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Center for Computational Systems Medicine
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Fusion Gene Summary

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Fusion Gene ORF analysis

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Fusion Genomic Features

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Fusion Protein Features

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Fusion Gene Sequence

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Fusion Gene PPI analysis

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Related Drugs

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Related Diseases

Fusion gene:NACC2-NTRK2 (FusionGDB2 ID:57095)

Fusion Gene Summary for NACC2-NTRK2

check button Fusion gene summary
Fusion gene informationFusion gene name: NACC2-NTRK2
Fusion gene ID: 57095
HgeneTgene
Gene symbol

NACC2

NTRK2

Gene ID

138151

4915

Gene nameNACC family member 2neurotrophic receptor tyrosine kinase 2
SynonymsBEND9|BTBD14|BTBD14A|BTBD31|NAC-2|RBBEIEE58|GP145-TrkB|OBHD|TRKB|trk-B
Cytomap

9q34.3

9q21.33

Type of geneprotein-codingprotein-coding
Descriptionnucleus accumbens-associated protein 2BEN domain containing 9BTB (POZ) domain containing 14ABTB/POZ domain-containing protein 14ANACC family member 2, BEN and BTB (POZ) domain containingrepressor with BTB domain and BEN domaintranscription repressorBDNF/NT-3 growth factors receptorBDNF-tropomyosine receptor kinase Bneurotrophic tyrosine kinase receptor type 2tropomyosin-related kinase Btyrosine kinase receptor B
Modification date2020031320200313
UniProtAcc

Q96BF6

Q16620

Ensembl transtripts involved in fusion geneENST00000371753, ENST00000277554, 
ENST00000467669, 		ENST00000277120, 
ENST00000304053, ENST00000323115, 
ENST00000359847, ENST00000376208, 
ENST00000376213, ENST00000376214, 
ENST00000395866, ENST00000395882, 
Fusion gene scores* DoF score4 X 4 X 4=6410 X 9 X 7=630
# samples 510
** MAII scorelog2(5/64*10)=-0.356143810225275
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0		log2(10/630*10)=-2.65535182861255
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0
Context

PubMed: NACC2 [Title/Abstract] AND NTRK2 [Title/Abstract] AND fusion [Title/Abstract]

Most frequent breakpoint
Anticipated loss of major functional domain due to fusion event.NACC2-NTRK2 seems lost the major protein functional domain in Hgene partner, which is a essential gene due to the frame-shifted ORF.
NACC2-NTRK2 seems lost the major protein functional domain in Hgene partner, which is a transcription factor due to the frame-shifted ORF.
NACC2-NTRK2 seems lost the major protein functional domain in Tgene partner, which is a IUPHAR drug target due to the frame-shifted ORF.
NACC2-NTRK2 seems lost the major protein functional domain in Tgene partner, which is a kinase due to the frame-shifted ORF.
* DoF score (Degree of Frequency) = # partners X # break points X # cancer types
** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)

check button Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez
PartnerGeneGO IDGO termPubMed ID
HgeneNACC2

GO:0008285

negative regulation of cell proliferation

22926524

HgeneNACC2

GO:0034629

cellular protein-containing complex localization

22926524

HgeneNACC2

GO:0045892

negative regulation of transcription, DNA-templated

22926524

HgeneNACC2

GO:0051260

protein homooligomerization

22926524

HgeneNACC2

GO:1900477

negative regulation of G1/S transition of mitotic cell cycle by negative regulation of transcription from RNA polymerase II promoter

22926524

HgeneNACC2

GO:1902231

positive regulation of intrinsic apoptotic signaling pathway in response to DNA damage

22926524


check buttonFusion gene breakpoints across NACC2 (5'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.

check buttonFusion gene breakpoints across NTRK2 (3'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.

check button Fusion gene information from two resources (ChiTars 5.0 and ChimerDB 4.0)
* All genome coordinats were lifted-over on hg19.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
SourceDiseaseSampleHgeneHchrHbpHstrandTgeneTchrTbpTstrand
ChimerKB3..NACC2chr9

138905709

-NTRK2chr9

87359887

+


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Fusion Gene ORF analysis for NACC2-NTRK2

check button Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
ORFHenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrand
Frame-shiftENST00000371753ENST00000277120NACC2chr9

