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Center for Computational Systems Medicine
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Fusion Gene Summary

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Fusion Gene ORF analysis

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Fusion Genomic Features

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Fusion Protein Features

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Fusion Gene Sequence

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Fusion Gene PPI analysis

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Related Drugs

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Related Diseases

Fusion gene:MYO5A-DCBLD2 (FusionGDB2 ID:56706)

Fusion Gene Summary for MYO5A-DCBLD2

check button Fusion gene summary
Fusion gene informationFusion gene name: MYO5A-DCBLD2
Fusion gene ID: 56706
HgeneTgene
Gene symbol

MYO5A

DCBLD2

Gene ID

4644

131566

Gene namemyosin VAdiscoidin, CUB and LCCL domain containing 2
SynonymsGS1|MYH12|MYO5|MYR12CLCP1|ESDN
Cytomap

15q21.2

3q12.1|3

Type of geneprotein-codingprotein-coding
Descriptionunconventional myosin-Vadilute myosin heavy chain, non-musclemyosin Vmyosin VA (heavy chain 12, myoxin)myosin, heavy polypeptide kinasemyosin-12myosin-Vamyoxindiscoidin, CUB and LCCL domain-containing protein 21700055P21RikCUB, LCCL and coagulation factor V/VIII-homology domains protein 1coagulation factor V/VIII-homology domains protein 1endothelial and smooth muscle cell-derived neuropilin-like protein
Modification date2020031320200313
UniProtAcc

Q9Y4I1

Q96PD2

Ensembl transtripts involved in fusion geneENST00000356338, ENST00000358212, 
ENST00000399231, ENST00000399233, 
ENST00000553916, 		ENST00000469648, 
ENST00000326840, ENST00000326857, 
Fusion gene scores* DoF score13 X 13 X 6=10146 X 6 X 4=144
# samples 127
** MAII scorelog2(12/1014*10)=-3.07895134139482
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0		log2(7/144*10)=-1.04064198449735
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0
Context

PubMed: MYO5A [Title/Abstract] AND DCBLD2 [Title/Abstract] AND fusion [Title/Abstract]

Most frequent breakpointMYO5A(52599483)-DCBLD2(98520493), # samples:1
Anticipated loss of major functional domain due to fusion event.MYO5A-DCBLD2 seems lost the major protein functional domain in Hgene partner, which is a CGC due to the frame-shifted ORF.
MYO5A-DCBLD2 seems lost the major protein functional domain in Hgene partner, which is a essential gene due to the frame-shifted ORF.
* DoF score (Degree of Frequency) = # partners X # break points X # cancer types
** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)

check button Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez
PartnerGeneGO IDGO termPubMed ID
TgeneDCBLD2

GO:0030308

negative regulation of cell growth

11447234

TgeneDCBLD2

GO:0042060

wound healing

11447234


check buttonFusion gene breakpoints across MYO5A (5'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check buttonFusion gene breakpoints across DCBLD2 (3'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check button Fusion gene information from two resources (ChiTars 5.0 and ChimerDB 4.0)
* All genome coordinats were lifted-over on hg19.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
SourceDiseaseSampleHgeneHchrHbpHstrandTgeneTchrTbpTstrand
ChimerDB4SKCMTCGA-D9-A149-06AMYO5Achr15

52599483

-DCBLD2chr3

98520493

-


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Fusion Gene ORF analysis for MYO5A-DCBLD2

check button Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
ORFHenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrand
5CDS-intronENST00000356338ENST00000469648MYO5Achr15

52599483

-DCBLD2chr3

98520493

-
5CDS-intronENST00000358212ENST00000469648MYO5Achr15

52599483

-DCBLD2chr3

98520493

-
5CDS-intronENST00000399231ENST00000469648MYO5Achr15

52599483

-DCBLD2chr3

98520493

-
5CDS-intronENST00000399233ENST00000469648MYO5Achr15

52599483

-DCBLD2chr3

98520493

-
Frame-shiftENST00000358212ENST00000326840MYO5Achr15

52599483

-DCBLD2chr3

98520493

-
Frame-shiftENST00000358212ENST00000326857MYO5Achr15

52599483

-DCBLD2chr3

98520493

-
Frame-shiftENST00000399233ENST00000326840MYO5Achr15

52599483

-DCBLD2chr3

98520493

-
Frame-shiftENST00000399233ENST00000326857MYO5Achr15

52599483

-DCBLD2chr3

98520493

-
In-frameENST00000356338ENST00000326840MYO5Achr15

52599483

-DCBLD2chr3

98520493

-
In-frameENST00000356338ENST00000326857MYO5Achr15

52599483

-DCBLD2chr3

98520493

-
In-frameENST00000399231ENST00000326840MYO5Achr15

52599483

-DCBLD2chr3

98520493

-
In-frameENST00000399231ENST00000326857MYO5Achr15

52599483

-DCBLD2chr3

98520493

-
intron-3CDSENST00000553916ENST00000326840MYO5Achr15

52599483

-DCBLD2chr3

98520493

-
intron-3CDSENST00000553916ENST00000326857MYO5Achr15

52599483

-DCBLD2chr3

98520493

-
intron-intronENST00000553916ENST00000469648MYO5Achr15

52599483

-DCBLD2chr3

98520493

-

check buttonORFfinder result based on the fusion transcript sequence of in-frame fusion genes.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandSeq length
(transcript)		BP loci
(transcript)		Predicted start
(transcript)		Predicted stop
(transcript)		Seq length
(amino acids)
ENST00000399231MYO5Achr1552599483-ENST00000326840DCBLD2chr398520493-163141222524458111855
ENST00000399231MYO5Achr1552599483-ENST00000326857DCBLD2chr398520493-145141222524458111855
ENST00000356338MYO5Achr1552599483-ENST00000326840DCBLD2chr398520493-16060119717455601828
ENST00000356338MYO5Achr1552599483-ENST00000326857DCBLD2chr398520493-14260119717455601828

check buttonDeepORF prediction of the coding potential based on the fusion transcript sequence of in-frame fusion genes. DeepORF is a coding potential classifier based on convolutional neural network by comparing the real Ribo-seq data. If the no-coding score < 0.5 and coding score > 0.5, then the in-frame fusion transcript is predicted as being likely translated.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandNo-coding scoreCoding score
ENST00000399231ENST00000326840MYO5Achr1552599483-DCBLD2chr398520493-0.0001098230.9998902
ENST00000399231ENST00000326857MYO5Achr1552599483-DCBLD2chr398520493-0.0001641740.99983585
ENST00000356338ENST00000326840MYO5Achr1552599483-DCBLD2chr398520493-0.0001217270.9998783
ENST00000356338ENST00000326857MYO5Achr1552599483-DCBLD2chr398520493-0.0001782850.9998217

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Fusion Genomic Features for MYO5A-DCBLD2


check buttonFusionAI prediction of the potential fusion gene breakpoint based on the pre-mature RNA sequence context (+/- 5kb of individual partner genes, total 20kb length sequence). FusionAI is a fusion gene breakpoint classifier based on convolutional neural network by comparing the fusion positive and negative sequence context of ~ 20K fusion gene data. From here, we can have the relative potentency of the 20K genomic sequence how individual sequnce will be likely used as the gene fusion breakpoints.
HgeneHchrHbpHstrandTgeneTchrTbpTstrand1-pp (fusion gene breakpoint)

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions. We integrated a total of 44 different types of human genomic feature loci information across five big categories including virus integration sites, repeats, structural variants, chromatin states, and gene expression regulation. More details are in help page.
genomic feature

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions that are ovelapped with the top 1% feature importance score regions. More details are in help page.

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Fusion Protein Features for MYO5A-DCBLD2


check button Four levels of functional features of fusion genes
Go to FGviewer search page for the most frequent breakpoint (https://ccsmweb.uth.edu/FGviewer/chr15:52599483/chr3:98520493)
- FGviewer provides the online visualization of the retention search of the protein functional features across DNA, RNA, protein, and pathological levels.
- How to search
1. Put your fusion gene symbol.
2. Press the tab key until there will be shown the breakpoint information filled.
4. Go down and press 'Search' tab twice.
4. Go down to have the hyperlink of the search result.
5. Click the hyperlink.
6. See the FGviewer result for your fusion gene.
FGviewer

check buttonMain function of each fusion partner protein. (from UniProt)
HgeneTgene
MYO5A

Q9Y4I1

DCBLD2

Q96PD2

FUNCTION: Processive actin-based motor that can move in large steps approximating the 36-nm pseudo-repeat of the actin filament. Involved in melanosome transport. Also mediates the transport of vesicles to the plasma membrane. May also be required for some polarization process involved in dendrite formation. {ECO:0000269|PubMed:10448864}.

check buttonRetention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at

download page


* Minus value of BPloci means that the break pointn is located before the CDS.
- In-frame and retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneMYO5Achr15:52599483chr3:98520493ENST00000356338-40401338_144539651829.0Coiled coilOntology_term=ECO:0000255
HgeneMYO5Achr15:52599483chr3:98520493ENST00000356338-4040914_123739651829.0Coiled coilOntology_term=ECO:0000255
HgeneMYO5Achr15:52599483chr3:98520493ENST00000399231-41411338_144539931856.0Coiled coilOntology_term=ECO:0000255
HgeneMYO5Achr15:52599483chr3:98520493ENST00000399231-4141914_123739931856.0Coiled coilOntology_term=ECO:0000255
HgeneMYO5Achr15:52599483chr3:98520493ENST00000356338-40401534_181039651829.0DomainDilute
HgeneMYO5Achr15:52599483chr3:98520493ENST00000356338-404069_76339651829.0DomainMyosin motor
HgeneMYO5Achr15:52599483chr3:98520493ENST00000356338-4040766_78839651829.0DomainIQ 1
HgeneMYO5Achr15:52599483chr3:98520493ENST00000356338-4040789_81839651829.0DomainIQ 2
HgeneMYO5Achr15:52599483chr3:98520493ENST00000356338-4040814_83639651829.0DomainIQ 3
HgeneMYO5Achr15:52599483chr3:98520493ENST00000356338-4040837_86139651829.0DomainIQ 4
HgeneMYO5Achr15:52599483chr3:98520493ENST00000356338-4040862_88339651829.0DomainIQ 5
HgeneMYO5Achr15:52599483chr3:98520493ENST00000356338-4040885_91439651829.0DomainIQ 6
HgeneMYO5Achr15:52599483chr3:98520493ENST00000356338-40408_6039651829.0DomainMyosin N-terminal SH3-like
HgeneMYO5Achr15:52599483chr3:98520493ENST00000399231-41411534_181039931856.0DomainDilute
HgeneMYO5Achr15:52599483chr3:98520493ENST00000399231-414169_76339931856.0DomainMyosin motor
HgeneMYO5Achr15:52599483chr3:98520493ENST00000399231-4141766_78839931856.0DomainIQ 1
HgeneMYO5Achr15:52599483chr3:98520493ENST00000399231-4141789_81839931856.0DomainIQ 2
HgeneMYO5Achr15:52599483chr3:98520493ENST00000399231-4141814_83639931856.0DomainIQ 3
HgeneMYO5Achr15:52599483chr3:98520493ENST00000399231-4141837_86139931856.0DomainIQ 4
HgeneMYO5Achr15:52599483chr3:98520493ENST00000399231-4141862_88339931856.0DomainIQ 5
HgeneMYO5Achr15:52599483chr3:98520493ENST00000399231-4141885_91439931856.0DomainIQ 6
HgeneMYO5Achr15:52599483chr3:98520493ENST00000399231-41418_6039931856.0DomainMyosin N-terminal SH3-like
HgeneMYO5Achr15:52599483chr3:98520493ENST00000356338-4040163_17039651829.0Nucleotide bindingATP
HgeneMYO5Achr15:52599483chr3:98520493ENST00000399231-4141163_17039931856.0Nucleotide bindingATP
HgeneMYO5Achr15:52599483chr3:98520493ENST00000356338-4040643_66539651829.0RegionActin-binding
HgeneMYO5Achr15:52599483chr3:98520493ENST00000399231-4141643_66539931856.0RegionActin-binding

- In-frame and not-retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
TgeneDCBLD2chr15:52599483chr3:98520493ENST000003268401216463_466556776.0Compositional biasNote=Poly-Pro
TgeneDCBLD2chr15:52599483chr3:98520493ENST000003268571216463_466556790.0Compositional biasNote=Poly-Pro
TgeneDCBLD2chr15:52599483chr3:98520493ENST000003268401216187_285556776.0DomainLCCL
TgeneDCBLD2chr15:52599483chr3:98520493ENST00000326840121672_186556776.0DomainCUB
TgeneDCBLD2chr15:52599483chr3:98520493ENST000003268571216187_285556790.0DomainLCCL
TgeneDCBLD2chr15:52599483chr3:98520493ENST00000326857121672_186556790.0DomainCUB
TgeneDCBLD2chr15:52599483chr3:98520493ENST000003268401216550_775556776.0Topological domainCytoplasmic
TgeneDCBLD2chr15:52599483chr3:98520493ENST00000326840121667_528556776.0Topological domainExtracellular
TgeneDCBLD2chr15:52599483chr3:98520493ENST000003268571216550_775556790.0Topological domainCytoplasmic
TgeneDCBLD2chr15:52599483chr3:98520493ENST00000326857121667_528556790.0Topological domainExtracellular
TgeneDCBLD2chr15:52599483chr3:98520493ENST000003268401216529_549556776.0TransmembraneHelical
TgeneDCBLD2chr15:52599483chr3:98520493ENST000003268571216529_549556790.0TransmembraneHelical


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Fusion Gene Sequence for MYO5A-DCBLD2


