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	Fusion Gene Summary
	Fusion Gene ORF analysis
	Fusion Genomic Features
	Fusion Protein Features
	Fusion Gene Sequence
	Fusion Gene PPI analysis
	Related Drugs
	Related Diseases

Fusion gene:MTSS1-TATDN1 (FusionGDB2 ID:55925)

Fusion Gene Summary for MTSS1-TATDN1

Fusion gene summary

Fusion gene information	Fusion gene name: MTSS1-TATDN1
	Fusion gene ID: 55925
		Hgene	Tgene
	Gene symbol	MTSS1	TATDN1
	Gene ID	9788	83940
	Gene name	MTSS I-BAR domain containing 1	TatD DNase domain containing 1
	Synonyms	MIM\|MIMA\|MIMB	CDA11
	Cytomap	8q24.13	8q24.13
	Type of gene	protein-coding	protein-coding
	Description	protein MTSS 1MTSS1, I-BAR domain containingmetastasis suppressor 1metastasis suppressor YGL-1metastasis suppressor protein 1missing in metastasis protein	putative deoxyribonuclease TATDN1hepatocarcinoma high expression protein
	Modification date	20200313	20200313
	UniProtAcc	O43312	.
	Ensembl transtripts involved in fusion gene	ENST00000325064, ENST00000378017, ENST00000518547, ENST00000354184, ENST00000395508, ENST00000431961, ENST00000523587, ENST00000524090,	ENST00000517678, ENST00000521546, ENST00000605953, ENST00000276692, ENST00000519548,
Fusion gene scores	* DoF score	12 X 13 X 9=1404	7 X 4 X 5=140
	# samples	17	7
	** MAII score	log2(17/1404*10)=-3.04593628416686 possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs). DoF>8 and MAII<0	log2(7/140*10)=-1 possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs). DoF>8 and MAII<0
Context	PubMed: MTSS1 [Title/Abstract] AND TATDN1 [Title/Abstract] AND fusion [Title/Abstract]
Most frequent breakpoint	MTSS1(125711767)-TATDN1(125500937), # samples:2 TATDN1(125551265)-MTSS1(125580777), # samples:2
Anticipated loss of major functional domain due to fusion event.	MTSS1-TATDN1 seems lost the major protein functional domain in Hgene partner, which is a essential gene due to the frame-shifted ORF. MTSS1-TATDN1 seems lost the major protein functional domain in Hgene partner, which is a tumor suppressor due to the frame-shifted ORF. TATDN1-MTSS1 seems lost the major protein functional domain in Tgene partner, which is a essential gene due to the frame-shifted ORF. TATDN1-MTSS1 seems lost the major protein functional domain in Tgene partner, which is a tumor suppressor due to the frame-shifted ORF.

* DoF score (Degree of Frequency) = # partners X # break points X # cancer types
** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)

Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez

Partner

Gene

GO ID

GO term

PubMed ID

Fusion gene breakpoints across MTSS1 (5'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.

Fusion gene breakpoints across TATDN1 (3'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.

Fusion gene information from two resources (ChiTars 5.0 and ChimerDB 4.0)
* All genome coordinats were lifted-over on hg19.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.

Source	Disease	Sample	Hgene	Hchr	Hbp	Hstrand	Tgene	Tchr	Tbp	Tstrand
ChimerDB4	BLCA	TCGA-FD-A3N5-01A	MTSS1	chr8	125711767	-	TATDN1	chr8	125500937	-

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Fusion Gene ORF analysis for MTSS1-TATDN1

Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.

