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Center for Computational Systems Medicine
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Fusion Gene Summary

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Fusion Gene ORF analysis

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Fusion Genomic Features

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Fusion Protein Features

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Fusion Gene Sequence

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Fusion Gene PPI analysis

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Related Drugs

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Related Diseases

Fusion gene:MYL6-DDB1 (FusionGDB2 ID:56462)

Fusion Gene Summary for MYL6-DDB1

check button Fusion gene summary
Fusion gene informationFusion gene name: MYL6-DDB1
Fusion gene ID: 56462
HgeneTgene
Gene symbol

MYL6

DDB1

Gene ID

4637

1642

Gene namemyosin light chain 6damage specific DNA binding protein 1
SynonymsESMLC|LC17|LC17-GI|LC17-NM|LC17A|LC17B|MLC-3|MLC1SM|MLC3NM|MLC3SMDDBA|UV-DDB1|XAP1|XPCE|XPE|XPE-BF
Cytomap

12q13.2

11q12.2

Type of geneprotein-codingprotein-coding
Descriptionmyosin light polypeptide 617 kDa myosin light chainmyosin light chain A3myosin light chain alkali 3myosin, light chain 6, alkali, smooth muscle and non-musclemyosin, light polypeptide 6, alkali, smooth muscle and non-muscleDNA damage-binding protein 1DDB p127 subunitDNA damage-binding protein aHBV X-associated protein 1UV-DDB 1UV-damaged DNA-binding factorUV-damaged DNA-binding protein 1XAP-1XPE-binding factordamage-specific DNA binding protein 1, 127kDaxeroderma
Modification date2020031320200327
UniProtAcc.

DCAF8L2

Ensembl transtripts involved in fusion geneENST00000293422, ENST00000348108, 
ENST00000536128, ENST00000547408, 
ENST00000547649, ENST00000548293, 
ENST00000550697, ENST00000551589, 
ENST00000548400, ENST00000548580, 
ENST00000549017, ENST00000549566, 
ENST00000551954, 		ENST00000450997, 
ENST00000451943, ENST00000538470, 
ENST00000545930, ENST00000301764, 
Fusion gene scores* DoF score34 X 17 X 10=578010 X 12 X 5=600
# samples 3613
** MAII scorelog2(36/5780*10)=-4.00500068105837
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0		log2(13/600*10)=-2.20645087746743
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0
Context

PubMed: MYL6 [Title/Abstract] AND DDB1 [Title/Abstract] AND fusion [Title/Abstract]

Most frequent breakpointMYL6(56553514)-DDB1(61081441), # samples:1
Anticipated loss of major functional domain due to fusion event.
* DoF score (Degree of Frequency) = # partners X # break points X # cancer types
** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)

check button Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez
PartnerGeneGO IDGO termPubMed ID
TgeneDDB1

GO:0006511

ubiquitin-dependent protein catabolic process

11673459

TgeneDDB1

GO:0016567

protein ubiquitination

26431207|28886238

TgeneDDB1

GO:0035518

histone H2A monoubiquitination

22334663

TgeneDDB1

GO:0051702

interaction with symbiont

23137809

TgeneDDB1

GO:0070914

UV-damage excision repair

22334663


check buttonFusion gene breakpoints across MYL6 (5'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check buttonFusion gene breakpoints across DDB1 (3'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check button Fusion gene information from two resources (ChiTars 5.0 and ChimerDB 4.0)
* All genome coordinats were lifted-over on hg19.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
SourceDiseaseSampleHgeneHchrHbpHstrandTgeneTchrTbpTstrand
ChimerDB4STADTCGA-BR-8058-01AMYL6chr12

56553514

+DDB1chr11

61081441

-


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Fusion Gene ORF analysis for MYL6-DDB1

check button Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
ORFHenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrand
5CDS-intronENST00000293422ENST00000450997MYL6chr12