138905709

-NTRK2chr9

87359887

+
Frame-shiftENST00000371753ENST00000304053NACC2chr9

138905709

-NTRK2chr9

87359887

+
Frame-shiftENST00000371753ENST00000323115NACC2chr9

138905709

-NTRK2chr9

87359887

+
Frame-shiftENST00000371753ENST00000359847NACC2chr9

138905709

-NTRK2chr9

87359887

+
Frame-shiftENST00000371753ENST00000376208NACC2chr9

138905709

-NTRK2chr9

87359887

+
Frame-shiftENST00000371753ENST00000376213NACC2chr9

138905709

-NTRK2chr9

87359887

+
Frame-shiftENST00000371753ENST00000376214NACC2chr9

138905709

-NTRK2chr9

87359887

+
Frame-shiftENST00000371753ENST00000395866NACC2chr9

138905709

-NTRK2chr9

87359887

+
Frame-shiftENST00000371753ENST00000395882NACC2chr9

138905709

-NTRK2chr9

87359887

+
In-frameENST00000277554ENST00000277120NACC2chr9

138905709

-NTRK2chr9

87359887

+
In-frameENST00000277554ENST00000304053NACC2chr9

138905709

-NTRK2chr9

87359887

+
In-frameENST00000277554ENST00000323115NACC2chr9

138905709

-NTRK2chr9

87359887

+
In-frameENST00000277554ENST00000359847NACC2chr9

138905709

-NTRK2chr9

87359887

+
In-frameENST00000277554ENST00000376208NACC2chr9

138905709

-NTRK2chr9

87359887

+
In-frameENST00000277554ENST00000376213NACC2chr9

138905709

-NTRK2chr9

87359887

+
In-frameENST00000277554ENST00000376214NACC2chr9

138905709

-NTRK2chr9

87359887

+
In-frameENST00000277554ENST00000395866NACC2chr9

138905709

-NTRK2chr9

87359887

+
In-frameENST00000277554ENST00000395882NACC2chr9

138905709

-NTRK2chr9

87359887

+
intron-3CDSENST00000467669ENST00000277120NACC2chr9

138905709

-NTRK2chr9

87359887

+
intron-3CDSENST00000467669ENST00000304053NACC2chr9

138905709

-NTRK2chr9

87359887

+
intron-3CDSENST00000467669ENST00000323115NACC2chr9

138905709

-NTRK2chr9

87359887

+
intron-3CDSENST00000467669ENST00000359847NACC2chr9

138905709

-NTRK2chr9

87359887

+
intron-3CDSENST00000467669ENST00000376208NACC2chr9

138905709

-NTRK2chr9

87359887

+
intron-3CDSENST00000467669ENST00000376213NACC2chr9

138905709

-NTRK2chr9

87359887

+
intron-3CDSENST00000467669ENST00000376214NACC2chr9

138905709

-NTRK2chr9

87359887

+
intron-3CDSENST00000467669ENST00000395866NACC2chr9

138905709

-NTRK2chr9

87359887

+
intron-3CDSENST00000467669ENST00000395882NACC2chr9

138905709

-NTRK2chr9

87359887

+

check buttonORFfinder result based on the fusion transcript sequence of in-frame fusion genes.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandSeq length
(transcript)		BP loci
(transcript)		Predicted start
(transcript)		Predicted stop
(transcript)		Seq length
(amino acids)
ENST00000277554NACC2chr9138905709-ENST00000376214NTRK2chr987359887+4788131313062634442
ENST00000277554NACC2chr9138905709-ENST00000376213NTRK2chr987359887+4740131313062586426
ENST00000277554NACC2chr9138905709-ENST00000395882NTRK2chr987359887+667913131231334403
ENST00000277554NACC2chr9138905709-ENST00000304053NTRK2chr987359887+786113131231334403
ENST00000277554NACC2chr9138905709-ENST00000376208NTRK2chr987359887+781313131231334403
ENST00000277554NACC2chr9138905709-ENST00000277120NTRK2chr987359887+3692131313062634442
ENST00000277554NACC2chr9138905709-ENST00000323115NTRK2chr987359887+3473131313062586426
ENST00000277554NACC2chr9138905709-ENST00000359847NTRK2chr987359887+667513131231334403
ENST00000277554NACC2chr9138905709-ENST00000395866NTRK2chr987359887+203613131231334403

check buttonDeepORF prediction of the coding potential based on the fusion transcript sequence of in-frame fusion genes. DeepORF is a coding potential classifier based on convolutional neural network by comparing the real Ribo-seq data. If the no-coding score < 0.5 and coding score > 0.5, then the in-frame fusion transcript is predicted as being likely translated.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandNo-coding scoreCoding score

