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Center for Computational Systems Medicine
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Fusion Gene Summary

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Fusion Gene ORF analysis

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Fusion Genomic Features

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Fusion Protein Features

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Fusion Gene Sequence

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Fusion Gene PPI analysis

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Related Drugs

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Related Diseases

Fusion gene:NAALADL2-ABCC5 (FusionGDB2 ID:57022)

Fusion Gene Summary for NAALADL2-ABCC5

check button Fusion gene summary
Fusion gene informationFusion gene name: NAALADL2-ABCC5
Fusion gene ID: 57022
HgeneTgene
Gene symbol

NAALADL2

ABCC5

Gene ID

254827

10057

Gene nameN-acetylated alpha-linked acidic dipeptidase like 2ATP binding cassette subfamily C member 5
Synonyms-ABC33|EST277145|MOAT-C|MOATC|MRP5|SMRP|pABC11
Cytomap

3q26.31

3q27.1

Type of geneprotein-codingprotein-coding
Descriptioninactive N-acetylated-alpha-linked acidic dipeptidase-like protein 2N-acetylated alpha-linked acidic dipeptidase 2NAALADase L2glutamate carboxypeptidase II-type non-peptidase homologuemultidrug resistance-associated protein 5ATP-binding cassette, sub-family C (CFTR/MRP), member 5canalicular multispecific organic anion transporter Cmulti-specific organic anion transporter C
Modification date2020031320200313
UniProtAcc.

O15440

Ensembl transtripts involved in fusion geneENST00000454872, ENST00000473253, 
ENST00000382494, ENST00000392579, 
ENST00000427120, ENST00000446941, 
ENST00000492216, ENST00000265586, 
ENST00000334444, 
Fusion gene scores* DoF score28 X 19 X 9=47886 X 7 X 6=252
# samples 299
** MAII scorelog2(29/4788*10)=-4.04529834692857
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0		log2(9/252*10)=-1.48542682717024
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0
Context

PubMed: NAALADL2 [Title/Abstract] AND ABCC5 [Title/Abstract] AND fusion [Title/Abstract]

Most frequent breakpointNAALADL2(175345174)-ABCC5(183643507), # samples:4
ABCC5(183732052)-NAALADL2(174814580), # samples:1
Anticipated loss of major functional domain due to fusion event.ABCC5-NAALADL2 seems lost the major protein functional domain in Hgene partner, which is a cell metabolism gene due to the frame-shifted ORF.
ABCC5-NAALADL2 seems lost the major protein functional domain in Hgene partner, which is a IUPHAR drug target due to the frame-shifted ORF.
* DoF score (Degree of Frequency) = # partners X # break points X # cancer types
** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)

check button Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez
PartnerGeneGO IDGO termPubMed ID
TgeneABCC5

GO:0042908

xenobiotic transport

10840050

TgeneABCC5

GO:0140115

export across plasma membrane

10840050


check buttonFusion gene breakpoints across NAALADL2 (5'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check buttonFusion gene breakpoints across ABCC5 (3'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check button Fusion gene information from two resources (ChiTars 5.0 and ChimerDB 4.0)
* All genome coordinats were lifted-over on hg19.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
SourceDiseaseSampleHgeneHchrHbpHstrandTgeneTchrTbpTstrand
ChimerDB4LUSCTCGA-33-4538-01ANAALADL2chr3

175345173

+ABCC5chr3

183643506

-
ChimerDB4LUSCTCGA-33-4538-01ANAALADL2chr3

175345174

-ABCC5chr3

183643507

-
ChimerDB4LUSCTCGA-33-4538-01ANAALADL2chr3

175345174

+ABCC5chr3

183643507

-
ChimerDB4LUSCTCGA-33-4538NAALADL2chr3

175345174

+ABCC5chr3

183643507

-


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Fusion Gene ORF analysis for NAALADL2-ABCC5

check button Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
ORFHenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrand
5CDS-intronENST00000454872ENST00000382494NAALADL2chr3

175345173

+ABCC5chr3

183643506

-
5CDS-intronENST00000454872ENST00000382494NAALADL2chr3

175345174

+ABCC5chr3

183643507

-
5CDS-intronENST00000454872ENST00000392579NAALADL2chr3

175345173

+ABCC5chr3

183643506

-
5CDS-intronENST00000454872ENST00000392579NAALADL2chr3

175345174

+ABCC5chr3

183643507

-
5CDS-intronENST00000454872ENST00000427120NAALADL2chr3

175345173

+ABCC5chr3

183643506

-
5CDS-intronENST00000454872ENST00000427120NAALADL2chr3

175345174

+ABCC5chr3

183643507

-
5CDS-intronENST00000454872ENST00000446941NAALADL2chr3

175345173

+ABCC5chr3

183643506

-
5CDS-intronENST00000454872ENST00000446941NAALADL2chr3

175345174

+ABCC5chr3

183643507

-
5CDS-intronENST00000454872ENST00000492216NAALADL2chr3

175345173

+ABCC5chr3

183643506

-
5CDS-intronENST00000454872ENST00000492216NAALADL2chr3

175345174

+ABCC5chr3

183643507

-
In-frameENST00000454872ENST00000265586NAALADL2chr3

175345173

+ABCC5chr3

183643506

-
In-frameENST00000454872ENST00000265586NAALADL2chr3

175345174

+ABCC5chr3

183643507

-
In-frameENST00000454872ENST00000334444NAALADL2chr3

175345173

+ABCC5chr3

183643506

-
In-frameENST00000454872ENST00000334444NAALADL2chr3

175345174

+ABCC5chr3

183643507

-
intron-3CDSENST00000473253ENST00000265586NAALADL2chr3

175345173

+ABCC5chr3

183643506

-
intron-3CDSENST00000473253ENST00000265586NAALADL2chr3

175345174

+ABCC5chr3

183643507

-
intron-3CDSENST00000473253ENST00000334444NAALADL2chr3

175345173

+ABCC5chr3

183643506

-
intron-3CDSENST00000473253ENST00000334444NAALADL2chr3

175345174

+ABCC5chr3

183643507

-
intron-intronENST00000473253ENST00000382494NAALADL2chr3

175345173

+ABCC5chr3

183643506

-
intron-intronENST00000473253ENST00000382494NAALADL2chr3

175345174

+ABCC5chr3

183643507

-
intron-intronENST00000473253ENST00000392579NAALADL2chr3

175345173

+ABCC5chr3

183643506

-
intron-intronENST00000473253ENST00000392579NAALADL2chr3

175345174

+ABCC5chr3

183643507

-
intron-intronENST00000473253ENST00000427120NAALADL2chr3

175345173

+ABCC5chr3

183643506

-
intron-intronENST00000473253ENST00000427120NAALADL2chr3

175345174

+ABCC5chr3

183643507

-
intron-intronENST00000473253ENST00000446941NAALADL2chr3

175345173

+ABCC5chr3

183643506

-
intron-intronENST00000473253ENST00000446941NAALADL2chr3

175345174

+ABCC5chr3

183643507

-
intron-intronENST00000473253ENST00000492216NAALADL2chr3

175345173

+ABCC5chr3

183643506

-
intron-intronENST00000473253ENST00000492216NAALADL2chr3

175345174

+ABCC5chr3

183643507

-

check buttonORFfinder result based on the fusion transcript sequence of in-frame fusion genes.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandSeq length
(transcript)		BP loci
(transcript)		Predicted start
(transcript)		Predicted stop
(transcript)		Seq length
(amino acids)
ENST00000454872NAALADL2chr3175345174+ENST00000334444ABCC5chr3183643507-365720241282290720
ENST00000454872NAALADL2chr3175345174+ENST00000265586ABCC5chr3183643507-237720241282290720
ENST00000454872NAALADL2chr3175345173+ENST00000334444ABCC5chr3183643506-365720241282290720
ENST00000454872NAALADL2chr3175345173+ENST00000265586ABCC5chr3183643506-237720241282290720

check buttonDeepORF prediction of the coding potential based on the fusion transcript sequence of in-frame fusion genes. DeepORF is a coding potential classifier based on convolutional neural network by comparing the real Ribo-seq data. If the no-coding score < 0.5 and coding score > 0.5, then the in-frame fusion transcript is predicted as being likely translated.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandNo-coding scoreCoding score
ENST00000454872ENST00000334444NAALADL2chr3175345174+ABCC5chr3183643507-0.0004191580.9995808
ENST00000454872ENST00000265586NAALADL2chr3175345174+ABCC5chr3183643507-0.0007885960.99921143
ENST00000454872ENST00000334444NAALADL2chr3175345173+ABCC5chr3183643506-0.0004191580.9995808
ENST00000454872ENST00000265586NAALADL2chr3175345173+ABCC5chr3183643506-0.0007885960.99921143

