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Center for Computational Systems Medicine
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Fusion Gene Summary

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Fusion Gene ORF analysis

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Fusion Genomic Features

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Fusion Protein Features

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Fusion Gene Sequence

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Fusion Gene PPI analysis

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Related Drugs

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Related Diseases

Fusion gene:MYO1D-PIGS (FusionGDB2 ID:56655)

Fusion Gene Summary for MYO1D-PIGS

check button Fusion gene summary
Fusion gene informationFusion gene name: MYO1D-PIGS
Fusion gene ID: 56655
HgeneTgene
Gene symbol

MYO1D

PIGS

Gene ID

4642

94005

Gene namemyosin IDphosphatidylinositol glycan anchor biosynthesis class S
SynonymsPPP1R108|myr4GPIBD18
Cytomap

17q11.2

17q11.2

Type of geneprotein-codingprotein-coding
Descriptionunconventional myosin-Idmyosin-I gammaprotein phosphatase 1, regulatory subunit 108GPI transamidase component PIG-SGPI transamidase subunitphosphatidylinositol glycan, class Sphosphatidylinositol-glycan biosynthesis class S protein
Modification date2020031320200313
UniProtAcc

O94832

.
Ensembl transtripts involved in fusion geneENST00000318217, ENST00000579584, 
ENST00000583621, ENST00000394649, 
ENST00000584232, 		ENST00000543734, 
ENST00000465444, ENST00000308360, 
ENST00000395346, 
Fusion gene scores* DoF score24 X 17 X 12=48964 X 4 X 3=48
# samples 284
** MAII scorelog2(28/4896*10)=-4.12810482574769
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0		log2(4/48*10)=-0.263034405833794
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0
Context

PubMed: MYO1D [Title/Abstract] AND PIGS [Title/Abstract] AND fusion [Title/Abstract]

Most frequent breakpointMYO1D(31203796)-PIGS(26897981), # samples:1
Anticipated loss of major functional domain due to fusion event.
* DoF score (Degree of Frequency) = # partners X # break points X # cancer types
** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)

check button Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez
PartnerGeneGO IDGO termPubMed ID
HgeneMYO1D

GO:0010923

negative regulation of phosphatase activity

19389623


check buttonFusion gene breakpoints across MYO1D (5'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check buttonFusion gene breakpoints across PIGS (3'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check button Fusion gene information from two resources (ChiTars 5.0 and ChimerDB 4.0)
* All genome coordinats were lifted-over on hg19.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
SourceDiseaseSampleHgeneHchrHbpHstrandTgeneTchrTbpTstrand
ChimerDB4COADTCGA-A6-5657-01AMYO1Dchr17

31203796

-PIGSchr17

26897981

-


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Fusion Gene ORF analysis for MYO1D-PIGS

check button Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
ORFHenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrand
5CDS-5UTRENST00000318217ENST00000543734MYO1Dchr17

31203796

-PIGSchr17

26897981

-
5CDS-5UTRENST00000579584ENST00000543734MYO1Dchr17

31203796

-PIGSchr17

26897981

-
5CDS-5UTRENST00000583621ENST00000543734MYO1Dchr17

31203796

-PIGSchr17

26897981

-
5CDS-intronENST00000318217ENST00000465444MYO1Dchr17

31203796

-PIGSchr17

26897981

-
5CDS-intronENST00000579584ENST00000465444MYO1Dchr17

31203796

-PIGSchr17

26897981

-
5CDS-intronENST00000583621ENST00000465444MYO1Dchr17

31203796

-PIGSchr17

26897981

-
In-frameENST00000318217ENST00000308360MYO1Dchr17

31203796

-PIGSchr17

26897981

-
In-frameENST00000318217ENST00000395346MYO1Dchr17

31203796

-PIGSchr17

26897981

-
In-frameENST00000579584ENST00000308360MYO1Dchr17

31203796

-PIGSchr17

26897981

-
In-frameENST00000579584ENST00000395346MYO1Dchr17

31203796

-PIGSchr17

26897981

-
In-frameENST00000583621ENST00000308360MYO1Dchr17

31203796

-PIGSchr17

26897981

-
In-frameENST00000583621ENST00000395346MYO1Dchr17

31203796

-PIGSchr17

26897981

-
intron-3CDSENST00000394649ENST00000308360MYO1Dchr17

31203796

-PIGSchr17

26897981

-
intron-3CDSENST00000394649ENST00000395346MYO1Dchr17

31203796

-PIGSchr17

26897981

-
intron-3CDSENST00000584232ENST00000308360MYO1Dchr17

31203796

-PIGSchr17

26897981

-
intron-3CDSENST00000584232ENST00000395346MYO1Dchr17

31203796

-PIGSchr17

26897981

-
intron-5UTRENST00000394649ENST00000543734MYO1Dchr17

31203796

-PIGSchr17

26897981

-
intron-5UTRENST00000584232ENST00000543734MYO1Dchr17

31203796

-PIGSchr17

26897981

-
intron-intronENST00000394649ENST00000465444MYO1Dchr17

31203796

-PIGSchr17

26897981

-
intron-intronENST00000584232ENST00000465444MYO1Dchr17

31203796

-PIGSchr17

26897981

-

check buttonORFfinder result based on the fusion transcript sequence of in-frame fusion genes.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandSeq length
(transcript)		BP loci
(transcript)		Predicted start
(transcript)		Predicted stop
(transcript)		Seq length
(amino acids)
ENST00000318217MYO1Dchr1731203796-ENST00000395346PIGSchr1726897981-27274004091893494
ENST00000318217MYO1Dchr1731203796-ENST00000308360PIGSchr1726897981-27274004091893494
ENST00000579584MYO1Dchr1731203796-ENST00000395346PIGSchr1726897981-26943673761860494
ENST00000579584MYO1Dchr1731203796-ENST00000308360PIGSchr1726897981-26943673761860494
ENST00000583621MYO1Dchr1731203796-ENST00000395346PIGSchr1726897981-27274004091893494
ENST00000583621MYO1Dchr1731203796-ENST00000308360PIGSchr1726897981-27274004091893494

check buttonDeepORF prediction of the coding potential based on the fusion transcript sequence of in-frame fusion genes. DeepORF is a coding potential classifier based on convolutional neural network by comparing the real Ribo-seq data. If the no-coding score < 0.5 and coding score > 0.5, then the in-frame fusion transcript is predicted as being likely translated.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandNo-coding scoreCoding score
ENST00000318217ENST00000395346MYO1Dchr1731203796-PIGSchr1726897981-0.0022805860.99771935
ENST00000318217ENST00000308360MYO1Dchr1731203796-PIGSchr1726897981-0.0022805860.99771935
ENST00000579584ENST00000395346MYO1Dchr1731203796-PIGSchr1726897981-0.0021579760.99784195
ENST00000579584ENST00000308360MYO1Dchr1731203796-PIGSchr1726897981-0.0021579760.99784195
ENST00000583621ENST00000395346MYO1Dchr1731203796-PIGSchr1726897981-0.0022805860.99771935
ENST00000583621ENST00000308360MYO1Dchr1731203796-PIGSchr1726897981-0.0022805860.99771935

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Fusion Genomic Features for MYO1D-PIGS


check buttonFusionAI prediction of the potential fusion gene breakpoint based on the pre-mature RNA sequence context (+/- 5kb of individual partner genes, total 20kb length sequence). FusionAI is a fusion gene breakpoint classifier based on convolutional neural network by comparing the fusion positive and negative sequence context of ~ 20K fusion gene data. From here, we can have the relative potentency of the 20K genomic sequence how individual sequnce will be likely used as the gene fusion breakpoints.
HgeneHchrHbpHstrandTgeneTchrTbpTstrand1-pp (fusion gene breakpoint)

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions. We integrated a total of 44 different types of human genomic feature loci information across five big categories including virus integration sites, repeats, structural variants, chromatin states, and gene expression regulation. More details are in help page.
genomic feature

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions that are ovelapped with the top 1% feature importance score regions. More details are in help page.