ORF	Henst	Tenst	Hgene	Hchr	Hbp	Hstrand	Tgene	Tchr	Tbp	Tstrand
5CDS-intron	ENST00000325064	ENST00000517678	MTSS1	chr8	125711767	-	TATDN1	chr8	125500937	-
5CDS-intron	ENST00000325064	ENST00000521546	MTSS1	chr8	125711767	-	TATDN1	chr8	125500937	-
5CDS-intron	ENST00000325064	ENST00000605953	MTSS1	chr8	125711767	-	TATDN1	chr8	125500937	-
5CDS-intron	ENST00000378017	ENST00000517678	MTSS1	chr8	125711767	-	TATDN1	chr8	125500937	-
5CDS-intron	ENST00000378017	ENST00000521546	MTSS1	chr8	125711767	-	TATDN1	chr8	125500937	-
5CDS-intron	ENST00000378017	ENST00000605953	MTSS1	chr8	125711767	-	TATDN1	chr8	125500937	-
5CDS-intron	ENST00000518547	ENST00000517678	MTSS1	chr8	125711767	-	TATDN1	chr8	125500937	-
5CDS-intron	ENST00000518547	ENST00000521546	MTSS1	chr8	125711767	-	TATDN1	chr8	125500937	-
5CDS-intron	ENST00000518547	ENST00000605953	MTSS1	chr8	125711767	-	TATDN1	chr8	125500937	-
5UTR-3CDS	ENST00000354184	ENST00000276692	MTSS1	chr8	125711767	-	TATDN1	chr8	125500937	-
5UTR-3CDS	ENST00000354184	ENST00000519548	MTSS1	chr8	125711767	-	TATDN1	chr8	125500937	-
5UTR-intron	ENST00000354184	ENST00000517678	MTSS1	chr8	125711767	-	TATDN1	chr8	125500937	-
5UTR-intron	ENST00000354184	ENST00000521546	MTSS1	chr8	125711767	-	TATDN1	chr8	125500937	-
5UTR-intron	ENST00000354184	ENST00000605953	MTSS1	chr8	125711767	-	TATDN1	chr8	125500937	-
Frame-shift	ENST00000325064	ENST00000276692	MTSS1	chr8	125711767	-	TATDN1	chr8	125500937	-
Frame-shift	ENST00000378017	ENST00000276692	MTSS1	chr8	125711767	-	TATDN1	chr8	125500937	-
Frame-shift	ENST00000518547	ENST00000276692	MTSS1	chr8	125711767	-	TATDN1	chr8	125500937	-
In-frame	ENST00000325064	ENST00000519548	MTSS1	chr8	125711767	-	TATDN1	chr8	125500937	-
In-frame	ENST00000378017	ENST00000519548	MTSS1	chr8	125711767	-	TATDN1	chr8	125500937	-
In-frame	ENST00000518547	ENST00000519548	MTSS1	chr8	125711767	-	TATDN1	chr8	125500937	-
intron-3CDS	ENST00000395508	ENST00000276692	MTSS1	chr8	125711767	-	TATDN1	chr8	125500937	-
intron-3CDS	ENST00000395508	ENST00000519548	MTSS1	chr8	125711767	-	TATDN1	chr8	125500937	-
intron-3CDS	ENST00000431961	ENST00000276692	MTSS1	chr8	125711767	-	TATDN1	chr8	125500937	-
intron-3CDS	ENST00000431961	ENST00000519548	MTSS1	chr8	125711767	-	TATDN1	chr8	125500937	-
intron-3CDS	ENST00000523587	ENST00000276692	MTSS1	chr8	125711767	-	TATDN1	chr8	125500937	-
intron-3CDS	ENST00000523587	ENST00000519548	MTSS1	chr8	125711767	-	TATDN1	chr8	125500937	-
intron-3CDS	ENST00000524090	ENST00000276692	MTSS1	chr8	125711767	-	TATDN1	chr8	125500937	-
intron-3CDS	ENST00000524090	ENST00000519548	MTSS1	chr8	125711767	-	TATDN1	chr8	125500937	-
intron-intron	ENST00000395508	ENST00000517678	MTSS1	chr8	125711767	-	TATDN1	chr8	125500937	-
intron-intron	ENST00000395508	ENST00000521546	MTSS1	chr8	125711767	-	TATDN1	chr8	125500937	-
intron-intron	ENST00000395508	ENST00000605953	MTSS1	chr8	125711767	-	TATDN1	chr8	125500937	-
intron-intron	ENST00000431961	ENST00000517678	MTSS1	chr8	125711767	-	TATDN1	chr8	125500937	-
intron-intron	ENST00000431961	ENST00000521546	MTSS1	chr8	125711767	-	TATDN1	chr8	125500937	-
intron-intron	ENST00000431961	ENST00000605953	MTSS1	chr8	125711767	-	TATDN1	chr8	125500937	-
intron-intron	ENST00000523587	ENST00000517678	MTSS1	chr8	125711767	-	TATDN1	chr8	125500937	-
intron-intron	ENST00000523587	ENST00000521546	MTSS1	chr8	125711767	-	TATDN1	chr8	125500937	-
intron-intron	ENST00000523587	ENST00000605953	MTSS1	chr8	125711767	-	TATDN1	chr8	125500937	-
intron-intron	ENST00000524090	ENST00000517678	MTSS1	chr8	125711767	-	TATDN1	chr8	125500937	-
intron-intron	ENST00000524090	ENST00000521546	MTSS1	chr8	125711767	-	TATDN1	chr8	125500937	-
intron-intron	ENST00000524090	ENST00000605953	MTSS1	chr8	125711767	-	TATDN1	chr8	125500937	-

