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Center for Computational Systems Medicine
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Fusion Gene Summary

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Fusion Gene ORF analysis

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Fusion Genomic Features

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Fusion Protein Features

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Fusion Gene Sequence

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Fusion Gene PPI analysis

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Related Drugs

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Related Diseases

Fusion gene:MYO18A-MYO1D (FusionGDB2 ID:56594)

Fusion Gene Summary for MYO18A-MYO1D

check button Fusion gene summary
Fusion gene informationFusion gene name: MYO18A-MYO1D
Fusion gene ID: 56594
HgeneTgene
Gene symbol

MYO18A

MYO1D

Gene ID

399687

4642

Gene namemyosin XVIIIAmyosin ID
SynonymsMAJN|MYSPDZ|SP-R210|SPR210PPP1R108|myr4
Cytomap

17q11.2

17q11.2

Type of geneprotein-codingprotein-coding
Descriptionunconventional myosin-XVIIIaSP-A receptor subunit SP-R210 alphaSmolecule associated with JAK3 N-terminusmyosin 18Amyosin containing PDZ domainmyosin containing a PDZ domainsurfactant protein receptor SP-R210unconventional myosin-Idmyosin-I gammaprotein phosphatase 1, regulatory subunit 108
Modification date2020031320200313
UniProtAcc

Q92614

O94832

Ensembl transtripts involved in fusion geneENST00000354329, ENST00000527372, 
ENST00000531253, ENST00000533112, 
ENST00000529578, 		ENST00000579584, 
ENST00000583621, ENST00000584232, 
ENST00000318217, ENST00000394649, 
Fusion gene scores* DoF score26 X 21 X 12=655228 X 20 X 9=5040
# samples 2729
** MAII scorelog2(27/6552*10)=-4.60090404459018
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0		log2(29/5040*10)=-4.11929892837234
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0
Context

PubMed: MYO18A [Title/Abstract] AND MYO1D [Title/Abstract] AND fusion [Title/Abstract]

Most frequent breakpointMYO18A(27409334)-MYO1D(30821933), # samples:1
Anticipated loss of major functional domain due to fusion event.MYO18A-MYO1D seems lost the major protein functional domain in Hgene partner, which is a essential gene due to the frame-shifted ORF.
MYO18A-MYO1D seems lost the major protein functional domain in Tgene partner, which is a essential gene due to the frame-shifted ORF.
* DoF score (Degree of Frequency) = # partners X # break points X # cancer types
** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)

check button Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez
PartnerGeneGO IDGO termPubMed ID
TgeneMYO1D

GO:0010923

negative regulation of phosphatase activity

19389623


check buttonFusion gene breakpoints across MYO18A (5'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check buttonFusion gene breakpoints across MYO1D (3'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check button Fusion gene information from two resources (ChiTars 5.0 and ChimerDB 4.0)
* All genome coordinats were lifted-over on hg19.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
SourceDiseaseSampleHgeneHchrHbpHstrandTgeneTchrTbpTstrand
ChimerDB4COADTCGA-D5-6929-01AMYO18Achr17

27409334

-MYO1Dchr17

30821933

-


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Fusion Gene ORF analysis for MYO18A-MYO1D

check button Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
ORFHenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrand
5CDS-intronENST00000354329ENST00000579584MYO18Achr17

27409334

-MYO1Dchr17

30821933

-
5CDS-intronENST00000354329ENST00000583621MYO18Achr17

27409334

-MYO1Dchr17

30821933

-
5CDS-intronENST00000354329ENST00000584232MYO18Achr17

27409334

-MYO1Dchr17

30821933

-
5CDS-intronENST00000527372ENST00000579584MYO18Achr17

27409334

-MYO1Dchr17

30821933

-
5CDS-intronENST00000527372ENST00000583621MYO18Achr17

27409334

-MYO1Dchr17

30821933

-
5CDS-intronENST00000527372ENST00000584232MYO18Achr17

27409334

-MYO1Dchr17

30821933

-
5CDS-intronENST00000531253ENST00000579584MYO18Achr17

27409334

-MYO1Dchr17

30821933

-
5CDS-intronENST00000531253ENST00000583621MYO18Achr17

27409334

-MYO1Dchr17

30821933

-
5CDS-intronENST00000531253ENST00000584232MYO18Achr17

27409334

-MYO1Dchr17

30821933

-
5CDS-intronENST00000533112ENST00000579584MYO18Achr17

27409334

-MYO1Dchr17

30821933

-
5CDS-intronENST00000533112ENST00000583621MYO18Achr17

27409334

-MYO1Dchr17

30821933

-
5CDS-intronENST00000533112ENST00000584232MYO18Achr17

27409334

-MYO1Dchr17

30821933

-
5UTR-3CDSENST00000529578ENST00000318217MYO18Achr17

27409334

-MYO1Dchr17

30821933

-
5UTR-3CDSENST00000529578ENST00000394649MYO18Achr17

27409334

-MYO1Dchr17

30821933

-
5UTR-intronENST00000529578ENST00000579584MYO18Achr17

27409334

-MYO1Dchr17

30821933

-
5UTR-intronENST00000529578ENST00000583621MYO18Achr17

27409334

-MYO1Dchr17

30821933

-
5UTR-intronENST00000529578ENST00000584232MYO18Achr17

27409334

-MYO1Dchr17

30821933

-
Frame-shiftENST00000354329ENST00000318217MYO18Achr17

27409334

-MYO1Dchr17

30821933

-
Frame-shiftENST00000527372ENST00000318217MYO18Achr17

27409334

-MYO1Dchr17

30821933

-
Frame-shiftENST00000531253ENST00000318217MYO18Achr17

27409334

-MYO1Dchr17

30821933

-
Frame-shiftENST00000533112ENST00000318217MYO18Achr17

27409334

-MYO1Dchr17

30821933

-
In-frameENST00000354329ENST00000394649MYO18Achr17

27409334

-MYO1Dchr17

30821933

-
In-frameENST00000527372ENST00000394649MYO18Achr17

27409334

-MYO1Dchr17

30821933

-
In-frameENST00000531253ENST00000394649MYO18Achr17

27409334

-MYO1Dchr17

30821933

-
In-frameENST00000533112ENST00000394649MYO18Achr17

27409334

-MYO1Dchr17

30821933

-

check buttonORFfinder result based on the fusion transcript sequence of in-frame fusion genes.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandSeq length
(transcript)		BP loci
(transcript)		Predicted start
(transcript)		Predicted stop
(transcript)		Seq length
(amino acids)
ENST00000354329MYO18Achr1727409334-ENST00000394649MYO1Dchr1730821933-8485617815863342058
ENST00000533112MYO18Achr1727409334-ENST00000394649MYO1Dchr1730821933-8433612626262822006
ENST00000531253MYO18Achr1727409334-ENST00000394649MYO1Dchr1730821933-8415610813362642043
ENST00000527372MYO18Achr1727409334-ENST00000394649MYO1Dchr1730821933-8508620118163572058

check buttonDeepORF prediction of the coding potential based on the fusion transcript sequence of in-frame fusion genes. DeepORF is a coding potential classifier based on convolutional neural network by comparing the real Ribo-seq data. If the no-coding score < 0.5 and coding score > 0.5, then the in-frame fusion transcript is predicted as being likely translated.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandNo-coding scoreCoding score
ENST00000354329ENST00000394649MYO18Achr1727409334-MYO1Dchr1730821933-0.0081066460.9918934
ENST00000533112ENST00000394649MYO18Achr1727409334-MYO1Dchr1730821933-0.0138250770.98617494
ENST00000531253ENST00000394649MYO18Achr1727409334-MYO1Dchr1730821933-0.0100859060.98991406
ENST00000527372ENST00000394649MYO18Achr1727409334-MYO1Dchr1730821933-0.0084779410.9915221

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Fusion Genomic Features for MYO18A-MYO1D


check buttonFusionAI prediction of the potential fusion gene breakpoint based on the pre-mature RNA sequence context (+/- 5kb of individual partner genes, total 20kb length sequence). FusionAI is a fusion gene breakpoint classifier based on convolutional neural network by comparing the fusion positive and negative sequence context of ~ 20K fusion gene data. From here, we can have the relative potentency of the 20K genomic sequence how individual sequnce will be likely used as the gene fusion breakpoints.
HgeneHchrHbpHstrandTgeneTchrTbpTstrand1-pp (fusion gene breakpoint)

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions. We integrated a total of 44 different types of human genomic feature loci information across five big categories including virus integration sites, repeats, structural variants, chromatin states, and gene expression regulation. More details are in help page.
genomic feature

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions that are ovelapped with the top 1% feature importance score regions. More details are in help page.

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Fusion Protein Features for MYO18A-MYO1D


check button Four levels of functional features of fusion genes
Go to FGviewer search page for the most frequent breakpoint (https://ccsmweb.uth.edu/FGviewer/chr17:27409334/chr17:30821933)
- FGviewer provides the online visualization of the retention search of the protein functional features across DNA, RNA, protein, and pathological levels.
- How to search
1. Put your fusion gene symbol.
2. Press the tab key until there will be shown the breakpoint information filled.
4. Go down and press 'Search' tab twice.
4. Go down to have the hyperlink of the search result.
5. Click the hyperlink.
6. See the FGviewer result for your fusion gene.
FGviewer

check buttonMain function of each fusion partner protein. (from UniProt)
HgeneTgene
MYO18A

Q92614

MYO1D

O94832

FUNCTION: May link Golgi membranes to the cytoskeleton and participate in the tensile force required for vesicle budding from the Golgi. Thereby, may play a role in Golgi membrane trafficking and could indirectly give its flattened shape to the Golgi apparatus (PubMed:19837035, PubMed:23345592). Alternatively, in concert with LURAP1 and CDC42BPA/CDC42BPB, has been involved in modulating lamellar actomyosin retrograde flow that is crucial to cell protrusion and migration (PubMed:18854160). May be involved in the maintenance of the stromal cell architectures required for cell to cell contact (By similarity). Regulates trafficking, expression, and activation of innate immune receptors on macrophages. Plays a role to suppress inflammatory responsiveness of macrophages via a mechanism that modulates CD14 trafficking (PubMed:25965346). Acts as a receptor of surfactant-associated protein A (SFTPA1/SP-A) and plays an important role in internalization and clearance of SFTPA1-opsonized S.aureus by alveolar macrophages (PubMed:16087679, PubMed:21123169). Strongly enhances natural killer cell cytotoxicity (PubMed:27467939). {ECO:0000250|UniProtKB:Q9JMH9, ECO:0000269|PubMed:16087679, ECO:0000269|PubMed:18854160, ECO:0000269|PubMed:19837035, ECO:0000269|PubMed:21123169, ECO:0000269|PubMed:23345592, ECO:0000269|PubMed:25965346, ECO:0000269|PubMed:27467939}.FUNCTION: Unconventional myosin that functions as actin-based motor protein with ATPase activity (By similarity). Plays a role in endosomal protein trafficking, and especially in the transfer of cargo proteins from early to recycling endosomes (By similarity). Required for normal planar cell polarity in ciliated tracheal cells, for normal rotational polarity of cilia, and for coordinated, unidirectional ciliary movement in the trachea. Required for normal, polarized cilia organization in brain ependymal epithelial cells (By similarity). {ECO:0000250|UniProtKB:F1PRN2, ECO:0000250|UniProtKB:Q63357}.

check buttonRetention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at

download page


* Minus value of BPloci means that the break pointn is located before the CDS.
- In-frame and retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneMYO18Achr17:27409334chr17:30821933ENST00000527372-41421246_197120062055.0Coiled coilOntology_term=ECO:0000255
HgeneMYO18Achr17:27409334chr17:30821933ENST00000531253-40411246_197119912040.0Coiled coilOntology_term=ECO:0000255
HgeneMYO18Achr17:27409334chr17:30821933ENST00000527372-41426_2520062055.0Compositional biasNote=Lys-rich
HgeneMYO18Achr17:27409334chr17:30821933ENST00000531253-40416_2519912040.0Compositional biasNote=Lys-rich
HgeneMYO18Achr17:27409334chr17:30821933ENST00000533112-39406_2519542003.0Compositional biasNote=Lys-rich
HgeneMYO18Achr17:27409334chr17:30821933ENST00000527372-41421188_121720062055.0DomainIQ
HgeneMYO18Achr17:27409334chr17:30821933ENST00000527372-4142220_31120062055.0DomainPDZ
HgeneMYO18Achr17:27409334chr17:30821933ENST00000527372-4142349_40120062055.0DomainMyosin N-terminal SH3-like
HgeneMYO18Achr17:27409334chr17:30821933ENST00000527372-4142405_118520062055.0DomainMyosin motor
HgeneMYO18Achr17:27409334chr17:30821933ENST00000531253-40411188_121719912040.0DomainIQ
HgeneMYO18Achr17:27409334chr17:30821933ENST00000531253-4041220_31119912040.0DomainPDZ
HgeneMYO18Achr17:27409334chr17:30821933ENST00000531253-4041349_40119912040.0DomainMyosin N-terminal SH3-like
HgeneMYO18Achr17:27409334chr17:30821933ENST00000531253-4041405_118519912040.0DomainMyosin motor
HgeneMYO18Achr17:27409334chr17:30821933ENST00000533112-39401188_121719542003.0DomainIQ
HgeneMYO18Achr17:27409334chr17:30821933ENST00000533112-3940220_31119542003.0DomainPDZ
HgeneMYO18Achr17:27409334chr17:30821933ENST00000533112-3940349_40119542003.0DomainMyosin N-terminal SH3-like
HgeneMYO18Achr17:27409334chr17:30821933ENST00000533112-3940405_118519542003.0DomainMyosin motor
HgeneMYO18Achr17:27409334chr17:30821933ENST00000527372-4142498_50520062055.0Nucleotide bindingATP
HgeneMYO18Achr17:27409334chr17:30821933ENST00000531253-4041498_50519912040.0Nucleotide bindingATP
HgeneMYO18Achr17:27409334chr17:30821933ENST00000533112-3940498_50519542003.0Nucleotide bindingATP

