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Center for Computational Systems Medicine
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Fusion Gene Summary

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Fusion Gene ORF analysis

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Fusion Genomic Features

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Fusion Protein Features

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Fusion Gene Sequence

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Fusion Gene PPI analysis

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Related Drugs

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Related Diseases

Fusion gene:NAALADL2-PEX5L (FusionGDB2 ID:57040)

Fusion Gene Summary for NAALADL2-PEX5L

check button Fusion gene summary
Fusion gene informationFusion gene name: NAALADL2-PEX5L
Fusion gene ID: 57040
HgeneTgene
Gene symbol

NAALADL2

PEX5L

Gene ID

254827

51555

Gene nameN-acetylated alpha-linked acidic dipeptidase like 2peroxisomal biogenesis factor 5 like
Synonyms-PEX5R|PEX5RP|PXR2|PXR2B|TRIP8b
Cytomap

3q26.31

3q26.33

Type of geneprotein-codingprotein-coding
Descriptioninactive N-acetylated-alpha-linked acidic dipeptidase-like protein 2N-acetylated alpha-linked acidic dipeptidase 2NAALADase L2glutamate carboxypeptidase II-type non-peptidase homologuePEX5-related proteinHCN channel auxiliary subunitPEX2-related proteinPEX5-like proteinPex5p-related proteinperoxin-5-related proteinperoxisome biogenesis factor 5-liketetratricopeptide repeat-containing Rab8b-interacting protein
Modification date2020031320200313
UniProtAcc..
Ensembl transtripts involved in fusion geneENST00000473253, ENST00000454872, 
ENST00000263962, ENST00000392649, 
ENST00000467460, ENST00000468741, 
ENST00000476138, ENST00000485199, 
ENST00000464614, ENST00000465751, 
ENST00000467440, ENST00000472994, 
Fusion gene scores* DoF score28 X 19 X 9=478811 X 12 X 6=792
# samples 2911
** MAII scorelog2(29/4788*10)=-4.04529834692857
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0
log2(11/792*10)=-2.84799690655495
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0
Context

PubMed: NAALADL2 [Title/Abstract] AND PEX5L [Title/Abstract] AND fusion [Title/Abstract]

Most frequent breakpointNAALADL2(175189546)-PEX5L(179537764), # samples:3
Anticipated loss of major functional domain due to fusion event.
* DoF score (Degree of Frequency) = # partners X # break points X # cancer types
** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)

check button Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez
PartnerGeneGO IDGO termPubMed ID

check buttonFusion gene breakpoints across NAALADL2 (5'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check buttonFusion gene breakpoints across PEX5L (3'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check button Fusion gene information from two resources (ChiTars 5.0 and ChimerDB 4.0)
* All genome coordinats were lifted-over on hg19.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
SourceDiseaseSampleHgeneHchrHbpHstrandTgeneTchrTbpTstrand
ChimerDB4BRCATCGA-AO-A0JM-01ANAALADL2chr3

175189546

-PEX5Lchr3

179537764

-
ChimerDB4BRCATCGA-AO-A0JM-01ANAALADL2chr3

175189546

+PEX5Lchr3

179537764

-


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Fusion Gene ORF analysis for NAALADL2-PEX5L

check button Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
ORFHenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrand
3UTR-3CDSENST00000473253ENST00000263962NAALADL2chr3

175189546

+PEX5Lchr3

179537764

-
3UTR-3CDSENST00000473253ENST00000392649NAALADL2chr3

175189546

+PEX5Lchr3

179537764

-
3UTR-3CDSENST00000473253ENST00000467460NAALADL2chr3

175189546

+PEX5Lchr3

179537764

-
3UTR-3CDSENST00000473253ENST00000468741NAALADL2chr3

175189546

+PEX5Lchr3

179537764

-
3UTR-3CDSENST00000473253ENST00000476138NAALADL2chr3

175189546

+PEX5Lchr3

179537764

-
3UTR-3CDSENST00000473253ENST00000485199NAALADL2chr3

175189546

+PEX5Lchr3

179537764

-
3UTR-5UTRENST00000473253ENST00000464614NAALADL2chr3

175189546

+PEX5Lchr3

179537764

-
3UTR-5UTRENST00000473253ENST00000465751NAALADL2chr3

175189546

+PEX5Lchr3

179537764

-
3UTR-5UTRENST00000473253ENST00000467440NAALADL2chr3

175189546

+PEX5Lchr3

179537764

-
3UTR-5UTRENST00000473253ENST00000472994NAALADL2chr3

175189546

+PEX5Lchr3

179537764

-
5CDS-5UTRENST00000454872ENST00000464614NAALADL2chr3

175189546

+PEX5Lchr3

179537764

-
5CDS-5UTRENST00000454872ENST00000465751NAALADL2chr3

175189546

+PEX5Lchr3

179537764

-
5CDS-5UTRENST00000454872ENST00000467440NAALADL2chr3

175189546

+PEX5Lchr3

179537764

-
5CDS-5UTRENST00000454872ENST00000472994NAALADL2chr3

175189546

+PEX5Lchr3

179537764

-
In-frameENST00000454872ENST00000263962NAALADL2chr3

175189546

+PEX5Lchr3

179537764

-
In-frameENST00000454872ENST00000392649NAALADL2chr3

175189546

+PEX5Lchr3

179537764

-
In-frameENST00000454872ENST00000467460NAALADL2chr3

175189546

+PEX5Lchr3

179537764

-
In-frameENST00000454872ENST00000468741NAALADL2chr3

175189546

+PEX5Lchr3

179537764

-
In-frameENST00000454872ENST00000476138NAALADL2chr3

175189546

+PEX5Lchr3

179537764

-
In-frameENST00000454872ENST00000485199NAALADL2chr3

175189546

+PEX5Lchr3

179537764

-

check buttonORFfinder result based on the fusion transcript sequence of in-frame fusion genes.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandSeq length
(transcript)
BP loci
(transcript)
Predicted start
(transcript)
Predicted stop
(transcript)
Seq length
(amino acids)
ENST00000454872NAALADL2chr3175189546+ENST00000467460PEX5Lchr3179537764-971017811282839903
ENST00000454872NAALADL2chr3175189546+ENST00000263962PEX5Lchr3179537764-361217811282839903
ENST00000454872NAALADL2chr3175189546+ENST00000392649PEX5Lchr3179537764-360217811282839903
ENST00000454872NAALADL2chr3175189546+ENST00000485199PEX5Lchr3179537764-360217811282839903
ENST00000454872NAALADL2chr3175189546+ENST00000468741PEX5Lchr3179537764-315017811282839903
ENST00000454872NAALADL2chr3175189546+ENST00000476138PEX5Lchr3179537764-314517811282839903

check buttonDeepORF prediction of the coding potential based on the fusion transcript sequence of in-frame fusion genes. DeepORF is a coding potential classifier based on convolutional neural network by comparing the real Ribo-seq data. If the no-coding score < 0.5 and coding score > 0.5, then the in-frame fusion transcript is predicted as being likely translated.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandNo-coding scoreCoding score
ENST00000454872ENST00000467460NAALADL2chr3175189546+PEX5Lchr3179537764-0.0001489490.999851
ENST00000454872ENST00000263962NAALADL2chr3175189546+PEX5Lchr3179537764-0.0008491950.99915075
ENST00000454872ENST00000392649NAALADL2chr3175189546+PEX5Lchr3179537764-0.0008562720.9991437
ENST00000454872ENST00000485199NAALADL2chr3175189546+PEX5Lchr3179537764-0.0008562720.9991437
ENST00000454872ENST00000468741NAALADL2chr3175189546+PEX5Lchr3179537764-0.0008853590.9991146
ENST00000454872ENST00000476138NAALADL2chr3175189546+PEX5Lchr3179537764-0.0009115820.9990884

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Fusion Genomic Features for NAALADL2-PEX5L


check buttonFusionAI prediction of the potential fusion gene breakpoint based on the pre-mature RNA sequence context (+/- 5kb of individual partner genes, total 20kb length sequence). FusionAI is a fusion gene breakpoint classifier based on convolutional neural network by comparing the fusion positive and negative sequence context of ~ 20K fusion gene data. From here, we can have the relative potentency of the 20K genomic sequence how individual sequnce will be likely used as the gene fusion breakpoints.
HgeneHchrHbpHstrandTgeneTchrTbpTstrand1-pp (fusion gene breakpoint)

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions. We integrated a total of 44 different types of human genomic feature loci information across five big categories including virus integration sites, repeats, structural variants, chromatin states, and gene expression regulation. More details are in help page.
genomic feature

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions that are ovelapped with the top 1% feature importance score regions. More details are in help page.

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Fusion Protein Features for NAALADL2-PEX5L


check button Four levels of functional features of fusion genes
Go to FGviewer search page for the most frequent breakpoint (https://ccsmweb.uth.edu/FGviewer/chr3:175189546/chr3:179537764)
- FGviewer provides the online visualization of the retention search of the protein functional features across DNA, RNA, protein, and pathological levels.
- How to search
1. Put your fusion gene symbol.
2. Press the tab key until there will be shown the breakpoint information filled.
4. Go down and press 'Search' tab twice.
4. Go down to have the hyperlink of the search result.
5. Click the hyperlink.
6. See the FGviewer result for your fusion gene.
FGviewer

check buttonMain function of each fusion partner protein. (from UniProt)
HgeneTgene
..
FUNCTION: Transcriptional activator which is required for calcium-dependent dendritic growth and branching in cortical neurons. Recruits CREB-binding protein (CREBBP) to nuclear bodies. Component of the CREST-BRG1 complex, a multiprotein complex that regulates promoter activation by orchestrating a calcium-dependent release of a repressor complex and a recruitment of an activator complex. In resting neurons, transcription of the c-FOS promoter is inhibited by BRG1-dependent recruitment of a phospho-RB1-HDAC1 repressor complex. Upon calcium influx, RB1 is dephosphorylated by calcineurin, which leads to release of the repressor complex. At the same time, there is increased recruitment of CREBBP to the promoter by a CREST-dependent mechanism, which leads to transcriptional activation. The CREST-BRG1 complex also binds to the NR2B promoter, and activity-dependent induction of NR2B expression involves a release of HDAC1 and recruitment of CREBBP (By similarity). {ECO:0000250}.FUNCTION: Transcriptional activator which is required for calcium-dependent dendritic growth and branching in cortical neurons. Recruits CREB-binding protein (CREBBP) to nuclear bodies. Component of the CREST-BRG1 complex, a multiprotein complex that regulates promoter activation by orchestrating a calcium-dependent release of a repressor complex and a recruitment of an activator complex. In resting neurons, transcription of the c-FOS promoter is inhibited by BRG1-dependent recruitment of a phospho-RB1-HDAC1 repressor complex. Upon calcium influx, RB1 is dephosphorylated by calcineurin, which leads to release of the repressor complex. At the same time, there is increased recruitment of CREBBP to the promoter by a CREST-dependent mechanism, which leads to transcriptional activation. The CREST-BRG1 complex also binds to the NR2B promoter, and activity-dependent induction of NR2B expression involves a release of HDAC1 and recruitment of CREBBP (By similarity). {ECO:0000250}.

