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Center for Computational Systems Medicine
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Fusion Gene Summary

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Fusion Gene ORF analysis

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Fusion Genomic Features

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Fusion Protein Features

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Fusion Gene Sequence

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Fusion Gene PPI analysis

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Related Drugs

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Related Diseases

Fusion gene:MYH11-MYLK (FusionGDB2 ID:56300)

Fusion Gene Summary for MYH11-MYLK

check button Fusion gene summary
Fusion gene informationFusion gene name: MYH11-MYLK
Fusion gene ID: 56300
HgeneTgene
Gene symbol

MYH11

MYLK

Gene ID

4629

4638

Gene namemyosin heavy chain 11myosin light chain kinase
SynonymsAAT4|FAA4|SMHC|SMMHCAAT7|KRP|MLCK|MLCK1|MLCK108|MLCK210|MMIHS|MSTP083|MYLK1|smMLCK
Cytomap

16p13.11

3q21.1

Type of geneprotein-codingprotein-coding
Descriptionmyosin-11epididymis secretory sperm binding proteinmyosin heavy chain, smooth muscle isoformmyosin, heavy chain 11, smooth musclemyosin, heavy polypeptide 11, smooth musclemyosin light chain kinase, smooth musclekinase-related proteinmyosin, light polypeptide kinasesmooth muscle myosin light chain kinasetelokin
Modification date2020032220200320
UniProtAcc

P35749

Q86YV6

Ensembl transtripts involved in fusion geneENST00000300036, ENST00000396324, 
ENST00000452625, ENST00000576790, 
ENST00000573908, 		ENST00000346322, 
ENST00000354792, ENST00000418370, 
ENST00000475616, ENST00000510775, 
ENST00000578202, ENST00000583087, 
ENST00000359169, ENST00000360304, 
ENST00000360772, 
Fusion gene scores* DoF score31 X 31 X 8=768814 X 15 X 4=840
# samples 3215
** MAII scorelog2(32/7688*10)=-4.58646452588639
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0		log2(15/840*10)=-2.48542682717024
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0
Context

PubMed: MYH11 [Title/Abstract] AND MYLK [Title/Abstract] AND fusion [Title/Abstract]

Most frequent breakpointMYH11(15809021)-MYLK(123383105), # samples:1
MYLK(123333009)-MYH11(15797744), # samples:1
Anticipated loss of major functional domain due to fusion event.MYH11-MYLK seems lost the major protein functional domain in Hgene partner, which is a CGC due to the frame-shifted ORF.
MYH11-MYLK seems lost the major protein functional domain in Tgene partner, which is a IUPHAR drug target due to the frame-shifted ORF.
MYH11-MYLK seems lost the major protein functional domain in Tgene partner, which is a kinase due to the frame-shifted ORF.
* DoF score (Degree of Frequency) = # partners X # break points X # cancer types
** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)

check button Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez
PartnerGeneGO IDGO termPubMed ID
TgeneMYLK

GO:0030335

positive regulation of cell migration

19826488

TgeneMYLK

GO:0051928

positive regulation of calcium ion transport

16284075

TgeneMYLK

GO:0071476

cellular hypotonic response

11976941

TgeneMYLK

GO:0090303

positive regulation of wound healing

15825080


check buttonFusion gene breakpoints across MYH11 (5'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check buttonFusion gene breakpoints across MYLK (3'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check button Fusion gene information from two resources (ChiTars 5.0 and ChimerDB 4.0)
* All genome coordinats were lifted-over on hg19.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
SourceDiseaseSampleHgeneHchrHbpHstrandTgeneTchrTbpTstrand
ChimerDB4SARCTCGA-3B-A9HR-01AMYH11chr16

15809021

-MYLKchr3

123383105

-


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Fusion Gene ORF analysis for MYH11-MYLK

check button Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
ORFHenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrand
5CDS-intronENST00000300036ENST00000346322MYH11chr16

15809021

-MYLKchr3

123383105

-
5CDS-intronENST00000300036ENST00000354792MYH11chr16

15809021

-MYLKchr3

123383105

-
5CDS-intronENST00000300036ENST00000418370MYH11chr16

15809021

-MYLKchr3

123383105

-
5CDS-intronENST00000300036ENST00000475616MYH11chr16

15809021

-MYLKchr3

123383105

-
5CDS-intronENST00000300036ENST00000510775MYH11chr16

15809021

-MYLKchr3

123383105

-
5CDS-intronENST00000300036ENST00000578202MYH11chr16

15809021

-MYLKchr3

123383105

-
5CDS-intronENST00000300036ENST00000583087MYH11chr16

15809021

-MYLKchr3

123383105

-
5CDS-intronENST00000396324ENST00000346322MYH11chr16

15809021

-MYLKchr3

123383105

-
5CDS-intronENST00000396324ENST00000354792MYH11chr16

15809021

-MYLKchr3

123383105

-
5CDS-intronENST00000396324ENST00000418370MYH11chr16

15809021

-MYLKchr3

123383105

-
5CDS-intronENST00000396324ENST00000475616MYH11chr16

15809021

-MYLKchr3

123383105

-
5CDS-intronENST00000396324ENST00000510775MYH11chr16

15809021

-MYLKchr3

123383105

-
5CDS-intronENST00000396324ENST00000578202MYH11chr16

15809021

-MYLKchr3

123383105

-
5CDS-intronENST00000396324ENST00000583087MYH11chr16

15809021

-MYLKchr3

123383105

-
5CDS-intronENST00000452625ENST00000346322MYH11chr16

15809021

-MYLKchr3

123383105

-
5CDS-intronENST00000452625ENST00000354792MYH11chr16

15809021

-MYLKchr3

123383105

-
5CDS-intronENST00000452625ENST00000418370MYH11chr16

15809021

-MYLKchr3

123383105

-
5CDS-intronENST00000452625ENST00000475616MYH11chr16

15809021

-MYLKchr3

123383105

-
5CDS-intronENST00000452625ENST00000510775MYH11chr16

15809021

-MYLKchr3

123383105

-
5CDS-intronENST00000452625ENST00000578202MYH11chr16

15809021

-MYLKchr3

123383105

-
5CDS-intronENST00000452625ENST00000583087MYH11chr16

15809021

-MYLKchr3

123383105

-
5CDS-intronENST00000576790ENST00000346322MYH11chr16

15809021

-MYLKchr3

123383105

-
5CDS-intronENST00000576790ENST00000354792MYH11chr16

15809021

-MYLKchr3

123383105

-
5CDS-intronENST00000576790ENST00000418370MYH11chr16

15809021

-MYLKchr3

123383105

-
5CDS-intronENST00000576790ENST00000475616MYH11chr16

15809021

-MYLKchr3

123383105

-
5CDS-intronENST00000576790ENST00000510775MYH11chr16

15809021

-MYLKchr3

123383105

-
5CDS-intronENST00000576790ENST00000578202MYH11chr16

15809021

-MYLKchr3

123383105

-
5CDS-intronENST00000576790ENST00000583087MYH11chr16

15809021

-MYLKchr3

123383105

-
Frame-shiftENST00000300036ENST00000359169MYH11chr16

15809021

-MYLKchr3

123383105

-
Frame-shiftENST00000300036ENST00000360304MYH11chr16

15809021

-MYLKchr3

123383105

-
Frame-shiftENST00000300036ENST00000360772MYH11chr16

15809021

-MYLKchr3

123383105

-
Frame-shiftENST00000396324ENST00000359169MYH11chr16

15809021

-MYLKchr3

123383105

-
Frame-shiftENST00000396324ENST00000360304MYH11chr16

15809021

-MYLKchr3

123383105

-
Frame-shiftENST00000396324ENST00000360772MYH11chr16

15809021

-MYLKchr3

123383105

-
In-frameENST00000452625ENST00000359169MYH11chr16

15809021

-MYLKchr3

123383105

-
In-frameENST00000452625ENST00000360304MYH11chr16

15809021

-MYLKchr3

123383105

-
In-frameENST00000452625ENST00000360772MYH11chr16

15809021

-MYLKchr3

123383105

-
In-frameENST00000576790ENST00000359169MYH11chr16

15809021

-MYLKchr3

123383105

-
In-frameENST00000576790ENST00000360304MYH11chr16

15809021

-MYLKchr3

123383105

-
In-frameENST00000576790ENST00000360772MYH11chr16

15809021

-MYLKchr3

123383105

-
intron-3CDSENST00000573908ENST00000359169MYH11chr16

15809021

-MYLKchr3

123383105

-
intron-3CDSENST00000573908ENST00000360304MYH11chr16

15809021

-MYLKchr3

123383105

-
intron-3CDSENST00000573908ENST00000360772MYH11chr16

15809021

-MYLKchr3

123383105

-
intron-intronENST00000573908ENST00000346322MYH11chr16

15809021

-MYLKchr3

123383105

-
intron-intronENST00000573908ENST00000354792MYH11chr16

15809021

-MYLKchr3

123383105

-
intron-intronENST00000573908ENST00000418370MYH11chr16

15809021

-MYLKchr3

123383105

-
intron-intronENST00000573908ENST00000475616MYH11chr16

15809021

-MYLKchr3

123383105

-
intron-intronENST00000573908ENST00000510775MYH11chr16

15809021

-MYLKchr3

123383105

-
intron-intronENST00000573908ENST00000578202MYH11chr16

15809021

-MYLKchr3

123383105

-
intron-intronENST00000573908ENST00000583087MYH11chr16

15809021

-MYLKchr3

123383105

-

check buttonORFfinder result based on the fusion transcript sequence of in-frame fusion genes.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandSeq length
(transcript)		BP loci
(transcript)		Predicted start
(transcript)		Predicted stop
(transcript)		Seq length
(amino acids)
ENST00000452625MYH11chr1615809021-ENST00000360772MYLKchr3123383105-1153957226174822473
ENST00000452625MYH11chr1615809021-ENST00000359169MYLKchr3123383105-929057226174822473
ENST00000452625MYH11chr1615809021-ENST00000360304MYLKchr3123383105-944357226176352524
ENST00000576790MYH11chr1615809021-ENST00000360772MYLKchr3123383105-1154057238374832466
ENST00000576790MYH11chr1615809021-ENST00000359169MYLKchr3123383105-929157238374832466
ENST00000576790MYH11chr1615809021-ENST00000360304MYLKchr3123383105-944457238376362517

check buttonDeepORF prediction of the coding potential based on the fusion transcript sequence of in-frame fusion genes. DeepORF is a coding potential classifier based on convolutional neural network by comparing the real Ribo-seq data. If the no-coding score < 0.5 and coding score > 0.5, then the in-frame fusion transcript is predicted as being likely translated.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandNo-coding scoreCoding score
ENST00000452625ENST00000360772MYH11chr1615809021-MYLKchr3123383105-0.004466480.99553347
ENST00000452625ENST00000359169MYH11chr1615809021-MYLKchr3123383105-0.0099582940.99004173
ENST00000452625ENST00000360304MYH11chr1615809021-MYLKchr3123383105-0.0080109320.9919891
ENST00000576790ENST00000360772MYH11chr1615809021-MYLKchr3123383105-0.0045799560.9954201
ENST00000576790ENST00000359169MYH11chr1615809021-MYLKchr3123383105-0.0102048970.98979515
ENST00000576790ENST00000360304MYH11chr1615809021-MYLKchr3123383105-0.0082100280.99178994

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Fusion Genomic Features for MYH11-MYLK


check buttonFusionAI prediction of the potential fusion gene breakpoint based on the pre-mature RNA sequence context (+/- 5kb of individual partner genes, total 20kb length sequence). FusionAI is a fusion gene breakpoint classifier based on convolutional neural network by comparing the fusion positive and negative sequence context of ~ 20K fusion gene data. From here, we can have the relative potentency of the 20K genomic sequence how individual sequnce will be likely used as the gene fusion breakpoints.
HgeneHchrHbpHstrandTgeneTchrTbpTstrand1-pp (fusion gene breakpoint)

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions. We integrated a total of 44 different types of human genomic feature loci information across five big categories including virus integration sites, repeats, structural variants, chromatin states, and gene expression regulation. More details are in help page.
genomic feature

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions that are ovelapped with the top 1% feature importance score regions. More details are in help page.

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Fusion Protein Features for MYH11-MYLK


check button Four levels of functional features of fusion genes
Go to FGviewer search page for the most frequent breakpoint (https://ccsmweb.uth.edu/FGviewer/chr16:15809021/chr3:123383105)
- FGviewer provides the online visualization of the retention search of the protein functional features across DNA, RNA, protein, and pathological levels.
- How to search
1. Put your fusion gene symbol.
2. Press the tab key until there will be shown the breakpoint information filled.
4. Go down and press 'Search' tab twice.
4. Go down to have the hyperlink of the search result.
5. Click the hyperlink.
6. See the FGviewer result for your fusion gene.
FGviewer

check buttonMain function of each fusion partner protein. (from UniProt)
HgeneTgene
MYH11

P35749

MYLK

Q86YV6

FUNCTION: Muscle contraction.

check buttonRetention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at

download page


* Minus value of BPloci means that the break pointn is located before the CDS.
- In-frame and retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneMYH11chr16:15809021chr3:123383105ENST00000300036-394131_8118711973.0DomainMyosin N-terminal SH3-like
HgeneMYH11chr16:15809021chr3:123383105ENST00000300036-3941786_81518711973.0DomainIQ
HgeneMYH11chr16:15809021chr3:123383105ENST00000300036-394185_78318711973.0DomainMyosin motor
HgeneMYH11chr16:15809021chr3:123383105ENST00000396324-404231_8118781980.0DomainMyosin N-terminal SH3-like
HgeneMYH11chr16:15809021chr3:123383105ENST00000396324-4042786_81518781980.0DomainIQ
HgeneMYH11chr16:15809021chr3:123383105ENST00000396324-404285_78318781980.0DomainMyosin motor
HgeneMYH11chr16:15809021chr3:123383105ENST00000452625-404331_8118782132.0DomainMyosin N-terminal SH3-like
HgeneMYH11chr16:15809021chr3:123383105ENST00000452625-4043786_81518782132.0DomainIQ
HgeneMYH11chr16:15809021chr3:123383105ENST00000452625-404385_78318782132.0DomainMyosin motor
HgeneMYH11chr16:15809021chr3:123383105ENST00000576790-394231_8118711912.6666666666667DomainMyosin N-terminal SH3-like
HgeneMYH11chr16:15809021chr3:123383105ENST00000576790-3942786_81518711912.6666666666667DomainIQ
HgeneMYH11chr16:15809021chr3:123383105ENST00000576790-394285_78318711912.6666666666667DomainMyosin motor
HgeneMYH11chr16:15809021chr3:123383105ENST00000300036-3941178_18518711973.0Nucleotide bindingATP
HgeneMYH11chr16:15809021chr3:123383105ENST00000396324-4042178_18518781980.0Nucleotide bindingATP
HgeneMYH11chr16:15809021chr3:123383105ENST00000452625-4043178_18518782132.0Nucleotide bindingATP
HgeneMYH11chr16:15809021chr3:123383105ENST00000576790-3942178_18518711912.6666666666667Nucleotide bindingATP
HgeneMYH11chr16:15809021chr3:123383105ENST00000300036-3941661_68318711973.0RegionActin-binding
HgeneMYH11chr16:15809021chr3:123383105ENST00000300036-3941762_77618711973.0RegionActin-binding
HgeneMYH11chr16:15809021chr3:123383105ENST00000396324-4042661_68318781980.0RegionActin-binding
HgeneMYH11chr16:15809021chr3:123383105ENST00000396324-4042762_77618781980.0RegionActin-binding
HgeneMYH11chr16:15809021chr3:123383105ENST00000452625-4043661_68318782132.0RegionActin-binding
HgeneMYH11chr16:15809021chr3:123383105ENST00000452625-4043762_77618782132.0RegionActin-binding
HgeneMYH11chr16:15809021chr3:123383105ENST00000576790-3942661_68318711912.6666666666667RegionActin-binding
HgeneMYH11chr16:15809021chr3:123383105ENST00000576790-3942762_77618711912.6666666666667RegionActin-binding
TgeneMYLKchr16:15809021chr3:123383105ENST0000034632220331906_191412081846.0Compositional biasNote=Poly-Glu
TgeneMYLKchr16:15809021chr3:123383105ENST0000035916921331906_191412771864.0Compositional biasNote=Poly-Glu
TgeneMYLKchr16:15809021chr3:123383105ENST0000036030421341906_191412771915.0Compositional biasNote=Poly-Glu
TgeneMYLKchr16:15809021chr3:123383105ENST0000036077222341906_191412771864.0Compositional biasNote=Poly-Glu
TgeneMYLKchr16:15809021chr3:123383105ENST00000418370031906_19140155.0Compositional biasNote=Poly-Glu
TgeneMYLKchr16:15809021chr3:123383105ENST0000047561618311906_191412771915.0Compositional biasNote=Poly-Glu
TgeneMYLKchr16:15809021chr3:123383105ENST00000583087041906_19140155.0Compositional biasNote=Poly-Glu
TgeneMYLKchr16:15809021chr3:123383105ENST0000034632220331238_132612081846.0DomainNote=Ig-like C2-type 8
TgeneMYLKchr16:15809021chr3:123383105ENST0000034632220331334_142612081846.0DomainFibronectin type-III
TgeneMYLKchr16:15809021chr3:123383105ENST0000034632220331464_171912081846.0DomainProtein kinase
TgeneMYLKchr16:15809021chr3:123383105ENST0000034632220331809_189812081846.0DomainNote=Ig-like C2-type 9
TgeneMYLKchr16:15809021chr3:123383105ENST0000035916921331334_142612771864.0DomainFibronectin type-III
TgeneMYLKchr16:15809021chr3:123383105ENST0000035916921331464_171912771864.0DomainProtein kinase
TgeneMYLKchr16:15809021chr3:123383105ENST0000035916921331809_189812771864.0DomainNote=Ig-like C2-type 9
TgeneMYLKchr16:15809021chr3:123383105ENST0000036030421341334_142612771915.0DomainFibronectin type-III
TgeneMYLKchr16:15809021chr3:123383105ENST0000036030421341464_171912771915.0DomainProtein kinase
TgeneMYLKchr16:15809021chr3:123383105ENST0000036030421341809_189812771915.0DomainNote=Ig-like C2-type 9
TgeneMYLKchr16:15809021chr3:123383105ENST0000036077222341334_142612771864.0DomainFibronectin type-III
TgeneMYLKchr16:15809021chr3:123383105ENST0000036077222341464_171912771864.0DomainProtein kinase
TgeneMYLKchr16:15809021chr3:123383105ENST0000036077222341809_189812771864.0DomainNote=Ig-like C2-type 9
TgeneMYLKchr16:15809021chr3:123383105ENST00000418370031098_11860155.0DomainNote=Ig-like C2-type 7
TgeneMYLKchr16:15809021chr3:123383105ENST00000418370031238_13260155.0DomainNote=Ig-like C2-type 8
TgeneMYLKchr16:15809021chr3:123383105ENST00000418370031334_14260155.0DomainFibronectin type-III
TgeneMYLKchr16:15809021chr3:123383105ENST00000418370031464_17190155.0DomainProtein kinase
TgeneMYLKchr16:15809021chr3:123383105ENST0000041837003161_2490155.0DomainNote=Ig-like C2-type 2
TgeneMYLKchr16:15809021chr3:123383105ENST00000418370031809_18980155.0DomainNote=Ig-like C2-type 9
TgeneMYLKchr16:15809021chr3:123383105ENST000004183700333_1220155.0DomainNote=Ig-like C2-type 1
TgeneMYLKchr16:15809021chr3:123383105ENST0000041837003414_5030155.0DomainNote=Ig-like C2-type 3
TgeneMYLKchr16:15809021chr3:123383105ENST0000041837003514_5990155.0DomainNote=Ig-like C2-type 4
TgeneMYLKchr16:15809021chr3:123383105ENST0000041837003620_7110155.0DomainNote=Ig-like C2-type 5
TgeneMYLKchr16:15809021chr3:123383105ENST0000041837003721_8210155.0DomainNote=Ig-like C2-type 6
TgeneMYLKchr16:15809021chr3:123383105ENST0000047561618311334_142612771915.0DomainFibronectin type-III
TgeneMYLKchr16:15809021chr3:123383105ENST0000047561618311464_171912771915.0DomainProtein kinase
TgeneMYLKchr16:15809021chr3:123383105ENST0000047561618311809_189812771915.0DomainNote=Ig-like C2-type 9
TgeneMYLKchr16:15809021chr3:123383105ENST00000583087041098_11860155.0DomainNote=Ig-like C2-type 7
TgeneMYLKchr16:15809021chr3:123383105ENST00000583087041238_13260155.0DomainNote=Ig-like C2-type 8
TgeneMYLKchr16:15809021chr3:123383105ENST00000583087041334_14260155.0DomainFibronectin type-III
TgeneMYLKchr16:15809021chr3:123383105ENST00000583087041464_17190155.0DomainProtein kinase
TgeneMYLKchr16:15809021chr3:123383105ENST0000058308704161_2490155.0DomainNote=Ig-like C2-type 2
TgeneMYLKchr16:15809021chr3:123383105ENST00000583087041809_18980155.0DomainNote=Ig-like C2-type 9
TgeneMYLKchr16:15809021chr3:123383105ENST000005830870433_1220155.0DomainNote=Ig-like C2-type 1
TgeneMYLKchr16:15809021chr3:123383105ENST0000058308704414_5030155.0DomainNote=Ig-like C2-type 3
TgeneMYLKchr16:15809021chr3:123383105ENST0000058308704514_5990155.0DomainNote=Ig-like C2-type 4
TgeneMYLKchr16:15809021chr3:123383105ENST0000058308704620_7110155.0DomainNote=Ig-like C2-type 5
TgeneMYLKchr16:15809021chr3:123383105ENST0000058308704721_8210155.0DomainNote=Ig-like C2-type 6
TgeneMYLKchr16:15809021chr3:123383105ENST0000034632220331470_147812081846.0Nucleotide bindingATP
TgeneMYLKchr16:15809021chr3:123383105ENST0000035916921331470_147812771864.0Nucleotide bindingATP
TgeneMYLKchr16:15809021chr3:123383105ENST0000036030421341470_147812771915.0Nucleotide bindingATP
TgeneMYLKchr16:15809021chr3:123383105ENST0000036077222341470_147812771864.0Nucleotide bindingATP
TgeneMYLKchr16:15809021chr3:123383105ENST00000418370031470_14780155.0Nucleotide bindingATP
TgeneMYLKchr16:15809021chr3:123383105ENST0000047561618311470_147812771915.0Nucleotide bindingATP
TgeneMYLKchr16:15809021chr3:123383105ENST00000583087041470_14780155.0Nucleotide bindingATP
TgeneMYLKchr16:15809021chr3:123383105ENST0000034632220331711_177412081846.0RegionNote=Calmodulin-binding
TgeneMYLKchr16:15809021chr3:123383105ENST0000035916921331711_177412771864.0RegionNote=Calmodulin-binding
TgeneMYLKchr16:15809021chr3:123383105ENST0000036030421341711_177412771915.0RegionNote=Calmodulin-binding
TgeneMYLKchr16:15809021chr3:123383105ENST0000036077222341711_177412771864.0RegionNote=Calmodulin-binding
TgeneMYLKchr16:15809021chr3:123383105ENST00000418370031061_14600155.0RegionActin-binding (calcium/calmodulin-insensitive)
TgeneMYLKchr16:15809021chr3:123383105ENST00000418370031711_17740155.0RegionNote=Calmodulin-binding
TgeneMYLKchr16:15809021chr3:123383105ENST0000041837003868_9980155.0RegionNote=5 X 28 AA approximate tandem repeats
TgeneMYLKchr16:15809021chr3:123383105ENST0000041837003923_9630155.0RegionActin-binding (calcium/calmodulin-sensitive)
TgeneMYLKchr16:15809021chr3:123383105ENST0000041837003948_9630155.0RegionCalmodulin-binding
TgeneMYLKchr16:15809021chr3:123383105ENST0000041837003999_10630155.0RegionNote=6 X 12 AA approximate tandem repeats
TgeneMYLKchr16:15809021chr3:123383105ENST0000047561618311711_177412771915.0RegionNote=Calmodulin-binding
TgeneMYLKchr16:15809021chr3:123383105ENST00000583087041061_14600155.0RegionActin-binding (calcium/calmodulin-insensitive)
TgeneMYLKchr16:15809021chr3:123383105ENST00000583087041711_17740155.0RegionNote=Calmodulin-binding
TgeneMYLKchr16:15809021chr3:123383105ENST0000058308704868_9980155.0RegionNote=5 X 28 AA approximate tandem repeats
TgeneMYLKchr16:15809021chr3:123383105ENST0000058308704923_9630155.0RegionActin-binding (calcium/calmodulin-sensitive)
TgeneMYLKchr16:15809021chr3:123383105ENST0000058308704948_9630155.0RegionCalmodulin-binding
TgeneMYLKchr16:15809021chr3:123383105ENST0000058308704999_10630155.0RegionNote=6 X 12 AA approximate tandem repeats
TgeneMYLKchr16:15809021chr3:123383105ENST00000418370031004_10150155.0RepeatNote=2-2
TgeneMYLKchr16:15809021chr3:123383105ENST00000418370031016_10270155.0RepeatNote=2-3
TgeneMYLKchr16:15809021chr3:123383105ENST00000418370031028_10390155.0RepeatNote=2-4
TgeneMYLKchr16:15809021chr3:123383105ENST00000418370031040_10510155.0RepeatNote=2-5
TgeneMYLKchr16:15809021chr3:123383105ENST00000418370031052_10630155.0RepeatNote=2-6
TgeneMYLKchr16:15809021chr3:123383105ENST0000041837003868_8950155.0RepeatNote=1-1
TgeneMYLKchr16:15809021chr3:123383105ENST0000041837003896_9230155.0RepeatNote=1-2
TgeneMYLKchr16:15809021chr3:123383105ENST0000041837003924_9510155.0RepeatNote=1-3
TgeneMYLKchr16:15809021chr3:123383105ENST0000041837003952_9790155.0RepeatNote=1-4
TgeneMYLKchr16:15809021chr3:123383105ENST0000041837003980_9980155.0RepeatNote=1-5%3B truncated
TgeneMYLKchr16:15809021chr3:123383105ENST0000041837003999_10030155.0RepeatNote=2-1%3B truncated
TgeneMYLKchr16:15809021chr3:123383105ENST00000583087041004_10150155.0RepeatNote=2-2
TgeneMYLKchr16:15809021chr3:123383105ENST00000583087041016_10270155.0RepeatNote=2-3
TgeneMYLKchr16:15809021chr3:123383105ENST00000583087041028_10390155.0RepeatNote=2-4
TgeneMYLKchr16:15809021chr3:123383105ENST00000583087041040_10510155.0RepeatNote=2-5
TgeneMYLKchr16:15809021chr3:123383105ENST00000583087041052_10630155.0RepeatNote=2-6
TgeneMYLKchr16:15809021chr3:123383105ENST0000058308704868_8950155.0RepeatNote=1-1
TgeneMYLKchr16:15809021chr3:123383105ENST0000058308704896_9230155.0RepeatNote=1-2
TgeneMYLKchr16:15809021chr3:123383105ENST0000058308704924_9510155.0RepeatNote=1-3
TgeneMYLKchr16:15809021chr3:123383105ENST0000058308704952_9790155.0RepeatNote=1-4
TgeneMYLKchr16:15809021chr3:123383105ENST0000058308704980_9980155.0RepeatNote=1-5%3B truncated
TgeneMYLKchr16:15809021chr3:123383105ENST0000058308704999_10030155.0RepeatNote=2-1%3B truncated