- In-frame and not-retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneMYO18Achr17:27409334chr17:30821933ENST00000533112-39401246_197119542003.0Coiled coilOntology_term=ECO:0000255
TgeneMYO1Dchr17:27409334chr17:30821933ENST000003182172022699_7199541007.0DomainIQ 1
TgeneMYO1Dchr17:27409334chr17:30821933ENST000003182172022721_7419541007.0DomainIQ 2
TgeneMYO1Dchr17:27409334chr17:30821933ENST000003182172022812_10059541007.0DomainTH1
TgeneMYO1Dchr17:27409334chr17:30821933ENST0000031821720229_6959541007.0DomainMyosin motor
TgeneMYO1Dchr17:27409334chr17:30821933ENST000003182172022102_1099541007.0Nucleotide bindingATP
TgeneMYO1Dchr17:27409334chr17:30821933ENST000003182172022572_5949541007.0RegionActin-binding


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Fusion Gene Sequence for MYO18A-MYO1D


check button For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. To have fusion amino acid sequence, we ran ORFfinder and chose the longest ORF among the all predicted ones.
>56594_56594_1_MYO18A-MYO1D_MYO18A_chr17_27409334_ENST00000354329_MYO1D_chr17_30821933_ENST00000394649_length(transcript)=8485nt_BP=6178nt
TCCATCCCTGACCGGGCCGAGGCTGCTGGATGCCGCGTCTCCGCTTCTGCTGCCTGCCGGGCGGGCTCCGGTGGCCGCAGCAAAGTGGGG
CACCAAGGCCCTGTGCTAAGCACTCATAATCCTCTGGGGGTGCTACCCCTACAAACAGCACCCCCACCATGTTTAACCTAATGAAGAAAG
ACAAGGACAAAGATGGCGGGCGGAAGGAGAAGAAGGAGAAAAAGGAGAAAAAGGAGCGGATGTCAGCGGCAGAGCTTCGGAGCCTGGAGG
AGATGAGCCTGCGACGTGGCTTCTTCAACCTGAACCGCTCCTCCAAGCGTGAATCCAAGACGCGCCTGGAAATCTCCAACCCCATCCCCA
TCAAGGTGGCCAGCGGCTCTGACCTGCACCTGACTGACATTGACTCCGATAGTAACCGGGGCAGCGTCATCCTGGACTCGGGCCACCTAA
GTACAGCCAGCTCCAGCGATGACCTCAAGGGTGAGGAGGGTAGCTTCCGTGGCTCGGTGCTGCAGCGGGCAGCCAAGTTCGGCTCACTGG
CCAAGCAGAACTCACAGATGATTGTCAAGCGCTTTTCCTTCTCCCAGCGTAGCCGGGATGAGAGCGCCTCAGAAACCTCGACGCCCTCAG
AGCACTCTGCCGCCCCCTCGCCACAGGTGGAGGTGAGGACTCTAGAGGGACAGCTGGTGCAGCATCCTGGCCCAGGCATCCCTCGACCAG
GGCACCGATCCCGAGCCCCTGAGCTAGTGACTAAAAAGTTCCCAGTCGACCTGCGCCTGCCCCCCGTGGTGCCCCTGCCCCCACCTACCC
TCCGGGAGCTGGAGCTGCAACGACGGCCCACTGGAGACTTTGGCTTCTCCCTGCGGCGCACAACCATGCTGGATCGGGGCCCCGAGGGCC
AGGCCTGTCGGCGTGTGGTCCACTTTGCTGAGCCTGGTGCAGGCACCAAGGACCTGGCCCTGGGGCTGGTGCCAGGAGATCGACTGGTGG
AGATTAATGGGCACAATGTGGAGAGCAAGTCCAGGGATGAGATTGTGGAGATGATCCGGCAGTCAGGGGACAGCGTGCGGCTCAAGGTGC
AGCCCATTCCAGAGCTCAGCGAGCTCAGCAGGAGCTGGCTGCGGAGCGGCGAGGGACCTCGCAGGGAGCCATCCGATGCGAAAACAGAAG
AACAGATTGCAGCAGAAGAGGCCTGGAATGAGACGGAGAAGGTGTGGCTGGTCCATAGGGACGGCTTCTCACTGGCCAGTCAACTCAAAT
CTGAGGAGCTCAACTTGCCTGAGGGGAAGGTGCGTGTGAAGCTGGACCACGATGGGGCCATCCTGGATGTGGATGAGGATGACGTTGAGA
AGGCTAATGCTCCCTCCTGCGACCGTCTGGAGGATCTGGCCTCACTGGTGTACCTCAATGAGTCCAGCGTCCTGCACACCTTGCGCCAGC
GCTATGGCGCTAGCCTGCTGCACACGTATGCTGGCCCCAGCCTGCTGGTTCTTGGCCCCCGTGGGGCCCCTGCTGTGTACTCTGAGAAGG
TGATGCACATGTTCAAGGGTTGTCGGCGGGAGGACATGGCACCCCACATCTATGCAGTGGCCCAGACCGCATACAGGGCGATGCTGATGA
GCCGTCAGGATCAGTCAATCATCCTCCTGGGCAGTAGTGGCAGTGGCAAGACCACCAGCTGCCAGCATCTGGTGCAGTACCTGGCCACCA
TCGCGGGCATCAGCGGGAACAAGGTGTTTTCTGTGGAGAAGTGGCAGGCTCTGTACACCCTCCTGGAAGCCTTTGGGAACAGCCCCACCA
TCATTAATGGCAATGCCACCCGCTTCTCCCAGATCCTCTCCCTGGACTTTGACCAAGCTGGCCAGGTGGCCTCAGCCTCCATTCAGACAA
TGCTTCTGGAGAAGCTGCGTGTGGCTCGGCGCCCAGCCAGTGAAGCCACATTCAACGTCTTCTACTACCTGCTGGCCTGTGGGGATGGCA
CCCTCAGGACAGAGCTCCACCTCAACCACTTGGCAGAGAACAATGTGTTTGGGATTGTGCCACTGGCCAAGCCTGAGGAAAAGCAGAAGG
CAGCTCAGCAGTTTAGTAAGCTGCAGGCGGCCATGAAGGTGCTGGGCATCTCCCCCGATGAACAGAAGGCCTGCTGGTTCATTCTGGCTG
CCATCTACCACCTGGGGGCTGCGGGAGCCACCAAAGTCCACTCCACAGCTGGGCGCAAGCAGTTTGCCCGCCATGAGTGGGCCCAGAAGG
CTGCGTACCTACTGGGCTGCAGCCTGGAGGAGCTGTCCTCAGCCATCTTCAAGCACCAGCACAAGGGTGGCACCCTGCAGCGCTCCACCT
CCTTCCGCCAGGGCCCCGAGGAGAGTGGCCTGGGAGATGGGACAGGCCCGAAACTGAGTGCACTGGAGTGCCTTGAGGGCATGGCGGCCG
GCCTCTACAGCGAGCTCTTCACCCTTCTCGTCTCCCTGGTGAATAGGGCTCTCAAGTCCAGCCAGCACTCACTCTGCTCCATGATGATTG
TCGACACCCCGGGCTTCCAGAACCCTGAGCAGGGTGGGTCAGCCCGCGGAGCCTCCTTTGAGGAGCTGTGCCACAACTACACCCAAGACC
GGCTGCAGAGGCTCTTCCACGAGCGCACCTTCGTGCAGGAGTTGGAAAGATACAAGGAGGAGAACATCGAGCTGGCGTTTGACGACTTGG
AACCCCCGACGGATGACTCTGTGGCTGCTGTGGACCAGGCCTCCCATCAGTCCCTGGTCCGCTCGCTGGCCCGCACAGACGAGGCGAGGG
GCCTGCTCTGGCTATTGGAAGAGGAGGCTCTGGTGCCAGGGGCCAGTGAGGACACCCTCCTGGAGCGCCTTTTCTCCTATTATGGCCCCC
AGGAAGGTGACAAAAAAGGCCAAAGCCCCCTTCTGCACAGCAGCAAACCACACCACTTTCTCCTGGGCCACAGCCATGGCACCAACTGGG
TAGAGTACAATGTGACTGGCTGGCTGAACTACACCAAGCAGAACCCAGCCACCCAGAATGCCCCCCGGCTCCTGCAGGACTCCCAGAAAA
AAATCATCAGCAACCTGTTTCTGGGCCGCGCAGGCAGTGCCACGGTGCTCTCTGGCTCCATCGCGGGCCTGGAGGGCGGCTCGCAGCTGG
CACTGCGCCGGGCCACCAGCATGCGGAAAACCTTTACCACAGGCATGGCGGCTGTCAAAAAGAAGTCACTGTGCATCCAGATGAAGCTAC
AGGTGGACGCCCTCATCGACACCATCAAGAAGTCAAAGCTGCATTTTGTGCACTGCTTCCTGCCTGTAGCTGAGGGCTGGGCTGGGGAGC
CCCGTTCCGCCTCCTCCCGCCGAGTCAGCAGCAGCAGTGAGCTGGACCTGCCCTCGGGAGACCACTGCGAGGCTGGGCTCCTGCAGCTCG
ACGTGCCCCTGCTCCGCACCCAGCTCCGCGGCTCCCGCCTGCTCGATGCCATGCGCATGTACCGCCAAGGTTACCCTGACCACATGGTGT
TTTCCGAGTTCCGCCGCCGCTTTGATGTCCTGGCCCCGCACCTGACCAAGAAACACGGGCGTAACTACATCGTGGTGGATGAAAGGCGGG
CAGTGGAGGAGCTGCTGGAGTGCTTGGATCTGGAGAAGAGCAGCTGCTGCATGGGCCTGAGCCGGGTGTTCTTCCGGGCGGGCACCTTGG
CACGGCTGGAGGAGCAGCGGGATGAACAAACCAGCAGGAACCTAACCCTGTTCCAAGCAGCCTGCAGGGGCTACCTGGCCCGCCAGCACT
TCAAGAAGAGAAAGATCCAGGACCTGGCCATTCGCTGTGTACAGAAGAACATCAAGAAGAACAAAGGGGTGAAGGACTGGCCCTGGTGGA
AGCTTTTTACCACAGTGAGGCCCCTCATCGAAGTACAGCTGTCAGAGGAGCAGATCCGGAACAAAGACGAGGAGATCCAGCAGCTGCGGA
GCAAGCTCGAGAAGGCGGAGAAGGAGAGGAACGAGCTGCGGCTCAACAGTGACCGGCTGGAGAGCCGGATCTCAGAGCTGACATCGGAGC
TGACAGATGAGCGTAACACAGGAGAGTCCGCCTCCCAGCTGCTGGACGCGGAGACAGCAGAGAGGCTCCGGGCTGAGAAGGAGATGAAGG
AACTGCAGACCCAGTACGATGCACTGAAGAAGCAGATGGAGGTTATGGAAATGGAGGTGATGGAGGCCCGTCTCATCCGGGCAGCGGAGA
TCAACGGGGAAGTGGATGATGATGATGCAGGTGGCGAGTGGCGGCTGAAGTATGAGCGGGCTGTGCGGGAGGTGGACTTCACCAAGAAAC
GGCTCCAGCAGGAGTTTGAGGACAAGCTGGAGGTGGAGCAGCAGAACAAGAGGCAGCTGGAACGGCGGCTCGGGGACCTGCAGGCAGATA
GTGAGGAGAGTCAGCGGGCTCTGCAGCAGCTCAAGAAGAAGTGCCAGCGACTGACGGCTGAGCTGCAAGACACCAAGCTGCACCTGGAGG
GCCAGCAGGTCCGCAACCACGAACTGGAGAAGAAGCAGAGGAGGTTTGACAGTGAGCTCTCGCAGGCGCATGAGGAGGCCCAGCGGGAGA
AGCTGCAGCGGGAGAAGCTGCAGCGGGAGAAGGACATGCTCCTCGCTGAGGCTTTCAGCCTGAAGCAGCAACTAGAGGAAAAAGACATGG
ACATTGCAGGGTTCACCCAGAAGGTTGTGTCTCTAGAGGCAGAGCTCCAGGACATTTCTTCCCAAGAGTCCAAGGATGAGGCTTCTCTGG
CCAAGGTCAAGAAACAGCTCCGGGACCTGGAGGCCAAAGTCAAGGATCAGGAAGAAGAGCTGGATGAGCAGGCAGGGACCATCCAGATGC
TGGAACAGGCCAAGCTGCGTCTGGAGATGGAGATGGAGCGGATGAGACAGACCCATTCTAAGGAGATGGAGAGTCGGGATGAGGAGGTGG
AGGAGGCCCGGCAGTCGTGTCAGAAGAAGTTAAAACAGATGGAGGTGCAGCTAGAGGAAGAGTATGAGGACAAGCAGAAGGTTCTGCGAG
AGAAGCGGGAGCTGGAGGGCAAGCTCGCCACCCTCAGCGACCAGGTGAACCGGCGGGACTTTGAGTCAGAGAAGCGGCTGCGGAAGGACC
TGAAGCGCACCAAGGCCCTGCTGGCAGATGCCCAGCTCATGCTGGACCACCTGAAGAACAGTGCTCCCAGCAAGCGAGAGATTGCCCAGC
TCAAGAACCAGCTGGAGGAGTCAGAGTTCACCTGTGCGGCAGCCGTGAAAGCACGGAAAGCAATGGAGGTGGAGATCGAAGACCTGCACC
TGCAGATTGATGACATCGCCAAAGCCAAGACAGCGCTGGAGGAGCAGCTGAGCCGCCTTCAGCGTGAGAAGAATGAGATCCAGAACCGGC
TGGAGGAAGATCAGGAAGACATGAACGAATTGATGAAGAAGCACAAGGCTGCCGTGGCTCAGGCTTCCCGGGACCTGGCTCAGATAAATG
ATCTCCAAGCTCAGCTAGAAGAAGCCAACAAAGAGAAGCAGGAGCTGCAGGAGAAGCTACAAGCCCTCCAGAGCCAGGTGGAGTTCCTGG
AGCAGTCCATGGTGGACAAGTCCCTGGTGAGCAGGCAGGAAGCTAAGATACGGGAGCTGGAGACACGCCTGGAGTTTGAAAGGACGCAAG
TGAAACGGCTGGAGAGCCTGGCTAGCCGTCTCAAGGAAAACATGGAGAAGCTGACTGAGGAGCGGGATCAGCGCATTGCAGCCGAGAACC
GGGAGAAGGAACAGAACAAGCGGCTACAGAGGCAGCTCCGGGACACCAAGGAGGAGATGGGCGAGCTTGCCAGGAAGGAGGCCGAGGCGA
GCCGCAAGAAGCACGAACTGGAGATGGATCTAGAAAGCCTGGAGGCTGCTAACCAGAGCCTGCAGGCTGACCTAAAGTTGGCATTCAAGC
GCATCGGGGACCTGCAGGCTGCCATTGAGGATGAGATGGAGAGTGATGAGAATGAGGACCTCATCAACAGTTTGCAGGACATGGTGACAA
AGTATCAGAAAAGAAAGAATAAACTTGAGGGAGACTCTGATGTGGACTCGGAGCTGGAGGACCGTGTTGACGGGGTCAAGTCCTGGTTGT
CAAAAAACAAGGGACCTTCCAAGGCAGCTTCTGATGATGGCAGCTTAAAGAGTTCCAGTGAGAAGCGCCACCTTCAAGTGAACGTCACCA
ACCCAGTACAGTGCAGCCTGCACGGGAAGAAGTGCACCGTCTCCGTGGAGACGCGGCTCAACCAGCCCCAGCCCGACTTCACCAAGAATC
GCTCGGGCTTCATCCTCAGCGTGCCCGGGAACTGACGCCCCGCGGAGGCCTGGCCCGGAGCCCGGCCACACTCCGAGTCCTGGGTCCCAG
TCCAGCTGCTGCCTCCCAACCCATGCCCGCTAGAAACCTGCTGCGAGGGCCCCTCCCAGAGGAGCCCCGCCCCTGTAAGATTTCCTTCCT
GGTTTTCTGCCTTTGGTATCATCTTCCTCTGTCCTTACTGTCCACGGTCCCTGTTCAATAAGCCAAAGACCCTGGTGCCCCGCCCAGACC
CCTGGGCTGACGTCCAGACCAATCTCACCCCAGAGGCAACTGGATGGTGCCTTTAGTTGGTGCGGATGCCCCGTGGCCAGGTCAAGTCAG
AGCACCTGGACAGGTGTCCTCCCTGCTGCTGACCCTGCAGAGGGAAGGGGTGGGGATGCAGGACCCCACTCTGCGGGAGCCCCATAGCCA
CCTCTCTTGCCCAAGGTGAGCCAGCCCTGGGGACCCAGCTCAGGGAGGCTCTGCTCAGAGTTCGGCGGACCCACCCCAACCCAACTCCCA
GCCGCCAGCCAAAGCCACTGGGTGAGCAGAGTCACCCACAGGGCCAGCCCCTCAGCCAGGAGCCAGTGGCAGGAGCGGAACAGCCCATCC
AGCAGAGTGAGTCCATCCTTCCCAGGTTCTCCCCTGGGAGACTCCCTTTGCCACCAAGGCCCCCACCAGGGCCTCTGACCACCGCTCTGG
AGAGGACAGTGTGGCATGCTCCAAGGATCATCTTACTTAACTCGCAGCCTGTGGCTGTGGTCCTCTTATAGATACTTTCACCGTTTGCAG
GGTTGCTAATCAGATACCTGCTGTCACCACACTTGGGTCAGGAACCCTAATGAGAACGGGGAGCTGCCAGGGTGAGGGCAGCCCTCAGGG
TCGGCCGCTTTCCCTCTGGACCACCTCCCGCTGCGTTTCCTACTCAGAGAAACAGCAAGGGCGGGGTCAAGACACGGGATGACGGGAAGC
AGGAAGCGGGGCAGCAGCACAGCGTGGGGTCCTGGCACTGCAGGCCAGGCCAGGATGCCCACCCCGCCCTCTACACGGCCCCTTGGGGCC
TGCGCCCGTGAAACTGGTGCCAGGGAGCACTGCCAGCTTGCCAGTTTCTGCCCAGCAAAAGCACGTATGCTTCAGGGGCCTTCTGAGACC
ACCTTCCCCACTGAGCCCCAGCTGCTGAGAAGGCCTTGAGGGAAGTAGAGGCTGGGAGCAAATGCCCCATGCGGTGAGAGGATGAGGGGA
GCCTACGCCTCAGGCATGTGGTGAGAGGATGAGGGGGAGGGAGCCAACGCCTCAGGTGGAGTGGGCAGAGGTGCAAGAGAGGGATGTACT
GAAGCTTCTTCCCGTCCTGCCACAGACACTTCTCCTGCCTTCCCACCCTGACCCGGCAGAACCCACCAAGTGCCTGTGTGCAGCCTCCTG
TGCCTCACCCAGGGCCTGACCCCAGAGTGGTCCCAACAACCCGGTCTCATGCCCACTCCCCATCCCTGCTTCCCAAAAATTGCACTGTGT
GCAGTTTGCAACAAAGAATCCCGCTGGCATCCTGTCCTTGGGAACCCTTTCTCATTCTCCAAGCCTGGTCAGCTGCCTGCACAGGCAGAG
GTGCCCTCAGCCCAGATTAGCAACACTCATAGTTTTGCCAATTACCAGTAGACACTAGTGGAACCATCTAACTGGAACTTCCTCTCTCCT
TCCACTTATTTCCTCAAACTTGTTGCTTTACACTAGACACATGCAAATGTATGTTTTAAACACACCAAAACAGATCATGCCAAATGAGTT
GCCTGTCAAAGGCTGGAGGGCAGGAGGAGGGCCTGGGTTTGGGTTCTTTCCTCCCAGCCTTTGGATGGTGCCTTGGGCCCCTTAGCCCCA
GCGCCAGGGCCTCCCAGCTGAGGCCACAGGACAAGCACTTTTTTATGATGTACTAAAAGCCACAGTATGTGGCAACTGCAAAAGGATCAG
GAATTTAGGGTATGATCTCGGTCACGTGTCCCGGGCGCTGAGGGGAAAGGAAGCGGGCATGATTGTAGACAATGAGGGGGTTCTCTTGAT
GTAATGAAATGCAATTTTATGGTTTGGTGCAAAAACTCCTATTTTCCAGTAAATTAACTTTATTTCTAAAGCATATTTTGATTTGCCATC