56553514

+DDB1chr11

61081441

-
5CDS-intronENST00000293422ENST00000451943MYL6chr12

56553514

+DDB1chr11

61081441

-
5CDS-intronENST00000293422ENST00000538470MYL6chr12

56553514

+DDB1chr11

61081441

-
5CDS-intronENST00000293422ENST00000545930MYL6chr12

56553514

+DDB1chr11

61081441

-
5CDS-intronENST00000348108ENST00000450997MYL6chr12

56553514

+DDB1chr11

61081441

-
5CDS-intronENST00000348108ENST00000451943MYL6chr12

56553514

+DDB1chr11

61081441

-
5CDS-intronENST00000348108ENST00000538470MYL6chr12

56553514

+DDB1chr11

61081441

-
5CDS-intronENST00000348108ENST00000545930MYL6chr12

56553514

+DDB1chr11

61081441

-
5CDS-intronENST00000536128ENST00000450997MYL6chr12

56553514

+DDB1chr11

61081441

-
5CDS-intronENST00000536128ENST00000451943MYL6chr12

56553514

+DDB1chr11

61081441

-
5CDS-intronENST00000536128ENST00000538470MYL6chr12

56553514

+DDB1chr11

61081441

-
5CDS-intronENST00000536128ENST00000545930MYL6chr12

56553514

+DDB1chr11

61081441

-
5CDS-intronENST00000547408ENST00000450997MYL6chr12

56553514

+DDB1chr11

61081441

-
5CDS-intronENST00000547408ENST00000451943MYL6chr12

56553514

+DDB1chr11

61081441

-
5CDS-intronENST00000547408ENST00000538470MYL6chr12

56553514

+DDB1chr11

61081441

-
5CDS-intronENST00000547408ENST00000545930MYL6chr12

56553514

+DDB1chr11

61081441

-
5CDS-intronENST00000547649ENST00000450997MYL6chr12

56553514

+DDB1chr11

61081441

-
5CDS-intronENST00000547649ENST00000451943MYL6chr12

56553514

+DDB1chr11

61081441

-
5CDS-intronENST00000547649ENST00000538470MYL6chr12

56553514

+DDB1chr11

61081441

-
5CDS-intronENST00000547649ENST00000545930MYL6chr12

56553514

+DDB1chr11

61081441

-
5CDS-intronENST00000548293ENST00000450997MYL6chr12

56553514

+DDB1chr11

61081441

-
5CDS-intronENST00000548293ENST00000451943MYL6chr12

56553514

+DDB1chr11

61081441

-
5CDS-intronENST00000548293ENST00000538470MYL6chr12

56553514

+DDB1chr11

61081441

-
5CDS-intronENST00000548293ENST00000545930MYL6chr12

56553514

+DDB1chr11

61081441

-
5CDS-intronENST00000550697ENST00000450997MYL6chr12

56553514

+DDB1chr11

61081441

-
5CDS-intronENST00000550697ENST00000451943MYL6chr12

56553514

+DDB1chr11

61081441

-
5CDS-intronENST00000550697ENST00000538470MYL6chr12

56553514

+DDB1chr11

61081441

-
5CDS-intronENST00000550697ENST00000545930MYL6chr12

56553514

+DDB1chr11

61081441

-
5CDS-intronENST00000551589ENST00000450997MYL6chr12

56553514

+DDB1chr11

61081441

-
5CDS-intronENST00000551589ENST00000451943MYL6chr12

56553514

+DDB1chr11

61081441

-
5CDS-intronENST00000551589ENST00000538470MYL6chr12

56553514

+DDB1chr11

61081441

-
5CDS-intronENST00000551589ENST00000545930MYL6chr12

56553514

+DDB1chr11

61081441

-
In-frameENST00000293422ENST00000301764MYL6chr12

56553514

+DDB1chr11

61081441

-
In-frameENST00000348108ENST00000301764MYL6chr12

56553514

+DDB1chr11

61081441

-
In-frameENST00000536128ENST00000301764MYL6chr12

56553514

+DDB1chr11

61081441

-
In-frameENST00000547408ENST00000301764MYL6chr12

56553514

+DDB1chr11

61081441

-
In-frameENST00000547649ENST00000301764MYL6chr12

56553514

+DDB1chr11

61081441

-
In-frameENST00000548293ENST00000301764MYL6chr12

56553514

+DDB1chr11

61081441

-
In-frameENST00000550697ENST00000301764MYL6chr12

56553514

+DDB1chr11

61081441

-
In-frameENST00000551589ENST00000301764MYL6chr12

56553514

+DDB1chr11

61081441

-
intron-3CDSENST00000548400ENST00000301764MYL6chr12

56553514

+DDB1chr11

61081441

-
intron-3CDSENST00000548580ENST00000301764MYL6chr12

56553514

+DDB1chr11

61081441

-
intron-3CDSENST00000549017ENST00000301764MYL6chr12

56553514

+DDB1chr11

61081441

-
intron-3CDSENST00000549566ENST00000301764MYL6chr12

56553514

+DDB1chr11

61081441

-
intron-3CDSENST00000551954ENST00000301764MYL6chr12

56553514

+DDB1chr11

61081441

-
intron-intronENST00000548400ENST00000450997MYL6chr12

56553514

+DDB1chr11

61081441

-
intron-intronENST00000548400ENST00000451943MYL6chr12

56553514

+DDB1chr11

61081441

-
intron-intronENST00000548400ENST00000538470MYL6chr12

56553514

+DDB1chr11

61081441

-
intron-intronENST00000548400ENST00000545930MYL6chr12

56553514

+DDB1chr11

61081441

-
intron-intronENST00000548580ENST00000450997MYL6chr12

56553514

+DDB1chr11

61081441

-
intron-intronENST00000548580ENST00000451943MYL6chr12

56553514

+DDB1chr11

61081441

-
intron-intronENST00000548580ENST00000538470MYL6chr12

56553514

+DDB1chr11

61081441

-
intron-intronENST00000548580ENST00000545930MYL6chr12

56553514

+DDB1chr11

61081441

-
intron-intronENST00000549017ENST00000450997MYL6chr12

56553514

+DDB1chr11

61081441

-
intron-intronENST00000549017ENST00000451943MYL6chr12

56553514

+DDB1chr11

61081441

-
intron-intronENST00000549017ENST00000538470MYL6chr12

56553514

+DDB1chr11

61081441

-
intron-intronENST00000549017ENST00000545930MYL6chr12

56553514

+DDB1chr11

61081441

-
intron-intronENST00000549566ENST00000450997MYL6chr12

56553514

+DDB1chr11

61081441

-
intron-intronENST00000549566ENST00000451943MYL6chr12

56553514

+DDB1chr11

61081441

-
intron-intronENST00000549566ENST00000538470MYL6chr12

56553514

+DDB1chr11

61081441

-
intron-intronENST00000549566ENST00000545930MYL6chr12

56553514

+DDB1chr11

61081441

-
intron-intronENST00000551954ENST00000450997MYL6chr12

56553514

+DDB1chr11

61081441

-
intron-intronENST00000551954ENST00000451943MYL6chr12

56553514

+DDB1chr11

61081441

-
intron-intronENST00000551954ENST00000538470MYL6chr12

56553514

+DDB1chr11

61081441

-
intron-intronENST00000551954ENST00000545930MYL6chr12

56553514

+DDB1chr11

61081441

-

check buttonORFfinder result based on the fusion transcript sequence of in-frame fusion genes.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandSeq length
(transcript)		BP loci
(transcript)		Predicted start
(transcript)		Predicted stop
(transcript)		Seq length
(amino acids)
ENST00000550697MYL6chr1256553514+ENST00000301764DDB1chr1161081441-27714162412085614
ENST00000293422MYL6chr1256553514+ENST00000301764DDB1chr1161081441-2579224461893615
ENST00000348108MYL6chr1256553514+ENST00000301764DDB1chr1161081441-2579224461893615
ENST00000536128MYL6chr1256553514+ENST00000301764DDB1chr1161081441-2849494402163707
ENST00000547649MYL6chr1256553514+ENST00000301764DDB1chr1161081441-2570215401884614
ENST00000547408MYL6chr1256553514+ENST00000301764DDB1chr1161081441-2564209341878614
ENST00000551589MYL6chr1256553514+ENST00000301764DDB1chr1161081441-2563208331877614
ENST00000548293MYL6chr1256553514+ENST00000301764DDB1chr1161081441-253618161850614

check buttonDeepORF prediction of the coding potential based on the fusion transcript sequence of in-frame fusion genes. DeepORF is a coding potential classifier based on convolutional neural network by comparing the real Ribo-seq data. If the no-coding score < 0.5 and coding score > 0.5, then the in-frame fusion transcript is predicted as being likely translated.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandNo-coding scoreCoding score
ENST00000550697ENST00000301764MYL6chr1256553514+DDB1chr1161081441-0.003347590.9966524
ENST00000293422ENST00000301764MYL6chr1256553514+DDB1chr1161081441-0.0034839210.9965161
ENST00000348108ENST00000301764MYL6chr1256553514+DDB1chr1161081441-0.0034839210.9965161
ENST00000536128ENST00000301764MYL6chr1256553514+DDB1chr1161081441-0.0010038960.9989961
ENST00000547649ENST00000301764MYL6chr1256553514+DDB1chr1161081441-0.0036011350.9963988
ENST00000547408ENST00000301764MYL6chr1256553514+DDB1chr1161081441-0.0036693030.9963307
ENST00000551589ENST00000301764MYL6chr1256553514+DDB1chr1161081441-0.0035804710.99641955
ENST00000548293ENST00000301764MYL6chr1256553514+DDB1chr1161081441-0.0035845490.9964154

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Fusion Genomic Features for MYL6-DDB1


check buttonFusionAI prediction of the potential fusion gene breakpoint based on the pre-mature RNA sequence context (+/- 5kb of individual partner genes, total 20kb length sequence). FusionAI is a fusion gene breakpoint classifier based on convolutional neural network by comparing the fusion positive and negative sequence context of ~ 20K fusion gene data. From here, we can have the relative potentency of the 20K genomic sequence how individual sequnce will be likely used as the gene fusion breakpoints.
HgeneHchrHbpHstrandTgeneTchrTbpTstrand1-pp (fusion gene breakpoint)

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions. We integrated a total of 44 different types of human genomic feature loci information across five big categories including virus integration sites, repeats, structural variants, chromatin states, and gene expression regulation. More details are in help page.
genomic feature

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions that are ovelapped with the top 1% feature importance score regions. More details are in help page.

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Fusion Protein Features for MYL6-DDB1


check button Four levels of functional features of fusion genes
Go to FGviewer search page for the most frequent breakpoint (https://ccsmweb.uth.edu/FGviewer/chr12:56553514/chr11:61081441)
- FGviewer provides the online visualization of the retention search of the protein functional features across DNA, RNA, protein, and pathological levels.
- How to search
1. Put your fusion gene symbol.
2. Press the tab key until there will be shown the breakpoint information filled.
4. Go down and press 'Search' tab twice.
4. Go down to have the hyperlink of the search result.
5. Click the hyperlink.
6. See the FGviewer result for your fusion gene.
FGviewer

check buttonMain function of each fusion partner protein. (from UniProt)
HgeneTgene
.DDB1

DCAF8L2

FUNCTION: Transcriptional activator which is required for calcium-dependent dendritic growth and branching in cortical neurons. Recruits CREB-binding protein (CREBBP) to nuclear bodies. Component of the CREST-BRG1 complex, a multiprotein complex that regulates promoter activation by orchestrating a calcium-dependent release of a repressor complex and a recruitment of an activator complex. In resting neurons, transcription of the c-FOS promoter is inhibited by BRG1-dependent recruitment of a phospho-RB1-HDAC1 repressor complex. Upon calcium influx, RB1 is dephosphorylated by calcineurin, which leads to release of the repressor complex. At the same time, there is increased recruitment of CREBBP to the promoter by a CREST-dependent mechanism, which leads to transcriptional activation. The CREST-BRG1 complex also binds to the NR2B promoter, and activity-dependent induction of NR2B expression involves a release of HDAC1 and recruitment of CREBBP (By similarity). {ECO:0000250}.631

check buttonRetention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at

download page


* Minus value of BPloci means that the break pointn is located before the CDS.
- In-frame and retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneMYL6chr12:56553514chr11:61081441ENST00000547649+367_4258152.0DomainEF-hand 1
HgeneMYL6chr12:56553514chr11:61081441ENST00000548293+367_4258152.0DomainEF-hand 1
HgeneMYL6chr12:56553514chr11:61081441ENST00000550697+377_4258133.33333333333334DomainEF-hand 1
TgeneDDB1chr12:56553514chr11:61081441ENST000003017641327709_10435841141.0RegionNote=WD repeat beta-propeller C

- In-frame and not-retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneMYL6chr12:56553514chr11:61081441ENST00000547649+36119_15158152.0DomainEF-hand 3
HgeneMYL6chr12:56553514chr11:61081441ENST00000547649+3684_11958152.0DomainEF-hand 2
HgeneMYL6chr12:56553514chr11:61081441ENST00000548293+36119_15158152.0DomainEF-hand 3
HgeneMYL6chr12:56553514chr11:61081441ENST00000548293+3684_11958152.0DomainEF-hand 2
HgeneMYL6chr12:56553514chr11:61081441ENST00000550697+37119_15158133.33333333333334DomainEF-hand 3
HgeneMYL6chr12:56553514chr11:61081441ENST00000550697+3784_11958133.33333333333334DomainEF-hand 2
TgeneDDB1chr12:56553514chr11:61081441ENST00000301764132713_3565841141.0RegionNote=WD repeat beta-propeller A


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Fusion Gene Sequence for MYL6-DDB1