check button For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. To have fusion amino acid sequence, we ran ORFfinder and chose the longest ORF among the all predicted ones.
>56706_56706_1_MYO5A-DCBLD2_MYO5A_chr15_52599483_ENST00000356338_DCBLD2_chr3_98520493_ENST00000326840_length(transcript)=16060nt_BP=11971nt
AGTCCGCTCGGGCGGCCGCCCAGGCGAGGTGCGGCCTCCGCACAGGCGGGGGGCGTAGGCGCGCGGGGCCCGCCATGGCTGCGTCGGAGC
TCTACACAAAGTTTGCCAGGGTTTGGATACCTGATCCAGAGGAAGTCTGGAAGTCAGCAGAGCTGCTCAAAGATTATAAGCCAGGAGATA
AAGTCCTCCTGCTTCACCTCGAGGAAGGAAAGGATTTGGAATACCATCTAGATCCAAAGACCAAGGAGCTGCCTCACTTACGAAATCCTG
ACATACTTGTTGGTGAAAATGACCTCACAGCCCTCAGCTATCTTCATGAGCCTGCTGTGCTCCATAATCTCAGAGTCCGCTTTATTGATT
CCAAACTTATTTATACGTATTGTGGTATAGTCCTAGTAGCTATAAATCCCTATGAACAGCTGCCTATTTATGGAGAAGATATTATTAATG
CATACAGTGGTCAGAACATGGGTGATATGGATCCACATATCTTTGCAGTAGCTGAAGAAGCTTACAAGCAAATGGCCAGAGATGAACGAA
ATCAGTCCATCATCGTAAGTGGAGAGTCTGGGGCAGGAAAAACAGTCTCAGCTAAGTATGCCATGCGATACTTTGCAACTGTGAGTGGTT
CTGCCAGTGAGGCCAATGTGGAGGAAAAGGTCTTGGCCTCCAACCCCATCATGGAGTCCATTGGAAATGCTAAAACAACCAGGAATGATA
ATAGCAGCCGTTTTGGGAAGTATATTGAGATTGGTTTTGATAAGAGATATCGAATCATTGGTGCCAATATGAGAACTTATCTTTTAGAGA
AATCCAGAGTGGTATTCCAGGCAGAAGAGGAGAGAAACTATCATATCTTCTATCAGCTTTGTGCCTCAGCAAAGTTACCTGAATTTAAAA
TGCTACGATTAGGAAATGCAGATAACTTTAATTACACAAAACAAGGAGGCAGTCCTGTGATTGAAGGAGTGGATGATGCAAAGGAGATGG
CACATACTAGGCAGGCCTGCACTTTGCTAGGAATTAGTGAATCTCATCAAATGGGAATTTTCCGAATACTTGCTGGCATCCTTCACTTAG
GCAATGTTGGATTTACATCCCGAGATGCAGACAGCTGCACAATACCTCCCAAGCATGAACCTCTCTGCATCTTCTGTGAACTCATGGGTG
TGGACTATGAGGAGATGTGTCACTGGCTCTGCCATCGGAAACTGGCTACTGCCACAGAGACATACATCAAGCCCATCTCCAAGCTGCAGG
CCACAAATGCCCGCGATGCTTTGGCCAAGCACATCTATGCCAAGCTCTTTAACTGGATTGTAGATAATGTCAATCAGGCTCTCCATTCTG
CTGTCAAACAGCACTCTTTTATTGGTGTGCTAGACATTTACGGATTTGAAACATTTGAGATAAATAGTTTTGAACAGTTTTGCATAAATT
ATGCAAATGAAAAACTACAGCAACAATTCAATATGCATGTCTTCAAATTGGAGCAAGAAGAATATATGAAGGAACAAATTCCATGGACAC
TCATAGATTTTTATGATAATCAGCCTTGTATTAATCTTATAGAATCAAAACTAGGCATTCTAGATTTACTGGATGAGGAATGCAAGATGC
CTAAAGGCACAGATGACACCTGGGCCCAAAAATTGTACAACACACATTTGAACAAATGTGCACTCTTTGAAAAGCCTCGTCTATCAAACA
AAGCTTTCATCATCCAACATTTTGCTGACAAAGTGGAATACCAGTGTGAAGGATTTCTCGAAAAGAATAAAGACACCGTTTTTGAAGAAC
AAATTAAAGTTCTTAAATCAAGCAAGTTTAAGATGCTACCAGAACTATTTCAAGATGATGAGAAGGCCATCAGTCCAACTTCAGCCACCT
CCTCAGGGCGCACACCCCTCACACGAACTCCTGCAAAGCCCACCAAAGGCAGACCAGGCCAAATGGCCAAAGAGCACAAGAAAACAGTGG
GGCATCAGTTCAGAAACTCCCTGCACCTGCTTATGGAGACACTCAATGCCACTACCCCTCACTATGTGCGCTGTATCAAGCCTAATGACT
TCAAGTTCCCATTCACGTTTGATGAGAAGAGGGCAGTGCAGCAGCTGAGAGCATGTGGTGTCCTGGAAACCATCCGAATCAGTGCGGCCG
GTTTCCCCTCACGGTGGACTTACCAAGAATTTTTCAGCCGCTACCGTGTCCTAATGAAGCAGAAAGATGTGCTGAGTGACAGAAAGCAAA
CATGCAAGAATGTGTTAGAGAAACTGATACTGGACAAGGACAAATACCAGTTTGGTAAGACAAAGATCTTTTTCCGTGCCGGTCAAGTGG
CCTATCTAGAAAAATTGAGAGCTGACAAACTGAGAGCTGCCTGCATCCGGATCCAGAAGACCATCCGAGGGTGGCTGCTGAGAAAGAAGT
ACCTACGCATGCGGAAGGCAGCCATCACCATGCAGAGATACGTGCGGGGCTACCAGGCCCGATGCTATGCTAAGTTTCTGCGCAGAACCA
AGGCAGCAACCATCATTCAAAAGTACTGGCGCATGTATGTGGTCCGCAGGAGGTACAAGATTAGACGAGCTGCCACTATCGTTCTTCAGT
CTTACTTGCGAGGCTTCTTGGCCAGAAATAGGTATCGCAAGATACTCCGTGAGCACAAAGCAGTCATCATTCAGAAGCGAGTCCGGGGCT
GGCTGGCCCGCACACACTACAAGAGGAGCATGCATGCCATCATCTACCTTCAGTGCTGCTTCAGGCGGATGATGGCCAAGCGTGAGCTAA
AGAAGCTCAAAATCGAGGCTCGCTCAGTGGAGCGCTATAAGAAGCTGCACATCGGCATGGAGAACAAGATCATGCAGCTGCAGCGCAAAG
TTGATGAGCAGAACAAAGACTACAAATGCCTTGTGGAGAAACTAACCAATCTGGAAGGAATATACAACTCTGAGACTGAGAAACTACGAA
GTGACTTAGAACGTCTTCAACTAAGTGAAGAGGAAGCGAAAGTTGCCACTGGGCGGGTCCTTAGTCTGCAGGAAGAAATTGCCAAGCTCC
GGAAAGACCTGGAGCAAACTCGTTCAGAGAAAAAATGCATTGAGGAACATGCAGATCGATACAAACAAGAAACAGAGCAGCTGGTATCAA
ATCTGAAGGAAGAAAATACTTTGCTGAAGCAAGAAAAAGAAGCCCTCAATCACCGCATCGTGCAGCAGGCTAAGGAGATGACAGAAACTA
TGGAGAAGAAGTTAGTAGAAGAAACGAAACAACTGGAACTCGACCTTAATGATGAAAGGCTGAGATATCAGAACCTTCTGAATGAGTTCA
GTCGCCTGGAAGAAAGATATGATGACCTCAAGGAAGAGATGACCCTTATGGTGCATGTGCCTAAGCCTGGACACAAGAGAACAGACTCCA
CCCACAGCAGCAACGAGTCTGAATATATCTTTAGCTCTGAAATTGCAGAAATGGAAGACATTCCATCAAGGACAGAGGAACCAAGTGAGA
AGAAGGTACCTCTGGACATGTCATTGTTCCTTAAGCTCCAGAAGCGGGTCACAGAGCTGGAGCAGGAGAAGCAGGTGATGCAGGATGAGC
TGGACCGCAAGGAGGAGCAGGTGCTCCGCAGCAAGGCCAAGGAAGAAGAAAGACCACAAATTAGAGGTGCAGAACTGGAATATGAGTCAC
TCAAGCGTCAAGAACTAGAATCAGAAAACAAAAAACTGAAGAATGAGCTAAATGAGTTGCGCAAGGCCCTCAGTGAGAAAAGTGCCCCAG
AGGTGACCGCCCCAGGTGCACCTGCCTACCGTGTCCTCATGGAGCAGCTGACCTCTGTGAGCGAGGAGCTTGATGTCCGCAAGGAGGAAG
TCCTCATCTTAAGGTCTCAACTGGTGAGCCAGAAAGAGGCCATCCAACCCAAGGATGACAAGAATACAATGACAGATTCCACAATACTTT
TGGAAGATGTACAAAAAATGAAAGATAAAGGTGAAATAGCACAAGCATACATTGGTTTGAAAGAAACAAATAGGCTCCTGGAATCCCAGC
TGCAGTCACAGAAGAGGAGCCATGAGAATGAGGCCGAGGCCCTCCGTGGGGAGATCCAGAGCCTGAAGGAGGAGAACAACCGACAGCAGC
AGCTGCTGGCCCAGAACCTGCAGCTGCCCCCAGAGGCCCGCATTGAGGCCAGCCTGCAGCACGAGATCACCCGGCTGACCAACGAAAACT
TGGATTTGATGGAACAACTTGAAAAACAGGATAAGACGGTCCGTAAACTGAAAAAACAACTGAAAGTATTTGCCAAAAAAATTGGCGAAC
TAGAAGTGGGCCAGATGGAGAACATATCCCCAGGACAGATCATTGATGAACCCATCCGACCAGTCAACATTCCCAGGAAAGAAAAGGATT
TCCAAGGGATGCTGGAATACAAGAAGGAGGATGAGCAAAAACTTGTTAAGAACCTGATTCTGGAACTGAAGCCACGTGGTGTAGCAGTCA
ATTTGATTCCAGGATTACCGGCATATATCCTGTTCATGTGTGTTCGACATGCTGACTACCTGAATGATGATCAGAAAGTAAGGTCGTTGC
TAACATCAACAATTAACAGCATCAAAAAAGTATTGAAGAAAAGAGGTGATGATTTTGAAACCGTCTCCTTCTGGCTCTCTAACACATGCC
GATTTTTGCACTGCTTGAAACAGTACAGTGGAGAAGAGGGCTTTATGAAGCACAACACATCTCGCCAGAATGAACACTGCCTCACCAATT
TTGACCTGGCTGAGTATCGGCAGGTGCTGAGTGACTTGGCCATTCAGATCTACCAGCAGCTCGTGCGGGTGTTAGAGAACATCCTTCAGC
CAATGATTGTCTCAGGCATGCTGGAACATGAAACGATTCAGGGCGTGTCTGGGGTGAAGCCCACAGGGTTGAGAAAGCGAACCTCCAGTA
TCGCCGATGAGGGCACCTACACACTGGACTCCATCCTCCGGCAGCTCAACTCCTTCCACTCGGTCATGTGTCAGCATGGCATGGACCCTG
AACTGATCAAGCAGGTGGTCAAGCAGATGTTCTACATCATAGGGGCCATCACCCTGAACAACCTTCTCCTGCGGAAGGACATGTGCTCCT
GGAGTAAAGGCATGCAGATCAGGTACAATGTCAGTCAACTGGAAGAATGGCTGCGTGACAAGAATCTGATGAATAGTGGGGCTAAAGAAA
CCCTGGAACCTCTCATTCAGGCTGCTCAACTTTTGCAAGTGAAAAAGAAAACAGATGATGATGCAGAAGCCATTTGTTCTATGTGCAATG
CTTTAACTACTGCCCAGATTGTGAAAGTGTTGAATTTGTATACTCCAGTTAATGAGTTTGAAGAAAGAGTCTCTGTGTCGTTCATTCGTA
CTATACAGATGCGTTTACGAGACAGGAAAGACTCTCCCCAGCTGCTCATGGATGCTAAACACATCTTTCCTGTCACCTTTCCTTTCAACC
CATCTTCCCTCGCACTAGAAACCATCCAGATTCCAGCCAGCCTCGGCCTGGGCTTCATTTCACGGGTCTGAAAGTGATGTCCAGGCAAAA
ATTGACAATACATTTCTTGCCCGAAATAAGAACCCATTATTTCCAGTGAGTTACTGAAAATACATTTTTAAAGAGAAAGTACTGATTATC
TCCCAAATGAGAAGTCATTAACTGGAAATCTCCCTAGAATACTTTCATCACTTTGGAAACAAAGATAGGCTCTTTCGTGCTGTGTTATCT
TTATAGCAACACTCATCCTTAACCAACTAGGTACCGTGAGTTTACATACAGGAGAATGATGGAAGGAAGGGAGGAAGGAAAGGAGGAGAA
AAATGTGTCTTCAGCTGGCAGCATTTATTTTAAATCCTTAGCACTGAGTTTGAATGGTATAAAAAGTATAACTTCCATAGATGAGCTGTT
GTTAGGAAGGCACCAAAGAACCTCCTCTGCACTAAACAGGAGAATGGAAAGAAAAGTCTCCATTGAGTACATATCATGTCAGTTTAGTAA
TCAATTATGTTGATATTGTTAAACTGGTTCAAAGAAATAAACTGGCAATATGTAAAGTAATTCCTCATTTGTGTCACTATGATATAGAGA
TATTAAAGGAATGTTGGTTTGCTAAATAGTATAGATGTCCATTTGTACTATAGTTTACTGAGCATTTTAAATTGCTGCTACATACTGTCT
TCTTAAAATGTAAGTGATATTAGGCACTACAATAAGTTTCTCTTGTCAATTCTGTTTACAATTCAATCAGATCACAGTTTTAACTGGATT
ATATGCAAATACCTACAGATTCACCTGCACAAGTAGCAGACACTGGAAAGTCATGTAGTAATATGACAAAATGCTTGACATTTAGGGGTA
GGATTAGACAAAGTGGCTATTGTTGATGTCATTATTTATTCAGGATGTATTACATTGATGTGCTCATTAATTTTCCCTGGGTGGATATTG
CGTCAGGGTACAGTGTTCTGTGAAGTGACTTATTTTTAACTACCAGATCTGATTCCTTCAGTGCATATTTTCAACCTTGACAGGTTTTCT
CTCTTCTTAATTTATTAAGAATTAATCTCGGCTGGGCGCGGTGGCTCACGCCTGTAATCCCAGCACTTTGGGAAGCCAAGGTGGGCGGAT
CACTTCAGGTTAGGAGTTGGAGACCAGCCTGGCCAACATGGCGAAACCCTGTCTCTACTAAAAATACAAAAATTAGCCGGGCGTGGTGGC
ACTTGCCTGTAATCCCAGCTACTCGGGAGGCTGAGGCACGAGAATCGATTAAACCTGGGAGGCGGAGATTGCAATGAGATCGAACCACTG
CACTCCAGCCTGGGTGACAGAGAGAGACACTGCCTTGGAAAAAAAAAGAATCTCACTCACTATCTAGAGAGGATTGTCAGAATATTCACG
ATTCAGGTCTTGAAACTTTGATTATGCAAAAGAAGGTATATAATAAATATTTCATTATGATTCAGTTTTTAAGGCTTTGCAGCTTCTATA
AGTGTTCTCAGATGCCACTAGATAATTTTAAAAGCATCATATTAGAAATACTTTAAGAAGACTTATATAAGAAATAGAAGATTGTTGAAT
TTTACAGAGGATTTGGTTCATTAAGACCCAGATTCTGTAAGTTTTCATTCTGAAATTCTAGTTAAACATATTCACCATTTTTCTTAGGAA
TCTTATACAATAAATCCTTCAGGTTGCACAAAAGCAAATTATTAGTTTTCATTAGAAACTCTGGTTCTGAATTACAATCATAGGTTATAT
AAATTTAACTGTTAGATGGTCTATAAATCTTATTAAAATATGTGCAATATTTATGGAAGTCAAACAGCTTCATATCAGTGATAAAGATTG
TTATTAAAAGATAAATACTGTCTGTTAATTTACATGGGCCTCAAGTTCCTCGTTTATAAAATAAGAGAGTTGGACACTGATTCTTAACAT
CTCCTCCACATTTAAAATTCTCTCTTCTCAGCCCTTAGATTCTAGAGAGAAAAAGCTGCAGTTACTCAGTAAGTCCATTCTCTGATGGAA
AGACCAGTGTGTAGTGCCTGTCAATTCCTTAGGATTAATCAAATGTAAAATCACAAGTTTGTGTAGCTGTAACCTTTCTTAAATGTACAT
GATTTATGTACATGCTTTTAGAAGGTCCTACTATATTTGTATTATAATTAGTTTAAGTAATTTTTATTACATCATGTATTGCTTTATTCA
GTTTGAATACATTTATTTATTTATTTGCAGTATCAACCAGAAACACTACCAATTGCATCAAATTCTCCCAGTTTTTCCTGGTTGTCAATG
CGGTTTTCAATGCACAATTAAGTCATAGCCATTTGGTTCGTACCAAATGTGTCAGAATCTAACAGCATCCGATAGGCTGTAAGTTGGGGA
GTTGCTAAGAAAATGCAACGTGGTACAGGCTGTCCGCCTCAGCCCTGGAAATCTCCCAGACCTCCCCCAGCTTCATCCTGTGTAGCACGA
CTCAACGTGCACCCTGAATCTTCTCAGGTCTTCCAGGTCATGCTGTAGCTGTCACTGCCATGCAGCCCTTTTTTTTACTCCGGACAGCTC
ATGTACTGAAGCGTCATGAAAGAAAGGCTGTGGTCTGAGCCCTTCTCTCCCATCTCCTGTCTTTGTCCTGTCAAGTGCTGGAGCCAGAGC
TCCTACAGCTGCCCTTGGTGGTTTCTCCTGTTCAGCGATGGTGGCACAAAGGTTCTGCTATTCCAGGGCTCCAGCTTCCTCCCAGGTCTA
CCCAGAGCTCCAGATGGGGGTCTGAATTAACCTCTCTTGGTGGCCTGGAGATTTTTAGTCATTGACAAGAATACCTTGTAACCAGGGAAC
CCCAAGGCCCAGTAAATGATTCTGTATACCATTTTCTTGAAGGTACAAGAAGATTCTGCCGACTATGGGGATCTTTGGGCCAGTTTGAGG
ATTGCTTTCCCTCTGAGGTTCTTTCTCTCTGTCAGCCACACTTTCTCACCCAACTTCAGACACACCCTGCCAGCCTTTCCCCTACTCATT
CACTCTTCCCCTTCCCTCAACTTAATCGTCTATCCCGTTGCCTGCTGTTTGACTGTGCACTGAAGGCAGGTGGATGGAGTCAGTCCTCAG
TTGCCCCTGCTGGCCTTCCTGGTGCTTACCATCAGCCCAATCTTTGCACAGTCCTTGTTGTTCTTACTTCTCTGCATGCATTCCTTCAGA
AGATCAGTCATCAACTTTTTCTTAATTCCTCTGTGACACACAATGGGAATTCAAAGGAAGAGATCTTAAAAGTCACAACAGTTCTTTATC
TTAATAATCCCCTCCCCATTCACCTTACTACATGCAGACTCACCTCACACCCTTACAACTTGAAGCTGAAAATTTAAAAGTAATTTCCCT
TTTTGCAGCTTTTCCTCAGGTTAAGGCTTTGATCTGCCTGAGAGTAACTCTAAAAGGAGGGAAGATAAATATGGGATAAAATCCACAAAG
TGTAGCTTCTAATTCCTTTGGAAGTTTAAAAAATTTCCACATATCTGATGCTTCTTTTGTCAGGTGCAGAAGCACAAAAACATATTCCGA
AGCCAACTGATAGGGAATTTGGGGATTATTGTCAGTTTGGAGAATTTGCTGTGTTATTTCTTCATTTCCATGGATAGCTCATAGTTGGCT
CTTTCTGGGTGAGTAATTATGTGTAATATAGATCAAATCTTTTACTAAGGTTACAGCTACATGTTAGGGGAGGCTATGAAAATACTATAT
TATTATAATTTCAGTGCAGTGATTGTTGTGAGAAATAACTTTCATGGTAACCCTAGGAAAATGGGCACCTGCCACCATCCTGAGAAGTCC
TCACACAATGCCCTTTCTCTCTTACACACACACACACACACATACACACACACACACCCCCGTCACTAATTCATAGAGTTCCTTAGCAGG
CATAGTCAAGGATCCTCTGGGTAATGTCAGCTGCTTAGTGATAAAACAGAGCCAAAACTAGTGCATCCTGTTGAAAGTAATGCAGAAACA
GTACCTGGGTCCAGATATGCTTTCCTGCGGCGCTTTCCTCTGTTACCTCGTTTCATCCTCACAGCAGCATGGACGGTAGGTGGGGTCGCT
TCTACAATCATTTCTGATGATAGCTTGGGAATAGAGATAGGGGCAGTGACTTGCCTGATGTCGCACAGCCCTCTGGCTGTCCTGCTTTCC
CATATGGAGCAGTGGTGGTGTGGGCACCTGTGATGCAGGAGACTTTAAAAATGTCGTGAGGTCACGTGCTGCCCCTCCTGGTACGTGTGG
AATGCCCCTGGCCAGCAAGGGGTGCTTTTTTATCAGAGTTGGCAGCTGGCATGTGGGAACCGAGCAAGTGCTGCGTACCAAGTTACTTGT
TTTAAGGAGACCAAGTGCTCAGCGCCAGGTGGTTTTCTTTTTTGTCATAGTTACTTGCTATAACTCAGCTTGACTTCTGTCATGAATCAG
TGCTCTCTGGGAGGATGCAATACTCTGTTTGGGCATTAATTGGTAGCAGGTTGTCTCAACCAAAAAGACAGGAAACAGCAAAAGCCTCTC
TGAAATTAAGAGGAAAGTTACTCTCCCCACACCCATCAGAGTCTTTATTGGAGCCACCAGGTGAGCTGTGCAGCCTGGACAGGCCTGCAG
CTATAGGCCACCTTCCCAGTTTAGGTCCTCAGCACAGGGGAGCCCAAGTCACTGGGTGCCTTCCGAGGGCTGTCACTGGGCAGGCCATAT
ACAAGTCAGTGTGTGCGTGGGCACTGCAGTGTGTGCATGCCGTAGGTGTTGATGGGTGCTAGGAGGGGTGTCGTGTGCATGCGCGTTGAA
GAGGATCTGTATTGCCGTGACCTCTGTTCATGGATGAGTGCATTGTAATTTGTTCTCAGGCTGTGCTGTGAGGGCCGCCTTAACCCTTGC
TCCCTTCCCTTCTAGAGCTGCCTTAAGTTCTCCAGAACTTTTCTTCTGTAAAGGATATCTTGCCTGGAAGGGATATCTTGCCCTGTTTCT
CAAGGTTTTGTGAGAGTTTTGACTGGATGTGGCCCTGCATGACCCTCCTTCTCCTGTACTTCCTCTTTCCTTTCCAAATGGGAATTAGAA
CTGTGGGGCAGCAACAGTCTCAGAGCCAGTGAGAGGCCAGCTTAGAGAATGCTTCTGAGTTAGTGGGACTCTGTGTCACAAGTAAGCAAA
TGAATATATGAAAGAAATTATGGAGATAAGTTAGATTCTTGGTAATACTTAAATGTCTTGCTTTCTACTAACCTTTTGTTACTAAAGGTA
AAGGGTATAACTCAAACTTTTTGTGGACATTCTTTTCAAAATTTTTTAAGAACCCTGTACTATAAAAGGTTGAGTAAAAACAGGAAAGCG
TGCTATAAGTTCAAATCTGTTGTATTACCCTAAATTAGATAAACCAACCTGAATTATAGTAGATTTCTCAATAGATGAGGAACTGAAAAA
TACTATGTAAAATATCTTCCAAAATGCTTTTTATACTTTTTTTATTTGTAATTTGGTCTATCTAAAATGTTCGTTAGCTTAACTTAATGG
GCGTTATTGGATTCATATGACTAACGTTTCCTCAGTATTGTAATGCTTGAAATATTTGAAAGAAAAAATGTTGTTTTTTAGTTGAAACTG
GTATATATAATTCAGTGCTTGGCAGGTTAGTATATTTTTATGCATTTTTCAGAGTCAGCAGTTTCAAATCTTATTGTTATCATGTTATAA
AATTTTAGCCCACATTTCAGGCTCCGTAAATCATTTGAGCCATTATTTTTTCCCAACAAATGGTGAATTTTTTCTTTAAATGTGGATATA
TATGTTGTAATTTATGATTCCTGGTTATGTATTTTTGTGGGATCCTGCAGTAAAATTGACTTTTTTGTGTCTTTGGGAGATTTAAATTGC
GCTAACAGTGTTGCGCAAAAATGAGTTCATGCCATTTAACATATTGTATTTTAATTATTAACTGTATTAATTTACTATGAAATGGACATC
CTTTTAACTAAAATGGAATTGAACATTGCAGTTTTCAAATATTTTTCCTTGTTGGGTCTGGAAAAGGAATTCTACTTTGATCTGCATAGA
AAATTTTGATACAATTTTTTGAAAGTTCTTAGGTGAAACATTTACCCATTAAAAAGGAAGCAGAAATACTGAGACATGAAAGGCATTATC
AACTAACTCTAGACTCTAGAACCCATTCTAGCATATCTCACGTGCAATTTTTAAAAATAAGTTAATAATTCATCTCATATCAACAAAAGC
CTTTGAAACATGGGTTTTCACTAGATATCACCTAGTGCTAAGATAAAAACCAAAACAATATCAGAATTACATTTATGCTCTAAATTTGTA
GTTGTCCATTGTTGTGCTTAGTAAATGTGTGTCATTAATGCTGTATTCTCCTAGCTATTATGGAAACTTGTTTAAATAAAGATATGGATA
TAAAGAAAAAAACTGAAGGCACCTATGACTTACCTTACTGGGACCGGGCAGGTTGGTGGAAAGGAATGAAGCAGTTTCTTCCTGCAAAAG
CAGTGGACCATGAGGAAACCCCAGTTCGCTATAGCAGCAGCGAAGTTAATCACCTGAGTCCAAGAGAAGTCACCACAGTGCTGCAGGCTG
ACTCTGCAGAGTATGCTCAGCCACTGGTAGGAGGAATTGTTGGTACACTTCATCAAAGATCTACCTTTAAACCAGAAGAAGGAAAAGAAG
CAGGCTATGCAGACCTAGATCCTTACAACTCACCAGGGCAGGAAGTTTATCATGCCTATGCTGAACCACTCCCAATTACGGGGCCTGAGT
ATGCAACCCCAATCATCATGGACATGTCAGGGCACCCCACAACTTCAGTTGGTCAGCCCTCCACATCCACTTTCAAGGCTACGGGGAACC
AACCTCCCCCACTAGTGGGAACTTACAATACACTTCTCTCCAGGACTGACAGCTGCTCCTCAGCCCAGGCCCAGTATGATACCCCGAAAG
CTGGGAAGCCAGGTCTACCTGCCCCAGACGAATTGGTGTACCAGGTGCCACAGAGCACACAAGAAGTATCAGGAGCAGGAAGGGATGGGG
AATGTGATGTTTTTAAAGAAATCCTTTGAAGATGATGCTGCTTTTTACAAAGCATCGTTTTAAAGCACATGGCCTTTTTTTTTTAATTAT
TAGTGGTAGTAATATATAGAATGTATTACATAACTGTCACTGAAGTGGTTGGGGAAAATGTGGTGACTGAGGTACAGGAAACTACTAATC
TTGCCATCTTGCTTTAAGGTGTTATGGTGGCACAGTTACTGCTCGCCTGTTAAATTTCAAATGTCCTGTTTGATACTACTGTAGAACACT
ATTTTTAATACAGAAAAAGCTCCCTATAATGCACTTCAGAGAAATTAAAAATCACAGAGTATTTATTACCAATGCTGCAGGTACATTAAT
GAACTCGAGATGGCTCTGTAAGCCTGACTGGCAATAACGCACGGTACTGTTCTTGAAATACCTAATGGCTTGAAATTCTAGTCTGTTTGT
GAAAGATGGGTACTATCATGATTTCCTCTTCTATTCCTATATTCTTTTCTGGATTTTTTTTAATAATTAGTGATATAAGCATTGTTTTTA
TTGCAGCCATATCCACTTATCCATCTTAAGATCTGTAGCTGGGATTTTCTGACTTGTAATGAGCAGGGGGATTGCTTTTTCACTTTGTGA
CACTCTTTAGAGCTTTAATGCTTCACAGTATATGGCCTGGTCTCATCCTTGCGTGTTCCACTTGAGGCCCTTTGGTGTCTTGCCCCATTC
TTGTGTTTATAAAATGTTTGAGTATTTCTGATGAGTGATGCTTGCCTTAGTCTCATGAATTCAGATCCCTTCATGTCCTTTAAGTATGCT
CCTCAATGTGTAAACAGGAACAACTTTATGATTTGAAAGCTTTAAAGGAGATTCTTCTCCCACCCCCAACTTTATTTGCAATGGGATTTT
TCCTAGGAGAGTTATGAAAAGTTGAAGGCTTCTAAGGGAATACTGTAAACATGACCCACTTATATTTATCACAGTGAAAGGCAAAATTAT
TCACTCAGAAGTAATATAAATTACCTCTTTAAAAAGTAACCAGAATTTGTCCTTTTTGGTTTTATACATTCACAAACATATACATTTTTC
TTGAGTCTCAAGGTATTTTATATTTTTAGTCAGAAAAAATAATTTTTCATTTCAGTTTTCCATAAACTGTTACACAAAATATAAACCTAA
CGTGTATTTTTCAGGACTGCGTGATCGTGCACTTTGTGTGGTAAGAGGTTTGAGTAGTCCTATATGTCACCTAGGGAACAGACATTATAG
CTTACTAGCAAATGAATATTCATGCCTTGTTTTTGATACCTCCTGGCAGCTTCCATGTCACCACTTGTTCATACCTGCCCAGAGCTAGTT
TTAGACATGGCAAAATAGAAATCATCTGTAATTTATTAGCTAACAATGTAAAACCATCTTTTAAAGCCTTCAGACTGTCAAGACGACATG
AGCAGCTCACCATATGATAAAAATACATAAATTTGACATTCCCTCTTCCATAAACCTTTGTTTGTAGATTTAATGTTGAACAGTACTTTT
CCATAAAGTTCTAGTCACTTCTGTTGGCCTGAGCCACCAGATTATGATGTTGCCAGAATTCACTCAATTTGAATAAAGATGAACAGTATT
TGTTTTCTTGTTTCCATGAATTATATCAGTATTCTAAAACATCGCTTCAGAAAGAGAACTGTTTATTTCTGCAGGCTTCCTGTCCTTTTG
TGGTATGGTTTTTTGGCCTTATTTTCACTGGCTTTTCCTTCTCCAAACTTTGAGGCGTGATTTCATTCATTGAAGAATCAATACATATTT
TGTTTCAAAATGTTTGAAACAAAAGACATAGATGGTAGACTTTTATTAAAACATATATGGATGTGGAAAGCACATATATTAATGCAGTCA
TCCCTTTTCAGGTGGGAAGAGAGCAAACCAGTTGATTTTTTAATTCATCCTTAGTACACAGAGAATATACTTTTCCTCAAGTAATATACC
TGTTTGAAGCTTTAAGAGAGATGTTTTTGGTAACTATTTCATTTTCCCAAAGAAGTTTGCTATTCTTGTGTTAATTGTGTATACCTGATT
GTTTTTTCCTGGAGGTTTTTGTTGTTGTTGTTTAGTTTTGGGTTTTTTTTTTTTTAAGAGGGGCAAGTGTTTTCTGAAATGATGCATATT
TTAAGACTCGATTCATATTGCCACTGTGCTATCCTTGAACTACCAATAATTTTTATAAAATATCTAGTTTTTACTACTTTTATATAAACT
TTACTTTCCAGATGAAGAGCTGAGCCTGATTCAAATGGTTTTTCTGCTTTATACTTCTTTTTAGTTCATTGGTTTTTATAGTAGAGGTTT
TCTATTTTTTTTTTTTTTTTTTTTACTACATTTATATGTCTGATACATATACGGCTTTGGAGACAATCAAGTAACAACTGAAAATGTGAA
AGTAACCATATCTGACAAAATTCCCTTGAATTTTTATCCTTTGCTTGCAACATTTAAGACTCAAAGTCACTGGTATATTGGATTAAGTTT
TTTCCTGTTAATGCAATTATAGAAATACATCGGAGACACAACAAATGTGGCCATTACAGGTTTCATAAAATTACACTGACTTGGCTGTTA
CTTGATCTTAGGAAACAGCACAGTTTAAGATATTGTGAATTCTGACTTATACTTTATTAAATGCTGTAAATCTAAATAGATCCTGTTGGA
TGTGATGGGTCTAGTCCAGTTTATTTAAGTTCATGTTTCACTGTTTGCACTTTGCATTGAACAATGGGTTTATTCGCTGATGTAAACGGT
TCGAGTGAAGAATTAATGCAGTAAGTATGACAACACATACACACTTGCCTCTCCCCATCTCCAGAAGAGGGGAGCAGAGTCCGAGCTTAT
CTAAATATGAATGTGGCCACAAAGCTGTGGAAGGTGACAAAGCTTAAACACCTTTGCCCTGGCTCTGCATTGTCACCTAGAGAGCAAGAG
GTCTATAGAAACATCATGTCACATGAAACGATTCTCTGCTTTTTGGTTCTGAACTTGAAGTCCCTAAACTGCAAAATCTAAGAGTTGGGT
GGTTATTAAAATGCTTTTAAAGTCAACTGTGGCACCAATTCTAATGTAATCCAACTTGTGACTGTTTTTTTTTGTTTTGTTTTGTTTTTG
TGTGTGTGTGTGTGGCACTGGGAAAAGTGGAAACAAACATGTATTGAAATACATATTGGAAATAAAAATGGTTTGAGCGTCAGTGATATT
CTCCCAGAATGTACTTATCTTACCTCGGCATGTACTGTAGTCACTCAGTATTTGTATATGTTGCTAGAATTTAGATTGTAAAATAGTGAA
ATTTTAATGTGTTCATTTGTTTTTAATGTATATATGTCTTGCTCAGATTATTTGGTTTAAATAAAACAACCTTGAGGTTTGTAGCTTTTC

