGCAGCCCCGAGTTAGTGACTATCATAGAAACTCAGTGTATTTCTCTCTT
GTTTATCATTCCGAGTCCTGAGTCACAGGCTTGTCCAGCACTCAAGACTTTTTCTTTTCTCTATTTTTTGAAACGGATTCTCGCTCTGTC
CCCCAGGCTGGAGTGCAGTGGCCCGATTTTGGGTGCAAGCGATTCTCCTGCCTCAACCTCCCGAGTAGCTGGGACTACAGGTGTGCGCCA
CCACATCCAGCTAATTTTTGTATTTTTAGTAGAGACGGAGTTTCACTATGTTGGCCAGGCTGGTTTCAAACTCCTGACCTCCCGCCGGCC
TCAGCCTCCCAAAGTGCTGGGATTACAGGCATGAGCCACCACGCCTGGCCAAGATTTTTTCTTTTAAACCTGGAGTATGGAGATGCTCAC
TAGGCAGACAGAATCAGCCACCACAGCCCACTCCCTCAGCCAGTATTACTTTGACTAAGTTAGTGAGGAACCAGGCCCCAGATTAAGAAG
CAGAACTCACACTGTCATCTGCTGTGTGCCTGGCTGGCTCATGCATACCTTGTCTATCTAATGTGGACCAAAGCCCTGTGGCACACCCTG
CTGGTTACCCCCAGTGGTTACCCTGGCACAGAGGAGGAAAGGGAGTCGTGGGAGGGAGAAGGACTTCCCTGGGAGGTCTCTGGGCTGGCA
AGTTGGGTGACACAGGTCCGGTTGGCTGCAAGCCTGGGCTCTGCTGTTGTAATCATAAATGTGTGTGTGTGTACAGTTGTTTACAATGTC
AGCATGGGTGTCCTTGTTTGTTAGAGATACATGCCACTGCTCCCATCATGAGGAAAATCCCAAGCCCTCCCCATGATTTTTGCCAGTTTC
TGGGGACTCATGCTCCTGGCAGCCCATGTGTCCCCAACTCCTGTGTCCTTTAGGGACCTCTGTTGAGCCCTGCCTCTATTCTGGCAGAAT
TAGAGAAAATTCTTTAAAAAAACAATAAAGTTTAAATTCATTTAAAAAAATAATAAAAAATCTCACAGCATGAGTTTTGATGAGATTTGG
GGCAAGGTGGGCCACAACCTTGGGTTGTATGGCCACCTCCCCCTCTTCTTCCCCTGTTGTCTCTGCAGCTCAGAAACCCCAATTTCCTGG
CCTGTGTTATGTGGAGGAGCTGAGCTCACCCCCTACAGCTTCATCTCCAAACCTAGCAAGGATCCTGCCCAGATCAGGAGATCCTCCTTT
TAACAGAAGTTATTTACACTCCTTAGAAAGCAGTGGGGGTGGAACGATTCTTTTTCCTGATGCAGAGATGTAAAACTGGGACATTGCTAC
ACATAATATTTTAAACCTGTCTTCCCTCTTACCAACGAACACATCACTAGCACCATCTATGCCAATACATTTCTCAACATCAATTTCAGT
GGCTGTATTACATTTTATCCTACGGATGTGCTCTCATTTATAATCTAAACCACTTTTATTGAACACATCAGTTATTCTGAAATTTTCAGT
GTTATGATGGATGTTGCAGTAATTATTCTTATATATGCACAGAACCCCCAGAGGACATGACTACTGAAGGCTGTGCTGGCAGGATCACAG
GTAAGGATCTAGCAAATTGTCCCAGCTTCATTGACTGAGCTTTCATCCTTGTTGCACTACTTTGAGCTGCCATTTTGATCATATAATAAT
GATTTAGTAGAGCTCTTTTTTGGTTCAACCTACCTGTTCTTGTATCAGAACTGAAATGTTTGATTTTATAAATTTGAATAGTGGCACAAT
ATAGAGTTCACTATTCCTCAATATTTTCAAGGCTGTTTCTTATCTGTTCATTCTTTTGGTTAACTTGGGAATTATTTTATCAAGTCTCTC
TACTTCCCAATTTCCTTTCACCTTTGGCTCGAAATGATATTCAATGTATACATTAACTTGAGTTACATTTTGCTGCATAATGCTTGAGTT
ACATTTTGAGTATTACGTGTTACTCATAATACATATTGAGTTACATTTTGCTGCATAATACATTATCCCCAAGTTTAACACCTTAAAGCA
GCACATATATATCTCATACCCTTCTGAGGGTCAGGAATCTAGAAGCAGCTTAGCTGGGTGACTGTGGCTCTGGGTCTCTCATGAGGCTGC
AGTGAAACTGTTGGCCAGGGCTGGAGGATCCCTTCCAACCTCACTCCATGACTGTTGGTGGGAGGCTTCAGTTCTCCACCTGGTTCTCAC
AATATAATTTCCCCCAGAGTGAGTTATCAGAGAGAGTGTGCAACCAGTAATCTGTTAGAATATGTCACGTCTGTCATATTTGATTGGTCA
CTCAGACCAACCCTAATAGATGCGAGAGTGACTATGCAAGGGTGTGAGTTCCAGGAGGAAAGCATCATTGGAACCATCTTGGAGACTGGC
TAATACACAGATAAATGGCACATCTGACAATATGGCATCTTTCTGAGTGTCAGTGTGGTGTGTTCCTATATGAACTTAATGCTATTAAAC
TTAATTAAATTGTAGGTATGCTCTCAGTGAAGATTTTTACTTTTACATTACAGGTTTCCACACTGTTAAATTCATTCCAAGTATTTCATA
CATGCTGTTCCTATTATGAAAGGATCTTTTTTTTCACATGGCATTTTCTAAGTAGTTGTTGCATTCATATAGGAGATGCTATTGATTTTG
ACACCCATAATTTTTCAGTGGAGACAAGGCAGAAACTACTCCAGACTCTCACCTGCTGTTGCTGATCCTTACATGGTGGCTGTGCCAGGC
TCAGCCGCGCTGAGATGACAGGGCTGTCTGGCCATCATTGGTCATATGGACTTCAGATTTGAAAGGATTTTATGTAGAAGCAGAGTGCCT
GATAGGACTCTCCGGGACCCCCATTTCTGCCCTGCTTGGCTCCCACTGGCAAGGCTGGCTCAGTTCCTGTCACCTTCTCCTGGACTTTGG
CCAGAGTCCACTGGCTGTTTCCCCTGCCTCCTGCTCTCCCAGTGCCCTCTCCACACCAGTGCCAGAGCTGCTTCTAAGAGATGCCTCAAA
GCCCGCTTCCAGCTTAGGAACCCCAGGGAACATGGATGGTTTCTCCATTGCCACTTCCTAGCCTTCCTGGCATAGGAAGGTCTGGTTTGC
CTGCAGGTCCCTCTCTGGGGGGGTCCCTGCTCCATAGATGCTGAGGCTCCAGAAGTCTGTTCTTTTATATCACATTTGAAAACCTTTGAA