check buttonRetention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at

download page


* Minus value of BPloci means that the break pointn is located before the CDS.
- In-frame and retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneNAALADL2chr3:175189546chr3:179537764ENST00000454872+9141_121551796.0Topological domainCytoplasmic
HgeneNAALADL2chr3:175189546chr3:179537764ENST00000454872+914122_142551796.0TransmembraneHelical%3B Signal-anchor for type II membrane protein
TgenePEX5Lchr3:175189546chr3:179537764ENST00000263962715326_359272625.0RepeatNote=TPR 1
TgenePEX5Lchr3:175189546chr3:179537764ENST00000263962715360_393272625.0RepeatNote=TPR 2
TgenePEX5Lchr3:175189546chr3:179537764ENST00000263962715395_427272625.0RepeatNote=TPR 3
TgenePEX5Lchr3:175189546chr3:179537764ENST00000263962715474_507272625.0RepeatNote=TPR 4
TgenePEX5Lchr3:175189546chr3:179537764ENST00000263962715509_541272625.0RepeatNote=TPR 5
TgenePEX5Lchr3:175189546chr3:179537764ENST00000263962715543_575272625.0RepeatNote=TPR 6
TgenePEX5Lchr3:175189546chr3:179537764ENST00000392649412326_359166519.0RepeatNote=TPR 1
TgenePEX5Lchr3:175189546chr3:179537764ENST00000392649412360_393166519.0RepeatNote=TPR 2
TgenePEX5Lchr3:175189546chr3:179537764ENST00000392649412395_427166519.0RepeatNote=TPR 3
TgenePEX5Lchr3:175189546chr3:179537764ENST00000392649412474_507166519.0RepeatNote=TPR 4
TgenePEX5Lchr3:175189546chr3:179537764ENST00000392649412509_541166519.0RepeatNote=TPR 5
TgenePEX5Lchr3:175189546chr3:179537764ENST00000392649412543_575166519.0RepeatNote=TPR 6
TgenePEX5Lchr3:175189546chr3:179537764ENST00000464614614326_359166519.0RepeatNote=TPR 1
TgenePEX5Lchr3:175189546chr3:179537764ENST00000464614614360_393166519.0RepeatNote=TPR 2
TgenePEX5Lchr3:175189546chr3:179537764ENST00000464614614395_427166519.0RepeatNote=TPR 3
TgenePEX5Lchr3:175189546chr3:179537764ENST00000464614614474_507166519.0RepeatNote=TPR 4
TgenePEX5Lchr3:175189546chr3:179537764ENST00000464614614509_541166519.0RepeatNote=TPR 5
TgenePEX5Lchr3:175189546chr3:179537764ENST00000464614614543_575166519.0RepeatNote=TPR 6
TgenePEX5Lchr3:175189546chr3:179537764ENST00000465751614326_359250603.0RepeatNote=TPR 1
TgenePEX5Lchr3:175189546chr3:179537764ENST00000465751614360_393250603.0RepeatNote=TPR 2
TgenePEX5Lchr3:175189546chr3:179537764ENST00000465751614395_427250603.0RepeatNote=TPR 3
TgenePEX5Lchr3:175189546chr3:179537764ENST00000465751614474_507250603.0RepeatNote=TPR 4
TgenePEX5Lchr3:175189546chr3:179537764ENST00000465751614509_541250603.0RepeatNote=TPR 5
TgenePEX5Lchr3:175189546chr3:179537764ENST00000465751614543_575250603.0RepeatNote=TPR 6
TgenePEX5Lchr3:175189546chr3:179537764ENST00000467460715326_359274627.0RepeatNote=TPR 1
TgenePEX5Lchr3:175189546chr3:179537764ENST00000467460715360_393274627.0RepeatNote=TPR 2
TgenePEX5Lchr3:175189546chr3:179537764ENST00000467460715395_427274627.0RepeatNote=TPR 3
TgenePEX5Lchr3:175189546chr3:179537764ENST00000467460715474_507274627.0RepeatNote=TPR 4
TgenePEX5Lchr3:175189546chr3:179537764ENST00000467460715509_541274627.0RepeatNote=TPR 5
TgenePEX5Lchr3:175189546chr3:179537764ENST00000467460715543_575274627.0RepeatNote=TPR 6
TgenePEX5Lchr3:175189546chr3:179537764ENST00000468741614326_35982435.0RepeatNote=TPR 1
TgenePEX5Lchr3:175189546chr3:179537764ENST00000468741614360_39382435.0RepeatNote=TPR 2
TgenePEX5Lchr3:175189546chr3:179537764ENST00000468741614395_42782435.0RepeatNote=TPR 3
TgenePEX5Lchr3:175189546chr3:179537764ENST00000468741614474_50782435.0RepeatNote=TPR 4
TgenePEX5Lchr3:175189546chr3:179537764ENST00000468741614509_54182435.0RepeatNote=TPR 5
TgenePEX5Lchr3:175189546chr3:179537764ENST00000468741614543_57582435.0RepeatNote=TPR 6
TgenePEX5Lchr3:175189546chr3:179537764ENST00000472994513326_359215568.0RepeatNote=TPR 1
TgenePEX5Lchr3:175189546chr3:179537764ENST00000472994513360_393215568.0RepeatNote=TPR 2
TgenePEX5Lchr3:175189546chr3:179537764ENST00000472994513395_427215568.0RepeatNote=TPR 3
TgenePEX5Lchr3:175189546chr3:179537764ENST00000472994513474_507215568.0RepeatNote=TPR 4
TgenePEX5Lchr3:175189546chr3:179537764ENST00000472994513509_541215568.0RepeatNote=TPR 5
TgenePEX5Lchr3:175189546chr3:179537764ENST00000472994513543_575215568.0RepeatNote=TPR 6
TgenePEX5Lchr3:175189546chr3:179537764ENST00000476138715326_359231584.0RepeatNote=TPR 1
TgenePEX5Lchr3:175189546chr3:179537764ENST00000476138715360_393231584.0RepeatNote=TPR 2
TgenePEX5Lchr3:175189546chr3:179537764ENST00000476138715395_427231584.0RepeatNote=TPR 3
TgenePEX5Lchr3:175189546chr3:179537764ENST00000476138715474_507231584.0RepeatNote=TPR 4
TgenePEX5Lchr3:175189546chr3:179537764ENST00000476138715509_541231584.0RepeatNote=TPR 5
TgenePEX5Lchr3:175189546chr3:179537764ENST00000476138715543_575231584.0RepeatNote=TPR 6
TgenePEX5Lchr3:175189546chr3:179537764ENST00000485199614326_359239592.0RepeatNote=TPR 1
TgenePEX5Lchr3:175189546chr3:179537764ENST00000485199614360_393239592.0RepeatNote=TPR 2
TgenePEX5Lchr3:175189546chr3:179537764ENST00000485199614395_427239592.0RepeatNote=TPR 3
TgenePEX5Lchr3:175189546chr3:179537764ENST00000485199614474_507239592.0RepeatNote=TPR 4
TgenePEX5Lchr3:175189546chr3:179537764ENST00000485199614509_541239592.0RepeatNote=TPR 5
TgenePEX5Lchr3:175189546chr3:179537764ENST00000485199614543_575239592.0RepeatNote=TPR 6

- In-frame and not-retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneNAALADL2chr3:175189546chr3:179537764ENST00000454872+914143_795551796.0Topological domainExtracellular


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Fusion Gene Sequence for NAALADL2-PEX5L


check button For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. To have fusion amino acid sequence, we ran ORFfinder and chose the longest ORF among the all predicted ones.
>57040_57040_1_NAALADL2-PEX5L_NAALADL2_chr3_175189546_ENST00000454872_PEX5L_chr3_179537764_ENST00000263962_length(transcript)=3612nt_BP=1781nt
TTATTCACAGAAGAAAGCAGGTAGTATACTGTTACAATACTACAGTAGAAAGTCAGAAGGTCACAAAGCTTGCAGGGTAAGTGACACAAC
TTGAAACTGCTTGGCCCTCTTTAAAAAGAAATAATAAAATGGGAGAGAATGAAGCAAGTTTACCTAACACGTCTTTGCAAGGTAAAAAGA
TGGCCTATCAGAAGGTCCATGCAGATCAAAGAGCTCCAGGACACTCACAGTACTTAGACAATGATGACCTTCAAGCCACTGCCCTTGACT
TAGAGTGGGACATGGAGAAGGAACTAGAGGAGTCTGGTTTTGACCAATTCCAGCTAGACGGTGCTGAGAATCAGAACCTAGGGCATTCAG
AGACTATAGACCTCAATCTTGATTCCATTCAACCAGCAACTTCACCCAAAGGAAGGTTCCAGAGACTTCAAGAAGAATCTGACTACATTA
CCCATTATACACGATCTGCACCAAAGAGCAATCGCTGCAACTTTTGCCACGTCTTAAAAATACTTTGCACAGCCACCATTTTATTTATTT
TTGGGATTTTGATAGGTTATTATGTACATACAAATTGCCCTTCAGATGCTCCATCTTCAGGAACAGTTGATCCTCAGTTATATCAAGAGA
TTCTCAAGACAATCCAGGCAGAAGATATTAAGAAGTCTTTCAGAAATTTGGTACAACTATATAAAAATGAAGATGACATGGAAATTTCAA
AGAAGATTAAGACTCAGTGGACCTCTTTGGGCCTAGAAGATGTACAGTTTGTAAATTACTCTGTGCTGCTTGATCTGCCAGGCCCTTCTC
CCAGCACTGTGACTCTGAGCAGCAGTGGTCAATGCTTTCATCCTAATGGCCAGCCTTGCAGTGAAGAAGCCAGAAAAGATAGCAGCCAAG
ACCTGCTCTATTCATATGCAGCCTATTCTGCCAAAGGAACTCTCAAGGCTGAAGTCATCGATGTGAGTTATGGAATGGCAGATGATTTAA
AAAGGATTAGGAAAATAAAAAACGTAACAAATCAGATCGCACTCCTGAAATTAGGAAAATTGCCACTGCTTTATAAGCTTTCCTCATTGG
AAAAGGCTGGATTTGGAGGTGTTCTTCTGTATATCGATCCTTGTGATTTGCCAAAGACTGTGAATCCTAGCCATGATACCTTCATGGTGT
CACTGAATCCAGGAGGAGACCCTTCTACGCCTGGTTACCCAAGTGTCGATGAAAGTTTTAGACAAAGCCGATCAAACCTCACCTCTCTAT
TAGTGCAGCCCATCTCTGCACCCCTCGTTGCAAAACTGATCTCTTCGCCAAAAGCTAGAACCAAAAATGAAGCGTGTAGCTCTCTAGAGC
TTCCAAATAATGAAATAAGAGTCGTCAGCATGCAAGTTCAGACAGTCACAAAATTGAAAACAGTTACTAATGTTGTTGGATTTGTAATGG
GCTTGACATCTCCAGACCGGTATATCATAGTTGGCAGCCATCATCACACTGCACACAGTTATAATGGACAAGAATGGGCCAGTAGTACTG
CAATAATCACAGCGTTTATCCGTGCCTTGATGTCAAAAGTTAAGAGAGGGTGGAGACCAGACCGAACTATTGTTTTCTGTTCTTGGGGAG
GAACAGCTTTTGGCAATATTGGCTCATATGAATGGGGAGAGGATTTCAAGAAGGTTCTTCAGAAAAATGTTGTGGCTTATATTAGCCTCC
ACAGTCCCATAAGGGGGAACTCTAGTCTGTATCCTGTAGCATCACCATCTCTTCAGCAACTGGTAGTAGAGTCAGATACAGAGTTTTGGG
ATAAGATGCAAGCAGAATGGGAAGAAATGGCTCGGAGGAACTGGATATCTGAGAACCAAGAAGCCCAGAACCAAGTAACCATCTCGGCTA
GTGAGAAGGGATATTACTTTCACACTGAAAACCCCTTCAAGGACTGGCCTGGAGCATTTGAAGAAGGCTTAAAAAGGCTGAAGGAAGGGG
ATCTGCCAGTCACCATCCTGTTCATGGAAGCAGCAATTCTTCAGGACCCTGGAGATGCAGAGGCATGGCAGTTCCTCGGGATAACCCAGG
CGGAGAATGAAAATGAACAAGCAGCTATTGTCGCCCTCCAGAGGTGCTTAGAATTACAGCCCAACAACTTAAAAGCTTTGATGGCCTTGG
CTGTGAGTTATACTAACACTGGCCATCAGCAGGATGCCTGTGACGCTCTGAAGAATTGGATTAAGCAAAATCCAAAGTACAAATACCTTG
TGAAAAGCAAGAAGGGATCTCCAGGCCTCACCCGGCGGATGTCTAAGTCCCCAGTTGATAGCTCTGTTCTGGAAGGGGTGAAGGAATTAT
ATCTGGAAGCTGCCCACCAAAATGGAGATATGATCGACCCAGACCTGCAGACAGGTCTAGGGGTTCTGTTCCACCTGAGTGGAGAATTTA
ATAGAGCAATAGATGCATTTAACGCTGCCTTAACTGTTCGGCCAGAGGACTATTCACTATGGAACCGCCTCGGGGCGACCTTGGCGAACG
GAGACCGCAGCGAGGAAGCCGTGGAGGCCTATACGCGAGCACTGGAGATTCAGCCAGGATTCATCCGGTCCAGATACAACCTAGGAATAA
GCTGCATCAACCTGGGCGCCTACAGAGAAGCGGTCAGCAATTTTCTCACTGCCCTCAGTTTGCAAAGAAAGAGCAGGAATCAGCAGCAAG
TTCCTCATCCTGCAATCTCTGGGAATATCTGGGCTGCCCTCAGAATTGCGCTCTCTCTGATGGACCAACCAGAACTCTTCCAGGCGGCTA
ATCTTGGTGACCTGGATGTCCTCTTAAGAGCTTTCAACTTGGATCCTTGAAGAAAGAATAATACCAGTACTAATAATCCCTGATCTGTGT
GATTGTACTGAAAAATCAAAAACTATTTTATTATGAATTTCAAAAGGATAAATCAAATATTCAAAAGGCCATGGTCATATAGCCCAAGGA
AATTAATTCCTGTGGACAATGCCCAGTCTCTGTTCAGATCCAAAAGCACAAAATGTTGTATATAGAGTCAAAGTCAGGCTCAAAAGAAGA
ATTAAGAGACTCAAGACAAACCAAGATAAAGTAACTGTGTGTTGAATACTCTTTCCACAAGTTGCAAGCATATTGCAACACATGTTCTTT
GGGTTTTTTGTCTCCCCTTGCAGCTGATGACACATCTGAGGAACTTGTTCATGGGAAACATGGAAAAAGCACTGCCTCAGATTGGGAAAT
TCTGACTGTTTCTGAACTGTCTTCTTTTGCAAGACTGAACATAGTTTGGGCCATTGGTGCATGCACATATATTAACTTGTGACTAAAGAC
AGACATTGCTTAAACCTGTTCCAATTTTAACTTTTACTGTAGCCCTTTGATTCCAGAGAGGGAGCTTTGCTGGCAAAAGCAGTTTTTGCA
CTAGAAATTTTTGCTGTTCCCAATCTAAACTTTTCTGGTATTGTATATATGCACTTTAATATCTTATTTATGCCTTGCTGGAGTTTTGTT
TTGTTGCTCCAATTTTTAACTTGGGGGTGAAAGATTTAAGAACTCAGCCTCACTAGATCAACGGACCAAATAAACAATTCCTGAAGACAG