>56706_56706_1_MYO5A-DCBLD2_MYO5A_chr15_52599483_ENST00000356338_DCBLD2_chr3_98520493_ENST00000326840_length(amino acids)=1828AA_BP=
MAASELYTKFARVWIPDPEEVWKSAELLKDYKPGDKVLLLHLEEGKDLEYHLDPKTKELPHLRNPDILVGENDLTALSYLHEPAVLHNLR
VRFIDSKLIYTYCGIVLVAINPYEQLPIYGEDIINAYSGQNMGDMDPHIFAVAEEAYKQMARDERNQSIIVSGESGAGKTVSAKYAMRYF
ATVSGSASEANVEEKVLASNPIMESIGNAKTTRNDNSSRFGKYIEIGFDKRYRIIGANMRTYLLEKSRVVFQAEEERNYHIFYQLCASAK
LPEFKMLRLGNADNFNYTKQGGSPVIEGVDDAKEMAHTRQACTLLGISESHQMGIFRILAGILHLGNVGFTSRDADSCTIPPKHEPLCIF
CELMGVDYEEMCHWLCHRKLATATETYIKPISKLQATNARDALAKHIYAKLFNWIVDNVNQALHSAVKQHSFIGVLDIYGFETFEINSFE
QFCINYANEKLQQQFNMHVFKLEQEEYMKEQIPWTLIDFYDNQPCINLIESKLGILDLLDEECKMPKGTDDTWAQKLYNTHLNKCALFEK
PRLSNKAFIIQHFADKVEYQCEGFLEKNKDTVFEEQIKVLKSSKFKMLPELFQDDEKAISPTSATSSGRTPLTRTPAKPTKGRPGQMAKE
HKKTVGHQFRNSLHLLMETLNATTPHYVRCIKPNDFKFPFTFDEKRAVQQLRACGVLETIRISAAGFPSRWTYQEFFSRYRVLMKQKDVL
SDRKQTCKNVLEKLILDKDKYQFGKTKIFFRAGQVAYLEKLRADKLRAACIRIQKTIRGWLLRKKYLRMRKAAITMQRYVRGYQARCYAK
FLRRTKAATIIQKYWRMYVVRRRYKIRRAATIVLQSYLRGFLARNRYRKILREHKAVIIQKRVRGWLARTHYKRSMHAIIYLQCCFRRMM
AKRELKKLKIEARSVERYKKLHIGMENKIMQLQRKVDEQNKDYKCLVEKLTNLEGIYNSETEKLRSDLERLQLSEEEAKVATGRVLSLQE
EIAKLRKDLEQTRSEKKCIEEHADRYKQETEQLVSNLKEENTLLKQEKEALNHRIVQQAKEMTETMEKKLVEETKQLELDLNDERLRYQN
LLNEFSRLEERYDDLKEEMTLMVHVPKPGHKRTDSTHSSNESEYIFSSEIAEMEDIPSRTEEPSEKKVPLDMSLFLKLQKRVTELEQEKQ
VMQDELDRKEEQVLRSKAKEEERPQIRGAELEYESLKRQELESENKKLKNELNELRKALSEKSAPEVTAPGAPAYRVLMEQLTSVSEELD
VRKEEVLILRSQLVSQKEAIQPKDDKNTMTDSTILLEDVQKMKDKGEIAQAYIGLKETNRLLESQLQSQKRSHENEAEALRGEIQSLKEE
NNRQQQLLAQNLQLPPEARIEASLQHEITRLTNENLDLMEQLEKQDKTVRKLKKQLKVFAKKIGELEVGQMENISPGQIIDEPIRPVNIP
RKEKDFQGMLEYKKEDEQKLVKNLILELKPRGVAVNLIPGLPAYILFMCVRHADYLNDDQKVRSLLTSTINSIKKVLKKRGDDFETVSFW
LSNTCRFLHCLKQYSGEEGFMKHNTSRQNEHCLTNFDLAEYRQVLSDLAIQIYQQLVRVLENILQPMIVSGMLEHETIQGVSGVKPTGLR
KRTSSIADEGTYTLDSILRQLNSFHSVMCQHGMDPELIKQVVKQMFYIIGAITLNNLLLRKDMCSWSKGMQIRYNVSQLEEWLRDKNLMN
SGAKETLEPLIQAAQLLQVKKKTDDDAEAICSMCNALTTAQIVKVLNLYTPVNEFEERVSVSFIRTIQMRLRDRKDSPQLLMDAKHIFPV