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Fusion Genomic Features for NAALADL2-ABCC5


check buttonFusionAI prediction of the potential fusion gene breakpoint based on the pre-mature RNA sequence context (+/- 5kb of individual partner genes, total 20kb length sequence). FusionAI is a fusion gene breakpoint classifier based on convolutional neural network by comparing the fusion positive and negative sequence context of ~ 20K fusion gene data. From here, we can have the relative potentency of the 20K genomic sequence how individual sequnce will be likely used as the gene fusion breakpoints.
HgeneHchrHbpHstrandTgeneTchrTbpTstrand1-pp (fusion gene breakpoint)

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions. We integrated a total of 44 different types of human genomic feature loci information across five big categories including virus integration sites, repeats, structural variants, chromatin states, and gene expression regulation. More details are in help page.
genomic feature

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions that are ovelapped with the top 1% feature importance score regions. More details are in help page.

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Fusion Protein Features for NAALADL2-ABCC5


check button Four levels of functional features of fusion genes
Go to FGviewer search page for the most frequent breakpoint (https://ccsmweb.uth.edu/FGviewer/chr3:175345174/chr3:183643507)
- FGviewer provides the online visualization of the retention search of the protein functional features across DNA, RNA, protein, and pathological levels.
- How to search
1. Put your fusion gene symbol.
2. Press the tab key until there will be shown the breakpoint information filled.
4. Go down and press 'Search' tab twice.
4. Go down to have the hyperlink of the search result.
5. Click the hyperlink.
6. See the FGviewer result for your fusion gene.
FGviewer

check buttonMain function of each fusion partner protein. (from UniProt)
HgeneTgene
.ABCC5

O15440

FUNCTION: Transcriptional activator which is required for calcium-dependent dendritic growth and branching in cortical neurons. Recruits CREB-binding protein (CREBBP) to nuclear bodies. Component of the CREST-BRG1 complex, a multiprotein complex that regulates promoter activation by orchestrating a calcium-dependent release of a repressor complex and a recruitment of an activator complex. In resting neurons, transcription of the c-FOS promoter is inhibited by BRG1-dependent recruitment of a phospho-RB1-HDAC1 repressor complex. Upon calcium influx, RB1 is dephosphorylated by calcineurin, which leads to release of the repressor complex. At the same time, there is increased recruitment of CREBBP to the promoter by a CREST-dependent mechanism, which leads to transcriptional activation. The CREST-BRG1 complex also binds to the NR2B promoter, and activity-dependent induction of NR2B expression involves a release of HDAC1 and recruitment of CREBBP (By similarity). {ECO:0000250}.FUNCTION: Acts as a multispecific organic anion pump which can transport nucleotide analogs. Heme transporter required for the translocation of cytosolic heme to the secretory pathway (PubMed:24836561). {ECO:0000269|PubMed:10840050, ECO:0000269|PubMed:24836561}.