>57040_57040_1_NAALADL2-PEX5L_NAALADL2_chr3_175189546_ENST00000454872_PEX5L_chr3_179537764_ENST00000263962_length(amino acids)=903AA_BP=551
MGENEASLPNTSLQGKKMAYQKVHADQRAPGHSQYLDNDDLQATALDLEWDMEKELEESGFDQFQLDGAENQNLGHSETIDLNLDSIQPA
TSPKGRFQRLQEESDYITHYTRSAPKSNRCNFCHVLKILCTATILFIFGILIGYYVHTNCPSDAPSSGTVDPQLYQEILKTIQAEDIKKS
FRNLVQLYKNEDDMEISKKIKTQWTSLGLEDVQFVNYSVLLDLPGPSPSTVTLSSSGQCFHPNGQPCSEEARKDSSQDLLYSYAAYSAKG
TLKAEVIDVSYGMADDLKRIRKIKNVTNQIALLKLGKLPLLYKLSSLEKAGFGGVLLYIDPCDLPKTVNPSHDTFMVSLNPGGDPSTPGY
PSVDESFRQSRSNLTSLLVQPISAPLVAKLISSPKARTKNEACSSLELPNNEIRVVSMQVQTVTKLKTVTNVVGFVMGLTSPDRYIIVGS
HHHTAHSYNGQEWASSTAIITAFIRALMSKVKRGWRPDRTIVFCSWGGTAFGNIGSYEWGEDFKKVLQKNVVAYISLHSPIRGNSSLYPV
ASPSLQQLVVESDTEFWDKMQAEWEEMARRNWISENQEAQNQVTISASEKGYYFHTENPFKDWPGAFEEGLKRLKEGDLPVTILFMEAAI
LQDPGDAEAWQFLGITQAENENEQAAIVALQRCLELQPNNLKALMALAVSYTNTGHQQDACDALKNWIKQNPKYKYLVKSKKGSPGLTRR
MSKSPVDSSVLEGVKELYLEAAHQNGDMIDPDLQTGLGVLFHLSGEFNRAIDAFNAALTVRPEDYSLWNRLGATLANGDRSEEAVEAYTR
ALEIQPGFIRSRYNLGISCINLGAYREAVSNFLTALSLQRKSRNQQQVPHPAISGNIWAALRIALSLMDQPELFQAANLGDLDVLLRAFN

--------------------------------------------------------------
>57040_57040_2_NAALADL2-PEX5L_NAALADL2_chr3_175189546_ENST00000454872_PEX5L_chr3_179537764_ENST00000392649_length(transcript)=3602nt_BP=1781nt
TTATTCACAGAAGAAAGCAGGTAGTATACTGTTACAATACTACAGTAGAAAGTCAGAAGGTCACAAAGCTTGCAGGGTAAGTGACACAAC
TTGAAACTGCTTGGCCCTCTTTAAAAAGAAATAATAAAATGGGAGAGAATGAAGCAAGTTTACCTAACACGTCTTTGCAAGGTAAAAAGA
TGGCCTATCAGAAGGTCCATGCAGATCAAAGAGCTCCAGGACACTCACAGTACTTAGACAATGATGACCTTCAAGCCACTGCCCTTGACT
TAGAGTGGGACATGGAGAAGGAACTAGAGGAGTCTGGTTTTGACCAATTCCAGCTAGACGGTGCTGAGAATCAGAACCTAGGGCATTCAG
AGACTATAGACCTCAATCTTGATTCCATTCAACCAGCAACTTCACCCAAAGGAAGGTTCCAGAGACTTCAAGAAGAATCTGACTACATTA
CCCATTATACACGATCTGCACCAAAGAGCAATCGCTGCAACTTTTGCCACGTCTTAAAAATACTTTGCACAGCCACCATTTTATTTATTT
TTGGGATTTTGATAGGTTATTATGTACATACAAATTGCCCTTCAGATGCTCCATCTTCAGGAACAGTTGATCCTCAGTTATATCAAGAGA
TTCTCAAGACAATCCAGGCAGAAGATATTAAGAAGTCTTTCAGAAATTTGGTACAACTATATAAAAATGAAGATGACATGGAAATTTCAA
AGAAGATTAAGACTCAGTGGACCTCTTTGGGCCTAGAAGATGTACAGTTTGTAAATTACTCTGTGCTGCTTGATCTGCCAGGCCCTTCTC
CCAGCACTGTGACTCTGAGCAGCAGTGGTCAATGCTTTCATCCTAATGGCCAGCCTTGCAGTGAAGAAGCCAGAAAAGATAGCAGCCAAG
ACCTGCTCTATTCATATGCAGCCTATTCTGCCAAAGGAACTCTCAAGGCTGAAGTCATCGATGTGAGTTATGGAATGGCAGATGATTTAA
AAAGGATTAGGAAAATAAAAAACGTAACAAATCAGATCGCACTCCTGAAATTAGGAAAATTGCCACTGCTTTATAAGCTTTCCTCATTGG
AAAAGGCTGGATTTGGAGGTGTTCTTCTGTATATCGATCCTTGTGATTTGCCAAAGACTGTGAATCCTAGCCATGATACCTTCATGGTGT
CACTGAATCCAGGAGGAGACCCTTCTACGCCTGGTTACCCAAGTGTCGATGAAAGTTTTAGACAAAGCCGATCAAACCTCACCTCTCTAT
TAGTGCAGCCCATCTCTGCACCCCTCGTTGCAAAACTGATCTCTTCGCCAAAAGCTAGAACCAAAAATGAAGCGTGTAGCTCTCTAGAGC
TTCCAAATAATGAAATAAGAGTCGTCAGCATGCAAGTTCAGACAGTCACAAAATTGAAAACAGTTACTAATGTTGTTGGATTTGTAATGG
GCTTGACATCTCCAGACCGGTATATCATAGTTGGCAGCCATCATCACACTGCACACAGTTATAATGGACAAGAATGGGCCAGTAGTACTG
CAATAATCACAGCGTTTATCCGTGCCTTGATGTCAAAAGTTAAGAGAGGGTGGAGACCAGACCGAACTATTGTTTTCTGTTCTTGGGGAG
GAACAGCTTTTGGCAATATTGGCTCATATGAATGGGGAGAGGATTTCAAGAAGGTTCTTCAGAAAAATGTTGTGGCTTATATTAGCCTCC
ACAGTCCCATAAGGGGGAACTCTAGTCTGTATCCTGTAGCATCACCATCTCTTCAGCAACTGGTAGTAGAGTCAGATACAGAGTTTTGGG
ATAAGATGCAAGCAGAATGGGAAGAAATGGCTCGGAGGAACTGGATATCTGAGAACCAAGAAGCCCAGAACCAAGTAACCATCTCGGCTA
GTGAGAAGGGATATTACTTTCACACTGAAAACCCCTTCAAGGACTGGCCTGGAGCATTTGAAGAAGGCTTAAAAAGGCTGAAGGAAGGGG
ATCTGCCAGTCACCATCCTGTTCATGGAAGCAGCAATTCTTCAGGACCCTGGAGATGCAGAGGCATGGCAGTTCCTCGGGATAACCCAGG
CGGAGAATGAAAATGAACAAGCAGCTATTGTCGCCCTCCAGAGGTGCTTAGAATTACAGCCCAACAACTTAAAAGCTTTGATGGCCTTGG
CTGTGAGTTATACTAACACTGGCCATCAGCAGGATGCCTGTGACGCTCTGAAGAATTGGATTAAGCAAAATCCAAAGTACAAATACCTTG
TGAAAAGCAAGAAGGGATCTCCAGGCCTCACCCGGCGGATGTCTAAGTCCCCAGTTGATAGCTCTGTTCTGGAAGGGGTGAAGGAATTAT
ATCTGGAAGCTGCCCACCAAAATGGAGATATGATCGACCCAGACCTGCAGACAGGTCTAGGGGTTCTGTTCCACCTGAGTGGAGAATTTA
ATAGAGCAATAGATGCATTTAACGCTGCCTTAACTGTTCGGCCAGAGGACTATTCACTATGGAACCGCCTCGGGGCGACCTTGGCGAACG
GAGACCGCAGCGAGGAAGCCGTGGAGGCCTATACGCGAGCACTGGAGATTCAGCCAGGATTCATCCGGTCCAGATACAACCTAGGAATAA
GCTGCATCAACCTGGGCGCCTACAGAGAAGCGGTCAGCAATTTTCTCACTGCCCTCAGTTTGCAAAGAAAGAGCAGGAATCAGCAGCAAG
TTCCTCATCCTGCAATCTCTGGGAATATCTGGGCTGCCCTCAGAATTGCGCTCTCTCTGATGGACCAACCAGAACTCTTCCAGGCGGCTA
ATCTTGGTGACCTGGATGTCCTCTTAAGAGCTTTCAACTTGGATCCTTGAAGAAAGAATAATACCAGTACTAATAATCCCTGATCTGTGT
GATTGTACTGAAAAATCAAAAACTATTTTATTATGAATTTCAAAAGGATAAATCAAATATTCAAAAGGCCATGGTCATATAGCCCAAGGA
AATTAATTCCTGTGGACAATGCCCAGTCTCTGTTCAGATCCAAAAGCACAAAATGTTGTATATAGAGTCAAAGTCAGGCTCAAAAGAAGA
ATTAAGAGACTCAAGACAAACCAAGATAAAGTAACTGTGTGTTGAATACTCTTTCCACAAGTTGCAAGCATATTGCAACACATGTTCTTT
GGGTTTTTTGTCTCCCCTTGCAGCTGATGACACATCTGAGGAACTTGTTCATGGGAAACATGGAAAAAGCACTGCCTCAGATTGGGAAAT
TCTGACTGTTTCTGAACTGTCTTCTTTTGCAAGACTGAACATAGTTTGGGCCATTGGTGCATGCACATATATTAACTTGTGACTAAAGAC
AGACATTGCTTAAACCTGTTCCAATTTTAACTTTTACTGTAGCCCTTTGATTCCAGAGAGGGAGCTTTGCTGGCAAAAGCAGTTTTTGCA
CTAGAAATTTTTGCTGTTCCCAATCTAAACTTTTCTGGTATTGTATATATGCACTTTAATATCTTATTTATGCCTTGCTGGAGTTTTGTT
TTGTTGCTCCAATTTTTAACTTGGGGGTGAAAGATTTAAGAACTCAGCCTCACTAGATCAACGGACCAAATAAACAATTCCTGAAGACAG