check button For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. To have fusion amino acid sequence, we ran ORFfinder and chose the longest ORF among the all predicted ones.
>56462_56462_1_MYL6-DDB1_MYL6_chr12_56553514_ENST00000293422_DDB1_chr11_61081441_ENST00000301764_length(transcript)=2579nt_BP=224nt
GGAGCCATTACTGCAGGAAAAGGTCCCGGAGAGCTGAGCAGTCAAGATGCAGTGTGACTTCACCGAAGACCAGACCGCAGAGTTCAAGGA
GGCCTTCCAGCTGTTTGACCGAACAGGTGATGGCAAGATCCTGTACAGCCAGTGTGGGGATGTGATGAGGGCCCTGGGCCAGAACCCTAC
CAACGCCGAGGTGCTCAAGGTCCTGGGGAACCCCAAGAGTGATGAGATCATTCCTCGCTCCATCCTGATGACCACCTTTGAGAGTAGCCA
TTACCTCCTTTGTGCCTTGGGAGATGGAGCGCTTTTCTACTTTGGGCTCAACATTGAGACAGGTCTGTTGAGCGACCGTAAGAAGGTGAC
TTTGGGCACCCAGCCCACCGTATTGAGGACTTTTCGTTCTCTTTCTACCACCAACGTCTTTGCTTGTTCTGACCGCCCCACTGTCATCTA
TAGCAGCAACCACAAATTGGTCTTCTCAAATGTCAACCTCAAGGAAGTGAACTACATGTGTCCCCTCAATTCAGATGGCTATCCTGACAG
CCTGGCGCTGGCCAACAATAGCACCCTCACCATTGGCACCATCGATGAGATCCAGAAGCTGCACATTCGCACAGTTCCCCTCTATGAGTC
TCCAAGGAAGATCTGCTACCAGGAAGTGTCCCAGTGTTTCGGGGTCCTCTCCAGCCGCATTGAAGTCCAAGACACGAGTGGGGGCACGAC
AGCCTTGAGGCCCAGCGCTAGCACCCAGGCTCTGTCCAGCAGTGTAAGCTCCAGCAAGCTGTTCTCCAGCAGCACTGCTCCTCATGAGAC
CTCCTTTGGAGAAGAGGTGGAGGTGCACAACCTACTTATCATTGACCAACACACCTTTGAAGTGCTTCATGCCCACCAGTTTCTGCAGAA
TGAATATGCCCTCAGTCTGGTTTCCTGCAAGCTGGGCAAAGACCCCAACACTTACTTCATTGTGGGCACAGCAATGGTGTATCCTGAAGA
GGCAGAGCCCAAGCAGGGTCGCATTGTGGTCTTTCAGTATTCGGATGGAAAACTACAGACTGTGGCTGAAAAGGAAGTGAAAGGGGCCGT
GTACTCTATGGTGGAATTTAACGGGAAGCTGTTAGCCAGCATCAATAGCACGGTGCGGCTCTATGAGTGGACAACAGAGAAGGAGCTGCG
CACTGAGTGCAACCACTACAACAACATCATGGCCCTCTACCTGAAGACCAAGGGCGACTTCATCCTGGTGGGCGACCTTATGCGCTCAGT
GCTGCTGCTTGCCTACAAGCCCATGGAAGGAAACTTTGAAGAGATTGCTCGAGACTTTAATCCCAACTGGATGAGTGCTGTGGAAATCTT
GGATGATGACAATTTTCTGGGGGCTGAAAATGCCTTTAACTTGTTTGTGTGTCAAAAGGATAGCGCTGCCACCACTGACGAGGAGCGGCA
GCACCTCCAGGAGGTTGGTCTTTTCCACCTGGGCGAGTTTGTCAATGTCTTTTGCCACGGCTCTCTGGTAATGCAGAATCTGGGTGAGAC
TTCCACCCCCACACAAGGCTCGGTGCTCTTCGGCACGGTCAACGGCATGATAGGGCTGGTGACCTCACTGTCAGAGAGCTGGTACAACCT
CCTGCTGGACATGCAGAATCGACTCAATAAAGTCATCAAAAGTGTGGGGAAGATCGAGCACTCCTTCTGGAGATCCTTTCACACCGAGCG
GAAGACAGAACCAGCCACAGGTTTCATCGACGGTGACTTGATTGAGAGTTTCCTGGATATTAGCCGCCCCAAGATGCAGGAGGTGGTGGC
AAACCTACAGTATGACGATGGCAGCGGTATGAAGCGAGAGGCCACTGCAGACGACCTCATCAAGGTTGTGGAGGAGCTAACTCGGATCCA
TTAGCCAAGGGCAGGGGGCCCCTTTGCTGACCCTCCCCAAAGGCTTTGCCCTGCTGCCCTCCCCCTCCTCTCCACCATCGTCTTCTTGGC
CATGGGAGGCCTTTCCCTAAGCCAGCTGCCCCCAGAGCCACAGTTCCCCTATGTGGAAGTGGGGCGGGCTTCATAGAGACTTGGGAATGA
GCTGAAGGTGAAACATTTTCTCCCTGGATTTTTACCAGTCTCACATGATTCCAGCCATCACCTTAGACCACCAAGCCTTGATTGGTGTTG
CCAGTTGTCCTCCTTCCGGGGAAGGATTTTGCAGTTCTTTGGCTGAAAGGAAGCTGTGCGTGTGTGTGTGTGTATGTGTGTGTGTGTATG
TGTATCTCACACTCATGCATTGTCCTCTTTTTATTTAGATTGGCAGTGTAGGGAGTTGTGGGTAGTGGGGAAGAGGGTTAGGAGGGTTTC
ATTGTCTGTGAAGTGAGACCTTCCTTTTACTTTTCTTCTATTGCCTCTGAGAGCATCAGGCCTAGAGGCCTGACTGCCAAGCCATGGGTA
GCCTGGGTGTAAAACCTGGAGATGGTGGATGATCCCCACGCCACAGCCCTTTTGTCTCTGCAAACTGCCTTCTTCGGAAAGAAGAAGGTG

>56462_56462_1_MYL6-DDB1_MYL6_chr12_56553514_ENST00000293422_DDB1_chr11_61081441_ENST00000301764_length(amino acids)=615AA_BP=59
MQCDFTEDQTAEFKEAFQLFDRTGDGKILYSQCGDVMRALGQNPTNAEVLKVLGNPKSDEIIPRSILMTTFESSHYLLCALGDGALFYFG
LNIETGLLSDRKKVTLGTQPTVLRTFRSLSTTNVFACSDRPTVIYSSNHKLVFSNVNLKEVNYMCPLNSDGYPDSLALANNSTLTIGTID
EIQKLHIRTVPLYESPRKICYQEVSQCFGVLSSRIEVQDTSGGTTALRPSASTQALSSSVSSSKLFSSSTAPHETSFGEEVEVHNLLIID
QHTFEVLHAHQFLQNEYALSLVSCKLGKDPNTYFIVGTAMVYPEEAEPKQGRIVVFQYSDGKLQTVAEKEVKGAVYSMVEFNGKLLASIN
STVRLYEWTTEKELRTECNHYNNIMALYLKTKGDFILVGDLMRSVLLLAYKPMEGNFEEIARDFNPNWMSAVEILDDDNFLGAENAFNLF
VCQKDSAATTDEERQHLQEVGLFHLGEFVNVFCHGSLVMQNLGETSTPTQGSVLFGTVNGMIGLVTSLSESWYNLLLDMQNRLNKVIKSV

--------------------------------------------------------------
>56462_56462_2_MYL6-DDB1_MYL6_chr12_56553514_ENST00000348108_DDB1_chr11_61081441_ENST00000301764_length(transcript)=2579nt_BP=224nt
GGAGCCATTACTGCAGGAAAAGGTCCCGGAGAGCTGAGCAGTCAAGATGCAGTGTGACTTCACCGAAGACCAGACCGCAGAGTTCAAGGA
GGCCTTCCAGCTGTTTGACCGAACAGGTGATGGCAAGATCCTGTACAGCCAGTGTGGGGATGTGATGAGGGCCCTGGGCCAGAACCCTAC
CAACGCCGAGGTGCTCAAGGTCCTGGGGAACCCCAAGAGTGATGAGATCATTCCTCGCTCCATCCTGATGACCACCTTTGAGAGTAGCCA
TTACCTCCTTTGTGCCTTGGGAGATGGAGCGCTTTTCTACTTTGGGCTCAACATTGAGACAGGTCTGTTGAGCGACCGTAAGAAGGTGAC
TTTGGGCACCCAGCCCACCGTATTGAGGACTTTTCGTTCTCTTTCTACCACCAACGTCTTTGCTTGTTCTGACCGCCCCACTGTCATCTA
TAGCAGCAACCACAAATTGGTCTTCTCAAATGTCAACCTCAAGGAAGTGAACTACATGTGTCCCCTCAATTCAGATGGCTATCCTGACAG
CCTGGCGCTGGCCAACAATAGCACCCTCACCATTGGCACCATCGATGAGATCCAGAAGCTGCACATTCGCACAGTTCCCCTCTATGAGTC
TCCAAGGAAGATCTGCTACCAGGAAGTGTCCCAGTGTTTCGGGGTCCTCTCCAGCCGCATTGAAGTCCAAGACACGAGTGGGGGCACGAC
AGCCTTGAGGCCCAGCGCTAGCACCCAGGCTCTGTCCAGCAGTGTAAGCTCCAGCAAGCTGTTCTCCAGCAGCACTGCTCCTCATGAGAC
CTCCTTTGGAGAAGAGGTGGAGGTGCACAACCTACTTATCATTGACCAACACACCTTTGAAGTGCTTCATGCCCACCAGTTTCTGCAGAA
TGAATATGCCCTCAGTCTGGTTTCCTGCAAGCTGGGCAAAGACCCCAACACTTACTTCATTGTGGGCACAGCAATGGTGTATCCTGAAGA
GGCAGAGCCCAAGCAGGGTCGCATTGTGGTCTTTCAGTATTCGGATGGAAAACTACAGACTGTGGCTGAAAAGGAAGTGAAAGGGGCCGT
GTACTCTATGGTGGAATTTAACGGGAAGCTGTTAGCCAGCATCAATAGCACGGTGCGGCTCTATGAGTGGACAACAGAGAAGGAGCTGCG
CACTGAGTGCAACCACTACAACAACATCATGGCCCTCTACCTGAAGACCAAGGGCGACTTCATCCTGGTGGGCGACCTTATGCGCTCAGT
GCTGCTGCTTGCCTACAAGCCCATGGAAGGAAACTTTGAAGAGATTGCTCGAGACTTTAATCCCAACTGGATGAGTGCTGTGGAAATCTT
GGATGATGACAATTTTCTGGGGGCTGAAAATGCCTTTAACTTGTTTGTGTGTCAAAAGGATAGCGCTGCCACCACTGACGAGGAGCGGCA
GCACCTCCAGGAGGTTGGTCTTTTCCACCTGGGCGAGTTTGTCAATGTCTTTTGCCACGGCTCTCTGGTAATGCAGAATCTGGGTGAGAC
TTCCACCCCCACACAAGGCTCGGTGCTCTTCGGCACGGTCAACGGCATGATAGGGCTGGTGACCTCACTGTCAGAGAGCTGGTACAACCT
CCTGCTGGACATGCAGAATCGACTCAATAAAGTCATCAAAAGTGTGGGGAAGATCGAGCACTCCTTCTGGAGATCCTTTCACACCGAGCG
GAAGACAGAACCAGCCACAGGTTTCATCGACGGTGACTTGATTGAGAGTTTCCTGGATATTAGCCGCCCCAAGATGCAGGAGGTGGTGGC
AAACCTACAGTATGACGATGGCAGCGGTATGAAGCGAGAGGCCACTGCAGACGACCTCATCAAGGTTGTGGAGGAGCTAACTCGGATCCA
TTAGCCAAGGGCAGGGGGCCCCTTTGCTGACCCTCCCCAAAGGCTTTGCCCTGCTGCCCTCCCCCTCCTCTCCACCATCGTCTTCTTGGC
CATGGGAGGCCTTTCCCTAAGCCAGCTGCCCCCAGAGCCACAGTTCCCCTATGTGGAAGTGGGGCGGGCTTCATAGAGACTTGGGAATGA
GCTGAAGGTGAAACATTTTCTCCCTGGATTTTTACCAGTCTCACATGATTCCAGCCATCACCTTAGACCACCAAGCCTTGATTGGTGTTG
CCAGTTGTCCTCCTTCCGGGGAAGGATTTTGCAGTTCTTTGGCTGAAAGGAAGCTGTGCGTGTGTGTGTGTGTATGTGTGTGTGTGTATG
TGTATCTCACACTCATGCATTGTCCTCTTTTTATTTAGATTGGCAGTGTAGGGAGTTGTGGGTAGTGGGGAAGAGGGTTAGGAGGGTTTC
ATTGTCTGTGAAGTGAGACCTTCCTTTTACTTTTCTTCTATTGCCTCTGAGAGCATCAGGCCTAGAGGCCTGACTGCCAAGCCATGGGTA
GCCTGGGTGTAAAACCTGGAGATGGTGGATGATCCCCACGCCACAGCCCTTTTGTCTCTGCAAACTGCCTTCTTCGGAAAGAAGAAGGTG