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Fusion Genomic Features for NACC2-NTRK2


check buttonFusionAI prediction of the potential fusion gene breakpoint based on the pre-mature RNA sequence context (+/- 5kb of individual partner genes, total 20kb length sequence). FusionAI is a fusion gene breakpoint classifier based on convolutional neural network by comparing the fusion positive and negative sequence context of ~ 20K fusion gene data. From here, we can have the relative potentency of the 20K genomic sequence how individual sequnce will be likely used as the gene fusion breakpoints.
HgeneHchrHbpHstrandTgeneTchrTbpTstrand1-pp (fusion gene breakpoint)

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions. We integrated a total of 44 different types of human genomic feature loci information across five big categories including virus integration sites, repeats, structural variants, chromatin states, and gene expression regulation. More details are in help page.

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions that are ovelapped with the top 1% feature importance score regions. More details are in help page.

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Fusion Protein Features for NACC2-NTRK2


check button Four levels of functional features of fusion genes
Go to FGviewer search page for the most frequent breakpoint (https://ccsmweb.uth.edu/FGviewer/chr9:/chr9:)
- FGviewer provides the online visualization of the retention search of the protein functional features across DNA, RNA, protein, and pathological levels.
- How to search
1. Put your fusion gene symbol.
2. Press the tab key until there will be shown the breakpoint information filled.
4. Go down and press 'Search' tab twice.
4. Go down to have the hyperlink of the search result.
5. Click the hyperlink.
6. See the FGviewer result for your fusion gene.
FGviewer

check buttonMain function of each fusion partner protein. (from UniProt)
HgeneTgene
NACC2

Q96BF6

NTRK2

Q16620

FUNCTION: Functions as a transcriptional repressor through its association with the NuRD complex. Recruits the NuRD complex to the promoter of MDM2, leading to the repression of MDM2 transcription and subsequent stability of p53/TP53. {ECO:0000269|PubMed:22926524}.FUNCTION: Receptor tyrosine kinase involved in the development and the maturation of the central and the peripheral nervous systems through regulation of neuron survival, proliferation, migration, differentiation, and synapse formation and plasticity (By similarity). Receptor for BDNF/brain-derived neurotrophic factor and NTF4/neurotrophin-4. Alternatively can also bind NTF3/neurotrophin-3 which is less efficient in activating the receptor but regulates neuron survival through NTRK2 (PubMed:7574684, PubMed:15494731). Upon ligand-binding, undergoes homodimerization, autophosphorylation and activation (PubMed:15494731). Recruits, phosphorylates and/or activates several downstream effectors including SHC1, FRS2, SH2B1, SH2B2 and PLCG1 that regulate distinct overlapping signaling cascades. Through SHC1, FRS2, SH2B1, SH2B2 activates the GRB2-Ras-MAPK cascade that regulates for instance neuronal differentiation including neurite outgrowth. Through the same effectors controls the Ras-PI3 kinase-AKT1 signaling cascade that mainly regulates growth and survival. Through PLCG1 and the downstream protein kinase C-regulated pathways controls synaptic plasticity. Thereby, plays a role in learning and memory by regulating both short term synaptic function and long-term potentiation. PLCG1 also leads to NF-Kappa-B activation and the transcription of genes involved in cell survival. Hence, it is able to suppress anoikis, the apoptosis resulting from loss of cell-matrix interactions. May also play a role in neutrophin-dependent calcium signaling in glial cells and mediate communication between neurons and glia. {ECO:0000250|UniProtKB:P15209, ECO:0000269|PubMed:15494731, ECO:0000269|PubMed:7574684}.

check buttonRetention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at

download page


* Minus value of BPloci means that the break pointn is located before the CDS.
- In-frame and retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note

- In-frame and not-retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note


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Fusion Gene Sequence for NACC2-NTRK2