>57040_57040_2_NAALADL2-PEX5L_NAALADL2_chr3_175189546_ENST00000454872_PEX5L_chr3_179537764_ENST00000392649_length(amino acids)=903AA_BP=551
MGENEASLPNTSLQGKKMAYQKVHADQRAPGHSQYLDNDDLQATALDLEWDMEKELEESGFDQFQLDGAENQNLGHSETIDLNLDSIQPA
TSPKGRFQRLQEESDYITHYTRSAPKSNRCNFCHVLKILCTATILFIFGILIGYYVHTNCPSDAPSSGTVDPQLYQEILKTIQAEDIKKS
FRNLVQLYKNEDDMEISKKIKTQWTSLGLEDVQFVNYSVLLDLPGPSPSTVTLSSSGQCFHPNGQPCSEEARKDSSQDLLYSYAAYSAKG
TLKAEVIDVSYGMADDLKRIRKIKNVTNQIALLKLGKLPLLYKLSSLEKAGFGGVLLYIDPCDLPKTVNPSHDTFMVSLNPGGDPSTPGY
PSVDESFRQSRSNLTSLLVQPISAPLVAKLISSPKARTKNEACSSLELPNNEIRVVSMQVQTVTKLKTVTNVVGFVMGLTSPDRYIIVGS
HHHTAHSYNGQEWASSTAIITAFIRALMSKVKRGWRPDRTIVFCSWGGTAFGNIGSYEWGEDFKKVLQKNVVAYISLHSPIRGNSSLYPV
ASPSLQQLVVESDTEFWDKMQAEWEEMARRNWISENQEAQNQVTISASEKGYYFHTENPFKDWPGAFEEGLKRLKEGDLPVTILFMEAAI
LQDPGDAEAWQFLGITQAENENEQAAIVALQRCLELQPNNLKALMALAVSYTNTGHQQDACDALKNWIKQNPKYKYLVKSKKGSPGLTRR
MSKSPVDSSVLEGVKELYLEAAHQNGDMIDPDLQTGLGVLFHLSGEFNRAIDAFNAALTVRPEDYSLWNRLGATLANGDRSEEAVEAYTR
ALEIQPGFIRSRYNLGISCINLGAYREAVSNFLTALSLQRKSRNQQQVPHPAISGNIWAALRIALSLMDQPELFQAANLGDLDVLLRAFN