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Fusion Protein Features for MYO1D-PIGS


check button Four levels of functional features of fusion genes
Go to FGviewer search page for the most frequent breakpoint (https://ccsmweb.uth.edu/FGviewer/chr17:31203796/chr17:26897981)
- FGviewer provides the online visualization of the retention search of the protein functional features across DNA, RNA, protein, and pathological levels.
- How to search
1. Put your fusion gene symbol.
2. Press the tab key until there will be shown the breakpoint information filled.
4. Go down and press 'Search' tab twice.
4. Go down to have the hyperlink of the search result.
5. Click the hyperlink.
6. See the FGviewer result for your fusion gene.
FGviewer

check buttonMain function of each fusion partner protein. (from UniProt)
HgeneTgene
MYO1D

O94832

.
FUNCTION: Unconventional myosin that functions as actin-based motor protein with ATPase activity (By similarity). Plays a role in endosomal protein trafficking, and especially in the transfer of cargo proteins from early to recycling endosomes (By similarity). Required for normal planar cell polarity in ciliated tracheal cells, for normal rotational polarity of cilia, and for coordinated, unidirectional ciliary movement in the trachea. Required for normal, polarized cilia organization in brain ependymal epithelial cells (By similarity). {ECO:0000250|UniProtKB:F1PRN2, ECO:0000250|UniProtKB:Q63357}.FUNCTION: Transcriptional activator which is required for calcium-dependent dendritic growth and branching in cortical neurons. Recruits CREB-binding protein (CREBBP) to nuclear bodies. Component of the CREST-BRG1 complex, a multiprotein complex that regulates promoter activation by orchestrating a calcium-dependent release of a repressor complex and a recruitment of an activator complex. In resting neurons, transcription of the c-FOS promoter is inhibited by BRG1-dependent recruitment of a phospho-RB1-HDAC1 repressor complex. Upon calcium influx, RB1 is dephosphorylated by calcineurin, which leads to release of the repressor complex. At the same time, there is increased recruitment of CREBBP to the promoter by a CREST-dependent mechanism, which leads to transcriptional activation. The CREST-BRG1 complex also binds to the NR2B promoter, and activity-dependent induction of NR2B expression involves a release of HDAC1 and recruitment of CREBBP (By similarity). {ECO:0000250}.

check buttonRetention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at

download page


* Minus value of BPloci means that the break pointn is located before the CDS.
- In-frame and retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
TgenePIGSchr17:31203796chr17:26897981ENST00000308360112542_55558556.0Topological domainCytoplasmic
TgenePIGSchr17:31203796chr17:26897981ENST00000395346011542_55550548.0Topological domainCytoplasmic
TgenePIGSchr17:31203796chr17:26897981ENST00000308360112521_54158556.0TransmembraneHelical
TgenePIGSchr17:31203796chr17:26897981ENST00000395346011521_54150548.0TransmembraneHelical

- In-frame and not-retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneMYO1Dchr17:31203796chr17:26897981ENST00000318217-122699_719311007.0DomainIQ 1
HgeneMYO1Dchr17:31203796chr17:26897981ENST00000318217-122721_741311007.0DomainIQ 2
HgeneMYO1Dchr17:31203796chr17:26897981ENST00000318217-122812_1005311007.0DomainTH1
HgeneMYO1Dchr17:31203796chr17:26897981ENST00000318217-1229_695311007.0DomainMyosin motor
HgeneMYO1Dchr17:31203796chr17:26897981ENST00000318217-122102_109311007.0Nucleotide bindingATP
HgeneMYO1Dchr17:31203796chr17:26897981ENST00000318217-122572_594311007.0RegionActin-binding
TgenePIGSchr17:31203796chr17:26897981ENST000003083601122_1858556.0Topological domainCytoplasmic
TgenePIGSchr17:31203796chr17:26897981ENST0000030836011240_52058556.0Topological domainLumenal
TgenePIGSchr17:31203796chr17:26897981ENST000003953460112_1850548.0Topological domainCytoplasmic
TgenePIGSchr17:31203796chr17:26897981ENST0000039534601140_52050548.0Topological domainLumenal
TgenePIGSchr17:31203796chr17:26897981ENST0000030836011219_3958556.0TransmembraneHelical
TgenePIGSchr17:31203796chr17:26897981ENST0000039534601119_3950548.0TransmembraneHelical


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Fusion Gene Sequence for MYO1D-PIGS