ORFfinder result based on the fusion transcript sequence of in-frame fusion genes.

Henst	Tenst	Hgene	Hchr	Hbp	Hstrand	Tgene	Tchr	Tbp	Tstrand	Seq length (transcript)	BP loci (transcript)	Predicted start (transcript)	Predicted stop (transcript)	Seq length (amino acids)
ENST00000378017	MTSS1	chr8	125711767	-	ENST00000519548	TATDN1	chr8	125500937	-	455	271	63	287	74
ENST00000518547	MTSS1	chr8	125711767	-	ENST00000519548	TATDN1	chr8	125500937	-	866	682	707	285	140
ENST00000325064	MTSS1	chr8	125711767	-	ENST00000519548	TATDN1	chr8	125500937	-	710	526	385	143	80

DeepORF prediction of the coding potential based on the fusion transcript sequence of in-frame fusion genes. DeepORF is a coding potential classifier based on convolutional neural network by comparing the real Ribo-seq data. If the no-coding score < 0.5 and coding score > 0.5, then the in-frame fusion transcript is predicted as being likely translated.

Henst	Tenst	Hgene	Hchr	Hbp	Hstrand	Tgene	Tchr	Tbp	Tstrand	No-coding score	Coding score
ENST00000378017	ENST00000519548	MTSS1	chr8	125711767	-	TATDN1	chr8	125500937	-	0.08105304	0.9189469
ENST00000518547	ENST00000519548	MTSS1	chr8	125711767	-	TATDN1	chr8	125500937	-	0.16041526	0.8395847
ENST00000325064	ENST00000519548	MTSS1	chr8	125711767	-	TATDN1	chr8	125500937	-	0.12910444	0.87089556

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Fusion Genomic Features for MTSS1-TATDN1

FusionAI prediction of the potential fusion gene breakpoint based on the pre-mature RNA sequence context (+/- 5kb of individual partner genes, total 20kb length sequence). FusionAI is a fusion gene breakpoint classifier based on convolutional neural network by comparing the fusion positive and negative sequence context of ~ 20K fusion gene data. From here, we can have the relative potentency of the 20K genomic sequence how individual sequnce will be likely used as the gene fusion breakpoints.

Hgene

Hchr

Hbp

Hstrand

Tgene

Tchr

Tbp

Tstrand

1-p

p (fusion gene breakpoint)

Distribution of 44 human genomic features loci across 20kb length fusion breakpoint regions. We integrated a total of 44 different types of human genomic feature loci information across five big categories including virus integration sites, repeats, structural variants, chromatin states, and gene expression regulation. More details are in help page.

Distribution of 44 human genomic features loci across 20kb length fusion breakpoint regions that are ovelapped with the top 1% feature importance score regions. More details are in help page.

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Fusion Protein Features for MTSS1-TATDN1

Four levels of functional features of fusion genes
Go to FGviewer search page for the most frequent breakpoint (https://ccsmweb.uth.edu/FGviewer/chr8:125711767/chr8:125500937)
- FGviewer provides the online visualization of the retention search of the protein functional features across DNA, RNA, protein, and pathological levels.
- How to search
1. Put your fusion gene symbol.
2. Press the tab key until there will be shown the breakpoint information filled.
4. Go down and press 'Search' tab twice.
4. Go down to have the hyperlink of the search result.
5. Click the hyperlink.
6. See the FGviewer result for your fusion gene.