--------------------------------------------------------------
>57040_57040_3_NAALADL2-PEX5L_NAALADL2_chr3_175189546_ENST00000454872_PEX5L_chr3_179537764_ENST00000467460_length(transcript)=9710nt_BP=1781nt
TTATTCACAGAAGAAAGCAGGTAGTATACTGTTACAATACTACAGTAGAAAGTCAGAAGGTCACAAAGCTTGCAGGGTAAGTGACACAAC
TTGAAACTGCTTGGCCCTCTTTAAAAAGAAATAATAAAATGGGAGAGAATGAAGCAAGTTTACCTAACACGTCTTTGCAAGGTAAAAAGA
TGGCCTATCAGAAGGTCCATGCAGATCAAAGAGCTCCAGGACACTCACAGTACTTAGACAATGATGACCTTCAAGCCACTGCCCTTGACT
TAGAGTGGGACATGGAGAAGGAACTAGAGGAGTCTGGTTTTGACCAATTCCAGCTAGACGGTGCTGAGAATCAGAACCTAGGGCATTCAG
AGACTATAGACCTCAATCTTGATTCCATTCAACCAGCAACTTCACCCAAAGGAAGGTTCCAGAGACTTCAAGAAGAATCTGACTACATTA
CCCATTATACACGATCTGCACCAAAGAGCAATCGCTGCAACTTTTGCCACGTCTTAAAAATACTTTGCACAGCCACCATTTTATTTATTT
TTGGGATTTTGATAGGTTATTATGTACATACAAATTGCCCTTCAGATGCTCCATCTTCAGGAACAGTTGATCCTCAGTTATATCAAGAGA
TTCTCAAGACAATCCAGGCAGAAGATATTAAGAAGTCTTTCAGAAATTTGGTACAACTATATAAAAATGAAGATGACATGGAAATTTCAA
AGAAGATTAAGACTCAGTGGACCTCTTTGGGCCTAGAAGATGTACAGTTTGTAAATTACTCTGTGCTGCTTGATCTGCCAGGCCCTTCTC
CCAGCACTGTGACTCTGAGCAGCAGTGGTCAATGCTTTCATCCTAATGGCCAGCCTTGCAGTGAAGAAGCCAGAAAAGATAGCAGCCAAG
ACCTGCTCTATTCATATGCAGCCTATTCTGCCAAAGGAACTCTCAAGGCTGAAGTCATCGATGTGAGTTATGGAATGGCAGATGATTTAA
AAAGGATTAGGAAAATAAAAAACGTAACAAATCAGATCGCACTCCTGAAATTAGGAAAATTGCCACTGCTTTATAAGCTTTCCTCATTGG
AAAAGGCTGGATTTGGAGGTGTTCTTCTGTATATCGATCCTTGTGATTTGCCAAAGACTGTGAATCCTAGCCATGATACCTTCATGGTGT
CACTGAATCCAGGAGGAGACCCTTCTACGCCTGGTTACCCAAGTGTCGATGAAAGTTTTAGACAAAGCCGATCAAACCTCACCTCTCTAT
TAGTGCAGCCCATCTCTGCACCCCTCGTTGCAAAACTGATCTCTTCGCCAAAAGCTAGAACCAAAAATGAAGCGTGTAGCTCTCTAGAGC
TTCCAAATAATGAAATAAGAGTCGTCAGCATGCAAGTTCAGACAGTCACAAAATTGAAAACAGTTACTAATGTTGTTGGATTTGTAATGG
GCTTGACATCTCCAGACCGGTATATCATAGTTGGCAGCCATCATCACACTGCACACAGTTATAATGGACAAGAATGGGCCAGTAGTACTG
CAATAATCACAGCGTTTATCCGTGCCTTGATGTCAAAAGTTAAGAGAGGGTGGAGACCAGACCGAACTATTGTTTTCTGTTCTTGGGGAG
GAACAGCTTTTGGCAATATTGGCTCATATGAATGGGGAGAGGATTTCAAGAAGGTTCTTCAGAAAAATGTTGTGGCTTATATTAGCCTCC
ACAGTCCCATAAGGGGGAACTCTAGTCTGTATCCTGTAGCATCACCATCTCTTCAGCAACTGGTAGTAGAGTCAGATACAGAGTTTTGGG
ATAAGATGCAAGCAGAATGGGAAGAAATGGCTCGGAGGAACTGGATATCTGAGAACCAAGAAGCCCAGAACCAAGTAACCATCTCGGCTA
GTGAGAAGGGATATTACTTTCACACTGAAAACCCCTTCAAGGACTGGCCTGGAGCATTTGAAGAAGGCTTAAAAAGGCTGAAGGAAGGGG
ATCTGCCAGTCACCATCCTGTTCATGGAAGCAGCAATTCTTCAGGACCCTGGAGATGCAGAGGCATGGCAGTTCCTCGGGATAACCCAGG
CGGAGAATGAAAATGAACAAGCAGCTATTGTCGCCCTCCAGAGGTGCTTAGAATTACAGCCCAACAACTTAAAAGCTTTGATGGCCTTGG
CTGTGAGTTATACTAACACTGGCCATCAGCAGGATGCCTGTGACGCTCTGAAGAATTGGATTAAGCAAAATCCAAAGTACAAATACCTTG
TGAAAAGCAAGAAGGGATCTCCAGGCCTCACCCGGCGGATGTCTAAGTCCCCAGTTGATAGCTCTGTTCTGGAAGGGGTGAAGGAATTAT
ATCTGGAAGCTGCCCACCAAAATGGAGATATGATCGACCCAGACCTGCAGACAGGTCTAGGGGTTCTGTTCCACCTGAGTGGAGAATTTA
ATAGAGCAATAGATGCATTTAACGCTGCCTTAACTGTTCGGCCAGAGGACTATTCACTATGGAACCGCCTCGGGGCGACCTTGGCGAACG
GAGACCGCAGCGAGGAAGCCGTGGAGGCCTATACGCGAGCACTGGAGATTCAGCCAGGATTCATCCGGTCCAGATACAACCTAGGAATAA
GCTGCATCAACCTGGGCGCCTACAGAGAAGCGGTCAGCAATTTTCTCACTGCCCTCAGTTTGCAAAGAAAGAGCAGGAATCAGCAGCAAG
TTCCTCATCCTGCAATCTCTGGGAATATCTGGGCTGCCCTCAGAATTGCGCTCTCTCTGATGGACCAACCAGAACTCTTCCAGGCGGCTA
ATCTTGGTGACCTGGATGTCCTCTTAAGAGCTTTCAACTTGGATCCTTGAAGAAAGAATAATACCAGTACTAATAATCCCTGATCTGTGT
GATTGTACTGAAAAATCAAAAACTATTTTATTATGAATTTCAAAAGGATAAATCAAATATTCAAAAGGCCATGGTCATATAGCCCAAGGA
AATTAATTCCTGTGGACAATGCCCAGTCTCTGTTCAGATCCAAAAGCACAAAATGTTGTATATAGAGTCAAAGTCAGGCTCAAAAGAAGA
ATTAAGAGACTCAAGACAAACCAAGATAAAGTAACTGTGTGTTGAATACTCTTTCCACAAGTTGCAAGCATATTGCAACACATGTTCTTT
GGGTTTTTTGTCTCCCCTTGCAGCTGATGACACATCTGAGGAACTTGTTCATGGGAAACATGGAAAAAGCACTGCCTCAGATTGGGAAAT
TCTGACTGTTTCTGAACTGTCTTCTTTTGCAAGACTGAACATAGTTTGGGCCATTGGTGCATGCACATATATTAACTTGTGACTAAAGAC
AGACATTGCTTAAACCTGTTCCAATTTTAACTTTTACTGTAGCCCTTTGATTCCAGAGAGGGAGCTTTGCTGGCAAAAGCAGTTTTTGCA
CTAGAAATTTTTGCTGTTCCCAATCTAAACTTTTCTGGTATTGTATATATGCACTTTAATATCTTATTTATGCCTTGCTGGAGTTTTGTT
TTGTTGCTCCAATTTTTAACTTGGGGGTGAAAGATTTAAGAACTCAGCCTCACTAGATCAACGGACCAAATAAACAATTCCTGAAGACAG
TTTTTCATAGTGTAGGATTTTGAAGAAGTGTTTTTCTTAAAGCAGATACGATGACATAAGGCGTAAATATGGCAAACAGATCTTTTCATT
CACGTGCTTTCTGGGTCTGTATGAACATAAGTAAGACACAAGGTACTGTCTCTTCATGCATTCTCTGCAGGAAGAAAGTTTGATGGTATC
GTGATTTCTATTGAGTTCAAATTAACTTGCTTAAGTGTCATACTTTACTGGCTTTGCCCTGCACACCAATATTCCTTTTAAACCATAAAT
ATTTTAAATAATATTTCTTAAGAGTGATAAATAACATTTTTTCCTAAAAATTATGTTTTCTTAGTTTCATAATAATCTGCACTGTTCATC
CCCTTGCATTCTAAGTGATAGAAGAGCAACACTTTCAAACCAAATCTCACTGAATGCCAGTGATTTCATATGAAAGATGCATGCCTCTTT
GGCTCTTTGAACATTTAGCAAGTATTGGGAATTTTCTATTAGCAGTGGTGTTTTAATTGGTTGAATTCCACTTAGTTCTCCACAGTGTTT
TGTATGTGTTTGGGGCTTGGTGATTATTTTGAAAGATACATTTTTTAAAGAATTAGGAACATTTTTTGCAAAATGCTAATCAGAATATAA
TTTTCCCAATGTCAGGTATAGAAGTTATCCCATTCTTCTTTACCTGGTCTCCTTCCTTCGTCTAGAACCTTCCCCACAGTAGCTAATCCT
AACAACTTTTTATTTATGTTCTTTGATAATAATAGCTCATCCCGCTCATGATTATAGCTACCCACAAAAAATAAAACAACAACAACAAAA
AAGACTCCACAGAATTGGGATCAAAACAGTCTAATTGGCTGGGGAATAAGCTTCTACTGAGGAGTAAATGTGCACACGTGCTTATCAATT
GAATGCGAGGTACAGGAATAAAATCCTCTCCTCTGTTACATCTGAAGTCCTTGGGTTGTGAGAGGGCCTCAAGTTAACAGAAACCACAAG
TCCTTGAGGCTTACATATGTTATAACCTATTCTAGTTTATAAAGACAAAAAGCTGAGGCCACTGTGAGGAGTGCCAGGTTTTGATAGTCA
TTGTCAAAGTTGACTTGGGCCAGGTGGTAGCTCCAGCTGGTCAGCAGAAGGCAGAGGCATTCAGGCACTCATCATGGGTAGCAGCGACCA
CCCAGTCTCAGACCGTGCTTCTCTACAGTCTCAGCAGCAAAGTAAAGCTCAACAATGCTTTCAAGAATGGTATTGTAAGAATTGTAGAAT
TCGAGAAACCCAGTCTGGTAAGGACTCTTGGGGCCAGCCTCCAAGCCATGGCAGGGCCTGCTTGAATATGCCTGATTAAGCATCCTTTCC
TTCCCTGCTCCTTCCTCCTGCCATCTCTGTACCTTGACCAGAAAGTCGGCATGAATAGTTCATGGACAAAGGATTGAATAGCCTCTGAAC
AAAGGATTCAAAGCAAACTTTGTAAGTGTTCTGTGATGCCATTCTATACTTTGAGCAGCAGCTGAATCTGCAGCCTGGATTTAAAGCCTG
AAACTAGTATAAATGTCAAATAATTAATTTGTTGCTAAATGGTGGCAAATTTTGTGGCCCAAGTTTTATTTTGCTATTGGAACACAAACT
CCAAGGAGCTGTTTTAGGGAAGACTAAACAATCTTCCATTCTTACCATTATTTGGCAATTTGCAGAGCATTTAGTAGTACTTTCTCTAGT
GTATGTAGTATCTGTCAGATCTAAGATTTTTATAGGCTGTCAAGAAGTCCAGAATTACGGCCCAAGAGGAAAAGAGTTGCATTTTTCAAT
AATATTTTTTATAAAATTAAGTTAAAACCATTATTAAAACATGAGTGACAGGCCAGGTGCGGTGGCTCACGCCTGTAATCCTAGCACTTT
GGGAGGCAGAGGCGGGCAGACCACGAGGTCAGGAGTTCGAGACCAGCCTGACCAACATGGTGAAACCCCGTCTTTATTAAGAATACAAAA
ATTAGCCGGGTGTAGTGGTATGCACCTGTAATACCAGCTACTCAGGAGGCTGAGGCAGGAGAATCACTTGAACCAGGGAGGCGGAGGTTG
CAGTGAGCCGAGATTGCACCGCTGCACTCCAGTCTGGGTGACAGAGCGAGACTCCGTCTCAAAAAAAACAAAAAAGTGACAGTTTATAGG
AATAGAGCACCACCAAGAAATCAGTAGCAAGACTTTAGAACAGTCTTTTTGTATAAATCATATACAGTAAATGTTTTGTTTCTTAGAAGT
GCATCTACTTTATTTTTTGGCAGAACAATTTTTGGCATCTTATCTTCATGGCATGAAATTGTCATTTAAATTACTCTTTCCGTTTGAAAG
GGGAGGGTATCCTTATTTCCCTTCTGAGGTACTCTGAGAAGGCTTTGAGTTTCCTTTTTCATGTATTAATGTATAACAGCCTAACAGCTC
CTAGAAGAGGGTATTCTTACTAGAATGGCTACATACGGGTGACTTCAGTTACATACAGGTGACTTCCAGGGACTGACTTCGCCTGTAGAT
TGGATGAAAATAAAGAGAAAGCCAGTGATTATTGCTGAGTTTCAAAATATAACCATTTCTAGTAGGCTACTTCTACATGCTGTTGTACCT
TCCTGGTGAGGAGGAGACAGAGGGATAGGGGAGAGGAGGAGGAATAAAAATCCCTCTCACTGGGCCAATCATACTGATTCATTCCCTTTA
CTTCCTCCAAAACTCACTCCCCATGACTCCTGAAAAATGGGTAGATCTCGTCCACCAGGAAATTTTAATAGAATACTATGCACCGTGCTT
TCTCAGTCAATCTGGATTCCTACTAGAACAGAAAAGTAAGGAAACATAACTGGGTAGGAATGTCCACTTACGTTTCACAAACTCACTTTT
AGAGTTTCATGCCACTTTCCTCATTCTTCTCTTTAAGATACTATTATATTGAACGTGGGACCCATGTCTAAATACTTGTATAGATAAATA
TTTCTTGTATATTCTTCCCATACAAGCAAGACTTGAATACAGTTGTAGCTAGTCCCACTTTTATAATAAAAGCTTCCAAACTCTTTATCA
TAAACTTTGTCTGTGAGCTTGGGAATACAGAGAAAGCAAGTTGATCATTCTGAGACCCTTCCTCATTTGCCCTGAATCAGTTCCCCAAGA
TTGGACTGTACTTTAAGCTAGTTGTTGTAGCAGTGGTGGTTGTTGTTTTATATCTTGAGATACTTCTAGAACATTCTAGAAACAGGGTAT
TCTAAAGGCTTACTTTATATGCCATCCTTTTTGAACCCTCTTATTTTAGAAATTATTACACGTGCACACTTATGATTTCAACCTTGTAAA
ATAATTTCAAATTCATTTCGTATCCACATTTTACTGCAGTTTCCCTATCATCATCTCAATAGTTATAGAACTGGTTGAAATTAAACTGTT
TTGAACTAAGAAGTAGATATATATATATATATATATATATATTTTTTTTTTTTTTTTTAAAGAGTGTTCATAGATAAACTCTGGCATAAA
GTTTGTAAAAAAGCAATTTTTTAAAAGCAAAACGTATAACCTCAGGTACAAAAATATTGCATGCATTAGTATTGCAAATTTGCCTACTCA
AATATTAACCAAAGCATGCAAGATAACTTGACTGAATTTAAATTTACACAGTGCATGATTAAGTCTCATAGGTTAGCCTGTTGTTCCTTG
CCTCTATACAAGGGAGCATTTTTATGAACTTTGTGTTACAGTTTTTCTATTTGCTTTTCTTATCCTATCCTTGAGATTGTTTTCATGCTA
TCACACTGAACTTTACAGATATTCACACATCTGGTTTCTACAGTGTTACCAGTGCCAAACTAATCCTCTGAAGAATCTGGGACATCTAAA
CACTTTTTCAAAAACCAGTTGAGGCACAACAGATCCCAAACTTAAACAAATCCAAGTGTCTGAATGCTACTAAACTAAATCATGTTGACT
GCCTCAGCACATAAAGGTTTCGACTTTAAATTCTTAATAATGCATTTCAAAATTTTTCTAAAAGTTTGGGAATAAATTAGAAAAACTGAT
ATTCTAAATAAGGCGAGGAGGTTGGGGTAATGTCAGGCACATCAAAATCATCACACAACGAAGTAGATATGGGGCCTTAATTTTCATAAA
TGTCACATAGCAAGTGTGTGGGGTATCACAACATTGTTCTGATACAGCCCTGTTTGTATGGTAGTTGAGCTGCTTGGGCTAAATGTCCCT
TGAGAAACTGGACTTGATCAACAGGTCTAAAAACACTGATATTTAGGGAGTGATGAGGTGATTTCACGGTCACTCAGAACCAACTCTGAA
ATCTTCTCACTGCCTTTTCCCATAACCCCTATTTTATGAGGAGACCAGAAAGGGAGAGAGCAAAGCTCAGTGAGACCATGTGGTCTTACA
TTAGTAACAGCTTTGTTACTCACTCCATATACCCCGGTACCCTCACACACATACCATGAACTCAAAGACAGAATTCTACACATAACACAC
ATAGCAAAGACGATTGTGGGGAGGCATTAAACAGTTAAGAGGAAAAAAAAAAACACAGAAAATTAAACTGTGAGGTTTAACAACCTCTCA
TGTGGTATTTTGCCTTGAACGAAGTTTCCACTACCTGCAGCTTCTGCAGAAATACCAAAATAACACAGTCTAGAGACAAGTGTCCCAATG
TCAGAACTGTTTTCTCAGGACCTTCTCTATAAGAGAAAACTAACTTGCAATGCTGCAGAATGTCAGAGCAAAACCCTGATGAGCTCCGTG
GGATACTTAATAGAAGCCTGCACTCAAAATAATATTAAGATGGAAACAACAACAACAATTAGGCAGTTCTTTGCTCAACTATAAAATGTG
TATCATTCATTGGGGGAGGGGGAGGGGTCGTGTTCTTTGGATTTCTTGGAAAGGGAAATGGTATAACACAAAAAGACTAAGAGGTATACA
CACTCAGCTCGGTAATTCGAGCATTTGGCATTTTCACTGAGATATATAGCATTTCTGCATGGATACCATACAAGAATTCTGCCATGTGAG
AAATGTGTTCATGATGGACTACATTACCAGTAGTTAAGGGAAATACAGCAAACTTAAGTTTTTACCAACTTCCTTTCATGTTCCCTATAT
ATCATCTAACCCAAACTTTCAATTTACATTGCCCAAATTTGTTTACATTGGTTGAAAAAAAACTGATTAATTTATTAAACTTTTTACAAA
CTGTAACAAACATTTAACTATTTAGAAAAGACATTTCTACATATTTTATATATCTATGAATATTGCATCTCTAATCTAATCTAAAAATGT
TGTTTTGAGACAATTCTTCTGTGATGCTTCCTCCTCATGCTCATAAATGTTTAAAGTCTTGGGATTTCATTTTCAGGCTGAAATAGATAA
CAAGAAAAAAATTTAAGTTTAAATGTTTACATTGCGTTACTAAATTAATACCAATTCAAATTAAGTGACCTATAGTAAATTAATGGCAAT
GGGGGGGAGGGGATTTTAAAGTGATTGGCATATTATGTGATACTGTATCAGTGATTTAGTGAAATAATATGTATCATAGCACAACTCTGT
TGGGTATTAAGGCTTCATCTTAGTATTTCCCTGCGTTGCTCTTTGAAATAAAATTACTACCATAAAAATAACCTCTTATCATATTGATGT
GTTTAATTTACTCAGTTGGCTTCTAATTTGCGTAACAAGATTAAGGTAGTATTTTTGTACTATTATTGGAAGCATGCCTTCCCTTTTTCA
CATTATTAAATTGTATTTATATTTGTGCAATTTTAAACTATGTTTTCAAATAAACTTTGTCTGCGGCTTCGAGGTCTTTTCAGGAATCTT
TCAAAATGGGATTTGGGGATCAGAACTCCTTCTGATCAAATGGAATCCAATTTGTACTACTGGCTAAAGGTCCTTTTATTAAATATTGAA
TATCACTACATATGATTTTGCATGAGCTATCTGGAAATCAGGAATGCATTTTTGGATATAAAACAAAACTTTAAAAATCTTCCTCCTTTG