- In-frame and not-retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneMYH11chr16:15809021chr3:123383105ENST00000300036-3941844_193418711973.0Coiled coilOntology_term=ECO:0000255
HgeneMYH11chr16:15809021chr3:123383105ENST00000396324-4042844_193418781980.0Coiled coilOntology_term=ECO:0000255
HgeneMYH11chr16:15809021chr3:123383105ENST00000452625-4043844_193418782132.0Coiled coilOntology_term=ECO:0000255
HgeneMYH11chr16:15809021chr3:123383105ENST00000576790-3942844_193418711912.6666666666667Coiled coilOntology_term=ECO:0000255
HgeneMYH11chr16:15809021chr3:123383105ENST00000300036-39411935_197218711973.0RegionNote=C-terminal
HgeneMYH11chr16:15809021chr3:123383105ENST00000396324-40421935_197218781980.0RegionNote=C-terminal
HgeneMYH11chr16:15809021chr3:123383105ENST00000452625-40431935_197218782132.0RegionNote=C-terminal
HgeneMYH11chr16:15809021chr3:123383105ENST00000576790-39421935_197218711912.6666666666667RegionNote=C-terminal
TgeneMYLKchr16:15809021chr3:123383105ENST0000034632220331098_118612081846.0DomainNote=Ig-like C2-type 7
TgeneMYLKchr16:15809021chr3:123383105ENST000003463222033161_24912081846.0DomainNote=Ig-like C2-type 2
TgeneMYLKchr16:15809021chr3:123383105ENST00000346322203333_12212081846.0DomainNote=Ig-like C2-type 1
TgeneMYLKchr16:15809021chr3:123383105ENST000003463222033414_50312081846.0DomainNote=Ig-like C2-type 3
TgeneMYLKchr16:15809021chr3:123383105ENST000003463222033514_59912081846.0DomainNote=Ig-like C2-type 4
TgeneMYLKchr16:15809021chr3:123383105ENST000003463222033620_71112081846.0DomainNote=Ig-like C2-type 5
TgeneMYLKchr16:15809021chr3:123383105ENST000003463222033721_82112081846.0DomainNote=Ig-like C2-type 6
TgeneMYLKchr16:15809021chr3:123383105ENST0000035916921331098_118612771864.0DomainNote=Ig-like C2-type 7
TgeneMYLKchr16:15809021chr3:123383105ENST0000035916921331238_132612771864.0DomainNote=Ig-like C2-type 8
TgeneMYLKchr16:15809021chr3:123383105ENST000003591692133161_24912771864.0DomainNote=Ig-like C2-type 2
TgeneMYLKchr16:15809021chr3:123383105ENST00000359169213333_12212771864.0DomainNote=Ig-like C2-type 1
TgeneMYLKchr16:15809021chr3:123383105ENST000003591692133414_50312771864.0DomainNote=Ig-like C2-type 3
TgeneMYLKchr16:15809021chr3:123383105ENST000003591692133514_59912771864.0DomainNote=Ig-like C2-type 4
TgeneMYLKchr16:15809021chr3:123383105ENST000003591692133620_71112771864.0DomainNote=Ig-like C2-type 5
TgeneMYLKchr16:15809021chr3:123383105ENST000003591692133721_82112771864.0DomainNote=Ig-like C2-type 6
TgeneMYLKchr16:15809021chr3:123383105ENST0000036030421341098_118612771915.0DomainNote=Ig-like C2-type 7
TgeneMYLKchr16:15809021chr3:123383105ENST0000036030421341238_132612771915.0DomainNote=Ig-like C2-type 8
TgeneMYLKchr16:15809021chr3:123383105ENST000003603042134161_24912771915.0DomainNote=Ig-like C2-type 2
TgeneMYLKchr16:15809021chr3:123383105ENST00000360304213433_12212771915.0DomainNote=Ig-like C2-type 1
TgeneMYLKchr16:15809021chr3:123383105ENST000003603042134414_50312771915.0DomainNote=Ig-like C2-type 3
TgeneMYLKchr16:15809021chr3:123383105ENST000003603042134514_59912771915.0DomainNote=Ig-like C2-type 4
TgeneMYLKchr16:15809021chr3:123383105ENST000003603042134620_71112771915.0DomainNote=Ig-like C2-type 5
TgeneMYLKchr16:15809021chr3:123383105ENST000003603042134721_82112771915.0DomainNote=Ig-like C2-type 6
TgeneMYLKchr16:15809021chr3:123383105ENST0000036077222341098_118612771864.0DomainNote=Ig-like C2-type 7
TgeneMYLKchr16:15809021chr3:123383105ENST0000036077222341238_132612771864.0DomainNote=Ig-like C2-type 8
TgeneMYLKchr16:15809021chr3:123383105ENST000003607722234161_24912771864.0DomainNote=Ig-like C2-type 2
TgeneMYLKchr16:15809021chr3:123383105ENST00000360772223433_12212771864.0DomainNote=Ig-like C2-type 1
TgeneMYLKchr16:15809021chr3:123383105ENST000003607722234414_50312771864.0DomainNote=Ig-like C2-type 3
TgeneMYLKchr16:15809021chr3:123383105ENST000003607722234514_59912771864.0DomainNote=Ig-like C2-type 4
TgeneMYLKchr16:15809021chr3:123383105ENST000003607722234620_71112771864.0DomainNote=Ig-like C2-type 5
TgeneMYLKchr16:15809021chr3:123383105ENST000003607722234721_82112771864.0DomainNote=Ig-like C2-type 6
TgeneMYLKchr16:15809021chr3:123383105ENST0000047561618311098_118612771915.0DomainNote=Ig-like C2-type 7
TgeneMYLKchr16:15809021chr3:123383105ENST0000047561618311238_132612771915.0DomainNote=Ig-like C2-type 8
TgeneMYLKchr16:15809021chr3:123383105ENST000004756161831161_24912771915.0DomainNote=Ig-like C2-type 2
TgeneMYLKchr16:15809021chr3:123383105ENST00000475616183133_12212771915.0DomainNote=Ig-like C2-type 1
TgeneMYLKchr16:15809021chr3:123383105ENST000004756161831414_50312771915.0DomainNote=Ig-like C2-type 3
TgeneMYLKchr16:15809021chr3:123383105ENST000004756161831514_59912771915.0DomainNote=Ig-like C2-type 4
TgeneMYLKchr16:15809021chr3:123383105ENST000004756161831620_71112771915.0DomainNote=Ig-like C2-type 5
TgeneMYLKchr16:15809021chr3:123383105ENST000004756161831721_82112771915.0DomainNote=Ig-like C2-type 6
TgeneMYLKchr16:15809021chr3:123383105ENST0000034632220331061_146012081846.0RegionActin-binding (calcium/calmodulin-insensitive)
TgeneMYLKchr16:15809021chr3:123383105ENST000003463222033868_99812081846.0RegionNote=5 X 28 AA approximate tandem repeats
TgeneMYLKchr16:15809021chr3:123383105ENST000003463222033923_96312081846.0RegionActin-binding (calcium/calmodulin-sensitive)
TgeneMYLKchr16:15809021chr3:123383105ENST000003463222033948_96312081846.0RegionCalmodulin-binding
TgeneMYLKchr16:15809021chr3:123383105ENST000003463222033999_106312081846.0RegionNote=6 X 12 AA approximate tandem repeats
TgeneMYLKchr16:15809021chr3:123383105ENST0000035916921331061_146012771864.0RegionActin-binding (calcium/calmodulin-insensitive)
TgeneMYLKchr16:15809021chr3:123383105ENST000003591692133868_99812771864.0RegionNote=5 X 28 AA approximate tandem repeats
TgeneMYLKchr16:15809021chr3:123383105ENST000003591692133923_96312771864.0RegionActin-binding (calcium/calmodulin-sensitive)
TgeneMYLKchr16:15809021chr3:123383105ENST000003591692133948_96312771864.0RegionCalmodulin-binding
TgeneMYLKchr16:15809021chr3:123383105ENST000003591692133999_106312771864.0RegionNote=6 X 12 AA approximate tandem repeats
TgeneMYLKchr16:15809021chr3:123383105ENST0000036030421341061_146012771915.0RegionActin-binding (calcium/calmodulin-insensitive)
TgeneMYLKchr16:15809021chr3:123383105ENST000003603042134868_99812771915.0RegionNote=5 X 28 AA approximate tandem repeats
TgeneMYLKchr16:15809021chr3:123383105ENST000003603042134923_96312771915.0RegionActin-binding (calcium/calmodulin-sensitive)
TgeneMYLKchr16:15809021chr3:123383105ENST000003603042134948_96312771915.0RegionCalmodulin-binding
TgeneMYLKchr16:15809021chr3:123383105ENST000003603042134999_106312771915.0RegionNote=6 X 12 AA approximate tandem repeats
TgeneMYLKchr16:15809021chr3:123383105ENST0000036077222341061_146012771864.0RegionActin-binding (calcium/calmodulin-insensitive)
TgeneMYLKchr16:15809021chr3:123383105ENST000003607722234868_99812771864.0RegionNote=5 X 28 AA approximate tandem repeats
TgeneMYLKchr16:15809021chr3:123383105ENST000003607722234923_96312771864.0RegionActin-binding (calcium/calmodulin-sensitive)
TgeneMYLKchr16:15809021chr3:123383105ENST000003607722234948_96312771864.0RegionCalmodulin-binding
TgeneMYLKchr16:15809021chr3:123383105ENST000003607722234999_106312771864.0RegionNote=6 X 12 AA approximate tandem repeats
TgeneMYLKchr16:15809021chr3:123383105ENST0000047561618311061_146012771915.0RegionActin-binding (calcium/calmodulin-insensitive)
TgeneMYLKchr16:15809021chr3:123383105ENST000004756161831868_99812771915.0RegionNote=5 X 28 AA approximate tandem repeats
TgeneMYLKchr16:15809021chr3:123383105ENST000004756161831923_96312771915.0RegionActin-binding (calcium/calmodulin-sensitive)
TgeneMYLKchr16:15809021chr3:123383105ENST000004756161831948_96312771915.0RegionCalmodulin-binding
TgeneMYLKchr16:15809021chr3:123383105ENST000004756161831999_106312771915.0RegionNote=6 X 12 AA approximate tandem repeats
TgeneMYLKchr16:15809021chr3:123383105ENST0000034632220331004_101512081846.0RepeatNote=2-2
TgeneMYLKchr16:15809021chr3:123383105ENST0000034632220331016_102712081846.0RepeatNote=2-3
TgeneMYLKchr16:15809021chr3:123383105ENST0000034632220331028_103912081846.0RepeatNote=2-4
TgeneMYLKchr16:15809021chr3:123383105ENST0000034632220331040_105112081846.0RepeatNote=2-5
TgeneMYLKchr16:15809021chr3:123383105ENST0000034632220331052_106312081846.0RepeatNote=2-6
TgeneMYLKchr16:15809021chr3:123383105ENST000003463222033868_89512081846.0RepeatNote=1-1
TgeneMYLKchr16:15809021chr3:123383105ENST000003463222033896_92312081846.0RepeatNote=1-2
TgeneMYLKchr16:15809021chr3:123383105ENST000003463222033924_95112081846.0RepeatNote=1-3
TgeneMYLKchr16:15809021chr3:123383105ENST000003463222033952_97912081846.0RepeatNote=1-4
TgeneMYLKchr16:15809021chr3:123383105ENST000003463222033980_99812081846.0RepeatNote=1-5%3B truncated
TgeneMYLKchr16:15809021chr3:123383105ENST000003463222033999_100312081846.0RepeatNote=2-1%3B truncated
TgeneMYLKchr16:15809021chr3:123383105ENST0000035916921331004_101512771864.0RepeatNote=2-2
TgeneMYLKchr16:15809021chr3:123383105ENST0000035916921331016_102712771864.0RepeatNote=2-3
TgeneMYLKchr16:15809021chr3:123383105ENST0000035916921331028_103912771864.0RepeatNote=2-4
TgeneMYLKchr16:15809021chr3:123383105ENST0000035916921331040_105112771864.0RepeatNote=2-5
TgeneMYLKchr16:15809021chr3:123383105ENST0000035916921331052_106312771864.0RepeatNote=2-6
TgeneMYLKchr16:15809021chr3:123383105ENST000003591692133868_89512771864.0RepeatNote=1-1
TgeneMYLKchr16:15809021chr3:123383105ENST000003591692133896_92312771864.0RepeatNote=1-2
TgeneMYLKchr16:15809021chr3:123383105ENST000003591692133924_95112771864.0RepeatNote=1-3
TgeneMYLKchr16:15809021chr3:123383105ENST000003591692133952_97912771864.0RepeatNote=1-4
TgeneMYLKchr16:15809021chr3:123383105ENST000003591692133980_99812771864.0RepeatNote=1-5%3B truncated
TgeneMYLKchr16:15809021chr3:123383105ENST000003591692133999_100312771864.0RepeatNote=2-1%3B truncated
TgeneMYLKchr16:15809021chr3:123383105ENST0000036030421341004_101512771915.0RepeatNote=2-2
TgeneMYLKchr16:15809021chr3:123383105ENST0000036030421341016_102712771915.0RepeatNote=2-3
TgeneMYLKchr16:15809021chr3:123383105ENST0000036030421341028_103912771915.0RepeatNote=2-4
TgeneMYLKchr16:15809021chr3:123383105ENST0000036030421341040_105112771915.0RepeatNote=2-5
TgeneMYLKchr16:15809021chr3:123383105ENST0000036030421341052_106312771915.0RepeatNote=2-6
TgeneMYLKchr16:15809021chr3:123383105ENST000003603042134868_89512771915.0RepeatNote=1-1
TgeneMYLKchr16:15809021chr3:123383105ENST000003603042134896_92312771915.0RepeatNote=1-2
TgeneMYLKchr16:15809021chr3:123383105ENST000003603042134924_95112771915.0RepeatNote=1-3
TgeneMYLKchr16:15809021chr3:123383105ENST000003603042134952_97912771915.0RepeatNote=1-4
TgeneMYLKchr16:15809021chr3:123383105ENST000003603042134980_99812771915.0RepeatNote=1-5%3B truncated
TgeneMYLKchr16:15809021chr3:123383105ENST000003603042134999_100312771915.0RepeatNote=2-1%3B truncated
TgeneMYLKchr16:15809021chr3:123383105ENST0000036077222341004_101512771864.0RepeatNote=2-2
TgeneMYLKchr16:15809021chr3:123383105ENST0000036077222341016_102712771864.0RepeatNote=2-3
TgeneMYLKchr16:15809021chr3:123383105ENST0000036077222341028_103912771864.0RepeatNote=2-4
TgeneMYLKchr16:15809021chr3:123383105ENST0000036077222341040_105112771864.0RepeatNote=2-5
TgeneMYLKchr16:15809021chr3:123383105ENST0000036077222341052_106312771864.0RepeatNote=2-6
TgeneMYLKchr16:15809021chr3:123383105ENST000003607722234868_89512771864.0RepeatNote=1-1
TgeneMYLKchr16:15809021chr3:123383105ENST000003607722234896_92312771864.0RepeatNote=1-2
TgeneMYLKchr16:15809021chr3:123383105ENST000003607722234924_95112771864.0RepeatNote=1-3
TgeneMYLKchr16:15809021chr3:123383105ENST000003607722234952_97912771864.0RepeatNote=1-4
TgeneMYLKchr16:15809021chr3:123383105ENST000003607722234980_99812771864.0RepeatNote=1-5%3B truncated
TgeneMYLKchr16:15809021chr3:123383105ENST000003607722234999_100312771864.0RepeatNote=2-1%3B truncated
TgeneMYLKchr16:15809021chr3:123383105ENST0000047561618311004_101512771915.0RepeatNote=2-2
TgeneMYLKchr16:15809021chr3:123383105ENST0000047561618311016_102712771915.0RepeatNote=2-3
TgeneMYLKchr16:15809021chr3:123383105ENST0000047561618311028_103912771915.0RepeatNote=2-4
TgeneMYLKchr16:15809021chr3:123383105ENST0000047561618311040_105112771915.0RepeatNote=2-5
TgeneMYLKchr16:15809021chr3:123383105ENST0000047561618311052_106312771915.0RepeatNote=2-6
TgeneMYLKchr16:15809021chr3:123383105ENST000004756161831868_89512771915.0RepeatNote=1-1
TgeneMYLKchr16:15809021chr3:123383105ENST000004756161831896_92312771915.0RepeatNote=1-2
TgeneMYLKchr16:15809021chr3:123383105ENST000004756161831924_95112771915.0RepeatNote=1-3
TgeneMYLKchr16:15809021chr3:123383105ENST000004756161831952_97912771915.0RepeatNote=1-4
TgeneMYLKchr16:15809021chr3:123383105ENST000004756161831980_99812771915.0RepeatNote=1-5%3B truncated
TgeneMYLKchr16:15809021chr3:123383105ENST000004756161831999_100312771915.0RepeatNote=2-1%3B truncated


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Fusion Gene Sequence for MYH11-MYLK