--------------------------------------------------------------
>56706_56706_2_MYO5A-DCBLD2_MYO5A_chr15_52599483_ENST00000356338_DCBLD2_chr3_98520493_ENST00000326857_length(transcript)=14260nt_BP=11971nt
AGTCCGCTCGGGCGGCCGCCCAGGCGAGGTGCGGCCTCCGCACAGGCGGGGGGCGTAGGCGCGCGGGGCCCGCCATGGCTGCGTCGGAGC
TCTACACAAAGTTTGCCAGGGTTTGGATACCTGATCCAGAGGAAGTCTGGAAGTCAGCAGAGCTGCTCAAAGATTATAAGCCAGGAGATA
AAGTCCTCCTGCTTCACCTCGAGGAAGGAAAGGATTTGGAATACCATCTAGATCCAAAGACCAAGGAGCTGCCTCACTTACGAAATCCTG
ACATACTTGTTGGTGAAAATGACCTCACAGCCCTCAGCTATCTTCATGAGCCTGCTGTGCTCCATAATCTCAGAGTCCGCTTTATTGATT
CCAAACTTATTTATACGTATTGTGGTATAGTCCTAGTAGCTATAAATCCCTATGAACAGCTGCCTATTTATGGAGAAGATATTATTAATG
CATACAGTGGTCAGAACATGGGTGATATGGATCCACATATCTTTGCAGTAGCTGAAGAAGCTTACAAGCAAATGGCCAGAGATGAACGAA
ATCAGTCCATCATCGTAAGTGGAGAGTCTGGGGCAGGAAAAACAGTCTCAGCTAAGTATGCCATGCGATACTTTGCAACTGTGAGTGGTT
CTGCCAGTGAGGCCAATGTGGAGGAAAAGGTCTTGGCCTCCAACCCCATCATGGAGTCCATTGGAAATGCTAAAACAACCAGGAATGATA
ATAGCAGCCGTTTTGGGAAGTATATTGAGATTGGTTTTGATAAGAGATATCGAATCATTGGTGCCAATATGAGAACTTATCTTTTAGAGA
AATCCAGAGTGGTATTCCAGGCAGAAGAGGAGAGAAACTATCATATCTTCTATCAGCTTTGTGCCTCAGCAAAGTTACCTGAATTTAAAA
TGCTACGATTAGGAAATGCAGATAACTTTAATTACACAAAACAAGGAGGCAGTCCTGTGATTGAAGGAGTGGATGATGCAAAGGAGATGG
CACATACTAGGCAGGCCTGCACTTTGCTAGGAATTAGTGAATCTCATCAAATGGGAATTTTCCGAATACTTGCTGGCATCCTTCACTTAG
GCAATGTTGGATTTACATCCCGAGATGCAGACAGCTGCACAATACCTCCCAAGCATGAACCTCTCTGCATCTTCTGTGAACTCATGGGTG
TGGACTATGAGGAGATGTGTCACTGGCTCTGCCATCGGAAACTGGCTACTGCCACAGAGACATACATCAAGCCCATCTCCAAGCTGCAGG
CCACAAATGCCCGCGATGCTTTGGCCAAGCACATCTATGCCAAGCTCTTTAACTGGATTGTAGATAATGTCAATCAGGCTCTCCATTCTG
CTGTCAAACAGCACTCTTTTATTGGTGTGCTAGACATTTACGGATTTGAAACATTTGAGATAAATAGTTTTGAACAGTTTTGCATAAATT
ATGCAAATGAAAAACTACAGCAACAATTCAATATGCATGTCTTCAAATTGGAGCAAGAAGAATATATGAAGGAACAAATTCCATGGACAC
TCATAGATTTTTATGATAATCAGCCTTGTATTAATCTTATAGAATCAAAACTAGGCATTCTAGATTTACTGGATGAGGAATGCAAGATGC
CTAAAGGCACAGATGACACCTGGGCCCAAAAATTGTACAACACACATTTGAACAAATGTGCACTCTTTGAAAAGCCTCGTCTATCAAACA
AAGCTTTCATCATCCAACATTTTGCTGACAAAGTGGAATACCAGTGTGAAGGATTTCTCGAAAAGAATAAAGACACCGTTTTTGAAGAAC
AAATTAAAGTTCTTAAATCAAGCAAGTTTAAGATGCTACCAGAACTATTTCAAGATGATGAGAAGGCCATCAGTCCAACTTCAGCCACCT
CCTCAGGGCGCACACCCCTCACACGAACTCCTGCAAAGCCCACCAAAGGCAGACCAGGCCAAATGGCCAAAGAGCACAAGAAAACAGTGG
GGCATCAGTTCAGAAACTCCCTGCACCTGCTTATGGAGACACTCAATGCCACTACCCCTCACTATGTGCGCTGTATCAAGCCTAATGACT
TCAAGTTCCCATTCACGTTTGATGAGAAGAGGGCAGTGCAGCAGCTGAGAGCATGTGGTGTCCTGGAAACCATCCGAATCAGTGCGGCCG
GTTTCCCCTCACGGTGGACTTACCAAGAATTTTTCAGCCGCTACCGTGTCCTAATGAAGCAGAAAGATGTGCTGAGTGACAGAAAGCAAA
CATGCAAGAATGTGTTAGAGAAACTGATACTGGACAAGGACAAATACCAGTTTGGTAAGACAAAGATCTTTTTCCGTGCCGGTCAAGTGG
CCTATCTAGAAAAATTGAGAGCTGACAAACTGAGAGCTGCCTGCATCCGGATCCAGAAGACCATCCGAGGGTGGCTGCTGAGAAAGAAGT
ACCTACGCATGCGGAAGGCAGCCATCACCATGCAGAGATACGTGCGGGGCTACCAGGCCCGATGCTATGCTAAGTTTCTGCGCAGAACCA
AGGCAGCAACCATCATTCAAAAGTACTGGCGCATGTATGTGGTCCGCAGGAGGTACAAGATTAGACGAGCTGCCACTATCGTTCTTCAGT
CTTACTTGCGAGGCTTCTTGGCCAGAAATAGGTATCGCAAGATACTCCGTGAGCACAAAGCAGTCATCATTCAGAAGCGAGTCCGGGGCT
GGCTGGCCCGCACACACTACAAGAGGAGCATGCATGCCATCATCTACCTTCAGTGCTGCTTCAGGCGGATGATGGCCAAGCGTGAGCTAA
AGAAGCTCAAAATCGAGGCTCGCTCAGTGGAGCGCTATAAGAAGCTGCACATCGGCATGGAGAACAAGATCATGCAGCTGCAGCGCAAAG
TTGATGAGCAGAACAAAGACTACAAATGCCTTGTGGAGAAACTAACCAATCTGGAAGGAATATACAACTCTGAGACTGAGAAACTACGAA
GTGACTTAGAACGTCTTCAACTAAGTGAAGAGGAAGCGAAAGTTGCCACTGGGCGGGTCCTTAGTCTGCAGGAAGAAATTGCCAAGCTCC
GGAAAGACCTGGAGCAAACTCGTTCAGAGAAAAAATGCATTGAGGAACATGCAGATCGATACAAACAAGAAACAGAGCAGCTGGTATCAA
ATCTGAAGGAAGAAAATACTTTGCTGAAGCAAGAAAAAGAAGCCCTCAATCACCGCATCGTGCAGCAGGCTAAGGAGATGACAGAAACTA
TGGAGAAGAAGTTAGTAGAAGAAACGAAACAACTGGAACTCGACCTTAATGATGAAAGGCTGAGATATCAGAACCTTCTGAATGAGTTCA
GTCGCCTGGAAGAAAGATATGATGACCTCAAGGAAGAGATGACCCTTATGGTGCATGTGCCTAAGCCTGGACACAAGAGAACAGACTCCA
CCCACAGCAGCAACGAGTCTGAATATATCTTTAGCTCTGAAATTGCAGAAATGGAAGACATTCCATCAAGGACAGAGGAACCAAGTGAGA
AGAAGGTACCTCTGGACATGTCATTGTTCCTTAAGCTCCAGAAGCGGGTCACAGAGCTGGAGCAGGAGAAGCAGGTGATGCAGGATGAGC
TGGACCGCAAGGAGGAGCAGGTGCTCCGCAGCAAGGCCAAGGAAGAAGAAAGACCACAAATTAGAGGTGCAGAACTGGAATATGAGTCAC
TCAAGCGTCAAGAACTAGAATCAGAAAACAAAAAACTGAAGAATGAGCTAAATGAGTTGCGCAAGGCCCTCAGTGAGAAAAGTGCCCCAG
AGGTGACCGCCCCAGGTGCACCTGCCTACCGTGTCCTCATGGAGCAGCTGACCTCTGTGAGCGAGGAGCTTGATGTCCGCAAGGAGGAAG
TCCTCATCTTAAGGTCTCAACTGGTGAGCCAGAAAGAGGCCATCCAACCCAAGGATGACAAGAATACAATGACAGATTCCACAATACTTT
TGGAAGATGTACAAAAAATGAAAGATAAAGGTGAAATAGCACAAGCATACATTGGTTTGAAAGAAACAAATAGGCTCCTGGAATCCCAGC
TGCAGTCACAGAAGAGGAGCCATGAGAATGAGGCCGAGGCCCTCCGTGGGGAGATCCAGAGCCTGAAGGAGGAGAACAACCGACAGCAGC
AGCTGCTGGCCCAGAACCTGCAGCTGCCCCCAGAGGCCCGCATTGAGGCCAGCCTGCAGCACGAGATCACCCGGCTGACCAACGAAAACT
TGGATTTGATGGAACAACTTGAAAAACAGGATAAGACGGTCCGTAAACTGAAAAAACAACTGAAAGTATTTGCCAAAAAAATTGGCGAAC
TAGAAGTGGGCCAGATGGAGAACATATCCCCAGGACAGATCATTGATGAACCCATCCGACCAGTCAACATTCCCAGGAAAGAAAAGGATT
TCCAAGGGATGCTGGAATACAAGAAGGAGGATGAGCAAAAACTTGTTAAGAACCTGATTCTGGAACTGAAGCCACGTGGTGTAGCAGTCA
ATTTGATTCCAGGATTACCGGCATATATCCTGTTCATGTGTGTTCGACATGCTGACTACCTGAATGATGATCAGAAAGTAAGGTCGTTGC
TAACATCAACAATTAACAGCATCAAAAAAGTATTGAAGAAAAGAGGTGATGATTTTGAAACCGTCTCCTTCTGGCTCTCTAACACATGCC
GATTTTTGCACTGCTTGAAACAGTACAGTGGAGAAGAGGGCTTTATGAAGCACAACACATCTCGCCAGAATGAACACTGCCTCACCAATT
TTGACCTGGCTGAGTATCGGCAGGTGCTGAGTGACTTGGCCATTCAGATCTACCAGCAGCTCGTGCGGGTGTTAGAGAACATCCTTCAGC
CAATGATTGTCTCAGGCATGCTGGAACATGAAACGATTCAGGGCGTGTCTGGGGTGAAGCCCACAGGGTTGAGAAAGCGAACCTCCAGTA
TCGCCGATGAGGGCACCTACACACTGGACTCCATCCTCCGGCAGCTCAACTCCTTCCACTCGGTCATGTGTCAGCATGGCATGGACCCTG
AACTGATCAAGCAGGTGGTCAAGCAGATGTTCTACATCATAGGGGCCATCACCCTGAACAACCTTCTCCTGCGGAAGGACATGTGCTCCT
GGAGTAAAGGCATGCAGATCAGGTACAATGTCAGTCAACTGGAAGAATGGCTGCGTGACAAGAATCTGATGAATAGTGGGGCTAAAGAAA
CCCTGGAACCTCTCATTCAGGCTGCTCAACTTTTGCAAGTGAAAAAGAAAACAGATGATGATGCAGAAGCCATTTGTTCTATGTGCAATG
CTTTAACTACTGCCCAGATTGTGAAAGTGTTGAATTTGTATACTCCAGTTAATGAGTTTGAAGAAAGAGTCTCTGTGTCGTTCATTCGTA
CTATACAGATGCGTTTACGAGACAGGAAAGACTCTCCCCAGCTGCTCATGGATGCTAAACACATCTTTCCTGTCACCTTTCCTTTCAACC
CATCTTCCCTCGCACTAGAAACCATCCAGATTCCAGCCAGCCTCGGCCTGGGCTTCATTTCACGGGTCTGAAAGTGATGTCCAGGCAAAA
ATTGACAATACATTTCTTGCCCGAAATAAGAACCCATTATTTCCAGTGAGTTACTGAAAATACATTTTTAAAGAGAAAGTACTGATTATC
TCCCAAATGAGAAGTCATTAACTGGAAATCTCCCTAGAATACTTTCATCACTTTGGAAACAAAGATAGGCTCTTTCGTGCTGTGTTATCT
TTATAGCAACACTCATCCTTAACCAACTAGGTACCGTGAGTTTACATACAGGAGAATGATGGAAGGAAGGGAGGAAGGAAAGGAGGAGAA
AAATGTGTCTTCAGCTGGCAGCATTTATTTTAAATCCTTAGCACTGAGTTTGAATGGTATAAAAAGTATAACTTCCATAGATGAGCTGTT
GTTAGGAAGGCACCAAAGAACCTCCTCTGCACTAAACAGGAGAATGGAAAGAAAAGTCTCCATTGAGTACATATCATGTCAGTTTAGTAA
TCAATTATGTTGATATTGTTAAACTGGTTCAAAGAAATAAACTGGCAATATGTAAAGTAATTCCTCATTTGTGTCACTATGATATAGAGA
TATTAAAGGAATGTTGGTTTGCTAAATAGTATAGATGTCCATTTGTACTATAGTTTACTGAGCATTTTAAATTGCTGCTACATACTGTCT
TCTTAAAATGTAAGTGATATTAGGCACTACAATAAGTTTCTCTTGTCAATTCTGTTTACAATTCAATCAGATCACAGTTTTAACTGGATT
ATATGCAAATACCTACAGATTCACCTGCACAAGTAGCAGACACTGGAAAGTCATGTAGTAATATGACAAAATGCTTGACATTTAGGGGTA
GGATTAGACAAAGTGGCTATTGTTGATGTCATTATTTATTCAGGATGTATTACATTGATGTGCTCATTAATTTTCCCTGGGTGGATATTG
CGTCAGGGTACAGTGTTCTGTGAAGTGACTTATTTTTAACTACCAGATCTGATTCCTTCAGTGCATATTTTCAACCTTGACAGGTTTTCT
CTCTTCTTAATTTATTAAGAATTAATCTCGGCTGGGCGCGGTGGCTCACGCCTGTAATCCCAGCACTTTGGGAAGCCAAGGTGGGCGGAT
CACTTCAGGTTAGGAGTTGGAGACCAGCCTGGCCAACATGGCGAAACCCTGTCTCTACTAAAAATACAAAAATTAGCCGGGCGTGGTGGC
ACTTGCCTGTAATCCCAGCTACTCGGGAGGCTGAGGCACGAGAATCGATTAAACCTGGGAGGCGGAGATTGCAATGAGATCGAACCACTG
CACTCCAGCCTGGGTGACAGAGAGAGACACTGCCTTGGAAAAAAAAAGAATCTCACTCACTATCTAGAGAGGATTGTCAGAATATTCACG
ATTCAGGTCTTGAAACTTTGATTATGCAAAAGAAGGTATATAATAAATATTTCATTATGATTCAGTTTTTAAGGCTTTGCAGCTTCTATA
AGTGTTCTCAGATGCCACTAGATAATTTTAAAAGCATCATATTAGAAATACTTTAAGAAGACTTATATAAGAAATAGAAGATTGTTGAAT
TTTACAGAGGATTTGGTTCATTAAGACCCAGATTCTGTAAGTTTTCATTCTGAAATTCTAGTTAAACATATTCACCATTTTTCTTAGGAA
TCTTATACAATAAATCCTTCAGGTTGCACAAAAGCAAATTATTAGTTTTCATTAGAAACTCTGGTTCTGAATTACAATCATAGGTTATAT
AAATTTAACTGTTAGATGGTCTATAAATCTTATTAAAATATGTGCAATATTTATGGAAGTCAAACAGCTTCATATCAGTGATAAAGATTG
TTATTAAAAGATAAATACTGTCTGTTAATTTACATGGGCCTCAAGTTCCTCGTTTATAAAATAAGAGAGTTGGACACTGATTCTTAACAT
CTCCTCCACATTTAAAATTCTCTCTTCTCAGCCCTTAGATTCTAGAGAGAAAAAGCTGCAGTTACTCAGTAAGTCCATTCTCTGATGGAA
AGACCAGTGTGTAGTGCCTGTCAATTCCTTAGGATTAATCAAATGTAAAATCACAAGTTTGTGTAGCTGTAACCTTTCTTAAATGTACAT
GATTTATGTACATGCTTTTAGAAGGTCCTACTATATTTGTATTATAATTAGTTTAAGTAATTTTTATTACATCATGTATTGCTTTATTCA
GTTTGAATACATTTATTTATTTATTTGCAGTATCAACCAGAAACACTACCAATTGCATCAAATTCTCCCAGTTTTTCCTGGTTGTCAATG
CGGTTTTCAATGCACAATTAAGTCATAGCCATTTGGTTCGTACCAAATGTGTCAGAATCTAACAGCATCCGATAGGCTGTAAGTTGGGGA
GTTGCTAAGAAAATGCAACGTGGTACAGGCTGTCCGCCTCAGCCCTGGAAATCTCCCAGACCTCCCCCAGCTTCATCCTGTGTAGCACGA
CTCAACGTGCACCCTGAATCTTCTCAGGTCTTCCAGGTCATGCTGTAGCTGTCACTGCCATGCAGCCCTTTTTTTTACTCCGGACAGCTC
ATGTACTGAAGCGTCATGAAAGAAAGGCTGTGGTCTGAGCCCTTCTCTCCCATCTCCTGTCTTTGTCCTGTCAAGTGCTGGAGCCAGAGC
TCCTACAGCTGCCCTTGGTGGTTTCTCCTGTTCAGCGATGGTGGCACAAAGGTTCTGCTATTCCAGGGCTCCAGCTTCCTCCCAGGTCTA
CCCAGAGCTCCAGATGGGGGTCTGAATTAACCTCTCTTGGTGGCCTGGAGATTTTTAGTCATTGACAAGAATACCTTGTAACCAGGGAAC
CCCAAGGCCCAGTAAATGATTCTGTATACCATTTTCTTGAAGGTACAAGAAGATTCTGCCGACTATGGGGATCTTTGGGCCAGTTTGAGG
ATTGCTTTCCCTCTGAGGTTCTTTCTCTCTGTCAGCCACACTTTCTCACCCAACTTCAGACACACCCTGCCAGCCTTTCCCCTACTCATT
CACTCTTCCCCTTCCCTCAACTTAATCGTCTATCCCGTTGCCTGCTGTTTGACTGTGCACTGAAGGCAGGTGGATGGAGTCAGTCCTCAG
TTGCCCCTGCTGGCCTTCCTGGTGCTTACCATCAGCCCAATCTTTGCACAGTCCTTGTTGTTCTTACTTCTCTGCATGCATTCCTTCAGA
AGATCAGTCATCAACTTTTTCTTAATTCCTCTGTGACACACAATGGGAATTCAAAGGAAGAGATCTTAAAAGTCACAACAGTTCTTTATC
TTAATAATCCCCTCCCCATTCACCTTACTACATGCAGACTCACCTCACACCCTTACAACTTGAAGCTGAAAATTTAAAAGTAATTTCCCT
TTTTGCAGCTTTTCCTCAGGTTAAGGCTTTGATCTGCCTGAGAGTAACTCTAAAAGGAGGGAAGATAAATATGGGATAAAATCCACAAAG
TGTAGCTTCTAATTCCTTTGGAAGTTTAAAAAATTTCCACATATCTGATGCTTCTTTTGTCAGGTGCAGAAGCACAAAAACATATTCCGA
AGCCAACTGATAGGGAATTTGGGGATTATTGTCAGTTTGGAGAATTTGCTGTGTTATTTCTTCATTTCCATGGATAGCTCATAGTTGGCT
CTTTCTGGGTGAGTAATTATGTGTAATATAGATCAAATCTTTTACTAAGGTTACAGCTACATGTTAGGGGAGGCTATGAAAATACTATAT
TATTATAATTTCAGTGCAGTGATTGTTGTGAGAAATAACTTTCATGGTAACCCTAGGAAAATGGGCACCTGCCACCATCCTGAGAAGTCC
TCACACAATGCCCTTTCTCTCTTACACACACACACACACACATACACACACACACACCCCCGTCACTAATTCATAGAGTTCCTTAGCAGG
CATAGTCAAGGATCCTCTGGGTAATGTCAGCTGCTTAGTGATAAAACAGAGCCAAAACTAGTGCATCCTGTTGAAAGTAATGCAGAAACA
GTACCTGGGTCCAGATATGCTTTCCTGCGGCGCTTTCCTCTGTTACCTCGTTTCATCCTCACAGCAGCATGGACGGTAGGTGGGGTCGCT
TCTACAATCATTTCTGATGATAGCTTGGGAATAGAGATAGGGGCAGTGACTTGCCTGATGTCGCACAGCCCTCTGGCTGTCCTGCTTTCC
CATATGGAGCAGTGGTGGTGTGGGCACCTGTGATGCAGGAGACTTTAAAAATGTCGTGAGGTCACGTGCTGCCCCTCCTGGTACGTGTGG
AATGCCCCTGGCCAGCAAGGGGTGCTTTTTTATCAGAGTTGGCAGCTGGCATGTGGGAACCGAGCAAGTGCTGCGTACCAAGTTACTTGT
TTTAAGGAGACCAAGTGCTCAGCGCCAGGTGGTTTTCTTTTTTGTCATAGTTACTTGCTATAACTCAGCTTGACTTCTGTCATGAATCAG
TGCTCTCTGGGAGGATGCAATACTCTGTTTGGGCATTAATTGGTAGCAGGTTGTCTCAACCAAAAAGACAGGAAACAGCAAAAGCCTCTC
TGAAATTAAGAGGAAAGTTACTCTCCCCACACCCATCAGAGTCTTTATTGGAGCCACCAGGTGAGCTGTGCAGCCTGGACAGGCCTGCAG
CTATAGGCCACCTTCCCAGTTTAGGTCCTCAGCACAGGGGAGCCCAAGTCACTGGGTGCCTTCCGAGGGCTGTCACTGGGCAGGCCATAT
ACAAGTCAGTGTGTGCGTGGGCACTGCAGTGTGTGCATGCCGTAGGTGTTGATGGGTGCTAGGAGGGGTGTCGTGTGCATGCGCGTTGAA
GAGGATCTGTATTGCCGTGACCTCTGTTCATGGATGAGTGCATTGTAATTTGTTCTCAGGCTGTGCTGTGAGGGCCGCCTTAACCCTTGC
TCCCTTCCCTTCTAGAGCTGCCTTAAGTTCTCCAGAACTTTTCTTCTGTAAAGGATATCTTGCCTGGAAGGGATATCTTGCCCTGTTTCT
CAAGGTTTTGTGAGAGTTTTGACTGGATGTGGCCCTGCATGACCCTCCTTCTCCTGTACTTCCTCTTTCCTTTCCAAATGGGAATTAGAA
CTGTGGGGCAGCAACAGTCTCAGAGCCAGTGAGAGGCCAGCTTAGAGAATGCTTCTGAGTTAGTGGGACTCTGTGTCACAAGTAAGCAAA
TGAATATATGAAAGAAATTATGGAGATAAGTTAGATTCTTGGTAATACTTAAATGTCTTGCTTTCTACTAACCTTTTGTTACTAAAGGTA
AAGGGTATAACTCAAACTTTTTGTGGACATTCTTTTCAAAATTTTTTAAGAACCCTGTACTATAAAAGGTTGAGTAAAAACAGGAAAGCG
TGCTATAAGTTCAAATCTGTTGTATTACCCTAAATTAGATAAACCAACCTGAATTATAGTAGATTTCTCAATAGATGAGGAACTGAAAAA
TACTATGTAAAATATCTTCCAAAATGCTTTTTATACTTTTTTTATTTGTAATTTGGTCTATCTAAAATGTTCGTTAGCTTAACTTAATGG
GCGTTATTGGATTCATATGACTAACGTTTCCTCAGTATTGTAATGCTTGAAATATTTGAAAGAAAAAATGTTGTTTTTTAGTTGAAACTG
GTATATATAATTCAGTGCTTGGCAGGTTAGTATATTTTTATGCATTTTTCAGAGTCAGCAGTTTCAAATCTTATTGTTATCATGTTATAA
AATTTTAGCCCACATTTCAGGCTCCGTAAATCATTTGAGCCATTATTTTTTCCCAACAAATGGTGAATTTTTTCTTTAAATGTGGATATA
TATGTTGTAATTTATGATTCCTGGTTATGTATTTTTGTGGGATCCTGCAGTAAAATTGACTTTTTTGTGTCTTTGGGAGATTTAAATTGC
GCTAACAGTGTTGCGCAAAAATGAGTTCATGCCATTTAACATATTGTATTTTAATTATTAACTGTATTAATTTACTATGAAATGGACATC
CTTTTAACTAAAATGGAATTGAACATTGCAGTTTTCAAATATTTTTCCTTGTTGGGTCTGGAAAAGGAATTCTACTTTGATCTGCATAGA
AAATTTTGATACAATTTTTTGAAAGTTCTTAGGTGAAACATTTACCCATTAAAAAGGAAGCAGAAATACTGAGACATGAAAGGCATTATC
AACTAACTCTAGACTCTAGAACCCATTCTAGCATATCTCACGTGCAATTTTTAAAAATAAGTTAATAATTCATCTCATATCAACAAAAGC
CTTTGAAACATGGGTTTTCACTAGATATCACCTAGTGCTAAGATAAAAACCAAAACAATATCAGAATTACATTTATGCTCTAAATTTGTA
GTTGTCCATTGTTGTGCTTAGTAAATGTGTGTCATTAATGCTGTATTCTCCTAGCTATTATGGAAACTTGTTTAAATAAAGATATGGATA
TAAAGAAAAAAACTGAAGGCACCTATGACTTACCTTACTGGGACCGGGCAGGTTTTTATTTAATGGTCTCTTTGGCTTGCCGTCACAATG
AAGGTTGGTGGAAAGGAATGAAGCAGTTTCTTCCTGCAAAAGCAGTGGACCATGAGGAAACCCCAGTTCGCTATAGCAGCAGCGAAGTTA
ATCACCTGAGTCCAAGAGAAGTCACCACAGTGCTGCAGGCTGACTCTGCAGAGTATGCTCAGCCACTGGTAGGAGGAATTGTTGGTACAC
TTCATCAAAGATCTACCTTTAAACCAGAAGAAGGAAAAGAAGCAGGCTATGCAGACCTAGATCCTTACAACTCACCAGGGCAGGAAGTTT
ATCATGCCTATGCTGAACCACTCCCAATTACGGGGCCTGAGTATGCAACCCCAATCATCATGGACATGTCAGGGCACCCCACAACTTCAG
TTGGTCAGCCCTCCACATCCACTTTCAAGGCTACGGGGAACCAACCTCCCCCACTAGTGGGAACTTACAATACACTTCTCTCCAGGACTG
ACAGCTGCTCCTCAGCCCAGGCCCAGTATGATACCCCGAAAGCTGGGAAGCCAGGTCTACCTGCCCCAGACGAATTGGTGTACCAGGTGC
CACAGAGCACACAAGAAGTATCAGGAGCAGGAAGGGATGGGGAATGTGATGTTTTTAAAGAAATCCTTTGAAGATGATGCTGCTTTTTAC
AAAGCATCGTTTTAAAGCACATGGCCTTTTTTTTTTAATTATTAGTGGTAGTAATATATAGAATGTATTACATAACTGTCACTGAAGTGG
TTGGGGAAAATGTGGTGACTGAGGTACAGGAAACTACTAATCTTGCCATCTTGCTTTAAGGTGTTATGGTGGCACAGTTACTGCTCGCCT
GTTAAATTTCAAATGTCCTGTTTGATACTACTGTAGAACACTATTTTTAATACAGAAAAAGCTCCCTATAATGCACTTCAGAGAAATTAA
AAATCACAGAGTATTTATTACCAATGCTGCAGGTACATTAATGAACTCGAGATGGCTCTGTAAGCCTGACTGGCAATAACGCACGGTACT
GTTCTTGAAATACCTAATGGCTTGAAATTCTAGTCTGTTTGTGAAAGATGGGTACTATCATGATTTCCTCTTCTATTCCTATATTCTTTT
CTGGATTTTTTTTAATAATTAGTGATATAAGCATTGTTTTTATTGCAGCCATATCCACTTATCCATCTTAAGATCTGTAGCTGGGATTTT
CTGACTTGTAATGAGCAGGGGGATTGCTTTTTCACTTTGTGACACTCTTTAGAGCTTTAATGCTTCACAGTATATGGCCTGGTCTCATCC
TTGCGTGTTCCACTTGAGGCCCTTTGGTGTCTTGCCCCATTCTTGTGTTTATAAAATGTTTGAGTATTTCTGATGAGTGATGCTTGCCTT
AGTCTCATGAATTCAGATCCCTTCATGTCCTTTAAGTATGCTCCTCAATGTGTAAACAGGAACAACTTTATGATTTGAAAGCTTTAAAGG
AGATTCTTCTCCCACCCCCAACTTTATTTGCAATGGGATTTTTCCTAGGAGAGTTATGAAAAGTTGAAGGCTTCTAAGGGAATACTGTAA
ACATGACCCACTTATATTTATCACAGTGAAAGGCAAAATTATTCACTCAGAAGTAATATAAATTACCTCTTTAAAAAGTAACCAGAATTT
GTCCTTTTTGGTTTTATACATTCACAAACATATACATTTTTCTTGAGTCTCAAGGTATTTTATATTTTTAGTCAGAAAAAATAATTTTTC
ATTTCAGTTTTCCATAAACTGTTACACAAAATATAAACCTAACGTGTATTTTTCAGGACTGCGTGATCGTGCACTTTGTGTGGTAAGAGG
TTTGAGTAGTCCTATATGTCACCTAGGGAACAGACATTATAGCTTACTAGCAAATGAATATTCATGCCTTGTTTTTGATACCTCCTGGCA
GCTTCCATGTCACCACTTGTTCATACCTGCCCAGAGCTAGTTTTAGACATGGCAAAATAGAAATCATCTGTAATTTATTAGCTAACAATG
TAAAACCATCTTTTAAAGCCTTCAGACTGTCAAGACGACATGAGCAGCTCACCATATGATAAAAATACATAAATTTGACATTCCCTCTTC
CATAAACCTTTGTTTGTAGATTTAATGTTGAACAGTACTTTTCCATAAAGTTCTAGTCACTTCTGTTGGCCTGAGCCACCAGATTATGAT