>57040_57040_3_NAALADL2-PEX5L_NAALADL2_chr3_175189546_ENST00000454872_PEX5L_chr3_179537764_ENST00000467460_length(amino acids)=903AA_BP=551
MGENEASLPNTSLQGKKMAYQKVHADQRAPGHSQYLDNDDLQATALDLEWDMEKELEESGFDQFQLDGAENQNLGHSETIDLNLDSIQPA
TSPKGRFQRLQEESDYITHYTRSAPKSNRCNFCHVLKILCTATILFIFGILIGYYVHTNCPSDAPSSGTVDPQLYQEILKTIQAEDIKKS
FRNLVQLYKNEDDMEISKKIKTQWTSLGLEDVQFVNYSVLLDLPGPSPSTVTLSSSGQCFHPNGQPCSEEARKDSSQDLLYSYAAYSAKG
TLKAEVIDVSYGMADDLKRIRKIKNVTNQIALLKLGKLPLLYKLSSLEKAGFGGVLLYIDPCDLPKTVNPSHDTFMVSLNPGGDPSTPGY
PSVDESFRQSRSNLTSLLVQPISAPLVAKLISSPKARTKNEACSSLELPNNEIRVVSMQVQTVTKLKTVTNVVGFVMGLTSPDRYIIVGS
HHHTAHSYNGQEWASSTAIITAFIRALMSKVKRGWRPDRTIVFCSWGGTAFGNIGSYEWGEDFKKVLQKNVVAYISLHSPIRGNSSLYPV
ASPSLQQLVVESDTEFWDKMQAEWEEMARRNWISENQEAQNQVTISASEKGYYFHTENPFKDWPGAFEEGLKRLKEGDLPVTILFMEAAI
LQDPGDAEAWQFLGITQAENENEQAAIVALQRCLELQPNNLKALMALAVSYTNTGHQQDACDALKNWIKQNPKYKYLVKSKKGSPGLTRR
MSKSPVDSSVLEGVKELYLEAAHQNGDMIDPDLQTGLGVLFHLSGEFNRAIDAFNAALTVRPEDYSLWNRLGATLANGDRSEEAVEAYTR
ALEIQPGFIRSRYNLGISCINLGAYREAVSNFLTALSLQRKSRNQQQVPHPAISGNIWAALRIALSLMDQPELFQAANLGDLDVLLRAFN

--------------------------------------------------------------
>57040_57040_4_NAALADL2-PEX5L_NAALADL2_chr3_175189546_ENST00000454872_PEX5L_chr3_179537764_ENST00000468741_length(transcript)=3150nt_BP=1781nt
TTATTCACAGAAGAAAGCAGGTAGTATACTGTTACAATACTACAGTAGAAAGTCAGAAGGTCACAAAGCTTGCAGGGTAAGTGACACAAC
TTGAAACTGCTTGGCCCTCTTTAAAAAGAAATAATAAAATGGGAGAGAATGAAGCAAGTTTACCTAACACGTCTTTGCAAGGTAAAAAGA
TGGCCTATCAGAAGGTCCATGCAGATCAAAGAGCTCCAGGACACTCACAGTACTTAGACAATGATGACCTTCAAGCCACTGCCCTTGACT
TAGAGTGGGACATGGAGAAGGAACTAGAGGAGTCTGGTTTTGACCAATTCCAGCTAGACGGTGCTGAGAATCAGAACCTAGGGCATTCAG
AGACTATAGACCTCAATCTTGATTCCATTCAACCAGCAACTTCACCCAAAGGAAGGTTCCAGAGACTTCAAGAAGAATCTGACTACATTA
CCCATTATACACGATCTGCACCAAAGAGCAATCGCTGCAACTTTTGCCACGTCTTAAAAATACTTTGCACAGCCACCATTTTATTTATTT
TTGGGATTTTGATAGGTTATTATGTACATACAAATTGCCCTTCAGATGCTCCATCTTCAGGAACAGTTGATCCTCAGTTATATCAAGAGA
TTCTCAAGACAATCCAGGCAGAAGATATTAAGAAGTCTTTCAGAAATTTGGTACAACTATATAAAAATGAAGATGACATGGAAATTTCAA
AGAAGATTAAGACTCAGTGGACCTCTTTGGGCCTAGAAGATGTACAGTTTGTAAATTACTCTGTGCTGCTTGATCTGCCAGGCCCTTCTC
CCAGCACTGTGACTCTGAGCAGCAGTGGTCAATGCTTTCATCCTAATGGCCAGCCTTGCAGTGAAGAAGCCAGAAAAGATAGCAGCCAAG
ACCTGCTCTATTCATATGCAGCCTATTCTGCCAAAGGAACTCTCAAGGCTGAAGTCATCGATGTGAGTTATGGAATGGCAGATGATTTAA
AAAGGATTAGGAAAATAAAAAACGTAACAAATCAGATCGCACTCCTGAAATTAGGAAAATTGCCACTGCTTTATAAGCTTTCCTCATTGG
AAAAGGCTGGATTTGGAGGTGTTCTTCTGTATATCGATCCTTGTGATTTGCCAAAGACTGTGAATCCTAGCCATGATACCTTCATGGTGT
CACTGAATCCAGGAGGAGACCCTTCTACGCCTGGTTACCCAAGTGTCGATGAAAGTTTTAGACAAAGCCGATCAAACCTCACCTCTCTAT
TAGTGCAGCCCATCTCTGCACCCCTCGTTGCAAAACTGATCTCTTCGCCAAAAGCTAGAACCAAAAATGAAGCGTGTAGCTCTCTAGAGC
TTCCAAATAATGAAATAAGAGTCGTCAGCATGCAAGTTCAGACAGTCACAAAATTGAAAACAGTTACTAATGTTGTTGGATTTGTAATGG
GCTTGACATCTCCAGACCGGTATATCATAGTTGGCAGCCATCATCACACTGCACACAGTTATAATGGACAAGAATGGGCCAGTAGTACTG
CAATAATCACAGCGTTTATCCGTGCCTTGATGTCAAAAGTTAAGAGAGGGTGGAGACCAGACCGAACTATTGTTTTCTGTTCTTGGGGAG
GAACAGCTTTTGGCAATATTGGCTCATATGAATGGGGAGAGGATTTCAAGAAGGTTCTTCAGAAAAATGTTGTGGCTTATATTAGCCTCC
ACAGTCCCATAAGGGGGAACTCTAGTCTGTATCCTGTAGCATCACCATCTCTTCAGCAACTGGTAGTAGAGTCAGATACAGAGTTTTGGG
ATAAGATGCAAGCAGAATGGGAAGAAATGGCTCGGAGGAACTGGATATCTGAGAACCAAGAAGCCCAGAACCAAGTAACCATCTCGGCTA
GTGAGAAGGGATATTACTTTCACACTGAAAACCCCTTCAAGGACTGGCCTGGAGCATTTGAAGAAGGCTTAAAAAGGCTGAAGGAAGGGG
ATCTGCCAGTCACCATCCTGTTCATGGAAGCAGCAATTCTTCAGGACCCTGGAGATGCAGAGGCATGGCAGTTCCTCGGGATAACCCAGG
CGGAGAATGAAAATGAACAAGCAGCTATTGTCGCCCTCCAGAGGTGCTTAGAATTACAGCCCAACAACTTAAAAGCTTTGATGGCCTTGG
CTGTGAGTTATACTAACACTGGCCATCAGCAGGATGCCTGTGACGCTCTGAAGAATTGGATTAAGCAAAATCCAAAGTACAAATACCTTG
TGAAAAGCAAGAAGGGATCTCCAGGCCTCACCCGGCGGATGTCTAAGTCCCCAGTTGATAGCTCTGTTCTGGAAGGGGTGAAGGAATTAT
ATCTGGAAGCTGCCCACCAAAATGGAGATATGATCGACCCAGACCTGCAGACAGGTCTAGGGGTTCTGTTCCACCTGAGTGGAGAATTTA
ATAGAGCAATAGATGCATTTAACGCTGCCTTAACTGTTCGGCCAGAGGACTATTCACTATGGAACCGCCTCGGGGCGACCTTGGCGAACG
GAGACCGCAGCGAGGAAGCCGTGGAGGCCTATACGCGAGCACTGGAGATTCAGCCAGGATTCATCCGGTCCAGATACAACCTAGGAATAA
GCTGCATCAACCTGGGCGCCTACAGAGAAGCGGTCAGCAATTTTCTCACTGCCCTCAGTTTGCAAAGAAAGAGCAGGAATCAGCAGCAAG
TTCCTCATCCTGCAATCTCTGGGAATATCTGGGCTGCCCTCAGAATTGCGCTCTCTCTGATGGACCAACCAGAACTCTTCCAGGCGGCTA
ATCTTGGTGACCTGGATGTCCTCTTAAGAGCTTTCAACTTGGATCCTTGAAGAAAGAATAATACCAGTACTAATAATCCCTGATCTGTGT
GATTGTACTGAAAAATCAAAAACTATTTTATTATGAATTTCAAAAGGATAAATCAAATATTCAAAAGGCCATGGTCATATAGCCCAAGGA
AATTAATTCCTGTGGACAATGCCCAGTCTCTGTTCAGATCCAAAAGCACAAAATGTTGTATATAGAGTCAAAGTCAGGCTCAAAAGAAGA
ATTAAGAGACTCAAGACAAACCAAGATAAAGTAACTGTGTGTTGAATACTCTTTCCACAAGTTGCAAGCATATTGCAACACATGTTCTTT