>56462_56462_2_MYL6-DDB1_MYL6_chr12_56553514_ENST00000348108_DDB1_chr11_61081441_ENST00000301764_length(amino acids)=615AA_BP=59
MQCDFTEDQTAEFKEAFQLFDRTGDGKILYSQCGDVMRALGQNPTNAEVLKVLGNPKSDEIIPRSILMTTFESSHYLLCALGDGALFYFG
LNIETGLLSDRKKVTLGTQPTVLRTFRSLSTTNVFACSDRPTVIYSSNHKLVFSNVNLKEVNYMCPLNSDGYPDSLALANNSTLTIGTID
EIQKLHIRTVPLYESPRKICYQEVSQCFGVLSSRIEVQDTSGGTTALRPSASTQALSSSVSSSKLFSSSTAPHETSFGEEVEVHNLLIID
QHTFEVLHAHQFLQNEYALSLVSCKLGKDPNTYFIVGTAMVYPEEAEPKQGRIVVFQYSDGKLQTVAEKEVKGAVYSMVEFNGKLLASIN
STVRLYEWTTEKELRTECNHYNNIMALYLKTKGDFILVGDLMRSVLLLAYKPMEGNFEEIARDFNPNWMSAVEILDDDNFLGAENAFNLF
VCQKDSAATTDEERQHLQEVGLFHLGEFVNVFCHGSLVMQNLGETSTPTQGSVLFGTVNGMIGLVTSLSESWYNLLLDMQNRLNKVIKSV

--------------------------------------------------------------
>56462_56462_3_MYL6-DDB1_MYL6_chr12_56553514_ENST00000536128_DDB1_chr11_61081441_ENST00000301764_length(transcript)=2849nt_BP=494nt
ATTACTGCAGGAAAAGGTCCCGGAGAGCTGAGCAGTCAAGATGGTGGGGCCCAGGTCTTGGGAGACGGGCAGGATTGGGGACGAGAGGCA
GGAAGAGACGGGTGGGGGGCGAGGAGAAGGCAGGGGTAGGAGGCAAAGGGAATCTGAGGACCCGAAAGGTTGGAGGTGGGGTTGGAAAGA
CTGGGGCCCTGCGGGGAAGCGAGTCTGCAGCCTGAAACAGGAGTTTGTGGGTCAGAGTTTGTGGGTCAGAGTTTGTGGGGCTGGGATAGA
AACTCGGGGGATTGGCGTTCAGATGCTGACCACTTCCCTCTTCTCTGAGCAGTGTGACTTCACCGAAGACCAGACCGCAGAGTTCAAGGA
GGCCTTCCAGCTGTTTGACCGAACAGGTGATGGCAAGATCCTGTACAGCCAGTGTGGGGATGTGATGAGGGCCCTGGGCCAGAACCCTAC
CAACGCCGAGGTGCTCAAGGTCCTGGGGAACCCCAAGAGTGATGAGATCATTCCTCGCTCCATCCTGATGACCACCTTTGAGAGTAGCCA
TTACCTCCTTTGTGCCTTGGGAGATGGAGCGCTTTTCTACTTTGGGCTCAACATTGAGACAGGTCTGTTGAGCGACCGTAAGAAGGTGAC
TTTGGGCACCCAGCCCACCGTATTGAGGACTTTTCGTTCTCTTTCTACCACCAACGTCTTTGCTTGTTCTGACCGCCCCACTGTCATCTA
TAGCAGCAACCACAAATTGGTCTTCTCAAATGTCAACCTCAAGGAAGTGAACTACATGTGTCCCCTCAATTCAGATGGCTATCCTGACAG
CCTGGCGCTGGCCAACAATAGCACCCTCACCATTGGCACCATCGATGAGATCCAGAAGCTGCACATTCGCACAGTTCCCCTCTATGAGTC
TCCAAGGAAGATCTGCTACCAGGAAGTGTCCCAGTGTTTCGGGGTCCTCTCCAGCCGCATTGAAGTCCAAGACACGAGTGGGGGCACGAC
AGCCTTGAGGCCCAGCGCTAGCACCCAGGCTCTGTCCAGCAGTGTAAGCTCCAGCAAGCTGTTCTCCAGCAGCACTGCTCCTCATGAGAC
CTCCTTTGGAGAAGAGGTGGAGGTGCACAACCTACTTATCATTGACCAACACACCTTTGAAGTGCTTCATGCCCACCAGTTTCTGCAGAA
TGAATATGCCCTCAGTCTGGTTTCCTGCAAGCTGGGCAAAGACCCCAACACTTACTTCATTGTGGGCACAGCAATGGTGTATCCTGAAGA
GGCAGAGCCCAAGCAGGGTCGCATTGTGGTCTTTCAGTATTCGGATGGAAAACTACAGACTGTGGCTGAAAAGGAAGTGAAAGGGGCCGT
GTACTCTATGGTGGAATTTAACGGGAAGCTGTTAGCCAGCATCAATAGCACGGTGCGGCTCTATGAGTGGACAACAGAGAAGGAGCTGCG
CACTGAGTGCAACCACTACAACAACATCATGGCCCTCTACCTGAAGACCAAGGGCGACTTCATCCTGGTGGGCGACCTTATGCGCTCAGT
GCTGCTGCTTGCCTACAAGCCCATGGAAGGAAACTTTGAAGAGATTGCTCGAGACTTTAATCCCAACTGGATGAGTGCTGTGGAAATCTT
GGATGATGACAATTTTCTGGGGGCTGAAAATGCCTTTAACTTGTTTGTGTGTCAAAAGGATAGCGCTGCCACCACTGACGAGGAGCGGCA
GCACCTCCAGGAGGTTGGTCTTTTCCACCTGGGCGAGTTTGTCAATGTCTTTTGCCACGGCTCTCTGGTAATGCAGAATCTGGGTGAGAC
TTCCACCCCCACACAAGGCTCGGTGCTCTTCGGCACGGTCAACGGCATGATAGGGCTGGTGACCTCACTGTCAGAGAGCTGGTACAACCT
CCTGCTGGACATGCAGAATCGACTCAATAAAGTCATCAAAAGTGTGGGGAAGATCGAGCACTCCTTCTGGAGATCCTTTCACACCGAGCG
GAAGACAGAACCAGCCACAGGTTTCATCGACGGTGACTTGATTGAGAGTTTCCTGGATATTAGCCGCCCCAAGATGCAGGAGGTGGTGGC
AAACCTACAGTATGACGATGGCAGCGGTATGAAGCGAGAGGCCACTGCAGACGACCTCATCAAGGTTGTGGAGGAGCTAACTCGGATCCA
TTAGCCAAGGGCAGGGGGCCCCTTTGCTGACCCTCCCCAAAGGCTTTGCCCTGCTGCCCTCCCCCTCCTCTCCACCATCGTCTTCTTGGC
CATGGGAGGCCTTTCCCTAAGCCAGCTGCCCCCAGAGCCACAGTTCCCCTATGTGGAAGTGGGGCGGGCTTCATAGAGACTTGGGAATGA
GCTGAAGGTGAAACATTTTCTCCCTGGATTTTTACCAGTCTCACATGATTCCAGCCATCACCTTAGACCACCAAGCCTTGATTGGTGTTG
CCAGTTGTCCTCCTTCCGGGGAAGGATTTTGCAGTTCTTTGGCTGAAAGGAAGCTGTGCGTGTGTGTGTGTGTATGTGTGTGTGTGTATG
TGTATCTCACACTCATGCATTGTCCTCTTTTTATTTAGATTGGCAGTGTAGGGAGTTGTGGGTAGTGGGGAAGAGGGTTAGGAGGGTTTC
ATTGTCTGTGAAGTGAGACCTTCCTTTTACTTTTCTTCTATTGCCTCTGAGAGCATCAGGCCTAGAGGCCTGACTGCCAAGCCATGGGTA
GCCTGGGTGTAAAACCTGGAGATGGTGGATGATCCCCACGCCACAGCCCTTTTGTCTCTGCAAACTGCCTTCTTCGGAAAGAAGAAGGTG