check button For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. To have fusion amino acid sequence, we ran ORFfinder and chose the longest ORF among the all predicted ones.
>56300_56300_1_MYH11-MYLK_MYH11_chr16_15809021_ENST00000452625_MYLK_chr3_123383105_ENST00000359169_length(transcript)=9290nt_BP=5722nt
GCCTGGGAGGTGCGTCAGATCCGAGCTCGCCATCCAGTTTCCTCTCCACTAGTCCCCCCAGTTGGAGATCTGGGACCAACAAGGCACCAT
GGCGCAGAAGGGCCAACTCAGTGACGATGAGAAGTTCCTCTTTGTGGACAAAAACTTCATCAACAGCCCAGTGGCCCAGGCTGACTGGGC
CGCCAAGAGACTCGTCTGGGTCCCCTCGGAGAAGCAGGGCTTCGAGGCAGCCAGCATTAAGGAGGAGAAGGGGGATGAGGTGGTTGTGGA
GCTGGTGGAGAATGGCAAGAAGGTCACGGTTGGGAAAGATGACATCCAGAAGATGAACCCACCCAAGTTCTCCAAGGTGGAGGACATGGC
GGAGCTGACGTGCCTCAACGAAGCCTCCGTGCTACACAACCTGAGGGAGCGGTACTTCTCAGGGCTAATATATACGTACTCTGGCCTCTT
CTGCGTGGTGGTCAACCCCTATAAACACCTGCCCATCTACTCGGAGAAGATCGTCGACATGTACAAGGGCAAGAAGAGGCACGAGATGCC
GCCTCACATCTACGCCATCGCAGACACGGCCTACCGGAGCATGCTTCAAGATCGGGAGGACCAGTCCATTCTATGCACAGGCGAGTCTGG
AGCCGGGAAAACCGAAAACACCAAGAAGGTCATTCAGTACCTGGCCGTGGTGGCCTCCTCCCACAAGGGCAAGAAAGACACAAGTATCAC
GCAAGGCCCATCTTTTGCCTACGGAGAGCTGGAAAAGCAGCTTCTACAAGCAAACCCGATTCTGGAGGCTTTCGGCAACGCCAAAACAGT
GAAGAACGACAACTCCTCACGATTCGGCAAATTCATCCGCATCAACTTCGACGTCACGGGTTACATCGTGGGAGCCAACATTGAGACCTA
TCTGCTAGAAAAATCACGGGCAATTCGCCAAGCCAGAGACGAGAGGACATTCCACATCTTTTACTACATGATTGCTGGAGCCAAGGAGAA
GATGAGAAGTGACTTGCTTTTGGAGGGCTTCAACAACTACACCTTCCTCTCCAATGGCTTTGTGCCCATCCCAGCAGCCCAGGATGATGA
GATGTTCCAGGAAACCGTGGAGGCCATGGCAATCATGGGTTTCAGCGAGGAGGAGCAGCTATCCATATTGAAGGTGGTATCATCGGTCCT
GCAGCTTGGAAATATCGTCTTCAAGAAGGAAAGAAACACAGACCAGGCGTCCATGCCAGATAACACAGCTGCTCAGAAAGTTTGCCACCT
CATGGGAATTAATGTGACAGATTTCACCAGATCCATCCTCACTCCTCGTATCAAGGTTGGGCGAGATGTGGTACAGAAAGCTCAGACAAA
AGAACAGGCTGACTTTGCTGTAGAGGCTTTGGCCAAGGCAACATATGAGCGCCTTTTCCGCTGGATACTCACCCGCGTGAACAAAGCCCT
GGACAAGACCCATCGGCAAGGGGCTTCCTTCCTGGGGATCCTGGATATAGCTGGATTTGAGATCTTTGAGGTGAACTCCTTCGAGCAGCT
GTGCATCAACTACACCAACGAGAAGCTGCAGCAGCTCTTCAACCACACCATGTTCATCCTGGAGCAGGAGGAGTACCAGCGCGAGGGCAT
CGAGTGGAACTTCATCGACTTTGGGCTGGACCTACAGCCCTGCATCGAGCTCATCGAGCGACCGAACAACCCTCCAGGTGTGCTGGCCCT
GCTGGACGAGGAATGCTGGTTCCCCAAAGCCACGGACAAGTCTTTCGTGGAGAAGCTGTGCACGGAGCAGGGCAGCCACCCCAAGTTCCA
GAAGCCCAAGCAGCTCAAGGACAAGACTGAGTTCTCCATCATCCATTATGCTGGGAAGGTGGACTATAATGCGAGTGCCTGGCTGACCAA
GAATATGGACCCGCTGAATGACAACGTGACTTCCCTGCTCAATGCCTCCTCCGACAAGTTTGTGGCCGACCTGTGGAAGGACGTGGACCG
CATCGTGGGCCTGGACCAGATGGCCAAGATGACGGAGAGCTCGCTGCCCAGCGCCTCCAAGACCAAGAAGGGCATGTTCCGCACAGTGGG
GCAGCTGTACAAGGAGCAGCTGGGCAAGCTGATGACCACGCTACGCAACACCACGCCCAACTTCGTGCGCTGCATCATCCCCAACCACGA
GAAGAGGTCCGGCAAGCTGGATGCGTTCCTGGTGCTGGAGCAGCTGCGGTGCAATGGGGTGCTGGAAGGCATTCGCATCTGCCGGCAGGG
CTTCCCCAACCGGATCGTCTTCCAGGAGTTCCGCCAACGCTACGAGATCCTGGCGGCGAATGCCATCCCCAAAGGCTTCATGGACGGGAA
GCAGGCCTGCATTCTCATGATCAAAGCCCTGGAACTTGACCCCAACTTATACAGGATAGGGCAGAGCAAAATCTTCTTCCGAACTGGCGT
CCTGGCCCACCTAGAGGAGGAGCGAGATTTGAAGATCACCGATGTCATCATGGCCTTCCAGGCGATGTGTCGTGGCTACTTGGCCAGAAA
GGCTTTTGCCAAGAGGCAGCAGCAGCTGACCGCCATGAAGGTGATTCAGAGGAACTGCGCCGCCTACCTCAAGCTGCGGAACTGGCAGTG
GTGGAGGCTTTTCACCAAAGTGAAGCCACTGCTGCAGGTGACACGGCAGGAGGAGGAGATGCAGGCCAAGGAGGATGAACTGCAGAAGAC
CAAGGAGCGGCAGCAGAAGGCAGAGAATGAGCTTAAGGAGCTGGAACAGAAGCACTCGCAGCTGACCGAGGAGAAGAACCTGCTACAGGA
ACAGCTGCAGGCAGAGACAGAGCTGTATGCAGAGGCTGAGGAGATGCGGGTGCGGCTGGCGGCCAAGAAGCAGGAGCTGGAGGAGATACT
GCATGAGATGGAGGCCCGCCTGGAGGAGGAGGAAGACAGGGGCCAGCAGCTACAGGCTGAAAGGAAGAAGATGGCCCAGCAGATGCTGGA
CCTTGAAGAACAGCTGGAGGAGGAGGAAGCTGCCAGGCAGAAGCTGCAACTTGAGAAGGTCACGGCTGAGGCCAAGATCAAGAAACTGGA
GGATGAGATCCTGGTCATGGATGATCAGAACAATAAACTATCAAAAGAACGAAAACTCCTTGAGGAGAGGATTAGTGACTTAACGACAAA
TCTTGCAGAAGAGGAAGAAAAGGCCAAGAATCTTACCAAGCTGAAAAACAAGCATGAATCTATGATTTCAGAACTGGAAGTGCGGCTAAA
GAAGGAAGAGAAGAGCCGACAGGAGCTGGAGAAGCTGAAACGGAAGCTGGAGGGTGATGCCAGCGACTTCCACGAGCAGATCGCTGACCT
CCAGGCGCAGATCGCAGAGCTCAAGATGCAGCTGGCCAAGAAGGAGGAGGAGCTGCAGGCGGCCCTGGCCAGGCTTGACGATGAAATCGC
TCAGAAGAACAATGCCCTGAAGAAGATCCGGGAGCTGGAGGGCCACATCTCAGACCTCCAGGAGGACCTGGACTCAGAGCGGGCCGCCAG
GAACAAGGCTGAAAAGCAGAAGCGAGACCTCGGCGAGGAGCTGGAGGCCCTAAAGACAGAGCTGGAAGACACACTGGACAGCACAGCCAC
TCAGCAGGAGCTCAGGGCCAAGAGGGAGCAGGAGGTGACGGTGCTGAAGAAGGCCCTGGATGAAGAGACGCGGTCCCATGAGGCTCAGGT
CCAGGAGATGAGGCAGAAACACGCACAGGCGGTGGAGGAGCTCACAGAGCAGCTTGAGCAGTTCAAGAGGGCCAAGGCGAACCTAGACAA
GAATAAGCAGACGCTGGAGAAAGAGAACGCAGACCTGGCCGGGGAGCTGCGGGTCCTGGGCCAGGCCAAGCAGGAGGTGGAACATAAGAA
GAAGAAGCTGGAGGCGCAGGTGCAGGAGCTGCAGTCCAAGTGCAGCGATGGGGAGCGGGCCCGGGCGGAGCTCAATGACAAAGTCCACAA
GCTGCAGAATGAAGTTGAGAGCGTCACAGGGATGCTTAACGAGGCCGAGGGGAAGGCCATTAAGCTGGCCAAGGACGTGGCGTCCCTCAG
TTCCCAGCTCCAGGACACCCAGGAGCTGCTTCAAGAAGAAACCCGGCAGAAGCTCAACGTGTCTACGAAGCTGCGCCAGCTGGAGGAGGA
GCGGAACAGCCTGCAAGACCAGCTGGACGAGGAGATGGAGGCCAAGCAGAACCTGGAGCGCCACATCTCCACTCTCAACATCCAGCTCTC
CGACTCGAAGAAGAAGCTGCAGGACTTTGCCAGCACCGTGGAAGCTCTGGAAGAGGGGAAGAAGAGGTTCCAGAAGGAGATCGAGAACCT
CACCCAGCAGTACGAGGAGAAGGCGGCCGCTTATGATAAACTGGAAAAGACCAAGAACAGGCTTCAGCAGGAGCTGGACGACCTGGTTGT
TGATTTGGACAACCAGCGGCAACTCGTGTCCAACCTGGAAAAGAAGCAGAGGAAATTTGATCAGTTGTTAGCCGAGGAGAAAAACATCTC
TTCCAAATACGCGGATGAGAGGGACAGAGCTGAGGCAGAAGCCAGGGAGAAGGAAACCAAGGCCCTGTCCCTGGCTCGGGCCCTTGAAGA
GGCCTTGGAAGCCAAAGAGGAACTCGAGCGGACCAACAAAATGCTCAAAGCCGAAATGGAAGACCTGGTCAGCTCCAAGGATGACGTGGG
CAAGAACGTCCATGAGCTGGAGAAGTCCAAGCGGGCCCTGGAGACCCAGATGGAGGAGATGAAGACGCAGCTGGAAGAGCTGGAGGACGA
GCTGCAAGCCACGGAGGACGCCAAACTGCGGCTGGAAGTCAACATGCAGGCGCTCAAGGGCCAGTTCGAAAGGGATCTCCAAGCCCGGGA
CGAGCAGAATGAGGAGAAGAGGAGGCAACTGCAGAGACAGCTTCACGAGTATGAGACGGAACTGGAAGACGAGCGAAAGCAACGTGCCCT
GGCAGCTGCAGCAAAGAAGAAGCTGGAAGGGGACCTGAAAGACCTGGAGCTTCAGGCCGACTCTGCCATCAAGGGGAGGGAGGAAGCCAT
CAAGCAGCTACGCAAACTGCAGGCTCAGATGAAGGACTTTCAAAGAGAGCTGGAAGATGCCCGTGCCTCCAGAGATGAGATCTTTGCCAC
AGCCAAAGAGAATGAGAAGAAAGCCAAGAGCTTGGAAGCAGACCTCATGCAGCTACAAGAGGACCTCGCCGCCGCTGAGAGGGCTCGCAA
ACAAGCGGACCTCGAGAAGGAGGAACTGGCAGAGGAGCTGGCCAGTAGCCTGTCGGGAAGGAACGCACTCCAGGACGAGAAGCGCCGCCT
GGAGGCCCGGATCGCCCAGCTGGAGGAGGAGCTGGAGGAGGAGCAGGGCAACATGGAGGCCATGAGCGACCGGGTCCGCAAAGCCACACA
GCAGGCCGAGCAGCTCAGCAACGAGCTGGCCACAGAGCGCAGCACGGCCCAGAAGAATGAGAGTGCCCGGCAGCAGCTCGAGCGGCAGAA
CAAGGAGCTCCGGAGCAAGCTCCACGAGATGGAGGGGGCCGTCAAGTCCAAGTTCAAGTCCACCATCGCGGCGCTGGAGGCCAAGATTGC
ACAGCTGGAGGAGCAGGTCGAGCAGGAGGCCAGAGAGAAACAGGCGGCCACCAAGTCGCTGAAGCAGAAAGACAAGAAGCTGAAGGAAAT
CTTGCTGCAGGTGGAGGACGAGCGCAAGATGGCCGAGCAGTACAAGGAGCAGATCCAGGAAAGCGAGCACATGAAGGTGGAGAACAGCGA
GAATGGCAGCAAGCTCACCATCCTGGCCGCGCGCCAGGAGCACTGCGGCTGCTACACACTGCTGGTGGAGAACAAGCTGGGCAGCAGGCA
GGCCCAGGTCAACCTCACTGTCGTGGATAAGCCAGACCCCCCAGCTGGCACACCTTGTGCCTCTGACATTCGGAGCTCCTCACTGACCCT
GTCCTGGTATGGCTCCTCATATGATGGGGGCAGTGCTGTACAGTCCTACAGCATCGAGATCTGGGACTCAGCCAACAAGACGTGGAAGGA
ACTAGCCACATGCCGCAGCACCTCTTTCAACGTCCAGGACCTGCTGCCTGACCACGAATATAAGTTCCGTGTACGTGCAATCAACGTGTA
TGGAACCAGTGAGCCAAGCCAGGAGTCTGAACTCACAACGGTAGGAGAGAAACCTGAAGAGCCGAAGGATGAAGTGGAGGTGTCAGATGA
TGATGAGAAGGAGCCCGAGGTTGATTACCGGACAGTGACAATCAATACTGAACAAAAAGTATCTGACTTCTACGACATTGAGGAGAGATT
AGGATCTGGGAAATTTGGACAGGTCTTTCGACTTGTAGAAAAGAAAACTCGAAAAGTCTGGGCAGGGAAGTTCTTCAAGGCATATTCAGC
AAAAGAGAAAGAGAATATCCGGCAGGAGATTAGCATCATGAACTGCCTCCACCACCCTAAGCTGGTCCAGTGTGTGGATGCCTTTGAAGA
AAAGGCCAACATCGTCATGGTCCTGGAGATCGTGTCAGGAGGGGAGCTGTTTGAGCGCATCATTGACGAGGACTTTGAGCTGACGGAGCG
TGAGTGCATCAAGTACATGCGGCAGATCTCGGAGGGAGTGGAGTACATCCACAAGCAGGGCATCGTGCACCTGGACCTCAAGCCGGAGAA
CATCATGTGTGTCAACAAGACGGGCACCAGGATCAAGCTCATCGACTTTGGTCTGGCCAGGAGGCTGGAGAATGCGGGGTCTCTGAAGGT
CCTCTTTGGCACCCCAGAATTTGTGGCTCCTGAAGTGATCAACTATGAGCCCATCGGCTACGCCACAGACATGTGGAGCATCGGGGTCAT
CTGCTACATCCTAAACCGCCTGGACTGCACGCAGTGCCTTCAGCATCCATGGCTAATGAAAGATACCAAGAACATGGAGGCCAAGAAACT
CTCCAAGGACCGGATGAAGAAGTACATGGCAAGAAGGAAATGGCAGAAAACGGGCAATGCTGTGAGAGCCATTGGAAGACTGTCCTCTAT
GGCAATGATCTCAGGGCTCAGTGGCAGGAAATCCTCAACAGGGTCACCAACCAGCCCGCTCAATGCAGAAAAACTAGAATCTGAAGAAGA
TGTGTCCCAAGCTTTCCTTGAGGCTGTTGCTGAGGAAAAGCCTCATGTAAAACCCTATTTCTCTAAGACCATTCGCGATTTAGAAGTTGT
GGAGGGAAGTGCTGCTAGATTTGACTGCAAGATTGAAGGATACCCAGACCCCGAGGTTGTCTGGTTCAAAGATGACCAGTCAATCAGGGA
GTCCCGCCACTTCCAGATAGACTACGATGAGGACGGGAACTGCTCTTTAATTATTAGTGATGTTTGCGGGGATGACGATGCCAAGTACAC
CTGCAAGGCTGTCAACAGTCTTGGAGAAGCCACCTGCACAGCAGAGCTCATTGTGGAAACGATGGAGGAAGGTGAAGGGGAAGGGGAAGA
GGAAGAAGAGTGAAACAAAGCCAGAGAAAAGCAGTTTCTAAGTCATATTAAAAGGACTATTTCTCTAAAACTCAAAAAAAAAAAAAAAAC
TCAAGATAGTAAAAGCACCTAGTGTGATAGATTATCGGTTAGGTCATTTGTGGGTTGATTCTTCAGAAACAGCAGTTGATACCTAGCAGC
GTTATTGATGGGCATTAATCTATGTTAGTTGGCACCTTAAGATACTAGTGCAGCTAGATTTCATTTAGGGAAATCACCAGTAACTTGACT
GACCAATTGATTTTAGAGAGAAAGTAACCAAACCAAATATTTATCTGGGCAAAGTCATAAATTCTCCACTTGAATGCGCTCATGAAAAAT
AAGGCCAAAACAAGAGTTCTGGGCCACAGCTCAGCCCAGAGGGTTCCTGGGGATGGGAGGCCTCTCTCTCCCCACCCCCTGACTCTAGAG
AACTGGGTTTTCTCCCAGTACTCCAGCAATTCATTTCTGAAAGCAGTTGAGCCACTTTATTCCAAAGTACACTGCAGATGTTCAAACTCT
CCATTTCTCTTTCCCCTTCCACCTGCCAGTTTTGCTGACTCTCAACTTGTCATGAGTGTAAGCATTAAGGACATTATGCTTCTTCGATTC
TGAAGACAGGTCCCTGCTCATGGATGACTCTGGCTTCCTTAGGAAAATATTTTTCTTCCAAAATCAGTAGGAAATCTAAACTTATCCCCT
CTTTGCAGATGTCTAGCAGCTTCAGACATTTGGTTAAGAACCCATGGGAAAAAAAAAATCCTTGCTAATGTGGTTTCCTTTGTAAACCAG
GATTCTTATTTGTGCTGTTATAGAATATCAGCTCTGAACGTGTGGTAAAGATTTTTGTGTTTGAATATAGGAGAAATCAGTTTGCTGAAA
AGTTAGTCTTAATTATCTATTGGCCACGATGAAACAGATTTCAACTGATAAAGAGCTGGAGAACTCCATGTACTTTGGAATCTCCTCCAA
GATAGCCAGAGTTTAATACATCTTCATTCTCAACACTCTCCAAAGAACTTGACCTACCTTATGGGTTCCATATTTTTCTTCTTAAATGTG
CATCAATCATGCCTTGCCCCCAACCTTTAAATATATTCTTAGACCTGGTAAATGCACTCAGACTTGCGTCTTTAGGAATTTTTAACTTTC
TTTCACTACATTGGCACTTAAATTTTTTCTTTATAAAGCTTTTTGAAGGTCATAAACAAAGACCATAATTGATGATAGACCTAATACATT
TCCTCTGTGTGTGTGTGTAACATTCCAAATACTTTTTTTTTCTTTTCCACTGTTTGTAAGGTGCAACAATTTAATATTTTTAAGGGACTT
TTTAAGAGTTCCTTAAGAACCAATTTAAAATTACTTCAGTGCAATCCTACACAGTATCAACATTAGAATTTTGATATTAGTCTTATGTTA
TCTTCCATTCTATTTTTATCTGCTTTTTGCTGCTAGTTTCAAACTGCCAGTATTTTTCCTTTTGCTTTTAAAATAGTTACAATATTTTTC
ATGATAGCCACAGTATTGCCACAGTTTATTATAATAAAGGGTTTTTATTTGATTTAGCGCATTCAAAGCTTTTTTCTATCACTTTTGTGT
TCAGAATATAACCTTTGTGTGCGTGTATGTTGTGTGTGTGCATGTGTGGCGTATATGTGTGTTACAGGTTAATGCCTTCTTGGAATTGTG
TTAATGTTCTCTTGGTTTATTATGCCATCAGAATGGTAAATGAGAACACTACAACTGTAGTCAGCTCACAATTTTTAAATAAAGGATACC

>56300_56300_1_MYH11-MYLK_MYH11_chr16_15809021_ENST00000452625_MYLK_chr3_123383105_ENST00000359169_length(amino acids)=2473AA_BP=1887
MEIWDQQGTMAQKGQLSDDEKFLFVDKNFINSPVAQADWAAKRLVWVPSEKQGFEAASIKEEKGDEVVVELVENGKKVTVGKDDIQKMNP
PKFSKVEDMAELTCLNEASVLHNLRERYFSGLIYTYSGLFCVVVNPYKHLPIYSEKIVDMYKGKKRHEMPPHIYAIADTAYRSMLQDRED
QSILCTGESGAGKTENTKKVIQYLAVVASSHKGKKDTSITQGPSFAYGELEKQLLQANPILEAFGNAKTVKNDNSSRFGKFIRINFDVTG
YIVGANIETYLLEKSRAIRQARDERTFHIFYYMIAGAKEKMRSDLLLEGFNNYTFLSNGFVPIPAAQDDEMFQETVEAMAIMGFSEEEQL
SILKVVSSVLQLGNIVFKKERNTDQASMPDNTAAQKVCHLMGINVTDFTRSILTPRIKVGRDVVQKAQTKEQADFAVEALAKATYERLFR
WILTRVNKALDKTHRQGASFLGILDIAGFEIFEVNSFEQLCINYTNEKLQQLFNHTMFILEQEEYQREGIEWNFIDFGLDLQPCIELIER
PNNPPGVLALLDEECWFPKATDKSFVEKLCTEQGSHPKFQKPKQLKDKTEFSIIHYAGKVDYNASAWLTKNMDPLNDNVTSLLNASSDKF
VADLWKDVDRIVGLDQMAKMTESSLPSASKTKKGMFRTVGQLYKEQLGKLMTTLRNTTPNFVRCIIPNHEKRSGKLDAFLVLEQLRCNGV
LEGIRICRQGFPNRIVFQEFRQRYEILAANAIPKGFMDGKQACILMIKALELDPNLYRIGQSKIFFRTGVLAHLEEERDLKITDVIMAFQ
AMCRGYLARKAFAKRQQQLTAMKVIQRNCAAYLKLRNWQWWRLFTKVKPLLQVTRQEEEMQAKEDELQKTKERQQKAENELKELEQKHSQ
LTEEKNLLQEQLQAETELYAEAEEMRVRLAAKKQELEEILHEMEARLEEEEDRGQQLQAERKKMAQQMLDLEEQLEEEEAARQKLQLEKV
TAEAKIKKLEDEILVMDDQNNKLSKERKLLEERISDLTTNLAEEEEKAKNLTKLKNKHESMISELEVRLKKEEKSRQELEKLKRKLEGDA
SDFHEQIADLQAQIAELKMQLAKKEEELQAALARLDDEIAQKNNALKKIRELEGHISDLQEDLDSERAARNKAEKQKRDLGEELEALKTE
LEDTLDSTATQQELRAKREQEVTVLKKALDEETRSHEAQVQEMRQKHAQAVEELTEQLEQFKRAKANLDKNKQTLEKENADLAGELRVLG
QAKQEVEHKKKKLEAQVQELQSKCSDGERARAELNDKVHKLQNEVESVTGMLNEAEGKAIKLAKDVASLSSQLQDTQELLQEETRQKLNV
STKLRQLEEERNSLQDQLDEEMEAKQNLERHISTLNIQLSDSKKKLQDFASTVEALEEGKKRFQKEIENLTQQYEEKAAAYDKLEKTKNR
LQQELDDLVVDLDNQRQLVSNLEKKQRKFDQLLAEEKNISSKYADERDRAEAEAREKETKALSLARALEEALEAKEELERTNKMLKAEME
DLVSSKDDVGKNVHELEKSKRALETQMEEMKTQLEELEDELQATEDAKLRLEVNMQALKGQFERDLQARDEQNEEKRRQLQRQLHEYETE
LEDERKQRALAAAAKKKLEGDLKDLELQADSAIKGREEAIKQLRKLQAQMKDFQRELEDARASRDEIFATAKENEKKAKSLEADLMQLQE
DLAAAERARKQADLEKEELAEELASSLSGRNALQDEKRRLEARIAQLEEELEEEQGNMEAMSDRVRKATQQAEQLSNELATERSTAQKNE
SARQQLERQNKELRSKLHEMEGAVKSKFKSTIAALEAKIAQLEEQVEQEAREKQAATKSLKQKDKKLKEILLQVEDERKMAEQYKEQIQE
SEHMKVENSENGSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTVVDKPDPPAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSIEI
WDSANKTWKELATCRSTSFNVQDLLPDHEYKFRVRAINVYGTSEPSQESELTTVGEKPEEPKDEVEVSDDDEKEPEVDYRTVTINTEQKV
SDFYDIEERLGSGKFGQVFRLVEKKTRKVWAGKFFKAYSAKEKENIRQEISIMNCLHHPKLVQCVDAFEEKANIVMVLEIVSGGELFERI
IDEDFELTERECIKYMRQISEGVEYIHKQGIVHLDLKPENIMCVNKTGTRIKLIDFGLARRLENAGSLKVLFGTPEFVAPEVINYEPIGY
ATDMWSIGVICYILNRLDCTQCLQHPWLMKDTKNMEAKKLSKDRMKKYMARRKWQKTGNAVRAIGRLSSMAMISGLSGRKSSTGSPTSPL
NAEKLESEEDVSQAFLEAVAEEKPHVKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIISD

--------------------------------------------------------------
>56300_56300_2_MYH11-MYLK_MYH11_chr16_15809021_ENST00000452625_MYLK_chr3_123383105_ENST00000360304_length(transcript)=9443nt_BP=5722nt
GCCTGGGAGGTGCGTCAGATCCGAGCTCGCCATCCAGTTTCCTCTCCACTAGTCCCCCCAGTTGGAGATCTGGGACCAACAAGGCACCAT
GGCGCAGAAGGGCCAACTCAGTGACGATGAGAAGTTCCTCTTTGTGGACAAAAACTTCATCAACAGCCCAGTGGCCCAGGCTGACTGGGC
CGCCAAGAGACTCGTCTGGGTCCCCTCGGAGAAGCAGGGCTTCGAGGCAGCCAGCATTAAGGAGGAGAAGGGGGATGAGGTGGTTGTGGA
GCTGGTGGAGAATGGCAAGAAGGTCACGGTTGGGAAAGATGACATCCAGAAGATGAACCCACCCAAGTTCTCCAAGGTGGAGGACATGGC
GGAGCTGACGTGCCTCAACGAAGCCTCCGTGCTACACAACCTGAGGGAGCGGTACTTCTCAGGGCTAATATATACGTACTCTGGCCTCTT
CTGCGTGGTGGTCAACCCCTATAAACACCTGCCCATCTACTCGGAGAAGATCGTCGACATGTACAAGGGCAAGAAGAGGCACGAGATGCC
GCCTCACATCTACGCCATCGCAGACACGGCCTACCGGAGCATGCTTCAAGATCGGGAGGACCAGTCCATTCTATGCACAGGCGAGTCTGG
AGCCGGGAAAACCGAAAACACCAAGAAGGTCATTCAGTACCTGGCCGTGGTGGCCTCCTCCCACAAGGGCAAGAAAGACACAAGTATCAC
GCAAGGCCCATCTTTTGCCTACGGAGAGCTGGAAAAGCAGCTTCTACAAGCAAACCCGATTCTGGAGGCTTTCGGCAACGCCAAAACAGT
GAAGAACGACAACTCCTCACGATTCGGCAAATTCATCCGCATCAACTTCGACGTCACGGGTTACATCGTGGGAGCCAACATTGAGACCTA
TCTGCTAGAAAAATCACGGGCAATTCGCCAAGCCAGAGACGAGAGGACATTCCACATCTTTTACTACATGATTGCTGGAGCCAAGGAGAA
GATGAGAAGTGACTTGCTTTTGGAGGGCTTCAACAACTACACCTTCCTCTCCAATGGCTTTGTGCCCATCCCAGCAGCCCAGGATGATGA
GATGTTCCAGGAAACCGTGGAGGCCATGGCAATCATGGGTTTCAGCGAGGAGGAGCAGCTATCCATATTGAAGGTGGTATCATCGGTCCT
GCAGCTTGGAAATATCGTCTTCAAGAAGGAAAGAAACACAGACCAGGCGTCCATGCCAGATAACACAGCTGCTCAGAAAGTTTGCCACCT
CATGGGAATTAATGTGACAGATTTCACCAGATCCATCCTCACTCCTCGTATCAAGGTTGGGCGAGATGTGGTACAGAAAGCTCAGACAAA
AGAACAGGCTGACTTTGCTGTAGAGGCTTTGGCCAAGGCAACATATGAGCGCCTTTTCCGCTGGATACTCACCCGCGTGAACAAAGCCCT
GGACAAGACCCATCGGCAAGGGGCTTCCTTCCTGGGGATCCTGGATATAGCTGGATTTGAGATCTTTGAGGTGAACTCCTTCGAGCAGCT
GTGCATCAACTACACCAACGAGAAGCTGCAGCAGCTCTTCAACCACACCATGTTCATCCTGGAGCAGGAGGAGTACCAGCGCGAGGGCAT
CGAGTGGAACTTCATCGACTTTGGGCTGGACCTACAGCCCTGCATCGAGCTCATCGAGCGACCGAACAACCCTCCAGGTGTGCTGGCCCT
GCTGGACGAGGAATGCTGGTTCCCCAAAGCCACGGACAAGTCTTTCGTGGAGAAGCTGTGCACGGAGCAGGGCAGCCACCCCAAGTTCCA
GAAGCCCAAGCAGCTCAAGGACAAGACTGAGTTCTCCATCATCCATTATGCTGGGAAGGTGGACTATAATGCGAGTGCCTGGCTGACCAA
GAATATGGACCCGCTGAATGACAACGTGACTTCCCTGCTCAATGCCTCCTCCGACAAGTTTGTGGCCGACCTGTGGAAGGACGTGGACCG
CATCGTGGGCCTGGACCAGATGGCCAAGATGACGGAGAGCTCGCTGCCCAGCGCCTCCAAGACCAAGAAGGGCATGTTCCGCACAGTGGG
GCAGCTGTACAAGGAGCAGCTGGGCAAGCTGATGACCACGCTACGCAACACCACGCCCAACTTCGTGCGCTGCATCATCCCCAACCACGA
GAAGAGGTCCGGCAAGCTGGATGCGTTCCTGGTGCTGGAGCAGCTGCGGTGCAATGGGGTGCTGGAAGGCATTCGCATCTGCCGGCAGGG
CTTCCCCAACCGGATCGTCTTCCAGGAGTTCCGCCAACGCTACGAGATCCTGGCGGCGAATGCCATCCCCAAAGGCTTCATGGACGGGAA
GCAGGCCTGCATTCTCATGATCAAAGCCCTGGAACTTGACCCCAACTTATACAGGATAGGGCAGAGCAAAATCTTCTTCCGAACTGGCGT
CCTGGCCCACCTAGAGGAGGAGCGAGATTTGAAGATCACCGATGTCATCATGGCCTTCCAGGCGATGTGTCGTGGCTACTTGGCCAGAAA
GGCTTTTGCCAAGAGGCAGCAGCAGCTGACCGCCATGAAGGTGATTCAGAGGAACTGCGCCGCCTACCTCAAGCTGCGGAACTGGCAGTG
GTGGAGGCTTTTCACCAAAGTGAAGCCACTGCTGCAGGTGACACGGCAGGAGGAGGAGATGCAGGCCAAGGAGGATGAACTGCAGAAGAC
CAAGGAGCGGCAGCAGAAGGCAGAGAATGAGCTTAAGGAGCTGGAACAGAAGCACTCGCAGCTGACCGAGGAGAAGAACCTGCTACAGGA
ACAGCTGCAGGCAGAGACAGAGCTGTATGCAGAGGCTGAGGAGATGCGGGTGCGGCTGGCGGCCAAGAAGCAGGAGCTGGAGGAGATACT
GCATGAGATGGAGGCCCGCCTGGAGGAGGAGGAAGACAGGGGCCAGCAGCTACAGGCTGAAAGGAAGAAGATGGCCCAGCAGATGCTGGA
CCTTGAAGAACAGCTGGAGGAGGAGGAAGCTGCCAGGCAGAAGCTGCAACTTGAGAAGGTCACGGCTGAGGCCAAGATCAAGAAACTGGA
GGATGAGATCCTGGTCATGGATGATCAGAACAATAAACTATCAAAAGAACGAAAACTCCTTGAGGAGAGGATTAGTGACTTAACGACAAA
TCTTGCAGAAGAGGAAGAAAAGGCCAAGAATCTTACCAAGCTGAAAAACAAGCATGAATCTATGATTTCAGAACTGGAAGTGCGGCTAAA
GAAGGAAGAGAAGAGCCGACAGGAGCTGGAGAAGCTGAAACGGAAGCTGGAGGGTGATGCCAGCGACTTCCACGAGCAGATCGCTGACCT
CCAGGCGCAGATCGCAGAGCTCAAGATGCAGCTGGCCAAGAAGGAGGAGGAGCTGCAGGCGGCCCTGGCCAGGCTTGACGATGAAATCGC
TCAGAAGAACAATGCCCTGAAGAAGATCCGGGAGCTGGAGGGCCACATCTCAGACCTCCAGGAGGACCTGGACTCAGAGCGGGCCGCCAG
GAACAAGGCTGAAAAGCAGAAGCGAGACCTCGGCGAGGAGCTGGAGGCCCTAAAGACAGAGCTGGAAGACACACTGGACAGCACAGCCAC
TCAGCAGGAGCTCAGGGCCAAGAGGGAGCAGGAGGTGACGGTGCTGAAGAAGGCCCTGGATGAAGAGACGCGGTCCCATGAGGCTCAGGT
CCAGGAGATGAGGCAGAAACACGCACAGGCGGTGGAGGAGCTCACAGAGCAGCTTGAGCAGTTCAAGAGGGCCAAGGCGAACCTAGACAA
GAATAAGCAGACGCTGGAGAAAGAGAACGCAGACCTGGCCGGGGAGCTGCGGGTCCTGGGCCAGGCCAAGCAGGAGGTGGAACATAAGAA
GAAGAAGCTGGAGGCGCAGGTGCAGGAGCTGCAGTCCAAGTGCAGCGATGGGGAGCGGGCCCGGGCGGAGCTCAATGACAAAGTCCACAA
GCTGCAGAATGAAGTTGAGAGCGTCACAGGGATGCTTAACGAGGCCGAGGGGAAGGCCATTAAGCTGGCCAAGGACGTGGCGTCCCTCAG
TTCCCAGCTCCAGGACACCCAGGAGCTGCTTCAAGAAGAAACCCGGCAGAAGCTCAACGTGTCTACGAAGCTGCGCCAGCTGGAGGAGGA
GCGGAACAGCCTGCAAGACCAGCTGGACGAGGAGATGGAGGCCAAGCAGAACCTGGAGCGCCACATCTCCACTCTCAACATCCAGCTCTC
CGACTCGAAGAAGAAGCTGCAGGACTTTGCCAGCACCGTGGAAGCTCTGGAAGAGGGGAAGAAGAGGTTCCAGAAGGAGATCGAGAACCT
CACCCAGCAGTACGAGGAGAAGGCGGCCGCTTATGATAAACTGGAAAAGACCAAGAACAGGCTTCAGCAGGAGCTGGACGACCTGGTTGT
TGATTTGGACAACCAGCGGCAACTCGTGTCCAACCTGGAAAAGAAGCAGAGGAAATTTGATCAGTTGTTAGCCGAGGAGAAAAACATCTC
TTCCAAATACGCGGATGAGAGGGACAGAGCTGAGGCAGAAGCCAGGGAGAAGGAAACCAAGGCCCTGTCCCTGGCTCGGGCCCTTGAAGA
GGCCTTGGAAGCCAAAGAGGAACTCGAGCGGACCAACAAAATGCTCAAAGCCGAAATGGAAGACCTGGTCAGCTCCAAGGATGACGTGGG
CAAGAACGTCCATGAGCTGGAGAAGTCCAAGCGGGCCCTGGAGACCCAGATGGAGGAGATGAAGACGCAGCTGGAAGAGCTGGAGGACGA
GCTGCAAGCCACGGAGGACGCCAAACTGCGGCTGGAAGTCAACATGCAGGCGCTCAAGGGCCAGTTCGAAAGGGATCTCCAAGCCCGGGA
CGAGCAGAATGAGGAGAAGAGGAGGCAACTGCAGAGACAGCTTCACGAGTATGAGACGGAACTGGAAGACGAGCGAAAGCAACGTGCCCT
GGCAGCTGCAGCAAAGAAGAAGCTGGAAGGGGACCTGAAAGACCTGGAGCTTCAGGCCGACTCTGCCATCAAGGGGAGGGAGGAAGCCAT
CAAGCAGCTACGCAAACTGCAGGCTCAGATGAAGGACTTTCAAAGAGAGCTGGAAGATGCCCGTGCCTCCAGAGATGAGATCTTTGCCAC
AGCCAAAGAGAATGAGAAGAAAGCCAAGAGCTTGGAAGCAGACCTCATGCAGCTACAAGAGGACCTCGCCGCCGCTGAGAGGGCTCGCAA
ACAAGCGGACCTCGAGAAGGAGGAACTGGCAGAGGAGCTGGCCAGTAGCCTGTCGGGAAGGAACGCACTCCAGGACGAGAAGCGCCGCCT
GGAGGCCCGGATCGCCCAGCTGGAGGAGGAGCTGGAGGAGGAGCAGGGCAACATGGAGGCCATGAGCGACCGGGTCCGCAAAGCCACACA
GCAGGCCGAGCAGCTCAGCAACGAGCTGGCCACAGAGCGCAGCACGGCCCAGAAGAATGAGAGTGCCCGGCAGCAGCTCGAGCGGCAGAA
CAAGGAGCTCCGGAGCAAGCTCCACGAGATGGAGGGGGCCGTCAAGTCCAAGTTCAAGTCCACCATCGCGGCGCTGGAGGCCAAGATTGC
ACAGCTGGAGGAGCAGGTCGAGCAGGAGGCCAGAGAGAAACAGGCGGCCACCAAGTCGCTGAAGCAGAAAGACAAGAAGCTGAAGGAAAT
CTTGCTGCAGGTGGAGGACGAGCGCAAGATGGCCGAGCAGTACAAGGAGCAGATCCAGGAAAGCGAGCACATGAAGGTGGAGAACAGCGA
GAATGGCAGCAAGCTCACCATCCTGGCCGCGCGCCAGGAGCACTGCGGCTGCTACACACTGCTGGTGGAGAACAAGCTGGGCAGCAGGCA
GGCCCAGGTCAACCTCACTGTCGTGGATAAGCCAGACCCCCCAGCTGGCACACCTTGTGCCTCTGACATTCGGAGCTCCTCACTGACCCT
GTCCTGGTATGGCTCCTCATATGATGGGGGCAGTGCTGTACAGTCCTACAGCATCGAGATCTGGGACTCAGCCAACAAGACGTGGAAGGA
ACTAGCCACATGCCGCAGCACCTCTTTCAACGTCCAGGACCTGCTGCCTGACCACGAATATAAGTTCCGTGTACGTGCAATCAACGTGTA
TGGAACCAGTGAGCCAAGCCAGGAGTCTGAACTCACAACGGTAGGAGAGAAACCTGAAGAGCCGAAGGATGAAGTGGAGGTGTCAGATGA
TGATGAGAAGGAGCCCGAGGTTGATTACCGGACAGTGACAATCAATACTGAACAAAAAGTATCTGACTTCTACGACATTGAGGAGAGATT
AGGATCTGGGAAATTTGGACAGGTCTTTCGACTTGTAGAAAAGAAAACTCGAAAAGTCTGGGCAGGGAAGTTCTTCAAGGCATATTCAGC
AAAAGAGAAAGAGAATATCCGGCAGGAGATTAGCATCATGAACTGCCTCCACCACCCTAAGCTGGTCCAGTGTGTGGATGCCTTTGAAGA
AAAGGCCAACATCGTCATGGTCCTGGAGATCGTGTCAGGAGGGGAGCTGTTTGAGCGCATCATTGACGAGGACTTTGAGCTGACGGAGCG
TGAGTGCATCAAGTACATGCGGCAGATCTCGGAGGGAGTGGAGTACATCCACAAGCAGGGCATCGTGCACCTGGACCTCAAGCCGGAGAA
CATCATGTGTGTCAACAAGACGGGCACCAGGATCAAGCTCATCGACTTTGGTCTGGCCAGGAGGCTGGAGAATGCGGGGTCTCTGAAGGT
CCTCTTTGGCACCCCAGAATTTGTGGCTCCTGAAGTGATCAACTATGAGCCCATCGGCTACGCCACAGACATGTGGAGCATCGGGGTCAT
CTGCTACATCCTAGTCAGTGGCCTTTCCCCCTTCATGGGAGACAACGATAACGAAACCTTGGCCAACGTTACCTCAGCCACCTGGGACTT
CGACGACGAGGCATTCGATGAGATCTCCGACGATGCCAAGGATTTCATCAGCAATCTGCTGAAGAAAGATATGAAAAACCGCCTGGACTG
CACGCAGTGCCTTCAGCATCCATGGCTAATGAAAGATACCAAGAACATGGAGGCCAAGAAACTCTCCAAGGACCGGATGAAGAAGTACAT
GGCAAGAAGGAAATGGCAGAAAACGGGCAATGCTGTGAGAGCCATTGGAAGACTGTCCTCTATGGCAATGATCTCAGGGCTCAGTGGCAG
GAAATCCTCAACAGGGTCACCAACCAGCCCGCTCAATGCAGAAAAACTAGAATCTGAAGAAGATGTGTCCCAAGCTTTCCTTGAGGCTGT
TGCTGAGGAAAAGCCTCATGTAAAACCCTATTTCTCTAAGACCATTCGCGATTTAGAAGTTGTGGAGGGAAGTGCTGCTAGATTTGACTG
CAAGATTGAAGGATACCCAGACCCCGAGGTTGTCTGGTTCAAAGATGACCAGTCAATCAGGGAGTCCCGCCACTTCCAGATAGACTACGA
TGAGGACGGGAACTGCTCTTTAATTATTAGTGATGTTTGCGGGGATGACGATGCCAAGTACACCTGCAAGGCTGTCAACAGTCTTGGAGA
AGCCACCTGCACAGCAGAGCTCATTGTGGAAACGATGGAGGAAGGTGAAGGGGAAGGGGAAGAGGAAGAAGAGTGAAACAAAGCCAGAGA
AAAGCAGTTTCTAAGTCATATTAAAAGGACTATTTCTCTAAAACTCAAAAAAAAAAAAAAAACTCAAGATAGTAAAAGCACCTAGTGTGA
TAGATTATCGGTTAGGTCATTTGTGGGTTGATTCTTCAGAAACAGCAGTTGATACCTAGCAGCGTTATTGATGGGCATTAATCTATGTTA
GTTGGCACCTTAAGATACTAGTGCAGCTAGATTTCATTTAGGGAAATCACCAGTAACTTGACTGACCAATTGATTTTAGAGAGAAAGTAA
CCAAACCAAATATTTATCTGGGCAAAGTCATAAATTCTCCACTTGAATGCGCTCATGAAAAATAAGGCCAAAACAAGAGTTCTGGGCCAC
AGCTCAGCCCAGAGGGTTCCTGGGGATGGGAGGCCTCTCTCTCCCCACCCCCTGACTCTAGAGAACTGGGTTTTCTCCCAGTACTCCAGC
AATTCATTTCTGAAAGCAGTTGAGCCACTTTATTCCAAAGTACACTGCAGATGTTCAAACTCTCCATTTCTCTTTCCCCTTCCACCTGCC
AGTTTTGCTGACTCTCAACTTGTCATGAGTGTAAGCATTAAGGACATTATGCTTCTTCGATTCTGAAGACAGGTCCCTGCTCATGGATGA
CTCTGGCTTCCTTAGGAAAATATTTTTCTTCCAAAATCAGTAGGAAATCTAAACTTATCCCCTCTTTGCAGATGTCTAGCAGCTTCAGAC
ATTTGGTTAAGAACCCATGGGAAAAAAAAAATCCTTGCTAATGTGGTTTCCTTTGTAAACCAGGATTCTTATTTGTGCTGTTATAGAATA
TCAGCTCTGAACGTGTGGTAAAGATTTTTGTGTTTGAATATAGGAGAAATCAGTTTGCTGAAAAGTTAGTCTTAATTATCTATTGGCCAC
GATGAAACAGATTTCAACTGATAAAGAGCTGGAGAACTCCATGTACTTTGGAATCTCCTCCAAGATAGCCAGAGTTTAATACATCTTCAT
TCTCAACACTCTCCAAAGAACTTGACCTACCTTATGGGTTCCATATTTTTCTTCTTAAATGTGCATCAATCATGCCTTGCCCCCAACCTT
TAAATATATTCTTAGACCTGGTAAATGCACTCAGACTTGCGTCTTTAGGAATTTTTAACTTTCTTTCACTACATTGGCACTTAAATTTTT
TCTTTATAAAGCTTTTTGAAGGTCATAAACAAAGACCATAATTGATGATAGACCTAATACATTTCCTCTGTGTGTGTGTGTAACATTCCA
AATACTTTTTTTTTCTTTTCCACTGTTTGTAAGGTGCAACAATTTAATATTTTTAAGGGACTTTTTAAGAGTTCCTTAAGAACCAATTTA
AAATTACTTCAGTGCAATCCTACACAGTATCAACATTAGAATTTTGATATTAGTCTTATGTTATCTTCCATTCTATTTTTATCTGCTTTT
TGCTGCTAGTTTCAAACTGCCAGTATTTTTCCTTTTGCTTTTAAAATAGTTACAATATTTTTCATGATAGCCACAGTATTGCCACAGTTT
ATTATAATAAAGGGTTTTTATTTGATTTAGCGCATTCAAAGCTTTTTTCTATCACTTTTGTGTTCAGAATATAACCTTTGTGTGCGTGTA
TGTTGTGTGTGTGCATGTGTGGCGTATATGTGTGTTACAGGTTAATGCCTTCTTGGAATTGTGTTAATGTTCTCTTGGTTTATTATGCCA

>56300_56300_2_MYH11-MYLK_MYH11_chr16_15809021_ENST00000452625_MYLK_chr3_123383105_ENST00000360304_length(amino acids)=2524AA_BP=1887
MEIWDQQGTMAQKGQLSDDEKFLFVDKNFINSPVAQADWAAKRLVWVPSEKQGFEAASIKEEKGDEVVVELVENGKKVTVGKDDIQKMNP
PKFSKVEDMAELTCLNEASVLHNLRERYFSGLIYTYSGLFCVVVNPYKHLPIYSEKIVDMYKGKKRHEMPPHIYAIADTAYRSMLQDRED
QSILCTGESGAGKTENTKKVIQYLAVVASSHKGKKDTSITQGPSFAYGELEKQLLQANPILEAFGNAKTVKNDNSSRFGKFIRINFDVTG
YIVGANIETYLLEKSRAIRQARDERTFHIFYYMIAGAKEKMRSDLLLEGFNNYTFLSNGFVPIPAAQDDEMFQETVEAMAIMGFSEEEQL
SILKVVSSVLQLGNIVFKKERNTDQASMPDNTAAQKVCHLMGINVTDFTRSILTPRIKVGRDVVQKAQTKEQADFAVEALAKATYERLFR
WILTRVNKALDKTHRQGASFLGILDIAGFEIFEVNSFEQLCINYTNEKLQQLFNHTMFILEQEEYQREGIEWNFIDFGLDLQPCIELIER
PNNPPGVLALLDEECWFPKATDKSFVEKLCTEQGSHPKFQKPKQLKDKTEFSIIHYAGKVDYNASAWLTKNMDPLNDNVTSLLNASSDKF
VADLWKDVDRIVGLDQMAKMTESSLPSASKTKKGMFRTVGQLYKEQLGKLMTTLRNTTPNFVRCIIPNHEKRSGKLDAFLVLEQLRCNGV
LEGIRICRQGFPNRIVFQEFRQRYEILAANAIPKGFMDGKQACILMIKALELDPNLYRIGQSKIFFRTGVLAHLEEERDLKITDVIMAFQ
AMCRGYLARKAFAKRQQQLTAMKVIQRNCAAYLKLRNWQWWRLFTKVKPLLQVTRQEEEMQAKEDELQKTKERQQKAENELKELEQKHSQ
LTEEKNLLQEQLQAETELYAEAEEMRVRLAAKKQELEEILHEMEARLEEEEDRGQQLQAERKKMAQQMLDLEEQLEEEEAARQKLQLEKV
TAEAKIKKLEDEILVMDDQNNKLSKERKLLEERISDLTTNLAEEEEKAKNLTKLKNKHESMISELEVRLKKEEKSRQELEKLKRKLEGDA
SDFHEQIADLQAQIAELKMQLAKKEEELQAALARLDDEIAQKNNALKKIRELEGHISDLQEDLDSERAARNKAEKQKRDLGEELEALKTE
LEDTLDSTATQQELRAKREQEVTVLKKALDEETRSHEAQVQEMRQKHAQAVEELTEQLEQFKRAKANLDKNKQTLEKENADLAGELRVLG
QAKQEVEHKKKKLEAQVQELQSKCSDGERARAELNDKVHKLQNEVESVTGMLNEAEGKAIKLAKDVASLSSQLQDTQELLQEETRQKLNV
STKLRQLEEERNSLQDQLDEEMEAKQNLERHISTLNIQLSDSKKKLQDFASTVEALEEGKKRFQKEIENLTQQYEEKAAAYDKLEKTKNR
LQQELDDLVVDLDNQRQLVSNLEKKQRKFDQLLAEEKNISSKYADERDRAEAEAREKETKALSLARALEEALEAKEELERTNKMLKAEME
DLVSSKDDVGKNVHELEKSKRALETQMEEMKTQLEELEDELQATEDAKLRLEVNMQALKGQFERDLQARDEQNEEKRRQLQRQLHEYETE
LEDERKQRALAAAAKKKLEGDLKDLELQADSAIKGREEAIKQLRKLQAQMKDFQRELEDARASRDEIFATAKENEKKAKSLEADLMQLQE
DLAAAERARKQADLEKEELAEELASSLSGRNALQDEKRRLEARIAQLEEELEEEQGNMEAMSDRVRKATQQAEQLSNELATERSTAQKNE
SARQQLERQNKELRSKLHEMEGAVKSKFKSTIAALEAKIAQLEEQVEQEAREKQAATKSLKQKDKKLKEILLQVEDERKMAEQYKEQIQE
SEHMKVENSENGSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTVVDKPDPPAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSIEI
WDSANKTWKELATCRSTSFNVQDLLPDHEYKFRVRAINVYGTSEPSQESELTTVGEKPEEPKDEVEVSDDDEKEPEVDYRTVTINTEQKV
SDFYDIEERLGSGKFGQVFRLVEKKTRKVWAGKFFKAYSAKEKENIRQEISIMNCLHHPKLVQCVDAFEEKANIVMVLEIVSGGELFERI
IDEDFELTERECIKYMRQISEGVEYIHKQGIVHLDLKPENIMCVNKTGTRIKLIDFGLARRLENAGSLKVLFGTPEFVAPEVINYEPIGY
ATDMWSIGVICYILVSGLSPFMGDNDNETLANVTSATWDFDDEAFDEISDDAKDFISNLLKKDMKNRLDCTQCLQHPWLMKDTKNMEAKK
LSKDRMKKYMARRKWQKTGNAVRAIGRLSSMAMISGLSGRKSSTGSPTSPLNAEKLESEEDVSQAFLEAVAEEKPHVKPYFSKTIRDLEV
VEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDVCGDDDAKYTCKAVNSLGEATCTAELIVETMEEGEGEGE

