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 | Fusion Gene Summary |
| Fusion Gene ORF analysis |
| Fusion Genomic Features |
| Fusion Protein Features |
| Fusion Gene Sequence |
| Fusion Gene PPI analysis |
| Related Drugs |
| Related Diseases |
Fusion gene:NAA20-MYO1E (FusionGDB2 ID:56960) |
Fusion Gene Summary for NAA20-MYO1E |
 Fusion gene summary |
| Fusion gene information | Fusion gene name: NAA20-MYO1E | Fusion gene ID: 56960 | Hgene | Tgene | Gene symbol | NAA20 | MYO1E | Gene ID | 51126 | 4643 |
| Gene name | N-alpha-acetyltransferase 20, NatB catalytic subunit | myosin IE | |
| Synonyms | NAT3|NAT3P|NAT5|NAT5P|dJ1002M8.1 | FSGS6|HuncM-IC|MYO1C | |
| Cytomap | 20p11.23 | 15q22.2 | |
| Type of gene | protein-coding | protein-coding | |
| Description | N-alpha-acetyltransferase 20N-acetyltransferase 3 homologN-acetyltransferase 5 (ARD1 homolog, S. cerevisiae)N-acetyltransferase 5 (GCN5-related, putative)N-acetyltransferase 5, ARD1 subunit (arrest-defective 1, S. cerevisiae, homolog)N-terminal acety | unconventional myosin-IeMYO1E variant proteinmyosin-ICunconventional myosin 1E | |
| Modification date | 20200320 | 20200313 | |
| UniProtAcc | P61599 | Q12965 | |
| Ensembl transtripts involved in fusion gene | ENST00000484480, ENST00000310450, ENST00000334982, ENST00000398602, | ENST00000288235, ENST00000558814, | |
| Fusion gene scores | * DoF score | 8 X 7 X 3=168 | 10 X 11 X 5=550 |
| # samples | 8 | 12 | |
| ** MAII score | log2(8/168*10)=-1.0703893278914 possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs). DoF>8 and MAII<0 | log2(12/550*10)=-2.1963972128035 possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs). DoF>8 and MAII<0 | |
| Context | PubMed: NAA20 [Title/Abstract] AND MYO1E [Title/Abstract] AND fusion [Title/Abstract] | ||
| Most frequent breakpoint | NAA20(20003124)-MYO1E(59553708), # samples:1 | ||
| Anticipated loss of major functional domain due to fusion event. | |||
| * DoF score (Degree of Frequency) = # partners X # break points X # cancer types ** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10) |
| Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez |
| Partner | Gene | GO ID | GO term | PubMed ID |
| Fusion gene breakpoints across NAA20 (5'-gene) * Click on the image to open the UCSC genome browser with custom track showing this image in a new window. |
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| Fusion gene breakpoints across MYO1E (3'-gene) * Click on the image to open the UCSC genome browser with custom track showing this image in a new window. |
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| Fusion gene information from two resources (ChiTars 5.0 and ChimerDB 4.0) * All genome coordinats were lifted-over on hg19. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| Source | Disease | Sample | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| ChimerDB4 | STAD | TCGA-HU-A4GJ-01A | NAA20 | chr20 | 20003124 | + | MYO1E | chr15 | 59553708 | - |
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Fusion Gene ORF analysis for NAA20-MYO1E |
| Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| ORF | Henst | Tenst | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| 3UTR-3CDS | ENST00000484480 | ENST00000288235 | NAA20 | chr20 | 20003124 | + | MYO1E | chr15 | 59553708 | - |
| 3UTR-intron | ENST00000484480 | ENST00000558814 | NAA20 | chr20 | 20003124 | + | MYO1E | chr15 | 59553708 | - |
| 5CDS-intron | ENST00000310450 | ENST00000558814 | NAA20 | chr20 | 20003124 | + | MYO1E | chr15 | 59553708 | - |
| 5CDS-intron | ENST00000334982 | ENST00000558814 | NAA20 | chr20 | 20003124 | + | MYO1E | chr15 | 59553708 | - |
| 5CDS-intron | ENST00000398602 | ENST00000558814 | NAA20 | chr20 | 20003124 | + | MYO1E | chr15 | 59553708 | - |
| In-frame | ENST00000310450 | ENST00000288235 | NAA20 | chr20 | 20003124 | + | MYO1E | chr15 | 59553708 | - |
| In-frame | ENST00000334982 | ENST00000288235 | NAA20 | chr20 | 20003124 | + | MYO1E | chr15 | 59553708 | - |
| In-frame | ENST00000398602 | ENST00000288235 | NAA20 | chr20 | 20003124 | + | MYO1E | chr15 | 59553708 | - |
| ORFfinder result based on the fusion transcript sequence of in-frame fusion genes. |