check buttonRetention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at

download page


* Minus value of BPloci means that the break pointn is located before the CDS.
- In-frame and retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneNAALADL2chr3:175345173chr3:183643506ENST00000454872+11141_121632796.0Topological domainCytoplasmic
HgeneNAALADL2chr3:175345174chr3:183643507ENST00000454872+11141_121632796.0Topological domainCytoplasmic
HgeneNAALADL2chr3:175345173chr3:183643506ENST00000454872+1114122_142632796.0TransmembraneHelical%3B Signal-anchor for type II membrane protein
HgeneNAALADL2chr3:175345174chr3:183643507ENST00000454872+1114122_142632796.0TransmembraneHelical%3B Signal-anchor for type II membrane protein
TgeneABCC5chr3:175345173chr3:183643506ENST00000382494071193_14270533.3333333333334DomainABC transporter 2
TgeneABCC5chr3:175345173chr3:183643506ENST0000038249407179_4590533.3333333333334DomainABC transmembrane type-1 1
TgeneABCC5chr3:175345173chr3:183643506ENST0000038249407562_7830533.3333333333334DomainABC transporter 1
TgeneABCC5chr3:175345173chr3:183643506ENST0000038249407859_11550533.3333333333334DomainABC transmembrane type-1 2
TgeneABCC5chr3:175345173chr3:183643506ENST00000392579061193_14270226.0DomainABC transporter 2
TgeneABCC5chr3:175345173chr3:183643506ENST0000039257906179_4590226.0DomainABC transmembrane type-1 1
TgeneABCC5chr3:175345173chr3:183643506ENST0000039257906562_7830226.0DomainABC transporter 1
TgeneABCC5chr3:175345173chr3:183643506ENST0000039257906859_11550226.0DomainABC transmembrane type-1 2
TgeneABCC5chr3:175345174chr3:183643507ENST00000382494071193_14270533.3333333333334DomainABC transporter 2
TgeneABCC5chr3:175345174chr3:183643507ENST0000038249407179_4590533.3333333333334DomainABC transmembrane type-1 1
TgeneABCC5chr3:175345174chr3:183643507ENST0000038249407562_7830533.3333333333334DomainABC transporter 1
TgeneABCC5chr3:175345174chr3:183643507ENST0000038249407859_11550533.3333333333334DomainABC transmembrane type-1 2
TgeneABCC5chr3:175345174chr3:183643507ENST00000392579061193_14270226.0DomainABC transporter 2
TgeneABCC5chr3:175345174chr3:183643507ENST0000039257906179_4590226.0DomainABC transmembrane type-1 1
TgeneABCC5chr3:175345174chr3:183643507ENST0000039257906562_7830226.0DomainABC transporter 1
TgeneABCC5chr3:175345174chr3:183643507ENST0000039257906859_11550226.0DomainABC transmembrane type-1 2
TgeneABCC5chr3:175345173chr3:183643506ENST00000382494071227_12340533.3333333333334Nucleotide bindingATP 2
TgeneABCC5chr3:175345173chr3:183643506ENST0000038249407595_6020533.3333333333334Nucleotide bindingATP 1
TgeneABCC5chr3:175345173chr3:183643506ENST00000392579061227_12340226.0Nucleotide bindingATP 2
TgeneABCC5chr3:175345173chr3:183643506ENST0000039257906595_6020226.0Nucleotide bindingATP 1
TgeneABCC5chr3:175345174chr3:183643507ENST00000382494071227_12340533.3333333333334Nucleotide bindingATP 2
TgeneABCC5chr3:175345174chr3:183643507ENST0000038249407595_6020533.3333333333334Nucleotide bindingATP 1
TgeneABCC5chr3:175345174chr3:183643507ENST00000392579061227_12340226.0Nucleotide bindingATP 2
TgeneABCC5chr3:175345174chr3:183643507ENST0000039257906595_6020226.0Nucleotide bindingATP 1
TgeneABCC5chr3:175345173chr3:183643506ENST00000382494071018_10380533.3333333333334TransmembraneHelical
TgeneABCC5chr3:175345173chr3:183643506ENST00000382494071104_11240533.3333333333334TransmembraneHelical
TgeneABCC5chr3:175345173chr3:183643506ENST00000382494071127_11470533.3333333333334TransmembraneHelical
TgeneABCC5chr3:175345173chr3:183643506ENST0000038249407179_1990533.3333333333334TransmembraneHelical
TgeneABCC5chr3:175345173chr3:183643506ENST0000038249407219_2390533.3333333333334TransmembraneHelical
TgeneABCC5chr3:175345173chr3:183643506ENST0000038249407296_3160533.3333333333334TransmembraneHelical
TgeneABCC5chr3:175345173chr3:183643506ENST0000038249407317_3370533.3333333333334TransmembraneHelical
TgeneABCC5chr3:175345173chr3:183643506ENST0000038249407400_4200533.3333333333334TransmembraneHelical
TgeneABCC5chr3:175345173chr3:183643506ENST0000038249407434_4540533.3333333333334TransmembraneHelical
TgeneABCC5chr3:175345173chr3:183643506ENST0000038249407608_6280533.3333333333334TransmembraneHelical
TgeneABCC5chr3:175345173chr3:183643506ENST0000038249407848_8680533.3333333333334TransmembraneHelical
TgeneABCC5chr3:175345173chr3:183643506ENST0000038249407917_9370533.3333333333334TransmembraneHelical
TgeneABCC5chr3:175345173chr3:183643506ENST0000038249407997_10170533.3333333333334TransmembraneHelical
TgeneABCC5chr3:175345173chr3:183643506ENST00000392579061018_10380226.0TransmembraneHelical
TgeneABCC5chr3:175345173chr3:183643506ENST00000392579061104_11240226.0TransmembraneHelical
TgeneABCC5chr3:175345173chr3:183643506ENST00000392579061127_11470226.0TransmembraneHelical
TgeneABCC5chr3:175345173chr3:183643506ENST0000039257906179_1990226.0TransmembraneHelical
TgeneABCC5chr3:175345173chr3:183643506ENST0000039257906219_2390226.0TransmembraneHelical
TgeneABCC5chr3:175345173chr3:183643506ENST0000039257906296_3160226.0TransmembraneHelical
TgeneABCC5chr3:175345173chr3:183643506ENST0000039257906317_3370226.0TransmembraneHelical
TgeneABCC5chr3:175345173chr3:183643506ENST0000039257906400_4200226.0TransmembraneHelical
TgeneABCC5chr3:175345173chr3:183643506ENST0000039257906434_4540226.0TransmembraneHelical
TgeneABCC5chr3:175345173chr3:183643506ENST0000039257906608_6280226.0TransmembraneHelical
TgeneABCC5chr3:175345173chr3:183643506ENST0000039257906848_8680226.0TransmembraneHelical
TgeneABCC5chr3:175345173chr3:183643506ENST0000039257906917_9370226.0TransmembraneHelical
TgeneABCC5chr3:175345173chr3:183643506ENST0000039257906997_10170226.0TransmembraneHelical
TgeneABCC5chr3:175345174chr3:183643507ENST00000382494071018_10380533.3333333333334TransmembraneHelical
TgeneABCC5chr3:175345174chr3:183643507ENST00000382494071104_11240533.3333333333334TransmembraneHelical
TgeneABCC5chr3:175345174chr3:183643507ENST00000382494071127_11470533.3333333333334TransmembraneHelical
TgeneABCC5chr3:175345174chr3:183643507ENST0000038249407179_1990533.3333333333334TransmembraneHelical
TgeneABCC5chr3:175345174chr3:183643507ENST0000038249407219_2390533.3333333333334TransmembraneHelical
TgeneABCC5chr3:175345174chr3:183643507ENST0000038249407296_3160533.3333333333334TransmembraneHelical
TgeneABCC5chr3:175345174chr3:183643507ENST0000038249407317_3370533.3333333333334TransmembraneHelical
TgeneABCC5chr3:175345174chr3:183643507ENST0000038249407400_4200533.3333333333334TransmembraneHelical
TgeneABCC5chr3:175345174chr3:183643507ENST0000038249407434_4540533.3333333333334TransmembraneHelical
TgeneABCC5chr3:175345174chr3:183643507ENST0000038249407608_6280533.3333333333334TransmembraneHelical
TgeneABCC5chr3:175345174chr3:183643507ENST0000038249407848_8680533.3333333333334TransmembraneHelical
TgeneABCC5chr3:175345174chr3:183643507ENST0000038249407917_9370533.3333333333334TransmembraneHelical
TgeneABCC5chr3:175345174chr3:183643507ENST0000038249407997_10170533.3333333333334TransmembraneHelical
TgeneABCC5chr3:175345174chr3:183643507ENST00000392579061018_10380226.0TransmembraneHelical
TgeneABCC5chr3:175345174chr3:183643507ENST00000392579061104_11240226.0TransmembraneHelical
TgeneABCC5chr3:175345174chr3:183643507ENST00000392579061127_11470226.0TransmembraneHelical
TgeneABCC5chr3:175345174chr3:183643507ENST0000039257906179_1990226.0TransmembraneHelical
TgeneABCC5chr3:175345174chr3:183643507ENST0000039257906219_2390226.0TransmembraneHelical
TgeneABCC5chr3:175345174chr3:183643507ENST0000039257906296_3160226.0TransmembraneHelical
TgeneABCC5chr3:175345174chr3:183643507ENST0000039257906317_3370226.0TransmembraneHelical
TgeneABCC5chr3:175345174chr3:183643507ENST0000039257906400_4200226.0TransmembraneHelical
TgeneABCC5chr3:175345174chr3:183643507ENST0000039257906434_4540226.0TransmembraneHelical
TgeneABCC5chr3:175345174chr3:183643507ENST0000039257906608_6280226.0TransmembraneHelical
TgeneABCC5chr3:175345174chr3:183643507ENST0000039257906848_8680226.0TransmembraneHelical
TgeneABCC5chr3:175345174chr3:183643507ENST0000039257906917_9370226.0TransmembraneHelical
TgeneABCC5chr3:175345174chr3:183643507ENST0000039257906997_10170226.0TransmembraneHelical