>56594_56594_1_MYO18A-MYO1D_MYO18A_chr17_27409334_ENST00000354329_MYO1D_chr17_30821933_ENST00000394649_length(amino acids)=2058AA_BP=2004
MFNLMKKDKDKDGGRKEKKEKKEKKERMSAAELRSLEEMSLRRGFFNLNRSSKRESKTRLEISNPIPIKVASGSDLHLTDIDSDSNRGSV
ILDSGHLSTASSSDDLKGEEGSFRGSVLQRAAKFGSLAKQNSQMIVKRFSFSQRSRDESASETSTPSEHSAAPSPQVEVRTLEGQLVQHP
GPGIPRPGHRSRAPELVTKKFPVDLRLPPVVPLPPPTLRELELQRRPTGDFGFSLRRTTMLDRGPEGQACRRVVHFAEPGAGTKDLALGL
VPGDRLVEINGHNVESKSRDEIVEMIRQSGDSVRLKVQPIPELSELSRSWLRSGEGPRREPSDAKTEEQIAAEEAWNETEKVWLVHRDGF
SLASQLKSEELNLPEGKVRVKLDHDGAILDVDEDDVEKANAPSCDRLEDLASLVYLNESSVLHTLRQRYGASLLHTYAGPSLLVLGPRGA
PAVYSEKVMHMFKGCRREDMAPHIYAVAQTAYRAMLMSRQDQSIILLGSSGSGKTTSCQHLVQYLATIAGISGNKVFSVEKWQALYTLLE
AFGNSPTIINGNATRFSQILSLDFDQAGQVASASIQTMLLEKLRVARRPASEATFNVFYYLLACGDGTLRTELHLNHLAENNVFGIVPLA
KPEEKQKAAQQFSKLQAAMKVLGISPDEQKACWFILAAIYHLGAAGATKVHSTAGRKQFARHEWAQKAAYLLGCSLEELSSAIFKHQHKG
GTLQRSTSFRQGPEESGLGDGTGPKLSALECLEGMAAGLYSELFTLLVSLVNRALKSSQHSLCSMMIVDTPGFQNPEQGGSARGASFEEL
CHNYTQDRLQRLFHERTFVQELERYKEENIELAFDDLEPPTDDSVAAVDQASHQSLVRSLARTDEARGLLWLLEEEALVPGASEDTLLER
LFSYYGPQEGDKKGQSPLLHSSKPHHFLLGHSHGTNWVEYNVTGWLNYTKQNPATQNAPRLLQDSQKKIISNLFLGRAGSATVLSGSIAG
LEGGSQLALRRATSMRKTFTTGMAAVKKKSLCIQMKLQVDALIDTIKKSKLHFVHCFLPVAEGWAGEPRSASSRRVSSSSELDLPSGDHC
EAGLLQLDVPLLRTQLRGSRLLDAMRMYRQGYPDHMVFSEFRRRFDVLAPHLTKKHGRNYIVVDERRAVEELLECLDLEKSSCCMGLSRV
FFRAGTLARLEEQRDEQTSRNLTLFQAACRGYLARQHFKKRKIQDLAIRCVQKNIKKNKGVKDWPWWKLFTTVRPLIEVQLSEEQIRNKD
EEIQQLRSKLEKAEKERNELRLNSDRLESRISELTSELTDERNTGESASQLLDAETAERLRAEKEMKELQTQYDALKKQMEVMEMEVMEA
RLIRAAEINGEVDDDDAGGEWRLKYERAVREVDFTKKRLQQEFEDKLEVEQQNKRQLERRLGDLQADSEESQRALQQLKKKCQRLTAELQ
DTKLHLEGQQVRNHELEKKQRRFDSELSQAHEEAQREKLQREKLQREKDMLLAEAFSLKQQLEEKDMDIAGFTQKVVSLEAELQDISSQE
SKDEASLAKVKKQLRDLEAKVKDQEEELDEQAGTIQMLEQAKLRLEMEMERMRQTHSKEMESRDEEVEEARQSCQKKLKQMEVQLEEEYE
DKQKVLREKRELEGKLATLSDQVNRRDFESEKRLRKDLKRTKALLADAQLMLDHLKNSAPSKREIAQLKNQLEESEFTCAAAVKARKAME
VEIEDLHLQIDDIAKAKTALEEQLSRLQREKNEIQNRLEEDQEDMNELMKKHKAAVAQASRDLAQINDLQAQLEEANKEKQELQEKLQAL
QSQVEFLEQSMVDKSLVSRQEAKIRELETRLEFERTQVKRLESLASRLKENMEKLTEERDQRIAAENREKEQNKRLQRQLRDTKEEMGEL
ARKEAEASRKKHELEMDLESLEAANQSLQADLKLAFKRIGDLQAAIEDEMESDENEDLINSLQDMVTKYQKRKNKLEGDSDVDSELEDRV