| Henst | Tenst | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand | Seq length (transcript) | BP loci (transcript) | Predicted start (transcript) | Predicted stop (transcript) | Seq length (amino acids) |
| ENST00000334982 | NAA20 | chr20 | 20003124 | + | ENST00000288235 | MYO1E | chr15 | 59553708 | - | 6005 | 359 | 29 | 3538 | 1169 |
| ENST00000310450 | NAA20 | chr20 | 20003124 | + | ENST00000288235 | MYO1E | chr15 | 59553708 | - | 5811 | 165 | 87 | 3344 | 1085 |
| ENST00000398602 | NAA20 | chr20 | 20003124 | + | ENST00000288235 | MYO1E | chr15 | 59553708 | - | 6323 | 677 | 617 | 3856 | 1079 |
| DeepORF prediction of the coding potential based on the fusion transcript sequence of in-frame fusion genes. DeepORF is a coding potential classifier based on convolutional neural network by comparing the real Ribo-seq data. If the no-coding score < 0.5 and coding score > 0.5, then the in-frame fusion transcript is predicted as being likely translated. |
| Henst | Tenst | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand | No-coding score | Coding score |
| ENST00000334982 | ENST00000288235 | NAA20 | chr20 | 20003124 | + | MYO1E | chr15 | 59553708 | - | 0.000528998 | 0.999471 |
| ENST00000310450 | ENST00000288235 | NAA20 | chr20 | 20003124 | + | MYO1E | chr15 | 59553708 | - | 0.000423059 | 0.999577 |
| ENST00000398602 | ENST00000288235 | NAA20 | chr20 | 20003124 | + | MYO1E | chr15 | 59553708 | - | 0.000737965 | 0.99926203 |
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Fusion Genomic Features for NAA20-MYO1E |
| FusionAI prediction of the potential fusion gene breakpoint based on the pre-mature RNA sequence context (+/- 5kb of individual partner genes, total 20kb length sequence). FusionAI is a fusion gene breakpoint classifier based on convolutional neural network by comparing the fusion positive and negative sequence context of ~ 20K fusion gene data. From here, we can have the relative potentency of the 20K genomic sequence how individual sequnce will be likely used as the gene fusion breakpoints. |
| Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand | 1-p | p (fusion gene breakpoint) |
| Distribution of 44 human genomic features loci across 20kb length fusion breakpoint regions. We integrated a total of 44 different types of human genomic feature loci information across five big categories including virus integration sites, repeats, structural variants, chromatin states, and gene expression regulation. More details are in help page. |
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| Distribution of 44 human genomic features loci across 20kb length fusion breakpoint regions that are ovelapped with the top 1% feature importance score regions. More details are in help page. |
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Fusion Protein Features for NAA20-MYO1E |
| Four levels of functional features of fusion genes Go to FGviewer search page for the most frequent breakpoint (https://ccsmweb.uth.edu/FGviewer/chr20:20003124/chr15:59553708) - FGviewer provides the online visualization of the retention search of the protein functional features across DNA, RNA, protein, and pathological levels. - How to search 1. Put your fusion gene symbol. 2. Press the tab key until there will be shown the breakpoint information filled. 4. Go down and press 'Search' tab twice. 4. Go down to have the hyperlink of the search result. 5. Click the hyperlink. 6. See the FGviewer result for your fusion gene. |
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| Main function of each fusion partner protein. (from UniProt) |
| Hgene | Tgene |
| NAA20 | MYO1E |
| FUNCTION: Catalytic subunit of the NatB complex which catalyzes acetylation of the N-terminal methionine residues of peptides beginning with Met-Asp, Met-Glu, Met-Asn and Met-Gln. Proteins with cell cycle functions are overrepresented in the pool of NatB substrates. Required for maintaining the structure and function of actomyosin fibers and for proper cellular migration. {ECO:0000269|PubMed:18570629}. | FUNCTION: Myosins are actin-based motor molecules with ATPase activity. Unconventional myosins serve in intracellular movements. Their highly divergent tails bind to membranous compartments, which are then moved relative to actin filaments. Binds to membranes containing anionic phospholipids via its tail domain. Required for normal morphology of the glomerular basement membrane, normal development of foot processes by kidney podocytes and normal kidney function. In dendritic cells, may control the movement of class II-containing cytoplasmic vesicles along the actin cytoskeleton by connecting them with the actin network via ARL14EP and ARL14. {ECO:0000269|PubMed:11940582, ECO:0000269|PubMed:17257598, ECO:0000269|PubMed:20860408}. |