check button For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. To have fusion amino acid sequence, we ran ORFfinder and chose the longest ORF among the all predicted ones.
>57095_57095_1_NACC2-NTRK2_NACC2_chr9_138905709_ENST00000277554_NTRK2_chr9_87359887_ENST00000277120_length(transcript)=3692nt_BP=1313nt
AAAGTCCATGGGAGCCGGAGCGCCGGGACGCCAAGCACTTCCTGCCGCGGGCGGCGCGCCGCAGCTGCCCAGGCCGGACCGGGCCGGGCG
CCCGCAGATGAGCCCCGCTAGGGCCGCCCCGCGCTGAGAGCCCAGCCCCGCCGCTGCCCGCCCGCCATGTCTCAGATGCTGCACATCGAG
ATCCCCAACTTCGGGAACACAGTGCTGGGCTGCCTGAACGAGCAGCGCCTGCTGGGCCTCTACTGCGATGTGTCCATCGTGGTCAAGGGC
CAGGCCTTCAAGGCCCACCGGGCGGTGCTGGCCGCCAGCAGCCTCTACTTCCGCGACCTGTTCAGCGGCAACAGCAAGAGCGCCTTCGAG
CTGCCCGGCTCCGTGCCGCCCGCCTGCTTCCAGCAGATCCTGTCCTTCTGCTACACGGGCAGGCTCACCATGACGGCCAGCGAGCAGCTC
GTGGTCATGTACACGGCCGGCTTCCTGCAGATCCAGCACATCGTGGAGCGCGGCACCGACCTCATGTTCAAGGTGAGCTCGCCCCACTGC
GACTCGCAGACCGCTGTGATCGAGGACGCCGGCTCCGAGCCCCAGAGCCCCTGCAACCAGCTGCAGCCGGCCGCCGCCGCCGCGGCCCCC
TACGTCGTGTCCCCCTCGGTGCCCATCCCGCTGCTGACCCGAGTAAAGCATGAAGCCATGGAGCTGCCGCCGGCCGGCCCAGGCCTGGCC
CCCAAGCGCCCGCTGGAGACGGGGCCCCGGGACGGCGTGGCGGTGGCCGCGGGGGCTGCGGTGGCGGCGGGCACAGCCCCTCTCAAACTG
CCCCGTGTCTCCTACTACGGGGTGCCCAGCCTGGCCACCCTCATCCCCGGCATCCAGCAGATGCCCTACCCCCAGGGGGAGCGGACCAGT
CCAGGCGCCAGCAGCCTGCCCACCACCGACAGCCCCACCTCGTACCACAACGAGGAGGACGAGGAGGACGACGAGGCCTACGACACCATG
GTGGAGGAGCAGTACGGCCAGATGTACATCAAGGCCTCCGGCAGCTATGCAGTGCAAGAGAAGCCTGAGCCAGTGCCGCTGGAGAGCCGC
TCCTGCGTCCTCATCCGCCGCGACCTCGTGGCCCTACCTGCCAGCCTCATCAGCCAGATCGGATACCGCTGCCATCCCAAGCTCTACTCG
GAAGGGGACCCCGGGGAGAAGCTGGAGCTGGTGGCAGGCTCTGGGGTCTACATCACACGCGGCCAGCTGATGAACTGCCACCTGTGTGCA
GGGGTGAAGCATAAGGTCTTGCTGCGGAGGCTCCTGGCCACCTTCTTTGACAGATTATGGAACTGCAGCGAATGACATCGGGGACACCAC
GAACAGAAGTAATGAAATCCCTTCCACAGACGTCACTGATAAAACCGGTCGGGAACATCTCTCGGTCTATGCTGTGGTGGTGATTGCGTC
TGTGGTGGGATTTTGCCTTTTGGTAATGCTGTTTCTGCTTAAGTTGGCAAGACACTCCAAGTTTGGCATGAAAGATTTCTCATGGTTTGG
ATTTGGGAAAGTAAAATCAAGACAAGGTGTTGGCCCAGCCTCCGTTATCAGCAATGATGATGACTCTGCCAGCCCACTCCATCACATCTC
CAATGGGAGTAACACTCCATCTTCTTCGGAAGGTGGCCCAGATGCTGTCATTATTGGAATGACCAAGATCCCTGTCATTGAAAATCCCCA
GTACTTTGGCATCACCAACAGTCAGCTCAAGCCAGACACATTTGTTCAGCACATCAAGCGACATAACATTGTTCTGAAAAGGGAGCTAGG
CGAAGGAGCCTTTGGAAAAGTGTTCCTAGCTGAATGCTATAACCTCTGTCCTGAGCAGGACAAGATCTTGGTGGCAGTGAAGACCCTGAA