--------------------------------------------------------------
>56300_56300_3_MYH11-MYLK_MYH11_chr16_15809021_ENST00000452625_MYLK_chr3_123383105_ENST00000360772_length(transcript)=11539nt_BP=5722nt
GCCTGGGAGGTGCGTCAGATCCGAGCTCGCCATCCAGTTTCCTCTCCACTAGTCCCCCCAGTTGGAGATCTGGGACCAACAAGGCACCAT
GGCGCAGAAGGGCCAACTCAGTGACGATGAGAAGTTCCTCTTTGTGGACAAAAACTTCATCAACAGCCCAGTGGCCCAGGCTGACTGGGC
CGCCAAGAGACTCGTCTGGGTCCCCTCGGAGAAGCAGGGCTTCGAGGCAGCCAGCATTAAGGAGGAGAAGGGGGATGAGGTGGTTGTGGA
GCTGGTGGAGAATGGCAAGAAGGTCACGGTTGGGAAAGATGACATCCAGAAGATGAACCCACCCAAGTTCTCCAAGGTGGAGGACATGGC
GGAGCTGACGTGCCTCAACGAAGCCTCCGTGCTACACAACCTGAGGGAGCGGTACTTCTCAGGGCTAATATATACGTACTCTGGCCTCTT
CTGCGTGGTGGTCAACCCCTATAAACACCTGCCCATCTACTCGGAGAAGATCGTCGACATGTACAAGGGCAAGAAGAGGCACGAGATGCC
GCCTCACATCTACGCCATCGCAGACACGGCCTACCGGAGCATGCTTCAAGATCGGGAGGACCAGTCCATTCTATGCACAGGCGAGTCTGG
AGCCGGGAAAACCGAAAACACCAAGAAGGTCATTCAGTACCTGGCCGTGGTGGCCTCCTCCCACAAGGGCAAGAAAGACACAAGTATCAC
GCAAGGCCCATCTTTTGCCTACGGAGAGCTGGAAAAGCAGCTTCTACAAGCAAACCCGATTCTGGAGGCTTTCGGCAACGCCAAAACAGT
GAAGAACGACAACTCCTCACGATTCGGCAAATTCATCCGCATCAACTTCGACGTCACGGGTTACATCGTGGGAGCCAACATTGAGACCTA
TCTGCTAGAAAAATCACGGGCAATTCGCCAAGCCAGAGACGAGAGGACATTCCACATCTTTTACTACATGATTGCTGGAGCCAAGGAGAA
GATGAGAAGTGACTTGCTTTTGGAGGGCTTCAACAACTACACCTTCCTCTCCAATGGCTTTGTGCCCATCCCAGCAGCCCAGGATGATGA
GATGTTCCAGGAAACCGTGGAGGCCATGGCAATCATGGGTTTCAGCGAGGAGGAGCAGCTATCCATATTGAAGGTGGTATCATCGGTCCT
GCAGCTTGGAAATATCGTCTTCAAGAAGGAAAGAAACACAGACCAGGCGTCCATGCCAGATAACACAGCTGCTCAGAAAGTTTGCCACCT
CATGGGAATTAATGTGACAGATTTCACCAGATCCATCCTCACTCCTCGTATCAAGGTTGGGCGAGATGTGGTACAGAAAGCTCAGACAAA
AGAACAGGCTGACTTTGCTGTAGAGGCTTTGGCCAAGGCAACATATGAGCGCCTTTTCCGCTGGATACTCACCCGCGTGAACAAAGCCCT
GGACAAGACCCATCGGCAAGGGGCTTCCTTCCTGGGGATCCTGGATATAGCTGGATTTGAGATCTTTGAGGTGAACTCCTTCGAGCAGCT
GTGCATCAACTACACCAACGAGAAGCTGCAGCAGCTCTTCAACCACACCATGTTCATCCTGGAGCAGGAGGAGTACCAGCGCGAGGGCAT
CGAGTGGAACTTCATCGACTTTGGGCTGGACCTACAGCCCTGCATCGAGCTCATCGAGCGACCGAACAACCCTCCAGGTGTGCTGGCCCT
GCTGGACGAGGAATGCTGGTTCCCCAAAGCCACGGACAAGTCTTTCGTGGAGAAGCTGTGCACGGAGCAGGGCAGCCACCCCAAGTTCCA
GAAGCCCAAGCAGCTCAAGGACAAGACTGAGTTCTCCATCATCCATTATGCTGGGAAGGTGGACTATAATGCGAGTGCCTGGCTGACCAA
GAATATGGACCCGCTGAATGACAACGTGACTTCCCTGCTCAATGCCTCCTCCGACAAGTTTGTGGCCGACCTGTGGAAGGACGTGGACCG
CATCGTGGGCCTGGACCAGATGGCCAAGATGACGGAGAGCTCGCTGCCCAGCGCCTCCAAGACCAAGAAGGGCATGTTCCGCACAGTGGG
GCAGCTGTACAAGGAGCAGCTGGGCAAGCTGATGACCACGCTACGCAACACCACGCCCAACTTCGTGCGCTGCATCATCCCCAACCACGA
GAAGAGGTCCGGCAAGCTGGATGCGTTCCTGGTGCTGGAGCAGCTGCGGTGCAATGGGGTGCTGGAAGGCATTCGCATCTGCCGGCAGGG
CTTCCCCAACCGGATCGTCTTCCAGGAGTTCCGCCAACGCTACGAGATCCTGGCGGCGAATGCCATCCCCAAAGGCTTCATGGACGGGAA
GCAGGCCTGCATTCTCATGATCAAAGCCCTGGAACTTGACCCCAACTTATACAGGATAGGGCAGAGCAAAATCTTCTTCCGAACTGGCGT
CCTGGCCCACCTAGAGGAGGAGCGAGATTTGAAGATCACCGATGTCATCATGGCCTTCCAGGCGATGTGTCGTGGCTACTTGGCCAGAAA
GGCTTTTGCCAAGAGGCAGCAGCAGCTGACCGCCATGAAGGTGATTCAGAGGAACTGCGCCGCCTACCTCAAGCTGCGGAACTGGCAGTG
GTGGAGGCTTTTCACCAAAGTGAAGCCACTGCTGCAGGTGACACGGCAGGAGGAGGAGATGCAGGCCAAGGAGGATGAACTGCAGAAGAC
CAAGGAGCGGCAGCAGAAGGCAGAGAATGAGCTTAAGGAGCTGGAACAGAAGCACTCGCAGCTGACCGAGGAGAAGAACCTGCTACAGGA
ACAGCTGCAGGCAGAGACAGAGCTGTATGCAGAGGCTGAGGAGATGCGGGTGCGGCTGGCGGCCAAGAAGCAGGAGCTGGAGGAGATACT
GCATGAGATGGAGGCCCGCCTGGAGGAGGAGGAAGACAGGGGCCAGCAGCTACAGGCTGAAAGGAAGAAGATGGCCCAGCAGATGCTGGA
CCTTGAAGAACAGCTGGAGGAGGAGGAAGCTGCCAGGCAGAAGCTGCAACTTGAGAAGGTCACGGCTGAGGCCAAGATCAAGAAACTGGA
GGATGAGATCCTGGTCATGGATGATCAGAACAATAAACTATCAAAAGAACGAAAACTCCTTGAGGAGAGGATTAGTGACTTAACGACAAA
TCTTGCAGAAGAGGAAGAAAAGGCCAAGAATCTTACCAAGCTGAAAAACAAGCATGAATCTATGATTTCAGAACTGGAAGTGCGGCTAAA
GAAGGAAGAGAAGAGCCGACAGGAGCTGGAGAAGCTGAAACGGAAGCTGGAGGGTGATGCCAGCGACTTCCACGAGCAGATCGCTGACCT
CCAGGCGCAGATCGCAGAGCTCAAGATGCAGCTGGCCAAGAAGGAGGAGGAGCTGCAGGCGGCCCTGGCCAGGCTTGACGATGAAATCGC
TCAGAAGAACAATGCCCTGAAGAAGATCCGGGAGCTGGAGGGCCACATCTCAGACCTCCAGGAGGACCTGGACTCAGAGCGGGCCGCCAG
GAACAAGGCTGAAAAGCAGAAGCGAGACCTCGGCGAGGAGCTGGAGGCCCTAAAGACAGAGCTGGAAGACACACTGGACAGCACAGCCAC
TCAGCAGGAGCTCAGGGCCAAGAGGGAGCAGGAGGTGACGGTGCTGAAGAAGGCCCTGGATGAAGAGACGCGGTCCCATGAGGCTCAGGT
CCAGGAGATGAGGCAGAAACACGCACAGGCGGTGGAGGAGCTCACAGAGCAGCTTGAGCAGTTCAAGAGGGCCAAGGCGAACCTAGACAA
GAATAAGCAGACGCTGGAGAAAGAGAACGCAGACCTGGCCGGGGAGCTGCGGGTCCTGGGCCAGGCCAAGCAGGAGGTGGAACATAAGAA
GAAGAAGCTGGAGGCGCAGGTGCAGGAGCTGCAGTCCAAGTGCAGCGATGGGGAGCGGGCCCGGGCGGAGCTCAATGACAAAGTCCACAA
GCTGCAGAATGAAGTTGAGAGCGTCACAGGGATGCTTAACGAGGCCGAGGGGAAGGCCATTAAGCTGGCCAAGGACGTGGCGTCCCTCAG
TTCCCAGCTCCAGGACACCCAGGAGCTGCTTCAAGAAGAAACCCGGCAGAAGCTCAACGTGTCTACGAAGCTGCGCCAGCTGGAGGAGGA
GCGGAACAGCCTGCAAGACCAGCTGGACGAGGAGATGGAGGCCAAGCAGAACCTGGAGCGCCACATCTCCACTCTCAACATCCAGCTCTC
CGACTCGAAGAAGAAGCTGCAGGACTTTGCCAGCACCGTGGAAGCTCTGGAAGAGGGGAAGAAGAGGTTCCAGAAGGAGATCGAGAACCT
CACCCAGCAGTACGAGGAGAAGGCGGCCGCTTATGATAAACTGGAAAAGACCAAGAACAGGCTTCAGCAGGAGCTGGACGACCTGGTTGT
TGATTTGGACAACCAGCGGCAACTCGTGTCCAACCTGGAAAAGAAGCAGAGGAAATTTGATCAGTTGTTAGCCGAGGAGAAAAACATCTC
TTCCAAATACGCGGATGAGAGGGACAGAGCTGAGGCAGAAGCCAGGGAGAAGGAAACCAAGGCCCTGTCCCTGGCTCGGGCCCTTGAAGA
GGCCTTGGAAGCCAAAGAGGAACTCGAGCGGACCAACAAAATGCTCAAAGCCGAAATGGAAGACCTGGTCAGCTCCAAGGATGACGTGGG
CAAGAACGTCCATGAGCTGGAGAAGTCCAAGCGGGCCCTGGAGACCCAGATGGAGGAGATGAAGACGCAGCTGGAAGAGCTGGAGGACGA
GCTGCAAGCCACGGAGGACGCCAAACTGCGGCTGGAAGTCAACATGCAGGCGCTCAAGGGCCAGTTCGAAAGGGATCTCCAAGCCCGGGA
CGAGCAGAATGAGGAGAAGAGGAGGCAACTGCAGAGACAGCTTCACGAGTATGAGACGGAACTGGAAGACGAGCGAAAGCAACGTGCCCT
GGCAGCTGCAGCAAAGAAGAAGCTGGAAGGGGACCTGAAAGACCTGGAGCTTCAGGCCGACTCTGCCATCAAGGGGAGGGAGGAAGCCAT
CAAGCAGCTACGCAAACTGCAGGCTCAGATGAAGGACTTTCAAAGAGAGCTGGAAGATGCCCGTGCCTCCAGAGATGAGATCTTTGCCAC
AGCCAAAGAGAATGAGAAGAAAGCCAAGAGCTTGGAAGCAGACCTCATGCAGCTACAAGAGGACCTCGCCGCCGCTGAGAGGGCTCGCAA
ACAAGCGGACCTCGAGAAGGAGGAACTGGCAGAGGAGCTGGCCAGTAGCCTGTCGGGAAGGAACGCACTCCAGGACGAGAAGCGCCGCCT
GGAGGCCCGGATCGCCCAGCTGGAGGAGGAGCTGGAGGAGGAGCAGGGCAACATGGAGGCCATGAGCGACCGGGTCCGCAAAGCCACACA
GCAGGCCGAGCAGCTCAGCAACGAGCTGGCCACAGAGCGCAGCACGGCCCAGAAGAATGAGAGTGCCCGGCAGCAGCTCGAGCGGCAGAA
CAAGGAGCTCCGGAGCAAGCTCCACGAGATGGAGGGGGCCGTCAAGTCCAAGTTCAAGTCCACCATCGCGGCGCTGGAGGCCAAGATTGC
ACAGCTGGAGGAGCAGGTCGAGCAGGAGGCCAGAGAGAAACAGGCGGCCACCAAGTCGCTGAAGCAGAAAGACAAGAAGCTGAAGGAAAT
CTTGCTGCAGGTGGAGGACGAGCGCAAGATGGCCGAGCAGTACAAGGAGCAGATCCAGGAAAGCGAGCACATGAAGGTGGAGAACAGCGA
GAATGGCAGCAAGCTCACCATCCTGGCCGCGCGCCAGGAGCACTGCGGCTGCTACACACTGCTGGTGGAGAACAAGCTGGGCAGCAGGCA
GGCCCAGGTCAACCTCACTGTCGTGGATAAGCCAGACCCCCCAGCTGGCACACCTTGTGCCTCTGACATTCGGAGCTCCTCACTGACCCT
GTCCTGGTATGGCTCCTCATATGATGGGGGCAGTGCTGTACAGTCCTACAGCATCGAGATCTGGGACTCAGCCAACAAGACGTGGAAGGA
ACTAGCCACATGCCGCAGCACCTCTTTCAACGTCCAGGACCTGCTGCCTGACCACGAATATAAGTTCCGTGTACGTGCAATCAACGTGTA
TGGAACCAGTGAGCCAAGCCAGGAGTCTGAACTCACAACGGTAGGAGAGAAACCTGAAGAGCCGAAGGATGAAGTGGAGGTGTCAGATGA
TGATGAGAAGGAGCCCGAGGTTGATTACCGGACAGTGACAATCAATACTGAACAAAAAGTATCTGACTTCTACGACATTGAGGAGAGATT
AGGATCTGGGAAATTTGGACAGGTCTTTCGACTTGTAGAAAAGAAAACTCGAAAAGTCTGGGCAGGGAAGTTCTTCAAGGCATATTCAGC
AAAAGAGAAAGAGAATATCCGGCAGGAGATTAGCATCATGAACTGCCTCCACCACCCTAAGCTGGTCCAGTGTGTGGATGCCTTTGAAGA
AAAGGCCAACATCGTCATGGTCCTGGAGATCGTGTCAGGAGGGGAGCTGTTTGAGCGCATCATTGACGAGGACTTTGAGCTGACGGAGCG
TGAGTGCATCAAGTACATGCGGCAGATCTCGGAGGGAGTGGAGTACATCCACAAGCAGGGCATCGTGCACCTGGACCTCAAGCCGGAGAA
CATCATGTGTGTCAACAAGACGGGCACCAGGATCAAGCTCATCGACTTTGGTCTGGCCAGGAGGCTGGAGAATGCGGGGTCTCTGAAGGT
CCTCTTTGGCACCCCAGAATTTGTGGCTCCTGAAGTGATCAACTATGAGCCCATCGGCTACGCCACAGACATGTGGAGCATCGGGGTCAT
CTGCTACATCCTAAACCGCCTGGACTGCACGCAGTGCCTTCAGCATCCATGGCTAATGAAAGATACCAAGAACATGGAGGCCAAGAAACT
CTCCAAGGACCGGATGAAGAAGTACATGGCAAGAAGGAAATGGCAGAAAACGGGCAATGCTGTGAGAGCCATTGGAAGACTGTCCTCTAT
GGCAATGATCTCAGGGCTCAGTGGCAGGAAATCCTCAACAGGGTCACCAACCAGCCCGCTCAATGCAGAAAAACTAGAATCTGAAGAAGA
TGTGTCCCAAGCTTTCCTTGAGGCTGTTGCTGAGGAAAAGCCTCATGTAAAACCCTATTTCTCTAAGACCATTCGCGATTTAGAAGTTGT
GGAGGGAAGTGCTGCTAGATTTGACTGCAAGATTGAAGGATACCCAGACCCCGAGGTTGTCTGGTTCAAAGATGACCAGTCAATCAGGGA
GTCCCGCCACTTCCAGATAGACTACGATGAGGACGGGAACTGCTCTTTAATTATTAGTGATGTTTGCGGGGATGACGATGCCAAGTACAC
CTGCAAGGCTGTCAACAGTCTTGGAGAAGCCACCTGCACAGCAGAGCTCATTGTGGAAACGATGGAGGAAGGTGAAGGGGAAGGGGAAGA
GGAAGAAGAGTGAAACAAAGCCAGAGAAAAGCAGTTTCTAAGTCATATTAAAAGGACTATTTCTCTAAAACTCAAAAAAAAAAAAAAAAC
TCAAGATAGTAAAAGCACCTAGTGTGATAGATTATCGGTTAGGTCATTTGTGGGTTGATTCTTCAGAAACAGCAGTTGATACCTAGCAGC
GTTATTGATGGGCATTAATCTATGTTAGTTGGCACCTTAAGATACTAGTGCAGCTAGATTTCATTTAGGGAAATCACCAGTAACTTGACT
GACCAATTGATTTTAGAGAGAAAGTAACCAAACCAAATATTTATCTGGGCAAAGTCATAAATTCTCCACTTGAATGCGCTCATGAAAAAT
AAGGCCAAAACAAGAGTTCTGGGCCACAGCTCAGCCCAGAGGGTTCCTGGGGATGGGAGGCCTCTCTCTCCCCACCCCCTGACTCTAGAG
AACTGGGTTTTCTCCCAGTACTCCAGCAATTCATTTCTGAAAGCAGTTGAGCCACTTTATTCCAAAGTACACTGCAGATGTTCAAACTCT
CCATTTCTCTTTCCCCTTCCACCTGCCAGTTTTGCTGACTCTCAACTTGTCATGAGTGTAAGCATTAAGGACATTATGCTTCTTCGATTC
TGAAGACAGGTCCCTGCTCATGGATGACTCTGGCTTCCTTAGGAAAATATTTTTCTTCCAAAATCAGTAGGAAATCTAAACTTATCCCCT
CTTTGCAGATGTCTAGCAGCTTCAGACATTTGGTTAAGAACCCATGGGAAAAAAAAAATCCTTGCTAATGTGGTTTCCTTTGTAAACCAG
GATTCTTATTTGTGCTGTTATAGAATATCAGCTCTGAACGTGTGGTAAAGATTTTTGTGTTTGAATATAGGAGAAATCAGTTTGCTGAAA
AGTTAGTCTTAATTATCTATTGGCCACGATGAAACAGATTTCAACTGATAAAGAGCTGGAGAACTCCATGTACTTTGGAATCTCCTCCAA
GATAGCCAGAGTTTAATACATCTTCATTCTCAACACTCTCCAAAGAACTTGACCTACCTTATGGGTTCCATATTTTTCTTCTTAAATGTG
CATCAATCATGCCTTGCCCCCAACCTTTAAATATATTCTTAGACCTGGTAAATGCACTCAGACTTGCGTCTTTAGGAATTTTTAACTTTC
TTTCACTACATTGGCACTTAAATTTTTTCTTTATAAAGCTTTTTGAAGGTCATAAACAAAGACCATAATTGATGATAGACCTAATACATT
TCCTCTGTGTGTGTGTGTAACATTCCAAATACTTTTTTTTTCTTTTCCACTGTTTGTAAGGTGCAACAATTTAATATTTTTAAGGGACTT
TTTAAGAGTTCCTTAAGAACCAATTTAAAATTACTTCAGTGCAATCCTACACAGTATCAACATTAGAATTTTGATATTAGTCTTATGTTA
TCTTCCATTCTATTTTTATCTGCTTTTTGCTGCTAGTTTCAAACTGCCAGTATTTTTCCTTTTGCTTTTAAAATAGTTACAATATTTTTC
ATGATAGCCACAGTATTGCCACAGTTTATTATAATAAAGGGTTTTTATTTGATTTAGCGCATTCAAAGCTTTTTTCTATCACTTTTGTGT
TCAGAATATAACCTTTGTGTGCGTGTATGTTGTGTGTGTGCATGTGTGGCGTATATGTGTGTTACAGGTTAATGCCTTCTTGGAATTGTG
TTAATGTTCTCTTGGTTTATTATGCCATCAGAATGGTAAATGAGAACACTACAACTGTAGTCAGCTCACAATTTTTAAATAAAGGATACC
ACAGTGCATGCTGTTTGTTCAATCTTTGCAGACTTCTCTTTCTTTCCATGCTACCAGTTGTAAAGGACACAGCTATATCCTGGAAATGAA
AAACAAACACTGTGGTGCCTAGATGTGAAGAACTGGCTTATGTGGTTGTGTTTTGCTATGGAACAGAATGATTTAGGAAGTTCTTGTTTA
TATAGGTAGCCGAATTTACACATTTAGTTCAAAATTTCTCTTGAGCATCAGCTTAGTACTATATCAATCATTCTAGAAGGATATCTTATA
GAGCAGGTGTCCCCAACCCCCGGTAAGTAGCCTGTTAGGAACCAGGTCACACATAAGGAGGTTAGCAGTGGGCAAGTGAGCAAAGCATCA
TCTATATTTACAGCCGATCCCCATTGCTCGCATTACCGCCTGAGCTCTGCCTCCTGTCAGATCAGCGGCAGCATCAGGTTCTCTCAGGAA
CGAACTCTATTGTGAACTGCTCATGTGAGGGATCTAGGTTTCACGCTCCTTATGAGAATCTAACACCTGATGATCTGTCACTGTCTCCCA
TCACCCCTAGATGGGACAGTCTAGTTGCAGGAAAACAAGCTCAGGGCTTCCACTGATTCTACATTATGATGAGTTGTATACTTATTTTAT
ATTATAATAAAATATATTATTACAATGTAATAATAATAGAAATAAAATGCACAATACATGTAATGTGCTTGAATAATCCCAAAACCACCC
CCTCTCCTGGTCCATGGAAAAACTGTCTTCCATGAAAGTGGTCCCTGGTGCCAAAAAGGTTAGGGACCACTGTTACAGAGTATCAGGTCC
TCAAGATGCTAAAATCTATATGACATTTTTAACATGTGACATTATCATCATCATCATCATCATCATCACTGATGATACTATTTACCAGGG
CATGGTTTGAATTGGTGACTTTGGTGCAGTTCATTATTGGCAGCCAAATGCTTTATCCATACCTTCATATTGAAGAATTTGTTATCAGGA
AACTACCAGTCCTGCTTTACAGGAAGTCTGTTATCAGATATCAGATGGCAAGTTCCCCATGTCTTCAGATGTTCAAACAATATTGTGGAT
GGTCTAGAAAGAGTTTAAGACATGCTGTTAAATGTAGGGCTAGATAATTCTCTGATTCTTTGATGTAGTCTGGAAAGAAACAATCCATTG
TCCAGTTAATAAATATTTAGTGTTTTCATTTTTAAGACACTCACAATCCACAAATGTCCCTAACAATTTATTATTTTTAAAGAAAATGAC
TTTTTATTCCTTGCTAGTGAAAAATGTACAATTTATATGCTGCACTGAGAAAAATAACAGATATACTTTCTTCCATTCATTTTCATCCCA
AACATATAAAAAATAATCCATTGATTGTTCCTTGCATTGCATATCTTATTAAAAGATATTTCCTACATGCAACTAATAAGACATGCTGAC
TGTTGTCAGCTCTAAATTTATGTAAAGATTTTTTATTTTTGTTAAAATGTTTGAAATTTGCTTTTTGCTCCACACCTCACCTGTTTTTGA
TAAATCTGTGCTAATAAGTACATAGGAGGTAATAAATAATTGAGTTGTGAGAAACCCAATTCTCCATTTTTCAAGAAAACACAAGTAGCA
CTACTCTCTTTATCCCTTGGGACTCCTTCCTGTAATTTGAAAGGGGGGGCTAATGTTGGTGGCAGTTGTTGCTAAGGATCTCTGCACAGA
GTTAGGGCTTCACTCTCGGCTTCCTGGTTAGATGGGGCCATGTGACTAGTCCTAGTCAGTGAGCTGTGACCAGAAGTGATGTATGTACCC
TCGGGACCAGAGCATTTATGTGCTGGTACAAGCCTCTCCATAATGACGGGCAACACATGAGATGGTGGCTGCTGCAGCCATCTGGGTCTC
TAGCCAACCCAAAATGGGGACATAACACAAGCAAGAAATAAACATTTGTTCTTATAAATCACCAAGATTTTGGGGTTCTCAGTGGCTGCA
ACATAACCTAGACTATCCTGATACAGGCTTATCACCATGTTCTGGATGTGTGGTGACCAGGATGGTAGCCACTACTCACAAGTGGCTATT
TAAATTTAAGTTACTTTAAAAAATAAAATAAAAAATTCAGTTCCTCAGTTGTATGAGTTACATTTCAAATGCTCGACAGTCACATGTACA
TCACTTTTCAAATTATGTGAAATTAAAACTGAAAAGCTTGTGTGAAAGTCTAGAGAGTATGGTCTATAGTTTCATCAATTGTATTGGATA

>56300_56300_3_MYH11-MYLK_MYH11_chr16_15809021_ENST00000452625_MYLK_chr3_123383105_ENST00000360772_length(amino acids)=2473AA_BP=1887
MEIWDQQGTMAQKGQLSDDEKFLFVDKNFINSPVAQADWAAKRLVWVPSEKQGFEAASIKEEKGDEVVVELVENGKKVTVGKDDIQKMNP
PKFSKVEDMAELTCLNEASVLHNLRERYFSGLIYTYSGLFCVVVNPYKHLPIYSEKIVDMYKGKKRHEMPPHIYAIADTAYRSMLQDRED
QSILCTGESGAGKTENTKKVIQYLAVVASSHKGKKDTSITQGPSFAYGELEKQLLQANPILEAFGNAKTVKNDNSSRFGKFIRINFDVTG
YIVGANIETYLLEKSRAIRQARDERTFHIFYYMIAGAKEKMRSDLLLEGFNNYTFLSNGFVPIPAAQDDEMFQETVEAMAIMGFSEEEQL
SILKVVSSVLQLGNIVFKKERNTDQASMPDNTAAQKVCHLMGINVTDFTRSILTPRIKVGRDVVQKAQTKEQADFAVEALAKATYERLFR
WILTRVNKALDKTHRQGASFLGILDIAGFEIFEVNSFEQLCINYTNEKLQQLFNHTMFILEQEEYQREGIEWNFIDFGLDLQPCIELIER
PNNPPGVLALLDEECWFPKATDKSFVEKLCTEQGSHPKFQKPKQLKDKTEFSIIHYAGKVDYNASAWLTKNMDPLNDNVTSLLNASSDKF
VADLWKDVDRIVGLDQMAKMTESSLPSASKTKKGMFRTVGQLYKEQLGKLMTTLRNTTPNFVRCIIPNHEKRSGKLDAFLVLEQLRCNGV
LEGIRICRQGFPNRIVFQEFRQRYEILAANAIPKGFMDGKQACILMIKALELDPNLYRIGQSKIFFRTGVLAHLEEERDLKITDVIMAFQ
AMCRGYLARKAFAKRQQQLTAMKVIQRNCAAYLKLRNWQWWRLFTKVKPLLQVTRQEEEMQAKEDELQKTKERQQKAENELKELEQKHSQ
LTEEKNLLQEQLQAETELYAEAEEMRVRLAAKKQELEEILHEMEARLEEEEDRGQQLQAERKKMAQQMLDLEEQLEEEEAARQKLQLEKV
TAEAKIKKLEDEILVMDDQNNKLSKERKLLEERISDLTTNLAEEEEKAKNLTKLKNKHESMISELEVRLKKEEKSRQELEKLKRKLEGDA
SDFHEQIADLQAQIAELKMQLAKKEEELQAALARLDDEIAQKNNALKKIRELEGHISDLQEDLDSERAARNKAEKQKRDLGEELEALKTE
LEDTLDSTATQQELRAKREQEVTVLKKALDEETRSHEAQVQEMRQKHAQAVEELTEQLEQFKRAKANLDKNKQTLEKENADLAGELRVLG
QAKQEVEHKKKKLEAQVQELQSKCSDGERARAELNDKVHKLQNEVESVTGMLNEAEGKAIKLAKDVASLSSQLQDTQELLQEETRQKLNV
STKLRQLEEERNSLQDQLDEEMEAKQNLERHISTLNIQLSDSKKKLQDFASTVEALEEGKKRFQKEIENLTQQYEEKAAAYDKLEKTKNR
LQQELDDLVVDLDNQRQLVSNLEKKQRKFDQLLAEEKNISSKYADERDRAEAEAREKETKALSLARALEEALEAKEELERTNKMLKAEME
DLVSSKDDVGKNVHELEKSKRALETQMEEMKTQLEELEDELQATEDAKLRLEVNMQALKGQFERDLQARDEQNEEKRRQLQRQLHEYETE
LEDERKQRALAAAAKKKLEGDLKDLELQADSAIKGREEAIKQLRKLQAQMKDFQRELEDARASRDEIFATAKENEKKAKSLEADLMQLQE
DLAAAERARKQADLEKEELAEELASSLSGRNALQDEKRRLEARIAQLEEELEEEQGNMEAMSDRVRKATQQAEQLSNELATERSTAQKNE
SARQQLERQNKELRSKLHEMEGAVKSKFKSTIAALEAKIAQLEEQVEQEAREKQAATKSLKQKDKKLKEILLQVEDERKMAEQYKEQIQE
SEHMKVENSENGSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTVVDKPDPPAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSIEI
WDSANKTWKELATCRSTSFNVQDLLPDHEYKFRVRAINVYGTSEPSQESELTTVGEKPEEPKDEVEVSDDDEKEPEVDYRTVTINTEQKV
SDFYDIEERLGSGKFGQVFRLVEKKTRKVWAGKFFKAYSAKEKENIRQEISIMNCLHHPKLVQCVDAFEEKANIVMVLEIVSGGELFERI
IDEDFELTERECIKYMRQISEGVEYIHKQGIVHLDLKPENIMCVNKTGTRIKLIDFGLARRLENAGSLKVLFGTPEFVAPEVINYEPIGY
ATDMWSIGVICYILNRLDCTQCLQHPWLMKDTKNMEAKKLSKDRMKKYMARRKWQKTGNAVRAIGRLSSMAMISGLSGRKSSTGSPTSPL
NAEKLESEEDVSQAFLEAVAEEKPHVKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIISD

--------------------------------------------------------------
>56300_56300_4_MYH11-MYLK_MYH11_chr16_15809021_ENST00000576790_MYLK_chr3_123383105_ENST00000359169_length(transcript)=9291nt_BP=5723nt
GCAGGGAGATTTGGACGCTCCGGCCTGGGAGGTGCGTCAGATCCGAGCTCGCCATCCAGTTTCCTCTCCACTAGTCCCCCCAGTTGGAGA
TCTGGGACCAACAAGGCACCATGGCGCAGAAGGGCCAACTCAGTGACGATGAGAAGTTCCTCTTTGTGGACAAAAACTTCATCAACAGCC
CAGTGGCCCAGGCTGACTGGGCCGCCAAGAGACTCGTCTGGGTCCCCTCGGAGAAGCAGGGCTTCGAGGCAGCCAGCATTAAGGAGGAGA
AGGGGGATGAGGTGGTTGTGGAGCTGGTGGAGAATGGCAAGAAGGTCACGGTTGGGAAAGATGACATCCAGAAGATGAACCCACCCAAGT
TCTCCAAGGTGGAGGACATGGCGGAGCTGACGTGCCTCAACGAAGCCTCCGTGCTACACAACCTGAGGGAGCGGTACTTCTCAGGGCTAA
TATATACGTACTCTGGCCTCTTCTGCGTGGTGGTCAACCCCTATAAACACCTGCCCATCTACTCGGAGAAGATCGTCGACATGTACAAGG
GCAAGAAGAGGCACGAGATGCCGCCTCACATCTACGCCATCGCAGACACGGCCTACCGGAGCATGCTTCAAGATCGGGAGGACCAGTCCA
TTCTATGCACAGGCGAGTCTGGAGCCGGGAAAACCGAAAACACCAAGAAGGTCATTCAGTACCTGGCCGTGGTGGCCTCCTCCCACAAGG
GCAAGAAAGACACAAGTATCACGGGAGAGCTGGAAAAGCAGCTTCTACAAGCAAACCCGATTCTGGAGGCTTTCGGCAACGCCAAAACAG
TGAAGAACGACAACTCCTCACGATTCGGCAAATTCATCCGCATCAACTTCGACGTCACGGGTTACATCGTGGGAGCCAACATTGAGACCT
ATCTGCTAGAAAAATCACGGGCAATTCGCCAAGCCAGAGACGAGAGGACATTCCACATCTTTTACTACATGATTGCTGGAGCCAAGGAGA
AGATGAGAAGTGACTTGCTTTTGGAGGGCTTCAACAACTACACCTTCCTCTCCAATGGCTTTGTGCCCATCCCAGCAGCCCAGGATGATG
AGATGTTCCAGGAAACCGTGGAGGCCATGGCAATCATGGGTTTCAGCGAGGAGGAGCAGCTATCCATATTGAAGGTGGTATCATCGGTCC
TGCAGCTTGGAAATATCGTCTTCAAGAAGGAAAGAAACACAGACCAGGCGTCCATGCCAGATAACACAGCTGCTCAGAAAGTTTGCCACC
TCATGGGAATTAATGTGACAGATTTCACCAGATCCATCCTCACTCCTCGTATCAAGGTTGGGCGAGATGTGGTACAGAAAGCTCAGACAA
AAGAACAGGCTGACTTTGCTGTAGAGGCTTTGGCCAAGGCAACATATGAGCGCCTTTTCCGCTGGATACTCACCCGCGTGAACAAAGCCC
TGGACAAGACCCATCGGCAAGGGGCTTCCTTCCTGGGGATCCTGGATATAGCTGGATTTGAGATCTTTGAGGTGAACTCCTTCGAGCAGC
TGTGCATCAACTACACCAACGAGAAGCTGCAGCAGCTCTTCAACCACACCATGTTCATCCTGGAGCAGGAGGAGTACCAGCGCGAGGGCA
TCGAGTGGAACTTCATCGACTTTGGGCTGGACCTACAGCCCTGCATCGAGCTCATCGAGCGACCGAACAACCCTCCAGGTGTGCTGGCCC
TGCTGGACGAGGAATGCTGGTTCCCCAAAGCCACGGACAAGTCTTTCGTGGAGAAGCTGTGCACGGAGCAGGGCAGCCACCCCAAGTTCC
AGAAGCCCAAGCAGCTCAAGGACAAGACTGAGTTCTCCATCATCCATTATGCTGGGAAGGTGGACTATAATGCGAGTGCCTGGCTGACCA
AGAATATGGACCCGCTGAATGACAACGTGACTTCCCTGCTCAATGCCTCCTCCGACAAGTTTGTGGCCGACCTGTGGAAGGACGTGGACC
GCATCGTGGGCCTGGACCAGATGGCCAAGATGACGGAGAGCTCGCTGCCCAGCGCCTCCAAGACCAAGAAGGGCATGTTCCGCACAGTGG
GGCAGCTGTACAAGGAGCAGCTGGGCAAGCTGATGACCACGCTACGCAACACCACGCCCAACTTCGTGCGCTGCATCATCCCCAACCACG
AGAAGAGGTCCGGCAAGCTGGATGCGTTCCTGGTGCTGGAGCAGCTGCGGTGCAATGGGGTGCTGGAAGGCATTCGCATCTGCCGGCAGG
GCTTCCCCAACCGGATCGTCTTCCAGGAGTTCCGCCAACGCTACGAGATCCTGGCGGCGAATGCCATCCCCAAAGGCTTCATGGACGGGA
AGCAGGCCTGCATTCTCATGATCAAAGCCCTGGAACTTGACCCCAACTTATACAGGATAGGGCAGAGCAAAATCTTCTTCCGAACTGGCG
TCCTGGCCCACCTAGAGGAGGAGCGAGATTTGAAGATCACCGATGTCATCATGGCCTTCCAGGCGATGTGTCGTGGCTACTTGGCCAGAA
AGGCTTTTGCCAAGAGGCAGCAGCAGCTGACCGCCATGAAGGTGATTCAGAGGAACTGCGCCGCCTACCTCAAGCTGCGGAACTGGCAGT
GGTGGAGGCTTTTCACCAAAGTGAAGCCACTGCTGCAGGTGACACGGCAGGAGGAGGAGATGCAGGCCAAGGAGGATGAACTGCAGAAGA
CCAAGGAGCGGCAGCAGAAGGCAGAGAATGAGCTTAAGGAGCTGGAACAGAAGCACTCGCAGCTGACCGAGGAGAAGAACCTGCTACAGG
AACAGCTGCAGGCAGAGACAGAGCTGTATGCAGAGGCTGAGGAGATGCGGGTGCGGCTGGCGGCCAAGAAGCAGGAGCTGGAGGAGATAC
TGCATGAGATGGAGGCCCGCCTGGAGGAGGAGGAAGACAGGGGCCAGCAGCTACAGGCTGAAAGGAAGAAGATGGCCCAGCAGATGCTGG
ACCTTGAAGAACAGCTGGAGGAGGAGGAAGCTGCCAGGCAGAAGCTGCAACTTGAGAAGGTCACGGCTGAGGCCAAGATCAAGAAACTGG
AGGATGAGATCCTGGTCATGGATGATCAGAACAATAAACTATCAAAAGAACGAAAACTCCTTGAGGAGAGGATTAGTGACTTAACGACAA
ATCTTGCAGAAGAGGAAGAAAAGGCCAAGAATCTTACCAAGCTGAAAAACAAGCATGAATCTATGATTTCAGAACTGGAAGTGCGGCTAA
AGAAGGAAGAGAAGAGCCGACAGGAGCTGGAGAAGCTGAAACGGAAGCTGGAGGGTGATGCCAGCGACTTCCACGAGCAGATCGCTGACC
TCCAGGCGCAGATCGCAGAGCTCAAGATGCAGCTGGCCAAGAAGGAGGAGGAGCTGCAGGCGGCCCTGGCCAGGCTTGACGATGAAATCG
CTCAGAAGAACAATGCCCTGAAGAAGATCCGGGAGCTGGAGGGCCACATCTCAGACCTCCAGGAGGACCTGGACTCAGAGCGGGCCGCCA
GGAACAAGGCTGAAAAGCAGAAGCGAGACCTCGGCGAGGAGCTGGAGGCCCTAAAGACAGAGCTGGAAGACACACTGGACAGCACAGCCA
CTCAGCAGGAGCTCAGGGCCAAGAGGGAGCAGGAGGTGACGGTGCTGAAGAAGGCCCTGGATGAAGAGACGCGGTCCCATGAGGCTCAGG
TCCAGGAGATGAGGCAGAAACACGCACAGGCGGTGGAGGAGCTCACAGAGCAGCTTGAGCAGTTCAAGAGGGCCAAGGCGAACCTAGACA
AGAATAAGCAGACGCTGGAGAAAGAGAACGCAGACCTGGCCGGGGAGCTGCGGGTCCTGGGCCAGGCCAAGCAGGAGGTGGAACATAAGA
AGAAGAAGCTGGAGGCGCAGGTGCAGGAGCTGCAGTCCAAGTGCAGCGATGGGGAGCGGGCCCGGGCGGAGCTCAATGACAAAGTCCACA
AGCTGCAGAATGAAGTTGAGAGCGTCACAGGGATGCTTAACGAGGCCGAGGGGAAGGCCATTAAGCTGGCCAAGGACGTGGCGTCCCTCA
GTTCCCAGCTCCAGGACACCCAGGAGCTGCTTCAAGAAGAAACCCGGCAGAAGCTCAACGTGTCTACGAAGCTGCGCCAGCTGGAGGAGG
AGCGGAACAGCCTGCAAGACCAGCTGGACGAGGAGATGGAGGCCAAGCAGAACCTGGAGCGCCACATCTCCACTCTCAACATCCAGCTCT
CCGACTCGAAGAAGAAGCTGCAGGACTTTGCCAGCACCGTGGAAGCTCTGGAAGAGGGGAAGAAGAGGTTCCAGAAGGAGATCGAGAACC
TCACCCAGCAGTACGAGGAGAAGGCGGCCGCTTATGATAAACTGGAAAAGACCAAGAACAGGCTTCAGCAGGAGCTGGACGACCTGGTTG
TTGATTTGGACAACCAGCGGCAACTCGTGTCCAACCTGGAAAAGAAGCAGAGGAAATTTGATCAGTTGTTAGCCGAGGAGAAAAACATCT
CTTCCAAATACGCGGATGAGAGGGACAGAGCTGAGGCAGAAGCCAGGGAGAAGGAAACCAAGGCCCTGTCCCTGGCTCGGGCCCTTGAAG
AGGCCTTGGAAGCCAAAGAGGAACTCGAGCGGACCAACAAAATGCTCAAAGCCGAAATGGAAGACCTGGTCAGCTCCAAGGATGACGTGG
GCAAGAACGTCCATGAGCTGGAGAAGTCCAAGCGGGCCCTGGAGACCCAGATGGAGGAGATGAAGACGCAGCTGGAAGAGCTGGAGGACG
AGCTGCAAGCCACGGAGGACGCCAAACTGCGGCTGGAAGTCAACATGCAGGCGCTCAAGGGCCAGTTCGAAAGGGATCTCCAAGCCCGGG
ACGAGCAGAATGAGGAGAAGAGGAGGCAACTGCAGAGACAGCTTCACGAGTATGAGACGGAACTGGAAGACGAGCGAAAGCAACGTGCCC
TGGCAGCTGCAGCAAAGAAGAAGCTGGAAGGGGACCTGAAAGACCTGGAGCTTCAGGCCGACTCTGCCATCAAGGGGAGGGAGGAAGCCA
TCAAGCAGCTACGCAAACTGCAGGCTCAGATGAAGGACTTTCAAAGAGAGCTGGAAGATGCCCGTGCCTCCAGAGATGAGATCTTTGCCA
CAGCCAAAGAGAATGAGAAGAAAGCCAAGAGCTTGGAAGCAGACCTCATGCAGCTACAAGAGGACCTCGCCGCCGCTGAGAGGGCTCGCA
AACAAGCGGACCTCGAGAAGGAGGAACTGGCAGAGGAGCTGGCCAGTAGCCTGTCGGGAAGGAACGCACTCCAGGACGAGAAGCGCCGCC
TGGAGGCCCGGATCGCCCAGCTGGAGGAGGAGCTGGAGGAGGAGCAGGGCAACATGGAGGCCATGAGCGACCGGGTCCGCAAAGCCACAC
AGCAGGCCGAGCAGCTCAGCAACGAGCTGGCCACAGAGCGCAGCACGGCCCAGAAGAATGAGAGTGCCCGGCAGCAGCTCGAGCGGCAGA
ACAAGGAGCTCCGGAGCAAGCTCCACGAGATGGAGGGGGCCGTCAAGTCCAAGTTCAAGTCCACCATCGCGGCGCTGGAGGCCAAGATTG
CACAGCTGGAGGAGCAGGTCGAGCAGGAGGCCAGAGAGAAACAGGCGGCCACCAAGTCGCTGAAGCAGAAAGACAAGAAGCTGAAGGAAA
TCTTGCTGCAGGTGGAGGACGAGCGCAAGATGGCCGAGCAGTACAAGGAGCAGATCCAGGAAAGCGAGCACATGAAGGTGGAGAACAGCG
AGAATGGCAGCAAGCTCACCATCCTGGCCGCGCGCCAGGAGCACTGCGGCTGCTACACACTGCTGGTGGAGAACAAGCTGGGCAGCAGGC
AGGCCCAGGTCAACCTCACTGTCGTGGATAAGCCAGACCCCCCAGCTGGCACACCTTGTGCCTCTGACATTCGGAGCTCCTCACTGACCC
TGTCCTGGTATGGCTCCTCATATGATGGGGGCAGTGCTGTACAGTCCTACAGCATCGAGATCTGGGACTCAGCCAACAAGACGTGGAAGG
AACTAGCCACATGCCGCAGCACCTCTTTCAACGTCCAGGACCTGCTGCCTGACCACGAATATAAGTTCCGTGTACGTGCAATCAACGTGT
ATGGAACCAGTGAGCCAAGCCAGGAGTCTGAACTCACAACGGTAGGAGAGAAACCTGAAGAGCCGAAGGATGAAGTGGAGGTGTCAGATG
ATGATGAGAAGGAGCCCGAGGTTGATTACCGGACAGTGACAATCAATACTGAACAAAAAGTATCTGACTTCTACGACATTGAGGAGAGAT
TAGGATCTGGGAAATTTGGACAGGTCTTTCGACTTGTAGAAAAGAAAACTCGAAAAGTCTGGGCAGGGAAGTTCTTCAAGGCATATTCAG
CAAAAGAGAAAGAGAATATCCGGCAGGAGATTAGCATCATGAACTGCCTCCACCACCCTAAGCTGGTCCAGTGTGTGGATGCCTTTGAAG
AAAAGGCCAACATCGTCATGGTCCTGGAGATCGTGTCAGGAGGGGAGCTGTTTGAGCGCATCATTGACGAGGACTTTGAGCTGACGGAGC
GTGAGTGCATCAAGTACATGCGGCAGATCTCGGAGGGAGTGGAGTACATCCACAAGCAGGGCATCGTGCACCTGGACCTCAAGCCGGAGA
ACATCATGTGTGTCAACAAGACGGGCACCAGGATCAAGCTCATCGACTTTGGTCTGGCCAGGAGGCTGGAGAATGCGGGGTCTCTGAAGG
TCCTCTTTGGCACCCCAGAATTTGTGGCTCCTGAAGTGATCAACTATGAGCCCATCGGCTACGCCACAGACATGTGGAGCATCGGGGTCA
TCTGCTACATCCTAAACCGCCTGGACTGCACGCAGTGCCTTCAGCATCCATGGCTAATGAAAGATACCAAGAACATGGAGGCCAAGAAAC
TCTCCAAGGACCGGATGAAGAAGTACATGGCAAGAAGGAAATGGCAGAAAACGGGCAATGCTGTGAGAGCCATTGGAAGACTGTCCTCTA
TGGCAATGATCTCAGGGCTCAGTGGCAGGAAATCCTCAACAGGGTCACCAACCAGCCCGCTCAATGCAGAAAAACTAGAATCTGAAGAAG
ATGTGTCCCAAGCTTTCCTTGAGGCTGTTGCTGAGGAAAAGCCTCATGTAAAACCCTATTTCTCTAAGACCATTCGCGATTTAGAAGTTG
TGGAGGGAAGTGCTGCTAGATTTGACTGCAAGATTGAAGGATACCCAGACCCCGAGGTTGTCTGGTTCAAAGATGACCAGTCAATCAGGG
AGTCCCGCCACTTCCAGATAGACTACGATGAGGACGGGAACTGCTCTTTAATTATTAGTGATGTTTGCGGGGATGACGATGCCAAGTACA
CCTGCAAGGCTGTCAACAGTCTTGGAGAAGCCACCTGCACAGCAGAGCTCATTGTGGAAACGATGGAGGAAGGTGAAGGGGAAGGGGAAG
AGGAAGAAGAGTGAAACAAAGCCAGAGAAAAGCAGTTTCTAAGTCATATTAAAAGGACTATTTCTCTAAAACTCAAAAAAAAAAAAAAAA
CTCAAGATAGTAAAAGCACCTAGTGTGATAGATTATCGGTTAGGTCATTTGTGGGTTGATTCTTCAGAAACAGCAGTTGATACCTAGCAG
CGTTATTGATGGGCATTAATCTATGTTAGTTGGCACCTTAAGATACTAGTGCAGCTAGATTTCATTTAGGGAAATCACCAGTAACTTGAC
TGACCAATTGATTTTAGAGAGAAAGTAACCAAACCAAATATTTATCTGGGCAAAGTCATAAATTCTCCACTTGAATGCGCTCATGAAAAA
TAAGGCCAAAACAAGAGTTCTGGGCCACAGCTCAGCCCAGAGGGTTCCTGGGGATGGGAGGCCTCTCTCTCCCCACCCCCTGACTCTAGA
GAACTGGGTTTTCTCCCAGTACTCCAGCAATTCATTTCTGAAAGCAGTTGAGCCACTTTATTCCAAAGTACACTGCAGATGTTCAAACTC
TCCATTTCTCTTTCCCCTTCCACCTGCCAGTTTTGCTGACTCTCAACTTGTCATGAGTGTAAGCATTAAGGACATTATGCTTCTTCGATT
CTGAAGACAGGTCCCTGCTCATGGATGACTCTGGCTTCCTTAGGAAAATATTTTTCTTCCAAAATCAGTAGGAAATCTAAACTTATCCCC
TCTTTGCAGATGTCTAGCAGCTTCAGACATTTGGTTAAGAACCCATGGGAAAAAAAAAATCCTTGCTAATGTGGTTTCCTTTGTAAACCA
GGATTCTTATTTGTGCTGTTATAGAATATCAGCTCTGAACGTGTGGTAAAGATTTTTGTGTTTGAATATAGGAGAAATCAGTTTGCTGAA
AAGTTAGTCTTAATTATCTATTGGCCACGATGAAACAGATTTCAACTGATAAAGAGCTGGAGAACTCCATGTACTTTGGAATCTCCTCCA
AGATAGCCAGAGTTTAATACATCTTCATTCTCAACACTCTCCAAAGAACTTGACCTACCTTATGGGTTCCATATTTTTCTTCTTAAATGT
GCATCAATCATGCCTTGCCCCCAACCTTTAAATATATTCTTAGACCTGGTAAATGCACTCAGACTTGCGTCTTTAGGAATTTTTAACTTT
CTTTCACTACATTGGCACTTAAATTTTTTCTTTATAAAGCTTTTTGAAGGTCATAAACAAAGACCATAATTGATGATAGACCTAATACAT
TTCCTCTGTGTGTGTGTGTAACATTCCAAATACTTTTTTTTTCTTTTCCACTGTTTGTAAGGTGCAACAATTTAATATTTTTAAGGGACT
TTTTAAGAGTTCCTTAAGAACCAATTTAAAATTACTTCAGTGCAATCCTACACAGTATCAACATTAGAATTTTGATATTAGTCTTATGTT
ATCTTCCATTCTATTTTTATCTGCTTTTTGCTGCTAGTTTCAAACTGCCAGTATTTTTCCTTTTGCTTTTAAAATAGTTACAATATTTTT
CATGATAGCCACAGTATTGCCACAGTTTATTATAATAAAGGGTTTTTATTTGATTTAGCGCATTCAAAGCTTTTTTCTATCACTTTTGTG
TTCAGAATATAACCTTTGTGTGCGTGTATGTTGTGTGTGTGCATGTGTGGCGTATATGTGTGTTACAGGTTAATGCCTTCTTGGAATTGT
GTTAATGTTCTCTTGGTTTATTATGCCATCAGAATGGTAAATGAGAACACTACAACTGTAGTCAGCTCACAATTTTTAAATAAAGGATAC

>56300_56300_4_MYH11-MYLK_MYH11_chr16_15809021_ENST00000576790_MYLK_chr3_123383105_ENST00000359169_length(amino acids)=2466AA_BP=1880
MEIWDQQGTMAQKGQLSDDEKFLFVDKNFINSPVAQADWAAKRLVWVPSEKQGFEAASIKEEKGDEVVVELVENGKKVTVGKDDIQKMNP
PKFSKVEDMAELTCLNEASVLHNLRERYFSGLIYTYSGLFCVVVNPYKHLPIYSEKIVDMYKGKKRHEMPPHIYAIADTAYRSMLQDRED
QSILCTGESGAGKTENTKKVIQYLAVVASSHKGKKDTSITGELEKQLLQANPILEAFGNAKTVKNDNSSRFGKFIRINFDVTGYIVGANI
ETYLLEKSRAIRQARDERTFHIFYYMIAGAKEKMRSDLLLEGFNNYTFLSNGFVPIPAAQDDEMFQETVEAMAIMGFSEEEQLSILKVVS
SVLQLGNIVFKKERNTDQASMPDNTAAQKVCHLMGINVTDFTRSILTPRIKVGRDVVQKAQTKEQADFAVEALAKATYERLFRWILTRVN
KALDKTHRQGASFLGILDIAGFEIFEVNSFEQLCINYTNEKLQQLFNHTMFILEQEEYQREGIEWNFIDFGLDLQPCIELIERPNNPPGV
LALLDEECWFPKATDKSFVEKLCTEQGSHPKFQKPKQLKDKTEFSIIHYAGKVDYNASAWLTKNMDPLNDNVTSLLNASSDKFVADLWKD
VDRIVGLDQMAKMTESSLPSASKTKKGMFRTVGQLYKEQLGKLMTTLRNTTPNFVRCIIPNHEKRSGKLDAFLVLEQLRCNGVLEGIRIC
RQGFPNRIVFQEFRQRYEILAANAIPKGFMDGKQACILMIKALELDPNLYRIGQSKIFFRTGVLAHLEEERDLKITDVIMAFQAMCRGYL
ARKAFAKRQQQLTAMKVIQRNCAAYLKLRNWQWWRLFTKVKPLLQVTRQEEEMQAKEDELQKTKERQQKAENELKELEQKHSQLTEEKNL
LQEQLQAETELYAEAEEMRVRLAAKKQELEEILHEMEARLEEEEDRGQQLQAERKKMAQQMLDLEEQLEEEEAARQKLQLEKVTAEAKIK
KLEDEILVMDDQNNKLSKERKLLEERISDLTTNLAEEEEKAKNLTKLKNKHESMISELEVRLKKEEKSRQELEKLKRKLEGDASDFHEQI
ADLQAQIAELKMQLAKKEEELQAALARLDDEIAQKNNALKKIRELEGHISDLQEDLDSERAARNKAEKQKRDLGEELEALKTELEDTLDS
TATQQELRAKREQEVTVLKKALDEETRSHEAQVQEMRQKHAQAVEELTEQLEQFKRAKANLDKNKQTLEKENADLAGELRVLGQAKQEVE
HKKKKLEAQVQELQSKCSDGERARAELNDKVHKLQNEVESVTGMLNEAEGKAIKLAKDVASLSSQLQDTQELLQEETRQKLNVSTKLRQL
EEERNSLQDQLDEEMEAKQNLERHISTLNIQLSDSKKKLQDFASTVEALEEGKKRFQKEIENLTQQYEEKAAAYDKLEKTKNRLQQELDD
LVVDLDNQRQLVSNLEKKQRKFDQLLAEEKNISSKYADERDRAEAEAREKETKALSLARALEEALEAKEELERTNKMLKAEMEDLVSSKD
DVGKNVHELEKSKRALETQMEEMKTQLEELEDELQATEDAKLRLEVNMQALKGQFERDLQARDEQNEEKRRQLQRQLHEYETELEDERKQ
RALAAAAKKKLEGDLKDLELQADSAIKGREEAIKQLRKLQAQMKDFQRELEDARASRDEIFATAKENEKKAKSLEADLMQLQEDLAAAER
ARKQADLEKEELAEELASSLSGRNALQDEKRRLEARIAQLEEELEEEQGNMEAMSDRVRKATQQAEQLSNELATERSTAQKNESARQQLE
RQNKELRSKLHEMEGAVKSKFKSTIAALEAKIAQLEEQVEQEAREKQAATKSLKQKDKKLKEILLQVEDERKMAEQYKEQIQESEHMKVE
NSENGSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTVVDKPDPPAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSIEIWDSANKT
WKELATCRSTSFNVQDLLPDHEYKFRVRAINVYGTSEPSQESELTTVGEKPEEPKDEVEVSDDDEKEPEVDYRTVTINTEQKVSDFYDIE
ERLGSGKFGQVFRLVEKKTRKVWAGKFFKAYSAKEKENIRQEISIMNCLHHPKLVQCVDAFEEKANIVMVLEIVSGGELFERIIDEDFEL
TERECIKYMRQISEGVEYIHKQGIVHLDLKPENIMCVNKTGTRIKLIDFGLARRLENAGSLKVLFGTPEFVAPEVINYEPIGYATDMWSI
GVICYILNRLDCTQCLQHPWLMKDTKNMEAKKLSKDRMKKYMARRKWQKTGNAVRAIGRLSSMAMISGLSGRKSSTGSPTSPLNAEKLES
EEDVSQAFLEAVAEEKPHVKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDVCGDDDA

--------------------------------------------------------------
>56300_56300_5_MYH11-MYLK_MYH11_chr16_15809021_ENST00000576790_MYLK_chr3_123383105_ENST00000360304_length(transcript)=9444nt_BP=5723nt
GCAGGGAGATTTGGACGCTCCGGCCTGGGAGGTGCGTCAGATCCGAGCTCGCCATCCAGTTTCCTCTCCACTAGTCCCCCCAGTTGGAGA
TCTGGGACCAACAAGGCACCATGGCGCAGAAGGGCCAACTCAGTGACGATGAGAAGTTCCTCTTTGTGGACAAAAACTTCATCAACAGCC
CAGTGGCCCAGGCTGACTGGGCCGCCAAGAGACTCGTCTGGGTCCCCTCGGAGAAGCAGGGCTTCGAGGCAGCCAGCATTAAGGAGGAGA
AGGGGGATGAGGTGGTTGTGGAGCTGGTGGAGAATGGCAAGAAGGTCACGGTTGGGAAAGATGACATCCAGAAGATGAACCCACCCAAGT
TCTCCAAGGTGGAGGACATGGCGGAGCTGACGTGCCTCAACGAAGCCTCCGTGCTACACAACCTGAGGGAGCGGTACTTCTCAGGGCTAA
TATATACGTACTCTGGCCTCTTCTGCGTGGTGGTCAACCCCTATAAACACCTGCCCATCTACTCGGAGAAGATCGTCGACATGTACAAGG
GCAAGAAGAGGCACGAGATGCCGCCTCACATCTACGCCATCGCAGACACGGCCTACCGGAGCATGCTTCAAGATCGGGAGGACCAGTCCA
TTCTATGCACAGGCGAGTCTGGAGCCGGGAAAACCGAAAACACCAAGAAGGTCATTCAGTACCTGGCCGTGGTGGCCTCCTCCCACAAGG
GCAAGAAAGACACAAGTATCACGGGAGAGCTGGAAAAGCAGCTTCTACAAGCAAACCCGATTCTGGAGGCTTTCGGCAACGCCAAAACAG
TGAAGAACGACAACTCCTCACGATTCGGCAAATTCATCCGCATCAACTTCGACGTCACGGGTTACATCGTGGGAGCCAACATTGAGACCT
ATCTGCTAGAAAAATCACGGGCAATTCGCCAAGCCAGAGACGAGAGGACATTCCACATCTTTTACTACATGATTGCTGGAGCCAAGGAGA
AGATGAGAAGTGACTTGCTTTTGGAGGGCTTCAACAACTACACCTTCCTCTCCAATGGCTTTGTGCCCATCCCAGCAGCCCAGGATGATG
AGATGTTCCAGGAAACCGTGGAGGCCATGGCAATCATGGGTTTCAGCGAGGAGGAGCAGCTATCCATATTGAAGGTGGTATCATCGGTCC
TGCAGCTTGGAAATATCGTCTTCAAGAAGGAAAGAAACACAGACCAGGCGTCCATGCCAGATAACACAGCTGCTCAGAAAGTTTGCCACC
TCATGGGAATTAATGTGACAGATTTCACCAGATCCATCCTCACTCCTCGTATCAAGGTTGGGCGAGATGTGGTACAGAAAGCTCAGACAA
AAGAACAGGCTGACTTTGCTGTAGAGGCTTTGGCCAAGGCAACATATGAGCGCCTTTTCCGCTGGATACTCACCCGCGTGAACAAAGCCC
TGGACAAGACCCATCGGCAAGGGGCTTCCTTCCTGGGGATCCTGGATATAGCTGGATTTGAGATCTTTGAGGTGAACTCCTTCGAGCAGC
TGTGCATCAACTACACCAACGAGAAGCTGCAGCAGCTCTTCAACCACACCATGTTCATCCTGGAGCAGGAGGAGTACCAGCGCGAGGGCA
TCGAGTGGAACTTCATCGACTTTGGGCTGGACCTACAGCCCTGCATCGAGCTCATCGAGCGACCGAACAACCCTCCAGGTGTGCTGGCCC
TGCTGGACGAGGAATGCTGGTTCCCCAAAGCCACGGACAAGTCTTTCGTGGAGAAGCTGTGCACGGAGCAGGGCAGCCACCCCAAGTTCC
AGAAGCCCAAGCAGCTCAAGGACAAGACTGAGTTCTCCATCATCCATTATGCTGGGAAGGTGGACTATAATGCGAGTGCCTGGCTGACCA
AGAATATGGACCCGCTGAATGACAACGTGACTTCCCTGCTCAATGCCTCCTCCGACAAGTTTGTGGCCGACCTGTGGAAGGACGTGGACC
GCATCGTGGGCCTGGACCAGATGGCCAAGATGACGGAGAGCTCGCTGCCCAGCGCCTCCAAGACCAAGAAGGGCATGTTCCGCACAGTGG
GGCAGCTGTACAAGGAGCAGCTGGGCAAGCTGATGACCACGCTACGCAACACCACGCCCAACTTCGTGCGCTGCATCATCCCCAACCACG
AGAAGAGGTCCGGCAAGCTGGATGCGTTCCTGGTGCTGGAGCAGCTGCGGTGCAATGGGGTGCTGGAAGGCATTCGCATCTGCCGGCAGG
GCTTCCCCAACCGGATCGTCTTCCAGGAGTTCCGCCAACGCTACGAGATCCTGGCGGCGAATGCCATCCCCAAAGGCTTCATGGACGGGA
AGCAGGCCTGCATTCTCATGATCAAAGCCCTGGAACTTGACCCCAACTTATACAGGATAGGGCAGAGCAAAATCTTCTTCCGAACTGGCG
TCCTGGCCCACCTAGAGGAGGAGCGAGATTTGAAGATCACCGATGTCATCATGGCCTTCCAGGCGATGTGTCGTGGCTACTTGGCCAGAA
AGGCTTTTGCCAAGAGGCAGCAGCAGCTGACCGCCATGAAGGTGATTCAGAGGAACTGCGCCGCCTACCTCAAGCTGCGGAACTGGCAGT
GGTGGAGGCTTTTCACCAAAGTGAAGCCACTGCTGCAGGTGACACGGCAGGAGGAGGAGATGCAGGCCAAGGAGGATGAACTGCAGAAGA
CCAAGGAGCGGCAGCAGAAGGCAGAGAATGAGCTTAAGGAGCTGGAACAGAAGCACTCGCAGCTGACCGAGGAGAAGAACCTGCTACAGG
AACAGCTGCAGGCAGAGACAGAGCTGTATGCAGAGGCTGAGGAGATGCGGGTGCGGCTGGCGGCCAAGAAGCAGGAGCTGGAGGAGATAC
TGCATGAGATGGAGGCCCGCCTGGAGGAGGAGGAAGACAGGGGCCAGCAGCTACAGGCTGAAAGGAAGAAGATGGCCCAGCAGATGCTGG
ACCTTGAAGAACAGCTGGAGGAGGAGGAAGCTGCCAGGCAGAAGCTGCAACTTGAGAAGGTCACGGCTGAGGCCAAGATCAAGAAACTGG
AGGATGAGATCCTGGTCATGGATGATCAGAACAATAAACTATCAAAAGAACGAAAACTCCTTGAGGAGAGGATTAGTGACTTAACGACAA
ATCTTGCAGAAGAGGAAGAAAAGGCCAAGAATCTTACCAAGCTGAAAAACAAGCATGAATCTATGATTTCAGAACTGGAAGTGCGGCTAA
AGAAGGAAGAGAAGAGCCGACAGGAGCTGGAGAAGCTGAAACGGAAGCTGGAGGGTGATGCCAGCGACTTCCACGAGCAGATCGCTGACC
TCCAGGCGCAGATCGCAGAGCTCAAGATGCAGCTGGCCAAGAAGGAGGAGGAGCTGCAGGCGGCCCTGGCCAGGCTTGACGATGAAATCG
CTCAGAAGAACAATGCCCTGAAGAAGATCCGGGAGCTGGAGGGCCACATCTCAGACCTCCAGGAGGACCTGGACTCAGAGCGGGCCGCCA
GGAACAAGGCTGAAAAGCAGAAGCGAGACCTCGGCGAGGAGCTGGAGGCCCTAAAGACAGAGCTGGAAGACACACTGGACAGCACAGCCA
CTCAGCAGGAGCTCAGGGCCAAGAGGGAGCAGGAGGTGACGGTGCTGAAGAAGGCCCTGGATGAAGAGACGCGGTCCCATGAGGCTCAGG
TCCAGGAGATGAGGCAGAAACACGCACAGGCGGTGGAGGAGCTCACAGAGCAGCTTGAGCAGTTCAAGAGGGCCAAGGCGAACCTAGACA
AGAATAAGCAGACGCTGGAGAAAGAGAACGCAGACCTGGCCGGGGAGCTGCGGGTCCTGGGCCAGGCCAAGCAGGAGGTGGAACATAAGA
AGAAGAAGCTGGAGGCGCAGGTGCAGGAGCTGCAGTCCAAGTGCAGCGATGGGGAGCGGGCCCGGGCGGAGCTCAATGACAAAGTCCACA
AGCTGCAGAATGAAGTTGAGAGCGTCACAGGGATGCTTAACGAGGCCGAGGGGAAGGCCATTAAGCTGGCCAAGGACGTGGCGTCCCTCA
GTTCCCAGCTCCAGGACACCCAGGAGCTGCTTCAAGAAGAAACCCGGCAGAAGCTCAACGTGTCTACGAAGCTGCGCCAGCTGGAGGAGG
AGCGGAACAGCCTGCAAGACCAGCTGGACGAGGAGATGGAGGCCAAGCAGAACCTGGAGCGCCACATCTCCACTCTCAACATCCAGCTCT
CCGACTCGAAGAAGAAGCTGCAGGACTTTGCCAGCACCGTGGAAGCTCTGGAAGAGGGGAAGAAGAGGTTCCAGAAGGAGATCGAGAACC
TCACCCAGCAGTACGAGGAGAAGGCGGCCGCTTATGATAAACTGGAAAAGACCAAGAACAGGCTTCAGCAGGAGCTGGACGACCTGGTTG
TTGATTTGGACAACCAGCGGCAACTCGTGTCCAACCTGGAAAAGAAGCAGAGGAAATTTGATCAGTTGTTAGCCGAGGAGAAAAACATCT
CTTCCAAATACGCGGATGAGAGGGACAGAGCTGAGGCAGAAGCCAGGGAGAAGGAAACCAAGGCCCTGTCCCTGGCTCGGGCCCTTGAAG
AGGCCTTGGAAGCCAAAGAGGAACTCGAGCGGACCAACAAAATGCTCAAAGCCGAAATGGAAGACCTGGTCAGCTCCAAGGATGACGTGG
GCAAGAACGTCCATGAGCTGGAGAAGTCCAAGCGGGCCCTGGAGACCCAGATGGAGGAGATGAAGACGCAGCTGGAAGAGCTGGAGGACG
AGCTGCAAGCCACGGAGGACGCCAAACTGCGGCTGGAAGTCAACATGCAGGCGCTCAAGGGCCAGTTCGAAAGGGATCTCCAAGCCCGGG
ACGAGCAGAATGAGGAGAAGAGGAGGCAACTGCAGAGACAGCTTCACGAGTATGAGACGGAACTGGAAGACGAGCGAAAGCAACGTGCCC
TGGCAGCTGCAGCAAAGAAGAAGCTGGAAGGGGACCTGAAAGACCTGGAGCTTCAGGCCGACTCTGCCATCAAGGGGAGGGAGGAAGCCA
TCAAGCAGCTACGCAAACTGCAGGCTCAGATGAAGGACTTTCAAAGAGAGCTGGAAGATGCCCGTGCCTCCAGAGATGAGATCTTTGCCA
CAGCCAAAGAGAATGAGAAGAAAGCCAAGAGCTTGGAAGCAGACCTCATGCAGCTACAAGAGGACCTCGCCGCCGCTGAGAGGGCTCGCA
AACAAGCGGACCTCGAGAAGGAGGAACTGGCAGAGGAGCTGGCCAGTAGCCTGTCGGGAAGGAACGCACTCCAGGACGAGAAGCGCCGCC
TGGAGGCCCGGATCGCCCAGCTGGAGGAGGAGCTGGAGGAGGAGCAGGGCAACATGGAGGCCATGAGCGACCGGGTCCGCAAAGCCACAC
AGCAGGCCGAGCAGCTCAGCAACGAGCTGGCCACAGAGCGCAGCACGGCCCAGAAGAATGAGAGTGCCCGGCAGCAGCTCGAGCGGCAGA
ACAAGGAGCTCCGGAGCAAGCTCCACGAGATGGAGGGGGCCGTCAAGTCCAAGTTCAAGTCCACCATCGCGGCGCTGGAGGCCAAGATTG
CACAGCTGGAGGAGCAGGTCGAGCAGGAGGCCAGAGAGAAACAGGCGGCCACCAAGTCGCTGAAGCAGAAAGACAAGAAGCTGAAGGAAA
TCTTGCTGCAGGTGGAGGACGAGCGCAAGATGGCCGAGCAGTACAAGGAGCAGATCCAGGAAAGCGAGCACATGAAGGTGGAGAACAGCG
AGAATGGCAGCAAGCTCACCATCCTGGCCGCGCGCCAGGAGCACTGCGGCTGCTACACACTGCTGGTGGAGAACAAGCTGGGCAGCAGGC
AGGCCCAGGTCAACCTCACTGTCGTGGATAAGCCAGACCCCCCAGCTGGCACACCTTGTGCCTCTGACATTCGGAGCTCCTCACTGACCC
TGTCCTGGTATGGCTCCTCATATGATGGGGGCAGTGCTGTACAGTCCTACAGCATCGAGATCTGGGACTCAGCCAACAAGACGTGGAAGG
AACTAGCCACATGCCGCAGCACCTCTTTCAACGTCCAGGACCTGCTGCCTGACCACGAATATAAGTTCCGTGTACGTGCAATCAACGTGT
ATGGAACCAGTGAGCCAAGCCAGGAGTCTGAACTCACAACGGTAGGAGAGAAACCTGAAGAGCCGAAGGATGAAGTGGAGGTGTCAGATG
ATGATGAGAAGGAGCCCGAGGTTGATTACCGGACAGTGACAATCAATACTGAACAAAAAGTATCTGACTTCTACGACATTGAGGAGAGAT
TAGGATCTGGGAAATTTGGACAGGTCTTTCGACTTGTAGAAAAGAAAACTCGAAAAGTCTGGGCAGGGAAGTTCTTCAAGGCATATTCAG
CAAAAGAGAAAGAGAATATCCGGCAGGAGATTAGCATCATGAACTGCCTCCACCACCCTAAGCTGGTCCAGTGTGTGGATGCCTTTGAAG
AAAAGGCCAACATCGTCATGGTCCTGGAGATCGTGTCAGGAGGGGAGCTGTTTGAGCGCATCATTGACGAGGACTTTGAGCTGACGGAGC
GTGAGTGCATCAAGTACATGCGGCAGATCTCGGAGGGAGTGGAGTACATCCACAAGCAGGGCATCGTGCACCTGGACCTCAAGCCGGAGA
ACATCATGTGTGTCAACAAGACGGGCACCAGGATCAAGCTCATCGACTTTGGTCTGGCCAGGAGGCTGGAGAATGCGGGGTCTCTGAAGG
TCCTCTTTGGCACCCCAGAATTTGTGGCTCCTGAAGTGATCAACTATGAGCCCATCGGCTACGCCACAGACATGTGGAGCATCGGGGTCA
TCTGCTACATCCTAGTCAGTGGCCTTTCCCCCTTCATGGGAGACAACGATAACGAAACCTTGGCCAACGTTACCTCAGCCACCTGGGACT
TCGACGACGAGGCATTCGATGAGATCTCCGACGATGCCAAGGATTTCATCAGCAATCTGCTGAAGAAAGATATGAAAAACCGCCTGGACT
GCACGCAGTGCCTTCAGCATCCATGGCTAATGAAAGATACCAAGAACATGGAGGCCAAGAAACTCTCCAAGGACCGGATGAAGAAGTACA
TGGCAAGAAGGAAATGGCAGAAAACGGGCAATGCTGTGAGAGCCATTGGAAGACTGTCCTCTATGGCAATGATCTCAGGGCTCAGTGGCA
GGAAATCCTCAACAGGGTCACCAACCAGCCCGCTCAATGCAGAAAAACTAGAATCTGAAGAAGATGTGTCCCAAGCTTTCCTTGAGGCTG
TTGCTGAGGAAAAGCCTCATGTAAAACCCTATTTCTCTAAGACCATTCGCGATTTAGAAGTTGTGGAGGGAAGTGCTGCTAGATTTGACT
GCAAGATTGAAGGATACCCAGACCCCGAGGTTGTCTGGTTCAAAGATGACCAGTCAATCAGGGAGTCCCGCCACTTCCAGATAGACTACG
ATGAGGACGGGAACTGCTCTTTAATTATTAGTGATGTTTGCGGGGATGACGATGCCAAGTACACCTGCAAGGCTGTCAACAGTCTTGGAG
AAGCCACCTGCACAGCAGAGCTCATTGTGGAAACGATGGAGGAAGGTGAAGGGGAAGGGGAAGAGGAAGAAGAGTGAAACAAAGCCAGAG
AAAAGCAGTTTCTAAGTCATATTAAAAGGACTATTTCTCTAAAACTCAAAAAAAAAAAAAAAACTCAAGATAGTAAAAGCACCTAGTGTG
ATAGATTATCGGTTAGGTCATTTGTGGGTTGATTCTTCAGAAACAGCAGTTGATACCTAGCAGCGTTATTGATGGGCATTAATCTATGTT
AGTTGGCACCTTAAGATACTAGTGCAGCTAGATTTCATTTAGGGAAATCACCAGTAACTTGACTGACCAATTGATTTTAGAGAGAAAGTA
ACCAAACCAAATATTTATCTGGGCAAAGTCATAAATTCTCCACTTGAATGCGCTCATGAAAAATAAGGCCAAAACAAGAGTTCTGGGCCA
CAGCTCAGCCCAGAGGGTTCCTGGGGATGGGAGGCCTCTCTCTCCCCACCCCCTGACTCTAGAGAACTGGGTTTTCTCCCAGTACTCCAG
CAATTCATTTCTGAAAGCAGTTGAGCCACTTTATTCCAAAGTACACTGCAGATGTTCAAACTCTCCATTTCTCTTTCCCCTTCCACCTGC
CAGTTTTGCTGACTCTCAACTTGTCATGAGTGTAAGCATTAAGGACATTATGCTTCTTCGATTCTGAAGACAGGTCCCTGCTCATGGATG
ACTCTGGCTTCCTTAGGAAAATATTTTTCTTCCAAAATCAGTAGGAAATCTAAACTTATCCCCTCTTTGCAGATGTCTAGCAGCTTCAGA
CATTTGGTTAAGAACCCATGGGAAAAAAAAAATCCTTGCTAATGTGGTTTCCTTTGTAAACCAGGATTCTTATTTGTGCTGTTATAGAAT
ATCAGCTCTGAACGTGTGGTAAAGATTTTTGTGTTTGAATATAGGAGAAATCAGTTTGCTGAAAAGTTAGTCTTAATTATCTATTGGCCA
CGATGAAACAGATTTCAACTGATAAAGAGCTGGAGAACTCCATGTACTTTGGAATCTCCTCCAAGATAGCCAGAGTTTAATACATCTTCA
TTCTCAACACTCTCCAAAGAACTTGACCTACCTTATGGGTTCCATATTTTTCTTCTTAAATGTGCATCAATCATGCCTTGCCCCCAACCT
TTAAATATATTCTTAGACCTGGTAAATGCACTCAGACTTGCGTCTTTAGGAATTTTTAACTTTCTTTCACTACATTGGCACTTAAATTTT
TTCTTTATAAAGCTTTTTGAAGGTCATAAACAAAGACCATAATTGATGATAGACCTAATACATTTCCTCTGTGTGTGTGTGTAACATTCC
AAATACTTTTTTTTTCTTTTCCACTGTTTGTAAGGTGCAACAATTTAATATTTTTAAGGGACTTTTTAAGAGTTCCTTAAGAACCAATTT
AAAATTACTTCAGTGCAATCCTACACAGTATCAACATTAGAATTTTGATATTAGTCTTATGTTATCTTCCATTCTATTTTTATCTGCTTT
TTGCTGCTAGTTTCAAACTGCCAGTATTTTTCCTTTTGCTTTTAAAATAGTTACAATATTTTTCATGATAGCCACAGTATTGCCACAGTT
TATTATAATAAAGGGTTTTTATTTGATTTAGCGCATTCAAAGCTTTTTTCTATCACTTTTGTGTTCAGAATATAACCTTTGTGTGCGTGT
ATGTTGTGTGTGTGCATGTGTGGCGTATATGTGTGTTACAGGTTAATGCCTTCTTGGAATTGTGTTAATGTTCTCTTGGTTTATTATGCC

>56300_56300_5_MYH11-MYLK_MYH11_chr16_15809021_ENST00000576790_MYLK_chr3_123383105_ENST00000360304_length(amino acids)=2517AA_BP=1880
MEIWDQQGTMAQKGQLSDDEKFLFVDKNFINSPVAQADWAAKRLVWVPSEKQGFEAASIKEEKGDEVVVELVENGKKVTVGKDDIQKMNP
PKFSKVEDMAELTCLNEASVLHNLRERYFSGLIYTYSGLFCVVVNPYKHLPIYSEKIVDMYKGKKRHEMPPHIYAIADTAYRSMLQDRED
QSILCTGESGAGKTENTKKVIQYLAVVASSHKGKKDTSITGELEKQLLQANPILEAFGNAKTVKNDNSSRFGKFIRINFDVTGYIVGANI
ETYLLEKSRAIRQARDERTFHIFYYMIAGAKEKMRSDLLLEGFNNYTFLSNGFVPIPAAQDDEMFQETVEAMAIMGFSEEEQLSILKVVS
SVLQLGNIVFKKERNTDQASMPDNTAAQKVCHLMGINVTDFTRSILTPRIKVGRDVVQKAQTKEQADFAVEALAKATYERLFRWILTRVN
KALDKTHRQGASFLGILDIAGFEIFEVNSFEQLCINYTNEKLQQLFNHTMFILEQEEYQREGIEWNFIDFGLDLQPCIELIERPNNPPGV
LALLDEECWFPKATDKSFVEKLCTEQGSHPKFQKPKQLKDKTEFSIIHYAGKVDYNASAWLTKNMDPLNDNVTSLLNASSDKFVADLWKD
VDRIVGLDQMAKMTESSLPSASKTKKGMFRTVGQLYKEQLGKLMTTLRNTTPNFVRCIIPNHEKRSGKLDAFLVLEQLRCNGVLEGIRIC
RQGFPNRIVFQEFRQRYEILAANAIPKGFMDGKQACILMIKALELDPNLYRIGQSKIFFRTGVLAHLEEERDLKITDVIMAFQAMCRGYL
ARKAFAKRQQQLTAMKVIQRNCAAYLKLRNWQWWRLFTKVKPLLQVTRQEEEMQAKEDELQKTKERQQKAENELKELEQKHSQLTEEKNL
LQEQLQAETELYAEAEEMRVRLAAKKQELEEILHEMEARLEEEEDRGQQLQAERKKMAQQMLDLEEQLEEEEAARQKLQLEKVTAEAKIK
KLEDEILVMDDQNNKLSKERKLLEERISDLTTNLAEEEEKAKNLTKLKNKHESMISELEVRLKKEEKSRQELEKLKRKLEGDASDFHEQI
ADLQAQIAELKMQLAKKEEELQAALARLDDEIAQKNNALKKIRELEGHISDLQEDLDSERAARNKAEKQKRDLGEELEALKTELEDTLDS
TATQQELRAKREQEVTVLKKALDEETRSHEAQVQEMRQKHAQAVEELTEQLEQFKRAKANLDKNKQTLEKENADLAGELRVLGQAKQEVE
HKKKKLEAQVQELQSKCSDGERARAELNDKVHKLQNEVESVTGMLNEAEGKAIKLAKDVASLSSQLQDTQELLQEETRQKLNVSTKLRQL
EEERNSLQDQLDEEMEAKQNLERHISTLNIQLSDSKKKLQDFASTVEALEEGKKRFQKEIENLTQQYEEKAAAYDKLEKTKNRLQQELDD
LVVDLDNQRQLVSNLEKKQRKFDQLLAEEKNISSKYADERDRAEAEAREKETKALSLARALEEALEAKEELERTNKMLKAEMEDLVSSKD
DVGKNVHELEKSKRALETQMEEMKTQLEELEDELQATEDAKLRLEVNMQALKGQFERDLQARDEQNEEKRRQLQRQLHEYETELEDERKQ
RALAAAAKKKLEGDLKDLELQADSAIKGREEAIKQLRKLQAQMKDFQRELEDARASRDEIFATAKENEKKAKSLEADLMQLQEDLAAAER
ARKQADLEKEELAEELASSLSGRNALQDEKRRLEARIAQLEEELEEEQGNMEAMSDRVRKATQQAEQLSNELATERSTAQKNESARQQLE
RQNKELRSKLHEMEGAVKSKFKSTIAALEAKIAQLEEQVEQEAREKQAATKSLKQKDKKLKEILLQVEDERKMAEQYKEQIQESEHMKVE
NSENGSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTVVDKPDPPAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSIEIWDSANKT
WKELATCRSTSFNVQDLLPDHEYKFRVRAINVYGTSEPSQESELTTVGEKPEEPKDEVEVSDDDEKEPEVDYRTVTINTEQKVSDFYDIE
ERLGSGKFGQVFRLVEKKTRKVWAGKFFKAYSAKEKENIRQEISIMNCLHHPKLVQCVDAFEEKANIVMVLEIVSGGELFERIIDEDFEL
TERECIKYMRQISEGVEYIHKQGIVHLDLKPENIMCVNKTGTRIKLIDFGLARRLENAGSLKVLFGTPEFVAPEVINYEPIGYATDMWSI
GVICYILVSGLSPFMGDNDNETLANVTSATWDFDDEAFDEISDDAKDFISNLLKKDMKNRLDCTQCLQHPWLMKDTKNMEAKKLSKDRMK
KYMARRKWQKTGNAVRAIGRLSSMAMISGLSGRKSSTGSPTSPLNAEKLESEEDVSQAFLEAVAEEKPHVKPYFSKTIRDLEVVEGSAAR