- In-frame and not-retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneNAALADL2chr3:175345173chr3:183643506ENST00000454872+1114143_795632796.0Topological domainExtracellular
HgeneNAALADL2chr3:175345174chr3:183643507ENST00000454872+1114143_795632796.0Topological domainExtracellular
TgeneABCC5chr3:175345173chr3:183643506ENST0000033444427301193_142713491438.0DomainABC transporter 2
TgeneABCC5chr3:175345173chr3:183643506ENST000003344442730179_45913491438.0DomainABC transmembrane type-1 1
TgeneABCC5chr3:175345173chr3:183643506ENST000003344442730562_78313491438.0DomainABC transporter 1
TgeneABCC5chr3:175345173chr3:183643506ENST000003344442730859_115513491438.0DomainABC transmembrane type-1 2
TgeneABCC5chr3:175345174chr3:183643507ENST0000033444427301193_142713491438.0DomainABC transporter 2
TgeneABCC5chr3:175345174chr3:183643507ENST000003344442730179_45913491438.0DomainABC transmembrane type-1 1
TgeneABCC5chr3:175345174chr3:183643507ENST000003344442730562_78313491438.0DomainABC transporter 1
TgeneABCC5chr3:175345174chr3:183643507ENST000003344442730859_115513491438.0DomainABC transmembrane type-1 2
TgeneABCC5chr3:175345173chr3:183643506ENST0000033444427301227_123413491438.0Nucleotide bindingATP 2
TgeneABCC5chr3:175345173chr3:183643506ENST000003344442730595_60213491438.0Nucleotide bindingATP 1
TgeneABCC5chr3:175345174chr3:183643507ENST0000033444427301227_123413491438.0Nucleotide bindingATP 2
TgeneABCC5chr3:175345174chr3:183643507ENST000003344442730595_60213491438.0Nucleotide bindingATP 1
TgeneABCC5chr3:175345173chr3:183643506ENST0000033444427301018_103813491438.0TransmembraneHelical
TgeneABCC5chr3:175345173chr3:183643506ENST0000033444427301104_112413491438.0TransmembraneHelical
TgeneABCC5chr3:175345173chr3:183643506ENST0000033444427301127_114713491438.0TransmembraneHelical
TgeneABCC5chr3:175345173chr3:183643506ENST000003344442730179_19913491438.0TransmembraneHelical
TgeneABCC5chr3:175345173chr3:183643506ENST000003344442730219_23913491438.0TransmembraneHelical
TgeneABCC5chr3:175345173chr3:183643506ENST000003344442730296_31613491438.0TransmembraneHelical
TgeneABCC5chr3:175345173chr3:183643506ENST000003344442730317_33713491438.0TransmembraneHelical
TgeneABCC5chr3:175345173chr3:183643506ENST000003344442730400_42013491438.0TransmembraneHelical
TgeneABCC5chr3:175345173chr3:183643506ENST000003344442730434_45413491438.0TransmembraneHelical
TgeneABCC5chr3:175345173chr3:183643506ENST000003344442730608_62813491438.0TransmembraneHelical
TgeneABCC5chr3:175345173chr3:183643506ENST000003344442730848_86813491438.0TransmembraneHelical
TgeneABCC5chr3:175345173chr3:183643506ENST000003344442730917_93713491438.0TransmembraneHelical
TgeneABCC5chr3:175345173chr3:183643506ENST000003344442730997_101713491438.0TransmembraneHelical
TgeneABCC5chr3:175345174chr3:183643507ENST0000033444427301018_103813491438.0TransmembraneHelical
TgeneABCC5chr3:175345174chr3:183643507ENST0000033444427301104_112413491438.0TransmembraneHelical
TgeneABCC5chr3:175345174chr3:183643507ENST0000033444427301127_114713491438.0TransmembraneHelical
TgeneABCC5chr3:175345174chr3:183643507ENST000003344442730179_19913491438.0TransmembraneHelical
TgeneABCC5chr3:175345174chr3:183643507ENST000003344442730219_23913491438.0TransmembraneHelical
TgeneABCC5chr3:175345174chr3:183643507ENST000003344442730296_31613491438.0TransmembraneHelical
TgeneABCC5chr3:175345174chr3:183643507ENST000003344442730317_33713491438.0TransmembraneHelical
TgeneABCC5chr3:175345174chr3:183643507ENST000003344442730400_42013491438.0TransmembraneHelical
TgeneABCC5chr3:175345174chr3:183643507ENST000003344442730434_45413491438.0TransmembraneHelical
TgeneABCC5chr3:175345174chr3:183643507ENST000003344442730608_62813491438.0TransmembraneHelical
TgeneABCC5chr3:175345174chr3:183643507ENST000003344442730848_86813491438.0TransmembraneHelical
TgeneABCC5chr3:175345174chr3:183643507ENST000003344442730917_93713491438.0TransmembraneHelical
TgeneABCC5chr3:175345174chr3:183643507ENST000003344442730997_101713491438.0TransmembraneHelical


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Fusion Gene Sequence for NAALADL2-ABCC5


check button For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. To have fusion amino acid sequence, we ran ORFfinder and chose the longest ORF among the all predicted ones.
>57022_57022_1_NAALADL2-ABCC5_NAALADL2_chr3_175345173_ENST00000454872_ABCC5_chr3_183643506_ENST00000265586_length(transcript)=2377nt_BP=2024nt
TTATTCACAGAAGAAAGCAGGTAGTATACTGTTACAATACTACAGTAGAAAGTCAGAAGGTCACAAAGCTTGCAGGGTAAGTGACACAAC
TTGAAACTGCTTGGCCCTCTTTAAAAAGAAATAATAAAATGGGAGAGAATGAAGCAAGTTTACCTAACACGTCTTTGCAAGGTAAAAAGA
TGGCCTATCAGAAGGTCCATGCAGATCAAAGAGCTCCAGGACACTCACAGTACTTAGACAATGATGACCTTCAAGCCACTGCCCTTGACT
TAGAGTGGGACATGGAGAAGGAACTAGAGGAGTCTGGTTTTGACCAATTCCAGCTAGACGGTGCTGAGAATCAGAACCTAGGGCATTCAG
AGACTATAGACCTCAATCTTGATTCCATTCAACCAGCAACTTCACCCAAAGGAAGGTTCCAGAGACTTCAAGAAGAATCTGACTACATTA
CCCATTATACACGATCTGCACCAAAGAGCAATCGCTGCAACTTTTGCCACGTCTTAAAAATACTTTGCACAGCCACCATTTTATTTATTT
TTGGGATTTTGATAGGTTATTATGTACATACAAATTGCCCTTCAGATGCTCCATCTTCAGGAACAGTTGATCCTCAGTTATATCAAGAGA
TTCTCAAGACAATCCAGGCAGAAGATATTAAGAAGTCTTTCAGAAATTTGGTACAACTATATAAAAATGAAGATGACATGGAAATTTCAA
AGAAGATTAAGACTCAGTGGACCTCTTTGGGCCTAGAAGATGTACAGTTTGTAAATTACTCTGTGCTGCTTGATCTGCCAGGCCCTTCTC
CCAGCACTGTGACTCTGAGCAGCAGTGGTCAATGCTTTCATCCTAATGGCCAGCCTTGCAGTGAAGAAGCCAGAAAAGATAGCAGCCAAG
ACCTGCTCTATTCATATGCAGCCTATTCTGCCAAAGGAACTCTCAAGGCTGAAGTCATCGATGTGAGTTATGGAATGGCAGATGATTTAA
AAAGGATTAGGAAAATAAAAAACGTAACAAATCAGATCGCACTCCTGAAATTAGGAAAATTGCCACTGCTTTATAAGCTTTCCTCATTGG
AAAAGGCTGGATTTGGAGGTGTTCTTCTGTATATCGATCCTTGTGATTTGCCAAAGACTGTGAATCCTAGCCATGATACCTTCATGGTGT
CACTGAATCCAGGAGGAGACCCTTCTACGCCTGGTTACCCAAGTGTCGATGAAAGTTTTAGACAAAGCCGATCAAACCTCACCTCTCTAT
TAGTGCAGCCCATCTCTGCACCCCTCGTTGCAAAACTGATCTCTTCGCCAAAAGCTAGAACCAAAAATGAAGCGTGTAGCTCTCTAGAGC
TTCCAAATAATGAAATAAGAGTCGTCAGCATGCAAGTTCAGACAGTCACAAAATTGAAAACAGTTACTAATGTTGTTGGATTTGTAATGG
GCTTGACATCTCCAGACCGGTATATCATAGTTGGCAGCCATCATCACACTGCACACAGTTATAATGGACAAGAATGGGCCAGTAGTACTG
CAATAATCACAGCGTTTATCCGTGCCTTGATGTCAAAAGTTAAGAGAGGGTGGAGACCAGACCGAACTATTGTTTTCTGTTCTTGGGGAG
GAACAGCTTTTGGCAATATTGGCTCATATGAATGGGGAGAGGATTTCAAGAAGGTTCTTCAGAAAAATGTTGTGGCTTATATTAGCCTCC
ACAGTCCCATAAGGGGGAACTCTAGTCTGTATCCTGTAGCATCACCATCTCTTCAGCAACTGGTAGTAGAGAAAAATAATTTCAACTGTA
CCAGAAGAGCCCAGTGCCCAGAAACCAATATCAGTTCTATACAGATACAAGGTGATGCTGATTATTTCATCAACCATCTTGGAGTTCCCA
TCGTGCAGTTTGCTTACGAGGACATCAAAACATTAGAGGGTCCAAGTTTTCTCTCCGAGGCCCGTTTTTCTACACGAGCAACAAAAATTG
AAGAAATGGATCCCTCTTTCAACCTTCATGAAACCATTACTAAGATTCTGATTTTAGATGAAGCCACAGCTGCCATGGACACAGAGACAG
ACTTATTGATTCAAGAGACCATCCGAGAAGCATTTGCAGACTGTACCATGCTGACCATTGCCCATCGCCTGCACACGGTTCTAGGCTCCG
ATAGGATTATGGTGCTGGCCCAGGGACAGGTGGTGGAGTTTGACACCCCATCGGTCCTTCTGTCCAACGACAGTTCCCGATTCTATGCCA
TGTTTGCTGCTGCAGAGAACAAGGTCGCTGTCAAGGGCTGACTCCTCCCTGTTGACGAAGTCTCTTTTCTTTAGAGCATTGCCATTCCCT