>56462_56462_3_MYL6-DDB1_MYL6_chr12_56553514_ENST00000536128_DDB1_chr11_61081441_ENST00000301764_length(amino acids)=707AA_BP=151
MVGPRSWETGRIGDERQEETGGGRGEGRGRRQRESEDPKGWRWGWKDWGPAGKRVCSLKQEFVGQSLWVRVCGAGIETRGIGVQMLTTSL
FSEQCDFTEDQTAEFKEAFQLFDRTGDGKILYSQCGDVMRALGQNPTNAEVLKVLGNPKSDEIIPRSILMTTFESSHYLLCALGDGALFY
FGLNIETGLLSDRKKVTLGTQPTVLRTFRSLSTTNVFACSDRPTVIYSSNHKLVFSNVNLKEVNYMCPLNSDGYPDSLALANNSTLTIGT
IDEIQKLHIRTVPLYESPRKICYQEVSQCFGVLSSRIEVQDTSGGTTALRPSASTQALSSSVSSSKLFSSSTAPHETSFGEEVEVHNLLI
IDQHTFEVLHAHQFLQNEYALSLVSCKLGKDPNTYFIVGTAMVYPEEAEPKQGRIVVFQYSDGKLQTVAEKEVKGAVYSMVEFNGKLLAS
INSTVRLYEWTTEKELRTECNHYNNIMALYLKTKGDFILVGDLMRSVLLLAYKPMEGNFEEIARDFNPNWMSAVEILDDDNFLGAENAFN
LFVCQKDSAATTDEERQHLQEVGLFHLGEFVNVFCHGSLVMQNLGETSTPTQGSVLFGTVNGMIGLVTSLSESWYNLLLDMQNRLNKVIK

--------------------------------------------------------------
>56462_56462_4_MYL6-DDB1_MYL6_chr12_56553514_ENST00000547408_DDB1_chr11_61081441_ENST00000301764_length(transcript)=2564nt_BP=209nt
GCAGGAAAAGGTCCCGGAGAGCTGAGCAGTCAAGATGTGTGACTTCACCGAAGACCAGACCGCAGAGTTCAAGGAGGCCTTCCAGCTGTT
TGACCGAACAGGTGATGGCAAGATCCTGTACAGCCAGTGTGGGGATGTGATGAGGGCCCTGGGCCAGAACCCTACCAACGCCGAGGTGCT
CAAGGTCCTGGGGAACCCCAAGAGTGATGAGATCATTCCTCGCTCCATCCTGATGACCACCTTTGAGAGTAGCCATTACCTCCTTTGTGC
CTTGGGAGATGGAGCGCTTTTCTACTTTGGGCTCAACATTGAGACAGGTCTGTTGAGCGACCGTAAGAAGGTGACTTTGGGCACCCAGCC
CACCGTATTGAGGACTTTTCGTTCTCTTTCTACCACCAACGTCTTTGCTTGTTCTGACCGCCCCACTGTCATCTATAGCAGCAACCACAA
ATTGGTCTTCTCAAATGTCAACCTCAAGGAAGTGAACTACATGTGTCCCCTCAATTCAGATGGCTATCCTGACAGCCTGGCGCTGGCCAA
CAATAGCACCCTCACCATTGGCACCATCGATGAGATCCAGAAGCTGCACATTCGCACAGTTCCCCTCTATGAGTCTCCAAGGAAGATCTG
CTACCAGGAAGTGTCCCAGTGTTTCGGGGTCCTCTCCAGCCGCATTGAAGTCCAAGACACGAGTGGGGGCACGACAGCCTTGAGGCCCAG
CGCTAGCACCCAGGCTCTGTCCAGCAGTGTAAGCTCCAGCAAGCTGTTCTCCAGCAGCACTGCTCCTCATGAGACCTCCTTTGGAGAAGA
GGTGGAGGTGCACAACCTACTTATCATTGACCAACACACCTTTGAAGTGCTTCATGCCCACCAGTTTCTGCAGAATGAATATGCCCTCAG
TCTGGTTTCCTGCAAGCTGGGCAAAGACCCCAACACTTACTTCATTGTGGGCACAGCAATGGTGTATCCTGAAGAGGCAGAGCCCAAGCA
GGGTCGCATTGTGGTCTTTCAGTATTCGGATGGAAAACTACAGACTGTGGCTGAAAAGGAAGTGAAAGGGGCCGTGTACTCTATGGTGGA
ATTTAACGGGAAGCTGTTAGCCAGCATCAATAGCACGGTGCGGCTCTATGAGTGGACAACAGAGAAGGAGCTGCGCACTGAGTGCAACCA
CTACAACAACATCATGGCCCTCTACCTGAAGACCAAGGGCGACTTCATCCTGGTGGGCGACCTTATGCGCTCAGTGCTGCTGCTTGCCTA
CAAGCCCATGGAAGGAAACTTTGAAGAGATTGCTCGAGACTTTAATCCCAACTGGATGAGTGCTGTGGAAATCTTGGATGATGACAATTT
TCTGGGGGCTGAAAATGCCTTTAACTTGTTTGTGTGTCAAAAGGATAGCGCTGCCACCACTGACGAGGAGCGGCAGCACCTCCAGGAGGT
TGGTCTTTTCCACCTGGGCGAGTTTGTCAATGTCTTTTGCCACGGCTCTCTGGTAATGCAGAATCTGGGTGAGACTTCCACCCCCACACA
AGGCTCGGTGCTCTTCGGCACGGTCAACGGCATGATAGGGCTGGTGACCTCACTGTCAGAGAGCTGGTACAACCTCCTGCTGGACATGCA
GAATCGACTCAATAAAGTCATCAAAAGTGTGGGGAAGATCGAGCACTCCTTCTGGAGATCCTTTCACACCGAGCGGAAGACAGAACCAGC
CACAGGTTTCATCGACGGTGACTTGATTGAGAGTTTCCTGGATATTAGCCGCCCCAAGATGCAGGAGGTGGTGGCAAACCTACAGTATGA
CGATGGCAGCGGTATGAAGCGAGAGGCCACTGCAGACGACCTCATCAAGGTTGTGGAGGAGCTAACTCGGATCCATTAGCCAAGGGCAGG
GGGCCCCTTTGCTGACCCTCCCCAAAGGCTTTGCCCTGCTGCCCTCCCCCTCCTCTCCACCATCGTCTTCTTGGCCATGGGAGGCCTTTC
CCTAAGCCAGCTGCCCCCAGAGCCACAGTTCCCCTATGTGGAAGTGGGGCGGGCTTCATAGAGACTTGGGAATGAGCTGAAGGTGAAACA
TTTTCTCCCTGGATTTTTACCAGTCTCACATGATTCCAGCCATCACCTTAGACCACCAAGCCTTGATTGGTGTTGCCAGTTGTCCTCCTT
CCGGGGAAGGATTTTGCAGTTCTTTGGCTGAAAGGAAGCTGTGCGTGTGTGTGTGTGTATGTGTGTGTGTGTATGTGTATCTCACACTCA
TGCATTGTCCTCTTTTTATTTAGATTGGCAGTGTAGGGAGTTGTGGGTAGTGGGGAAGAGGGTTAGGAGGGTTTCATTGTCTGTGAAGTG
AGACCTTCCTTTTACTTTTCTTCTATTGCCTCTGAGAGCATCAGGCCTAGAGGCCTGACTGCCAAGCCATGGGTAGCCTGGGTGTAAAAC
CTGGAGATGGTGGATGATCCCCACGCCACAGCCCTTTTGTCTCTGCAAACTGCCTTCTTCGGAAAGAAGAAGGTGGGAGGATGTGAATTG

>56462_56462_4_MYL6-DDB1_MYL6_chr12_56553514_ENST00000547408_DDB1_chr11_61081441_ENST00000301764_length(amino acids)=614AA_BP=58
MCDFTEDQTAEFKEAFQLFDRTGDGKILYSQCGDVMRALGQNPTNAEVLKVLGNPKSDEIIPRSILMTTFESSHYLLCALGDGALFYFGL
NIETGLLSDRKKVTLGTQPTVLRTFRSLSTTNVFACSDRPTVIYSSNHKLVFSNVNLKEVNYMCPLNSDGYPDSLALANNSTLTIGTIDE
IQKLHIRTVPLYESPRKICYQEVSQCFGVLSSRIEVQDTSGGTTALRPSASTQALSSSVSSSKLFSSSTAPHETSFGEEVEVHNLLIIDQ
HTFEVLHAHQFLQNEYALSLVSCKLGKDPNTYFIVGTAMVYPEEAEPKQGRIVVFQYSDGKLQTVAEKEVKGAVYSMVEFNGKLLASINS
TVRLYEWTTEKELRTECNHYNNIMALYLKTKGDFILVGDLMRSVLLLAYKPMEGNFEEIARDFNPNWMSAVEILDDDNFLGAENAFNLFV
CQKDSAATTDEERQHLQEVGLFHLGEFVNVFCHGSLVMQNLGETSTPTQGSVLFGTVNGMIGLVTSLSESWYNLLLDMQNRLNKVIKSVG