| Retention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at * Minus value of BPloci means that the break pointn is located before the CDS. |
| - In-frame and retained protein feature among the 13 regional features. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Protein feature | Protein feature note |
| Tgene | MYO1E | chr20:20003124 | chr15:59553708 | ENST00000288235 | 1 | 28 | 1051_1108 | 49 | 1109.0 | Domain | SH3 | |
| Tgene | MYO1E | chr20:20003124 | chr15:59553708 | ENST00000288235 | 1 | 28 | 695_724 | 49 | 1109.0 | Domain | IQ | |
| Tgene | MYO1E | chr20:20003124 | chr15:59553708 | ENST00000288235 | 1 | 28 | 730_922 | 49 | 1109.0 | Domain | TH1 | |
| Tgene | MYO1E | chr20:20003124 | chr15:59553708 | ENST00000288235 | 1 | 28 | 112_119 | 49 | 1109.0 | Nucleotide binding | ATP | |
| Tgene | MYO1E | chr20:20003124 | chr15:59553708 | ENST00000288235 | 1 | 28 | 581_591 | 49 | 1109.0 | Region | Actin-binding |
| - In-frame and not-retained protein feature among the 13 regional features. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Protein feature | Protein feature note |
| Hgene | NAA20 | chr20:20003124 | chr15:59553708 | ENST00000310450 | + | 2 | 5 | 2_157 | 26 | 112.0 | Domain | N-acetyltransferase |
| Hgene | NAA20 | chr20:20003124 | chr15:59553708 | ENST00000334982 | + | 2 | 6 | 2_157 | 26 | 179.0 | Domain | N-acetyltransferase |
| Tgene | MYO1E | chr20:20003124 | chr15:59553708 | ENST00000288235 | 1 | 28 | 19_692 | 49 | 1109.0 | Domain | Myosin motor |
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Fusion Gene Sequence for NAA20-MYO1E |
| For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. To have fusion amino acid sequence, we ran ORFfinder and chose the longest ORF among the all predicted ones. |
| >56960_56960_1_NAA20-MYO1E_NAA20_chr20_20003124_ENST00000310450_MYO1E_chr15_59553708_ENST00000288235_length(transcript)=5811nt_BP=165nt GGTTCCGCGGCGGCCACGCTCCGGGAGACTTCCGGCAGGGCGGGCGCGGGGTCTTGGCGAACGGTCTTCGGAAGCGGCGGCGGCGCGATG ACCACGCTACGGGCCTTTACCTGCGACGACCTGTTCCGCTTCAACAACATTAACTTGGATCCACTTACAGAAACTACATATATAGGATCT GTATTAATCTCAGTCAACCCTTTCAAGCAGATGCCATATTTTGGGGAAAAGGAAATTGAAATGTACCAAGGAGCGGCACAGTATGAAAAC CCACCACATATCTATGCCCTTGCAGATAATATGTACAGAAACATGATCATTGACAGAGAGAACCAGTGCGTCATTATCAGTGGTGAAAGT GGTGCTGGAAAAACAGTGGCTGCCAAATATATCATGAGCTACATCTCCAGAGTGTCTGGAGGAGGGACCAAAGTCCAGCACGTGAAGGAC ATTATCCTGCAGTCCAACCCGCTGCTGGAGGCCTTCGGGAACGCCAAGACCGTCCGGAACAACAACTCCAGCCGATTTGGAAAATACTTT GAAATCCAGTTCAGTCCAGGTGGGGAACCAGATGGTGGAAAGATCTCCAACTTCCTTCTGGAAAAATCTAGGGTGGTGATGAGGAACCCA GGAGAGCGGAGTTTTCACATATTTTACCAGCTCATCGAGGGCGCCTCTGCAGAGCAGAAACACAGCCTTGGCATCACCAGCATGGACTAT TATTACTACCTGAGCCTCTCGGGCTCATACAAGGTTGATGACATTGACGACAGGCGGGAGTTTCAGGAAACTCTGCACGCCATGAATGTG ATTGGGATCTTTGCAGAAGAGCAAACGCTGGTGTTGCAGATAGTGGCGGGTATTCTCCACCTGGGAAACATCAGCTTCAAAGAAGTTGGC AACTACGCGGCTGTGGAGAGTGAAGAGTTTTTAGCTTTTCCTGCATATCTGCTAGGGATAAACCAGGACCGGTTGAAAGAAAAGCTAACA AGCCGGCAGATGGATAGCAAGTGGGGAGGCAAATCCGAATCCATCCACGTGACCCTCAACGTAGAGCAGGCCTGTTACACCCGGGATGCG CTCGCCAAGGCCCTGCACGCCCGGGTCTTTGATTTCTTGGTAGATTCCATCAATAAAGCCATGGAGAAAGACCATGAAGAATACAACATT GGCGTCCTAGACATCTATGGCTTTGAAATATTCCAGAAAAATGGCTTTGAACAGTTTTGTATCAATTTTGTTAATGAAAAACTGCAGCAG ATTTTTATTGAACTGACATTAAAGGCAGAACAGGAAGAATATGTTCAAGAGGGAATAAGATGGACACCCATTGAGTACTTTAATAATAAA ATCGTATGTGACCTCATAGAGAACAAAGTGAACCCTCCTGGCATCATGAGCATCCTGGATGACGTGTGCGCCACGATGCATGCGGTGGGT GAGGGGGCAGATCAGACGCTGCTCCAGAAACTTCAGATGCAGATTGGGAGTCATGAGCACTTCAACAGTTGGAACCAAGGCTTCATCATT CATCATTATGCTGGGAAGGTATCCTATGACATGGATGGCTTTTGTGAAAGGAACCGGGATGTGCTTTTTATGGATCTCATCGAGCTTATG CAGAGCAGCGAGCTGCCTTTCATAAAGTCTTTATTTCCGGAAAATCTGCAGGCTGACAAGAAAGGGCGCCCAACTACTGCCGGAAGCAAA ATAAAGAAACAAGCCAATGACCTTGTGAGCACCCTGATGAAATGTACGCCCCACTACATTCGCTGCATCAAGCCAAACGAAACCAAGAAG CCCAGAGACTGGGAGGAAAGCAGGGTAAAGCATCAAGTCGAATATTTGGGTCTGAAAGAGAACATTCGAGTGAGAAGAGCTGGCTATGCC TATCGGCGCATCTTCCAAAAATTCCTACAGAGGTATGCCATTCTGACCAAAGCCACCTGGCCTTCTTGGCAGGGAGAGGAGAAGCAAGGC