>57022_57022_1_NAALADL2-ABCC5_NAALADL2_chr3_175345173_ENST00000454872_ABCC5_chr3_183643506_ENST00000265586_length(amino acids)=720AA_BP=632
MGENEASLPNTSLQGKKMAYQKVHADQRAPGHSQYLDNDDLQATALDLEWDMEKELEESGFDQFQLDGAENQNLGHSETIDLNLDSIQPA
TSPKGRFQRLQEESDYITHYTRSAPKSNRCNFCHVLKILCTATILFIFGILIGYYVHTNCPSDAPSSGTVDPQLYQEILKTIQAEDIKKS
FRNLVQLYKNEDDMEISKKIKTQWTSLGLEDVQFVNYSVLLDLPGPSPSTVTLSSSGQCFHPNGQPCSEEARKDSSQDLLYSYAAYSAKG
TLKAEVIDVSYGMADDLKRIRKIKNVTNQIALLKLGKLPLLYKLSSLEKAGFGGVLLYIDPCDLPKTVNPSHDTFMVSLNPGGDPSTPGY
PSVDESFRQSRSNLTSLLVQPISAPLVAKLISSPKARTKNEACSSLELPNNEIRVVSMQVQTVTKLKTVTNVVGFVMGLTSPDRYIIVGS
HHHTAHSYNGQEWASSTAIITAFIRALMSKVKRGWRPDRTIVFCSWGGTAFGNIGSYEWGEDFKKVLQKNVVAYISLHSPIRGNSSLYPV
ASPSLQQLVVEKNNFNCTRRAQCPETNISSIQIQGDADYFINHLGVPIVQFAYEDIKTLEGPSFLSEARFSTRATKIEEMDPSFNLHETI
TKILILDEATAAMDTETDLLIQETIREAFADCTMLTIAHRLHTVLGSDRIMVLAQGQVVEFDTPSVLLSNDSSRFYAMFAAAENKVAVKG

--------------------------------------------------------------
>57022_57022_2_NAALADL2-ABCC5_NAALADL2_chr3_175345173_ENST00000454872_ABCC5_chr3_183643506_ENST00000334444_length(transcript)=3657nt_BP=2024nt
TTATTCACAGAAGAAAGCAGGTAGTATACTGTTACAATACTACAGTAGAAAGTCAGAAGGTCACAAAGCTTGCAGGGTAAGTGACACAAC
TTGAAACTGCTTGGCCCTCTTTAAAAAGAAATAATAAAATGGGAGAGAATGAAGCAAGTTTACCTAACACGTCTTTGCAAGGTAAAAAGA
TGGCCTATCAGAAGGTCCATGCAGATCAAAGAGCTCCAGGACACTCACAGTACTTAGACAATGATGACCTTCAAGCCACTGCCCTTGACT
TAGAGTGGGACATGGAGAAGGAACTAGAGGAGTCTGGTTTTGACCAATTCCAGCTAGACGGTGCTGAGAATCAGAACCTAGGGCATTCAG
AGACTATAGACCTCAATCTTGATTCCATTCAACCAGCAACTTCACCCAAAGGAAGGTTCCAGAGACTTCAAGAAGAATCTGACTACATTA
CCCATTATACACGATCTGCACCAAAGAGCAATCGCTGCAACTTTTGCCACGTCTTAAAAATACTTTGCACAGCCACCATTTTATTTATTT
TTGGGATTTTGATAGGTTATTATGTACATACAAATTGCCCTTCAGATGCTCCATCTTCAGGAACAGTTGATCCTCAGTTATATCAAGAGA
TTCTCAAGACAATCCAGGCAGAAGATATTAAGAAGTCTTTCAGAAATTTGGTACAACTATATAAAAATGAAGATGACATGGAAATTTCAA
AGAAGATTAAGACTCAGTGGACCTCTTTGGGCCTAGAAGATGTACAGTTTGTAAATTACTCTGTGCTGCTTGATCTGCCAGGCCCTTCTC
CCAGCACTGTGACTCTGAGCAGCAGTGGTCAATGCTTTCATCCTAATGGCCAGCCTTGCAGTGAAGAAGCCAGAAAAGATAGCAGCCAAG
ACCTGCTCTATTCATATGCAGCCTATTCTGCCAAAGGAACTCTCAAGGCTGAAGTCATCGATGTGAGTTATGGAATGGCAGATGATTTAA
AAAGGATTAGGAAAATAAAAAACGTAACAAATCAGATCGCACTCCTGAAATTAGGAAAATTGCCACTGCTTTATAAGCTTTCCTCATTGG
AAAAGGCTGGATTTGGAGGTGTTCTTCTGTATATCGATCCTTGTGATTTGCCAAAGACTGTGAATCCTAGCCATGATACCTTCATGGTGT
CACTGAATCCAGGAGGAGACCCTTCTACGCCTGGTTACCCAAGTGTCGATGAAAGTTTTAGACAAAGCCGATCAAACCTCACCTCTCTAT
TAGTGCAGCCCATCTCTGCACCCCTCGTTGCAAAACTGATCTCTTCGCCAAAAGCTAGAACCAAAAATGAAGCGTGTAGCTCTCTAGAGC
TTCCAAATAATGAAATAAGAGTCGTCAGCATGCAAGTTCAGACAGTCACAAAATTGAAAACAGTTACTAATGTTGTTGGATTTGTAATGG
GCTTGACATCTCCAGACCGGTATATCATAGTTGGCAGCCATCATCACACTGCACACAGTTATAATGGACAAGAATGGGCCAGTAGTACTG
CAATAATCACAGCGTTTATCCGTGCCTTGATGTCAAAAGTTAAGAGAGGGTGGAGACCAGACCGAACTATTGTTTTCTGTTCTTGGGGAG
GAACAGCTTTTGGCAATATTGGCTCATATGAATGGGGAGAGGATTTCAAGAAGGTTCTTCAGAAAAATGTTGTGGCTTATATTAGCCTCC
ACAGTCCCATAAGGGGGAACTCTAGTCTGTATCCTGTAGCATCACCATCTCTTCAGCAACTGGTAGTAGAGAAAAATAATTTCAACTGTA
CCAGAAGAGCCCAGTGCCCAGAAACCAATATCAGTTCTATACAGATACAAGGTGATGCTGATTATTTCATCAACCATCTTGGAGTTCCCA
TCGTGCAGTTTGCTTACGAGGACATCAAAACATTAGAGGGTCCAAGTTTTCTCTCCGAGGCCCGTTTTTCTACACGAGCAACAAAAATTG
AAGAAATGGATCCCTCTTTCAACCTTCATGAAACCATTACTAAGATTCTGATTTTAGATGAAGCCACAGCTGCCATGGACACAGAGACAG
ACTTATTGATTCAAGAGACCATCCGAGAAGCATTTGCAGACTGTACCATGCTGACCATTGCCCATCGCCTGCACACGGTTCTAGGCTCCG
ATAGGATTATGGTGCTGGCCCAGGGACAGGTGGTGGAGTTTGACACCCCATCGGTCCTTCTGTCCAACGACAGTTCCCGATTCTATGCCA
TGTTTGCTGCTGCAGAGAACAAGGTCGCTGTCAAGGGCTGACTCCTCCCTGTTGACGAAGTCTCTTTTCTTTAGAGCATTGCCATTCCCT
GCCTGGGGCGGGCCCCTCATCGCGTCCTCCTACCGAAACCTTGCCTTTCTCGATTTTATCTTTCGCACAGCAGTTCCGGATTGGCTTGTG
TGTTTCACTTTTAGGGAGAGTCATATTTTGATTATTGTATTTATTCCATATTCATGTAAACAAAATTTAGTTTTTGTTCTTAATTGCACT
CTAAAAGGTTCAGGGAACCGTTATTATAATTGTATCAGAGGCCTATAATGAAGCTTTATACGTGTAGCTATATCTATATATAATTCTGTA
CATAGCCTATATTTACAGTGAAAATGTAAGCTGTTTATTTTATATTAAAATAAGCACTGTGCTAATAACAGTGCATATTCCTTTCTATCA
TTTTTGTACAGTTTGCTGTACTAGAGATCTGGTTTTGCTATTAGACTGTAGGAAGAGTAGCATTTCATTCTTCTCTAGCTGGTGGTTTCA
CGGTGCCAGGTTTTCTGGGTGTCCAAAGGAAGACGTGTGGCAATAGTGGGCCCTCCGACAGCCCCCTCTGCCGCCTCCCCACGGCCGCTC
CAGGGGTGGCTGGAGACGGGTGGGCGGCTGGAGACCATGCAGAGCGCCGTGAGTTCTCAGGGCTCCTGCCTTCTGTCCTGGTGTCACTTA
CTGTTTCTGTCAGGAGAGCAGCGGGGCGAAGCCCAGGCCCCTTTTCACTCCCTCCATCAAGAATGGGGATCACAGAGACATTCCTCCGAG
CCGGGGAGTTTCTTTCCTGCCTTCTTCTTTTTGCTGTTGTTTCTAAACAAGAATCAGTCTATCCACAGAGAGTCCCACTGCCTCAGGTTC
CTATGGCTGGCCACTGCACAGAGCTCTCCAGCTCCAAGACCTGTTGGTTCCAAGCCCTGGAGCCAACTGCTGCTTTTTGAGGTGGCACTT
TTTCATTTGCCTATTCCCACACCTCCACAGTTCAGTGGCAGGGCTCAGGATTTCGTGGGTCTGTTTTCCTTTCTCACCGCAGTCGTCGCA
CAGTCTCTCTCTCTCTCTCCCCTCAAAGTCTGCAACTTTAAGCAGCTCTTGCTAATCAGTGTCTCACACTGGCGTAGAAGTTTTTGTACT
GTAAAGAGACCTACCTCAGGTTGCTGGTTGCTGTGTGGTTTGGTGTGTTCCCGCAAACCCCCTTTGTGCTGTGGGGCTGGTAGCTCAGGT
GGGCGTGGTCACTGCTGTCATCAATTGAATGGTCAGCGTTGCATGTCGTGACCAACTAGACATTCTGTCGCCTTAGCATGTTTGCTGAAC