>56706_56706_2_MYO5A-DCBLD2_MYO5A_chr15_52599483_ENST00000356338_DCBLD2_chr3_98520493_ENST00000326857_length(amino acids)=1828AA_BP=
MAASELYTKFARVWIPDPEEVWKSAELLKDYKPGDKVLLLHLEEGKDLEYHLDPKTKELPHLRNPDILVGENDLTALSYLHEPAVLHNLR
VRFIDSKLIYTYCGIVLVAINPYEQLPIYGEDIINAYSGQNMGDMDPHIFAVAEEAYKQMARDERNQSIIVSGESGAGKTVSAKYAMRYF
ATVSGSASEANVEEKVLASNPIMESIGNAKTTRNDNSSRFGKYIEIGFDKRYRIIGANMRTYLLEKSRVVFQAEEERNYHIFYQLCASAK
LPEFKMLRLGNADNFNYTKQGGSPVIEGVDDAKEMAHTRQACTLLGISESHQMGIFRILAGILHLGNVGFTSRDADSCTIPPKHEPLCIF
CELMGVDYEEMCHWLCHRKLATATETYIKPISKLQATNARDALAKHIYAKLFNWIVDNVNQALHSAVKQHSFIGVLDIYGFETFEINSFE
QFCINYANEKLQQQFNMHVFKLEQEEYMKEQIPWTLIDFYDNQPCINLIESKLGILDLLDEECKMPKGTDDTWAQKLYNTHLNKCALFEK
PRLSNKAFIIQHFADKVEYQCEGFLEKNKDTVFEEQIKVLKSSKFKMLPELFQDDEKAISPTSATSSGRTPLTRTPAKPTKGRPGQMAKE
HKKTVGHQFRNSLHLLMETLNATTPHYVRCIKPNDFKFPFTFDEKRAVQQLRACGVLETIRISAAGFPSRWTYQEFFSRYRVLMKQKDVL
SDRKQTCKNVLEKLILDKDKYQFGKTKIFFRAGQVAYLEKLRADKLRAACIRIQKTIRGWLLRKKYLRMRKAAITMQRYVRGYQARCYAK
FLRRTKAATIIQKYWRMYVVRRRYKIRRAATIVLQSYLRGFLARNRYRKILREHKAVIIQKRVRGWLARTHYKRSMHAIIYLQCCFRRMM
AKRELKKLKIEARSVERYKKLHIGMENKIMQLQRKVDEQNKDYKCLVEKLTNLEGIYNSETEKLRSDLERLQLSEEEAKVATGRVLSLQE
EIAKLRKDLEQTRSEKKCIEEHADRYKQETEQLVSNLKEENTLLKQEKEALNHRIVQQAKEMTETMEKKLVEETKQLELDLNDERLRYQN
LLNEFSRLEERYDDLKEEMTLMVHVPKPGHKRTDSTHSSNESEYIFSSEIAEMEDIPSRTEEPSEKKVPLDMSLFLKLQKRVTELEQEKQ
VMQDELDRKEEQVLRSKAKEEERPQIRGAELEYESLKRQELESENKKLKNELNELRKALSEKSAPEVTAPGAPAYRVLMEQLTSVSEELD
VRKEEVLILRSQLVSQKEAIQPKDDKNTMTDSTILLEDVQKMKDKGEIAQAYIGLKETNRLLESQLQSQKRSHENEAEALRGEIQSLKEE
NNRQQQLLAQNLQLPPEARIEASLQHEITRLTNENLDLMEQLEKQDKTVRKLKKQLKVFAKKIGELEVGQMENISPGQIIDEPIRPVNIP
RKEKDFQGMLEYKKEDEQKLVKNLILELKPRGVAVNLIPGLPAYILFMCVRHADYLNDDQKVRSLLTSTINSIKKVLKKRGDDFETVSFW
LSNTCRFLHCLKQYSGEEGFMKHNTSRQNEHCLTNFDLAEYRQVLSDLAIQIYQQLVRVLENILQPMIVSGMLEHETIQGVSGVKPTGLR
KRTSSIADEGTYTLDSILRQLNSFHSVMCQHGMDPELIKQVVKQMFYIIGAITLNNLLLRKDMCSWSKGMQIRYNVSQLEEWLRDKNLMN
SGAKETLEPLIQAAQLLQVKKKTDDDAEAICSMCNALTTAQIVKVLNLYTPVNEFEERVSVSFIRTIQMRLRDRKDSPQLLMDAKHIFPV