GTCCTGCACCTGCTGCAGTCGGTCAACATGGACAGCGACCAGTTCCAGCTGGGGAGGAGTAAAGTGTTCATCAAAGCCCCCGAGTCTCTA TTTCTTTTAGAAGAGATGAGAGAGAGAAAGTATGATGGGTATGCTCGAGTGATACAGAAATCATGGAGGAAATTCGTGGCCCGGAAGAAA TACGTTCAAATGAGAGAAGAAGCCTCAGACCTCTTATTGAACAAGAAGGAGAGAAGGAGAAACAGTATTAACAGGAACTTTATAGGGGAT TATATTGGGATGGAAGAGCACCCAGAACTCCAGCAGTTCGTGGGCAAGAGGGAGAAGATTGATTTCGCAGACACAGTCACCAAGTATGAC AGGAGGTTCAAGGGTGTAAAGCGAGACCTGCTCCTTACCCCAAAGTGCTTGTACTTAATCGGACGAGAAAAAGTCAAACAGGGCCCAGAC AAGGGCCTGGTGAAAGAAGTCCTGAAGCGGAAAATCGAGATAGAACGGATCTTGTCTGTGTCCCTCAGTACTATGCAGGATGACATTTTT ATTCTCCATGAGCAAGAGTATGACAGTTTGCTTGAATCTGTCTTCAAAACTGAATTCCTAAGCCTCTTAGCAAAGCGTTACGAGGAGAAG ACCCAGAAGCAACTACCTCTGAAATTCAGCAATACGCTTGAACTGAAGTTGAAAAAGGAAAACTGGGGCCCCTGGAGTGCAGGGGGCTCC CGGCAAGTGCAGTTCCACCAAGGGTTTGGGGACCTGGCTGTCCTCAAGCCCAGTAACAAAGTGCTGCAGGTCAGCATCGGACCTGGACTG CCCAAGAACTCCCGTCCTACCAGAAGGAACACTACCCAAAATACAGGTTATTCCAGTGGGACTCAAAATGCCAACTACCCAGTGAGAGCT GCCCCTCCTCCCCCAGGATACCATCAGAACGGAGTCATCAGAAACCAGTATGTGCCATATCCCCATGCTCCTGGAAGCCAGAGGTCCAAT CAGAAAAGCCTGTACACCTCCATGGCCCGCCCGCCCTTGCCTCGGCAGCAGTCTACCAGTTCAGACCGAGTGTCACAGACGCCAGAGAGC CTGGATTTCCTCAAGGTCCCGGACCAGGGAGCTGCAGGGGTCAGGAGACAAACAACCAGTCGGCCTCCCCCAGCAGGGGGCAGACCCAAG CCCCAGCCCAAGCCCAAGCCTCAGGTGCCACAGTGCAAGGCTTTGTATGCCTATGACGCTCAGGACACAGACGAACTCAGCTTTAATGCC AATGACATTATTGATATTATCAAAGAAGATCCTTCTGGCTGGTGGACGGGTCGACTACGAGGCAAGCAGGGCCTGTTCCCCAACAACTAT GTGACCAAGATCTGAGGTGCCCGTGACTCTGACACATGGGGCAGAGGAGCTCCAGGCACAGACCAGGGGAGGGGATATTTAGGGGCTCCC CTTACAATCCACAATGAGCAATTGCTTCTCCAAGGCCTGGAGCTATTCTGGTACCTTCCCCATGGAGGACACTGAAAAGGCTGGGTTGGG GACAGGGAGTATCACTCCATAAGTGATCCTAAAAGGTAGCCTCTTCATAGGAACCCAGGAGGACAAAACCACCATGCATTAAGATTTATT TATTGTATTTAAACCTGGTGAGAGGACAAGTGAGGTCTGCTCAGACCTTGTAGGCTTCTATCAAAACAGCACCCTGCTTGCTCACCAGGC CTAGAGAATGGCTGTAGGTGGCCGCTGACAAGTGCCTTTAGTTGAAGAGCACATTTCTTTCATCTCTCTTGTCCATACCTGATAGACACA TTCCTCTCTGCCACCTTCCTTCAGGGAGGACCCGCCCTCTGCAGACTGGGCTTAGCGTGAGCAGGCACTTCCCATGTACGTGCCAAGGGT AAGCTGGCCTGCTGAGCCCAGGGCGACAGAGGGGCACTGGTTTACACTTTGCCGGGACCATCAGGGCCGCCAAGCAGGTCAGGGGCTGGG GGCTGGGGGCTGGGCTGCTGGCTTTGCTTTCTCTGGGTCTTCAATTAGAATGTGGCTGGCCCATATTGGTTTGTGTTTAAATGCTGTACT TACTACAAGAAGGATCTTTTTTCAAGCTGTACATTTATAAAAACAGATCATATACTGTATATATAAAAATCTTGAGATGGTAGAAACATG TATGAATGTACTAAGTAGTATTCCACTGTACTCATTCATAAGGTAGGTTTTCTTACAAAACTCACACCAGGTACTTAAAGATGTGCTCTG CTTTTTTCCAACTACGGAGTGTCACTGCTTTCTAGGTCAGTCCCTGCAGACTCTTCTCAACTCTTTCCCTATAGGAAACTTACTCCGCGT CCTGCCCCCACCTCCTAAATAAATAAAGGAATCGGCGAACACCTTCTTCTTTTATGACATTTGTTATGGGTTGAATTGTGTGCCTCCAAA GAAGATGTTGGAGTCCCAGCCACCAGTACCTCACAATATGACCTTATTTGGAAATAGAGTCTTTATGGAGCAAACAAACAAAACTAATTA AAATGAAGTCATTAGAGTGGGTCTTAATCCAATATAATGGTGTCCTGATGAAAAGGGGAAATTTGGACACAGAGACCAACATGCCAGAGG AAAGACCATGTGAAAAGGCAGGGAGAAGACAGCCATTCACAAGCCCTGGACAGAGGCCTGGAACAGATTCTCCCTCACACCCTCACAAGG AACCAGCCCTGCCCACCTTGGTCTTGGACTTCCAACCTCCAGAACTGTGAGGCAATACATTTCGCTGTTTAAGCCACTCGGTTTGTGGTA GTTTGTTACGGCAGCCCTAACAAACTAAAACAATGTTTTCTTGCCATAATAGTGAAAAGCTGGAATCAGTGTAATGCCCATCAATAATGG AATGGTTGTAAGTAGAGACTGCCATTTCTCTACCTTTCCTCCTCTGGGTGCCATAGCCATTCTTAAGCTACTGGTAACTTAGAGTTTGAG CAGCATACACCTTTGAGGCTTTCAGGATCCTCAAGTCCATGGGAAAAAATTATCAGGGCTTACGTATAAGGGAAAAAAATTGATCTAGAT TTGAAACGAAGATACATTTAATTCTGCTGTGTTTTACTTCAAGAACAGGGAGCAAACTCCATTCTGTAACAGTAACGAATAATGTTAAAA GGCTACTTCAGTTCCATGTTGCGACCAGAGAGGAAAGTAGAGCCATGATGCGGTGAGTTGAGGAAAGGTAATCCTGTTGACACTAGTGGT CTCTAAAGTACTTTCACATTCATGGACTCCCCGCAGTGGGAGGAAGATACCACCAGAACTGGGACAGAGGAGCATGCTGGAGTCCCCACA GCCACCAGCACTCAGGCTGCGTTCTCAGGGCAGGAACACCAGGACCATCTTCCCTTGTTATCATAAGCCCCTGGCTGGCTGGGACAAGCC TTTGTTTTTCCTCCTGATTGATTGATTGGCATTTTACACTTGTGTGTAACTGGGAACCATCGGGCTCTAGGTCACAAAACAGGGACTGAG TTAAACCCCCACGAGTAACACCCTCATCCATGGAAATCACAGACCAAGCCCTTAGCACCTGCATCGTGTGCCCAGCCAGTGCCAGGCTCA AGGAGATGCCCAACAAATGGTGCTGAAATAGGTAAGTGACCCACAGGGGAAGGAGACTTAGATCTGCGTAGAGATGCTGAAATGCTGACA CTATTAAGAAAAGTTTGGAGAAATAGTGGTTTATCTTAAACTTATTTGTATATATTTAGAAATTCAACATGGGGACTACCAGAAAAATCT >56960_56960_1_NAA20-MYO1E_NAA20_chr20_20003124_ENST00000310450_MYO1E_chr15_59553708_ENST00000288235_length(amino acids)=1085AA_BP=26 MTTLRAFTCDDLFRFNNINLDPLTETTYIGSVLISVNPFKQMPYFGEKEIEMYQGAAQYENPPHIYALADNMYRNMIIDRENQCVIISGE SGAGKTVAAKYIMSYISRVSGGGTKVQHVKDIILQSNPLLEAFGNAKTVRNNNSSRFGKYFEIQFSPGGEPDGGKISNFLLEKSRVVMRN PGERSFHIFYQLIEGASAEQKHSLGITSMDYYYYLSLSGSYKVDDIDDRREFQETLHAMNVIGIFAEEQTLVLQIVAGILHLGNISFKEV