>57022_57022_2_NAALADL2-ABCC5_NAALADL2_chr3_175345173_ENST00000454872_ABCC5_chr3_183643506_ENST00000334444_length(amino acids)=720AA_BP=632
MGENEASLPNTSLQGKKMAYQKVHADQRAPGHSQYLDNDDLQATALDLEWDMEKELEESGFDQFQLDGAENQNLGHSETIDLNLDSIQPA
TSPKGRFQRLQEESDYITHYTRSAPKSNRCNFCHVLKILCTATILFIFGILIGYYVHTNCPSDAPSSGTVDPQLYQEILKTIQAEDIKKS
FRNLVQLYKNEDDMEISKKIKTQWTSLGLEDVQFVNYSVLLDLPGPSPSTVTLSSSGQCFHPNGQPCSEEARKDSSQDLLYSYAAYSAKG
TLKAEVIDVSYGMADDLKRIRKIKNVTNQIALLKLGKLPLLYKLSSLEKAGFGGVLLYIDPCDLPKTVNPSHDTFMVSLNPGGDPSTPGY
PSVDESFRQSRSNLTSLLVQPISAPLVAKLISSPKARTKNEACSSLELPNNEIRVVSMQVQTVTKLKTVTNVVGFVMGLTSPDRYIIVGS
HHHTAHSYNGQEWASSTAIITAFIRALMSKVKRGWRPDRTIVFCSWGGTAFGNIGSYEWGEDFKKVLQKNVVAYISLHSPIRGNSSLYPV
ASPSLQQLVVEKNNFNCTRRAQCPETNISSIQIQGDADYFINHLGVPIVQFAYEDIKTLEGPSFLSEARFSTRATKIEEMDPSFNLHETI
TKILILDEATAAMDTETDLLIQETIREAFADCTMLTIAHRLHTVLGSDRIMVLAQGQVVEFDTPSVLLSNDSSRFYAMFAAAENKVAVKG