--------------------------------------------------------------
>56594_56594_2_MYO18A-MYO1D_MYO18A_chr17_27409334_ENST00000527372_MYO1D_chr17_30821933_ENST00000394649_length(transcript)=8508nt_BP=6201nt
AGCTGCGCCGCGCTGCGCTCTGCTCCATCCCTGACCGGGCCGAGGCTGCTGGATGCCGCGTCTCCGCTTCTGCTGCCTGCCGGGCGGGCT
CCGGTGGCCGCAGCAAAGTGGGGCACCAAGGCCCTGTGCTAAGCACTCATAATCCTCTGGGGGTGCTACCCCTACAAACAGCACCCCCAC
CATGTTTAACCTAATGAAGAAAGACAAGGACAAAGATGGCGGGCGGAAGGAGAAGAAGGAGAAAAAGGAGAAAAAGGAGCGGATGTCAGC
GGCAGAGCTTCGGAGCCTGGAGGAGATGAGCCTGCGACGTGGCTTCTTCAACCTGAACCGCTCCTCCAAGCGTGAATCCAAGACGCGCCT
GGAAATCTCCAACCCCATCCCCATCAAGGTGGCCAGCGGCTCTGACCTGCACCTGACTGACATTGACTCCGATAGTAACCGGGGCAGCGT
CATCCTGGACTCGGGCCACCTAAGTACAGCCAGCTCCAGCGATGACCTCAAGGGTGAGGAGGGTAGCTTCCGTGGCTCGGTGCTGCAGCG
GGCAGCCAAGTTCGGCTCACTGGCCAAGCAGAACTCACAGATGATTGTCAAGCGCTTTTCCTTCTCCCAGCGTAGCCGGGATGAGAGCGC
CTCAGAAACCTCGACGCCCTCAGAGCACTCTGCCGCCCCCTCGCCACAGGTGGAGGTGAGGACTCTAGAGGGACAGCTGGTGCAGCATCC
TGGCCCAGGCATCCCTCGACCAGGGCACCGATCCCGAGCCCCTGAGCTAGTGACTAAAAAGTTCCCAGTCGACCTGCGCCTGCCCCCCGT
GGTGCCCCTGCCCCCACCTACCCTCCGGGAGCTGGAGCTGCAACGACGGCCCACTGGAGACTTTGGCTTCTCCCTGCGGCGCACAACCAT
GCTGGATCGGGGCCCCGAGGGCCAGGCCTGTCGGCGTGTGGTCCACTTTGCTGAGCCTGGTGCAGGCACCAAGGACCTGGCCCTGGGGCT
GGTGCCAGGAGATCGACTGGTGGAGATTAATGGGCACAATGTGGAGAGCAAGTCCAGGGATGAGATTGTGGAGATGATCCGGCAGTCAGG
GGACAGCGTGCGGCTCAAGGTGCAGCCCATTCCAGAGCTCAGCGAGCTCAGCAGGAGCTGGCTGCGGAGCGGCGAGGGACCTCGCAGGGA
GCCATCCGATGCGAAAACAGAAGAACAGATTGCAGCAGAAGAGGCCTGGAATGAGACGGAGAAGGTGTGGCTGGTCCATAGGGACGGCTT
CTCACTGGCCAGTCAACTCAAATCTGAGGAGCTCAACTTGCCTGAGGGGAAGGTGCGTGTGAAGCTGGACCACGATGGGGCCATCCTGGA
TGTGGATGAGGATGACGTTGAGAAGGCTAATGCTCCCTCCTGCGACCGTCTGGAGGATCTGGCCTCACTGGTGTACCTCAATGAGTCCAG
CGTCCTGCACACCTTGCGCCAGCGCTATGGCGCTAGCCTGCTGCACACGTATGCTGGCCCCAGCCTGCTGGTTCTTGGCCCCCGTGGGGC
CCCTGCTGTGTACTCTGAGAAGGTGATGCACATGTTCAAGGGTTGTCGGCGGGAGGACATGGCACCCCACATCTATGCAGTGGCCCAGAC
CGCATACAGGGCGATGCTGATGAGCCGTCAGGATCAGTCAATCATCCTCCTGGGCAGTAGTGGCAGTGGCAAGACCACCAGCTGCCAGCA
TCTGGTGCAGTACCTGGCCACCATCGCGGGCATCAGCGGGAACAAGGTGTTTTCTGTGGAGAAGTGGCAGGCTCTGTACACCCTCCTGGA
AGCCTTTGGGAACAGCCCCACCATCATTAATGGCAATGCCACCCGCTTCTCCCAGATCCTCTCCCTGGACTTTGACCAAGCTGGCCAGGT
GGCCTCAGCCTCCATTCAGACAATGCTTCTGGAGAAGCTGCGTGTGGCTCGGCGCCCAGCCAGTGAAGCCACATTCAACGTCTTCTACTA
CCTGCTGGCCTGTGGGGATGGCACCCTCAGGACAGAGCTCCACCTCAACCACTTGGCAGAGAACAATGTGTTTGGGATTGTGCCACTGGC
CAAGCCTGAGGAAAAGCAGAAGGCAGCTCAGCAGTTTAGTAAGCTGCAGGCGGCCATGAAGGTGCTGGGCATCTCCCCCGATGAACAGAA
GGCCTGCTGGTTCATTCTGGCTGCCATCTACCACCTGGGGGCTGCGGGAGCCACCAAAGAAGCTGCTGAAGCTGGGCGCAAGCAGTTTGC
CCGCCATGAGTGGGCCCAGAAGGCTGCGTACCTACTGGGCTGCAGCCTGGAGGAGCTGTCCTCAGCCATCTTCAAGCACCAGCACAAGGG
TGGCACCCTGCAGCGCTCCACCTCCTTCCGCCAGGGCCCCGAGGAGAGTGGCCTGGGAGATGGGACAGGCCCGAAACTGAGTGCACTGGA
GTGCCTTGAGGGCATGGCGGCCGGCCTCTACAGCGAGCTCTTCACCCTTCTCGTCTCCCTGGTGAATAGGGCTCTCAAGTCCAGCCAGCA
CTCACTCTGCTCCATGATGATTGTCGACACCCCGGGCTTCCAGAACCCTGAGCAGGGTGGGTCAGCCCGCGGAGCCTCCTTTGAGGAGCT
GTGCCACAACTACACCCAAGACCGGCTGCAGAGGCTCTTCCACGAGCGCACCTTCGTGCAGGAGTTGGAAAGATACAAGGAGGAGAACAT
CGAGCTGGCGTTTGACGACTTGGAACCCCCGACGGATGACTCTGTGGCTGCTGTGGACCAGGCCTCCCATCAGTCCCTGGTCCGCTCGCT
GGCCCGCACAGACGAGGCGAGGGGCCTGCTCTGGCTATTGGAAGAGGAGGCTCTGGTGCCAGGGGCCAGTGAGGACACCCTCCTGGAGCG
CCTTTTCTCCTATTATGGCCCCCAGGAAGGTGACAAAAAAGGCCAAAGCCCCCTTCTGCACAGCAGCAAACCACACCACTTTCTCCTGGG
CCACAGCCATGGCACCAACTGGGTAGAGTACAATGTGACTGGCTGGCTGAACTACACCAAGCAGAACCCAGCCACCCAGAATGCCCCCCG
GCTCCTGCAGGACTCCCAGAAAAAAATCATCAGCAACCTGTTTCTGGGCCGCGCAGGCAGTGCCACGGTGCTCTCTGGCTCCATCGCGGG
CCTGGAGGGCGGCTCGCAGCTGGCACTGCGCCGGGCCACCAGCATGCGGAAAACCTTTACCACAGGCATGGCGGCTGTCAAAAAGAAGTC
ACTGTGCATCCAGATGAAGCTACAGGTGGACGCCCTCATCGACACCATCAAGAAGTCAAAGCTGCATTTTGTGCACTGCTTCCTGCCTGT
AGCTGAGGGCTGGGCTGGGGAGCCCCGTTCCGCCTCCTCCCGCCGAGTCAGCAGCAGCAGTGAGCTGGACCTGCCCTCGGGAGACCACTG
CGAGGCTGGGCTCCTGCAGCTCGACGTGCCCCTGCTCCGCACCCAGCTCCGCGGCTCCCGCCTGCTCGATGCCATGCGCATGTACCGCCA
AGGTTACCCTGACCACATGGTGTTTTCCGAGTTCCGCCGCCGCTTTGATGTCCTGGCCCCGCACCTGACCAAGAAACACGGGCGTAACTA
CATCGTGGTGGATGAAAGGCGGGCAGTGGAGGAGCTGCTGGAGTGCTTGGATCTGGAGAAGAGCAGCTGCTGCATGGGCCTGAGCCGGGT
GTTCTTCCGGGCGGGCACCTTGGCACGGCTGGAGGAGCAGCGGGATGAACAAACCAGCAGGAACCTAACCCTGTTCCAAGCAGCCTGCAG
GGGCTACCTGGCCCGCCAGCACTTCAAGAAGAGAAAGATCCAGGACCTGGCCATTCGCTGTGTACAGAAGAACATCAAGAAGAACAAAGG
GGTGAAGGACTGGCCCTGGTGGAAGCTTTTTACCACAGTGAGGCCCCTCATCGAAGTACAGCTGTCAGAGGAGCAGATCCGGAACAAAGA
CGAGGAGATCCAGCAGCTGCGGAGCAAGCTCGAGAAGGCGGAGAAGGAGAGGAACGAGCTGCGGCTCAACAGTGACCGGCTGGAGAGCCG
GATCTCAGAGCTGACATCGGAGCTGACAGATGAGCGTAACACAGGAGAGTCCGCCTCCCAGCTGCTGGACGCGGAGACAGCAGAGAGGCT
CCGGGCTGAGAAGGAGATGAAGGAACTGCAGACCCAGTACGATGCACTGAAGAAGCAGATGGAGGTTATGGAAATGGAGGTGATGGAGGC
CCGTCTCATCCGGGCAGCGGAGATCAACGGGGAAGTGGATGATGATGATGCAGGTGGCGAGTGGCGGCTGAAGTATGAGCGGGCTGTGCG
GGAGGTGGACTTCACCAAGAAACGGCTCCAGCAGGAGTTTGAGGACAAGCTGGAGGTGGAGCAGCAGAACAAGAGGCAGCTGGAACGGCG
GCTCGGGGACCTGCAGGCAGATAGTGAGGAGAGTCAGCGGGCTCTGCAGCAGCTCAAGAAGAAGTGCCAGCGACTGACGGCTGAGCTGCA
AGACACCAAGCTGCACCTGGAGGGCCAGCAGGTCCGCAACCACGAACTGGAGAAGAAGCAGAGGAGGTTTGACAGTGAGCTCTCGCAGGC
GCATGAGGAGGCCCAGCGGGAGAAGCTGCAGCGGGAGAAGCTGCAGCGGGAGAAGGACATGCTCCTCGCTGAGGCTTTCAGCCTGAAGCA
GCAACTAGAGGAAAAAGACATGGACATTGCAGGGTTCACCCAGAAGGTTGTGTCTCTAGAGGCAGAGCTCCAGGACATTTCTTCCCAAGA
GTCCAAGGATGAGGCTTCTCTGGCCAAGGTCAAGAAACAGCTCCGGGACCTGGAGGCCAAAGTCAAGGATCAGGAAGAAGAGCTGGATGA
GCAGGCAGGGACCATCCAGATGCTGGAACAGGCCAAGCTGCGTCTGGAGATGGAGATGGAGCGGATGAGACAGACCCATTCTAAGGAGAT
GGAGAGTCGGGATGAGGAGGTGGAGGAGGCCCGGCAGTCGTGTCAGAAGAAGTTAAAACAGATGGAGGTGCAGCTAGAGGAAGAGTATGA
GGACAAGCAGAAGGTTCTGCGAGAGAAGCGGGAGCTGGAGGGCAAGCTCGCCACCCTCAGCGACCAGGTGAACCGGCGGGACTTTGAGTC
AGAGAAGCGGCTGCGGAAGGACCTGAAGCGCACCAAGGCCCTGCTGGCAGATGCCCAGCTCATGCTGGACCACCTGAAGAACAGTGCTCC
CAGCAAGCGAGAGATTGCCCAGCTCAAGAACCAGCTGGAGGAGTCAGAGTTCACCTGTGCGGCAGCCGTGAAAGCACGGAAAGCAATGGA
GGTGGAGATCGAAGACCTGCACCTGCAGATTGATGACATCGCCAAAGCCAAGACAGCGCTGGAGGAGCAGCTGAGCCGCCTTCAGCGTGA
GAAGAATGAGATCCAGAACCGGCTGGAGGAAGATCAGGAAGACATGAACGAATTGATGAAGAAGCACAAGGCTGCCGTGGCTCAGGCTTC
CCGGGACCTGGCTCAGATAAATGATCTCCAAGCTCAGCTAGAAGAAGCCAACAAAGAGAAGCAGGAGCTGCAGGAGAAGCTACAAGCCCT
CCAGAGCCAGGTGGAGTTCCTGGAGCAGTCCATGGTGGACAAGTCCCTGGTGAGCAGGCAGGAAGCTAAGATACGGGAGCTGGAGACACG
CCTGGAGTTTGAAAGGACGCAAGTGAAACGGCTGGAGAGCCTGGCTAGCCGTCTCAAGGAAAACATGGAGAAGCTGACTGAGGAGCGGGA
TCAGCGCATTGCAGCCGAGAACCGGGAGAAGGAACAGAACAAGCGGCTACAGAGGCAGCTCCGGGACACCAAGGAGGAGATGGGCGAGCT
TGCCAGGAAGGAGGCCGAGGCGAGCCGCAAGAAGCACGAACTGGAGATGGATCTAGAAAGCCTGGAGGCTGCTAACCAGAGCCTGCAGGC
TGACCTAAAGTTGGCATTCAAGCGCATCGGGGACCTGCAGGCTGCCATTGAGGATGAGATGGAGAGTGATGAGAATGAGGACCTCATCAA
CAGTTTGCAGGACATGGTGACAAAGTATCAGAAAAGAAAGAATAAACTTGAGGGAGACTCTGATGTGGACTCGGAGCTGGAGGACCGTGT
TGACGGGGTCAAGTCCTGGTTGTCAAAAAACAAGGGACCTTCCAAGGCAGCTTCTGATGATGGCAGCTTAAAGAGTTCCAGTGAGAAGCG
CCACCTTCAAGTGAACGTCACCAACCCAGTACAGTGCAGCCTGCACGGGAAGAAGTGCACCGTCTCCGTGGAGACGCGGCTCAACCAGCC
CCAGCCCGACTTCACCAAGAATCGCTCGGGCTTCATCCTCAGCGTGCCCGGGAACTGACGCCCCGCGGAGGCCTGGCCCGGAGCCCGGCC
ACACTCCGAGTCCTGGGTCCCAGTCCAGCTGCTGCCTCCCAACCCATGCCCGCTAGAAACCTGCTGCGAGGGCCCCTCCCAGAGGAGCCC
CGCCCCTGTAAGATTTCCTTCCTGGTTTTCTGCCTTTGGTATCATCTTCCTCTGTCCTTACTGTCCACGGTCCCTGTTCAATAAGCCAAA
GACCCTGGTGCCCCGCCCAGACCCCTGGGCTGACGTCCAGACCAATCTCACCCCAGAGGCAACTGGATGGTGCCTTTAGTTGGTGCGGAT
GCCCCGTGGCCAGGTCAAGTCAGAGCACCTGGACAGGTGTCCTCCCTGCTGCTGACCCTGCAGAGGGAAGGGGTGGGGATGCAGGACCCC
ACTCTGCGGGAGCCCCATAGCCACCTCTCTTGCCCAAGGTGAGCCAGCCCTGGGGACCCAGCTCAGGGAGGCTCTGCTCAGAGTTCGGCG
GACCCACCCCAACCCAACTCCCAGCCGCCAGCCAAAGCCACTGGGTGAGCAGAGTCACCCACAGGGCCAGCCCCTCAGCCAGGAGCCAGT
GGCAGGAGCGGAACAGCCCATCCAGCAGAGTGAGTCCATCCTTCCCAGGTTCTCCCCTGGGAGACTCCCTTTGCCACCAAGGCCCCCACC
AGGGCCTCTGACCACCGCTCTGGAGAGGACAGTGTGGCATGCTCCAAGGATCATCTTACTTAACTCGCAGCCTGTGGCTGTGGTCCTCTT
ATAGATACTTTCACCGTTTGCAGGGTTGCTAATCAGATACCTGCTGTCACCACACTTGGGTCAGGAACCCTAATGAGAACGGGGAGCTGC
CAGGGTGAGGGCAGCCCTCAGGGTCGGCCGCTTTCCCTCTGGACCACCTCCCGCTGCGTTTCCTACTCAGAGAAACAGCAAGGGCGGGGT
CAAGACACGGGATGACGGGAAGCAGGAAGCGGGGCAGCAGCACAGCGTGGGGTCCTGGCACTGCAGGCCAGGCCAGGATGCCCACCCCGC
CCTCTACACGGCCCCTTGGGGCCTGCGCCCGTGAAACTGGTGCCAGGGAGCACTGCCAGCTTGCCAGTTTCTGCCCAGCAAAAGCACGTA
TGCTTCAGGGGCCTTCTGAGACCACCTTCCCCACTGAGCCCCAGCTGCTGAGAAGGCCTTGAGGGAAGTAGAGGCTGGGAGCAAATGCCC
CATGCGGTGAGAGGATGAGGGGAGCCTACGCCTCAGGCATGTGGTGAGAGGATGAGGGGGAGGGAGCCAACGCCTCAGGTGGAGTGGGCA
GAGGTGCAAGAGAGGGATGTACTGAAGCTTCTTCCCGTCCTGCCACAGACACTTCTCCTGCCTTCCCACCCTGACCCGGCAGAACCCACC
AAGTGCCTGTGTGCAGCCTCCTGTGCCTCACCCAGGGCCTGACCCCAGAGTGGTCCCAACAACCCGGTCTCATGCCCACTCCCCATCCCT
GCTTCCCAAAAATTGCACTGTGTGCAGTTTGCAACAAAGAATCCCGCTGGCATCCTGTCCTTGGGAACCCTTTCTCATTCTCCAAGCCTG
GTCAGCTGCCTGCACAGGCAGAGGTGCCCTCAGCCCAGATTAGCAACACTCATAGTTTTGCCAATTACCAGTAGACACTAGTGGAACCAT
CTAACTGGAACTTCCTCTCTCCTTCCACTTATTTCCTCAAACTTGTTGCTTTACACTAGACACATGCAAATGTATGTTTTAAACACACCA
AAACAGATCATGCCAAATGAGTTGCCTGTCAAAGGCTGGAGGGCAGGAGGAGGGCCTGGGTTTGGGTTCTTTCCTCCCAGCCTTTGGATG
GTGCCTTGGGCCCCTTAGCCCCAGCGCCAGGGCCTCCCAGCTGAGGCCACAGGACAAGCACTTTTTTATGATGTACTAAAAGCCACAGTA
TGTGGCAACTGCAAAAGGATCAGGAATTTAGGGTATGATCTCGGTCACGTGTCCCGGGCGCTGAGGGGAAAGGAAGCGGGCATGATTGTA
GACAATGAGGGGGTTCTCTTGATGTAATGAAATGCAATTTTATGGTTTGGTGCAAAAACTCCTATTTTCCAGTAAATTAACTTTATTTCT