check button For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. To have fusion amino acid sequence, we ran ORFfinder and chose the longest ORF among the all predicted ones.
>56655_56655_1_MYO1D-PIGS_MYO1D_chr17_31203796_ENST00000318217_PIGS_chr17_26897981_ENST00000308360_length(transcript)=2727nt_BP=400nt
AGGCTGGAGGCGGGACCAGCCGCTGCCGTCTCCGTCTCGGTGTCCCGGCCCCTACAGCGCCCGGCAGCCGCGGCGGGAGGAGCGGAAACT
GTCGGGTGCGTCCCGTTCGGAGCCGCGCCGGCCGAGAAGGCGCCGAGGAGCAGCGAGGCGGCCTCTGTCCGGCCCGGACCCGCCGAGCGG
CGTGCGCGCCCCCTCCCCGTAGCCTCGCGGCGCGGCCTCGCCCCGGCCCCTCCCGAGCTCATCGCGGGCCCACGGAGCGGCCCCGGAGGC
CCGAGCGCGCCCACCTGAGCCCCCGCGCTGGCGCCATGGCGGAGCAGGAGAGCCTGGAATTCGGCAAGGCAGACTTCGTGCTGATGGACA
CCGTCTCCATGCCCGAGTTCATGGCCAACCTCAGGCTCAGCTCCGCCTCATGGTGCCTGTCACTGTCGTGTTTACGCGGGAGTCAGTGCC
CCTGGACGACCAGGAGAAGCTGCCCTTCACCGTTGTGCATGAAAGAGAGATTCCTCTGAAATACAAAATGAAAATCAAATGCCGTTTCCA
GAAGGCCTATCGGAGGGCTTTGGACCATGAGGAGGAGGCCCTGTCATCGGGCAGTGTGCAAGAGGCAGAAGCCATGTTAGATGAGCCTCA
GGAACAAGCGGAGGGCTCCCTGACTGTGTACGTGATATCTGAACACTCCTCACTTCTTCCCCAGGACATGATGAGCTACATTGGGCCCAA
GAGGACAGCAGTGGTGCGGGGGATAATGCACCGGGAGGCCTTTAACATCATTGGCCGCCGCATAGTCCAGGTGGCCCAGGCCATGTCTTT
GACTGAGGATGTGCTTGCTGCTGCTCTGGCTGACCACCTTCCAGAGGACAAGTGGAGCGCTGAGAAGAGGCGGCCTCTCAAGTCCAGCTT
GGGCTATGAGATCACCTTCAGTTTACTCAACCCAGACCCCAAGTCCCATGATGTCTACTGGGACATTGAGGGGGCTGTCCGGCGCTATGT
GCAACCTTTCCTGAATGCCCTCGGTGCCGCTGGCAACTTCTCTGTGGACTCTCAGATTCTTTACTATGCAATGTTGGGGGTGAATCCCCG
CTTTGACTCAGCTTCCTCCAGCTACTATTTGGACATGCACAGCCTCCCCCATGTCATCAACCCAGTGGAGTCCCGGCTGGGATCCAGTGC
TGCCTCCTTGTACCCTGTGCTCAACTTTCTACTCTACGTGCCTGAGCTTGCACACTCACCGCTGTACATTCAGGACAAGGATGGCGCTCC
AGTGGCCACCAATGCCTTCCATAGTCCCCGCTGGGGTGGCATTATGGTATATAATGTTGACTCCAAAACCTATAATGCCTCAGTGCTGCC
AGTGAGAGTCGAGGTGGACATGGTGCGAGTGATGGAGGTGTTCCTGGCACAGTTGCGGTTGCTCTTTGGGATTGCTCAGCCCCAGCTGCC
TCCAAAATGCCTGCTTTCAGGGCCTACGAGTGAAGGGCTAATGACCTGGGAGCTAGACCGGCTGCTCTGGGCTCGGTCAGTGGAGAACCT
GGCCACAGCCACCACCACCCTTACCTCCCTGGCGCAGCTTCTGGGCAAGATCAGCAACATTGTCATTAAGGACGACGTGGCATCTGAGGT
GTACAAGGCTGTAGCTGCCGTCCAGAAGTCGGCAGAAGAGTTGGCGTCTGGGCACCTGGCATCTGCCTTTGTCGCCAGCCAGGAAGCTGT
GACATCCTCTGAGCTTGCCTTCTTTGACCCGTCACTCCTCCACCTCCTTTATTTCCCTGATGACCAGAAGTTTGCCATCTACATCCCACT
CTTCCTGCCTATGGCTGTGCCCATCCTCCTGTCCCTGGTCAAGATCTTCCTGGAGACCCGCAAGTCCTGGAGAAAGCCTGAGAAGACAGA
CTGAGCAGGGCAGCACCTCCATAGGAAGCCTTCCTTTCTGGCCAAGGTGGGCGGTGTTAGATTGTGAGGCACGTACATGGGGCCTGCCGG
AATGACTTAAATATTTGTCTCCAGTCTCCACTGTTGGCTCTCCAGCAACCAAAGTACAACACTCCAAGATGGGTTCATCTTTTCTTCCTT
TCCCATTCACCTGGCTCAATCCTCCTCCACCACCAGGGGCCTCAAAAGGCACATCATCCGGGTCTCCTTATCTTGTTTGATAAGGCTGCT
GCCTGTCTCCCTCTGTGGCAAGGACTGTTTGTTCTTTTGCCCCATTTCTCAACATAGCACACTTGTGCACTGAGAGGAGGGAGCATTATG
GGAAAGTCCCTGCCTTCCACACCTCTCTCTAGTCCCTGTGGGACAGCCCTAGCCCCTGCTGTCATGAAGGGGCCAGGCATTGGTCACCTG
TGGGACCTTCTCCCTCACTCCCCTCCCTCCTAGTTGGCTTTGTCTGTCAGGTGCAGTCTGGCGGGAGTCCAGGAGGCAGCAGCTCAGGAC
ATGGTGCTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTCAGAGGTTCCAGAAAGTTCCAGATTTGGAATCAAACAGTCCTGAAT
TCAAATCCTTGTTTTTGCACTTATTGTCTGGAGAGCTTTGGATAAGGTATTGAATCTCTCTGAGCCTCAGTTTTTCATTTGTTCAAATGG
CACTGATGATGTCTCCCTTACAAGATGGTTGTGAGGAGTAAATGTGATCAGCATGTAAAGTGTCTGGCGTGTAGTAGGCTCTTAATAAAC

>56655_56655_1_MYO1D-PIGS_MYO1D_chr17_31203796_ENST00000318217_PIGS_chr17_26897981_ENST00000308360_length(amino acids)=494AA_BP=
MVPVTVVFTRESVPLDDQEKLPFTVVHEREIPLKYKMKIKCRFQKAYRRALDHEEEALSSGSVQEAEAMLDEPQEQAEGSLTVYVISEHS
SLLPQDMMSYIGPKRTAVVRGIMHREAFNIIGRRIVQVAQAMSLTEDVLAAALADHLPEDKWSAEKRRPLKSSLGYEITFSLLNPDPKSH
DVYWDIEGAVRRYVQPFLNALGAAGNFSVDSQILYYAMLGVNPRFDSASSSYYLDMHSLPHVINPVESRLGSSAASLYPVLNFLLYVPEL
AHSPLYIQDKDGAPVATNAFHSPRWGGIMVYNVDSKTYNASVLPVRVEVDMVRVMEVFLAQLRLLFGIAQPQLPPKCLLSGPTSEGLMTW
ELDRLLWARSVENLATATTTLTSLAQLLGKISNIVIKDDVASEVYKAVAAVQKSAEELASGHLASAFVASQEAVTSSELAFFDPSLLHLL