--------------------------------------------------------------
>56300_56300_6_MYH11-MYLK_MYH11_chr16_15809021_ENST00000576790_MYLK_chr3_123383105_ENST00000360772_length(transcript)=11540nt_BP=5723nt
GCAGGGAGATTTGGACGCTCCGGCCTGGGAGGTGCGTCAGATCCGAGCTCGCCATCCAGTTTCCTCTCCACTAGTCCCCCCAGTTGGAGA
TCTGGGACCAACAAGGCACCATGGCGCAGAAGGGCCAACTCAGTGACGATGAGAAGTTCCTCTTTGTGGACAAAAACTTCATCAACAGCC
CAGTGGCCCAGGCTGACTGGGCCGCCAAGAGACTCGTCTGGGTCCCCTCGGAGAAGCAGGGCTTCGAGGCAGCCAGCATTAAGGAGGAGA
AGGGGGATGAGGTGGTTGTGGAGCTGGTGGAGAATGGCAAGAAGGTCACGGTTGGGAAAGATGACATCCAGAAGATGAACCCACCCAAGT
TCTCCAAGGTGGAGGACATGGCGGAGCTGACGTGCCTCAACGAAGCCTCCGTGCTACACAACCTGAGGGAGCGGTACTTCTCAGGGCTAA
TATATACGTACTCTGGCCTCTTCTGCGTGGTGGTCAACCCCTATAAACACCTGCCCATCTACTCGGAGAAGATCGTCGACATGTACAAGG
GCAAGAAGAGGCACGAGATGCCGCCTCACATCTACGCCATCGCAGACACGGCCTACCGGAGCATGCTTCAAGATCGGGAGGACCAGTCCA
TTCTATGCACAGGCGAGTCTGGAGCCGGGAAAACCGAAAACACCAAGAAGGTCATTCAGTACCTGGCCGTGGTGGCCTCCTCCCACAAGG
GCAAGAAAGACACAAGTATCACGGGAGAGCTGGAAAAGCAGCTTCTACAAGCAAACCCGATTCTGGAGGCTTTCGGCAACGCCAAAACAG
TGAAGAACGACAACTCCTCACGATTCGGCAAATTCATCCGCATCAACTTCGACGTCACGGGTTACATCGTGGGAGCCAACATTGAGACCT
ATCTGCTAGAAAAATCACGGGCAATTCGCCAAGCCAGAGACGAGAGGACATTCCACATCTTTTACTACATGATTGCTGGAGCCAAGGAGA
AGATGAGAAGTGACTTGCTTTTGGAGGGCTTCAACAACTACACCTTCCTCTCCAATGGCTTTGTGCCCATCCCAGCAGCCCAGGATGATG
AGATGTTCCAGGAAACCGTGGAGGCCATGGCAATCATGGGTTTCAGCGAGGAGGAGCAGCTATCCATATTGAAGGTGGTATCATCGGTCC
TGCAGCTTGGAAATATCGTCTTCAAGAAGGAAAGAAACACAGACCAGGCGTCCATGCCAGATAACACAGCTGCTCAGAAAGTTTGCCACC
TCATGGGAATTAATGTGACAGATTTCACCAGATCCATCCTCACTCCTCGTATCAAGGTTGGGCGAGATGTGGTACAGAAAGCTCAGACAA
AAGAACAGGCTGACTTTGCTGTAGAGGCTTTGGCCAAGGCAACATATGAGCGCCTTTTCCGCTGGATACTCACCCGCGTGAACAAAGCCC
TGGACAAGACCCATCGGCAAGGGGCTTCCTTCCTGGGGATCCTGGATATAGCTGGATTTGAGATCTTTGAGGTGAACTCCTTCGAGCAGC
TGTGCATCAACTACACCAACGAGAAGCTGCAGCAGCTCTTCAACCACACCATGTTCATCCTGGAGCAGGAGGAGTACCAGCGCGAGGGCA
TCGAGTGGAACTTCATCGACTTTGGGCTGGACCTACAGCCCTGCATCGAGCTCATCGAGCGACCGAACAACCCTCCAGGTGTGCTGGCCC
TGCTGGACGAGGAATGCTGGTTCCCCAAAGCCACGGACAAGTCTTTCGTGGAGAAGCTGTGCACGGAGCAGGGCAGCCACCCCAAGTTCC
AGAAGCCCAAGCAGCTCAAGGACAAGACTGAGTTCTCCATCATCCATTATGCTGGGAAGGTGGACTATAATGCGAGTGCCTGGCTGACCA
AGAATATGGACCCGCTGAATGACAACGTGACTTCCCTGCTCAATGCCTCCTCCGACAAGTTTGTGGCCGACCTGTGGAAGGACGTGGACC
GCATCGTGGGCCTGGACCAGATGGCCAAGATGACGGAGAGCTCGCTGCCCAGCGCCTCCAAGACCAAGAAGGGCATGTTCCGCACAGTGG
GGCAGCTGTACAAGGAGCAGCTGGGCAAGCTGATGACCACGCTACGCAACACCACGCCCAACTTCGTGCGCTGCATCATCCCCAACCACG
AGAAGAGGTCCGGCAAGCTGGATGCGTTCCTGGTGCTGGAGCAGCTGCGGTGCAATGGGGTGCTGGAAGGCATTCGCATCTGCCGGCAGG
GCTTCCCCAACCGGATCGTCTTCCAGGAGTTCCGCCAACGCTACGAGATCCTGGCGGCGAATGCCATCCCCAAAGGCTTCATGGACGGGA
AGCAGGCCTGCATTCTCATGATCAAAGCCCTGGAACTTGACCCCAACTTATACAGGATAGGGCAGAGCAAAATCTTCTTCCGAACTGGCG
TCCTGGCCCACCTAGAGGAGGAGCGAGATTTGAAGATCACCGATGTCATCATGGCCTTCCAGGCGATGTGTCGTGGCTACTTGGCCAGAA
AGGCTTTTGCCAAGAGGCAGCAGCAGCTGACCGCCATGAAGGTGATTCAGAGGAACTGCGCCGCCTACCTCAAGCTGCGGAACTGGCAGT
GGTGGAGGCTTTTCACCAAAGTGAAGCCACTGCTGCAGGTGACACGGCAGGAGGAGGAGATGCAGGCCAAGGAGGATGAACTGCAGAAGA
CCAAGGAGCGGCAGCAGAAGGCAGAGAATGAGCTTAAGGAGCTGGAACAGAAGCACTCGCAGCTGACCGAGGAGAAGAACCTGCTACAGG
AACAGCTGCAGGCAGAGACAGAGCTGTATGCAGAGGCTGAGGAGATGCGGGTGCGGCTGGCGGCCAAGAAGCAGGAGCTGGAGGAGATAC
TGCATGAGATGGAGGCCCGCCTGGAGGAGGAGGAAGACAGGGGCCAGCAGCTACAGGCTGAAAGGAAGAAGATGGCCCAGCAGATGCTGG
ACCTTGAAGAACAGCTGGAGGAGGAGGAAGCTGCCAGGCAGAAGCTGCAACTTGAGAAGGTCACGGCTGAGGCCAAGATCAAGAAACTGG
AGGATGAGATCCTGGTCATGGATGATCAGAACAATAAACTATCAAAAGAACGAAAACTCCTTGAGGAGAGGATTAGTGACTTAACGACAA
ATCTTGCAGAAGAGGAAGAAAAGGCCAAGAATCTTACCAAGCTGAAAAACAAGCATGAATCTATGATTTCAGAACTGGAAGTGCGGCTAA
AGAAGGAAGAGAAGAGCCGACAGGAGCTGGAGAAGCTGAAACGGAAGCTGGAGGGTGATGCCAGCGACTTCCACGAGCAGATCGCTGACC
TCCAGGCGCAGATCGCAGAGCTCAAGATGCAGCTGGCCAAGAAGGAGGAGGAGCTGCAGGCGGCCCTGGCCAGGCTTGACGATGAAATCG
CTCAGAAGAACAATGCCCTGAAGAAGATCCGGGAGCTGGAGGGCCACATCTCAGACCTCCAGGAGGACCTGGACTCAGAGCGGGCCGCCA
GGAACAAGGCTGAAAAGCAGAAGCGAGACCTCGGCGAGGAGCTGGAGGCCCTAAAGACAGAGCTGGAAGACACACTGGACAGCACAGCCA
CTCAGCAGGAGCTCAGGGCCAAGAGGGAGCAGGAGGTGACGGTGCTGAAGAAGGCCCTGGATGAAGAGACGCGGTCCCATGAGGCTCAGG
TCCAGGAGATGAGGCAGAAACACGCACAGGCGGTGGAGGAGCTCACAGAGCAGCTTGAGCAGTTCAAGAGGGCCAAGGCGAACCTAGACA
AGAATAAGCAGACGCTGGAGAAAGAGAACGCAGACCTGGCCGGGGAGCTGCGGGTCCTGGGCCAGGCCAAGCAGGAGGTGGAACATAAGA
AGAAGAAGCTGGAGGCGCAGGTGCAGGAGCTGCAGTCCAAGTGCAGCGATGGGGAGCGGGCCCGGGCGGAGCTCAATGACAAAGTCCACA
AGCTGCAGAATGAAGTTGAGAGCGTCACAGGGATGCTTAACGAGGCCGAGGGGAAGGCCATTAAGCTGGCCAAGGACGTGGCGTCCCTCA
GTTCCCAGCTCCAGGACACCCAGGAGCTGCTTCAAGAAGAAACCCGGCAGAAGCTCAACGTGTCTACGAAGCTGCGCCAGCTGGAGGAGG
AGCGGAACAGCCTGCAAGACCAGCTGGACGAGGAGATGGAGGCCAAGCAGAACCTGGAGCGCCACATCTCCACTCTCAACATCCAGCTCT
CCGACTCGAAGAAGAAGCTGCAGGACTTTGCCAGCACCGTGGAAGCTCTGGAAGAGGGGAAGAAGAGGTTCCAGAAGGAGATCGAGAACC
TCACCCAGCAGTACGAGGAGAAGGCGGCCGCTTATGATAAACTGGAAAAGACCAAGAACAGGCTTCAGCAGGAGCTGGACGACCTGGTTG
TTGATTTGGACAACCAGCGGCAACTCGTGTCCAACCTGGAAAAGAAGCAGAGGAAATTTGATCAGTTGTTAGCCGAGGAGAAAAACATCT
CTTCCAAATACGCGGATGAGAGGGACAGAGCTGAGGCAGAAGCCAGGGAGAAGGAAACCAAGGCCCTGTCCCTGGCTCGGGCCCTTGAAG
AGGCCTTGGAAGCCAAAGAGGAACTCGAGCGGACCAACAAAATGCTCAAAGCCGAAATGGAAGACCTGGTCAGCTCCAAGGATGACGTGG
GCAAGAACGTCCATGAGCTGGAGAAGTCCAAGCGGGCCCTGGAGACCCAGATGGAGGAGATGAAGACGCAGCTGGAAGAGCTGGAGGACG
AGCTGCAAGCCACGGAGGACGCCAAACTGCGGCTGGAAGTCAACATGCAGGCGCTCAAGGGCCAGTTCGAAAGGGATCTCCAAGCCCGGG
ACGAGCAGAATGAGGAGAAGAGGAGGCAACTGCAGAGACAGCTTCACGAGTATGAGACGGAACTGGAAGACGAGCGAAAGCAACGTGCCC
TGGCAGCTGCAGCAAAGAAGAAGCTGGAAGGGGACCTGAAAGACCTGGAGCTTCAGGCCGACTCTGCCATCAAGGGGAGGGAGGAAGCCA
TCAAGCAGCTACGCAAACTGCAGGCTCAGATGAAGGACTTTCAAAGAGAGCTGGAAGATGCCCGTGCCTCCAGAGATGAGATCTTTGCCA
CAGCCAAAGAGAATGAGAAGAAAGCCAAGAGCTTGGAAGCAGACCTCATGCAGCTACAAGAGGACCTCGCCGCCGCTGAGAGGGCTCGCA
AACAAGCGGACCTCGAGAAGGAGGAACTGGCAGAGGAGCTGGCCAGTAGCCTGTCGGGAAGGAACGCACTCCAGGACGAGAAGCGCCGCC
TGGAGGCCCGGATCGCCCAGCTGGAGGAGGAGCTGGAGGAGGAGCAGGGCAACATGGAGGCCATGAGCGACCGGGTCCGCAAAGCCACAC
AGCAGGCCGAGCAGCTCAGCAACGAGCTGGCCACAGAGCGCAGCACGGCCCAGAAGAATGAGAGTGCCCGGCAGCAGCTCGAGCGGCAGA
ACAAGGAGCTCCGGAGCAAGCTCCACGAGATGGAGGGGGCCGTCAAGTCCAAGTTCAAGTCCACCATCGCGGCGCTGGAGGCCAAGATTG
CACAGCTGGAGGAGCAGGTCGAGCAGGAGGCCAGAGAGAAACAGGCGGCCACCAAGTCGCTGAAGCAGAAAGACAAGAAGCTGAAGGAAA
TCTTGCTGCAGGTGGAGGACGAGCGCAAGATGGCCGAGCAGTACAAGGAGCAGATCCAGGAAAGCGAGCACATGAAGGTGGAGAACAGCG
AGAATGGCAGCAAGCTCACCATCCTGGCCGCGCGCCAGGAGCACTGCGGCTGCTACACACTGCTGGTGGAGAACAAGCTGGGCAGCAGGC
AGGCCCAGGTCAACCTCACTGTCGTGGATAAGCCAGACCCCCCAGCTGGCACACCTTGTGCCTCTGACATTCGGAGCTCCTCACTGACCC
TGTCCTGGTATGGCTCCTCATATGATGGGGGCAGTGCTGTACAGTCCTACAGCATCGAGATCTGGGACTCAGCCAACAAGACGTGGAAGG
AACTAGCCACATGCCGCAGCACCTCTTTCAACGTCCAGGACCTGCTGCCTGACCACGAATATAAGTTCCGTGTACGTGCAATCAACGTGT
ATGGAACCAGTGAGCCAAGCCAGGAGTCTGAACTCACAACGGTAGGAGAGAAACCTGAAGAGCCGAAGGATGAAGTGGAGGTGTCAGATG
ATGATGAGAAGGAGCCCGAGGTTGATTACCGGACAGTGACAATCAATACTGAACAAAAAGTATCTGACTTCTACGACATTGAGGAGAGAT
TAGGATCTGGGAAATTTGGACAGGTCTTTCGACTTGTAGAAAAGAAAACTCGAAAAGTCTGGGCAGGGAAGTTCTTCAAGGCATATTCAG
CAAAAGAGAAAGAGAATATCCGGCAGGAGATTAGCATCATGAACTGCCTCCACCACCCTAAGCTGGTCCAGTGTGTGGATGCCTTTGAAG
AAAAGGCCAACATCGTCATGGTCCTGGAGATCGTGTCAGGAGGGGAGCTGTTTGAGCGCATCATTGACGAGGACTTTGAGCTGACGGAGC
GTGAGTGCATCAAGTACATGCGGCAGATCTCGGAGGGAGTGGAGTACATCCACAAGCAGGGCATCGTGCACCTGGACCTCAAGCCGGAGA
ACATCATGTGTGTCAACAAGACGGGCACCAGGATCAAGCTCATCGACTTTGGTCTGGCCAGGAGGCTGGAGAATGCGGGGTCTCTGAAGG
TCCTCTTTGGCACCCCAGAATTTGTGGCTCCTGAAGTGATCAACTATGAGCCCATCGGCTACGCCACAGACATGTGGAGCATCGGGGTCA
TCTGCTACATCCTAAACCGCCTGGACTGCACGCAGTGCCTTCAGCATCCATGGCTAATGAAAGATACCAAGAACATGGAGGCCAAGAAAC
TCTCCAAGGACCGGATGAAGAAGTACATGGCAAGAAGGAAATGGCAGAAAACGGGCAATGCTGTGAGAGCCATTGGAAGACTGTCCTCTA
TGGCAATGATCTCAGGGCTCAGTGGCAGGAAATCCTCAACAGGGTCACCAACCAGCCCGCTCAATGCAGAAAAACTAGAATCTGAAGAAG
ATGTGTCCCAAGCTTTCCTTGAGGCTGTTGCTGAGGAAAAGCCTCATGTAAAACCCTATTTCTCTAAGACCATTCGCGATTTAGAAGTTG
TGGAGGGAAGTGCTGCTAGATTTGACTGCAAGATTGAAGGATACCCAGACCCCGAGGTTGTCTGGTTCAAAGATGACCAGTCAATCAGGG
AGTCCCGCCACTTCCAGATAGACTACGATGAGGACGGGAACTGCTCTTTAATTATTAGTGATGTTTGCGGGGATGACGATGCCAAGTACA
CCTGCAAGGCTGTCAACAGTCTTGGAGAAGCCACCTGCACAGCAGAGCTCATTGTGGAAACGATGGAGGAAGGTGAAGGGGAAGGGGAAG
AGGAAGAAGAGTGAAACAAAGCCAGAGAAAAGCAGTTTCTAAGTCATATTAAAAGGACTATTTCTCTAAAACTCAAAAAAAAAAAAAAAA
CTCAAGATAGTAAAAGCACCTAGTGTGATAGATTATCGGTTAGGTCATTTGTGGGTTGATTCTTCAGAAACAGCAGTTGATACCTAGCAG
CGTTATTGATGGGCATTAATCTATGTTAGTTGGCACCTTAAGATACTAGTGCAGCTAGATTTCATTTAGGGAAATCACCAGTAACTTGAC
TGACCAATTGATTTTAGAGAGAAAGTAACCAAACCAAATATTTATCTGGGCAAAGTCATAAATTCTCCACTTGAATGCGCTCATGAAAAA
TAAGGCCAAAACAAGAGTTCTGGGCCACAGCTCAGCCCAGAGGGTTCCTGGGGATGGGAGGCCTCTCTCTCCCCACCCCCTGACTCTAGA
GAACTGGGTTTTCTCCCAGTACTCCAGCAATTCATTTCTGAAAGCAGTTGAGCCACTTTATTCCAAAGTACACTGCAGATGTTCAAACTC
TCCATTTCTCTTTCCCCTTCCACCTGCCAGTTTTGCTGACTCTCAACTTGTCATGAGTGTAAGCATTAAGGACATTATGCTTCTTCGATT
CTGAAGACAGGTCCCTGCTCATGGATGACTCTGGCTTCCTTAGGAAAATATTTTTCTTCCAAAATCAGTAGGAAATCTAAACTTATCCCC
TCTTTGCAGATGTCTAGCAGCTTCAGACATTTGGTTAAGAACCCATGGGAAAAAAAAAATCCTTGCTAATGTGGTTTCCTTTGTAAACCA
GGATTCTTATTTGTGCTGTTATAGAATATCAGCTCTGAACGTGTGGTAAAGATTTTTGTGTTTGAATATAGGAGAAATCAGTTTGCTGAA
AAGTTAGTCTTAATTATCTATTGGCCACGATGAAACAGATTTCAACTGATAAAGAGCTGGAGAACTCCATGTACTTTGGAATCTCCTCCA
AGATAGCCAGAGTTTAATACATCTTCATTCTCAACACTCTCCAAAGAACTTGACCTACCTTATGGGTTCCATATTTTTCTTCTTAAATGT
GCATCAATCATGCCTTGCCCCCAACCTTTAAATATATTCTTAGACCTGGTAAATGCACTCAGACTTGCGTCTTTAGGAATTTTTAACTTT
CTTTCACTACATTGGCACTTAAATTTTTTCTTTATAAAGCTTTTTGAAGGTCATAAACAAAGACCATAATTGATGATAGACCTAATACAT
TTCCTCTGTGTGTGTGTGTAACATTCCAAATACTTTTTTTTTCTTTTCCACTGTTTGTAAGGTGCAACAATTTAATATTTTTAAGGGACT
TTTTAAGAGTTCCTTAAGAACCAATTTAAAATTACTTCAGTGCAATCCTACACAGTATCAACATTAGAATTTTGATATTAGTCTTATGTT
ATCTTCCATTCTATTTTTATCTGCTTTTTGCTGCTAGTTTCAAACTGCCAGTATTTTTCCTTTTGCTTTTAAAATAGTTACAATATTTTT
CATGATAGCCACAGTATTGCCACAGTTTATTATAATAAAGGGTTTTTATTTGATTTAGCGCATTCAAAGCTTTTTTCTATCACTTTTGTG
TTCAGAATATAACCTTTGTGTGCGTGTATGTTGTGTGTGTGCATGTGTGGCGTATATGTGTGTTACAGGTTAATGCCTTCTTGGAATTGT
GTTAATGTTCTCTTGGTTTATTATGCCATCAGAATGGTAAATGAGAACACTACAACTGTAGTCAGCTCACAATTTTTAAATAAAGGATAC
CACAGTGCATGCTGTTTGTTCAATCTTTGCAGACTTCTCTTTCTTTCCATGCTACCAGTTGTAAAGGACACAGCTATATCCTGGAAATGA
AAAACAAACACTGTGGTGCCTAGATGTGAAGAACTGGCTTATGTGGTTGTGTTTTGCTATGGAACAGAATGATTTAGGAAGTTCTTGTTT
ATATAGGTAGCCGAATTTACACATTTAGTTCAAAATTTCTCTTGAGCATCAGCTTAGTACTATATCAATCATTCTAGAAGGATATCTTAT
AGAGCAGGTGTCCCCAACCCCCGGTAAGTAGCCTGTTAGGAACCAGGTCACACATAAGGAGGTTAGCAGTGGGCAAGTGAGCAAAGCATC
ATCTATATTTACAGCCGATCCCCATTGCTCGCATTACCGCCTGAGCTCTGCCTCCTGTCAGATCAGCGGCAGCATCAGGTTCTCTCAGGA
ACGAACTCTATTGTGAACTGCTCATGTGAGGGATCTAGGTTTCACGCTCCTTATGAGAATCTAACACCTGATGATCTGTCACTGTCTCCC
ATCACCCCTAGATGGGACAGTCTAGTTGCAGGAAAACAAGCTCAGGGCTTCCACTGATTCTACATTATGATGAGTTGTATACTTATTTTA
TATTATAATAAAATATATTATTACAATGTAATAATAATAGAAATAAAATGCACAATACATGTAATGTGCTTGAATAATCCCAAAACCACC
CCCTCTCCTGGTCCATGGAAAAACTGTCTTCCATGAAAGTGGTCCCTGGTGCCAAAAAGGTTAGGGACCACTGTTACAGAGTATCAGGTC
CTCAAGATGCTAAAATCTATATGACATTTTTAACATGTGACATTATCATCATCATCATCATCATCATCACTGATGATACTATTTACCAGG
GCATGGTTTGAATTGGTGACTTTGGTGCAGTTCATTATTGGCAGCCAAATGCTTTATCCATACCTTCATATTGAAGAATTTGTTATCAGG
AAACTACCAGTCCTGCTTTACAGGAAGTCTGTTATCAGATATCAGATGGCAAGTTCCCCATGTCTTCAGATGTTCAAACAATATTGTGGA
TGGTCTAGAAAGAGTTTAAGACATGCTGTTAAATGTAGGGCTAGATAATTCTCTGATTCTTTGATGTAGTCTGGAAAGAAACAATCCATT
GTCCAGTTAATAAATATTTAGTGTTTTCATTTTTAAGACACTCACAATCCACAAATGTCCCTAACAATTTATTATTTTTAAAGAAAATGA
CTTTTTATTCCTTGCTAGTGAAAAATGTACAATTTATATGCTGCACTGAGAAAAATAACAGATATACTTTCTTCCATTCATTTTCATCCC
AAACATATAAAAAATAATCCATTGATTGTTCCTTGCATTGCATATCTTATTAAAAGATATTTCCTACATGCAACTAATAAGACATGCTGA
CTGTTGTCAGCTCTAAATTTATGTAAAGATTTTTTATTTTTGTTAAAATGTTTGAAATTTGCTTTTTGCTCCACACCTCACCTGTTTTTG
ATAAATCTGTGCTAATAAGTACATAGGAGGTAATAAATAATTGAGTTGTGAGAAACCCAATTCTCCATTTTTCAAGAAAACACAAGTAGC
ACTACTCTCTTTATCCCTTGGGACTCCTTCCTGTAATTTGAAAGGGGGGGCTAATGTTGGTGGCAGTTGTTGCTAAGGATCTCTGCACAG
AGTTAGGGCTTCACTCTCGGCTTCCTGGTTAGATGGGGCCATGTGACTAGTCCTAGTCAGTGAGCTGTGACCAGAAGTGATGTATGTACC
CTCGGGACCAGAGCATTTATGTGCTGGTACAAGCCTCTCCATAATGACGGGCAACACATGAGATGGTGGCTGCTGCAGCCATCTGGGTCT
CTAGCCAACCCAAAATGGGGACATAACACAAGCAAGAAATAAACATTTGTTCTTATAAATCACCAAGATTTTGGGGTTCTCAGTGGCTGC
AACATAACCTAGACTATCCTGATACAGGCTTATCACCATGTTCTGGATGTGTGGTGACCAGGATGGTAGCCACTACTCACAAGTGGCTAT
TTAAATTTAAGTTACTTTAAAAAATAAAATAAAAAATTCAGTTCCTCAGTTGTATGAGTTACATTTCAAATGCTCGACAGTCACATGTAC
ATCACTTTTCAAATTATGTGAAATTAAAACTGAAAAGCTTGTGTGAAAGTCTAGAGAGTATGGTCTATAGTTTCATCAATTGTATTGGAT

>56300_56300_6_MYH11-MYLK_MYH11_chr16_15809021_ENST00000576790_MYLK_chr3_123383105_ENST00000360772_length(amino acids)=2466AA_BP=1880
MEIWDQQGTMAQKGQLSDDEKFLFVDKNFINSPVAQADWAAKRLVWVPSEKQGFEAASIKEEKGDEVVVELVENGKKVTVGKDDIQKMNP
PKFSKVEDMAELTCLNEASVLHNLRERYFSGLIYTYSGLFCVVVNPYKHLPIYSEKIVDMYKGKKRHEMPPHIYAIADTAYRSMLQDRED
QSILCTGESGAGKTENTKKVIQYLAVVASSHKGKKDTSITGELEKQLLQANPILEAFGNAKTVKNDNSSRFGKFIRINFDVTGYIVGANI
ETYLLEKSRAIRQARDERTFHIFYYMIAGAKEKMRSDLLLEGFNNYTFLSNGFVPIPAAQDDEMFQETVEAMAIMGFSEEEQLSILKVVS
SVLQLGNIVFKKERNTDQASMPDNTAAQKVCHLMGINVTDFTRSILTPRIKVGRDVVQKAQTKEQADFAVEALAKATYERLFRWILTRVN
KALDKTHRQGASFLGILDIAGFEIFEVNSFEQLCINYTNEKLQQLFNHTMFILEQEEYQREGIEWNFIDFGLDLQPCIELIERPNNPPGV
LALLDEECWFPKATDKSFVEKLCTEQGSHPKFQKPKQLKDKTEFSIIHYAGKVDYNASAWLTKNMDPLNDNVTSLLNASSDKFVADLWKD
VDRIVGLDQMAKMTESSLPSASKTKKGMFRTVGQLYKEQLGKLMTTLRNTTPNFVRCIIPNHEKRSGKLDAFLVLEQLRCNGVLEGIRIC
RQGFPNRIVFQEFRQRYEILAANAIPKGFMDGKQACILMIKALELDPNLYRIGQSKIFFRTGVLAHLEEERDLKITDVIMAFQAMCRGYL
ARKAFAKRQQQLTAMKVIQRNCAAYLKLRNWQWWRLFTKVKPLLQVTRQEEEMQAKEDELQKTKERQQKAENELKELEQKHSQLTEEKNL
LQEQLQAETELYAEAEEMRVRLAAKKQELEEILHEMEARLEEEEDRGQQLQAERKKMAQQMLDLEEQLEEEEAARQKLQLEKVTAEAKIK
KLEDEILVMDDQNNKLSKERKLLEERISDLTTNLAEEEEKAKNLTKLKNKHESMISELEVRLKKEEKSRQELEKLKRKLEGDASDFHEQI
ADLQAQIAELKMQLAKKEEELQAALARLDDEIAQKNNALKKIRELEGHISDLQEDLDSERAARNKAEKQKRDLGEELEALKTELEDTLDS
TATQQELRAKREQEVTVLKKALDEETRSHEAQVQEMRQKHAQAVEELTEQLEQFKRAKANLDKNKQTLEKENADLAGELRVLGQAKQEVE
HKKKKLEAQVQELQSKCSDGERARAELNDKVHKLQNEVESVTGMLNEAEGKAIKLAKDVASLSSQLQDTQELLQEETRQKLNVSTKLRQL
EEERNSLQDQLDEEMEAKQNLERHISTLNIQLSDSKKKLQDFASTVEALEEGKKRFQKEIENLTQQYEEKAAAYDKLEKTKNRLQQELDD
LVVDLDNQRQLVSNLEKKQRKFDQLLAEEKNISSKYADERDRAEAEAREKETKALSLARALEEALEAKEELERTNKMLKAEMEDLVSSKD
DVGKNVHELEKSKRALETQMEEMKTQLEELEDELQATEDAKLRLEVNMQALKGQFERDLQARDEQNEEKRRQLQRQLHEYETELEDERKQ
RALAAAAKKKLEGDLKDLELQADSAIKGREEAIKQLRKLQAQMKDFQRELEDARASRDEIFATAKENEKKAKSLEADLMQLQEDLAAAER
ARKQADLEKEELAEELASSLSGRNALQDEKRRLEARIAQLEEELEEEQGNMEAMSDRVRKATQQAEQLSNELATERSTAQKNESARQQLE
RQNKELRSKLHEMEGAVKSKFKSTIAALEAKIAQLEEQVEQEAREKQAATKSLKQKDKKLKEILLQVEDERKMAEQYKEQIQESEHMKVE
NSENGSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTVVDKPDPPAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSIEIWDSANKT
WKELATCRSTSFNVQDLLPDHEYKFRVRAINVYGTSEPSQESELTTVGEKPEEPKDEVEVSDDDEKEPEVDYRTVTINTEQKVSDFYDIE
ERLGSGKFGQVFRLVEKKTRKVWAGKFFKAYSAKEKENIRQEISIMNCLHHPKLVQCVDAFEEKANIVMVLEIVSGGELFERIIDEDFEL
TERECIKYMRQISEGVEYIHKQGIVHLDLKPENIMCVNKTGTRIKLIDFGLARRLENAGSLKVLFGTPEFVAPEVINYEPIGYATDMWSI
GVICYILNRLDCTQCLQHPWLMKDTKNMEAKKLSKDRMKKYMARRKWQKTGNAVRAIGRLSSMAMISGLSGRKSSTGSPTSPLNAEKLES
EEDVSQAFLEAVAEEKPHVKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDVCGDDDA

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Fusion Gene PPI Analysis for MYH11-MYLK


check button Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in

ChiPPI page.


check button Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160)
HgeneHgene's interactorsTgeneTgene's interactors


check button - Retained PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenStill interaction with


check button - Lost PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


check button - Retained PPIs, but lost function due to frame-shift fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


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Related Drugs for MYH11-MYLK


check button Drugs targeting genes involved in this fusion gene.
(DrugBank Version 5.1.8 2021-05-08)
PartnerGeneUniProtAccDrugBank IDDrug nameDrug activityDrug typeDrug status

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Related Diseases for MYH11-MYLK


check button Diseases associated with fusion partners.
(DisGeNet 4.0)
PartnerGeneDisease IDDisease name# pubmedsSource