--------------------------------------------------------------
>56462_56462_5_MYL6-DDB1_MYL6_chr12_56553514_ENST00000547649_DDB1_chr11_61081441_ENST00000301764_length(transcript)=2570nt_BP=215nt
ATTACTGCAGGAAAAGGTCCCGGAGAGCTGAGCAGTCAAGATGTGTGACTTCACCGAAGACCAGACCGCAGAGTTCAAGGAGGCCTTCCA
GCTGTTTGACCGAACAGGTGATGGCAAGATCCTGTACAGCCAGTGTGGGGATGTGATGAGGGCCCTGGGCCAGAACCCTACCAACGCCGA
GGTGCTCAAGGTCCTGGGGAACCCCAAGAGTGATGAGATCATTCCTCGCTCCATCCTGATGACCACCTTTGAGAGTAGCCATTACCTCCT
TTGTGCCTTGGGAGATGGAGCGCTTTTCTACTTTGGGCTCAACATTGAGACAGGTCTGTTGAGCGACCGTAAGAAGGTGACTTTGGGCAC
CCAGCCCACCGTATTGAGGACTTTTCGTTCTCTTTCTACCACCAACGTCTTTGCTTGTTCTGACCGCCCCACTGTCATCTATAGCAGCAA
CCACAAATTGGTCTTCTCAAATGTCAACCTCAAGGAAGTGAACTACATGTGTCCCCTCAATTCAGATGGCTATCCTGACAGCCTGGCGCT
GGCCAACAATAGCACCCTCACCATTGGCACCATCGATGAGATCCAGAAGCTGCACATTCGCACAGTTCCCCTCTATGAGTCTCCAAGGAA
GATCTGCTACCAGGAAGTGTCCCAGTGTTTCGGGGTCCTCTCCAGCCGCATTGAAGTCCAAGACACGAGTGGGGGCACGACAGCCTTGAG
GCCCAGCGCTAGCACCCAGGCTCTGTCCAGCAGTGTAAGCTCCAGCAAGCTGTTCTCCAGCAGCACTGCTCCTCATGAGACCTCCTTTGG
AGAAGAGGTGGAGGTGCACAACCTACTTATCATTGACCAACACACCTTTGAAGTGCTTCATGCCCACCAGTTTCTGCAGAATGAATATGC
CCTCAGTCTGGTTTCCTGCAAGCTGGGCAAAGACCCCAACACTTACTTCATTGTGGGCACAGCAATGGTGTATCCTGAAGAGGCAGAGCC
CAAGCAGGGTCGCATTGTGGTCTTTCAGTATTCGGATGGAAAACTACAGACTGTGGCTGAAAAGGAAGTGAAAGGGGCCGTGTACTCTAT
GGTGGAATTTAACGGGAAGCTGTTAGCCAGCATCAATAGCACGGTGCGGCTCTATGAGTGGACAACAGAGAAGGAGCTGCGCACTGAGTG
CAACCACTACAACAACATCATGGCCCTCTACCTGAAGACCAAGGGCGACTTCATCCTGGTGGGCGACCTTATGCGCTCAGTGCTGCTGCT
TGCCTACAAGCCCATGGAAGGAAACTTTGAAGAGATTGCTCGAGACTTTAATCCCAACTGGATGAGTGCTGTGGAAATCTTGGATGATGA
CAATTTTCTGGGGGCTGAAAATGCCTTTAACTTGTTTGTGTGTCAAAAGGATAGCGCTGCCACCACTGACGAGGAGCGGCAGCACCTCCA
GGAGGTTGGTCTTTTCCACCTGGGCGAGTTTGTCAATGTCTTTTGCCACGGCTCTCTGGTAATGCAGAATCTGGGTGAGACTTCCACCCC
CACACAAGGCTCGGTGCTCTTCGGCACGGTCAACGGCATGATAGGGCTGGTGACCTCACTGTCAGAGAGCTGGTACAACCTCCTGCTGGA
CATGCAGAATCGACTCAATAAAGTCATCAAAAGTGTGGGGAAGATCGAGCACTCCTTCTGGAGATCCTTTCACACCGAGCGGAAGACAGA
ACCAGCCACAGGTTTCATCGACGGTGACTTGATTGAGAGTTTCCTGGATATTAGCCGCCCCAAGATGCAGGAGGTGGTGGCAAACCTACA
GTATGACGATGGCAGCGGTATGAAGCGAGAGGCCACTGCAGACGACCTCATCAAGGTTGTGGAGGAGCTAACTCGGATCCATTAGCCAAG
GGCAGGGGGCCCCTTTGCTGACCCTCCCCAAAGGCTTTGCCCTGCTGCCCTCCCCCTCCTCTCCACCATCGTCTTCTTGGCCATGGGAGG
CCTTTCCCTAAGCCAGCTGCCCCCAGAGCCACAGTTCCCCTATGTGGAAGTGGGGCGGGCTTCATAGAGACTTGGGAATGAGCTGAAGGT
GAAACATTTTCTCCCTGGATTTTTACCAGTCTCACATGATTCCAGCCATCACCTTAGACCACCAAGCCTTGATTGGTGTTGCCAGTTGTC
CTCCTTCCGGGGAAGGATTTTGCAGTTCTTTGGCTGAAAGGAAGCTGTGCGTGTGTGTGTGTGTATGTGTGTGTGTGTATGTGTATCTCA
CACTCATGCATTGTCCTCTTTTTATTTAGATTGGCAGTGTAGGGAGTTGTGGGTAGTGGGGAAGAGGGTTAGGAGGGTTTCATTGTCTGT
GAAGTGAGACCTTCCTTTTACTTTTCTTCTATTGCCTCTGAGAGCATCAGGCCTAGAGGCCTGACTGCCAAGCCATGGGTAGCCTGGGTG
TAAAACCTGGAGATGGTGGATGATCCCCACGCCACAGCCCTTTTGTCTCTGCAAACTGCCTTCTTCGGAAAGAAGAAGGTGGGAGGATGT

>56462_56462_5_MYL6-DDB1_MYL6_chr12_56553514_ENST00000547649_DDB1_chr11_61081441_ENST00000301764_length(amino acids)=614AA_BP=58
MCDFTEDQTAEFKEAFQLFDRTGDGKILYSQCGDVMRALGQNPTNAEVLKVLGNPKSDEIIPRSILMTTFESSHYLLCALGDGALFYFGL
NIETGLLSDRKKVTLGTQPTVLRTFRSLSTTNVFACSDRPTVIYSSNHKLVFSNVNLKEVNYMCPLNSDGYPDSLALANNSTLTIGTIDE
IQKLHIRTVPLYESPRKICYQEVSQCFGVLSSRIEVQDTSGGTTALRPSASTQALSSSVSSSKLFSSSTAPHETSFGEEVEVHNLLIIDQ
HTFEVLHAHQFLQNEYALSLVSCKLGKDPNTYFIVGTAMVYPEEAEPKQGRIVVFQYSDGKLQTVAEKEVKGAVYSMVEFNGKLLASINS
TVRLYEWTTEKELRTECNHYNNIMALYLKTKGDFILVGDLMRSVLLLAYKPMEGNFEEIARDFNPNWMSAVEILDDDNFLGAENAFNLFV
CQKDSAATTDEERQHLQEVGLFHLGEFVNVFCHGSLVMQNLGETSTPTQGSVLFGTVNGMIGLVTSLSESWYNLLLDMQNRLNKVIKSVG

--------------------------------------------------------------
>56462_56462_6_MYL6-DDB1_MYL6_chr12_56553514_ENST00000548293_DDB1_chr11_61081441_ENST00000301764_length(transcript)=2536nt_BP=181nt
GTCAAGATGTGTGACTTCACCGAAGACCAGACCGCAGAGTTCAAGGAGGCCTTCCAGCTGTTTGACCGAACAGGTGATGGCAAGATCCTG
TACAGCCAGTGTGGGGATGTGATGAGGGCCCTGGGCCAGAACCCTACCAACGCCGAGGTGCTCAAGGTCCTGGGGAACCCCAAGAGTGAT
GAGATCATTCCTCGCTCCATCCTGATGACCACCTTTGAGAGTAGCCATTACCTCCTTTGTGCCTTGGGAGATGGAGCGCTTTTCTACTTT
GGGCTCAACATTGAGACAGGTCTGTTGAGCGACCGTAAGAAGGTGACTTTGGGCACCCAGCCCACCGTATTGAGGACTTTTCGTTCTCTT
TCTACCACCAACGTCTTTGCTTGTTCTGACCGCCCCACTGTCATCTATAGCAGCAACCACAAATTGGTCTTCTCAAATGTCAACCTCAAG
GAAGTGAACTACATGTGTCCCCTCAATTCAGATGGCTATCCTGACAGCCTGGCGCTGGCCAACAATAGCACCCTCACCATTGGCACCATC
GATGAGATCCAGAAGCTGCACATTCGCACAGTTCCCCTCTATGAGTCTCCAAGGAAGATCTGCTACCAGGAAGTGTCCCAGTGTTTCGGG
GTCCTCTCCAGCCGCATTGAAGTCCAAGACACGAGTGGGGGCACGACAGCCTTGAGGCCCAGCGCTAGCACCCAGGCTCTGTCCAGCAGT
GTAAGCTCCAGCAAGCTGTTCTCCAGCAGCACTGCTCCTCATGAGACCTCCTTTGGAGAAGAGGTGGAGGTGCACAACCTACTTATCATT
GACCAACACACCTTTGAAGTGCTTCATGCCCACCAGTTTCTGCAGAATGAATATGCCCTCAGTCTGGTTTCCTGCAAGCTGGGCAAAGAC
CCCAACACTTACTTCATTGTGGGCACAGCAATGGTGTATCCTGAAGAGGCAGAGCCCAAGCAGGGTCGCATTGTGGTCTTTCAGTATTCG
GATGGAAAACTACAGACTGTGGCTGAAAAGGAAGTGAAAGGGGCCGTGTACTCTATGGTGGAATTTAACGGGAAGCTGTTAGCCAGCATC
AATAGCACGGTGCGGCTCTATGAGTGGACAACAGAGAAGGAGCTGCGCACTGAGTGCAACCACTACAACAACATCATGGCCCTCTACCTG
AAGACCAAGGGCGACTTCATCCTGGTGGGCGACCTTATGCGCTCAGTGCTGCTGCTTGCCTACAAGCCCATGGAAGGAAACTTTGAAGAG
ATTGCTCGAGACTTTAATCCCAACTGGATGAGTGCTGTGGAAATCTTGGATGATGACAATTTTCTGGGGGCTGAAAATGCCTTTAACTTG
TTTGTGTGTCAAAAGGATAGCGCTGCCACCACTGACGAGGAGCGGCAGCACCTCCAGGAGGTTGGTCTTTTCCACCTGGGCGAGTTTGTC
AATGTCTTTTGCCACGGCTCTCTGGTAATGCAGAATCTGGGTGAGACTTCCACCCCCACACAAGGCTCGGTGCTCTTCGGCACGGTCAAC
GGCATGATAGGGCTGGTGACCTCACTGTCAGAGAGCTGGTACAACCTCCTGCTGGACATGCAGAATCGACTCAATAAAGTCATCAAAAGT
GTGGGGAAGATCGAGCACTCCTTCTGGAGATCCTTTCACACCGAGCGGAAGACAGAACCAGCCACAGGTTTCATCGACGGTGACTTGATT
GAGAGTTTCCTGGATATTAGCCGCCCCAAGATGCAGGAGGTGGTGGCAAACCTACAGTATGACGATGGCAGCGGTATGAAGCGAGAGGCC
ACTGCAGACGACCTCATCAAGGTTGTGGAGGAGCTAACTCGGATCCATTAGCCAAGGGCAGGGGGCCCCTTTGCTGACCCTCCCCAAAGG
CTTTGCCCTGCTGCCCTCCCCCTCCTCTCCACCATCGTCTTCTTGGCCATGGGAGGCCTTTCCCTAAGCCAGCTGCCCCCAGAGCCACAG
TTCCCCTATGTGGAAGTGGGGCGGGCTTCATAGAGACTTGGGAATGAGCTGAAGGTGAAACATTTTCTCCCTGGATTTTTACCAGTCTCA
CATGATTCCAGCCATCACCTTAGACCACCAAGCCTTGATTGGTGTTGCCAGTTGTCCTCCTTCCGGGGAAGGATTTTGCAGTTCTTTGGC
TGAAAGGAAGCTGTGCGTGTGTGTGTGTGTATGTGTGTGTGTGTATGTGTATCTCACACTCATGCATTGTCCTCTTTTTATTTAGATTGG
CAGTGTAGGGAGTTGTGGGTAGTGGGGAAGAGGGTTAGGAGGGTTTCATTGTCTGTGAAGTGAGACCTTCCTTTTACTTTTCTTCTATTG
CCTCTGAGAGCATCAGGCCTAGAGGCCTGACTGCCAAGCCATGGGTAGCCTGGGTGTAAAACCTGGAGATGGTGGATGATCCCCACGCCA
CAGCCCTTTTGTCTCTGCAAACTGCCTTCTTCGGAAAGAAGAAGGTGGGAGGATGTGAATTGTTAGTTTCTGAGTTTTACCAAATAAAGT