GNYAAVESEEFLAFPAYLLGINQDRLKEKLTSRQMDSKWGGKSESIHVTLNVEQACYTRDALAKALHARVFDFLVDSINKAMEKDHEEYN IGVLDIYGFEIFQKNGFEQFCINFVNEKLQQIFIELTLKAEQEEYVQEGIRWTPIEYFNNKIVCDLIENKVNPPGIMSILDDVCATMHAV GEGADQTLLQKLQMQIGSHEHFNSWNQGFIIHHYAGKVSYDMDGFCERNRDVLFMDLIELMQSSELPFIKSLFPENLQADKKGRPTTAGS KIKKQANDLVSTLMKCTPHYIRCIKPNETKKPRDWEESRVKHQVEYLGLKENIRVRRAGYAYRRIFQKFLQRYAILTKATWPSWQGEEKQ GVLHLLQSVNMDSDQFQLGRSKVFIKAPESLFLLEEMRERKYDGYARVIQKSWRKFVARKKYVQMREEASDLLLNKKERRRNSINRNFIG DYIGMEEHPELQQFVGKREKIDFADTVTKYDRRFKGVKRDLLLTPKCLYLIGREKVKQGPDKGLVKEVLKRKIEIERILSVSLSTMQDDI FILHEQEYDSLLESVFKTEFLSLLAKRYEEKTQKQLPLKFSNTLELKLKKENWGPWSAGGSRQVQFHQGFGDLAVLKPSNKVLQVSIGPG LPKNSRPTRRNTTQNTGYSSGTQNANYPVRAAPPPPGYHQNGVIRNQYVPYPHAPGSQRSNQKSLYTSMARPPLPRQQSTSSDRVSQTPE SLDFLKVPDQGAAGVRRQTTSRPPPAGGRPKPQPKPKPQVPQCKALYAYDAQDTDELSFNANDIIDIIKEDPSGWWTGRLRGKQGLFPNN -------------------------------------------------------------- >56960_56960_2_NAA20-MYO1E_NAA20_chr20_20003124_ENST00000334982_MYO1E_chr15_59553708_ENST00000288235_length(transcript)=6005nt_BP=359nt TTTCCTTCCCAGGTGTCGCCGCCTGCTTTCTGCAGCCGCTGCCTGGGAGGGGTTCCGAGGTTCTGGGCAGCCACAGCCCCGGAGGCCTTA CAGGAGCGACCTGGCAATTCCCGCCGCCGGCCGCCAGAGGAAGCTGCTTTGCTGCTGTCGTTGCCCAGCAACTCGTAGCCCGGAAGCAGT ACCCCGTCTCGCTCGGTTCCGCGGCGGCCACGCTCCGGGAGACTTCCGGCAGGGCGGGCGCGGGGTCTTGGCGAACGGTCTTCGGAAGCG GCGGCGGCGCGATGACCACGCTACGGGCCTTTACCTGCGACGACCTGTTCCGCTTCAACAACATTAACTTGGATCCACTTACAGAAACTA CATATATAGGATCTGTATTAATCTCAGTCAACCCTTTCAAGCAGATGCCATATTTTGGGGAAAAGGAAATTGAAATGTACCAAGGAGCGG CACAGTATGAAAACCCACCACATATCTATGCCCTTGCAGATAATATGTACAGAAACATGATCATTGACAGAGAGAACCAGTGCGTCATTA TCAGTGGTGAAAGTGGTGCTGGAAAAACAGTGGCTGCCAAATATATCATGAGCTACATCTCCAGAGTGTCTGGAGGAGGGACCAAAGTCC AGCACGTGAAGGACATTATCCTGCAGTCCAACCCGCTGCTGGAGGCCTTCGGGAACGCCAAGACCGTCCGGAACAACAACTCCAGCCGAT TTGGAAAATACTTTGAAATCCAGTTCAGTCCAGGTGGGGAACCAGATGGTGGAAAGATCTCCAACTTCCTTCTGGAAAAATCTAGGGTGG TGATGAGGAACCCAGGAGAGCGGAGTTTTCACATATTTTACCAGCTCATCGAGGGCGCCTCTGCAGAGCAGAAACACAGCCTTGGCATCA CCAGCATGGACTATTATTACTACCTGAGCCTCTCGGGCTCATACAAGGTTGATGACATTGACGACAGGCGGGAGTTTCAGGAAACTCTGC ACGCCATGAATGTGATTGGGATCTTTGCAGAAGAGCAAACGCTGGTGTTGCAGATAGTGGCGGGTATTCTCCACCTGGGAAACATCAGCT TCAAAGAAGTTGGCAACTACGCGGCTGTGGAGAGTGAAGAGTTTTTAGCTTTTCCTGCATATCTGCTAGGGATAAACCAGGACCGGTTGA AAGAAAAGCTAACAAGCCGGCAGATGGATAGCAAGTGGGGAGGCAAATCCGAATCCATCCACGTGACCCTCAACGTAGAGCAGGCCTGTT ACACCCGGGATGCGCTCGCCAAGGCCCTGCACGCCCGGGTCTTTGATTTCTTGGTAGATTCCATCAATAAAGCCATGGAGAAAGACCATG AAGAATACAACATTGGCGTCCTAGACATCTATGGCTTTGAAATATTCCAGAAAAATGGCTTTGAACAGTTTTGTATCAATTTTGTTAATG AAAAACTGCAGCAGATTTTTATTGAACTGACATTAAAGGCAGAACAGGAAGAATATGTTCAAGAGGGAATAAGATGGACACCCATTGAGT ACTTTAATAATAAAATCGTATGTGACCTCATAGAGAACAAAGTGAACCCTCCTGGCATCATGAGCATCCTGGATGACGTGTGCGCCACGA TGCATGCGGTGGGTGAGGGGGCAGATCAGACGCTGCTCCAGAAACTTCAGATGCAGATTGGGAGTCATGAGCACTTCAACAGTTGGAACC AAGGCTTCATCATTCATCATTATGCTGGGAAGGTATCCTATGACATGGATGGCTTTTGTGAAAGGAACCGGGATGTGCTTTTTATGGATC TCATCGAGCTTATGCAGAGCAGCGAGCTGCCTTTCATAAAGTCTTTATTTCCGGAAAATCTGCAGGCTGACAAGAAAGGGCGCCCAACTA CTGCCGGAAGCAAAATAAAGAAACAAGCCAATGACCTTGTGAGCACCCTGATGAAATGTACGCCCCACTACATTCGCTGCATCAAGCCAA ACGAAACCAAGAAGCCCAGAGACTGGGAGGAAAGCAGGGTAAAGCATCAAGTCGAATATTTGGGTCTGAAAGAGAACATTCGAGTGAGAA GAGCTGGCTATGCCTATCGGCGCATCTTCCAAAAATTCCTACAGAGGTATGCCATTCTGACCAAAGCCACCTGGCCTTCTTGGCAGGGAG AGGAGAAGCAAGGCGTCCTGCACCTGCTGCAGTCGGTCAACATGGACAGCGACCAGTTCCAGCTGGGGAGGAGTAAAGTGTTCATCAAAG CCCCCGAGTCTCTATTTCTTTTAGAAGAGATGAGAGAGAGAAAGTATGATGGGTATGCTCGAGTGATACAGAAATCATGGAGGAAATTCG TGGCCCGGAAGAAATACGTTCAAATGAGAGAAGAAGCCTCAGACCTCTTATTGAACAAGAAGGAGAGAAGGAGAAACAGTATTAACAGGA ACTTTATAGGGGATTATATTGGGATGGAAGAGCACCCAGAACTCCAGCAGTTCGTGGGCAAGAGGGAGAAGATTGATTTCGCAGACACAG TCACCAAGTATGACAGGAGGTTCAAGGGTGTAAAGCGAGACCTGCTCCTTACCCCAAAGTGCTTGTACTTAATCGGACGAGAAAAAGTCA AACAGGGCCCAGACAAGGGCCTGGTGAAAGAAGTCCTGAAGCGGAAAATCGAGATAGAACGGATCTTGTCTGTGTCCCTCAGTACTATGC AGGATGACATTTTTATTCTCCATGAGCAAGAGTATGACAGTTTGCTTGAATCTGTCTTCAAAACTGAATTCCTAAGCCTCTTAGCAAAGC GTTACGAGGAGAAGACCCAGAAGCAACTACCTCTGAAATTCAGCAATACGCTTGAACTGAAGTTGAAAAAGGAAAACTGGGGCCCCTGGA GTGCAGGGGGCTCCCGGCAAGTGCAGTTCCACCAAGGGTTTGGGGACCTGGCTGTCCTCAAGCCCAGTAACAAAGTGCTGCAGGTCAGCA TCGGACCTGGACTGCCCAAGAACTCCCGTCCTACCAGAAGGAACACTACCCAAAATACAGGTTATTCCAGTGGGACTCAAAATGCCAACT ACCCAGTGAGAGCTGCCCCTCCTCCCCCAGGATACCATCAGAACGGAGTCATCAGAAACCAGTATGTGCCATATCCCCATGCTCCTGGAA GCCAGAGGTCCAATCAGAAAAGCCTGTACACCTCCATGGCCCGCCCGCCCTTGCCTCGGCAGCAGTCTACCAGTTCAGACCGAGTGTCAC