>56594_56594_2_MYO18A-MYO1D_MYO18A_chr17_27409334_ENST00000527372_MYO1D_chr17_30821933_ENST00000394649_length(amino acids)=2058AA_BP=2004
MFNLMKKDKDKDGGRKEKKEKKEKKERMSAAELRSLEEMSLRRGFFNLNRSSKRESKTRLEISNPIPIKVASGSDLHLTDIDSDSNRGSV
ILDSGHLSTASSSDDLKGEEGSFRGSVLQRAAKFGSLAKQNSQMIVKRFSFSQRSRDESASETSTPSEHSAAPSPQVEVRTLEGQLVQHP
GPGIPRPGHRSRAPELVTKKFPVDLRLPPVVPLPPPTLRELELQRRPTGDFGFSLRRTTMLDRGPEGQACRRVVHFAEPGAGTKDLALGL
VPGDRLVEINGHNVESKSRDEIVEMIRQSGDSVRLKVQPIPELSELSRSWLRSGEGPRREPSDAKTEEQIAAEEAWNETEKVWLVHRDGF
SLASQLKSEELNLPEGKVRVKLDHDGAILDVDEDDVEKANAPSCDRLEDLASLVYLNESSVLHTLRQRYGASLLHTYAGPSLLVLGPRGA
PAVYSEKVMHMFKGCRREDMAPHIYAVAQTAYRAMLMSRQDQSIILLGSSGSGKTTSCQHLVQYLATIAGISGNKVFSVEKWQALYTLLE
AFGNSPTIINGNATRFSQILSLDFDQAGQVASASIQTMLLEKLRVARRPASEATFNVFYYLLACGDGTLRTELHLNHLAENNVFGIVPLA
KPEEKQKAAQQFSKLQAAMKVLGISPDEQKACWFILAAIYHLGAAGATKEAAEAGRKQFARHEWAQKAAYLLGCSLEELSSAIFKHQHKG
GTLQRSTSFRQGPEESGLGDGTGPKLSALECLEGMAAGLYSELFTLLVSLVNRALKSSQHSLCSMMIVDTPGFQNPEQGGSARGASFEEL
CHNYTQDRLQRLFHERTFVQELERYKEENIELAFDDLEPPTDDSVAAVDQASHQSLVRSLARTDEARGLLWLLEEEALVPGASEDTLLER
LFSYYGPQEGDKKGQSPLLHSSKPHHFLLGHSHGTNWVEYNVTGWLNYTKQNPATQNAPRLLQDSQKKIISNLFLGRAGSATVLSGSIAG
LEGGSQLALRRATSMRKTFTTGMAAVKKKSLCIQMKLQVDALIDTIKKSKLHFVHCFLPVAEGWAGEPRSASSRRVSSSSELDLPSGDHC
EAGLLQLDVPLLRTQLRGSRLLDAMRMYRQGYPDHMVFSEFRRRFDVLAPHLTKKHGRNYIVVDERRAVEELLECLDLEKSSCCMGLSRV
FFRAGTLARLEEQRDEQTSRNLTLFQAACRGYLARQHFKKRKIQDLAIRCVQKNIKKNKGVKDWPWWKLFTTVRPLIEVQLSEEQIRNKD
EEIQQLRSKLEKAEKERNELRLNSDRLESRISELTSELTDERNTGESASQLLDAETAERLRAEKEMKELQTQYDALKKQMEVMEMEVMEA
RLIRAAEINGEVDDDDAGGEWRLKYERAVREVDFTKKRLQQEFEDKLEVEQQNKRQLERRLGDLQADSEESQRALQQLKKKCQRLTAELQ
DTKLHLEGQQVRNHELEKKQRRFDSELSQAHEEAQREKLQREKLQREKDMLLAEAFSLKQQLEEKDMDIAGFTQKVVSLEAELQDISSQE
SKDEASLAKVKKQLRDLEAKVKDQEEELDEQAGTIQMLEQAKLRLEMEMERMRQTHSKEMESRDEEVEEARQSCQKKLKQMEVQLEEEYE
DKQKVLREKRELEGKLATLSDQVNRRDFESEKRLRKDLKRTKALLADAQLMLDHLKNSAPSKREIAQLKNQLEESEFTCAAAVKARKAME
VEIEDLHLQIDDIAKAKTALEEQLSRLQREKNEIQNRLEEDQEDMNELMKKHKAAVAQASRDLAQINDLQAQLEEANKEKQELQEKLQAL
QSQVEFLEQSMVDKSLVSRQEAKIRELETRLEFERTQVKRLESLASRLKENMEKLTEERDQRIAAENREKEQNKRLQRQLRDTKEEMGEL
ARKEAEASRKKHELEMDLESLEAANQSLQADLKLAFKRIGDLQAAIEDEMESDENEDLINSLQDMVTKYQKRKNKLEGDSDVDSELEDRV