--------------------------------------------------------------
>56655_56655_2_MYO1D-PIGS_MYO1D_chr17_31203796_ENST00000318217_PIGS_chr17_26897981_ENST00000395346_length(transcript)=2727nt_BP=400nt
AGGCTGGAGGCGGGACCAGCCGCTGCCGTCTCCGTCTCGGTGTCCCGGCCCCTACAGCGCCCGGCAGCCGCGGCGGGAGGAGCGGAAACT
GTCGGGTGCGTCCCGTTCGGAGCCGCGCCGGCCGAGAAGGCGCCGAGGAGCAGCGAGGCGGCCTCTGTCCGGCCCGGACCCGCCGAGCGG
CGTGCGCGCCCCCTCCCCGTAGCCTCGCGGCGCGGCCTCGCCCCGGCCCCTCCCGAGCTCATCGCGGGCCCACGGAGCGGCCCCGGAGGC
CCGAGCGCGCCCACCTGAGCCCCCGCGCTGGCGCCATGGCGGAGCAGGAGAGCCTGGAATTCGGCAAGGCAGACTTCGTGCTGATGGACA
CCGTCTCCATGCCCGAGTTCATGGCCAACCTCAGGCTCAGCTCCGCCTCATGGTGCCTGTCACTGTCGTGTTTACGCGGGAGTCAGTGCC
CCTGGACGACCAGGAGAAGCTGCCCTTCACCGTTGTGCATGAAAGAGAGATTCCTCTGAAATACAAAATGAAAATCAAATGCCGTTTCCA
GAAGGCCTATCGGAGGGCTTTGGACCATGAGGAGGAGGCCCTGTCATCGGGCAGTGTGCAAGAGGCAGAAGCCATGTTAGATGAGCCTCA
GGAACAAGCGGAGGGCTCCCTGACTGTGTACGTGATATCTGAACACTCCTCACTTCTTCCCCAGGACATGATGAGCTACATTGGGCCCAA
GAGGACAGCAGTGGTGCGGGGGATAATGCACCGGGAGGCCTTTAACATCATTGGCCGCCGCATAGTCCAGGTGGCCCAGGCCATGTCTTT
GACTGAGGATGTGCTTGCTGCTGCTCTGGCTGACCACCTTCCAGAGGACAAGTGGAGCGCTGAGAAGAGGCGGCCTCTCAAGTCCAGCTT
GGGCTATGAGATCACCTTCAGTTTACTCAACCCAGACCCCAAGTCCCATGATGTCTACTGGGACATTGAGGGGGCTGTCCGGCGCTATGT
GCAACCTTTCCTGAATGCCCTCGGTGCCGCTGGCAACTTCTCTGTGGACTCTCAGATTCTTTACTATGCAATGTTGGGGGTGAATCCCCG
CTTTGACTCAGCTTCCTCCAGCTACTATTTGGACATGCACAGCCTCCCCCATGTCATCAACCCAGTGGAGTCCCGGCTGGGATCCAGTGC
TGCCTCCTTGTACCCTGTGCTCAACTTTCTACTCTACGTGCCTGAGCTTGCACACTCACCGCTGTACATTCAGGACAAGGATGGCGCTCC
AGTGGCCACCAATGCCTTCCATAGTCCCCGCTGGGGTGGCATTATGGTATATAATGTTGACTCCAAAACCTATAATGCCTCAGTGCTGCC
AGTGAGAGTCGAGGTGGACATGGTGCGAGTGATGGAGGTGTTCCTGGCACAGTTGCGGTTGCTCTTTGGGATTGCTCAGCCCCAGCTGCC
TCCAAAATGCCTGCTTTCAGGGCCTACGAGTGAAGGGCTAATGACCTGGGAGCTAGACCGGCTGCTCTGGGCTCGGTCAGTGGAGAACCT
GGCCACAGCCACCACCACCCTTACCTCCCTGGCGCAGCTTCTGGGCAAGATCAGCAACATTGTCATTAAGGACGACGTGGCATCTGAGGT
GTACAAGGCTGTAGCTGCCGTCCAGAAGTCGGCAGAAGAGTTGGCGTCTGGGCACCTGGCATCTGCCTTTGTCGCCAGCCAGGAAGCTGT
GACATCCTCTGAGCTTGCCTTCTTTGACCCGTCACTCCTCCACCTCCTTTATTTCCCTGATGACCAGAAGTTTGCCATCTACATCCCACT
CTTCCTGCCTATGGCTGTGCCCATCCTCCTGTCCCTGGTCAAGATCTTCCTGGAGACCCGCAAGTCCTGGAGAAAGCCTGAGAAGACAGA
CTGAGCAGGGCAGCACCTCCATAGGAAGCCTTCCTTTCTGGCCAAGGTGGGCGGTGTTAGATTGTGAGGCACGTACATGGGGCCTGCCGG
AATGACTTAAATATTTGTCTCCAGTCTCCACTGTTGGCTCTCCAGCAACCAAAGTACAACACTCCAAGATGGGTTCATCTTTTCTTCCTT
TCCCATTCACCTGGCTCAATCCTCCTCCACCACCAGGGGCCTCAAAAGGCACATCATCCGGGTCTCCTTATCTTGTTTGATAAGGCTGCT
GCCTGTCTCCCTCTGTGGCAAGGACTGTTTGTTCTTTTGCCCCATTTCTCAACATAGCACACTTGTGCACTGAGAGGAGGGAGCATTATG
GGAAAGTCCCTGCCTTCCACACCTCTCTCTAGTCCCTGTGGGACAGCCCTAGCCCCTGCTGTCATGAAGGGGCCAGGCATTGGTCACCTG
TGGGACCTTCTCCCTCACTCCCCTCCCTCCTAGTTGGCTTTGTCTGTCAGGTGCAGTCTGGCGGGAGTCCAGGAGGCAGCAGCTCAGGAC
ATGGTGCTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTCAGAGGTTCCAGAAAGTTCCAGATTTGGAATCAAACAGTCCTGAAT
TCAAATCCTTGTTTTTGCACTTATTGTCTGGAGAGCTTTGGATAAGGTATTGAATCTCTCTGAGCCTCAGTTTTTCATTTGTTCAAATGG
CACTGATGATGTCTCCCTTACAAGATGGTTGTGAGGAGTAAATGTGATCAGCATGTAAAGTGTCTGGCGTGTAGTAGGCTCTTAATAAAC

>56655_56655_2_MYO1D-PIGS_MYO1D_chr17_31203796_ENST00000318217_PIGS_chr17_26897981_ENST00000395346_length(amino acids)=494AA_BP=
MVPVTVVFTRESVPLDDQEKLPFTVVHEREIPLKYKMKIKCRFQKAYRRALDHEEEALSSGSVQEAEAMLDEPQEQAEGSLTVYVISEHS
SLLPQDMMSYIGPKRTAVVRGIMHREAFNIIGRRIVQVAQAMSLTEDVLAAALADHLPEDKWSAEKRRPLKSSLGYEITFSLLNPDPKSH
DVYWDIEGAVRRYVQPFLNALGAAGNFSVDSQILYYAMLGVNPRFDSASSSYYLDMHSLPHVINPVESRLGSSAASLYPVLNFLLYVPEL
AHSPLYIQDKDGAPVATNAFHSPRWGGIMVYNVDSKTYNASVLPVRVEVDMVRVMEVFLAQLRLLFGIAQPQLPPKCLLSGPTSEGLMTW
ELDRLLWARSVENLATATTTLTSLAQLLGKISNIVIKDDVASEVYKAVAAVQKSAEELASGHLASAFVASQEAVTSSELAFFDPSLLHLL