AGACGCCAGAGAGCCTGGATTTCCTCAAGGTCCCGGACCAGGGAGCTGCAGGGGTCAGGAGACAAACAACCAGTCGGCCTCCCCCAGCAG GGGGCAGACCCAAGCCCCAGCCCAAGCCCAAGCCTCAGGTGCCACAGTGCAAGGCTTTGTATGCCTATGACGCTCAGGACACAGACGAAC TCAGCTTTAATGCCAATGACATTATTGATATTATCAAAGAAGATCCTTCTGGCTGGTGGACGGGTCGACTACGAGGCAAGCAGGGCCTGT TCCCCAACAACTATGTGACCAAGATCTGAGGTGCCCGTGACTCTGACACATGGGGCAGAGGAGCTCCAGGCACAGACCAGGGGAGGGGAT ATTTAGGGGCTCCCCTTACAATCCACAATGAGCAATTGCTTCTCCAAGGCCTGGAGCTATTCTGGTACCTTCCCCATGGAGGACACTGAA AAGGCTGGGTTGGGGACAGGGAGTATCACTCCATAAGTGATCCTAAAAGGTAGCCTCTTCATAGGAACCCAGGAGGACAAAACCACCATG CATTAAGATTTATTTATTGTATTTAAACCTGGTGAGAGGACAAGTGAGGTCTGCTCAGACCTTGTAGGCTTCTATCAAAACAGCACCCTG CTTGCTCACCAGGCCTAGAGAATGGCTGTAGGTGGCCGCTGACAAGTGCCTTTAGTTGAAGAGCACATTTCTTTCATCTCTCTTGTCCAT ACCTGATAGACACATTCCTCTCTGCCACCTTCCTTCAGGGAGGACCCGCCCTCTGCAGACTGGGCTTAGCGTGAGCAGGCACTTCCCATG TACGTGCCAAGGGTAAGCTGGCCTGCTGAGCCCAGGGCGACAGAGGGGCACTGGTTTACACTTTGCCGGGACCATCAGGGCCGCCAAGCA GGTCAGGGGCTGGGGGCTGGGGGCTGGGCTGCTGGCTTTGCTTTCTCTGGGTCTTCAATTAGAATGTGGCTGGCCCATATTGGTTTGTGT TTAAATGCTGTACTTACTACAAGAAGGATCTTTTTTCAAGCTGTACATTTATAAAAACAGATCATATACTGTATATATAAAAATCTTGAG ATGGTAGAAACATGTATGAATGTACTAAGTAGTATTCCACTGTACTCATTCATAAGGTAGGTTTTCTTACAAAACTCACACCAGGTACTT AAAGATGTGCTCTGCTTTTTTCCAACTACGGAGTGTCACTGCTTTCTAGGTCAGTCCCTGCAGACTCTTCTCAACTCTTTCCCTATAGGA AACTTACTCCGCGTCCTGCCCCCACCTCCTAAATAAATAAAGGAATCGGCGAACACCTTCTTCTTTTATGACATTTGTTATGGGTTGAAT TGTGTGCCTCCAAAGAAGATGTTGGAGTCCCAGCCACCAGTACCTCACAATATGACCTTATTTGGAAATAGAGTCTTTATGGAGCAAACA AACAAAACTAATTAAAATGAAGTCATTAGAGTGGGTCTTAATCCAATATAATGGTGTCCTGATGAAAAGGGGAAATTTGGACACAGAGAC CAACATGCCAGAGGAAAGACCATGTGAAAAGGCAGGGAGAAGACAGCCATTCACAAGCCCTGGACAGAGGCCTGGAACAGATTCTCCCTC ACACCCTCACAAGGAACCAGCCCTGCCCACCTTGGTCTTGGACTTCCAACCTCCAGAACTGTGAGGCAATACATTTCGCTGTTTAAGCCA CTCGGTTTGTGGTAGTTTGTTACGGCAGCCCTAACAAACTAAAACAATGTTTTCTTGCCATAATAGTGAAAAGCTGGAATCAGTGTAATG CCCATCAATAATGGAATGGTTGTAAGTAGAGACTGCCATTTCTCTACCTTTCCTCCTCTGGGTGCCATAGCCATTCTTAAGCTACTGGTA ACTTAGAGTTTGAGCAGCATACACCTTTGAGGCTTTCAGGATCCTCAAGTCCATGGGAAAAAATTATCAGGGCTTACGTATAAGGGAAAA AAATTGATCTAGATTTGAAACGAAGATACATTTAATTCTGCTGTGTTTTACTTCAAGAACAGGGAGCAAACTCCATTCTGTAACAGTAAC GAATAATGTTAAAAGGCTACTTCAGTTCCATGTTGCGACCAGAGAGGAAAGTAGAGCCATGATGCGGTGAGTTGAGGAAAGGTAATCCTG TTGACACTAGTGGTCTCTAAAGTACTTTCACATTCATGGACTCCCCGCAGTGGGAGGAAGATACCACCAGAACTGGGACAGAGGAGCATG CTGGAGTCCCCACAGCCACCAGCACTCAGGCTGCGTTCTCAGGGCAGGAACACCAGGACCATCTTCCCTTGTTATCATAAGCCCCTGGCT GGCTGGGACAAGCCTTTGTTTTTCCTCCTGATTGATTGATTGGCATTTTACACTTGTGTGTAACTGGGAACCATCGGGCTCTAGGTCACA AAACAGGGACTGAGTTAAACCCCCACGAGTAACACCCTCATCCATGGAAATCACAGACCAAGCCCTTAGCACCTGCATCGTGTGCCCAGC CAGTGCCAGGCTCAAGGAGATGCCCAACAAATGGTGCTGAAATAGGTAAGTGACCCACAGGGGAAGGAGACTTAGATCTGCGTAGAGATG CTGAAATGCTGACACTATTAAGAAAAGTTTGGAGAAATAGTGGTTTATCTTAAACTTATTTGTATATATTTAGAAATTCAACATGGGGAC >56960_56960_2_NAA20-MYO1E_NAA20_chr20_20003124_ENST00000334982_MYO1E_chr15_59553708_ENST00000288235_length(amino acids)=1169AA_BP=110 MQPLPGRGSEVLGSHSPGGLTGATWQFPPPAARGSCFAAVVAQQLVARKQYPVSLGSAAATLRETSGRAGAGSWRTVFGSGGGAMTTLRA FTCDDLFRFNNINLDPLTETTYIGSVLISVNPFKQMPYFGEKEIEMYQGAAQYENPPHIYALADNMYRNMIIDRENQCVIISGESGAGKT VAAKYIMSYISRVSGGGTKVQHVKDIILQSNPLLEAFGNAKTVRNNNSSRFGKYFEIQFSPGGEPDGGKISNFLLEKSRVVMRNPGERSF HIFYQLIEGASAEQKHSLGITSMDYYYYLSLSGSYKVDDIDDRREFQETLHAMNVIGIFAEEQTLVLQIVAGILHLGNISFKEVGNYAAV ESEEFLAFPAYLLGINQDRLKEKLTSRQMDSKWGGKSESIHVTLNVEQACYTRDALAKALHARVFDFLVDSINKAMEKDHEEYNIGVLDI YGFEIFQKNGFEQFCINFVNEKLQQIFIELTLKAEQEEYVQEGIRWTPIEYFNNKIVCDLIENKVNPPGIMSILDDVCATMHAVGEGADQ TLLQKLQMQIGSHEHFNSWNQGFIIHHYAGKVSYDMDGFCERNRDVLFMDLIELMQSSELPFIKSLFPENLQADKKGRPTTAGSKIKKQA NDLVSTLMKCTPHYIRCIKPNETKKPRDWEESRVKHQVEYLGLKENIRVRRAGYAYRRIFQKFLQRYAILTKATWPSWQGEEKQGVLHLL QSVNMDSDQFQLGRSKVFIKAPESLFLLEEMRERKYDGYARVIQKSWRKFVARKKYVQMREEASDLLLNKKERRRNSINRNFIGDYIGME EHPELQQFVGKREKIDFADTVTKYDRRFKGVKRDLLLTPKCLYLIGREKVKQGPDKGLVKEVLKRKIEIERILSVSLSTMQDDIFILHEQ EYDSLLESVFKTEFLSLLAKRYEEKTQKQLPLKFSNTLELKLKKENWGPWSAGGSRQVQFHQGFGDLAVLKPSNKVLQVSIGPGLPKNSR PTRRNTTQNTGYSSGTQNANYPVRAAPPPPGYHQNGVIRNQYVPYPHAPGSQRSNQKSLYTSMARPPLPRQQSTSSDRVSQTPESLDFLK -------------------------------------------------------------- >56960_56960_3_NAA20-MYO1E_NAA20_chr20_20003124_ENST00000398602_MYO1E_chr15_59553708_ENST00000288235_length(transcript)=6323nt_BP=677nt CGGCGCGATGACCACGCTACGGGCCTTTACCTGCGACGACCTGTTCCGCTTCAACAACATGTGAGTGACACGCGCCTAGGGCCAGCCGCT CTTGGCCGGGCCTCGCTTCCCGGCCCCGCCAGCTCCGGCCCCAGCCGCGCCTTCCCGGCCGGACCCCAAGCCCGGACGGGGACCCGCGAG