>56462_56462_6_MYL6-DDB1_MYL6_chr12_56553514_ENST00000548293_DDB1_chr11_61081441_ENST00000301764_length(amino acids)=614AA_BP=58
MCDFTEDQTAEFKEAFQLFDRTGDGKILYSQCGDVMRALGQNPTNAEVLKVLGNPKSDEIIPRSILMTTFESSHYLLCALGDGALFYFGL
NIETGLLSDRKKVTLGTQPTVLRTFRSLSTTNVFACSDRPTVIYSSNHKLVFSNVNLKEVNYMCPLNSDGYPDSLALANNSTLTIGTIDE
IQKLHIRTVPLYESPRKICYQEVSQCFGVLSSRIEVQDTSGGTTALRPSASTQALSSSVSSSKLFSSSTAPHETSFGEEVEVHNLLIIDQ
HTFEVLHAHQFLQNEYALSLVSCKLGKDPNTYFIVGTAMVYPEEAEPKQGRIVVFQYSDGKLQTVAEKEVKGAVYSMVEFNGKLLASINS
TVRLYEWTTEKELRTECNHYNNIMALYLKTKGDFILVGDLMRSVLLLAYKPMEGNFEEIARDFNPNWMSAVEILDDDNFLGAENAFNLFV
CQKDSAATTDEERQHLQEVGLFHLGEFVNVFCHGSLVMQNLGETSTPTQGSVLFGTVNGMIGLVTSLSESWYNLLLDMQNRLNKVIKSVG

--------------------------------------------------------------
>56462_56462_7_MYL6-DDB1_MYL6_chr12_56553514_ENST00000550697_DDB1_chr11_61081441_ENST00000301764_length(transcript)=2771nt_BP=416nt
CTCCCCCCACGACCCCCCCCACCTCCGAGCGGGTTCTGTGCCCAGGTGGCGCTGGAGAAAGGAACAGCGGACCCCGCCCAAGTCATTACT
AATGTAGCAATCGTCTGCATAAACCCAGGCCACGGTTCCTATTGGCTGAGTCCTCTGAGGGTGACGTCATCGGGACGTACTAAGACTAGG
GTTGGGCCGAGAGTCGGAGCCATTACTGCAGGAAAAGGTCCCGGAGAGCTGAGCAGTCAAGATGTGTGACTTCACCGAAGACCAGACCGC
AGAGTTCAAGGAGGCCTTCCAGCTGTTTGACCGAACAGGTGATGGCAAGATCCTGTACAGCCAGTGTGGGGATGTGATGAGGGCCCTGGG
CCAGAACCCTACCAACGCCGAGGTGCTCAAGGTCCTGGGGAACCCCAAGAGTGATGAGATCATTCCTCGCTCCATCCTGATGACCACCTT
TGAGAGTAGCCATTACCTCCTTTGTGCCTTGGGAGATGGAGCGCTTTTCTACTTTGGGCTCAACATTGAGACAGGTCTGTTGAGCGACCG
TAAGAAGGTGACTTTGGGCACCCAGCCCACCGTATTGAGGACTTTTCGTTCTCTTTCTACCACCAACGTCTTTGCTTGTTCTGACCGCCC
CACTGTCATCTATAGCAGCAACCACAAATTGGTCTTCTCAAATGTCAACCTCAAGGAAGTGAACTACATGTGTCCCCTCAATTCAGATGG
CTATCCTGACAGCCTGGCGCTGGCCAACAATAGCACCCTCACCATTGGCACCATCGATGAGATCCAGAAGCTGCACATTCGCACAGTTCC
CCTCTATGAGTCTCCAAGGAAGATCTGCTACCAGGAAGTGTCCCAGTGTTTCGGGGTCCTCTCCAGCCGCATTGAAGTCCAAGACACGAG
TGGGGGCACGACAGCCTTGAGGCCCAGCGCTAGCACCCAGGCTCTGTCCAGCAGTGTAAGCTCCAGCAAGCTGTTCTCCAGCAGCACTGC
TCCTCATGAGACCTCCTTTGGAGAAGAGGTGGAGGTGCACAACCTACTTATCATTGACCAACACACCTTTGAAGTGCTTCATGCCCACCA
GTTTCTGCAGAATGAATATGCCCTCAGTCTGGTTTCCTGCAAGCTGGGCAAAGACCCCAACACTTACTTCATTGTGGGCACAGCAATGGT
GTATCCTGAAGAGGCAGAGCCCAAGCAGGGTCGCATTGTGGTCTTTCAGTATTCGGATGGAAAACTACAGACTGTGGCTGAAAAGGAAGT
GAAAGGGGCCGTGTACTCTATGGTGGAATTTAACGGGAAGCTGTTAGCCAGCATCAATAGCACGGTGCGGCTCTATGAGTGGACAACAGA
GAAGGAGCTGCGCACTGAGTGCAACCACTACAACAACATCATGGCCCTCTACCTGAAGACCAAGGGCGACTTCATCCTGGTGGGCGACCT
TATGCGCTCAGTGCTGCTGCTTGCCTACAAGCCCATGGAAGGAAACTTTGAAGAGATTGCTCGAGACTTTAATCCCAACTGGATGAGTGC
TGTGGAAATCTTGGATGATGACAATTTTCTGGGGGCTGAAAATGCCTTTAACTTGTTTGTGTGTCAAAAGGATAGCGCTGCCACCACTGA
CGAGGAGCGGCAGCACCTCCAGGAGGTTGGTCTTTTCCACCTGGGCGAGTTTGTCAATGTCTTTTGCCACGGCTCTCTGGTAATGCAGAA
TCTGGGTGAGACTTCCACCCCCACACAAGGCTCGGTGCTCTTCGGCACGGTCAACGGCATGATAGGGCTGGTGACCTCACTGTCAGAGAG
CTGGTACAACCTCCTGCTGGACATGCAGAATCGACTCAATAAAGTCATCAAAAGTGTGGGGAAGATCGAGCACTCCTTCTGGAGATCCTT
TCACACCGAGCGGAAGACAGAACCAGCCACAGGTTTCATCGACGGTGACTTGATTGAGAGTTTCCTGGATATTAGCCGCCCCAAGATGCA
GGAGGTGGTGGCAAACCTACAGTATGACGATGGCAGCGGTATGAAGCGAGAGGCCACTGCAGACGACCTCATCAAGGTTGTGGAGGAGCT
AACTCGGATCCATTAGCCAAGGGCAGGGGGCCCCTTTGCTGACCCTCCCCAAAGGCTTTGCCCTGCTGCCCTCCCCCTCCTCTCCACCAT
CGTCTTCTTGGCCATGGGAGGCCTTTCCCTAAGCCAGCTGCCCCCAGAGCCACAGTTCCCCTATGTGGAAGTGGGGCGGGCTTCATAGAG
ACTTGGGAATGAGCTGAAGGTGAAACATTTTCTCCCTGGATTTTTACCAGTCTCACATGATTCCAGCCATCACCTTAGACCACCAAGCCT
TGATTGGTGTTGCCAGTTGTCCTCCTTCCGGGGAAGGATTTTGCAGTTCTTTGGCTGAAAGGAAGCTGTGCGTGTGTGTGTGTGTATGTG
TGTGTGTGTATGTGTATCTCACACTCATGCATTGTCCTCTTTTTATTTAGATTGGCAGTGTAGGGAGTTGTGGGTAGTGGGGAAGAGGGT
TAGGAGGGTTTCATTGTCTGTGAAGTGAGACCTTCCTTTTACTTTTCTTCTATTGCCTCTGAGAGCATCAGGCCTAGAGGCCTGACTGCC
AAGCCATGGGTAGCCTGGGTGTAAAACCTGGAGATGGTGGATGATCCCCACGCCACAGCCCTTTTGTCTCTGCAAACTGCCTTCTTCGGA