>57040_57040_4_NAALADL2-PEX5L_NAALADL2_chr3_175189546_ENST00000454872_PEX5L_chr3_179537764_ENST00000468741_length(amino acids)=903AA_BP=551
MGENEASLPNTSLQGKKMAYQKVHADQRAPGHSQYLDNDDLQATALDLEWDMEKELEESGFDQFQLDGAENQNLGHSETIDLNLDSIQPA
TSPKGRFQRLQEESDYITHYTRSAPKSNRCNFCHVLKILCTATILFIFGILIGYYVHTNCPSDAPSSGTVDPQLYQEILKTIQAEDIKKS
FRNLVQLYKNEDDMEISKKIKTQWTSLGLEDVQFVNYSVLLDLPGPSPSTVTLSSSGQCFHPNGQPCSEEARKDSSQDLLYSYAAYSAKG
TLKAEVIDVSYGMADDLKRIRKIKNVTNQIALLKLGKLPLLYKLSSLEKAGFGGVLLYIDPCDLPKTVNPSHDTFMVSLNPGGDPSTPGY
PSVDESFRQSRSNLTSLLVQPISAPLVAKLISSPKARTKNEACSSLELPNNEIRVVSMQVQTVTKLKTVTNVVGFVMGLTSPDRYIIVGS
HHHTAHSYNGQEWASSTAIITAFIRALMSKVKRGWRPDRTIVFCSWGGTAFGNIGSYEWGEDFKKVLQKNVVAYISLHSPIRGNSSLYPV
ASPSLQQLVVESDTEFWDKMQAEWEEMARRNWISENQEAQNQVTISASEKGYYFHTENPFKDWPGAFEEGLKRLKEGDLPVTILFMEAAI
LQDPGDAEAWQFLGITQAENENEQAAIVALQRCLELQPNNLKALMALAVSYTNTGHQQDACDALKNWIKQNPKYKYLVKSKKGSPGLTRR
MSKSPVDSSVLEGVKELYLEAAHQNGDMIDPDLQTGLGVLFHLSGEFNRAIDAFNAALTVRPEDYSLWNRLGATLANGDRSEEAVEAYTR
ALEIQPGFIRSRYNLGISCINLGAYREAVSNFLTALSLQRKSRNQQQVPHPAISGNIWAALRIALSLMDQPELFQAANLGDLDVLLRAFN

--------------------------------------------------------------
>57040_57040_5_NAALADL2-PEX5L_NAALADL2_chr3_175189546_ENST00000454872_PEX5L_chr3_179537764_ENST00000476138_length(transcript)=3145nt_BP=1781nt
TTATTCACAGAAGAAAGCAGGTAGTATACTGTTACAATACTACAGTAGAAAGTCAGAAGGTCACAAAGCTTGCAGGGTAAGTGACACAAC
TTGAAACTGCTTGGCCCTCTTTAAAAAGAAATAATAAAATGGGAGAGAATGAAGCAAGTTTACCTAACACGTCTTTGCAAGGTAAAAAGA
TGGCCTATCAGAAGGTCCATGCAGATCAAAGAGCTCCAGGACACTCACAGTACTTAGACAATGATGACCTTCAAGCCACTGCCCTTGACT
TAGAGTGGGACATGGAGAAGGAACTAGAGGAGTCTGGTTTTGACCAATTCCAGCTAGACGGTGCTGAGAATCAGAACCTAGGGCATTCAG
AGACTATAGACCTCAATCTTGATTCCATTCAACCAGCAACTTCACCCAAAGGAAGGTTCCAGAGACTTCAAGAAGAATCTGACTACATTA
CCCATTATACACGATCTGCACCAAAGAGCAATCGCTGCAACTTTTGCCACGTCTTAAAAATACTTTGCACAGCCACCATTTTATTTATTT
TTGGGATTTTGATAGGTTATTATGTACATACAAATTGCCCTTCAGATGCTCCATCTTCAGGAACAGTTGATCCTCAGTTATATCAAGAGA
TTCTCAAGACAATCCAGGCAGAAGATATTAAGAAGTCTTTCAGAAATTTGGTACAACTATATAAAAATGAAGATGACATGGAAATTTCAA
AGAAGATTAAGACTCAGTGGACCTCTTTGGGCCTAGAAGATGTACAGTTTGTAAATTACTCTGTGCTGCTTGATCTGCCAGGCCCTTCTC
CCAGCACTGTGACTCTGAGCAGCAGTGGTCAATGCTTTCATCCTAATGGCCAGCCTTGCAGTGAAGAAGCCAGAAAAGATAGCAGCCAAG
ACCTGCTCTATTCATATGCAGCCTATTCTGCCAAAGGAACTCTCAAGGCTGAAGTCATCGATGTGAGTTATGGAATGGCAGATGATTTAA
AAAGGATTAGGAAAATAAAAAACGTAACAAATCAGATCGCACTCCTGAAATTAGGAAAATTGCCACTGCTTTATAAGCTTTCCTCATTGG
AAAAGGCTGGATTTGGAGGTGTTCTTCTGTATATCGATCCTTGTGATTTGCCAAAGACTGTGAATCCTAGCCATGATACCTTCATGGTGT
CACTGAATCCAGGAGGAGACCCTTCTACGCCTGGTTACCCAAGTGTCGATGAAAGTTTTAGACAAAGCCGATCAAACCTCACCTCTCTAT
TAGTGCAGCCCATCTCTGCACCCCTCGTTGCAAAACTGATCTCTTCGCCAAAAGCTAGAACCAAAAATGAAGCGTGTAGCTCTCTAGAGC
TTCCAAATAATGAAATAAGAGTCGTCAGCATGCAAGTTCAGACAGTCACAAAATTGAAAACAGTTACTAATGTTGTTGGATTTGTAATGG
GCTTGACATCTCCAGACCGGTATATCATAGTTGGCAGCCATCATCACACTGCACACAGTTATAATGGACAAGAATGGGCCAGTAGTACTG
CAATAATCACAGCGTTTATCCGTGCCTTGATGTCAAAAGTTAAGAGAGGGTGGAGACCAGACCGAACTATTGTTTTCTGTTCTTGGGGAG
GAACAGCTTTTGGCAATATTGGCTCATATGAATGGGGAGAGGATTTCAAGAAGGTTCTTCAGAAAAATGTTGTGGCTTATATTAGCCTCC
ACAGTCCCATAAGGGGGAACTCTAGTCTGTATCCTGTAGCATCACCATCTCTTCAGCAACTGGTAGTAGAGTCAGATACAGAGTTTTGGG
ATAAGATGCAAGCAGAATGGGAAGAAATGGCTCGGAGGAACTGGATATCTGAGAACCAAGAAGCCCAGAACCAAGTAACCATCTCGGCTA
GTGAGAAGGGATATTACTTTCACACTGAAAACCCCTTCAAGGACTGGCCTGGAGCATTTGAAGAAGGCTTAAAAAGGCTGAAGGAAGGGG
ATCTGCCAGTCACCATCCTGTTCATGGAAGCAGCAATTCTTCAGGACCCTGGAGATGCAGAGGCATGGCAGTTCCTCGGGATAACCCAGG
CGGAGAATGAAAATGAACAAGCAGCTATTGTCGCCCTCCAGAGGTGCTTAGAATTACAGCCCAACAACTTAAAAGCTTTGATGGCCTTGG
CTGTGAGTTATACTAACACTGGCCATCAGCAGGATGCCTGTGACGCTCTGAAGAATTGGATTAAGCAAAATCCAAAGTACAAATACCTTG
TGAAAAGCAAGAAGGGATCTCCAGGCCTCACCCGGCGGATGTCTAAGTCCCCAGTTGATAGCTCTGTTCTGGAAGGGGTGAAGGAATTAT
ATCTGGAAGCTGCCCACCAAAATGGAGATATGATCGACCCAGACCTGCAGACAGGTCTAGGGGTTCTGTTCCACCTGAGTGGAGAATTTA
ATAGAGCAATAGATGCATTTAACGCTGCCTTAACTGTTCGGCCAGAGGACTATTCACTATGGAACCGCCTCGGGGCGACCTTGGCGAACG
GAGACCGCAGCGAGGAAGCCGTGGAGGCCTATACGCGAGCACTGGAGATTCAGCCAGGATTCATCCGGTCCAGATACAACCTAGGAATAA
GCTGCATCAACCTGGGCGCCTACAGAGAAGCGGTCAGCAATTTTCTCACTGCCCTCAGTTTGCAAAGAAAGAGCAGGAATCAGCAGCAAG
TTCCTCATCCTGCAATCTCTGGGAATATCTGGGCTGCCCTCAGAATTGCGCTCTCTCTGATGGACCAACCAGAACTCTTCCAGGCGGCTA
ATCTTGGTGACCTGGATGTCCTCTTAAGAGCTTTCAACTTGGATCCTTGAAGAAAGAATAATACCAGTACTAATAATCCCTGATCTGTGT
GATTGTACTGAAAAATCAAAAACTATTTTATTATGAATTTCAAAAGGATAAATCAAATATTCAAAAGGCCATGGTCATATAGCCCAAGGA
AATTAATTCCTGTGGACAATGCCCAGTCTCTGTTCAGATCCAAAAGCACAAAATGTTGTATATAGAGTCAAAGTCAGGCTCAAAAGAAGA

>57040_57040_5_NAALADL2-PEX5L_NAALADL2_chr3_175189546_ENST00000454872_PEX5L_chr3_179537764_ENST00000476138_length(amino acids)=903AA_BP=551
MGENEASLPNTSLQGKKMAYQKVHADQRAPGHSQYLDNDDLQATALDLEWDMEKELEESGFDQFQLDGAENQNLGHSETIDLNLDSIQPA
TSPKGRFQRLQEESDYITHYTRSAPKSNRCNFCHVLKILCTATILFIFGILIGYYVHTNCPSDAPSSGTVDPQLYQEILKTIQAEDIKKS
FRNLVQLYKNEDDMEISKKIKTQWTSLGLEDVQFVNYSVLLDLPGPSPSTVTLSSSGQCFHPNGQPCSEEARKDSSQDLLYSYAAYSAKG
TLKAEVIDVSYGMADDLKRIRKIKNVTNQIALLKLGKLPLLYKLSSLEKAGFGGVLLYIDPCDLPKTVNPSHDTFMVSLNPGGDPSTPGY
PSVDESFRQSRSNLTSLLVQPISAPLVAKLISSPKARTKNEACSSLELPNNEIRVVSMQVQTVTKLKTVTNVVGFVMGLTSPDRYIIVGS
HHHTAHSYNGQEWASSTAIITAFIRALMSKVKRGWRPDRTIVFCSWGGTAFGNIGSYEWGEDFKKVLQKNVVAYISLHSPIRGNSSLYPV
ASPSLQQLVVESDTEFWDKMQAEWEEMARRNWISENQEAQNQVTISASEKGYYFHTENPFKDWPGAFEEGLKRLKEGDLPVTILFMEAAI
LQDPGDAEAWQFLGITQAENENEQAAIVALQRCLELQPNNLKALMALAVSYTNTGHQQDACDALKNWIKQNPKYKYLVKSKKGSPGLTRR
MSKSPVDSSVLEGVKELYLEAAHQNGDMIDPDLQTGLGVLFHLSGEFNRAIDAFNAALTVRPEDYSLWNRLGATLANGDRSEEAVEAYTR
ALEIQPGFIRSRYNLGISCINLGAYREAVSNFLTALSLQRKSRNQQQVPHPAISGNIWAALRIALSLMDQPELFQAANLGDLDVLLRAFN