--------------------------------------------------------------
>57022_57022_3_NAALADL2-ABCC5_NAALADL2_chr3_175345174_ENST00000454872_ABCC5_chr3_183643507_ENST00000265586_length(transcript)=2377nt_BP=2024nt
TTATTCACAGAAGAAAGCAGGTAGTATACTGTTACAATACTACAGTAGAAAGTCAGAAGGTCACAAAGCTTGCAGGGTAAGTGACACAAC
TTGAAACTGCTTGGCCCTCTTTAAAAAGAAATAATAAAATGGGAGAGAATGAAGCAAGTTTACCTAACACGTCTTTGCAAGGTAAAAAGA
TGGCCTATCAGAAGGTCCATGCAGATCAAAGAGCTCCAGGACACTCACAGTACTTAGACAATGATGACCTTCAAGCCACTGCCCTTGACT
TAGAGTGGGACATGGAGAAGGAACTAGAGGAGTCTGGTTTTGACCAATTCCAGCTAGACGGTGCTGAGAATCAGAACCTAGGGCATTCAG
AGACTATAGACCTCAATCTTGATTCCATTCAACCAGCAACTTCACCCAAAGGAAGGTTCCAGAGACTTCAAGAAGAATCTGACTACATTA
CCCATTATACACGATCTGCACCAAAGAGCAATCGCTGCAACTTTTGCCACGTCTTAAAAATACTTTGCACAGCCACCATTTTATTTATTT
TTGGGATTTTGATAGGTTATTATGTACATACAAATTGCCCTTCAGATGCTCCATCTTCAGGAACAGTTGATCCTCAGTTATATCAAGAGA
TTCTCAAGACAATCCAGGCAGAAGATATTAAGAAGTCTTTCAGAAATTTGGTACAACTATATAAAAATGAAGATGACATGGAAATTTCAA
AGAAGATTAAGACTCAGTGGACCTCTTTGGGCCTAGAAGATGTACAGTTTGTAAATTACTCTGTGCTGCTTGATCTGCCAGGCCCTTCTC
CCAGCACTGTGACTCTGAGCAGCAGTGGTCAATGCTTTCATCCTAATGGCCAGCCTTGCAGTGAAGAAGCCAGAAAAGATAGCAGCCAAG
ACCTGCTCTATTCATATGCAGCCTATTCTGCCAAAGGAACTCTCAAGGCTGAAGTCATCGATGTGAGTTATGGAATGGCAGATGATTTAA
AAAGGATTAGGAAAATAAAAAACGTAACAAATCAGATCGCACTCCTGAAATTAGGAAAATTGCCACTGCTTTATAAGCTTTCCTCATTGG
AAAAGGCTGGATTTGGAGGTGTTCTTCTGTATATCGATCCTTGTGATTTGCCAAAGACTGTGAATCCTAGCCATGATACCTTCATGGTGT
CACTGAATCCAGGAGGAGACCCTTCTACGCCTGGTTACCCAAGTGTCGATGAAAGTTTTAGACAAAGCCGATCAAACCTCACCTCTCTAT
TAGTGCAGCCCATCTCTGCACCCCTCGTTGCAAAACTGATCTCTTCGCCAAAAGCTAGAACCAAAAATGAAGCGTGTAGCTCTCTAGAGC
TTCCAAATAATGAAATAAGAGTCGTCAGCATGCAAGTTCAGACAGTCACAAAATTGAAAACAGTTACTAATGTTGTTGGATTTGTAATGG
GCTTGACATCTCCAGACCGGTATATCATAGTTGGCAGCCATCATCACACTGCACACAGTTATAATGGACAAGAATGGGCCAGTAGTACTG
CAATAATCACAGCGTTTATCCGTGCCTTGATGTCAAAAGTTAAGAGAGGGTGGAGACCAGACCGAACTATTGTTTTCTGTTCTTGGGGAG
GAACAGCTTTTGGCAATATTGGCTCATATGAATGGGGAGAGGATTTCAAGAAGGTTCTTCAGAAAAATGTTGTGGCTTATATTAGCCTCC
ACAGTCCCATAAGGGGGAACTCTAGTCTGTATCCTGTAGCATCACCATCTCTTCAGCAACTGGTAGTAGAGAAAAATAATTTCAACTGTA
CCAGAAGAGCCCAGTGCCCAGAAACCAATATCAGTTCTATACAGATACAAGGTGATGCTGATTATTTCATCAACCATCTTGGAGTTCCCA
TCGTGCAGTTTGCTTACGAGGACATCAAAACATTAGAGGGTCCAAGTTTTCTCTCCGAGGCCCGTTTTTCTACACGAGCAACAAAAATTG
AAGAAATGGATCCCTCTTTCAACCTTCATGAAACCATTACTAAGATTCTGATTTTAGATGAAGCCACAGCTGCCATGGACACAGAGACAG
ACTTATTGATTCAAGAGACCATCCGAGAAGCATTTGCAGACTGTACCATGCTGACCATTGCCCATCGCCTGCACACGGTTCTAGGCTCCG
ATAGGATTATGGTGCTGGCCCAGGGACAGGTGGTGGAGTTTGACACCCCATCGGTCCTTCTGTCCAACGACAGTTCCCGATTCTATGCCA
TGTTTGCTGCTGCAGAGAACAAGGTCGCTGTCAAGGGCTGACTCCTCCCTGTTGACGAAGTCTCTTTTCTTTAGAGCATTGCCATTCCCT

>57022_57022_3_NAALADL2-ABCC5_NAALADL2_chr3_175345174_ENST00000454872_ABCC5_chr3_183643507_ENST00000265586_length(amino acids)=720AA_BP=632
MGENEASLPNTSLQGKKMAYQKVHADQRAPGHSQYLDNDDLQATALDLEWDMEKELEESGFDQFQLDGAENQNLGHSETIDLNLDSIQPA
TSPKGRFQRLQEESDYITHYTRSAPKSNRCNFCHVLKILCTATILFIFGILIGYYVHTNCPSDAPSSGTVDPQLYQEILKTIQAEDIKKS
FRNLVQLYKNEDDMEISKKIKTQWTSLGLEDVQFVNYSVLLDLPGPSPSTVTLSSSGQCFHPNGQPCSEEARKDSSQDLLYSYAAYSAKG
TLKAEVIDVSYGMADDLKRIRKIKNVTNQIALLKLGKLPLLYKLSSLEKAGFGGVLLYIDPCDLPKTVNPSHDTFMVSLNPGGDPSTPGY
PSVDESFRQSRSNLTSLLVQPISAPLVAKLISSPKARTKNEACSSLELPNNEIRVVSMQVQTVTKLKTVTNVVGFVMGLTSPDRYIIVGS
HHHTAHSYNGQEWASSTAIITAFIRALMSKVKRGWRPDRTIVFCSWGGTAFGNIGSYEWGEDFKKVLQKNVVAYISLHSPIRGNSSLYPV
ASPSLQQLVVEKNNFNCTRRAQCPETNISSIQIQGDADYFINHLGVPIVQFAYEDIKTLEGPSFLSEARFSTRATKIEEMDPSFNLHETI
TKILILDEATAAMDTETDLLIQETIREAFADCTMLTIAHRLHTVLGSDRIMVLAQGQVVEFDTPSVLLSNDSSRFYAMFAAAENKVAVKG