Main function of each fusion partner protein. (from UniProt)

Hgene	Tgene
MTSS1 O43312	.
FUNCTION: May be related to cancer progression or tumor metastasis in a variety of organ sites, most likely through an interaction with the actin cytoskeleton.	FUNCTION: Transcriptional activator which is required for calcium-dependent dendritic growth and branching in cortical neurons. Recruits CREB-binding protein (CREBBP) to nuclear bodies. Component of the CREST-BRG1 complex, a multiprotein complex that regulates promoter activation by orchestrating a calcium-dependent release of a repressor complex and a recruitment of an activator complex. In resting neurons, transcription of the c-FOS promoter is inhibited by BRG1-dependent recruitment of a phospho-RB1-HDAC1 repressor complex. Upon calcium influx, RB1 is dephosphorylated by calcineurin, which leads to release of the repressor complex. At the same time, there is increased recruitment of CREBBP to the promoter by a CREST-dependent mechanism, which leads to transcriptional activation. The CREST-BRG1 complex also binds to the NR2B promoter, and activity-dependent induction of NR2B expression involves a release of HDAC1 and recruitment of CREBBP (By similarity). {ECO:0000250}.

Retention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at
download page

* Minus value of BPloci means that the break pointn is located before the CDS.

- In-frame and retained protein feature among the 13 regional features.

Partner

Gene

Hbp

Tbp

ENST

Strand

BPexon

TotalExon

Protein feature loci

*BPloci

TotalLen

Protein feature

Protein feature note

- In-frame and not-retained protein feature among the 13 regional features.