--------------------------------------------------------------
>56706_56706_3_MYO5A-DCBLD2_MYO5A_chr15_52599483_ENST00000399231_DCBLD2_chr3_98520493_ENST00000326840_length(transcript)=16314nt_BP=12225nt
ACCCCGGGCAGGTGGAGCGCTCGCGGCTGCTCGCGGCGAGCCCGGGAGTGATGGCGAGGCCCCTGCGGGCGGCCAGCGCCTGAGGCGCCC
CGCCCCGCCCCGCCCCGCGCGGCCCTCCCCGCCCGGCCCTGCCCTGCCCTGCTCCCTGCCGGCGGCTGCGGGCGCTTCCTAGTCCGCTCG
GGCGGCCGCCCAGGCGAGGTGCGGCCTCCGCACAGGCGGGGGGCGTAGGCGCGCGGGGCCCGCCATGGCTGCGTCGGAGCTCTACACAAA
GTTTGCCAGGGTTTGGATACCTGATCCAGAGGAAGTCTGGAAGTCAGCAGAGCTGCTCAAAGATTATAAGCCAGGAGATAAAGTCCTCCT
GCTTCACCTCGAGGAAGGAAAGGATTTGGAATACCATCTAGATCCAAAGACCAAGGAGCTGCCTCACTTACGAAATCCTGACATACTTGT
TGGTGAAAATGACCTCACAGCCCTCAGCTATCTTCATGAGCCTGCTGTGCTCCATAATCTCAGAGTCCGCTTTATTGATTCCAAACTTAT
TTATACGTATTGTGGTATAGTCCTAGTAGCTATAAATCCCTATGAACAGCTGCCTATTTATGGAGAAGATATTATTAATGCATACAGTGG
TCAGAACATGGGTGATATGGATCCACATATCTTTGCAGTAGCTGAAGAAGCTTACAAGCAAATGGCCAGAGATGAACGAAATCAGTCCAT
CATCGTAAGTGGAGAGTCTGGGGCAGGAAAAACAGTCTCAGCTAAGTATGCCATGCGATACTTTGCAACTGTGAGTGGTTCTGCCAGTGA
GGCCAATGTGGAGGAAAAGGTCTTGGCCTCCAACCCCATCATGGAGTCCATTGGAAATGCTAAAACAACCAGGAATGATAATAGCAGCCG
TTTTGGGAAGTATATTGAGATTGGTTTTGATAAGAGATATCGAATCATTGGTGCCAATATGAGAACTTATCTTTTAGAGAAATCCAGAGT
GGTATTCCAGGCAGAAGAGGAGAGAAACTATCATATCTTCTATCAGCTTTGTGCCTCAGCAAAGTTACCTGAATTTAAAATGCTACGATT
AGGAAATGCAGATAACTTTAATTACACAAAACAAGGAGGCAGTCCTGTGATTGAAGGAGTGGATGATGCAAAGGAGATGGCACATACTAG
GCAGGCCTGCACTTTGCTAGGAATTAGTGAATCTCATCAAATGGGAATTTTCCGAATACTTGCTGGCATCCTTCACTTAGGCAATGTTGG
ATTTACATCCCGAGATGCAGACAGCTGCACAATACCTCCCAAGCATGAACCTCTCTGCATCTTCTGTGAACTCATGGGTGTGGACTATGA
GGAGATGTGTCACTGGCTCTGCCATCGGAAACTGGCTACTGCCACAGAGACATACATCAAGCCCATCTCCAAGCTGCAGGCCACAAATGC
CCGCGATGCTTTGGCCAAGCACATCTATGCCAAGCTCTTTAACTGGATTGTAGATAATGTCAATCAGGCTCTCCATTCTGCTGTCAAACA
GCACTCTTTTATTGGTGTGCTAGACATTTACGGATTTGAAACATTTGAGATAAATAGTTTTGAACAGTTTTGCATAAATTATGCAAATGA
AAAACTACAGCAACAATTCAATATGCATGTCTTCAAATTGGAGCAAGAAGAATATATGAAGGAACAAATTCCATGGACACTCATAGATTT
TTATGATAATCAGCCTTGTATTAATCTTATAGAATCAAAACTAGGCATTCTAGATTTACTGGATGAGGAATGCAAGATGCCTAAAGGCAC
AGATGACACCTGGGCCCAAAAATTGTACAACACACATTTGAACAAATGTGCACTCTTTGAAAAGCCTCGTCTATCAAACAAAGCTTTCAT
CATCCAACATTTTGCTGACAAAGTGGAATACCAGTGTGAAGGATTTCTCGAAAAGAATAAAGACACCGTTTTTGAAGAACAAATTAAAGT
TCTTAAATCAAGCAAGTTTAAGATGCTACCAGAACTATTTCAAGATGATGAGAAGGCCATCAGTCCAACTTCAGCCACCTCCTCAGGGCG
CACACCCCTCACACGAACTCCTGCAAAGCCCACCAAAGGCAGACCAGGCCAAATGGCCAAAGAGCACAAGAAAACAGTGGGGCATCAGTT
CAGAAACTCCCTGCACCTGCTTATGGAGACACTCAATGCCACTACCCCTCACTATGTGCGCTGTATCAAGCCTAATGACTTCAAGTTCCC
ATTCACGTTTGATGAGAAGAGGGCAGTGCAGCAGCTGAGAGCATGTGGTGTCCTGGAAACCATCCGAATCAGTGCGGCCGGTTTCCCCTC
ACGGTGGACTTACCAAGAATTTTTCAGCCGCTACCGTGTCCTAATGAAGCAGAAAGATGTGCTGAGTGACAGAAAGCAAACATGCAAGAA
TGTGTTAGAGAAACTGATACTGGACAAGGACAAATACCAGTTTGGTAAGACAAAGATCTTTTTCCGTGCCGGTCAAGTGGCCTATCTAGA
AAAATTGAGAGCTGACAAACTGAGAGCTGCCTGCATCCGGATCCAGAAGACCATCCGAGGGTGGCTGCTGAGAAAGAAGTACCTACGCAT
GCGGAAGGCAGCCATCACCATGCAGAGATACGTGCGGGGCTACCAGGCCCGATGCTATGCTAAGTTTCTGCGCAGAACCAAGGCAGCAAC
CATCATTCAAAAGTACTGGCGCATGTATGTGGTCCGCAGGAGGTACAAGATTAGACGAGCTGCCACTATCGTTCTTCAGTCTTACTTGCG
AGGCTTCTTGGCCAGAAATAGGTATCGCAAGATACTCCGTGAGCACAAAGCAGTCATCATTCAGAAGCGAGTCCGGGGCTGGCTGGCCCG
CACACACTACAAGAGGAGCATGCATGCCATCATCTACCTTCAGTGCTGCTTCAGGCGGATGATGGCCAAGCGTGAGCTAAAGAAGCTCAA
AATCGAGGCTCGCTCAGTGGAGCGCTATAAGAAGCTGCACATCGGCATGGAGAACAAGATCATGCAGCTGCAGCGCAAAGTTGATGAGCA
GAACAAAGACTACAAATGCCTTGTGGAGAAACTAACCAATCTGGAAGGAATATACAACTCTGAGACTGAGAAACTACGAAGTGACTTAGA
ACGTCTTCAACTAAGTGAAGAGGAAGCGAAAGTTGCCACTGGGCGGGTCCTTAGTCTGCAGGAAGAAATTGCCAAGCTCCGGAAAGACCT
GGAGCAAACTCGTTCAGAGAAAAAATGCATTGAGGAACATGCAGATCGATACAAACAAGAAACAGAGCAGCTGGTATCAAATCTGAAGGA
AGAAAATACTTTGCTGAAGCAAGAAAAAGAAGCCCTCAATCACCGCATCGTGCAGCAGGCTAAGGAGATGACAGAAACTATGGAGAAGAA
GTTAGTAGAAGAAACGAAACAACTGGAACTCGACCTTAATGATGAAAGGCTGAGATATCAGAACCTTCTGAATGAGTTCAGTCGCCTGGA
AGAAAGATATGATGACCTCAAGGAAGAGATGACCCTTATGGTGCATGTGCCTAAGCCTGGACACAAGAGAACAGACTCCACCCACAGCAG
CAACGAGTCTGAATATATCTTTAGCTCTGAAATTGCAGAAATGGAAGACATTCCATCAAGGACAGAGGAACCAAGTGAGAAGAAGGTACC
TCTGGACATGTCATTGTTCCTTAAGCTCCAGAAGCGGGTCACAGAGCTGGAGCAGGAGAAGCAGGTGATGCAGGATGAGCTGGACCGCAA
GGAGGAGCAGGTGCTCCGCAGCAAGGCCAAGGAAGAAGAAAGACCACAAATTAGAGGTGCAGAACTGGAATATGAGTCACTCAAGCGTCA
AGAACTAGAATCAGAAAACAAAAAACTGAAGAATGAGCTAAATGAGTTGCGCAAGGCCCTCAGTGAGAAAAGTGCCCCAGAGGTGACCGC
CCCAGGTGCACCTGCCTACCGTGTCCTCATGGAGCAGCTGACCTCTGTGAGCGAGGAGCTTGATGTCCGCAAGGAGGAAGTCCTCATCTT
AAGGTCTCAACTGGTGAGCCAGAAAGAGGCCATCCAACCCAAGGATGACAAGAATACAATGACAGATTCCACAATACTTTTGGAAGATGT
ACAAAAAATGAAAGATAAAGGTGAAATAGCACAAGCATACATTGGTTTGAAAGAAACAAATAGATCATCTGCTCTGGATTACCATGAGTT
GAATGAGGATGGAGAGCTGTGGCTGGTTTATGAAGGGTTAAAACAAGCCAACAGGCTCCTGGAATCCCAGCTGCAGTCACAGAAGAGGAG
CCATGAGAATGAGGCCGAGGCCCTCCGTGGGGAGATCCAGAGCCTGAAGGAGGAGAACAACCGACAGCAGCAGCTGCTGGCCCAGAACCT
GCAGCTGCCCCCAGAGGCCCGCATTGAGGCCAGCCTGCAGCACGAGATCACCCGGCTGACCAACGAAAACTTGGATTTGATGGAACAACT
TGAAAAACAGGATAAGACGGTCCGTAAACTGAAAAAACAACTGAAAGTATTTGCCAAAAAAATTGGCGAACTAGAAGTGGGCCAGATGGA
GAACATATCCCCAGGACAGATCATTGATGAACCCATCCGACCAGTCAACATTCCCAGGAAAGAAAAGGATTTCCAAGGGATGCTGGAATA
CAAGAAGGAGGATGAGCAAAAACTTGTTAAGAACCTGATTCTGGAACTGAAGCCACGTGGTGTAGCAGTCAATTTGATTCCAGGATTACC
GGCATATATCCTGTTCATGTGTGTTCGACATGCTGACTACCTGAATGATGATCAGAAAGTAAGGTCGTTGCTAACATCAACAATTAACAG
CATCAAAAAAGTATTGAAGAAAAGAGGTGATGATTTTGAAACCGTCTCCTTCTGGCTCTCTAACACATGCCGATTTTTGCACTGCTTGAA
ACAGTACAGTGGAGAAGAGGGCTTTATGAAGCACAACACATCTCGCCAGAATGAACACTGCCTCACCAATTTTGACCTGGCTGAGTATCG
GCAGGTGCTGAGTGACTTGGCCATTCAGATCTACCAGCAGCTCGTGCGGGTGTTAGAGAACATCCTTCAGCCAATGATTGTCTCAGGCAT
GCTGGAACATGAAACGATTCAGGGCGTGTCTGGGGTGAAGCCCACAGGGTTGAGAAAGCGAACCTCCAGTATCGCCGATGAGGGCACCTA
CACACTGGACTCCATCCTCCGGCAGCTCAACTCCTTCCACTCGGTCATGTGTCAGCATGGCATGGACCCTGAACTGATCAAGCAGGTGGT
CAAGCAGATGTTCTACATCATAGGGGCCATCACCCTGAACAACCTTCTCCTGCGGAAGGACATGTGCTCCTGGAGTAAAGGCATGCAGAT
CAGGTACAATGTCAGTCAACTGGAAGAATGGCTGCGTGACAAGAATCTGATGAATAGTGGGGCTAAAGAAACCCTGGAACCTCTCATTCA
GGCTGCTCAACTTTTGCAAGTGAAAAAGAAAACAGATGATGATGCAGAAGCCATTTGTTCTATGTGCAATGCTTTAACTACTGCCCAGAT
TGTGAAAGTGTTGAATTTGTATACTCCAGTTAATGAGTTTGAAGAAAGAGTCTCTGTGTCGTTCATTCGTACTATACAGATGCGTTTACG
AGACAGGAAAGACTCTCCCCAGCTGCTCATGGATGCTAAACACATCTTTCCTGTCACCTTTCCTTTCAACCCATCTTCCCTCGCACTAGA
AACCATCCAGATTCCAGCCAGCCTCGGCCTGGGCTTCATTTCACGGGTCTGAAAGTGATGTCCAGGCAAAAATTGACAATACATTTCTTG
CCCGAAATAAGAACCCATTATTTCCAGTGAGTTACTGAAAATACATTTTTAAAGAGAAAGTACTGATTATCTCCCAAATGAGAAGTCATT
AACTGGAAATCTCCCTAGAATACTTTCATCACTTTGGAAACAAAGATAGGCTCTTTCGTGCTGTGTTATCTTTATAGCAACACTCATCCT
TAACCAACTAGGTACCGTGAGTTTACATACAGGAGAATGATGGAAGGAAGGGAGGAAGGAAAGGAGGAGAAAAATGTGTCTTCAGCTGGC
AGCATTTATTTTAAATCCTTAGCACTGAGTTTGAATGGTATAAAAAGTATAACTTCCATAGATGAGCTGTTGTTAGGAAGGCACCAAAGA
ACCTCCTCTGCACTAAACAGGAGAATGGAAAGAAAAGTCTCCATTGAGTACATATCATGTCAGTTTAGTAATCAATTATGTTGATATTGT
TAAACTGGTTCAAAGAAATAAACTGGCAATATGTAAAGTAATTCCTCATTTGTGTCACTATGATATAGAGATATTAAAGGAATGTTGGTT
TGCTAAATAGTATAGATGTCCATTTGTACTATAGTTTACTGAGCATTTTAAATTGCTGCTACATACTGTCTTCTTAAAATGTAAGTGATA
TTAGGCACTACAATAAGTTTCTCTTGTCAATTCTGTTTACAATTCAATCAGATCACAGTTTTAACTGGATTATATGCAAATACCTACAGA
TTCACCTGCACAAGTAGCAGACACTGGAAAGTCATGTAGTAATATGACAAAATGCTTGACATTTAGGGGTAGGATTAGACAAAGTGGCTA
TTGTTGATGTCATTATTTATTCAGGATGTATTACATTGATGTGCTCATTAATTTTCCCTGGGTGGATATTGCGTCAGGGTACAGTGTTCT
GTGAAGTGACTTATTTTTAACTACCAGATCTGATTCCTTCAGTGCATATTTTCAACCTTGACAGGTTTTCTCTCTTCTTAATTTATTAAG
AATTAATCTCGGCTGGGCGCGGTGGCTCACGCCTGTAATCCCAGCACTTTGGGAAGCCAAGGTGGGCGGATCACTTCAGGTTAGGAGTTG
GAGACCAGCCTGGCCAACATGGCGAAACCCTGTCTCTACTAAAAATACAAAAATTAGCCGGGCGTGGTGGCACTTGCCTGTAATCCCAGC
TACTCGGGAGGCTGAGGCACGAGAATCGATTAAACCTGGGAGGCGGAGATTGCAATGAGATCGAACCACTGCACTCCAGCCTGGGTGACA
GAGAGAGACACTGCCTTGGAAAAAAAAAGAATCTCACTCACTATCTAGAGAGGATTGTCAGAATATTCACGATTCAGGTCTTGAAACTTT
GATTATGCAAAAGAAGGTATATAATAAATATTTCATTATGATTCAGTTTTTAAGGCTTTGCAGCTTCTATAAGTGTTCTCAGATGCCACT
AGATAATTTTAAAAGCATCATATTAGAAATACTTTAAGAAGACTTATATAAGAAATAGAAGATTGTTGAATTTTACAGAGGATTTGGTTC
ATTAAGACCCAGATTCTGTAAGTTTTCATTCTGAAATTCTAGTTAAACATATTCACCATTTTTCTTAGGAATCTTATACAATAAATCCTT
CAGGTTGCACAAAAGCAAATTATTAGTTTTCATTAGAAACTCTGGTTCTGAATTACAATCATAGGTTATATAAATTTAACTGTTAGATGG
TCTATAAATCTTATTAAAATATGTGCAATATTTATGGAAGTCAAACAGCTTCATATCAGTGATAAAGATTGTTATTAAAAGATAAATACT
GTCTGTTAATTTACATGGGCCTCAAGTTCCTCGTTTATAAAATAAGAGAGTTGGACACTGATTCTTAACATCTCCTCCACATTTAAAATT
CTCTCTTCTCAGCCCTTAGATTCTAGAGAGAAAAAGCTGCAGTTACTCAGTAAGTCCATTCTCTGATGGAAAGACCAGTGTGTAGTGCCT
GTCAATTCCTTAGGATTAATCAAATGTAAAATCACAAGTTTGTGTAGCTGTAACCTTTCTTAAATGTACATGATTTATGTACATGCTTTT
AGAAGGTCCTACTATATTTGTATTATAATTAGTTTAAGTAATTTTTATTACATCATGTATTGCTTTATTCAGTTTGAATACATTTATTTA
TTTATTTGCAGTATCAACCAGAAACACTACCAATTGCATCAAATTCTCCCAGTTTTTCCTGGTTGTCAATGCGGTTTTCAATGCACAATT
AAGTCATAGCCATTTGGTTCGTACCAAATGTGTCAGAATCTAACAGCATCCGATAGGCTGTAAGTTGGGGAGTTGCTAAGAAAATGCAAC
GTGGTACAGGCTGTCCGCCTCAGCCCTGGAAATCTCCCAGACCTCCCCCAGCTTCATCCTGTGTAGCACGACTCAACGTGCACCCTGAAT
CTTCTCAGGTCTTCCAGGTCATGCTGTAGCTGTCACTGCCATGCAGCCCTTTTTTTTACTCCGGACAGCTCATGTACTGAAGCGTCATGA
AAGAAAGGCTGTGGTCTGAGCCCTTCTCTCCCATCTCCTGTCTTTGTCCTGTCAAGTGCTGGAGCCAGAGCTCCTACAGCTGCCCTTGGT
GGTTTCTCCTGTTCAGCGATGGTGGCACAAAGGTTCTGCTATTCCAGGGCTCCAGCTTCCTCCCAGGTCTACCCAGAGCTCCAGATGGGG
GTCTGAATTAACCTCTCTTGGTGGCCTGGAGATTTTTAGTCATTGACAAGAATACCTTGTAACCAGGGAACCCCAAGGCCCAGTAAATGA
TTCTGTATACCATTTTCTTGAAGGTACAAGAAGATTCTGCCGACTATGGGGATCTTTGGGCCAGTTTGAGGATTGCTTTCCCTCTGAGGT
TCTTTCTCTCTGTCAGCCACACTTTCTCACCCAACTTCAGACACACCCTGCCAGCCTTTCCCCTACTCATTCACTCTTCCCCTTCCCTCA
ACTTAATCGTCTATCCCGTTGCCTGCTGTTTGACTGTGCACTGAAGGCAGGTGGATGGAGTCAGTCCTCAGTTGCCCCTGCTGGCCTTCC
TGGTGCTTACCATCAGCCCAATCTTTGCACAGTCCTTGTTGTTCTTACTTCTCTGCATGCATTCCTTCAGAAGATCAGTCATCAACTTTT
TCTTAATTCCTCTGTGACACACAATGGGAATTCAAAGGAAGAGATCTTAAAAGTCACAACAGTTCTTTATCTTAATAATCCCCTCCCCAT
TCACCTTACTACATGCAGACTCACCTCACACCCTTACAACTTGAAGCTGAAAATTTAAAAGTAATTTCCCTTTTTGCAGCTTTTCCTCAG
GTTAAGGCTTTGATCTGCCTGAGAGTAACTCTAAAAGGAGGGAAGATAAATATGGGATAAAATCCACAAAGTGTAGCTTCTAATTCCTTT
GGAAGTTTAAAAAATTTCCACATATCTGATGCTTCTTTTGTCAGGTGCAGAAGCACAAAAACATATTCCGAAGCCAACTGATAGGGAATT
TGGGGATTATTGTCAGTTTGGAGAATTTGCTGTGTTATTTCTTCATTTCCATGGATAGCTCATAGTTGGCTCTTTCTGGGTGAGTAATTA
TGTGTAATATAGATCAAATCTTTTACTAAGGTTACAGCTACATGTTAGGGGAGGCTATGAAAATACTATATTATTATAATTTCAGTGCAG
TGATTGTTGTGAGAAATAACTTTCATGGTAACCCTAGGAAAATGGGCACCTGCCACCATCCTGAGAAGTCCTCACACAATGCCCTTTCTC
TCTTACACACACACACACACACATACACACACACACACCCCCGTCACTAATTCATAGAGTTCCTTAGCAGGCATAGTCAAGGATCCTCTG
GGTAATGTCAGCTGCTTAGTGATAAAACAGAGCCAAAACTAGTGCATCCTGTTGAAAGTAATGCAGAAACAGTACCTGGGTCCAGATATG
CTTTCCTGCGGCGCTTTCCTCTGTTACCTCGTTTCATCCTCACAGCAGCATGGACGGTAGGTGGGGTCGCTTCTACAATCATTTCTGATG
ATAGCTTGGGAATAGAGATAGGGGCAGTGACTTGCCTGATGTCGCACAGCCCTCTGGCTGTCCTGCTTTCCCATATGGAGCAGTGGTGGT
GTGGGCACCTGTGATGCAGGAGACTTTAAAAATGTCGTGAGGTCACGTGCTGCCCCTCCTGGTACGTGTGGAATGCCCCTGGCCAGCAAG
GGGTGCTTTTTTATCAGAGTTGGCAGCTGGCATGTGGGAACCGAGCAAGTGCTGCGTACCAAGTTACTTGTTTTAAGGAGACCAAGTGCT
CAGCGCCAGGTGGTTTTCTTTTTTGTCATAGTTACTTGCTATAACTCAGCTTGACTTCTGTCATGAATCAGTGCTCTCTGGGAGGATGCA
ATACTCTGTTTGGGCATTAATTGGTAGCAGGTTGTCTCAACCAAAAAGACAGGAAACAGCAAAAGCCTCTCTGAAATTAAGAGGAAAGTT
ACTCTCCCCACACCCATCAGAGTCTTTATTGGAGCCACCAGGTGAGCTGTGCAGCCTGGACAGGCCTGCAGCTATAGGCCACCTTCCCAG
TTTAGGTCCTCAGCACAGGGGAGCCCAAGTCACTGGGTGCCTTCCGAGGGCTGTCACTGGGCAGGCCATATACAAGTCAGTGTGTGCGTG
GGCACTGCAGTGTGTGCATGCCGTAGGTGTTGATGGGTGCTAGGAGGGGTGTCGTGTGCATGCGCGTTGAAGAGGATCTGTATTGCCGTG
ACCTCTGTTCATGGATGAGTGCATTGTAATTTGTTCTCAGGCTGTGCTGTGAGGGCCGCCTTAACCCTTGCTCCCTTCCCTTCTAGAGCT
GCCTTAAGTTCTCCAGAACTTTTCTTCTGTAAAGGATATCTTGCCTGGAAGGGATATCTTGCCCTGTTTCTCAAGGTTTTGTGAGAGTTT
TGACTGGATGTGGCCCTGCATGACCCTCCTTCTCCTGTACTTCCTCTTTCCTTTCCAAATGGGAATTAGAACTGTGGGGCAGCAACAGTC
TCAGAGCCAGTGAGAGGCCAGCTTAGAGAATGCTTCTGAGTTAGTGGGACTCTGTGTCACAAGTAAGCAAATGAATATATGAAAGAAATT
ATGGAGATAAGTTAGATTCTTGGTAATACTTAAATGTCTTGCTTTCTACTAACCTTTTGTTACTAAAGGTAAAGGGTATAACTCAAACTT
TTTGTGGACATTCTTTTCAAAATTTTTTAAGAACCCTGTACTATAAAAGGTTGAGTAAAAACAGGAAAGCGTGCTATAAGTTCAAATCTG
TTGTATTACCCTAAATTAGATAAACCAACCTGAATTATAGTAGATTTCTCAATAGATGAGGAACTGAAAAATACTATGTAAAATATCTTC
CAAAATGCTTTTTATACTTTTTTTATTTGTAATTTGGTCTATCTAAAATGTTCGTTAGCTTAACTTAATGGGCGTTATTGGATTCATATG
ACTAACGTTTCCTCAGTATTGTAATGCTTGAAATATTTGAAAGAAAAAATGTTGTTTTTTAGTTGAAACTGGTATATATAATTCAGTGCT
TGGCAGGTTAGTATATTTTTATGCATTTTTCAGAGTCAGCAGTTTCAAATCTTATTGTTATCATGTTATAAAATTTTAGCCCACATTTCA
GGCTCCGTAAATCATTTGAGCCATTATTTTTTCCCAACAAATGGTGAATTTTTTCTTTAAATGTGGATATATATGTTGTAATTTATGATT
CCTGGTTATGTATTTTTGTGGGATCCTGCAGTAAAATTGACTTTTTTGTGTCTTTGGGAGATTTAAATTGCGCTAACAGTGTTGCGCAAA
AATGAGTTCATGCCATTTAACATATTGTATTTTAATTATTAACTGTATTAATTTACTATGAAATGGACATCCTTTTAACTAAAATGGAAT
TGAACATTGCAGTTTTCAAATATTTTTCCTTGTTGGGTCTGGAAAAGGAATTCTACTTTGATCTGCATAGAAAATTTTGATACAATTTTT
TGAAAGTTCTTAGGTGAAACATTTACCCATTAAAAAGGAAGCAGAAATACTGAGACATGAAAGGCATTATCAACTAACTCTAGACTCTAG
AACCCATTCTAGCATATCTCACGTGCAATTTTTAAAAATAAGTTAATAATTCATCTCATATCAACAAAAGCCTTTGAAACATGGGTTTTC
ACTAGATATCACCTAGTGCTAAGATAAAAACCAAAACAATATCAGAATTACATTTATGCTCTAAATTTGTAGTTGTCCATTGTTGTGCTT
AGTAAATGTGTGTCATTAATGCTGTATTCTCCTAGCTATTATGGAAACTTGTTTAAATAAAGATATGGATATAAAAAAGAAAAAAACTGA
AGGCACCTATGACTTACCTTACTGGGACCGGGCAGGTTGGTGGAAAGGAATGAAGCAGTTTCTTCCTGCAAAAGCAGTGGACCATGAGGA
AACCCCAGTTCGCTATAGCAGCAGCGAAGTTAATCACCTGAGTCCAAGAGAAGTCACCACAGTGCTGCAGGCTGACTCTGCAGAGTATGC
TCAGCCACTGGTAGGAGGAATTGTTGGTACACTTCATCAAAGATCTACCTTTAAACCAGAAGAAGGAAAAGAAGCAGGCTATGCAGACCT
AGATCCTTACAACTCACCAGGGCAGGAAGTTTATCATGCCTATGCTGAACCACTCCCAATTACGGGGCCTGAGTATGCAACCCCAATCAT
CATGGACATGTCAGGGCACCCCACAACTTCAGTTGGTCAGCCCTCCACATCCACTTTCAAGGCTACGGGGAACCAACCTCCCCCACTAGT
GGGAACTTACAATACACTTCTCTCCAGGACTGACAGCTGCTCCTCAGCCCAGGCCCAGTATGATACCCCGAAAGCTGGGAAGCCAGGTCT
ACCTGCCCCAGACGAATTGGTGTACCAGGTGCCACAGAGCACACAAGAAGTATCAGGAGCAGGAAGGGATGGGGAATGTGATGTTTTTAA
AGAAATCCTTTGAAGATGATGCTGCTTTTTACAAAGCATCGTTTTAAAGCACATGGCCTTTTTTTTTTAATTATTAGTGGTAGTAATATA
TAGAATGTATTACATAACTGTCACTGAAGTGGTTGGGGAAAATGTGGTGACTGAGGTACAGGAAACTACTAATCTTGCCATCTTGCTTTA
AGGTGTTATGGTGGCACAGTTACTGCTCGCCTGTTAAATTTCAAATGTCCTGTTTGATACTACTGTAGAACACTATTTTTAATACAGAAA
AAGCTCCCTATAATGCACTTCAGAGAAATTAAAAATCACAGAGTATTTATTACCAATGCTGCAGGTACATTAATGAACTCGAGATGGCTC
TGTAAGCCTGACTGGCAATAACGCACGGTACTGTTCTTGAAATACCTAATGGCTTGAAATTCTAGTCTGTTTGTGAAAGATGGGTACTAT
CATGATTTCCTCTTCTATTCCTATATTCTTTTCTGGATTTTTTTTAATAATTAGTGATATAAGCATTGTTTTTATTGCAGCCATATCCAC
TTATCCATCTTAAGATCTGTAGCTGGGATTTTCTGACTTGTAATGAGCAGGGGGATTGCTTTTTCACTTTGTGACACTCTTTAGAGCTTT
AATGCTTCACAGTATATGGCCTGGTCTCATCCTTGCGTGTTCCACTTGAGGCCCTTTGGTGTCTTGCCCCATTCTTGTGTTTATAAAATG
TTTGAGTATTTCTGATGAGTGATGCTTGCCTTAGTCTCATGAATTCAGATCCCTTCATGTCCTTTAAGTATGCTCCTCAATGTGTAAACA
GGAACAACTTTATGATTTGAAAGCTTTAAAGGAGATTCTTCTCCCACCCCCAACTTTATTTGCAATGGGATTTTTCCTAGGAGAGTTATG
AAAAGTTGAAGGCTTCTAAGGGAATACTGTAAACATGACCCACTTATATTTATCACAGTGAAAGGCAAAATTATTCACTCAGAAGTAATA
TAAATTACCTCTTTAAAAAGTAACCAGAATTTGTCCTTTTTGGTTTTATACATTCACAAACATATACATTTTTCTTGAGTCTCAAGGTAT
TTTATATTTTTAGTCAGAAAAAATAATTTTTCATTTCAGTTTTCCATAAACTGTTACACAAAATATAAACCTAACGTGTATTTTTCAGGA
CTGCGTGATCGTGCACTTTGTGTGGTAAGAGGTTTGAGTAGTCCTATATGTCACCTAGGGAACAGACATTATAGCTTACTAGCAAATGAA
TATTCATGCCTTGTTTTTGATACCTCCTGGCAGCTTCCATGTCACCACTTGTTCATACCTGCCCAGAGCTAGTTTTAGACATGGCAAAAT
AGAAATCATCTGTAATTTATTAGCTAACAATGTAAAACCATCTTTTAAAGCCTTCAGACTGTCAAGACGACATGAGCAGCTCACCATATG
ATAAAAATACATAAATTTGACATTCCCTCTTCCATAAACCTTTGTTTGTAGATTTAATGTTGAACAGTACTTTTCCATAAAGTTCTAGTC
ACTTCTGTTGGCCTGAGCCACCAGATTATGATGTTGCCAGAATTCACTCAATTTGAATAAAGATGAACAGTATTTGTTTTCTTGTTTCCA
TGAATTATATCAGTATTCTAAAACATCGCTTCAGAAAGAGAACTGTTTATTTCTGCAGGCTTCCTGTCCTTTTGTGGTATGGTTTTTTGG
CCTTATTTTCACTGGCTTTTCCTTCTCCAAACTTTGAGGCGTGATTTCATTCATTGAAGAATCAATACATATTTTGTTTCAAAATGTTTG
AAACAAAAGACATAGATGGTAGACTTTTATTAAAACATATATGGATGTGGAAAGCACATATATTAATGCAGTCATCCCTTTTCAGGTGGG
AAGAGAGCAAACCAGTTGATTTTTTAATTCATCCTTAGTACACAGAGAATATACTTTTCCTCAAGTAATATACCTGTTTGAAGCTTTAAG
AGAGATGTTTTTGGTAACTATTTCATTTTCCCAAAGAAGTTTGCTATTCTTGTGTTAATTGTGTATACCTGATTGTTTTTTCCTGGAGGT
TTTTGTTGTTGTTGTTTAGTTTTGGGTTTTTTTTTTTTTAAGAGGGGCAAGTGTTTTCTGAAATGATGCATATTTTAAGACTCGATTCAT
ATTGCCACTGTGCTATCCTTGAACTACCAATAATTTTTATAAAATATCTAGTTTTTACTACTTTTATATAAACTTTACTTTCCAGATGAA
GAGCTGAGCCTGATTCAAATGGTTTTTCTGCTTTATACTTCTTTTTAGTTCATTGGTTTTTATAGTAGAGGTTTTCTATTTTTTTTTTTT
TTTTTTTTACTACATTTATATGTCTGATACATATACGGCTTTGGAGACAATCAAGTAACAACTGAAAATGTGAAAGTAACCATATCTGAC
AAAATTCCCTTGAATTTTTATCCTTTGCTTGCAACATTTAAGACTCAAAGTCACTGGTATATTGGATTAAGTTTTTTCCTGTTAATGCAA
TTATAGAAATACATCGGAGACACAACAAATGTGGCCATTACAGGTTTCATAAAATTACACTGACTTGGCTGTTACTTGATCTTAGGAAAC
AGCACAGTTTAAGATATTGTGAATTCTGACTTATACTTTATTAAATGCTGTAAATCTAAATAGATCCTGTTGGATGTGATGGGTCTAGTC
CAGTTTATTTAAGTTCATGTTTCACTGTTTGCACTTTGCATTGAACAATGGGTTTATTCGCTGATGTAAACGGTTCGAGTGAAGAATTAA
TGCAGTAAGTATGACAACACATACACACTTGCCTCTCCCCATCTCCAGAAGAGGGGAGCAGAGTCCGAGCTTATCTAAATATGAATGTGG
CCACAAAGCTGTGGAAGGTGACAAAGCTTAAACACCTTTGCCCTGGCTCTGCATTGTCACCTAGAGAGCAAGAGGTCTATAGAAACATCA
TGTCACATGAAACGATTCTCTGCTTTTTGGTTCTGAACTTGAAGTCCCTAAACTGCAAAATCTAAGAGTTGGGTGGTTATTAAAATGCTT
TTAAAGTCAACTGTGGCACCAATTCTAATGTAATCCAACTTGTGACTGTTTTTTTTTGTTTTGTTTTGTTTTTGTGTGTGTGTGTGTGGC
ACTGGGAAAAGTGGAAACAAACATGTATTGAAATACATATTGGAAATAAAAATGGTTTGAGCGTCAGTGATATTCTCCCAGAATGTACTT
ATCTTACCTCGGCATGTACTGTAGTCACTCAGTATTTGTATATGTTGCTAGAATTTAGATTGTAAAATAGTGAAATTTTAATGTGTTCAT
TTGTTTTTAATGTATATATGTCTTGCTCAGATTATTTGGTTTAAATAAAACAACCTTGAGGTTTGTAGCTTTTCCTTATACTATAAAATG