--------------------------------------------------------------
>57022_57022_4_NAALADL2-ABCC5_NAALADL2_chr3_175345174_ENST00000454872_ABCC5_chr3_183643507_ENST00000334444_length(transcript)=3657nt_BP=2024nt
TTATTCACAGAAGAAAGCAGGTAGTATACTGTTACAATACTACAGTAGAAAGTCAGAAGGTCACAAAGCTTGCAGGGTAAGTGACACAAC
TTGAAACTGCTTGGCCCTCTTTAAAAAGAAATAATAAAATGGGAGAGAATGAAGCAAGTTTACCTAACACGTCTTTGCAAGGTAAAAAGA
TGGCCTATCAGAAGGTCCATGCAGATCAAAGAGCTCCAGGACACTCACAGTACTTAGACAATGATGACCTTCAAGCCACTGCCCTTGACT
TAGAGTGGGACATGGAGAAGGAACTAGAGGAGTCTGGTTTTGACCAATTCCAGCTAGACGGTGCTGAGAATCAGAACCTAGGGCATTCAG
AGACTATAGACCTCAATCTTGATTCCATTCAACCAGCAACTTCACCCAAAGGAAGGTTCCAGAGACTTCAAGAAGAATCTGACTACATTA
CCCATTATACACGATCTGCACCAAAGAGCAATCGCTGCAACTTTTGCCACGTCTTAAAAATACTTTGCACAGCCACCATTTTATTTATTT
TTGGGATTTTGATAGGTTATTATGTACATACAAATTGCCCTTCAGATGCTCCATCTTCAGGAACAGTTGATCCTCAGTTATATCAAGAGA
TTCTCAAGACAATCCAGGCAGAAGATATTAAGAAGTCTTTCAGAAATTTGGTACAACTATATAAAAATGAAGATGACATGGAAATTTCAA
AGAAGATTAAGACTCAGTGGACCTCTTTGGGCCTAGAAGATGTACAGTTTGTAAATTACTCTGTGCTGCTTGATCTGCCAGGCCCTTCTC
CCAGCACTGTGACTCTGAGCAGCAGTGGTCAATGCTTTCATCCTAATGGCCAGCCTTGCAGTGAAGAAGCCAGAAAAGATAGCAGCCAAG
ACCTGCTCTATTCATATGCAGCCTATTCTGCCAAAGGAACTCTCAAGGCTGAAGTCATCGATGTGAGTTATGGAATGGCAGATGATTTAA
AAAGGATTAGGAAAATAAAAAACGTAACAAATCAGATCGCACTCCTGAAATTAGGAAAATTGCCACTGCTTTATAAGCTTTCCTCATTGG
AAAAGGCTGGATTTGGAGGTGTTCTTCTGTATATCGATCCTTGTGATTTGCCAAAGACTGTGAATCCTAGCCATGATACCTTCATGGTGT
CACTGAATCCAGGAGGAGACCCTTCTACGCCTGGTTACCCAAGTGTCGATGAAAGTTTTAGACAAAGCCGATCAAACCTCACCTCTCTAT
TAGTGCAGCCCATCTCTGCACCCCTCGTTGCAAAACTGATCTCTTCGCCAAAAGCTAGAACCAAAAATGAAGCGTGTAGCTCTCTAGAGC
TTCCAAATAATGAAATAAGAGTCGTCAGCATGCAAGTTCAGACAGTCACAAAATTGAAAACAGTTACTAATGTTGTTGGATTTGTAATGG
GCTTGACATCTCCAGACCGGTATATCATAGTTGGCAGCCATCATCACACTGCACACAGTTATAATGGACAAGAATGGGCCAGTAGTACTG
CAATAATCACAGCGTTTATCCGTGCCTTGATGTCAAAAGTTAAGAGAGGGTGGAGACCAGACCGAACTATTGTTTTCTGTTCTTGGGGAG
GAACAGCTTTTGGCAATATTGGCTCATATGAATGGGGAGAGGATTTCAAGAAGGTTCTTCAGAAAAATGTTGTGGCTTATATTAGCCTCC
ACAGTCCCATAAGGGGGAACTCTAGTCTGTATCCTGTAGCATCACCATCTCTTCAGCAACTGGTAGTAGAGAAAAATAATTTCAACTGTA
CCAGAAGAGCCCAGTGCCCAGAAACCAATATCAGTTCTATACAGATACAAGGTGATGCTGATTATTTCATCAACCATCTTGGAGTTCCCA
TCGTGCAGTTTGCTTACGAGGACATCAAAACATTAGAGGGTCCAAGTTTTCTCTCCGAGGCCCGTTTTTCTACACGAGCAACAAAAATTG
AAGAAATGGATCCCTCTTTCAACCTTCATGAAACCATTACTAAGATTCTGATTTTAGATGAAGCCACAGCTGCCATGGACACAGAGACAG
ACTTATTGATTCAAGAGACCATCCGAGAAGCATTTGCAGACTGTACCATGCTGACCATTGCCCATCGCCTGCACACGGTTCTAGGCTCCG
ATAGGATTATGGTGCTGGCCCAGGGACAGGTGGTGGAGTTTGACACCCCATCGGTCCTTCTGTCCAACGACAGTTCCCGATTCTATGCCA
TGTTTGCTGCTGCAGAGAACAAGGTCGCTGTCAAGGGCTGACTCCTCCCTGTTGACGAAGTCTCTTTTCTTTAGAGCATTGCCATTCCCT
GCCTGGGGCGGGCCCCTCATCGCGTCCTCCTACCGAAACCTTGCCTTTCTCGATTTTATCTTTCGCACAGCAGTTCCGGATTGGCTTGTG
TGTTTCACTTTTAGGGAGAGTCATATTTTGATTATTGTATTTATTCCATATTCATGTAAACAAAATTTAGTTTTTGTTCTTAATTGCACT
CTAAAAGGTTCAGGGAACCGTTATTATAATTGTATCAGAGGCCTATAATGAAGCTTTATACGTGTAGCTATATCTATATATAATTCTGTA
CATAGCCTATATTTACAGTGAAAATGTAAGCTGTTTATTTTATATTAAAATAAGCACTGTGCTAATAACAGTGCATATTCCTTTCTATCA
TTTTTGTACAGTTTGCTGTACTAGAGATCTGGTTTTGCTATTAGACTGTAGGAAGAGTAGCATTTCATTCTTCTCTAGCTGGTGGTTTCA
CGGTGCCAGGTTTTCTGGGTGTCCAAAGGAAGACGTGTGGCAATAGTGGGCCCTCCGACAGCCCCCTCTGCCGCCTCCCCACGGCCGCTC
CAGGGGTGGCTGGAGACGGGTGGGCGGCTGGAGACCATGCAGAGCGCCGTGAGTTCTCAGGGCTCCTGCCTTCTGTCCTGGTGTCACTTA
CTGTTTCTGTCAGGAGAGCAGCGGGGCGAAGCCCAGGCCCCTTTTCACTCCCTCCATCAAGAATGGGGATCACAGAGACATTCCTCCGAG
CCGGGGAGTTTCTTTCCTGCCTTCTTCTTTTTGCTGTTGTTTCTAAACAAGAATCAGTCTATCCACAGAGAGTCCCACTGCCTCAGGTTC
CTATGGCTGGCCACTGCACAGAGCTCTCCAGCTCCAAGACCTGTTGGTTCCAAGCCCTGGAGCCAACTGCTGCTTTTTGAGGTGGCACTT
TTTCATTTGCCTATTCCCACACCTCCACAGTTCAGTGGCAGGGCTCAGGATTTCGTGGGTCTGTTTTCCTTTCTCACCGCAGTCGTCGCA
CAGTCTCTCTCTCTCTCTCCCCTCAAAGTCTGCAACTTTAAGCAGCTCTTGCTAATCAGTGTCTCACACTGGCGTAGAAGTTTTTGTACT
GTAAAGAGACCTACCTCAGGTTGCTGGTTGCTGTGTGGTTTGGTGTGTTCCCGCAAACCCCCTTTGTGCTGTGGGGCTGGTAGCTCAGGT
GGGCGTGGTCACTGCTGTCATCAATTGAATGGTCAGCGTTGCATGTCGTGACCAACTAGACATTCTGTCGCCTTAGCATGTTTGCTGAAC

>57022_57022_4_NAALADL2-ABCC5_NAALADL2_chr3_175345174_ENST00000454872_ABCC5_chr3_183643507_ENST00000334444_length(amino acids)=720AA_BP=632
MGENEASLPNTSLQGKKMAYQKVHADQRAPGHSQYLDNDDLQATALDLEWDMEKELEESGFDQFQLDGAENQNLGHSETIDLNLDSIQPA
TSPKGRFQRLQEESDYITHYTRSAPKSNRCNFCHVLKILCTATILFIFGILIGYYVHTNCPSDAPSSGTVDPQLYQEILKTIQAEDIKKS
FRNLVQLYKNEDDMEISKKIKTQWTSLGLEDVQFVNYSVLLDLPGPSPSTVTLSSSGQCFHPNGQPCSEEARKDSSQDLLYSYAAYSAKG
TLKAEVIDVSYGMADDLKRIRKIKNVTNQIALLKLGKLPLLYKLSSLEKAGFGGVLLYIDPCDLPKTVNPSHDTFMVSLNPGGDPSTPGY
PSVDESFRQSRSNLTSLLVQPISAPLVAKLISSPKARTKNEACSSLELPNNEIRVVSMQVQTVTKLKTVTNVVGFVMGLTSPDRYIIVGS
HHHTAHSYNGQEWASSTAIITAFIRALMSKVKRGWRPDRTIVFCSWGGTAFGNIGSYEWGEDFKKVLQKNVVAYISLHSPIRGNSSLYPV
ASPSLQQLVVEKNNFNCTRRAQCPETNISSIQIQGDADYFINHLGVPIVQFAYEDIKTLEGPSFLSEARFSTRATKIEEMDPSFNLHETI
TKILILDEATAAMDTETDLLIQETIREAFADCTMLTIAHRLHTVLGSDRIMVLAQGQVVEFDTPSVLLSNDSSRFYAMFAAAENKVAVKG

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Fusion Gene PPI Analysis for NAALADL2-ABCC5


check button Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in

ChiPPI page.


check button Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160)
HgeneHgene's interactorsTgeneTgene's interactors


check button - Retained PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenStill interaction with


check button - Lost PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


check button - Retained PPIs, but lost function due to frame-shift fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


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Related Drugs for NAALADL2-ABCC5


check button Drugs targeting genes involved in this fusion gene.
(DrugBank Version 5.1.8 2021-05-08)
PartnerGeneUniProtAccDrugBank IDDrug nameDrug activityDrug typeDrug status

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Related Diseases for NAALADL2-ABCC5


check button Diseases associated with fusion partners.
(DisGeNet 4.0)
PartnerGeneDisease IDDisease name# pubmedsSource