Partner

Gene

Hbp

Tbp

ENST

Strand

BPexon

TotalExon

Protein feature loci

*BPloci

TotalLen

Protein feature

Protein feature note

Hgene

MTSS1

chr8:125711767

chr8:125500937

ENST00000354184

108_155

474.0

Coiled coil

Ontology_term=ECO:0000255

Hgene

MTSS1

chr8:125711767

chr8:125500937

ENST00000378017

108_155

731.0

Coiled coil

Ontology_term=ECO:0000255

Hgene

MTSS1

chr8:125711767

chr8:125500937

ENST00000431961

108_155

474.0

Coiled coil

Ontology_term=ECO:0000255

Hgene

MTSS1

chr8:125711767

chr8:125500937

ENST00000518547

108_155

756.0

Coiled coil

Ontology_term=ECO:0000255

Hgene

MTSS1

chr8:125711767

chr8:125500937

ENST00000354184

238_359

474.0

Compositional bias

Note=Ser-rich

Hgene

MTSS1

chr8:125711767

chr8:125500937

ENST00000354184

608_726

474.0

Compositional bias

Note=Pro-rich

Hgene

MTSS1

chr8:125711767

chr8:125500937

ENST00000378017

238_359

731.0

Compositional bias

Note=Ser-rich

Hgene

MTSS1

chr8:125711767

chr8:125500937

ENST00000378017

608_726

731.0

Compositional bias

Note=Pro-rich

Hgene

MTSS1

chr8:125711767

chr8:125500937

ENST00000431961

238_359

474.0

Compositional bias

Note=Ser-rich

Hgene

MTSS1

chr8:125711767

chr8:125500937

ENST00000431961

608_726

474.0

Compositional bias

Note=Pro-rich

Hgene

MTSS1

chr8:125711767

chr8:125500937

ENST00000518547

238_359

756.0

Compositional bias

Note=Ser-rich

Hgene

MTSS1

chr8:125711767

chr8:125500937

ENST00000518547

608_726

756.0

Compositional bias

Note=Pro-rich

Hgene

MTSS1

chr8:125711767

chr8:125500937

ENST00000354184

1_250

474.0

Domain

IMD

Hgene

MTSS1

chr8:125711767

chr8:125500937

ENST00000354184

727_744

474.0

Domain

WH2

Hgene

MTSS1

chr8:125711767

chr8:125500937

ENST00000378017

1_250

731.0

Domain

IMD

Hgene

MTSS1

chr8:125711767

chr8:125500937

ENST00000378017

727_744

731.0

Domain

WH2

Hgene

MTSS1

chr8:125711767

chr8:125500937

ENST00000431961

1_250

474.0

Domain

IMD

Hgene

MTSS1

chr8:125711767

chr8:125500937

ENST00000431961

727_744

474.0

Domain

WH2

Hgene

MTSS1

chr8:125711767

chr8:125500937

ENST00000518547

1_250

756.0

Domain

IMD

Hgene

MTSS1

chr8:125711767

chr8:125500937

ENST00000518547

727_744

756.0

Domain

WH2

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Fusion Gene Sequence for MTSS1-TATDN1

For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. To have fusion amino acid sequence, we ran ORFfinder and chose the longest ORF among the all predicted ones.

>55925_55925_1_MTSS1-TATDN1_MTSS1_chr8_125711767_ENST00000325064_TATDN1_chr8_125500937_ENST00000519548_length(transcript)=710nt_BP=526nt
CAAGATGGGCTTTGCCGTTTCCGTAGTGGGCACCAGTGGTGGCCTGATTGTCAGTCTTCTCCCGGCATTTTTAAGGCCAGGAGCCGAGCG
CTGCTTGTAGGCGAATACCCTACAGAGCGGTTTGGCTTTTTAAATTACTGTTATTATTTTGGGCAGAGAACAGTCGGTCTGGTGCACCCC
GTCCTCGCTGCAGAAGAGGCTGCGAGTCCGAGGTGGGTCTCTCGGAAGGTGAAATTCCTTCTGGGGTGAGCGAGCCCCGGCCCCGCGCGC
AGTCCAGCGGCCCCGCGTGTGTGCCCTCGCCCTGCCGGAGCCGGGAAAATGGAGGCTGTGATTGAGAAGGAATGCAGCGCGCTCGGAGGC
CTCTTCCAGACCATCATCAGCGACATGAAGGGGAGCTATCCAGTTTGGGAAGATTTCATAAACAAAGCAGGAAAGCTGCAGTCCCAGCTT
CGGACAACAGTAGTAGCAGCAGCTGCCTTCTTGGACGCCTTTCAGAAAGTGGCTGACATGGCCACCAACACACGTGTCAAATATTGGAGA
TAATGTCAGCAGTGAGAGATGAGGATCCACTGGAATTAGCCAATACACTATATAACAATACTATTAAAGTATTTTTTCCTGGAATATAAT

>55925_55925_1_MTSS1-TATDN1_MTSS1_chr8_125711767_ENST00000325064_TATDN1_chr8_125500937_ENST00000519548_length(amino acids)=80AA_BP=

--------------------------------------------------------------
>55925_55925_2_MTSS1-TATDN1_MTSS1_chr8_125711767_ENST00000378017_TATDN1_chr8_125500937_ENST00000519548_length(transcript)=455nt_BP=271nt
CCCGGCCCCGCGCGCAGTCCAGCGGCCCCGCGTGTGTGCCCTCGCCCTGCCGGAGCCGGGAAAATGGAGGCTGTGATTGAGAAGGAATGC
AGCGCGCTCGGAGGCCTCTTCCAGACCATCATCAGCGACATGAAGGGGAGCTATCCAGTTTGGGAAGATTTCATAAACAAAGCAGGAAAG
CTGCAGTCCCAGCTTCGGACAACAGTAGTAGCAGCAGCTGCCTTCTTGGACGCCTTTCAGAAAGTGGCTGACATGGCCACCAACACACGT
GTCAAATATTGGAGATAATGTCAGCAGTGAGAGATGAGGATCCACTGGAATTAGCCAATACACTATATAACAATACTATTAAAGTATTTT
TTCCTGGAATATAATTGGTATATGTCTTCCACTTTCCATCATGTATGTAAAATTTCATAGTAAAACTTCCTGATAGTTTCAATAAAGAAA