>56462_56462_7_MYL6-DDB1_MYL6_chr12_56553514_ENST00000550697_DDB1_chr11_61081441_ENST00000301764_length(amino acids)=614AA_BP=58
MCDFTEDQTAEFKEAFQLFDRTGDGKILYSQCGDVMRALGQNPTNAEVLKVLGNPKSDEIIPRSILMTTFESSHYLLCALGDGALFYFGL
NIETGLLSDRKKVTLGTQPTVLRTFRSLSTTNVFACSDRPTVIYSSNHKLVFSNVNLKEVNYMCPLNSDGYPDSLALANNSTLTIGTIDE
IQKLHIRTVPLYESPRKICYQEVSQCFGVLSSRIEVQDTSGGTTALRPSASTQALSSSVSSSKLFSSSTAPHETSFGEEVEVHNLLIIDQ
HTFEVLHAHQFLQNEYALSLVSCKLGKDPNTYFIVGTAMVYPEEAEPKQGRIVVFQYSDGKLQTVAEKEVKGAVYSMVEFNGKLLASINS
TVRLYEWTTEKELRTECNHYNNIMALYLKTKGDFILVGDLMRSVLLLAYKPMEGNFEEIARDFNPNWMSAVEILDDDNFLGAENAFNLFV
CQKDSAATTDEERQHLQEVGLFHLGEFVNVFCHGSLVMQNLGETSTPTQGSVLFGTVNGMIGLVTSLSESWYNLLLDMQNRLNKVIKSVG

--------------------------------------------------------------
>56462_56462_8_MYL6-DDB1_MYL6_chr12_56553514_ENST00000551589_DDB1_chr11_61081441_ENST00000301764_length(transcript)=2563nt_BP=208nt
CAGGAAAAGGTCCCGGAGAGCTGAGCAGTCAAGATGTGTGACTTCACCGAAGACCAGACCGCAGAGTTCAAGGAGGCCTTCCAGCTGTTT
GACCGAACAGGTGATGGCAAGATCCTGTACAGCCAGTGTGGGGATGTGATGAGGGCCCTGGGCCAGAACCCTACCAACGCCGAGGTGCTC
AAGGTCCTGGGGAACCCCAAGAGTGATGAGATCATTCCTCGCTCCATCCTGATGACCACCTTTGAGAGTAGCCATTACCTCCTTTGTGCC
TTGGGAGATGGAGCGCTTTTCTACTTTGGGCTCAACATTGAGACAGGTCTGTTGAGCGACCGTAAGAAGGTGACTTTGGGCACCCAGCCC
ACCGTATTGAGGACTTTTCGTTCTCTTTCTACCACCAACGTCTTTGCTTGTTCTGACCGCCCCACTGTCATCTATAGCAGCAACCACAAA
TTGGTCTTCTCAAATGTCAACCTCAAGGAAGTGAACTACATGTGTCCCCTCAATTCAGATGGCTATCCTGACAGCCTGGCGCTGGCCAAC
AATAGCACCCTCACCATTGGCACCATCGATGAGATCCAGAAGCTGCACATTCGCACAGTTCCCCTCTATGAGTCTCCAAGGAAGATCTGC
TACCAGGAAGTGTCCCAGTGTTTCGGGGTCCTCTCCAGCCGCATTGAAGTCCAAGACACGAGTGGGGGCACGACAGCCTTGAGGCCCAGC
GCTAGCACCCAGGCTCTGTCCAGCAGTGTAAGCTCCAGCAAGCTGTTCTCCAGCAGCACTGCTCCTCATGAGACCTCCTTTGGAGAAGAG
GTGGAGGTGCACAACCTACTTATCATTGACCAACACACCTTTGAAGTGCTTCATGCCCACCAGTTTCTGCAGAATGAATATGCCCTCAGT
CTGGTTTCCTGCAAGCTGGGCAAAGACCCCAACACTTACTTCATTGTGGGCACAGCAATGGTGTATCCTGAAGAGGCAGAGCCCAAGCAG
GGTCGCATTGTGGTCTTTCAGTATTCGGATGGAAAACTACAGACTGTGGCTGAAAAGGAAGTGAAAGGGGCCGTGTACTCTATGGTGGAA
TTTAACGGGAAGCTGTTAGCCAGCATCAATAGCACGGTGCGGCTCTATGAGTGGACAACAGAGAAGGAGCTGCGCACTGAGTGCAACCAC
TACAACAACATCATGGCCCTCTACCTGAAGACCAAGGGCGACTTCATCCTGGTGGGCGACCTTATGCGCTCAGTGCTGCTGCTTGCCTAC
AAGCCCATGGAAGGAAACTTTGAAGAGATTGCTCGAGACTTTAATCCCAACTGGATGAGTGCTGTGGAAATCTTGGATGATGACAATTTT
CTGGGGGCTGAAAATGCCTTTAACTTGTTTGTGTGTCAAAAGGATAGCGCTGCCACCACTGACGAGGAGCGGCAGCACCTCCAGGAGGTT
GGTCTTTTCCACCTGGGCGAGTTTGTCAATGTCTTTTGCCACGGCTCTCTGGTAATGCAGAATCTGGGTGAGACTTCCACCCCCACACAA
GGCTCGGTGCTCTTCGGCACGGTCAACGGCATGATAGGGCTGGTGACCTCACTGTCAGAGAGCTGGTACAACCTCCTGCTGGACATGCAG
AATCGACTCAATAAAGTCATCAAAAGTGTGGGGAAGATCGAGCACTCCTTCTGGAGATCCTTTCACACCGAGCGGAAGACAGAACCAGCC
ACAGGTTTCATCGACGGTGACTTGATTGAGAGTTTCCTGGATATTAGCCGCCCCAAGATGCAGGAGGTGGTGGCAAACCTACAGTATGAC
GATGGCAGCGGTATGAAGCGAGAGGCCACTGCAGACGACCTCATCAAGGTTGTGGAGGAGCTAACTCGGATCCATTAGCCAAGGGCAGGG
GGCCCCTTTGCTGACCCTCCCCAAAGGCTTTGCCCTGCTGCCCTCCCCCTCCTCTCCACCATCGTCTTCTTGGCCATGGGAGGCCTTTCC
CTAAGCCAGCTGCCCCCAGAGCCACAGTTCCCCTATGTGGAAGTGGGGCGGGCTTCATAGAGACTTGGGAATGAGCTGAAGGTGAAACAT
TTTCTCCCTGGATTTTTACCAGTCTCACATGATTCCAGCCATCACCTTAGACCACCAAGCCTTGATTGGTGTTGCCAGTTGTCCTCCTTC
CGGGGAAGGATTTTGCAGTTCTTTGGCTGAAAGGAAGCTGTGCGTGTGTGTGTGTGTATGTGTGTGTGTGTATGTGTATCTCACACTCAT
GCATTGTCCTCTTTTTATTTAGATTGGCAGTGTAGGGAGTTGTGGGTAGTGGGGAAGAGGGTTAGGAGGGTTTCATTGTCTGTGAAGTGA
GACCTTCCTTTTACTTTTCTTCTATTGCCTCTGAGAGCATCAGGCCTAGAGGCCTGACTGCCAAGCCATGGGTAGCCTGGGTGTAAAACC
TGGAGATGGTGGATGATCCCCACGCCACAGCCCTTTTGTCTCTGCAAACTGCCTTCTTCGGAAAGAAGAAGGTGGGAGGATGTGAATTGT

>56462_56462_8_MYL6-DDB1_MYL6_chr12_56553514_ENST00000551589_DDB1_chr11_61081441_ENST00000301764_length(amino acids)=614AA_BP=58
MCDFTEDQTAEFKEAFQLFDRTGDGKILYSQCGDVMRALGQNPTNAEVLKVLGNPKSDEIIPRSILMTTFESSHYLLCALGDGALFYFGL
NIETGLLSDRKKVTLGTQPTVLRTFRSLSTTNVFACSDRPTVIYSSNHKLVFSNVNLKEVNYMCPLNSDGYPDSLALANNSTLTIGTIDE
IQKLHIRTVPLYESPRKICYQEVSQCFGVLSSRIEVQDTSGGTTALRPSASTQALSSSVSSSKLFSSSTAPHETSFGEEVEVHNLLIIDQ
HTFEVLHAHQFLQNEYALSLVSCKLGKDPNTYFIVGTAMVYPEEAEPKQGRIVVFQYSDGKLQTVAEKEVKGAVYSMVEFNGKLLASINS
TVRLYEWTTEKELRTECNHYNNIMALYLKTKGDFILVGDLMRSVLLLAYKPMEGNFEEIARDFNPNWMSAVEILDDDNFLGAENAFNLFV
CQKDSAATTDEERQHLQEVGLFHLGEFVNVFCHGSLVMQNLGETSTPTQGSVLFGTVNGMIGLVTSLSESWYNLLLDMQNRLNKVIKSVG

--------------------------------------------------------------

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Fusion Gene PPI Analysis for MYL6-DDB1


check button Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in

ChiPPI page.


check button Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160)
HgeneHgene's interactorsTgeneTgene's interactors


check button - Retained PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenStill interaction with
TgeneDDB1chr12:56553514chr11:61081441ENST000003017641327771_1140584.33333333333341141.0CDT1 and CUL4A


check button - Lost PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with
TgeneDDB1chr12:56553514chr11:61081441ENST0000030176413272_768584.33333333333341141.0CDT1


check button - Retained PPIs, but lost function due to frame-shift fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


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Related Drugs for MYL6-DDB1


check button Drugs targeting genes involved in this fusion gene.
(DrugBank Version 5.1.8 2021-05-08)
PartnerGeneUniProtAccDrugBank IDDrug nameDrug activityDrug typeDrug status

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Related Diseases for MYL6-DDB1


check button Diseases associated with fusion partners.
(DisGeNet 4.0)
PartnerGeneDisease IDDisease name# pubmedsSource