--------------------------------------------------------------
>57040_57040_6_NAALADL2-PEX5L_NAALADL2_chr3_175189546_ENST00000454872_PEX5L_chr3_179537764_ENST00000485199_length(transcript)=3602nt_BP=1781nt
TTATTCACAGAAGAAAGCAGGTAGTATACTGTTACAATACTACAGTAGAAAGTCAGAAGGTCACAAAGCTTGCAGGGTAAGTGACACAAC
TTGAAACTGCTTGGCCCTCTTTAAAAAGAAATAATAAAATGGGAGAGAATGAAGCAAGTTTACCTAACACGTCTTTGCAAGGTAAAAAGA
TGGCCTATCAGAAGGTCCATGCAGATCAAAGAGCTCCAGGACACTCACAGTACTTAGACAATGATGACCTTCAAGCCACTGCCCTTGACT
TAGAGTGGGACATGGAGAAGGAACTAGAGGAGTCTGGTTTTGACCAATTCCAGCTAGACGGTGCTGAGAATCAGAACCTAGGGCATTCAG
AGACTATAGACCTCAATCTTGATTCCATTCAACCAGCAACTTCACCCAAAGGAAGGTTCCAGAGACTTCAAGAAGAATCTGACTACATTA
CCCATTATACACGATCTGCACCAAAGAGCAATCGCTGCAACTTTTGCCACGTCTTAAAAATACTTTGCACAGCCACCATTTTATTTATTT
TTGGGATTTTGATAGGTTATTATGTACATACAAATTGCCCTTCAGATGCTCCATCTTCAGGAACAGTTGATCCTCAGTTATATCAAGAGA
TTCTCAAGACAATCCAGGCAGAAGATATTAAGAAGTCTTTCAGAAATTTGGTACAACTATATAAAAATGAAGATGACATGGAAATTTCAA
AGAAGATTAAGACTCAGTGGACCTCTTTGGGCCTAGAAGATGTACAGTTTGTAAATTACTCTGTGCTGCTTGATCTGCCAGGCCCTTCTC
CCAGCACTGTGACTCTGAGCAGCAGTGGTCAATGCTTTCATCCTAATGGCCAGCCTTGCAGTGAAGAAGCCAGAAAAGATAGCAGCCAAG
ACCTGCTCTATTCATATGCAGCCTATTCTGCCAAAGGAACTCTCAAGGCTGAAGTCATCGATGTGAGTTATGGAATGGCAGATGATTTAA
AAAGGATTAGGAAAATAAAAAACGTAACAAATCAGATCGCACTCCTGAAATTAGGAAAATTGCCACTGCTTTATAAGCTTTCCTCATTGG
AAAAGGCTGGATTTGGAGGTGTTCTTCTGTATATCGATCCTTGTGATTTGCCAAAGACTGTGAATCCTAGCCATGATACCTTCATGGTGT
CACTGAATCCAGGAGGAGACCCTTCTACGCCTGGTTACCCAAGTGTCGATGAAAGTTTTAGACAAAGCCGATCAAACCTCACCTCTCTAT
TAGTGCAGCCCATCTCTGCACCCCTCGTTGCAAAACTGATCTCTTCGCCAAAAGCTAGAACCAAAAATGAAGCGTGTAGCTCTCTAGAGC
TTCCAAATAATGAAATAAGAGTCGTCAGCATGCAAGTTCAGACAGTCACAAAATTGAAAACAGTTACTAATGTTGTTGGATTTGTAATGG
GCTTGACATCTCCAGACCGGTATATCATAGTTGGCAGCCATCATCACACTGCACACAGTTATAATGGACAAGAATGGGCCAGTAGTACTG
CAATAATCACAGCGTTTATCCGTGCCTTGATGTCAAAAGTTAAGAGAGGGTGGAGACCAGACCGAACTATTGTTTTCTGTTCTTGGGGAG
GAACAGCTTTTGGCAATATTGGCTCATATGAATGGGGAGAGGATTTCAAGAAGGTTCTTCAGAAAAATGTTGTGGCTTATATTAGCCTCC
ACAGTCCCATAAGGGGGAACTCTAGTCTGTATCCTGTAGCATCACCATCTCTTCAGCAACTGGTAGTAGAGTCAGATACAGAGTTTTGGG
ATAAGATGCAAGCAGAATGGGAAGAAATGGCTCGGAGGAACTGGATATCTGAGAACCAAGAAGCCCAGAACCAAGTAACCATCTCGGCTA
GTGAGAAGGGATATTACTTTCACACTGAAAACCCCTTCAAGGACTGGCCTGGAGCATTTGAAGAAGGCTTAAAAAGGCTGAAGGAAGGGG
ATCTGCCAGTCACCATCCTGTTCATGGAAGCAGCAATTCTTCAGGACCCTGGAGATGCAGAGGCATGGCAGTTCCTCGGGATAACCCAGG
CGGAGAATGAAAATGAACAAGCAGCTATTGTCGCCCTCCAGAGGTGCTTAGAATTACAGCCCAACAACTTAAAAGCTTTGATGGCCTTGG
CTGTGAGTTATACTAACACTGGCCATCAGCAGGATGCCTGTGACGCTCTGAAGAATTGGATTAAGCAAAATCCAAAGTACAAATACCTTG
TGAAAAGCAAGAAGGGATCTCCAGGCCTCACCCGGCGGATGTCTAAGTCCCCAGTTGATAGCTCTGTTCTGGAAGGGGTGAAGGAATTAT
ATCTGGAAGCTGCCCACCAAAATGGAGATATGATCGACCCAGACCTGCAGACAGGTCTAGGGGTTCTGTTCCACCTGAGTGGAGAATTTA
ATAGAGCAATAGATGCATTTAACGCTGCCTTAACTGTTCGGCCAGAGGACTATTCACTATGGAACCGCCTCGGGGCGACCTTGGCGAACG
GAGACCGCAGCGAGGAAGCCGTGGAGGCCTATACGCGAGCACTGGAGATTCAGCCAGGATTCATCCGGTCCAGATACAACCTAGGAATAA
GCTGCATCAACCTGGGCGCCTACAGAGAAGCGGTCAGCAATTTTCTCACTGCCCTCAGTTTGCAAAGAAAGAGCAGGAATCAGCAGCAAG
TTCCTCATCCTGCAATCTCTGGGAATATCTGGGCTGCCCTCAGAATTGCGCTCTCTCTGATGGACCAACCAGAACTCTTCCAGGCGGCTA
ATCTTGGTGACCTGGATGTCCTCTTAAGAGCTTTCAACTTGGATCCTTGAAGAAAGAATAATACCAGTACTAATAATCCCTGATCTGTGT
GATTGTACTGAAAAATCAAAAACTATTTTATTATGAATTTCAAAAGGATAAATCAAATATTCAAAAGGCCATGGTCATATAGCCCAAGGA
AATTAATTCCTGTGGACAATGCCCAGTCTCTGTTCAGATCCAAAAGCACAAAATGTTGTATATAGAGTCAAAGTCAGGCTCAAAAGAAGA
ATTAAGAGACTCAAGACAAACCAAGATAAAGTAACTGTGTGTTGAATACTCTTTCCACAAGTTGCAAGCATATTGCAACACATGTTCTTT
GGGTTTTTTGTCTCCCCTTGCAGCTGATGACACATCTGAGGAACTTGTTCATGGGAAACATGGAAAAAGCACTGCCTCAGATTGGGAAAT
TCTGACTGTTTCTGAACTGTCTTCTTTTGCAAGACTGAACATAGTTTGGGCCATTGGTGCATGCACATATATTAACTTGTGACTAAAGAC
AGACATTGCTTAAACCTGTTCCAATTTTAACTTTTACTGTAGCCCTTTGATTCCAGAGAGGGAGCTTTGCTGGCAAAAGCAGTTTTTGCA
CTAGAAATTTTTGCTGTTCCCAATCTAAACTTTTCTGGTATTGTATATATGCACTTTAATATCTTATTTATGCCTTGCTGGAGTTTTGTT
TTGTTGCTCCAATTTTTAACTTGGGGGTGAAAGATTTAAGAACTCAGCCTCACTAGATCAACGGACCAAATAAACAATTCCTGAAGACAG

>57040_57040_6_NAALADL2-PEX5L_NAALADL2_chr3_175189546_ENST00000454872_PEX5L_chr3_179537764_ENST00000485199_length(amino acids)=903AA_BP=551
MGENEASLPNTSLQGKKMAYQKVHADQRAPGHSQYLDNDDLQATALDLEWDMEKELEESGFDQFQLDGAENQNLGHSETIDLNLDSIQPA
TSPKGRFQRLQEESDYITHYTRSAPKSNRCNFCHVLKILCTATILFIFGILIGYYVHTNCPSDAPSSGTVDPQLYQEILKTIQAEDIKKS
FRNLVQLYKNEDDMEISKKIKTQWTSLGLEDVQFVNYSVLLDLPGPSPSTVTLSSSGQCFHPNGQPCSEEARKDSSQDLLYSYAAYSAKG
TLKAEVIDVSYGMADDLKRIRKIKNVTNQIALLKLGKLPLLYKLSSLEKAGFGGVLLYIDPCDLPKTVNPSHDTFMVSLNPGGDPSTPGY
PSVDESFRQSRSNLTSLLVQPISAPLVAKLISSPKARTKNEACSSLELPNNEIRVVSMQVQTVTKLKTVTNVVGFVMGLTSPDRYIIVGS
HHHTAHSYNGQEWASSTAIITAFIRALMSKVKRGWRPDRTIVFCSWGGTAFGNIGSYEWGEDFKKVLQKNVVAYISLHSPIRGNSSLYPV
ASPSLQQLVVESDTEFWDKMQAEWEEMARRNWISENQEAQNQVTISASEKGYYFHTENPFKDWPGAFEEGLKRLKEGDLPVTILFMEAAI
LQDPGDAEAWQFLGITQAENENEQAAIVALQRCLELQPNNLKALMALAVSYTNTGHQQDACDALKNWIKQNPKYKYLVKSKKGSPGLTRR
MSKSPVDSSVLEGVKELYLEAAHQNGDMIDPDLQTGLGVLFHLSGEFNRAIDAFNAALTVRPEDYSLWNRLGATLANGDRSEEAVEAYTR
ALEIQPGFIRSRYNLGISCINLGAYREAVSNFLTALSLQRKSRNQQQVPHPAISGNIWAALRIALSLMDQPELFQAANLGDLDVLLRAFN

--------------------------------------------------------------

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Fusion Gene PPI Analysis for NAALADL2-PEX5L


check button Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in

ChiPPI page.


check button Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160)
HgeneHgene's interactorsTgeneTgene's interactors


check button - Retained PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenStill interaction with


check button - Lost PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


check button - Retained PPIs, but lost function due to frame-shift fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


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Related Drugs for NAALADL2-PEX5L


check button Drugs targeting genes involved in this fusion gene.
(DrugBank Version 5.1.8 2021-05-08)
PartnerGeneUniProtAccDrugBank IDDrug nameDrug activityDrug typeDrug status

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Related Diseases for NAALADL2-PEX5L


check button Diseases associated with fusion partners.
(DisGeNet 4.0)
PartnerGeneDisease IDDisease name# pubmedsSource