--------------------------------------------------------------
>56655_56655_3_MYO1D-PIGS_MYO1D_chr17_31203796_ENST00000579584_PIGS_chr17_26897981_ENST00000308360_length(transcript)=2694nt_BP=367nt
GTCTCGGTGTCCCGGCCCCTACAGCGCCCGGCAGCCGCGGCGGGAGGAGCGGAAACTGTCGGGTGCGTCCCGTTCGGAGCCGCGCCGGCC
GAGAAGGCGCCGAGGAGCAGCGAGGCGGCCTCTGTCCGGCCCGGACCCGCCGAGCGGCGTGCGCGCCCCCTCCCCGTAGCCTCGCGGCGC
GGCCTCGCCCCGGCCCCTCCCGAGCTCATCGCGGGCCCACGGAGCGGCCCCGGAGGCCCGAGCGCGCCCACCTGAGCCCCCGCGCTGGCG
CCATGGCGGAGCAGGAGAGCCTGGAATTCGGCAAGGCAGACTTCGTGCTGATGGACACCGTCTCCATGCCCGAGTTCATGGCCAACCTCA
GGCTCAGCTCCGCCTCATGGTGCCTGTCACTGTCGTGTTTACGCGGGAGTCAGTGCCCCTGGACGACCAGGAGAAGCTGCCCTTCACCGT
TGTGCATGAAAGAGAGATTCCTCTGAAATACAAAATGAAAATCAAATGCCGTTTCCAGAAGGCCTATCGGAGGGCTTTGGACCATGAGGA
GGAGGCCCTGTCATCGGGCAGTGTGCAAGAGGCAGAAGCCATGTTAGATGAGCCTCAGGAACAAGCGGAGGGCTCCCTGACTGTGTACGT
GATATCTGAACACTCCTCACTTCTTCCCCAGGACATGATGAGCTACATTGGGCCCAAGAGGACAGCAGTGGTGCGGGGGATAATGCACCG
GGAGGCCTTTAACATCATTGGCCGCCGCATAGTCCAGGTGGCCCAGGCCATGTCTTTGACTGAGGATGTGCTTGCTGCTGCTCTGGCTGA
CCACCTTCCAGAGGACAAGTGGAGCGCTGAGAAGAGGCGGCCTCTCAAGTCCAGCTTGGGCTATGAGATCACCTTCAGTTTACTCAACCC
AGACCCCAAGTCCCATGATGTCTACTGGGACATTGAGGGGGCTGTCCGGCGCTATGTGCAACCTTTCCTGAATGCCCTCGGTGCCGCTGG
CAACTTCTCTGTGGACTCTCAGATTCTTTACTATGCAATGTTGGGGGTGAATCCCCGCTTTGACTCAGCTTCCTCCAGCTACTATTTGGA
CATGCACAGCCTCCCCCATGTCATCAACCCAGTGGAGTCCCGGCTGGGATCCAGTGCTGCCTCCTTGTACCCTGTGCTCAACTTTCTACT
CTACGTGCCTGAGCTTGCACACTCACCGCTGTACATTCAGGACAAGGATGGCGCTCCAGTGGCCACCAATGCCTTCCATAGTCCCCGCTG
GGGTGGCATTATGGTATATAATGTTGACTCCAAAACCTATAATGCCTCAGTGCTGCCAGTGAGAGTCGAGGTGGACATGGTGCGAGTGAT
GGAGGTGTTCCTGGCACAGTTGCGGTTGCTCTTTGGGATTGCTCAGCCCCAGCTGCCTCCAAAATGCCTGCTTTCAGGGCCTACGAGTGA
AGGGCTAATGACCTGGGAGCTAGACCGGCTGCTCTGGGCTCGGTCAGTGGAGAACCTGGCCACAGCCACCACCACCCTTACCTCCCTGGC
GCAGCTTCTGGGCAAGATCAGCAACATTGTCATTAAGGACGACGTGGCATCTGAGGTGTACAAGGCTGTAGCTGCCGTCCAGAAGTCGGC
AGAAGAGTTGGCGTCTGGGCACCTGGCATCTGCCTTTGTCGCCAGCCAGGAAGCTGTGACATCCTCTGAGCTTGCCTTCTTTGACCCGTC
ACTCCTCCACCTCCTTTATTTCCCTGATGACCAGAAGTTTGCCATCTACATCCCACTCTTCCTGCCTATGGCTGTGCCCATCCTCCTGTC
CCTGGTCAAGATCTTCCTGGAGACCCGCAAGTCCTGGAGAAAGCCTGAGAAGACAGACTGAGCAGGGCAGCACCTCCATAGGAAGCCTTC
CTTTCTGGCCAAGGTGGGCGGTGTTAGATTGTGAGGCACGTACATGGGGCCTGCCGGAATGACTTAAATATTTGTCTCCAGTCTCCACTG
TTGGCTCTCCAGCAACCAAAGTACAACACTCCAAGATGGGTTCATCTTTTCTTCCTTTCCCATTCACCTGGCTCAATCCTCCTCCACCAC
CAGGGGCCTCAAAAGGCACATCATCCGGGTCTCCTTATCTTGTTTGATAAGGCTGCTGCCTGTCTCCCTCTGTGGCAAGGACTGTTTGTT
CTTTTGCCCCATTTCTCAACATAGCACACTTGTGCACTGAGAGGAGGGAGCATTATGGGAAAGTCCCTGCCTTCCACACCTCTCTCTAGT
CCCTGTGGGACAGCCCTAGCCCCTGCTGTCATGAAGGGGCCAGGCATTGGTCACCTGTGGGACCTTCTCCCTCACTCCCCTCCCTCCTAG
TTGGCTTTGTCTGTCAGGTGCAGTCTGGCGGGAGTCCAGGAGGCAGCAGCTCAGGACATGGTGCTGTGTGTGTGTGTGTGTGTGTGTGTG
TGTGTGTGTGTCAGAGGTTCCAGAAAGTTCCAGATTTGGAATCAAACAGTCCTGAATTCAAATCCTTGTTTTTGCACTTATTGTCTGGAG
AGCTTTGGATAAGGTATTGAATCTCTCTGAGCCTCAGTTTTTCATTTGTTCAAATGGCACTGATGATGTCTCCCTTACAAGATGGTTGTG

>56655_56655_3_MYO1D-PIGS_MYO1D_chr17_31203796_ENST00000579584_PIGS_chr17_26897981_ENST00000308360_length(amino acids)=494AA_BP=
MVPVTVVFTRESVPLDDQEKLPFTVVHEREIPLKYKMKIKCRFQKAYRRALDHEEEALSSGSVQEAEAMLDEPQEQAEGSLTVYVISEHS
SLLPQDMMSYIGPKRTAVVRGIMHREAFNIIGRRIVQVAQAMSLTEDVLAAALADHLPEDKWSAEKRRPLKSSLGYEITFSLLNPDPKSH
DVYWDIEGAVRRYVQPFLNALGAAGNFSVDSQILYYAMLGVNPRFDSASSSYYLDMHSLPHVINPVESRLGSSAASLYPVLNFLLYVPEL
AHSPLYIQDKDGAPVATNAFHSPRWGGIMVYNVDSKTYNASVLPVRVEVDMVRVMEVFLAQLRLLFGIAQPQLPPKCLLSGPTSEGLMTW
ELDRLLWARSVENLATATTTLTSLAQLLGKISNIVIKDDVASEVYKAVAAVQKSAEELASGHLASAFVASQEAVTSSELAFFDPSLLHLL