AACCACCCCCCGCCGGCCAACGTGGGCGCCTCCCTGGGGCCACAGGGTCCAGGGAGAGGTGGGCCTGGAGTCGACGCACGCCGGCCTTGG CGACCTTGGCCGAGGTGCTCAAACTTTGTCTCTGGACCCTGCGAGCTGGCAGGTTCTGGGGCAGCGCTCGGGCCTCCGCTCGTGGTCGCT GTCAGGAGGCGCTGGGGTGATGGGGCGAGCTGGAGACGCGGCCTGGAGCCCACGACCTGGGCTTCTCGCCCTGCCCTACTGCTTGCTGGT TCGTGGCCGGGCCGCGCCTCTTCTGGGCAGAGGGCACCGCCGACGGCCAGGCCGCAGAGGGGGCTTGCGAGGATCGGAAGCTGGTCAGCA GCTGTTGGGATGTGTACATCGTGAAGCCCACCTGGTGGCCGTGGTTAAATTGTATCCAAATGAAATGACACTGATCACTGCGTCCCCTGC AGCAGATGCTGTCTCAGTCATGTAACTTGGATCCACTTACAGAAACTACATATATAGGATCTGTATTAATCTCAGTCAACCCTTTCAAGC AGATGCCATATTTTGGGGAAAAGGAAATTGAAATGTACCAAGGAGCGGCACAGTATGAAAACCCACCACATATCTATGCCCTTGCAGATA ATATGTACAGAAACATGATCATTGACAGAGAGAACCAGTGCGTCATTATCAGTGGTGAAAGTGGTGCTGGAAAAACAGTGGCTGCCAAAT ATATCATGAGCTACATCTCCAGAGTGTCTGGAGGAGGGACCAAAGTCCAGCACGTGAAGGACATTATCCTGCAGTCCAACCCGCTGCTGG AGGCCTTCGGGAACGCCAAGACCGTCCGGAACAACAACTCCAGCCGATTTGGAAAATACTTTGAAATCCAGTTCAGTCCAGGTGGGGAAC CAGATGGTGGAAAGATCTCCAACTTCCTTCTGGAAAAATCTAGGGTGGTGATGAGGAACCCAGGAGAGCGGAGTTTTCACATATTTTACC AGCTCATCGAGGGCGCCTCTGCAGAGCAGAAACACAGCCTTGGCATCACCAGCATGGACTATTATTACTACCTGAGCCTCTCGGGCTCAT ACAAGGTTGATGACATTGACGACAGGCGGGAGTTTCAGGAAACTCTGCACGCCATGAATGTGATTGGGATCTTTGCAGAAGAGCAAACGC TGGTGTTGCAGATAGTGGCGGGTATTCTCCACCTGGGAAACATCAGCTTCAAAGAAGTTGGCAACTACGCGGCTGTGGAGAGTGAAGAGT TTTTAGCTTTTCCTGCATATCTGCTAGGGATAAACCAGGACCGGTTGAAAGAAAAGCTAACAAGCCGGCAGATGGATAGCAAGTGGGGAG GCAAATCCGAATCCATCCACGTGACCCTCAACGTAGAGCAGGCCTGTTACACCCGGGATGCGCTCGCCAAGGCCCTGCACGCCCGGGTCT TTGATTTCTTGGTAGATTCCATCAATAAAGCCATGGAGAAAGACCATGAAGAATACAACATTGGCGTCCTAGACATCTATGGCTTTGAAA TATTCCAGAAAAATGGCTTTGAACAGTTTTGTATCAATTTTGTTAATGAAAAACTGCAGCAGATTTTTATTGAACTGACATTAAAGGCAG AACAGGAAGAATATGTTCAAGAGGGAATAAGATGGACACCCATTGAGTACTTTAATAATAAAATCGTATGTGACCTCATAGAGAACAAAG TGAACCCTCCTGGCATCATGAGCATCCTGGATGACGTGTGCGCCACGATGCATGCGGTGGGTGAGGGGGCAGATCAGACGCTGCTCCAGA AACTTCAGATGCAGATTGGGAGTCATGAGCACTTCAACAGTTGGAACCAAGGCTTCATCATTCATCATTATGCTGGGAAGGTATCCTATG ACATGGATGGCTTTTGTGAAAGGAACCGGGATGTGCTTTTTATGGATCTCATCGAGCTTATGCAGAGCAGCGAGCTGCCTTTCATAAAGT CTTTATTTCCGGAAAATCTGCAGGCTGACAAGAAAGGGCGCCCAACTACTGCCGGAAGCAAAATAAAGAAACAAGCCAATGACCTTGTGA GCACCCTGATGAAATGTACGCCCCACTACATTCGCTGCATCAAGCCAAACGAAACCAAGAAGCCCAGAGACTGGGAGGAAAGCAGGGTAA AGCATCAAGTCGAATATTTGGGTCTGAAAGAGAACATTCGAGTGAGAAGAGCTGGCTATGCCTATCGGCGCATCTTCCAAAAATTCCTAC AGAGGTATGCCATTCTGACCAAAGCCACCTGGCCTTCTTGGCAGGGAGAGGAGAAGCAAGGCGTCCTGCACCTGCTGCAGTCGGTCAACA TGGACAGCGACCAGTTCCAGCTGGGGAGGAGTAAAGTGTTCATCAAAGCCCCCGAGTCTCTATTTCTTTTAGAAGAGATGAGAGAGAGAA AGTATGATGGGTATGCTCGAGTGATACAGAAATCATGGAGGAAATTCGTGGCCCGGAAGAAATACGTTCAAATGAGAGAAGAAGCCTCAG ACCTCTTATTGAACAAGAAGGAGAGAAGGAGAAACAGTATTAACAGGAACTTTATAGGGGATTATATTGGGATGGAAGAGCACCCAGAAC TCCAGCAGTTCGTGGGCAAGAGGGAGAAGATTGATTTCGCAGACACAGTCACCAAGTATGACAGGAGGTTCAAGGGTGTAAAGCGAGACC TGCTCCTTACCCCAAAGTGCTTGTACTTAATCGGACGAGAAAAAGTCAAACAGGGCCCAGACAAGGGCCTGGTGAAAGAAGTCCTGAAGC GGAAAATCGAGATAGAACGGATCTTGTCTGTGTCCCTCAGTACTATGCAGGATGACATTTTTATTCTCCATGAGCAAGAGTATGACAGTT TGCTTGAATCTGTCTTCAAAACTGAATTCCTAAGCCTCTTAGCAAAGCGTTACGAGGAGAAGACCCAGAAGCAACTACCTCTGAAATTCA GCAATACGCTTGAACTGAAGTTGAAAAAGGAAAACTGGGGCCCCTGGAGTGCAGGGGGCTCCCGGCAAGTGCAGTTCCACCAAGGGTTTG GGGACCTGGCTGTCCTCAAGCCCAGTAACAAAGTGCTGCAGGTCAGCATCGGACCTGGACTGCCCAAGAACTCCCGTCCTACCAGAAGGA ACACTACCCAAAATACAGGTTATTCCAGTGGGACTCAAAATGCCAACTACCCAGTGAGAGCTGCCCCTCCTCCCCCAGGATACCATCAGA ACGGAGTCATCAGAAACCAGTATGTGCCATATCCCCATGCTCCTGGAAGCCAGAGGTCCAATCAGAAAAGCCTGTACACCTCCATGGCCC GCCCGCCCTTGCCTCGGCAGCAGTCTACCAGTTCAGACCGAGTGTCACAGACGCCAGAGAGCCTGGATTTCCTCAAGGTCCCGGACCAGG GAGCTGCAGGGGTCAGGAGACAAACAACCAGTCGGCCTCCCCCAGCAGGGGGCAGACCCAAGCCCCAGCCCAAGCCCAAGCCTCAGGTGC CACAGTGCAAGGCTTTGTATGCCTATGACGCTCAGGACACAGACGAACTCAGCTTTAATGCCAATGACATTATTGATATTATCAAAGAAG ATCCTTCTGGCTGGTGGACGGGTCGACTACGAGGCAAGCAGGGCCTGTTCCCCAACAACTATGTGACCAAGATCTGAGGTGCCCGTGACT CTGACACATGGGGCAGAGGAGCTCCAGGCACAGACCAGGGGAGGGGATATTTAGGGGCTCCCCTTACAATCCACAATGAGCAATTGCTTC TCCAAGGCCTGGAGCTATTCTGGTACCTTCCCCATGGAGGACACTGAAAAGGCTGGGTTGGGGACAGGGAGTATCACTCCATAAGTGATC CTAAAAGGTAGCCTCTTCATAGGAACCCAGGAGGACAAAACCACCATGCATTAAGATTTATTTATTGTATTTAAACCTGGTGAGAGGACA AGTGAGGTCTGCTCAGACCTTGTAGGCTTCTATCAAAACAGCACCCTGCTTGCTCACCAGGCCTAGAGAATGGCTGTAGGTGGCCGCTGA CAAGTGCCTTTAGTTGAAGAGCACATTTCTTTCATCTCTCTTGTCCATACCTGATAGACACATTCCTCTCTGCCACCTTCCTTCAGGGAG GACCCGCCCTCTGCAGACTGGGCTTAGCGTGAGCAGGCACTTCCCATGTACGTGCCAAGGGTAAGCTGGCCTGCTGAGCCCAGGGCGACA