>55925_55925_2_MTSS1-TATDN1_MTSS1_chr8_125711767_ENST00000378017_TATDN1_chr8_125500937_ENST00000519548_length(amino acids)=74AA_BP=

--------------------------------------------------------------
>55925_55925_3_MTSS1-TATDN1_MTSS1_chr8_125711767_ENST00000518547_TATDN1_chr8_125500937_ENST00000519548_length(transcript)=866nt_BP=682nt
GCGGCCGCAGCTGCGAGCAACAGATCCGGACGCCGCGAGCTGACCCGCTCTGCTGTTGGGCGATTTTTTTTTAATTGCAGAAAAATTTAT
TAAATTGGAAAATCTTGCGTTTTTCAATGGCGCTGGCCCCGGGTCAGCGGGCGATTTTCTCTGCATCAAGATGGGCTTTGCCGTTTCCGT
AGTGGGCACCAGTGGTGGCCTGATTGTCAGTCTTCTCCCGGCATTTTTAAGGCCAGGAGCCGAGCGCTGCTTGTAGGCGAATACCCTACA
GAGCGGTTTGGCTTTTTAAATTACTGTTATTATTTTGGGCAGAGAACAGTCGGTCTGGTGCACCCCGTCCTCGCTGCAGAAGAGGCTGCG
AGTCCGAGGTGGGTCTCTCGGAAGGTGAAATTCCTTCTGGGGTGAGCGAGCCCCGGCCCCGCGCGCAGTCCAGCGGCCCCGCGTGTGTGC
CCTCGCCCTGCCGGAGCCGGGAAAATGGAGGCTGTGATTGAGAAGGAATGCAGCGCGCTCGGAGGCCTCTTCCAGACCATCATCAGCGAC
ATGAAGGGGAGCTATCCAGTTTGGGAAGATTTCATAAACAAAGCAGGAAAGCTGCAGTCCCAGCTTCGGACAACAGTAGTAGCAGCAGCT
GCCTTCTTGGACGCCTTTCAGAAAGTGGCTGACATGGCCACCAACACACGTGTCAAATATTGGAGATAATGTCAGCAGTGAGAGATGAGG
ATCCACTGGAATTAGCCAATACACTATATAACAATACTATTAAAGTATTTTTTCCTGGAATATAATTGGTATATGTCTTCCACTTTCCAT

>55925_55925_3_MTSS1-TATDN1_MTSS1_chr8_125711767_ENST00000518547_TATDN1_chr8_125500937_ENST00000519548_length(amino acids)=140AA_BP=1
MLTLSPIFDTCVGGHVSHFLKGVQEGSCCYYCCPKLGLQLSCFVYEIFPNWIAPLHVADDGLEEASERAAFLLNHSLHFPGSGRARAHTR

--------------------------------------------------------------

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Fusion Gene PPI Analysis for MTSS1-TATDN1

Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in
ChiPPI page.

Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160)

Hgene

Hgene's interactors

Tgene

Tgene's interactors

- Retained PPIs in in-frame fusion.

Partner

Gene

Hbp

Tbp

ENST

Strand

BPexon

TotalExon

Protein feature loci

*BPloci

TotalLen

Still interaction with

- Lost PPIs in in-frame fusion.

Partner

Gene

Hbp

Tbp

ENST

Strand

BPexon

TotalExon

Protein feature loci

*BPloci

TotalLen

Interaction lost with

- Retained PPIs, but lost function due to frame-shift fusion.

Partner

Gene

Hbp

Tbp

ENST

Strand

BPexon

TotalExon

Protein feature loci

*BPloci

TotalLen

Interaction lost with

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Related Drugs for MTSS1-TATDN1

Drugs targeting genes involved in this fusion gene.
(DrugBank Version 5.1.8 2021-05-08)

Partner

Gene

UniProtAcc

DrugBank ID

Drug name

Drug activity

Drug type

Drug status

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Related Diseases for MTSS1-TATDN1

Diseases associated with fusion partners.
(DisGeNet 4.0)

Partner

Gene

Disease ID

Disease name

# pubmeds

Source