--------------------------------------------------------------
>56655_56655_4_MYO1D-PIGS_MYO1D_chr17_31203796_ENST00000579584_PIGS_chr17_26897981_ENST00000395346_length(transcript)=2694nt_BP=367nt
GTCTCGGTGTCCCGGCCCCTACAGCGCCCGGCAGCCGCGGCGGGAGGAGCGGAAACTGTCGGGTGCGTCCCGTTCGGAGCCGCGCCGGCC
GAGAAGGCGCCGAGGAGCAGCGAGGCGGCCTCTGTCCGGCCCGGACCCGCCGAGCGGCGTGCGCGCCCCCTCCCCGTAGCCTCGCGGCGC
GGCCTCGCCCCGGCCCCTCCCGAGCTCATCGCGGGCCCACGGAGCGGCCCCGGAGGCCCGAGCGCGCCCACCTGAGCCCCCGCGCTGGCG
CCATGGCGGAGCAGGAGAGCCTGGAATTCGGCAAGGCAGACTTCGTGCTGATGGACACCGTCTCCATGCCCGAGTTCATGGCCAACCTCA
GGCTCAGCTCCGCCTCATGGTGCCTGTCACTGTCGTGTTTACGCGGGAGTCAGTGCCCCTGGACGACCAGGAGAAGCTGCCCTTCACCGT
TGTGCATGAAAGAGAGATTCCTCTGAAATACAAAATGAAAATCAAATGCCGTTTCCAGAAGGCCTATCGGAGGGCTTTGGACCATGAGGA
GGAGGCCCTGTCATCGGGCAGTGTGCAAGAGGCAGAAGCCATGTTAGATGAGCCTCAGGAACAAGCGGAGGGCTCCCTGACTGTGTACGT
GATATCTGAACACTCCTCACTTCTTCCCCAGGACATGATGAGCTACATTGGGCCCAAGAGGACAGCAGTGGTGCGGGGGATAATGCACCG
GGAGGCCTTTAACATCATTGGCCGCCGCATAGTCCAGGTGGCCCAGGCCATGTCTTTGACTGAGGATGTGCTTGCTGCTGCTCTGGCTGA
CCACCTTCCAGAGGACAAGTGGAGCGCTGAGAAGAGGCGGCCTCTCAAGTCCAGCTTGGGCTATGAGATCACCTTCAGTTTACTCAACCC
AGACCCCAAGTCCCATGATGTCTACTGGGACATTGAGGGGGCTGTCCGGCGCTATGTGCAACCTTTCCTGAATGCCCTCGGTGCCGCTGG
CAACTTCTCTGTGGACTCTCAGATTCTTTACTATGCAATGTTGGGGGTGAATCCCCGCTTTGACTCAGCTTCCTCCAGCTACTATTTGGA
CATGCACAGCCTCCCCCATGTCATCAACCCAGTGGAGTCCCGGCTGGGATCCAGTGCTGCCTCCTTGTACCCTGTGCTCAACTTTCTACT
CTACGTGCCTGAGCTTGCACACTCACCGCTGTACATTCAGGACAAGGATGGCGCTCCAGTGGCCACCAATGCCTTCCATAGTCCCCGCTG
GGGTGGCATTATGGTATATAATGTTGACTCCAAAACCTATAATGCCTCAGTGCTGCCAGTGAGAGTCGAGGTGGACATGGTGCGAGTGAT
GGAGGTGTTCCTGGCACAGTTGCGGTTGCTCTTTGGGATTGCTCAGCCCCAGCTGCCTCCAAAATGCCTGCTTTCAGGGCCTACGAGTGA
AGGGCTAATGACCTGGGAGCTAGACCGGCTGCTCTGGGCTCGGTCAGTGGAGAACCTGGCCACAGCCACCACCACCCTTACCTCCCTGGC
GCAGCTTCTGGGCAAGATCAGCAACATTGTCATTAAGGACGACGTGGCATCTGAGGTGTACAAGGCTGTAGCTGCCGTCCAGAAGTCGGC
AGAAGAGTTGGCGTCTGGGCACCTGGCATCTGCCTTTGTCGCCAGCCAGGAAGCTGTGACATCCTCTGAGCTTGCCTTCTTTGACCCGTC
ACTCCTCCACCTCCTTTATTTCCCTGATGACCAGAAGTTTGCCATCTACATCCCACTCTTCCTGCCTATGGCTGTGCCCATCCTCCTGTC
CCTGGTCAAGATCTTCCTGGAGACCCGCAAGTCCTGGAGAAAGCCTGAGAAGACAGACTGAGCAGGGCAGCACCTCCATAGGAAGCCTTC
CTTTCTGGCCAAGGTGGGCGGTGTTAGATTGTGAGGCACGTACATGGGGCCTGCCGGAATGACTTAAATATTTGTCTCCAGTCTCCACTG
TTGGCTCTCCAGCAACCAAAGTACAACACTCCAAGATGGGTTCATCTTTTCTTCCTTTCCCATTCACCTGGCTCAATCCTCCTCCACCAC
CAGGGGCCTCAAAAGGCACATCATCCGGGTCTCCTTATCTTGTTTGATAAGGCTGCTGCCTGTCTCCCTCTGTGGCAAGGACTGTTTGTT
CTTTTGCCCCATTTCTCAACATAGCACACTTGTGCACTGAGAGGAGGGAGCATTATGGGAAAGTCCCTGCCTTCCACACCTCTCTCTAGT
CCCTGTGGGACAGCCCTAGCCCCTGCTGTCATGAAGGGGCCAGGCATTGGTCACCTGTGGGACCTTCTCCCTCACTCCCCTCCCTCCTAG
TTGGCTTTGTCTGTCAGGTGCAGTCTGGCGGGAGTCCAGGAGGCAGCAGCTCAGGACATGGTGCTGTGTGTGTGTGTGTGTGTGTGTGTG
TGTGTGTGTGTCAGAGGTTCCAGAAAGTTCCAGATTTGGAATCAAACAGTCCTGAATTCAAATCCTTGTTTTTGCACTTATTGTCTGGAG
AGCTTTGGATAAGGTATTGAATCTCTCTGAGCCTCAGTTTTTCATTTGTTCAAATGGCACTGATGATGTCTCCCTTACAAGATGGTTGTG

>56655_56655_4_MYO1D-PIGS_MYO1D_chr17_31203796_ENST00000579584_PIGS_chr17_26897981_ENST00000395346_length(amino acids)=494AA_BP=
MVPVTVVFTRESVPLDDQEKLPFTVVHEREIPLKYKMKIKCRFQKAYRRALDHEEEALSSGSVQEAEAMLDEPQEQAEGSLTVYVISEHS
SLLPQDMMSYIGPKRTAVVRGIMHREAFNIIGRRIVQVAQAMSLTEDVLAAALADHLPEDKWSAEKRRPLKSSLGYEITFSLLNPDPKSH
DVYWDIEGAVRRYVQPFLNALGAAGNFSVDSQILYYAMLGVNPRFDSASSSYYLDMHSLPHVINPVESRLGSSAASLYPVLNFLLYVPEL
AHSPLYIQDKDGAPVATNAFHSPRWGGIMVYNVDSKTYNASVLPVRVEVDMVRVMEVFLAQLRLLFGIAQPQLPPKCLLSGPTSEGLMTW
ELDRLLWARSVENLATATTTLTSLAQLLGKISNIVIKDDVASEVYKAVAAVQKSAEELASGHLASAFVASQEAVTSSELAFFDPSLLHLL