GAGGGGCACTGGTTTACACTTTGCCGGGACCATCAGGGCCGCCAAGCAGGTCAGGGGCTGGGGGCTGGGGGCTGGGCTGCTGGCTTTGCT TTCTCTGGGTCTTCAATTAGAATGTGGCTGGCCCATATTGGTTTGTGTTTAAATGCTGTACTTACTACAAGAAGGATCTTTTTTCAAGCT GTACATTTATAAAAACAGATCATATACTGTATATATAAAAATCTTGAGATGGTAGAAACATGTATGAATGTACTAAGTAGTATTCCACTG TACTCATTCATAAGGTAGGTTTTCTTACAAAACTCACACCAGGTACTTAAAGATGTGCTCTGCTTTTTTCCAACTACGGAGTGTCACTGC TTTCTAGGTCAGTCCCTGCAGACTCTTCTCAACTCTTTCCCTATAGGAAACTTACTCCGCGTCCTGCCCCCACCTCCTAAATAAATAAAG GAATCGGCGAACACCTTCTTCTTTTATGACATTTGTTATGGGTTGAATTGTGTGCCTCCAAAGAAGATGTTGGAGTCCCAGCCACCAGTA CCTCACAATATGACCTTATTTGGAAATAGAGTCTTTATGGAGCAAACAAACAAAACTAATTAAAATGAAGTCATTAGAGTGGGTCTTAAT CCAATATAATGGTGTCCTGATGAAAAGGGGAAATTTGGACACAGAGACCAACATGCCAGAGGAAAGACCATGTGAAAAGGCAGGGAGAAG ACAGCCATTCACAAGCCCTGGACAGAGGCCTGGAACAGATTCTCCCTCACACCCTCACAAGGAACCAGCCCTGCCCACCTTGGTCTTGGA CTTCCAACCTCCAGAACTGTGAGGCAATACATTTCGCTGTTTAAGCCACTCGGTTTGTGGTAGTTTGTTACGGCAGCCCTAACAAACTAA AACAATGTTTTCTTGCCATAATAGTGAAAAGCTGGAATCAGTGTAATGCCCATCAATAATGGAATGGTTGTAAGTAGAGACTGCCATTTC TCTACCTTTCCTCCTCTGGGTGCCATAGCCATTCTTAAGCTACTGGTAACTTAGAGTTTGAGCAGCATACACCTTTGAGGCTTTCAGGAT CCTCAAGTCCATGGGAAAAAATTATCAGGGCTTACGTATAAGGGAAAAAAATTGATCTAGATTTGAAACGAAGATACATTTAATTCTGCT GTGTTTTACTTCAAGAACAGGGAGCAAACTCCATTCTGTAACAGTAACGAATAATGTTAAAAGGCTACTTCAGTTCCATGTTGCGACCAG AGAGGAAAGTAGAGCCATGATGCGGTGAGTTGAGGAAAGGTAATCCTGTTGACACTAGTGGTCTCTAAAGTACTTTCACATTCATGGACT CCCCGCAGTGGGAGGAAGATACCACCAGAACTGGGACAGAGGAGCATGCTGGAGTCCCCACAGCCACCAGCACTCAGGCTGCGTTCTCAG GGCAGGAACACCAGGACCATCTTCCCTTGTTATCATAAGCCCCTGGCTGGCTGGGACAAGCCTTTGTTTTTCCTCCTGATTGATTGATTG GCATTTTACACTTGTGTGTAACTGGGAACCATCGGGCTCTAGGTCACAAAACAGGGACTGAGTTAAACCCCCACGAGTAACACCCTCATC CATGGAAATCACAGACCAAGCCCTTAGCACCTGCATCGTGTGCCCAGCCAGTGCCAGGCTCAAGGAGATGCCCAACAAATGGTGCTGAAA TAGGTAAGTGACCCACAGGGGAAGGAGACTTAGATCTGCGTAGAGATGCTGAAATGCTGACACTATTAAGAAAAGTTTGGAGAAATAGTG GTTTATCTTAAACTTATTTGTATATATTTAGAAATTCAACATGGGGACTACCAGAAAAATCTGGGATAAATAACATTTCCCTTTTTTTCC >56960_56960_3_NAA20-MYO1E_NAA20_chr20_20003124_ENST00000398602_MYO1E_chr15_59553708_ENST00000288235_length(amino acids)=1079AA_BP=20 MRPLQQMLSQSCNLDPLTETTYIGSVLISVNPFKQMPYFGEKEIEMYQGAAQYENPPHIYALADNMYRNMIIDRENQCVIISGESGAGKT VAAKYIMSYISRVSGGGTKVQHVKDIILQSNPLLEAFGNAKTVRNNNSSRFGKYFEIQFSPGGEPDGGKISNFLLEKSRVVMRNPGERSF HIFYQLIEGASAEQKHSLGITSMDYYYYLSLSGSYKVDDIDDRREFQETLHAMNVIGIFAEEQTLVLQIVAGILHLGNISFKEVGNYAAV ESEEFLAFPAYLLGINQDRLKEKLTSRQMDSKWGGKSESIHVTLNVEQACYTRDALAKALHARVFDFLVDSINKAMEKDHEEYNIGVLDI YGFEIFQKNGFEQFCINFVNEKLQQIFIELTLKAEQEEYVQEGIRWTPIEYFNNKIVCDLIENKVNPPGIMSILDDVCATMHAVGEGADQ TLLQKLQMQIGSHEHFNSWNQGFIIHHYAGKVSYDMDGFCERNRDVLFMDLIELMQSSELPFIKSLFPENLQADKKGRPTTAGSKIKKQA NDLVSTLMKCTPHYIRCIKPNETKKPRDWEESRVKHQVEYLGLKENIRVRRAGYAYRRIFQKFLQRYAILTKATWPSWQGEEKQGVLHLL QSVNMDSDQFQLGRSKVFIKAPESLFLLEEMRERKYDGYARVIQKSWRKFVARKKYVQMREEASDLLLNKKERRRNSINRNFIGDYIGME EHPELQQFVGKREKIDFADTVTKYDRRFKGVKRDLLLTPKCLYLIGREKVKQGPDKGLVKEVLKRKIEIERILSVSLSTMQDDIFILHEQ EYDSLLESVFKTEFLSLLAKRYEEKTQKQLPLKFSNTLELKLKKENWGPWSAGGSRQVQFHQGFGDLAVLKPSNKVLQVSIGPGLPKNSR PTRRNTTQNTGYSSGTQNANYPVRAAPPPPGYHQNGVIRNQYVPYPHAPGSQRSNQKSLYTSMARPPLPRQQSTSSDRVSQTPESLDFLK -------------------------------------------------------------- |
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Fusion Gene PPI Analysis for NAA20-MYO1E |
| Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in |
| Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160) |
| Hgene | Hgene's interactors | Tgene | Tgene's interactors |
| - Retained PPIs in in-frame fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Still interaction with |
| - Lost PPIs in in-frame fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Interaction lost with |
| - Retained PPIs, but lost function due to frame-shift fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Interaction lost with |
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Related Drugs for NAA20-MYO1E |
| Drugs targeting genes involved in this fusion gene. (DrugBank Version 5.1.8 2021-05-08) |
| Partner | Gene | UniProtAcc | DrugBank ID | Drug name | Drug activity | Drug type | Drug status |
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Related Diseases for NAA20-MYO1E |
| Diseases associated with fusion partners. (DisGeNet 4.0) |
| Partner | Gene | Disease ID | Disease name | # pubmeds | Source |
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