>55722_55722_3_MTMR10-TSPAN14_MTMR10_chr15_31266517_ENST00000563714_TSPAN14_chr10_82264482_ENST00000429989_length(amino acids)=387AA_BP=144
MARRKLTDDKINSEPKIKKLEPVLLPGEIVVNEVNFVRKCIATDTSQYDLWGKLICSNFKISFITDDPMPLQKFHYRNLLLGEHDVPLTC
IEQIVTVNDHKRKQKVLGPNQKLKFNPTELIIYCKDFRIVRFRFDESGPESAKKLAGVVFLGVGLWAWSEKGVLSDLTKVTRMHGIDPVV
LVLMVGVVMFTLGFAGCVGALRENICLLNFFCGTIVLIFFLELAVAVLAFLFQDWVRDRFREFFESNIKSYRDDIDLQNLIDSLQKANQC
CGAYGPEDWDLNVYFNCSGASYSREKCGVPFSCCVPDPAQKVVNTQCGYDVRIQLKSKWDESIFTKGCIQALESWLPRNIYIVAGVFIAI

--------------------------------------------------------------

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Fusion Gene PPI Analysis for MTMR10-TSPAN14


check button Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in

ChiPPI page.


check button Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160)
HgeneHgene's interactorsTgeneTgene's interactors


check button - Retained PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenStill interaction with


check button - Lost PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


check button - Retained PPIs, but lost function due to frame-shift fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


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Related Drugs for MTMR10-TSPAN14


check button Drugs targeting genes involved in this fusion gene.
(DrugBank Version 5.1.8 2021-05-08)
PartnerGeneUniProtAccDrugBank IDDrug nameDrug activityDrug typeDrug status

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Related Diseases for MTMR10-TSPAN14


check button Diseases associated with fusion partners.
(DisGeNet 4.0)
PartnerGeneDisease IDDisease name# pubmedsSource