--------------------------------------------------------------
>56655_56655_5_MYO1D-PIGS_MYO1D_chr17_31203796_ENST00000583621_PIGS_chr17_26897981_ENST00000308360_length(transcript)=2727nt_BP=400nt
AGGCTGGAGGCGGGACCAGCCGCTGCCGTCTCCGTCTCGGTGTCCCGGCCCCTACAGCGCCCGGCAGCCGCGGCGGGAGGAGCGGAAACT
GTCGGGTGCGTCCCGTTCGGAGCCGCGCCGGCCGAGAAGGCGCCGAGGAGCAGCGAGGCGGCCTCTGTCCGGCCCGGACCCGCCGAGCGG
CGTGCGCGCCCCCTCCCCGTAGCCTCGCGGCGCGGCCTCGCCCCGGCCCCTCCCGAGCTCATCGCGGGCCCACGGAGCGGCCCCGGAGGC
CCGAGCGCGCCCACCTGAGCCCCCGCGCTGGCGCCATGGCGGAGCAGGAGAGCCTGGAATTCGGCAAGGCAGACTTCGTGCTGATGGACA
CCGTCTCCATGCCCGAGTTCATGGCCAACCTCAGGCTCAGCTCCGCCTCATGGTGCCTGTCACTGTCGTGTTTACGCGGGAGTCAGTGCC
CCTGGACGACCAGGAGAAGCTGCCCTTCACCGTTGTGCATGAAAGAGAGATTCCTCTGAAATACAAAATGAAAATCAAATGCCGTTTCCA
GAAGGCCTATCGGAGGGCTTTGGACCATGAGGAGGAGGCCCTGTCATCGGGCAGTGTGCAAGAGGCAGAAGCCATGTTAGATGAGCCTCA
GGAACAAGCGGAGGGCTCCCTGACTGTGTACGTGATATCTGAACACTCCTCACTTCTTCCCCAGGACATGATGAGCTACATTGGGCCCAA
GAGGACAGCAGTGGTGCGGGGGATAATGCACCGGGAGGCCTTTAACATCATTGGCCGCCGCATAGTCCAGGTGGCCCAGGCCATGTCTTT
GACTGAGGATGTGCTTGCTGCTGCTCTGGCTGACCACCTTCCAGAGGACAAGTGGAGCGCTGAGAAGAGGCGGCCTCTCAAGTCCAGCTT
GGGCTATGAGATCACCTTCAGTTTACTCAACCCAGACCCCAAGTCCCATGATGTCTACTGGGACATTGAGGGGGCTGTCCGGCGCTATGT
GCAACCTTTCCTGAATGCCCTCGGTGCCGCTGGCAACTTCTCTGTGGACTCTCAGATTCTTTACTATGCAATGTTGGGGGTGAATCCCCG
CTTTGACTCAGCTTCCTCCAGCTACTATTTGGACATGCACAGCCTCCCCCATGTCATCAACCCAGTGGAGTCCCGGCTGGGATCCAGTGC
TGCCTCCTTGTACCCTGTGCTCAACTTTCTACTCTACGTGCCTGAGCTTGCACACTCACCGCTGTACATTCAGGACAAGGATGGCGCTCC
AGTGGCCACCAATGCCTTCCATAGTCCCCGCTGGGGTGGCATTATGGTATATAATGTTGACTCCAAAACCTATAATGCCTCAGTGCTGCC
AGTGAGAGTCGAGGTGGACATGGTGCGAGTGATGGAGGTGTTCCTGGCACAGTTGCGGTTGCTCTTTGGGATTGCTCAGCCCCAGCTGCC
TCCAAAATGCCTGCTTTCAGGGCCTACGAGTGAAGGGCTAATGACCTGGGAGCTAGACCGGCTGCTCTGGGCTCGGTCAGTGGAGAACCT
GGCCACAGCCACCACCACCCTTACCTCCCTGGCGCAGCTTCTGGGCAAGATCAGCAACATTGTCATTAAGGACGACGTGGCATCTGAGGT
GTACAAGGCTGTAGCTGCCGTCCAGAAGTCGGCAGAAGAGTTGGCGTCTGGGCACCTGGCATCTGCCTTTGTCGCCAGCCAGGAAGCTGT
GACATCCTCTGAGCTTGCCTTCTTTGACCCGTCACTCCTCCACCTCCTTTATTTCCCTGATGACCAGAAGTTTGCCATCTACATCCCACT
CTTCCTGCCTATGGCTGTGCCCATCCTCCTGTCCCTGGTCAAGATCTTCCTGGAGACCCGCAAGTCCTGGAGAAAGCCTGAGAAGACAGA
CTGAGCAGGGCAGCACCTCCATAGGAAGCCTTCCTTTCTGGCCAAGGTGGGCGGTGTTAGATTGTGAGGCACGTACATGGGGCCTGCCGG
AATGACTTAAATATTTGTCTCCAGTCTCCACTGTTGGCTCTCCAGCAACCAAAGTACAACACTCCAAGATGGGTTCATCTTTTCTTCCTT
TCCCATTCACCTGGCTCAATCCTCCTCCACCACCAGGGGCCTCAAAAGGCACATCATCCGGGTCTCCTTATCTTGTTTGATAAGGCTGCT
GCCTGTCTCCCTCTGTGGCAAGGACTGTTTGTTCTTTTGCCCCATTTCTCAACATAGCACACTTGTGCACTGAGAGGAGGGAGCATTATG
GGAAAGTCCCTGCCTTCCACACCTCTCTCTAGTCCCTGTGGGACAGCCCTAGCCCCTGCTGTCATGAAGGGGCCAGGCATTGGTCACCTG
TGGGACCTTCTCCCTCACTCCCCTCCCTCCTAGTTGGCTTTGTCTGTCAGGTGCAGTCTGGCGGGAGTCCAGGAGGCAGCAGCTCAGGAC
ATGGTGCTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTCAGAGGTTCCAGAAAGTTCCAGATTTGGAATCAAACAGTCCTGAAT
TCAAATCCTTGTTTTTGCACTTATTGTCTGGAGAGCTTTGGATAAGGTATTGAATCTCTCTGAGCCTCAGTTTTTCATTTGTTCAAATGG
CACTGATGATGTCTCCCTTACAAGATGGTTGTGAGGAGTAAATGTGATCAGCATGTAAAGTGTCTGGCGTGTAGTAGGCTCTTAATAAAC

>56655_56655_5_MYO1D-PIGS_MYO1D_chr17_31203796_ENST00000583621_PIGS_chr17_26897981_ENST00000308360_length(amino acids)=494AA_BP=
MVPVTVVFTRESVPLDDQEKLPFTVVHEREIPLKYKMKIKCRFQKAYRRALDHEEEALSSGSVQEAEAMLDEPQEQAEGSLTVYVISEHS
SLLPQDMMSYIGPKRTAVVRGIMHREAFNIIGRRIVQVAQAMSLTEDVLAAALADHLPEDKWSAEKRRPLKSSLGYEITFSLLNPDPKSH
DVYWDIEGAVRRYVQPFLNALGAAGNFSVDSQILYYAMLGVNPRFDSASSSYYLDMHSLPHVINPVESRLGSSAASLYPVLNFLLYVPEL
AHSPLYIQDKDGAPVATNAFHSPRWGGIMVYNVDSKTYNASVLPVRVEVDMVRVMEVFLAQLRLLFGIAQPQLPPKCLLSGPTSEGLMTW
ELDRLLWARSVENLATATTTLTSLAQLLGKISNIVIKDDVASEVYKAVAAVQKSAEELASGHLASAFVASQEAVTSSELAFFDPSLLHLL