>56706_56706_3_MYO5A-DCBLD2_MYO5A_chr15_52599483_ENST00000399231_DCBLD2_chr3_98520493_ENST00000326840_length(amino acids)=1855AA_BP=
MAASELYTKFARVWIPDPEEVWKSAELLKDYKPGDKVLLLHLEEGKDLEYHLDPKTKELPHLRNPDILVGENDLTALSYLHEPAVLHNLR
VRFIDSKLIYTYCGIVLVAINPYEQLPIYGEDIINAYSGQNMGDMDPHIFAVAEEAYKQMARDERNQSIIVSGESGAGKTVSAKYAMRYF
ATVSGSASEANVEEKVLASNPIMESIGNAKTTRNDNSSRFGKYIEIGFDKRYRIIGANMRTYLLEKSRVVFQAEEERNYHIFYQLCASAK
LPEFKMLRLGNADNFNYTKQGGSPVIEGVDDAKEMAHTRQACTLLGISESHQMGIFRILAGILHLGNVGFTSRDADSCTIPPKHEPLCIF
CELMGVDYEEMCHWLCHRKLATATETYIKPISKLQATNARDALAKHIYAKLFNWIVDNVNQALHSAVKQHSFIGVLDIYGFETFEINSFE
QFCINYANEKLQQQFNMHVFKLEQEEYMKEQIPWTLIDFYDNQPCINLIESKLGILDLLDEECKMPKGTDDTWAQKLYNTHLNKCALFEK
PRLSNKAFIIQHFADKVEYQCEGFLEKNKDTVFEEQIKVLKSSKFKMLPELFQDDEKAISPTSATSSGRTPLTRTPAKPTKGRPGQMAKE
HKKTVGHQFRNSLHLLMETLNATTPHYVRCIKPNDFKFPFTFDEKRAVQQLRACGVLETIRISAAGFPSRWTYQEFFSRYRVLMKQKDVL
SDRKQTCKNVLEKLILDKDKYQFGKTKIFFRAGQVAYLEKLRADKLRAACIRIQKTIRGWLLRKKYLRMRKAAITMQRYVRGYQARCYAK
FLRRTKAATIIQKYWRMYVVRRRYKIRRAATIVLQSYLRGFLARNRYRKILREHKAVIIQKRVRGWLARTHYKRSMHAIIYLQCCFRRMM
AKRELKKLKIEARSVERYKKLHIGMENKIMQLQRKVDEQNKDYKCLVEKLTNLEGIYNSETEKLRSDLERLQLSEEEAKVATGRVLSLQE
EIAKLRKDLEQTRSEKKCIEEHADRYKQETEQLVSNLKEENTLLKQEKEALNHRIVQQAKEMTETMEKKLVEETKQLELDLNDERLRYQN
LLNEFSRLEERYDDLKEEMTLMVHVPKPGHKRTDSTHSSNESEYIFSSEIAEMEDIPSRTEEPSEKKVPLDMSLFLKLQKRVTELEQEKQ
VMQDELDRKEEQVLRSKAKEEERPQIRGAELEYESLKRQELESENKKLKNELNELRKALSEKSAPEVTAPGAPAYRVLMEQLTSVSEELD
VRKEEVLILRSQLVSQKEAIQPKDDKNTMTDSTILLEDVQKMKDKGEIAQAYIGLKETNRSSALDYHELNEDGELWLVYEGLKQANRLLE
SQLQSQKRSHENEAEALRGEIQSLKEENNRQQQLLAQNLQLPPEARIEASLQHEITRLTNENLDLMEQLEKQDKTVRKLKKQLKVFAKKI
GELEVGQMENISPGQIIDEPIRPVNIPRKEKDFQGMLEYKKEDEQKLVKNLILELKPRGVAVNLIPGLPAYILFMCVRHADYLNDDQKVR
SLLTSTINSIKKVLKKRGDDFETVSFWLSNTCRFLHCLKQYSGEEGFMKHNTSRQNEHCLTNFDLAEYRQVLSDLAIQIYQQLVRVLENI
LQPMIVSGMLEHETIQGVSGVKPTGLRKRTSSIADEGTYTLDSILRQLNSFHSVMCQHGMDPELIKQVVKQMFYIIGAITLNNLLLRKDM
CSWSKGMQIRYNVSQLEEWLRDKNLMNSGAKETLEPLIQAAQLLQVKKKTDDDAEAICSMCNALTTAQIVKVLNLYTPVNEFEERVSVSF

--------------------------------------------------------------
>56706_56706_4_MYO5A-DCBLD2_MYO5A_chr15_52599483_ENST00000399231_DCBLD2_chr3_98520493_ENST00000326857_length(transcript)=14514nt_BP=12225nt
ACCCCGGGCAGGTGGAGCGCTCGCGGCTGCTCGCGGCGAGCCCGGGAGTGATGGCGAGGCCCCTGCGGGCGGCCAGCGCCTGAGGCGCCC
CGCCCCGCCCCGCCCCGCGCGGCCCTCCCCGCCCGGCCCTGCCCTGCCCTGCTCCCTGCCGGCGGCTGCGGGCGCTTCCTAGTCCGCTCG
GGCGGCCGCCCAGGCGAGGTGCGGCCTCCGCACAGGCGGGGGGCGTAGGCGCGCGGGGCCCGCCATGGCTGCGTCGGAGCTCTACACAAA
GTTTGCCAGGGTTTGGATACCTGATCCAGAGGAAGTCTGGAAGTCAGCAGAGCTGCTCAAAGATTATAAGCCAGGAGATAAAGTCCTCCT
GCTTCACCTCGAGGAAGGAAAGGATTTGGAATACCATCTAGATCCAAAGACCAAGGAGCTGCCTCACTTACGAAATCCTGACATACTTGT
TGGTGAAAATGACCTCACAGCCCTCAGCTATCTTCATGAGCCTGCTGTGCTCCATAATCTCAGAGTCCGCTTTATTGATTCCAAACTTAT
TTATACGTATTGTGGTATAGTCCTAGTAGCTATAAATCCCTATGAACAGCTGCCTATTTATGGAGAAGATATTATTAATGCATACAGTGG
TCAGAACATGGGTGATATGGATCCACATATCTTTGCAGTAGCTGAAGAAGCTTACAAGCAAATGGCCAGAGATGAACGAAATCAGTCCAT
CATCGTAAGTGGAGAGTCTGGGGCAGGAAAAACAGTCTCAGCTAAGTATGCCATGCGATACTTTGCAACTGTGAGTGGTTCTGCCAGTGA
GGCCAATGTGGAGGAAAAGGTCTTGGCCTCCAACCCCATCATGGAGTCCATTGGAAATGCTAAAACAACCAGGAATGATAATAGCAGCCG
TTTTGGGAAGTATATTGAGATTGGTTTTGATAAGAGATATCGAATCATTGGTGCCAATATGAGAACTTATCTTTTAGAGAAATCCAGAGT
GGTATTCCAGGCAGAAGAGGAGAGAAACTATCATATCTTCTATCAGCTTTGTGCCTCAGCAAAGTTACCTGAATTTAAAATGCTACGATT
AGGAAATGCAGATAACTTTAATTACACAAAACAAGGAGGCAGTCCTGTGATTGAAGGAGTGGATGATGCAAAGGAGATGGCACATACTAG
GCAGGCCTGCACTTTGCTAGGAATTAGTGAATCTCATCAAATGGGAATTTTCCGAATACTTGCTGGCATCCTTCACTTAGGCAATGTTGG
ATTTACATCCCGAGATGCAGACAGCTGCACAATACCTCCCAAGCATGAACCTCTCTGCATCTTCTGTGAACTCATGGGTGTGGACTATGA
GGAGATGTGTCACTGGCTCTGCCATCGGAAACTGGCTACTGCCACAGAGACATACATCAAGCCCATCTCCAAGCTGCAGGCCACAAATGC
CCGCGATGCTTTGGCCAAGCACATCTATGCCAAGCTCTTTAACTGGATTGTAGATAATGTCAATCAGGCTCTCCATTCTGCTGTCAAACA
GCACTCTTTTATTGGTGTGCTAGACATTTACGGATTTGAAACATTTGAGATAAATAGTTTTGAACAGTTTTGCATAAATTATGCAAATGA
AAAACTACAGCAACAATTCAATATGCATGTCTTCAAATTGGAGCAAGAAGAATATATGAAGGAACAAATTCCATGGACACTCATAGATTT
TTATGATAATCAGCCTTGTATTAATCTTATAGAATCAAAACTAGGCATTCTAGATTTACTGGATGAGGAATGCAAGATGCCTAAAGGCAC
AGATGACACCTGGGCCCAAAAATTGTACAACACACATTTGAACAAATGTGCACTCTTTGAAAAGCCTCGTCTATCAAACAAAGCTTTCAT
CATCCAACATTTTGCTGACAAAGTGGAATACCAGTGTGAAGGATTTCTCGAAAAGAATAAAGACACCGTTTTTGAAGAACAAATTAAAGT
TCTTAAATCAAGCAAGTTTAAGATGCTACCAGAACTATTTCAAGATGATGAGAAGGCCATCAGTCCAACTTCAGCCACCTCCTCAGGGCG
CACACCCCTCACACGAACTCCTGCAAAGCCCACCAAAGGCAGACCAGGCCAAATGGCCAAAGAGCACAAGAAAACAGTGGGGCATCAGTT
CAGAAACTCCCTGCACCTGCTTATGGAGACACTCAATGCCACTACCCCTCACTATGTGCGCTGTATCAAGCCTAATGACTTCAAGTTCCC
ATTCACGTTTGATGAGAAGAGGGCAGTGCAGCAGCTGAGAGCATGTGGTGTCCTGGAAACCATCCGAATCAGTGCGGCCGGTTTCCCCTC
ACGGTGGACTTACCAAGAATTTTTCAGCCGCTACCGTGTCCTAATGAAGCAGAAAGATGTGCTGAGTGACAGAAAGCAAACATGCAAGAA
TGTGTTAGAGAAACTGATACTGGACAAGGACAAATACCAGTTTGGTAAGACAAAGATCTTTTTCCGTGCCGGTCAAGTGGCCTATCTAGA
AAAATTGAGAGCTGACAAACTGAGAGCTGCCTGCATCCGGATCCAGAAGACCATCCGAGGGTGGCTGCTGAGAAAGAAGTACCTACGCAT
GCGGAAGGCAGCCATCACCATGCAGAGATACGTGCGGGGCTACCAGGCCCGATGCTATGCTAAGTTTCTGCGCAGAACCAAGGCAGCAAC
CATCATTCAAAAGTACTGGCGCATGTATGTGGTCCGCAGGAGGTACAAGATTAGACGAGCTGCCACTATCGTTCTTCAGTCTTACTTGCG
AGGCTTCTTGGCCAGAAATAGGTATCGCAAGATACTCCGTGAGCACAAAGCAGTCATCATTCAGAAGCGAGTCCGGGGCTGGCTGGCCCG
CACACACTACAAGAGGAGCATGCATGCCATCATCTACCTTCAGTGCTGCTTCAGGCGGATGATGGCCAAGCGTGAGCTAAAGAAGCTCAA
AATCGAGGCTCGCTCAGTGGAGCGCTATAAGAAGCTGCACATCGGCATGGAGAACAAGATCATGCAGCTGCAGCGCAAAGTTGATGAGCA
GAACAAAGACTACAAATGCCTTGTGGAGAAACTAACCAATCTGGAAGGAATATACAACTCTGAGACTGAGAAACTACGAAGTGACTTAGA
ACGTCTTCAACTAAGTGAAGAGGAAGCGAAAGTTGCCACTGGGCGGGTCCTTAGTCTGCAGGAAGAAATTGCCAAGCTCCGGAAAGACCT
GGAGCAAACTCGTTCAGAGAAAAAATGCATTGAGGAACATGCAGATCGATACAAACAAGAAACAGAGCAGCTGGTATCAAATCTGAAGGA
AGAAAATACTTTGCTGAAGCAAGAAAAAGAAGCCCTCAATCACCGCATCGTGCAGCAGGCTAAGGAGATGACAGAAACTATGGAGAAGAA
GTTAGTAGAAGAAACGAAACAACTGGAACTCGACCTTAATGATGAAAGGCTGAGATATCAGAACCTTCTGAATGAGTTCAGTCGCCTGGA
AGAAAGATATGATGACCTCAAGGAAGAGATGACCCTTATGGTGCATGTGCCTAAGCCTGGACACAAGAGAACAGACTCCACCCACAGCAG
CAACGAGTCTGAATATATCTTTAGCTCTGAAATTGCAGAAATGGAAGACATTCCATCAAGGACAGAGGAACCAAGTGAGAAGAAGGTACC
TCTGGACATGTCATTGTTCCTTAAGCTCCAGAAGCGGGTCACAGAGCTGGAGCAGGAGAAGCAGGTGATGCAGGATGAGCTGGACCGCAA
GGAGGAGCAGGTGCTCCGCAGCAAGGCCAAGGAAGAAGAAAGACCACAAATTAGAGGTGCAGAACTGGAATATGAGTCACTCAAGCGTCA
AGAACTAGAATCAGAAAACAAAAAACTGAAGAATGAGCTAAATGAGTTGCGCAAGGCCCTCAGTGAGAAAAGTGCCCCAGAGGTGACCGC
CCCAGGTGCACCTGCCTACCGTGTCCTCATGGAGCAGCTGACCTCTGTGAGCGAGGAGCTTGATGTCCGCAAGGAGGAAGTCCTCATCTT
AAGGTCTCAACTGGTGAGCCAGAAAGAGGCCATCCAACCCAAGGATGACAAGAATACAATGACAGATTCCACAATACTTTTGGAAGATGT
ACAAAAAATGAAAGATAAAGGTGAAATAGCACAAGCATACATTGGTTTGAAAGAAACAAATAGATCATCTGCTCTGGATTACCATGAGTT
GAATGAGGATGGAGAGCTGTGGCTGGTTTATGAAGGGTTAAAACAAGCCAACAGGCTCCTGGAATCCCAGCTGCAGTCACAGAAGAGGAG
CCATGAGAATGAGGCCGAGGCCCTCCGTGGGGAGATCCAGAGCCTGAAGGAGGAGAACAACCGACAGCAGCAGCTGCTGGCCCAGAACCT
GCAGCTGCCCCCAGAGGCCCGCATTGAGGCCAGCCTGCAGCACGAGATCACCCGGCTGACCAACGAAAACTTGGATTTGATGGAACAACT
TGAAAAACAGGATAAGACGGTCCGTAAACTGAAAAAACAACTGAAAGTATTTGCCAAAAAAATTGGCGAACTAGAAGTGGGCCAGATGGA
GAACATATCCCCAGGACAGATCATTGATGAACCCATCCGACCAGTCAACATTCCCAGGAAAGAAAAGGATTTCCAAGGGATGCTGGAATA
CAAGAAGGAGGATGAGCAAAAACTTGTTAAGAACCTGATTCTGGAACTGAAGCCACGTGGTGTAGCAGTCAATTTGATTCCAGGATTACC
GGCATATATCCTGTTCATGTGTGTTCGACATGCTGACTACCTGAATGATGATCAGAAAGTAAGGTCGTTGCTAACATCAACAATTAACAG
CATCAAAAAAGTATTGAAGAAAAGAGGTGATGATTTTGAAACCGTCTCCTTCTGGCTCTCTAACACATGCCGATTTTTGCACTGCTTGAA
ACAGTACAGTGGAGAAGAGGGCTTTATGAAGCACAACACATCTCGCCAGAATGAACACTGCCTCACCAATTTTGACCTGGCTGAGTATCG
GCAGGTGCTGAGTGACTTGGCCATTCAGATCTACCAGCAGCTCGTGCGGGTGTTAGAGAACATCCTTCAGCCAATGATTGTCTCAGGCAT
GCTGGAACATGAAACGATTCAGGGCGTGTCTGGGGTGAAGCCCACAGGGTTGAGAAAGCGAACCTCCAGTATCGCCGATGAGGGCACCTA
CACACTGGACTCCATCCTCCGGCAGCTCAACTCCTTCCACTCGGTCATGTGTCAGCATGGCATGGACCCTGAACTGATCAAGCAGGTGGT
CAAGCAGATGTTCTACATCATAGGGGCCATCACCCTGAACAACCTTCTCCTGCGGAAGGACATGTGCTCCTGGAGTAAAGGCATGCAGAT
CAGGTACAATGTCAGTCAACTGGAAGAATGGCTGCGTGACAAGAATCTGATGAATAGTGGGGCTAAAGAAACCCTGGAACCTCTCATTCA
GGCTGCTCAACTTTTGCAAGTGAAAAAGAAAACAGATGATGATGCAGAAGCCATTTGTTCTATGTGCAATGCTTTAACTACTGCCCAGAT
TGTGAAAGTGTTGAATTTGTATACTCCAGTTAATGAGTTTGAAGAAAGAGTCTCTGTGTCGTTCATTCGTACTATACAGATGCGTTTACG
AGACAGGAAAGACTCTCCCCAGCTGCTCATGGATGCTAAACACATCTTTCCTGTCACCTTTCCTTTCAACCCATCTTCCCTCGCACTAGA
AACCATCCAGATTCCAGCCAGCCTCGGCCTGGGCTTCATTTCACGGGTCTGAAAGTGATGTCCAGGCAAAAATTGACAATACATTTCTTG
CCCGAAATAAGAACCCATTATTTCCAGTGAGTTACTGAAAATACATTTTTAAAGAGAAAGTACTGATTATCTCCCAAATGAGAAGTCATT
AACTGGAAATCTCCCTAGAATACTTTCATCACTTTGGAAACAAAGATAGGCTCTTTCGTGCTGTGTTATCTTTATAGCAACACTCATCCT
TAACCAACTAGGTACCGTGAGTTTACATACAGGAGAATGATGGAAGGAAGGGAGGAAGGAAAGGAGGAGAAAAATGTGTCTTCAGCTGGC
AGCATTTATTTTAAATCCTTAGCACTGAGTTTGAATGGTATAAAAAGTATAACTTCCATAGATGAGCTGTTGTTAGGAAGGCACCAAAGA
ACCTCCTCTGCACTAAACAGGAGAATGGAAAGAAAAGTCTCCATTGAGTACATATCATGTCAGTTTAGTAATCAATTATGTTGATATTGT
TAAACTGGTTCAAAGAAATAAACTGGCAATATGTAAAGTAATTCCTCATTTGTGTCACTATGATATAGAGATATTAAAGGAATGTTGGTT
TGCTAAATAGTATAGATGTCCATTTGTACTATAGTTTACTGAGCATTTTAAATTGCTGCTACATACTGTCTTCTTAAAATGTAAGTGATA
TTAGGCACTACAATAAGTTTCTCTTGTCAATTCTGTTTACAATTCAATCAGATCACAGTTTTAACTGGATTATATGCAAATACCTACAGA
TTCACCTGCACAAGTAGCAGACACTGGAAAGTCATGTAGTAATATGACAAAATGCTTGACATTTAGGGGTAGGATTAGACAAAGTGGCTA
TTGTTGATGTCATTATTTATTCAGGATGTATTACATTGATGTGCTCATTAATTTTCCCTGGGTGGATATTGCGTCAGGGTACAGTGTTCT
GTGAAGTGACTTATTTTTAACTACCAGATCTGATTCCTTCAGTGCATATTTTCAACCTTGACAGGTTTTCTCTCTTCTTAATTTATTAAG
AATTAATCTCGGCTGGGCGCGGTGGCTCACGCCTGTAATCCCAGCACTTTGGGAAGCCAAGGTGGGCGGATCACTTCAGGTTAGGAGTTG
GAGACCAGCCTGGCCAACATGGCGAAACCCTGTCTCTACTAAAAATACAAAAATTAGCCGGGCGTGGTGGCACTTGCCTGTAATCCCAGC
TACTCGGGAGGCTGAGGCACGAGAATCGATTAAACCTGGGAGGCGGAGATTGCAATGAGATCGAACCACTGCACTCCAGCCTGGGTGACA
GAGAGAGACACTGCCTTGGAAAAAAAAAGAATCTCACTCACTATCTAGAGAGGATTGTCAGAATATTCACGATTCAGGTCTTGAAACTTT
GATTATGCAAAAGAAGGTATATAATAAATATTTCATTATGATTCAGTTTTTAAGGCTTTGCAGCTTCTATAAGTGTTCTCAGATGCCACT
AGATAATTTTAAAAGCATCATATTAGAAATACTTTAAGAAGACTTATATAAGAAATAGAAGATTGTTGAATTTTACAGAGGATTTGGTTC
ATTAAGACCCAGATTCTGTAAGTTTTCATTCTGAAATTCTAGTTAAACATATTCACCATTTTTCTTAGGAATCTTATACAATAAATCCTT
CAGGTTGCACAAAAGCAAATTATTAGTTTTCATTAGAAACTCTGGTTCTGAATTACAATCATAGGTTATATAAATTTAACTGTTAGATGG
TCTATAAATCTTATTAAAATATGTGCAATATTTATGGAAGTCAAACAGCTTCATATCAGTGATAAAGATTGTTATTAAAAGATAAATACT
GTCTGTTAATTTACATGGGCCTCAAGTTCCTCGTTTATAAAATAAGAGAGTTGGACACTGATTCTTAACATCTCCTCCACATTTAAAATT
CTCTCTTCTCAGCCCTTAGATTCTAGAGAGAAAAAGCTGCAGTTACTCAGTAAGTCCATTCTCTGATGGAAAGACCAGTGTGTAGTGCCT
GTCAATTCCTTAGGATTAATCAAATGTAAAATCACAAGTTTGTGTAGCTGTAACCTTTCTTAAATGTACATGATTTATGTACATGCTTTT
AGAAGGTCCTACTATATTTGTATTATAATTAGTTTAAGTAATTTTTATTACATCATGTATTGCTTTATTCAGTTTGAATACATTTATTTA
TTTATTTGCAGTATCAACCAGAAACACTACCAATTGCATCAAATTCTCCCAGTTTTTCCTGGTTGTCAATGCGGTTTTCAATGCACAATT
AAGTCATAGCCATTTGGTTCGTACCAAATGTGTCAGAATCTAACAGCATCCGATAGGCTGTAAGTTGGGGAGTTGCTAAGAAAATGCAAC
GTGGTACAGGCTGTCCGCCTCAGCCCTGGAAATCTCCCAGACCTCCCCCAGCTTCATCCTGTGTAGCACGACTCAACGTGCACCCTGAAT
CTTCTCAGGTCTTCCAGGTCATGCTGTAGCTGTCACTGCCATGCAGCCCTTTTTTTTACTCCGGACAGCTCATGTACTGAAGCGTCATGA
AAGAAAGGCTGTGGTCTGAGCCCTTCTCTCCCATCTCCTGTCTTTGTCCTGTCAAGTGCTGGAGCCAGAGCTCCTACAGCTGCCCTTGGT
GGTTTCTCCTGTTCAGCGATGGTGGCACAAAGGTTCTGCTATTCCAGGGCTCCAGCTTCCTCCCAGGTCTACCCAGAGCTCCAGATGGGG
GTCTGAATTAACCTCTCTTGGTGGCCTGGAGATTTTTAGTCATTGACAAGAATACCTTGTAACCAGGGAACCCCAAGGCCCAGTAAATGA
TTCTGTATACCATTTTCTTGAAGGTACAAGAAGATTCTGCCGACTATGGGGATCTTTGGGCCAGTTTGAGGATTGCTTTCCCTCTGAGGT
TCTTTCTCTCTGTCAGCCACACTTTCTCACCCAACTTCAGACACACCCTGCCAGCCTTTCCCCTACTCATTCACTCTTCCCCTTCCCTCA
ACTTAATCGTCTATCCCGTTGCCTGCTGTTTGACTGTGCACTGAAGGCAGGTGGATGGAGTCAGTCCTCAGTTGCCCCTGCTGGCCTTCC
TGGTGCTTACCATCAGCCCAATCTTTGCACAGTCCTTGTTGTTCTTACTTCTCTGCATGCATTCCTTCAGAAGATCAGTCATCAACTTTT
TCTTAATTCCTCTGTGACACACAATGGGAATTCAAAGGAAGAGATCTTAAAAGTCACAACAGTTCTTTATCTTAATAATCCCCTCCCCAT
TCACCTTACTACATGCAGACTCACCTCACACCCTTACAACTTGAAGCTGAAAATTTAAAAGTAATTTCCCTTTTTGCAGCTTTTCCTCAG
GTTAAGGCTTTGATCTGCCTGAGAGTAACTCTAAAAGGAGGGAAGATAAATATGGGATAAAATCCACAAAGTGTAGCTTCTAATTCCTTT
GGAAGTTTAAAAAATTTCCACATATCTGATGCTTCTTTTGTCAGGTGCAGAAGCACAAAAACATATTCCGAAGCCAACTGATAGGGAATT
TGGGGATTATTGTCAGTTTGGAGAATTTGCTGTGTTATTTCTTCATTTCCATGGATAGCTCATAGTTGGCTCTTTCTGGGTGAGTAATTA
TGTGTAATATAGATCAAATCTTTTACTAAGGTTACAGCTACATGTTAGGGGAGGCTATGAAAATACTATATTATTATAATTTCAGTGCAG
TGATTGTTGTGAGAAATAACTTTCATGGTAACCCTAGGAAAATGGGCACCTGCCACCATCCTGAGAAGTCCTCACACAATGCCCTTTCTC
TCTTACACACACACACACACACATACACACACACACACCCCCGTCACTAATTCATAGAGTTCCTTAGCAGGCATAGTCAAGGATCCTCTG
GGTAATGTCAGCTGCTTAGTGATAAAACAGAGCCAAAACTAGTGCATCCTGTTGAAAGTAATGCAGAAACAGTACCTGGGTCCAGATATG
CTTTCCTGCGGCGCTTTCCTCTGTTACCTCGTTTCATCCTCACAGCAGCATGGACGGTAGGTGGGGTCGCTTCTACAATCATTTCTGATG
ATAGCTTGGGAATAGAGATAGGGGCAGTGACTTGCCTGATGTCGCACAGCCCTCTGGCTGTCCTGCTTTCCCATATGGAGCAGTGGTGGT
GTGGGCACCTGTGATGCAGGAGACTTTAAAAATGTCGTGAGGTCACGTGCTGCCCCTCCTGGTACGTGTGGAATGCCCCTGGCCAGCAAG
GGGTGCTTTTTTATCAGAGTTGGCAGCTGGCATGTGGGAACCGAGCAAGTGCTGCGTACCAAGTTACTTGTTTTAAGGAGACCAAGTGCT
CAGCGCCAGGTGGTTTTCTTTTTTGTCATAGTTACTTGCTATAACTCAGCTTGACTTCTGTCATGAATCAGTGCTCTCTGGGAGGATGCA
ATACTCTGTTTGGGCATTAATTGGTAGCAGGTTGTCTCAACCAAAAAGACAGGAAACAGCAAAAGCCTCTCTGAAATTAAGAGGAAAGTT
ACTCTCCCCACACCCATCAGAGTCTTTATTGGAGCCACCAGGTGAGCTGTGCAGCCTGGACAGGCCTGCAGCTATAGGCCACCTTCCCAG
TTTAGGTCCTCAGCACAGGGGAGCCCAAGTCACTGGGTGCCTTCCGAGGGCTGTCACTGGGCAGGCCATATACAAGTCAGTGTGTGCGTG
GGCACTGCAGTGTGTGCATGCCGTAGGTGTTGATGGGTGCTAGGAGGGGTGTCGTGTGCATGCGCGTTGAAGAGGATCTGTATTGCCGTG
ACCTCTGTTCATGGATGAGTGCATTGTAATTTGTTCTCAGGCTGTGCTGTGAGGGCCGCCTTAACCCTTGCTCCCTTCCCTTCTAGAGCT
GCCTTAAGTTCTCCAGAACTTTTCTTCTGTAAAGGATATCTTGCCTGGAAGGGATATCTTGCCCTGTTTCTCAAGGTTTTGTGAGAGTTT
TGACTGGATGTGGCCCTGCATGACCCTCCTTCTCCTGTACTTCCTCTTTCCTTTCCAAATGGGAATTAGAACTGTGGGGCAGCAACAGTC
TCAGAGCCAGTGAGAGGCCAGCTTAGAGAATGCTTCTGAGTTAGTGGGACTCTGTGTCACAAGTAAGCAAATGAATATATGAAAGAAATT
ATGGAGATAAGTTAGATTCTTGGTAATACTTAAATGTCTTGCTTTCTACTAACCTTTTGTTACTAAAGGTAAAGGGTATAACTCAAACTT
TTTGTGGACATTCTTTTCAAAATTTTTTAAGAACCCTGTACTATAAAAGGTTGAGTAAAAACAGGAAAGCGTGCTATAAGTTCAAATCTG
TTGTATTACCCTAAATTAGATAAACCAACCTGAATTATAGTAGATTTCTCAATAGATGAGGAACTGAAAAATACTATGTAAAATATCTTC
CAAAATGCTTTTTATACTTTTTTTATTTGTAATTTGGTCTATCTAAAATGTTCGTTAGCTTAACTTAATGGGCGTTATTGGATTCATATG
ACTAACGTTTCCTCAGTATTGTAATGCTTGAAATATTTGAAAGAAAAAATGTTGTTTTTTAGTTGAAACTGGTATATATAATTCAGTGCT
TGGCAGGTTAGTATATTTTTATGCATTTTTCAGAGTCAGCAGTTTCAAATCTTATTGTTATCATGTTATAAAATTTTAGCCCACATTTCA
GGCTCCGTAAATCATTTGAGCCATTATTTTTTCCCAACAAATGGTGAATTTTTTCTTTAAATGTGGATATATATGTTGTAATTTATGATT
CCTGGTTATGTATTTTTGTGGGATCCTGCAGTAAAATTGACTTTTTTGTGTCTTTGGGAGATTTAAATTGCGCTAACAGTGTTGCGCAAA
AATGAGTTCATGCCATTTAACATATTGTATTTTAATTATTAACTGTATTAATTTACTATGAAATGGACATCCTTTTAACTAAAATGGAAT
TGAACATTGCAGTTTTCAAATATTTTTCCTTGTTGGGTCTGGAAAAGGAATTCTACTTTGATCTGCATAGAAAATTTTGATACAATTTTT
TGAAAGTTCTTAGGTGAAACATTTACCCATTAAAAAGGAAGCAGAAATACTGAGACATGAAAGGCATTATCAACTAACTCTAGACTCTAG
AACCCATTCTAGCATATCTCACGTGCAATTTTTAAAAATAAGTTAATAATTCATCTCATATCAACAAAAGCCTTTGAAACATGGGTTTTC
ACTAGATATCACCTAGTGCTAAGATAAAAACCAAAACAATATCAGAATTACATTTATGCTCTAAATTTGTAGTTGTCCATTGTTGTGCTT
AGTAAATGTGTGTCATTAATGCTGTATTCTCCTAGCTATTATGGAAACTTGTTTAAATAAAGATATGGATATAAAAAAGAAAAAAACTGA
AGGCACCTATGACTTACCTTACTGGGACCGGGCAGGTTTTTATTTAATGGTCTCTTTGGCTTGCCGTCACAATGAAGGTTGGTGGAAAGG
AATGAAGCAGTTTCTTCCTGCAAAAGCAGTGGACCATGAGGAAACCCCAGTTCGCTATAGCAGCAGCGAAGTTAATCACCTGAGTCCAAG
AGAAGTCACCACAGTGCTGCAGGCTGACTCTGCAGAGTATGCTCAGCCACTGGTAGGAGGAATTGTTGGTACACTTCATCAAAGATCTAC
CTTTAAACCAGAAGAAGGAAAAGAAGCAGGCTATGCAGACCTAGATCCTTACAACTCACCAGGGCAGGAAGTTTATCATGCCTATGCTGA
ACCACTCCCAATTACGGGGCCTGAGTATGCAACCCCAATCATCATGGACATGTCAGGGCACCCCACAACTTCAGTTGGTCAGCCCTCCAC
ATCCACTTTCAAGGCTACGGGGAACCAACCTCCCCCACTAGTGGGAACTTACAATACACTTCTCTCCAGGACTGACAGCTGCTCCTCAGC
CCAGGCCCAGTATGATACCCCGAAAGCTGGGAAGCCAGGTCTACCTGCCCCAGACGAATTGGTGTACCAGGTGCCACAGAGCACACAAGA
AGTATCAGGAGCAGGAAGGGATGGGGAATGTGATGTTTTTAAAGAAATCCTTTGAAGATGATGCTGCTTTTTACAAAGCATCGTTTTAAA
GCACATGGCCTTTTTTTTTTAATTATTAGTGGTAGTAATATATAGAATGTATTACATAACTGTCACTGAAGTGGTTGGGGAAAATGTGGT
GACTGAGGTACAGGAAACTACTAATCTTGCCATCTTGCTTTAAGGTGTTATGGTGGCACAGTTACTGCTCGCCTGTTAAATTTCAAATGT
CCTGTTTGATACTACTGTAGAACACTATTTTTAATACAGAAAAAGCTCCCTATAATGCACTTCAGAGAAATTAAAAATCACAGAGTATTT
ATTACCAATGCTGCAGGTACATTAATGAACTCGAGATGGCTCTGTAAGCCTGACTGGCAATAACGCACGGTACTGTTCTTGAAATACCTA
ATGGCTTGAAATTCTAGTCTGTTTGTGAAAGATGGGTACTATCATGATTTCCTCTTCTATTCCTATATTCTTTTCTGGATTTTTTTTAAT
AATTAGTGATATAAGCATTGTTTTTATTGCAGCCATATCCACTTATCCATCTTAAGATCTGTAGCTGGGATTTTCTGACTTGTAATGAGC
AGGGGGATTGCTTTTTCACTTTGTGACACTCTTTAGAGCTTTAATGCTTCACAGTATATGGCCTGGTCTCATCCTTGCGTGTTCCACTTG
AGGCCCTTTGGTGTCTTGCCCCATTCTTGTGTTTATAAAATGTTTGAGTATTTCTGATGAGTGATGCTTGCCTTAGTCTCATGAATTCAG
ATCCCTTCATGTCCTTTAAGTATGCTCCTCAATGTGTAAACAGGAACAACTTTATGATTTGAAAGCTTTAAAGGAGATTCTTCTCCCACC
CCCAACTTTATTTGCAATGGGATTTTTCCTAGGAGAGTTATGAAAAGTTGAAGGCTTCTAAGGGAATACTGTAAACATGACCCACTTATA
TTTATCACAGTGAAAGGCAAAATTATTCACTCAGAAGTAATATAAATTACCTCTTTAAAAAGTAACCAGAATTTGTCCTTTTTGGTTTTA
TACATTCACAAACATATACATTTTTCTTGAGTCTCAAGGTATTTTATATTTTTAGTCAGAAAAAATAATTTTTCATTTCAGTTTTCCATA
AACTGTTACACAAAATATAAACCTAACGTGTATTTTTCAGGACTGCGTGATCGTGCACTTTGTGTGGTAAGAGGTTTGAGTAGTCCTATA
TGTCACCTAGGGAACAGACATTATAGCTTACTAGCAAATGAATATTCATGCCTTGTTTTTGATACCTCCTGGCAGCTTCCATGTCACCAC
TTGTTCATACCTGCCCAGAGCTAGTTTTAGACATGGCAAAATAGAAATCATCTGTAATTTATTAGCTAACAATGTAAAACCATCTTTTAA
AGCCTTCAGACTGTCAAGACGACATGAGCAGCTCACCATATGATAAAAATACATAAATTTGACATTCCCTCTTCCATAAACCTTTGTTTG
TAGATTTAATGTTGAACAGTACTTTTCCATAAAGTTCTAGTCACTTCTGTTGGCCTGAGCCACCAGATTATGATGTTGCCAGAATTCACT