--------------------------------------------------------------
>56594_56594_3_MYO18A-MYO1D_MYO18A_chr17_27409334_ENST00000531253_MYO1D_chr17_30821933_ENST00000394649_length(transcript)=8415nt_BP=6108nt
CTGGATGCCGCGTCTCCGCTTCTGCTGCCTGCCGGGCGGGCTCCGGTGGCCGCAGCAAAGTGGGGCACCAAGGCCCTGTGCTAAGCACTC
ATAATCCTCTGGGGGTGCTACCCCTACAAACAGCACCCCCACCATGTTTAACCTAATGAAGAAAGACAAGGACAAAGATGGCGGGCGGAA
GGAGAAGAAGGAGAAAAAGGAGAAAAAGGAGCGGATGTCAGCGGCAGAGCTTCGGAGCCTGGAGGAGATGAGCCTGCGACGTGGCTTCTT
CAACCTGAACCGCTCCTCCAAGCGTGAATCCAAGACGCGCCTGGAAATCTCCAACCCCATCCCCATCAAGGTGGCCAGCGGCTCTGACCT
GCACCTGACTGACATTGACTCCGATAGTAACCGGGGCAGCGTCATCCTGGACTCGGGCCACCTAAGTACAGCCAGCTCCAGCGATGACCT
CAAGGGTGAGGAGGGTAGCTTCCGTGGCTCGGTGCTGCAGCGGGCAGCCAAGTTCGGCTCACTGGCCAAGCAGAACTCACAGATGATTGT
CAAGCGCTTTTCCTTCTCCCAGCGTAGCCGGGATGAGAGCGCCTCAGAAACCTCGACGCCCTCAGAGCACTCTGCCGCCCCCTCGCCACA
GGTGGAGGTGAGGACTCTAGAGGGACAGCTGGTGCAGCATCCTGGCCCAGGCATCCCTCGACCAGGGCACCGATCCCGAGCCCCTGAGCT
AGTGACTAAAAAGTTCCCAGTCGACCTGCGCCTGCCCCCCGTGGTGCCCCTGCCCCCACCTACCCTCCGGGAGCTGGAGCTGCAACGACG
GCCCACTGGAGACTTTGGCTTCTCCCTGCGGCGCACAACCATGCTGGATCGGGGCCCCGAGGGCCAGGCCTGTCGGCGTGTGGTCCACTT
TGCTGAGCCTGGTGCAGGCACCAAGGACCTGGCCCTGGGGCTGGTGCCAGGAGATCGACTGGTGGAGATTAATGGGCACAATGTGGAGAG
CAAGTCCAGGGATGAGATTGTGGAGATGATCCGGCAGTCAGGGGACAGCGTGCGGCTCAAGGTGCAGCCCATTCCAGAGCTCAGCGAGCT
CAGCAGGAGCTGGCTGCGGAGCGGCGAGGGACCTCGCAGGGAGCCATCCGATGCGAAAACAGAAGAACAGATTGCAGCAGAAGAGGCCTG
GAATGAGACGGAGAAGGTGTGGCTGGTCCATAGGGACGGCTTCTCACTGGCCAGTCAACTCAAATCTGAGGAGCTCAACTTGCCTGAGGG
GAAGGTGCGTGTGAAGCTGGACCACGATGGGGCCATCCTGGATGTGGATGAGGATGACGTTGAGAAGGCTAATGCTCCCTCCTGCGACCG
TCTGGAGGATCTGGCCTCACTGGTGTACCTCAATGAGTCCAGCGTCCTGCACACCTTGCGCCAGCGCTATGGCGCTAGCCTGCTGCACAC
GTATGCTGGCCCCAGCCTGCTGGTTCTTGGCCCCCGTGGGGCCCCTGCTGTGTACTCTGAGAAGGTGATGCACATGTTCAAGGGTTGTCG
GCGGGAGGACATGGCACCCCACATCTATGCAGTGGCCCAGACCGCATACAGGGCGATGCTGATGAGCCGTCAGGATCAGTCAATCATCCT
CCTGGGCAGTAGTGGCAGTGGCAAGACCACCAGCTGCCAGCATCTGGTGCAGTACCTGGCCACCATCGCGGGCATCAGCGGGAACAAGGT
GTTTTCTGTGGAGAAGTGGCAGGCTCTGTACACCCTCCTGGAAGCCTTTGGGAACAGCCCCACCATCATTAATGGCAATGCCACCCGCTT
CTCCCAGATCCTCTCCCTGGACTTTGACCAAGCTGGCCAGGTGGCCTCAGCCTCCATTCAGACAATGCTTCTGGAGAAGCTGCGTGTGGC
TCGGCGCCCAGCCAGTGAAGCCACATTCAACGTCTTCTACTACCTGCTGGCCTGTGGGGATGGCACCCTCAGGACAGAGCTCCACCTCAA
CCACTTGGCAGAGAACAATGTGTTTGGGATTGTGCCACTGGCCAAGCCTGAGGAAAAGCAGAAGGCAGCTCAGCAGTTTAGTAAGCTGCA
GGCGGCCATGAAGGTGCTGGGCATCTCCCCCGATGAACAGAAGGCCTGCTGGTTCATTCTGGCTGCCATCTACCACCTGGGGGCTGCGGG
AGCCACCAAAGAAGCTGCTGAAGCTGGGCGCAAGCAGTTTGCCCGCCATGAGTGGGCCCAGAAGGCTGCGTACCTACTGGGCTGCAGCCT
GGAGGAGCTGTCCTCAGCCATCTTCAAGCACCAGCACAAGGGTGGCACCCTGCAGCGCTCCACCTCCTTCCGCCAGGGCCCCGAGGAGAG
TGGCCTGGGAGATGGGACAGGCCCGAAACTGAGTGCACTGGAGTGCCTTGAGGGCATGGCGGCCGGCCTCTACAGCGAGCTCTTCACCCT
TCTCGTCTCCCTGGTGAATAGGGCTCTCAAGTCCAGCCAGCACTCACTCTGCTCCATGATGATTGTCGACACCCCGGGCTTCCAGAACCC
TGAGCAGGGTGGGTCAGCCCGCGGAGCCTCCTTTGAGGAGCTGTGCCACAACTACACCCAAGACCGGCTGCAGAGGCTCTTCCACGAGCG
CACCTTCGTGCAGGAGTTGGAAAGATACAAGGAGGAGAACATCGAGCTGGCGTTTGACGACTTGGAACCCCCGACGGATGACTCTGTGGC
TGCTGTGGACCAGGCCTCCCATCAGTCCCTGGTCCGCTCGCTGGCCCGCACAGACGAGGCGAGGGGCCTGCTCTGGCTATTGGAAGAGGA
GGCTCTGGTGCCAGGGGCCAGTGAGGACACCCTCCTGGAGCGCCTTTTCTCCTATTATGGCCCCCAGGAAGGTGACAAAAAAGGCCAAAG
CCCCCTTCTGCACAGCAGCAAACCACACCACTTTCTCCTGGGCCACAGCCATGGCACCAACTGGGTAGAGTACAATGTGACTGGCTGGCT
GAACTACACCAAGCAGAACCCAGCCACCCAGAATGCCCCCCGGCTCCTGCAGGACTCCCAGAAAAAAATCATCAGCAACCTGTTTCTGGG
CCGCGCAGGCAGTGCCACGGTGCTCTCTGGCTCCATCGCGGGCCTGGAGGGCGGCTCGCAGCTGGCACTGCGCCGGGCCACCAGCATGCG
GAAAACCTTTACCACAGGCATGGCGGCTGTCAAAAAGAAGTCACTGTGCATCCAGATGAAGCTACAGGTGGACGCCCTCATCGACACCAT
CAAGAAGTCAAAGCTGCATTTTGTGCACTGCTTCCTGCCTGTAGCTGAGGGCTGGGCTGGGGAGCCCCGTTCCGCCTCCTCCCGCCGAGT
CAGCAGCAGCAGTGAGCTGGACCTGCCCTCGGGAGACCACTGCGAGGCTGGGCTCCTGCAGCTCGACGTGCCCCTGCTCCGCACCCAGCT
CCGCGGCTCCCGCCTGCTCGATGCCATGCGCATGTACCGCCAAGGTTACCCTGACCACATGGTGTTTTCCGAGTTCCGCCGCCGCTTTGA
TGTCCTGGCCCCGCACCTGACCAAGAAACACGGGCGTAACTACATCGTGGTGGATGAAAGGCGGGCAGTGGAGGAGCTGCTGGAGTGCTT
GGATCTGGAGAAGAGCAGCTGCTGCATGGGCCTGAGCCGGGTGTTCTTCCGGGCGGGCACCTTGGCACGGCTGGAGGAGCAGCGGGATGA
ACAAACCAGCAGGAACCTAACCCTGTTCCAAGCAGCCTGCAGGGGCTACCTGGCCCGCCAGCACTTCAAGAAGAGAAAGATCCAGGACCT
GGCCATTCGCTGTGTACAGAAGAACATCAAGAAGAACAAAGGGGTGAAGGACTGGCCCTGGTGGAAGCTTTTTACCACAGTGAGGCCCCT
CATCGAAGTACAGCTGTCAGAGGAGCAGATCCGGAACAAAGACGAGGAGATCCAGCAGCTGCGGAGCAAGCTCGAGAAGGCGGAGAAGGA
GAGGAACGAGCTGCGGCTCAACAGTGACCGGCTGGAGAGCCGGATCTCAGAGCTGACATCGGAGCTGACAGATGAGCGTAACACAGGAGA
GTCCGCCTCCCAGCTGCTGGACGCGGAGACAGCAGAGAGGCTCCGGGCTGAGAAGGAGATGAAGGAACTGCAGACCCAGTACGATGCACT
GAAGAAGCAGATGGAGGTTATGGAAATGGAGGTGATGGAGGCCCGTCTCATCCGGGCAGCGGAGATCAACGGGGAAGTGGATGATGATGA
TGCAGGTGGCGAGTGGCGGCTGAAGTATGAGCGGGCTGTGCGGGAGGTGGACTTCACCAAGAAACGGCTCCAGCAGGAGTTTGAGGACAA
GCTGGAGGTGGAGCAGCAGAACAAGAGGCAGCTGGAACGGCGGCTCGGGGACCTGCAGGCAGATAGTGAGGAGAGTCAGCGGGCTCTGCA
GCAGCTCAAGAAGAAGTGCCAGCGACTGACGGCTGAGCTGCAAGACACCAAGCTGCACCTGGAGGGCCAGCAGGTCCGCAACCACGAACT
GGAGAAGAAGCAGAGGAGGTTTGACAGTGAGCTCTCGCAGGCGCATGAGGAGGCCCAGCGGGAGAAGCTGCAGCGGGAGAAGCTGCAGCG
GGAGAAGGACATGCTCCTCGCTGAGGCTTTCAGCCTGAAGCAGCAACTAGAGGAAAAAGACATGGACATTGCAGGGTTCACCCAGAAGGT
TGTGTCTCTAGAGGCAGAGCTCCAGGACATTTCTTCCCAAGAGTCCAAGGATGAGGCTTCTCTGGCCAAGGTCAAGAAACAGCTCCGGGA
CCTGGAGGCCAAAGTCAAGGATCAGGAAGAAGAGCTGGATGAGCAGGCAGGGACCATCCAGATGCTGGAACAGGCCAAGCTGCGTCTGGA
GATGGAGATGGAGCGGATGAGACAGACCCATTCTAAGGAGATGGAGAGTCGGGATGAGGAGGTGGAGGAGGCCCGGCAGTCGTGTCAGAA
GAAGTTAAAACAGATGGAGGTGCAGCTAGAGGAAGAGTATGAGGACAAGCAGAAGGTTCTGCGAGAGAAGCGGGAGCTGGAGGGCAAGCT
CGCCACCCTCAGCGACCAGGTGAACCGGCGGGACTTTGAGTCAGAGAAGCGGCTGCGGAAGGACCTGAAGCGCACCAAGGCCCTGCTGGC
AGATGCCCAGCTCATGCTGGACCACCTGAAGAACAGTGCTCCCAGCAAGCGAGAGATTGCCCAGCTCAAGAACCAGCTGGAGGAGTCAGA
GTTCACCTGTGCGGCAGCCGTGAAAGCACGGAAAGCAATGGAGGTGGAGATCGAAGACCTGCACCTGCAGATTGATGACATCGCCAAAGC
CAAGACAGCGCTGGAGGAGCAGCTGAGCCGCCTTCAGCGTGAGAAGAATGAGATCCAGAACCGGCTGGAGGAAGATCAGGAAGACATGAA
CGAATTGATGAAGAAGCACAAGGCTGCCGTGGCTCAGGCTTCCCGGGACCTGGCTCAGATAAATGATCTCCAAGCTCAGCTAGAAGAAGC
CAACAAAGAGAAGCAGGAGCTGCAGGAGAAGCTACAAGCCCTCCAGAGCCAGGTGGAGTTCCTGGAGCAGTCCATGGTGGACAAGTCCCT
GGTGAGCAGGCAGGAAGCTAAGATACGGGAGCTGGAGACACGCCTGGAGTTTGAAAGGACGCAAGTGAAACGGCTGGAGAGCCTGGCTAG
CCGTCTCAAGGAAAACATGGAGAAGCTGACTGAGGAGCGGGATCAGCGCATTGCAGCCGAGAACCGGGAGAAGGAACAGAACAAGCGGCT
ACAGAGGCAGCTCCGGGACACCAAGGAGGAGATGGGCGAGCTTGCCAGGAAGGAGGCCGAGGCGAGCCGCAAGAAGCACGAACTGGAGAT
GGATCTAGAAAGCCTGGAGGCTGCTAACCAGAGCCTGCAGGCTGACCTAAAGTTGGCATTCAAGCGCATCGGGGACCTGCAGGCTGCCAT
TGAGGATGAGATGGAGAGTGATGAGAATGAGGACCTCATCAACAGTGAGGGAGACTCTGATGTGGACTCGGAGCTGGAGGACCGTGTTGA
CGGGGTCAAGTCCTGGTTGTCAAAAAACAAGGGACCTTCCAAGGCAGCTTCTGATGATGGCAGCTTAAAGAGTTCCAGTGAGAAGCGCCA
CCTTCAAGTGAACGTCACCAACCCAGTACAGTGCAGCCTGCACGGGAAGAAGTGCACCGTCTCCGTGGAGACGCGGCTCAACCAGCCCCA
GCCCGACTTCACCAAGAATCGCTCGGGCTTCATCCTCAGCGTGCCCGGGAACTGACGCCCCGCGGAGGCCTGGCCCGGAGCCCGGCCACA
CTCCGAGTCCTGGGTCCCAGTCCAGCTGCTGCCTCCCAACCCATGCCCGCTAGAAACCTGCTGCGAGGGCCCCTCCCAGAGGAGCCCCGC
CCCTGTAAGATTTCCTTCCTGGTTTTCTGCCTTTGGTATCATCTTCCTCTGTCCTTACTGTCCACGGTCCCTGTTCAATAAGCCAAAGAC
CCTGGTGCCCCGCCCAGACCCCTGGGCTGACGTCCAGACCAATCTCACCCCAGAGGCAACTGGATGGTGCCTTTAGTTGGTGCGGATGCC
CCGTGGCCAGGTCAAGTCAGAGCACCTGGACAGGTGTCCTCCCTGCTGCTGACCCTGCAGAGGGAAGGGGTGGGGATGCAGGACCCCACT
CTGCGGGAGCCCCATAGCCACCTCTCTTGCCCAAGGTGAGCCAGCCCTGGGGACCCAGCTCAGGGAGGCTCTGCTCAGAGTTCGGCGGAC
CCACCCCAACCCAACTCCCAGCCGCCAGCCAAAGCCACTGGGTGAGCAGAGTCACCCACAGGGCCAGCCCCTCAGCCAGGAGCCAGTGGC
AGGAGCGGAACAGCCCATCCAGCAGAGTGAGTCCATCCTTCCCAGGTTCTCCCCTGGGAGACTCCCTTTGCCACCAAGGCCCCCACCAGG
GCCTCTGACCACCGCTCTGGAGAGGACAGTGTGGCATGCTCCAAGGATCATCTTACTTAACTCGCAGCCTGTGGCTGTGGTCCTCTTATA
GATACTTTCACCGTTTGCAGGGTTGCTAATCAGATACCTGCTGTCACCACACTTGGGTCAGGAACCCTAATGAGAACGGGGAGCTGCCAG
GGTGAGGGCAGCCCTCAGGGTCGGCCGCTTTCCCTCTGGACCACCTCCCGCTGCGTTTCCTACTCAGAGAAACAGCAAGGGCGGGGTCAA
GACACGGGATGACGGGAAGCAGGAAGCGGGGCAGCAGCACAGCGTGGGGTCCTGGCACTGCAGGCCAGGCCAGGATGCCCACCCCGCCCT
CTACACGGCCCCTTGGGGCCTGCGCCCGTGAAACTGGTGCCAGGGAGCACTGCCAGCTTGCCAGTTTCTGCCCAGCAAAAGCACGTATGC
TTCAGGGGCCTTCTGAGACCACCTTCCCCACTGAGCCCCAGCTGCTGAGAAGGCCTTGAGGGAAGTAGAGGCTGGGAGCAAATGCCCCAT
GCGGTGAGAGGATGAGGGGAGCCTACGCCTCAGGCATGTGGTGAGAGGATGAGGGGGAGGGAGCCAACGCCTCAGGTGGAGTGGGCAGAG
GTGCAAGAGAGGGATGTACTGAAGCTTCTTCCCGTCCTGCCACAGACACTTCTCCTGCCTTCCCACCCTGACCCGGCAGAACCCACCAAG
TGCCTGTGTGCAGCCTCCTGTGCCTCACCCAGGGCCTGACCCCAGAGTGGTCCCAACAACCCGGTCTCATGCCCACTCCCCATCCCTGCT
TCCCAAAAATTGCACTGTGTGCAGTTTGCAACAAAGAATCCCGCTGGCATCCTGTCCTTGGGAACCCTTTCTCATTCTCCAAGCCTGGTC
AGCTGCCTGCACAGGCAGAGGTGCCCTCAGCCCAGATTAGCAACACTCATAGTTTTGCCAATTACCAGTAGACACTAGTGGAACCATCTA
ACTGGAACTTCCTCTCTCCTTCCACTTATTTCCTCAAACTTGTTGCTTTACACTAGACACATGCAAATGTATGTTTTAAACACACCAAAA
CAGATCATGCCAAATGAGTTGCCTGTCAAAGGCTGGAGGGCAGGAGGAGGGCCTGGGTTTGGGTTCTTTCCTCCCAGCCTTTGGATGGTG
CCTTGGGCCCCTTAGCCCCAGCGCCAGGGCCTCCCAGCTGAGGCCACAGGACAAGCACTTTTTTATGATGTACTAAAAGCCACAGTATGT
GGCAACTGCAAAAGGATCAGGAATTTAGGGTATGATCTCGGTCACGTGTCCCGGGCGCTGAGGGGAAAGGAAGCGGGCATGATTGTAGAC
AATGAGGGGGTTCTCTTGATGTAATGAAATGCAATTTTATGGTTTGGTGCAAAAACTCCTATTTTCCAGTAAATTAACTTTATTTCTAAA