--------------------------------------------------------------
>56655_56655_6_MYO1D-PIGS_MYO1D_chr17_31203796_ENST00000583621_PIGS_chr17_26897981_ENST00000395346_length(transcript)=2727nt_BP=400nt
AGGCTGGAGGCGGGACCAGCCGCTGCCGTCTCCGTCTCGGTGTCCCGGCCCCTACAGCGCCCGGCAGCCGCGGCGGGAGGAGCGGAAACT
GTCGGGTGCGTCCCGTTCGGAGCCGCGCCGGCCGAGAAGGCGCCGAGGAGCAGCGAGGCGGCCTCTGTCCGGCCCGGACCCGCCGAGCGG
CGTGCGCGCCCCCTCCCCGTAGCCTCGCGGCGCGGCCTCGCCCCGGCCCCTCCCGAGCTCATCGCGGGCCCACGGAGCGGCCCCGGAGGC
CCGAGCGCGCCCACCTGAGCCCCCGCGCTGGCGCCATGGCGGAGCAGGAGAGCCTGGAATTCGGCAAGGCAGACTTCGTGCTGATGGACA
CCGTCTCCATGCCCGAGTTCATGGCCAACCTCAGGCTCAGCTCCGCCTCATGGTGCCTGTCACTGTCGTGTTTACGCGGGAGTCAGTGCC
CCTGGACGACCAGGAGAAGCTGCCCTTCACCGTTGTGCATGAAAGAGAGATTCCTCTGAAATACAAAATGAAAATCAAATGCCGTTTCCA
GAAGGCCTATCGGAGGGCTTTGGACCATGAGGAGGAGGCCCTGTCATCGGGCAGTGTGCAAGAGGCAGAAGCCATGTTAGATGAGCCTCA
GGAACAAGCGGAGGGCTCCCTGACTGTGTACGTGATATCTGAACACTCCTCACTTCTTCCCCAGGACATGATGAGCTACATTGGGCCCAA
GAGGACAGCAGTGGTGCGGGGGATAATGCACCGGGAGGCCTTTAACATCATTGGCCGCCGCATAGTCCAGGTGGCCCAGGCCATGTCTTT
GACTGAGGATGTGCTTGCTGCTGCTCTGGCTGACCACCTTCCAGAGGACAAGTGGAGCGCTGAGAAGAGGCGGCCTCTCAAGTCCAGCTT
GGGCTATGAGATCACCTTCAGTTTACTCAACCCAGACCCCAAGTCCCATGATGTCTACTGGGACATTGAGGGGGCTGTCCGGCGCTATGT
GCAACCTTTCCTGAATGCCCTCGGTGCCGCTGGCAACTTCTCTGTGGACTCTCAGATTCTTTACTATGCAATGTTGGGGGTGAATCCCCG
CTTTGACTCAGCTTCCTCCAGCTACTATTTGGACATGCACAGCCTCCCCCATGTCATCAACCCAGTGGAGTCCCGGCTGGGATCCAGTGC
TGCCTCCTTGTACCCTGTGCTCAACTTTCTACTCTACGTGCCTGAGCTTGCACACTCACCGCTGTACATTCAGGACAAGGATGGCGCTCC
AGTGGCCACCAATGCCTTCCATAGTCCCCGCTGGGGTGGCATTATGGTATATAATGTTGACTCCAAAACCTATAATGCCTCAGTGCTGCC
AGTGAGAGTCGAGGTGGACATGGTGCGAGTGATGGAGGTGTTCCTGGCACAGTTGCGGTTGCTCTTTGGGATTGCTCAGCCCCAGCTGCC
TCCAAAATGCCTGCTTTCAGGGCCTACGAGTGAAGGGCTAATGACCTGGGAGCTAGACCGGCTGCTCTGGGCTCGGTCAGTGGAGAACCT
GGCCACAGCCACCACCACCCTTACCTCCCTGGCGCAGCTTCTGGGCAAGATCAGCAACATTGTCATTAAGGACGACGTGGCATCTGAGGT
GTACAAGGCTGTAGCTGCCGTCCAGAAGTCGGCAGAAGAGTTGGCGTCTGGGCACCTGGCATCTGCCTTTGTCGCCAGCCAGGAAGCTGT
GACATCCTCTGAGCTTGCCTTCTTTGACCCGTCACTCCTCCACCTCCTTTATTTCCCTGATGACCAGAAGTTTGCCATCTACATCCCACT
CTTCCTGCCTATGGCTGTGCCCATCCTCCTGTCCCTGGTCAAGATCTTCCTGGAGACCCGCAAGTCCTGGAGAAAGCCTGAGAAGACAGA
CTGAGCAGGGCAGCACCTCCATAGGAAGCCTTCCTTTCTGGCCAAGGTGGGCGGTGTTAGATTGTGAGGCACGTACATGGGGCCTGCCGG
AATGACTTAAATATTTGTCTCCAGTCTCCACTGTTGGCTCTCCAGCAACCAAAGTACAACACTCCAAGATGGGTTCATCTTTTCTTCCTT
TCCCATTCACCTGGCTCAATCCTCCTCCACCACCAGGGGCCTCAAAAGGCACATCATCCGGGTCTCCTTATCTTGTTTGATAAGGCTGCT
GCCTGTCTCCCTCTGTGGCAAGGACTGTTTGTTCTTTTGCCCCATTTCTCAACATAGCACACTTGTGCACTGAGAGGAGGGAGCATTATG
GGAAAGTCCCTGCCTTCCACACCTCTCTCTAGTCCCTGTGGGACAGCCCTAGCCCCTGCTGTCATGAAGGGGCCAGGCATTGGTCACCTG
TGGGACCTTCTCCCTCACTCCCCTCCCTCCTAGTTGGCTTTGTCTGTCAGGTGCAGTCTGGCGGGAGTCCAGGAGGCAGCAGCTCAGGAC
ATGGTGCTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTCAGAGGTTCCAGAAAGTTCCAGATTTGGAATCAAACAGTCCTGAAT
TCAAATCCTTGTTTTTGCACTTATTGTCTGGAGAGCTTTGGATAAGGTATTGAATCTCTCTGAGCCTCAGTTTTTCATTTGTTCAAATGG
CACTGATGATGTCTCCCTTACAAGATGGTTGTGAGGAGTAAATGTGATCAGCATGTAAAGTGTCTGGCGTGTAGTAGGCTCTTAATAAAC

>56655_56655_6_MYO1D-PIGS_MYO1D_chr17_31203796_ENST00000583621_PIGS_chr17_26897981_ENST00000395346_length(amino acids)=494AA_BP=
MVPVTVVFTRESVPLDDQEKLPFTVVHEREIPLKYKMKIKCRFQKAYRRALDHEEEALSSGSVQEAEAMLDEPQEQAEGSLTVYVISEHS
SLLPQDMMSYIGPKRTAVVRGIMHREAFNIIGRRIVQVAQAMSLTEDVLAAALADHLPEDKWSAEKRRPLKSSLGYEITFSLLNPDPKSH
DVYWDIEGAVRRYVQPFLNALGAAGNFSVDSQILYYAMLGVNPRFDSASSSYYLDMHSLPHVINPVESRLGSSAASLYPVLNFLLYVPEL
AHSPLYIQDKDGAPVATNAFHSPRWGGIMVYNVDSKTYNASVLPVRVEVDMVRVMEVFLAQLRLLFGIAQPQLPPKCLLSGPTSEGLMTW
ELDRLLWARSVENLATATTTLTSLAQLLGKISNIVIKDDVASEVYKAVAAVQKSAEELASGHLASAFVASQEAVTSSELAFFDPSLLHLL

--------------------------------------------------------------

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Fusion Gene PPI Analysis for MYO1D-PIGS


check button Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in

ChiPPI page.


check button Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160)
HgeneHgene's interactorsTgeneTgene's interactors


check button - Retained PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenStill interaction with


check button - Lost PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


check button - Retained PPIs, but lost function due to frame-shift fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


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Related Drugs for MYO1D-PIGS


check button Drugs targeting genes involved in this fusion gene.
(DrugBank Version 5.1.8 2021-05-08)
PartnerGeneUniProtAccDrugBank IDDrug nameDrug activityDrug typeDrug status

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Related Diseases for MYO1D-PIGS


check button Diseases associated with fusion partners.
(DisGeNet 4.0)
PartnerGeneDisease IDDisease name# pubmedsSource