>56706_56706_4_MYO5A-DCBLD2_MYO5A_chr15_52599483_ENST00000399231_DCBLD2_chr3_98520493_ENST00000326857_length(amino acids)=1855AA_BP=
MAASELYTKFARVWIPDPEEVWKSAELLKDYKPGDKVLLLHLEEGKDLEYHLDPKTKELPHLRNPDILVGENDLTALSYLHEPAVLHNLR
VRFIDSKLIYTYCGIVLVAINPYEQLPIYGEDIINAYSGQNMGDMDPHIFAVAEEAYKQMARDERNQSIIVSGESGAGKTVSAKYAMRYF
ATVSGSASEANVEEKVLASNPIMESIGNAKTTRNDNSSRFGKYIEIGFDKRYRIIGANMRTYLLEKSRVVFQAEEERNYHIFYQLCASAK
LPEFKMLRLGNADNFNYTKQGGSPVIEGVDDAKEMAHTRQACTLLGISESHQMGIFRILAGILHLGNVGFTSRDADSCTIPPKHEPLCIF
CELMGVDYEEMCHWLCHRKLATATETYIKPISKLQATNARDALAKHIYAKLFNWIVDNVNQALHSAVKQHSFIGVLDIYGFETFEINSFE
QFCINYANEKLQQQFNMHVFKLEQEEYMKEQIPWTLIDFYDNQPCINLIESKLGILDLLDEECKMPKGTDDTWAQKLYNTHLNKCALFEK
PRLSNKAFIIQHFADKVEYQCEGFLEKNKDTVFEEQIKVLKSSKFKMLPELFQDDEKAISPTSATSSGRTPLTRTPAKPTKGRPGQMAKE
HKKTVGHQFRNSLHLLMETLNATTPHYVRCIKPNDFKFPFTFDEKRAVQQLRACGVLETIRISAAGFPSRWTYQEFFSRYRVLMKQKDVL
SDRKQTCKNVLEKLILDKDKYQFGKTKIFFRAGQVAYLEKLRADKLRAACIRIQKTIRGWLLRKKYLRMRKAAITMQRYVRGYQARCYAK
FLRRTKAATIIQKYWRMYVVRRRYKIRRAATIVLQSYLRGFLARNRYRKILREHKAVIIQKRVRGWLARTHYKRSMHAIIYLQCCFRRMM
AKRELKKLKIEARSVERYKKLHIGMENKIMQLQRKVDEQNKDYKCLVEKLTNLEGIYNSETEKLRSDLERLQLSEEEAKVATGRVLSLQE
EIAKLRKDLEQTRSEKKCIEEHADRYKQETEQLVSNLKEENTLLKQEKEALNHRIVQQAKEMTETMEKKLVEETKQLELDLNDERLRYQN
LLNEFSRLEERYDDLKEEMTLMVHVPKPGHKRTDSTHSSNESEYIFSSEIAEMEDIPSRTEEPSEKKVPLDMSLFLKLQKRVTELEQEKQ
VMQDELDRKEEQVLRSKAKEEERPQIRGAELEYESLKRQELESENKKLKNELNELRKALSEKSAPEVTAPGAPAYRVLMEQLTSVSEELD
VRKEEVLILRSQLVSQKEAIQPKDDKNTMTDSTILLEDVQKMKDKGEIAQAYIGLKETNRSSALDYHELNEDGELWLVYEGLKQANRLLE
SQLQSQKRSHENEAEALRGEIQSLKEENNRQQQLLAQNLQLPPEARIEASLQHEITRLTNENLDLMEQLEKQDKTVRKLKKQLKVFAKKI
GELEVGQMENISPGQIIDEPIRPVNIPRKEKDFQGMLEYKKEDEQKLVKNLILELKPRGVAVNLIPGLPAYILFMCVRHADYLNDDQKVR
SLLTSTINSIKKVLKKRGDDFETVSFWLSNTCRFLHCLKQYSGEEGFMKHNTSRQNEHCLTNFDLAEYRQVLSDLAIQIYQQLVRVLENI
LQPMIVSGMLEHETIQGVSGVKPTGLRKRTSSIADEGTYTLDSILRQLNSFHSVMCQHGMDPELIKQVVKQMFYIIGAITLNNLLLRKDM
CSWSKGMQIRYNVSQLEEWLRDKNLMNSGAKETLEPLIQAAQLLQVKKKTDDDAEAICSMCNALTTAQIVKVLNLYTPVNEFEERVSVSF

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Fusion Gene PPI Analysis for MYO5A-DCBLD2


check button Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in

ChiPPI page.


check button Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160)
HgeneHgene's interactorsTgeneTgene's interactors


check button - Retained PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenStill interaction with


check button - Lost PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


check button - Retained PPIs, but lost function due to frame-shift fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


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Related Drugs for MYO5A-DCBLD2


check button Drugs targeting genes involved in this fusion gene.
(DrugBank Version 5.1.8 2021-05-08)
PartnerGeneUniProtAccDrugBank IDDrug nameDrug activityDrug typeDrug status

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Related Diseases for MYO5A-DCBLD2


check button Diseases associated with fusion partners.
(DisGeNet 4.0)
PartnerGeneDisease IDDisease name# pubmedsSource