>56594_56594_3_MYO18A-MYO1D_MYO18A_chr17_27409334_ENST00000531253_MYO1D_chr17_30821933_ENST00000394649_length(amino acids)=2043AA_BP=1989
MFNLMKKDKDKDGGRKEKKEKKEKKERMSAAELRSLEEMSLRRGFFNLNRSSKRESKTRLEISNPIPIKVASGSDLHLTDIDSDSNRGSV
ILDSGHLSTASSSDDLKGEEGSFRGSVLQRAAKFGSLAKQNSQMIVKRFSFSQRSRDESASETSTPSEHSAAPSPQVEVRTLEGQLVQHP
GPGIPRPGHRSRAPELVTKKFPVDLRLPPVVPLPPPTLRELELQRRPTGDFGFSLRRTTMLDRGPEGQACRRVVHFAEPGAGTKDLALGL
VPGDRLVEINGHNVESKSRDEIVEMIRQSGDSVRLKVQPIPELSELSRSWLRSGEGPRREPSDAKTEEQIAAEEAWNETEKVWLVHRDGF
SLASQLKSEELNLPEGKVRVKLDHDGAILDVDEDDVEKANAPSCDRLEDLASLVYLNESSVLHTLRQRYGASLLHTYAGPSLLVLGPRGA
PAVYSEKVMHMFKGCRREDMAPHIYAVAQTAYRAMLMSRQDQSIILLGSSGSGKTTSCQHLVQYLATIAGISGNKVFSVEKWQALYTLLE
AFGNSPTIINGNATRFSQILSLDFDQAGQVASASIQTMLLEKLRVARRPASEATFNVFYYLLACGDGTLRTELHLNHLAENNVFGIVPLA
KPEEKQKAAQQFSKLQAAMKVLGISPDEQKACWFILAAIYHLGAAGATKEAAEAGRKQFARHEWAQKAAYLLGCSLEELSSAIFKHQHKG
GTLQRSTSFRQGPEESGLGDGTGPKLSALECLEGMAAGLYSELFTLLVSLVNRALKSSQHSLCSMMIVDTPGFQNPEQGGSARGASFEEL
CHNYTQDRLQRLFHERTFVQELERYKEENIELAFDDLEPPTDDSVAAVDQASHQSLVRSLARTDEARGLLWLLEEEALVPGASEDTLLER
LFSYYGPQEGDKKGQSPLLHSSKPHHFLLGHSHGTNWVEYNVTGWLNYTKQNPATQNAPRLLQDSQKKIISNLFLGRAGSATVLSGSIAG
LEGGSQLALRRATSMRKTFTTGMAAVKKKSLCIQMKLQVDALIDTIKKSKLHFVHCFLPVAEGWAGEPRSASSRRVSSSSELDLPSGDHC
EAGLLQLDVPLLRTQLRGSRLLDAMRMYRQGYPDHMVFSEFRRRFDVLAPHLTKKHGRNYIVVDERRAVEELLECLDLEKSSCCMGLSRV
FFRAGTLARLEEQRDEQTSRNLTLFQAACRGYLARQHFKKRKIQDLAIRCVQKNIKKNKGVKDWPWWKLFTTVRPLIEVQLSEEQIRNKD
EEIQQLRSKLEKAEKERNELRLNSDRLESRISELTSELTDERNTGESASQLLDAETAERLRAEKEMKELQTQYDALKKQMEVMEMEVMEA
RLIRAAEINGEVDDDDAGGEWRLKYERAVREVDFTKKRLQQEFEDKLEVEQQNKRQLERRLGDLQADSEESQRALQQLKKKCQRLTAELQ
DTKLHLEGQQVRNHELEKKQRRFDSELSQAHEEAQREKLQREKLQREKDMLLAEAFSLKQQLEEKDMDIAGFTQKVVSLEAELQDISSQE
SKDEASLAKVKKQLRDLEAKVKDQEEELDEQAGTIQMLEQAKLRLEMEMERMRQTHSKEMESRDEEVEEARQSCQKKLKQMEVQLEEEYE
DKQKVLREKRELEGKLATLSDQVNRRDFESEKRLRKDLKRTKALLADAQLMLDHLKNSAPSKREIAQLKNQLEESEFTCAAAVKARKAME
VEIEDLHLQIDDIAKAKTALEEQLSRLQREKNEIQNRLEEDQEDMNELMKKHKAAVAQASRDLAQINDLQAQLEEANKEKQELQEKLQAL
QSQVEFLEQSMVDKSLVSRQEAKIRELETRLEFERTQVKRLESLASRLKENMEKLTEERDQRIAAENREKEQNKRLQRQLRDTKEEMGEL
ARKEAEASRKKHELEMDLESLEAANQSLQADLKLAFKRIGDLQAAIEDEMESDENEDLINSEGDSDVDSELEDRVDGVKSWLSKNKGPSK

--------------------------------------------------------------
>56594_56594_4_MYO18A-MYO1D_MYO18A_chr17_27409334_ENST00000533112_MYO1D_chr17_30821933_ENST00000394649_length(transcript)=8433nt_BP=6126nt
GCAGGGAGTCACCCGGCGCTGCGGAGCTCAGCACAGCCGGCCGGGAGGAGGCTCCCCCTGGAGCACGGGGCCAGGCCAGGTGCTGGCTAC
CCCTCCGGCCGCTGCTACAACCCTTGGCGAGGGGCAGAGCGCGGGGAGAGAGCCGGGGTCCCGGGGCTGGAGGAAACGGCCGCTCAGGGA
GCAGCAAAGTGGGGCACCAAGGCCCTGTGCTAAGCACTCATAATCCTCTGGGGGTGCTACCCCTACAAACAGCACCCCCACCATGTTTAA
CCTAATGAAGAAAGACAAGGACAAAGATGGCGGGCGGAAGGAGAAGAAGGAGAAAAAGGAGAAAAAGGAGCGGATGTCAGCGGCAGAGCT
TCGGAGCCTGGAGGAGATGAGCCTGCGACGTGGCTTCTTCAACCTGAACCGCTCCTCCAAGCGTGAATCCAAGACGCGCCTGGAAATCTC
CAACCCCATCCCCATCAAGGTGGCCAGCGGCTCTGACCTGCACCTGACTGACATTGACTCCGATAGTAACCGGGGCAGCGTCATCCTGGA
CTCGGGCCACCTAAGTACAGCCAGCTCCAGCGATGACCTCAAGGGTGAGGAGGGTAGCTTCCGTGGCTCGGTGCTGCAGCGGGCAGCCAA
GTTCGGCTCACTGGCCAAGCAGAACTCACAGATGATTGTCAAGCGCTTTTCCTTCTCCCAGCGTAGCCGGGATGAGAGCGCCTCAGAAAC
CTCGACGCCCTCAGAGCACTCTGCCGCCCCCTCGCCACAGGTGGAGGTGAGGACTCTAGAGGGACAGCTGGTGCAGCATCCTGGCCCAGG
CATCCCTCGACCAGGGCACCGATCCCGAGCCCCTGAGCTAGTGACTAAAAAGTTCCCAGTCGACCTGCGCCTGCCCCCCGTGGTGCCCCT
GCCCCCACCTACCCTCCGGGAGCTGGAGCTGCAACGACGGCCCACTGGAGACTTTGGCTTCTCCCTGCGGCGCACAACCATGCTGGATCG
GGGCCCCGAGGGCCAGGCCTGTCGGCGTGTGGTCCACTTTGCTGAGCCTGGTGCAGGCACCAAGGACCTGGCCCTGGGGCTGGTGCCAGG
AGATCGACTGGTGGAGATTAATGGGCACAATGTGGAGAGCAAGTCCAGGGATGAGATTGTGGAGATGATCCGGCAGTCAGGGGACAGCGT
GCGGCTCAAGGTGCAGCCCATTCCAGAGCTCAGCGAGCTCAGCAGGAGCTGGCTGCGGAGCGGCGAGGGACCTCGCAGGGAGCCATCCGA
TGCGAAAACAGAAGAACAGATTGCAGCAGAAGAGGCCTGGAATGAGACGGAGAAGGTGTGGCTGGTCCATAGGGACGGCTTCTCACTGGC
CAGTCAACTCAAATCTGAGGAGCTCAACTTGCCTGAGGGGAAGGTGCGTGTGAAGCTGGACCACGATGGGGCCATCCTGGATGTGGATGA
GGATGACGTTGAGAAGGCTAATGCTCCCTCCTGCGACCGTCTGGAGGATCTGGCCTCACTGGTGTACCTCAATGAGTCCAGCGTCCTGCA
CACCTTGCGCCAGCGCTATGGCGCTAGCCTGCTGCACACGTATGCTGGCCCCAGCCTGCTGGTTCTTGGCCCCCGTGGGGCCCCTGCTGT
GTACTCTGAGAAGGTGATGCACATGTTCAAGGGTTGTCGGCGGGAGGACATGGCACCCCACATCTATGCAGTGGCCCAGACCGCATACAG
GGCGATGCTGATGAGCCGTCAGGATCAGTCAATCATCCTCCTGGGCAGTAGTGGCAGTGGCAAGACCACCAGCTGCCAGCATCTGGTGCA
GTACCTGGCCACCATCGCGGGCATCAGCGGGAACAAGGTGTTTTCTGTGGAGAAGTGGCAGGCTCTGTACACCCTCCTGGAAGCCTTTGG
GAACAGCCCCACCATCATTAATGGCAATGCCACCCGCTTCTCCCAGATCCTCTCCCTGGACTTTGACCAAGCTGGCCAGGTGGCCTCAGC
CTCCATTCAGACAATGCTTCTGGAGAAGCTGCGTGTGGCTCGGCGCCCAGCCAGTGAAGCCACATTCAACGTCTTCTACTACCTGCTGGC
CTGTGGGGATGGCACCCTCAGGACAGAGCTCCACCTCAACCACTTGGCAGAGAACAATGTGTTTGGGATTGTGCCACTGGCCAAGCCTGA
GGAAAAGCAGAAGGCAGCTCAGCAGTTTAGTAAGCTGCAGGCGGCCATGAAGGTGCTGGGCATCTCCCCCGATGAACAGAAGGCCTGCTG
GTTCATTCTGGCTGCCATCTACCACCTGGGGGCTGCGGGAGCCACCAAAGAAGCTGCTGAAGCTGGGCGCAAGCAGTTTGCCCGCCATGA
GTGGGCCCAGAAGGCTGCGTACCTACTGGGCTGCAGCCTGGAGGAGCTGTCCTCAGCCATCTTCAAGCACCAGCACAAGGGTGGCACCCT
GCAGCGCTCCACCTCCTTCCGCCAGGGCCCCGAGGAGAGTGGCCTGGGAGATGGGACAGGCCCGAAACTGAGTGCACTGGAGTGCCTTGA
GGGCATGGCGGCCGGCCTCTACAGCGAGCTCTTCACCCTTCTCGTCTCCCTGGTGAATAGGGCTCTCAAGTCCAGCCAGCACTCACTCTG
CTCCATGATGATTGTCGACACCCCGGGCTTCCAGAACCCTGAGCAGGGTGGGTCAGCCCGCGGAGCCTCCTTTGAGGAGCTGTGCCACAA
CTACACCCAAGACCGGCTGCAGAGGCTCTTCCACGAGCGCACCTTCGTGCAGGAGTTGGAAAGATACAAGGAGGAGAACATCGAGCTGGC
GTTTGACGACTTGGAACCCCCGACGGATGACTCTGTGGCTGCTGTGGACCAGGCCTCCCATCAGTCCCTGGTCCGCTCGCTGGCCCGCAC
AGACGAGGCGAGGGGCCTGCTCTGGCTATTGGAAGAGGAGGCTCTGGTGCCAGGGGCCAGTGAGGACACCCTCCTGGAGCGCCTTTTCTC
CTATTATGGCCCCCAGGAAGGTGACAAAAAAGGCCAAAGCCCCCTTCTGCACAGCAGCAAACCACACCACTTTCTCCTGGGCCACAGCCA
TGGCACCAACTGGGTAGAGTACAATGTGACTGGCTGGCTGAACTACACCAAGCAGAACCCAGCCACCCAGAATGCCCCCCGGCTCCTGCA
GGACTCCCAGAAAAAAATCATCAGCAACCTGTTTCTGGGCCGCGCAGGCAGTGCCACGGTGCTCTCTGGCTCCATCGCGGGCCTGGAGGG
CGGCTCGCAGCTGGCACTGCGCCGGGCCACCAGCATGCGGAAAACCTTTACCACAGGCATGGCGGCTGTCAAAAAGAAGTCACTGTGCAT
CCAGATGAAGCTACAGGTGGACGCCCTCATCGACACCATCAAGAAGTCAAAGCTGCATTTTGTGCACTGCTTCCTGCCTGTAGCTGAGGG
CTGGGCTGGGGAGCCCCGTTCCGCCTCCTCCCGCCGAGTCAGCAGCAGCAGTGAGCTGGACCTGCCCTCGGGAGACCACTGCGAGGCTGG
GCTCCTGCAGCTCGACGTGCCCCTGCTCCGCACCCAGCTCCGCGGCTCCCGCCTGCTCGATGCCATGCGCATGTACCGCCAAGGTTACCC
TGACCACATGGTGTTTTCCGAGTTCCGCCGCCGCTTTGATGTCCTGGCCCCGCACCTGACCAAGAAACACGGGCGTAACTACATCGTGGT
GGATGAAAGGCGGGCAGTGGAGGAGCTGCTGGAGTGCTTGGATCTGGAGAAGAGCAGCTGCTGCATGGGCCTGAGCCGGGTGTTCTTCCG
GGCGGGCACCTTGGCACGGCTGGAGGAGCAGCGGGATGAACAAACCAGCAGGAACCTAACCCTGTTCCAAGCAGCCTGCAGGGGCTACCT
GGCCCGCCAGCACTTCAAGAAGAGAAAGATCCAGGACCTGGCCATTCGCTGTGTACAGAAGAACATCAAGAAGAACAAAGGGGTGAAGGA
CTGGCCCTGGTGGAAGCTTTTTACCACAGTGAGGCCCCTCATCGAAGTACAGCTGTCAGAGGAGCAGATCCGGAACAAAGACGAGGAGAT
CCAGCAGCTGCGGAGCAAGCTCGAGAAGGCGGAGAAGGAGAGGAACGAGCTGCGGCTCAACAGTGACCGGCTGGAGAGCCGGATCTCAGA
GCTGACATCGGAGCTGACAGATGAGCGTAACACAGGAGAGTCCGCCTCCCAGCTGCTGGACGCGGAGACAGCAGAGAGGCTCCGGGCTGA
GAAGGAGATGAAGGAACTGCAGACCCAGTACGATGCACTGAAGAAGCAGATGGAGGTTATGGAAATGGAGGTGATGGAGGCCCGTCTCAT
CCGGGCAGCGGAGATCAACGGGGAAGTGGATGATGATGATGCAGGTGGCGAGTGGCGGCTGAAGTATGAGCGGGCTGTGCGGGAGGTGGA
CTTCACCAAGAAACGGCTCCAGCAGGAGTTTGAGGACAAGCTGGAGGTGGAGCAGCAGAACAAGAGGCAGCTGGAACGGCGGCTCGGGGA
CCTGCAGGCAGATAGTGAGGAGAGTCAGCGGGCTCTGCAGCAGCTCAAGAAGAAGTGCCAGCGACTGACGGCTGAGCTGCAAGACACCAA
GCTGCACCTGGAGGGCCAGCAGGTCCGCAACCACGAACTGGAGAAGAAGCAGAGGAGGTTTGACAGTGAGCTCTCGCAGGCGCATGAGGA
GGCCCAGCGGGAGAAGCTGCAGCGGGAGAAGCTGCAGCGGGAGAAGGACATGCTCCTCGCTGAGGCTTTCAGCCTGAAGCAGCAACTAGA
GGAAAAAGACATGGACATTGCAGGGTTCACCCAGAAGGTTGTGTCTCTAGAGGCAGAGCTCCAGGACATTTCTTCCCAAGAGTCCAAGGA
TGAGGCTTCTCTGGCCAAGGTCAAGAAACAGCTCCGGGACCTGGAGGCCAAAGTCAAGGATCAGGAAGAAGAGCTGGATGAGCAGGCAGG
GACCATCCAGATGCTGGAACAGTTAAAACAGATGGAGGTGCAGCTAGAGGAAGAGTATGAGGACAAGCAGAAGGTTCTGCGAGAGAAGCG
GGAGCTGGAGGGCAAGCTCGCCACCCTCAGCGACCAGGTGAACCGGCGGGACTTTGAGTCAGAGAAGCGGCTGCGGAAGGACCTGAAGCG
CACCAAGGCCCTGCTGGCAGATGCCCAGCTCATGCTGGACCACCTGAAGAACAGTGCTCCCAGCAAGCGAGAGATTGCCCAGCTCAAGAA
CCAGCTGGAGGAGTCAGAGTTCACCTGTGCGGCAGCCGTGAAAGCACGGAAAGCAATGGAGGTGGAGATCGAAGACCTGCACCTGCAGAT
TGATGACATCGCCAAAGCCAAGACAGCGCTGGAGGAGCAGCTGAGCCGCCTTCAGCGTGAGAAGAATGAGATCCAGAACCGGCTGGAGGA
AGATCAGGAAGACATGAACGAATTGATGAAGAAGCACAAGGCTGCCGTGGCTCAGGCTTCCCGGGACCTGGCTCAGATAAATGATCTCCA
AGCTCAGCTAGAAGAAGCCAACAAAGAGAAGCAGGAGCTGCAGGAGAAGCTACAAGCCCTCCAGAGCCAGGTGGAGTTCCTGGAGCAGTC
CATGGTGGACAAGTCCCTGGTGAGCAGGCAGGAAGCTAAGATACGGGAGCTGGAGACACGCCTGGAGTTTGAAAGGACGCAAGTGAAACG
GCTGGAGAGCCTGGCTAGCCGTCTCAAGGAAAACATGGAGAAGCTGACTGAGGAGCGGGATCAGCGCATTGCAGCCGAGAACCGGGAGAA
GGAACAGAACAAGCGGCTACAGAGGCAGCTCCGGGACACCAAGGAGGAGATGGGCGAGCTTGCCAGGAAGGAGGCCGAGGCGAGCCGCAA
GAAGCACGAACTGGAGATGGATCTAGAAAGCCTGGAGGCTGCTAACCAGAGCCTGCAGGCTGACCTAAAGTTGGCATTCAAGCGCATCGG
GGACCTGCAGGCTGCCATTGAGGATGAGATGGAGAGTGATGAGAATGAGGACCTCATCAACAGTGAGGGAGACTCTGATGTGGACTCGGA
GCTGGAGGACCGTGTTGACGGGGTCAAGTCCTGGTTGTCAAAAAACAAGGGACCTTCCAAGGCAGCTTCTGATGATGGCAGCTTAAAGAG
TTCCAGTGAGAAGCGCCACCTTCAAGTGAACGTCACCAACCCAGTACAGTGCAGCCTGCACGGGAAGAAGTGCACCGTCTCCGTGGAGAC
GCGGCTCAACCAGCCCCAGCCCGACTTCACCAAGAATCGCTCGGGCTTCATCCTCAGCGTGCCCGGGAACTGACGCCCCGCGGAGGCCTG
GCCCGGAGCCCGGCCACACTCCGAGTCCTGGGTCCCAGTCCAGCTGCTGCCTCCCAACCCATGCCCGCTAGAAACCTGCTGCGAGGGCCC
CTCCCAGAGGAGCCCCGCCCCTGTAAGATTTCCTTCCTGGTTTTCTGCCTTTGGTATCATCTTCCTCTGTCCTTACTGTCCACGGTCCCT
GTTCAATAAGCCAAAGACCCTGGTGCCCCGCCCAGACCCCTGGGCTGACGTCCAGACCAATCTCACCCCAGAGGCAACTGGATGGTGCCT
TTAGTTGGTGCGGATGCCCCGTGGCCAGGTCAAGTCAGAGCACCTGGACAGGTGTCCTCCCTGCTGCTGACCCTGCAGAGGGAAGGGGTG
GGGATGCAGGACCCCACTCTGCGGGAGCCCCATAGCCACCTCTCTTGCCCAAGGTGAGCCAGCCCTGGGGACCCAGCTCAGGGAGGCTCT
GCTCAGAGTTCGGCGGACCCACCCCAACCCAACTCCCAGCCGCCAGCCAAAGCCACTGGGTGAGCAGAGTCACCCACAGGGCCAGCCCCT
CAGCCAGGAGCCAGTGGCAGGAGCGGAACAGCCCATCCAGCAGAGTGAGTCCATCCTTCCCAGGTTCTCCCCTGGGAGACTCCCTTTGCC
ACCAAGGCCCCCACCAGGGCCTCTGACCACCGCTCTGGAGAGGACAGTGTGGCATGCTCCAAGGATCATCTTACTTAACTCGCAGCCTGT
GGCTGTGGTCCTCTTATAGATACTTTCACCGTTTGCAGGGTTGCTAATCAGATACCTGCTGTCACCACACTTGGGTCAGGAACCCTAATG
AGAACGGGGAGCTGCCAGGGTGAGGGCAGCCCTCAGGGTCGGCCGCTTTCCCTCTGGACCACCTCCCGCTGCGTTTCCTACTCAGAGAAA
CAGCAAGGGCGGGGTCAAGACACGGGATGACGGGAAGCAGGAAGCGGGGCAGCAGCACAGCGTGGGGTCCTGGCACTGCAGGCCAGGCCA
GGATGCCCACCCCGCCCTCTACACGGCCCCTTGGGGCCTGCGCCCGTGAAACTGGTGCCAGGGAGCACTGCCAGCTTGCCAGTTTCTGCC
CAGCAAAAGCACGTATGCTTCAGGGGCCTTCTGAGACCACCTTCCCCACTGAGCCCCAGCTGCTGAGAAGGCCTTGAGGGAAGTAGAGGC
TGGGAGCAAATGCCCCATGCGGTGAGAGGATGAGGGGAGCCTACGCCTCAGGCATGTGGTGAGAGGATGAGGGGGAGGGAGCCAACGCCT
CAGGTGGAGTGGGCAGAGGTGCAAGAGAGGGATGTACTGAAGCTTCTTCCCGTCCTGCCACAGACACTTCTCCTGCCTTCCCACCCTGAC
CCGGCAGAACCCACCAAGTGCCTGTGTGCAGCCTCCTGTGCCTCACCCAGGGCCTGACCCCAGAGTGGTCCCAACAACCCGGTCTCATGC
CCACTCCCCATCCCTGCTTCCCAAAAATTGCACTGTGTGCAGTTTGCAACAAAGAATCCCGCTGGCATCCTGTCCTTGGGAACCCTTTCT
CATTCTCCAAGCCTGGTCAGCTGCCTGCACAGGCAGAGGTGCCCTCAGCCCAGATTAGCAACACTCATAGTTTTGCCAATTACCAGTAGA
CACTAGTGGAACCATCTAACTGGAACTTCCTCTCTCCTTCCACTTATTTCCTCAAACTTGTTGCTTTACACTAGACACATGCAAATGTAT
GTTTTAAACACACCAAAACAGATCATGCCAAATGAGTTGCCTGTCAAAGGCTGGAGGGCAGGAGGAGGGCCTGGGTTTGGGTTCTTTCCT
CCCAGCCTTTGGATGGTGCCTTGGGCCCCTTAGCCCCAGCGCCAGGGCCTCCCAGCTGAGGCCACAGGACAAGCACTTTTTTATGATGTA
CTAAAAGCCACAGTATGTGGCAACTGCAAAAGGATCAGGAATTTAGGGTATGATCTCGGTCACGTGTCCCGGGCGCTGAGGGGAAAGGAA
GCGGGCATGATTGTAGACAATGAGGGGGTTCTCTTGATGTAATGAAATGCAATTTTATGGTTTGGTGCAAAAACTCCTATTTTCCAGTAA

>56594_56594_4_MYO18A-MYO1D_MYO18A_chr17_27409334_ENST00000533112_MYO1D_chr17_30821933_ENST00000394649_length(amino acids)=2006AA_BP=1952
MFNLMKKDKDKDGGRKEKKEKKEKKERMSAAELRSLEEMSLRRGFFNLNRSSKRESKTRLEISNPIPIKVASGSDLHLTDIDSDSNRGSV
ILDSGHLSTASSSDDLKGEEGSFRGSVLQRAAKFGSLAKQNSQMIVKRFSFSQRSRDESASETSTPSEHSAAPSPQVEVRTLEGQLVQHP
GPGIPRPGHRSRAPELVTKKFPVDLRLPPVVPLPPPTLRELELQRRPTGDFGFSLRRTTMLDRGPEGQACRRVVHFAEPGAGTKDLALGL
VPGDRLVEINGHNVESKSRDEIVEMIRQSGDSVRLKVQPIPELSELSRSWLRSGEGPRREPSDAKTEEQIAAEEAWNETEKVWLVHRDGF
SLASQLKSEELNLPEGKVRVKLDHDGAILDVDEDDVEKANAPSCDRLEDLASLVYLNESSVLHTLRQRYGASLLHTYAGPSLLVLGPRGA
PAVYSEKVMHMFKGCRREDMAPHIYAVAQTAYRAMLMSRQDQSIILLGSSGSGKTTSCQHLVQYLATIAGISGNKVFSVEKWQALYTLLE
AFGNSPTIINGNATRFSQILSLDFDQAGQVASASIQTMLLEKLRVARRPASEATFNVFYYLLACGDGTLRTELHLNHLAENNVFGIVPLA
KPEEKQKAAQQFSKLQAAMKVLGISPDEQKACWFILAAIYHLGAAGATKEAAEAGRKQFARHEWAQKAAYLLGCSLEELSSAIFKHQHKG
GTLQRSTSFRQGPEESGLGDGTGPKLSALECLEGMAAGLYSELFTLLVSLVNRALKSSQHSLCSMMIVDTPGFQNPEQGGSARGASFEEL
CHNYTQDRLQRLFHERTFVQELERYKEENIELAFDDLEPPTDDSVAAVDQASHQSLVRSLARTDEARGLLWLLEEEALVPGASEDTLLER
LFSYYGPQEGDKKGQSPLLHSSKPHHFLLGHSHGTNWVEYNVTGWLNYTKQNPATQNAPRLLQDSQKKIISNLFLGRAGSATVLSGSIAG
LEGGSQLALRRATSMRKTFTTGMAAVKKKSLCIQMKLQVDALIDTIKKSKLHFVHCFLPVAEGWAGEPRSASSRRVSSSSELDLPSGDHC
EAGLLQLDVPLLRTQLRGSRLLDAMRMYRQGYPDHMVFSEFRRRFDVLAPHLTKKHGRNYIVVDERRAVEELLECLDLEKSSCCMGLSRV
FFRAGTLARLEEQRDEQTSRNLTLFQAACRGYLARQHFKKRKIQDLAIRCVQKNIKKNKGVKDWPWWKLFTTVRPLIEVQLSEEQIRNKD
EEIQQLRSKLEKAEKERNELRLNSDRLESRISELTSELTDERNTGESASQLLDAETAERLRAEKEMKELQTQYDALKKQMEVMEMEVMEA
RLIRAAEINGEVDDDDAGGEWRLKYERAVREVDFTKKRLQQEFEDKLEVEQQNKRQLERRLGDLQADSEESQRALQQLKKKCQRLTAELQ
DTKLHLEGQQVRNHELEKKQRRFDSELSQAHEEAQREKLQREKLQREKDMLLAEAFSLKQQLEEKDMDIAGFTQKVVSLEAELQDISSQE
SKDEASLAKVKKQLRDLEAKVKDQEEELDEQAGTIQMLEQLKQMEVQLEEEYEDKQKVLREKRELEGKLATLSDQVNRRDFESEKRLRKD
LKRTKALLADAQLMLDHLKNSAPSKREIAQLKNQLEESEFTCAAAVKARKAMEVEIEDLHLQIDDIAKAKTALEEQLSRLQREKNEIQNR
LEEDQEDMNELMKKHKAAVAQASRDLAQINDLQAQLEEANKEKQELQEKLQALQSQVEFLEQSMVDKSLVSRQEAKIRELETRLEFERTQ
VKRLESLASRLKENMEKLTEERDQRIAAENREKEQNKRLQRQLRDTKEEMGELARKEAEASRKKHELEMDLESLEAANQSLQADLKLAFK
RIGDLQAAIEDEMESDENEDLINSEGDSDVDSELEDRVDGVKSWLSKNKGPSKAASDDGSLKSSSEKRHLQVNVTNPVQCSLHGKKCTVS

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Fusion Gene PPI Analysis for MYO18A-MYO1D


check button Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in

ChiPPI page.


check button Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160)
HgeneHgene's interactorsTgeneTgene's interactors


check button - Retained PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenStill interaction with


check button - Lost PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


check button - Retained PPIs, but lost function due to frame-shift fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


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Related Drugs for MYO18A-MYO1D


check button Drugs targeting genes involved in this fusion gene.
(DrugBank Version 5.1.8 2021-05-08)
PartnerGeneUniProtAccDrugBank IDDrug nameDrug activityDrug typeDrug status

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Related Diseases for MYO18A-MYO1D


check button Diseases associated with fusion partners.
(DisGeNet 4.0)
PartnerGeneDisease IDDisease name# pubmedsSource