GGATGCCAGTGACAATGCACGCAAGGACTTCCACCGTGAGGCCGAGCTCCTGACCAACCTCCAGCATGAGCACATCGTCAAGTTCTATGG
CGTCTGCGTGGAGGGCGACCCCCTCATCATGGTCTTTGAGTACATGAAGCATGGGGACCTCAACAAGTTCCTCAGGGCACACGGCCCTGA
TGCCGTGCTGATGGCTGAGGGCAACCCGCCCACGGAACTGACGCAGTCGCAGATGCTGCATATAGCCCAGCAGATCGCCGCGGGCATGGT
CTACCTGGCGTCCCAGCACTTCGTGCACCGCGATTTGGCCACCAGGAACTGCCTGGTCGGGGAGAACTTGCTGGTGAAAATCGGGGACTT
TGGGATGTCCCGGGACGTGTACAGCACTGACTACTACAGGGTCGGTGGCCACACAATGCTGCCCATTCGCTGGATGCCTCCAGAGAGCAT
CATGTACAGGAAATTCACGACGGAAAGCGACGTCTGGAGCCTGGGGGTCGTGTTGTGGGAGATTTTCACCTATGGCAAACAGCCCTGGTA
CCAGCTGTCAAACAATGAGGTGATAGAGTGTATCACTCAGGGCCGAGTCCTGCAGCGACCCCGCACGTGCCCCCAGGAGGTGTATGAGCT
GATGCTGGGGTGCTGGCAGCGAGAGCCCCACATGAGGAAGAACATCAAGGGCATCCATACCCTCCTTCAGAACTTGGCCAAGGCATCTCC
GGTCTACCTGGACATTCTAGGCTAGGGCCCTTTTCCCCAGACCGATCCTTCCCAACGTACTCCTCAGACGGGCTGAGAGGATGAACATCT
TTTAACTGCCGCTGGAGGCCACCAAGCTGCTCTCCTTCACTCTGACAGTATTAACATCAAAGACTCCGAGAAGCTCTCGAGGGAAGCAGT
GTGTACTTCTTCATCCATAGACACAGTATTGACTTCTTTTTGGCATTATCTCTTTCTCTCTTTCCATCTCCCTTGGTTGTTCCTTTTTCT
TTTTTTAAATTTTCTTTTTCTTTTTTTTTTCGTCTTCCCTGCTTCACGATTCTTACCCTTTCTTTTGAATCAATCTGGCTTCTGCATTAC
TATTAACTCTGCATAGACAAAGGCCTTAACAAACGTAATTTGTTATATCAGCAGACACTCCAGTTTGCCCACCACAACTAACAATGCCTT
GTTGTATTCCTGCCTTTGATGTGGATGAAAAAAAGGGAAAACAAATATTTCACTTAAACTTTGTCACTTCTGCTGTACAGATATCGAGAG
TTTCTATGGATTCACTTCTATTTATTTATTATTATTACTGTTCTTATTGTTTTTGGATGGCTTAAGCCTGTGTATAAAAAAGAAAACTTG
TGTTCAATCTGTGAAGCCTTTATCTATGGGAGATTAAAACCAGAGAGAAAGAAGATTTATTATGAACCGCAATATGGGAGGAACAAAGAC
AACCACTGGGATCAGCTGGTGTCAGTCCCTACTTAGGAAATACTCAGCAACTGTTAGCTGGGAAGAATGTATTCGGCACCTTCCCCTGAG
GACCTTTCTGAGGAGTAAAAAGACTACTGGCCTCTGTGCCATGGATGATTCTTTTCCCATCACCAGAAATGATAGCGTGCAGTAGAGAGC
AAAGATGGCTTCCGTGAGACACAAGATGGCGCATAGTGTGCTCGGACACAGTTTTGTCTTCGTAGGTTGTGATGATAGCACTGGTTTGTT
TCTCAAGCGCTATCCACAGAACCTTTGTCAACTTCAGTTGAAAAGAGGTGGATTCATGTCCAGAGCTCATTTCGGGGTCAGGTGGGAAAG

>57095_57095_1_NACC2-NTRK2_NACC2_chr9_138905709_ENST00000277554_NTRK2_chr9_87359887_ENST00000277120_length(amino acids)=442AA_BP=2
MTDYGTAANDIGDTTNRSNEIPSTDVTDKTGREHLSVYAVVVIASVVGFCLLVMLFLLKLARHSKFGMKDFSWFGFGKVKSRQGVGPASV
ISNDDDSASPLHHISNGSNTPSSSEGGPDAVIIGMTKIPVIENPQYFGITNSQLKPDTFVQHIKRHNIVLKRELGEGAFGKVFLAECYNL
CPEQDKILVAVKTLKDASDNARKDFHREAELLTNLQHEHIVKFYGVCVEGDPLIMVFEYMKHGDLNKFLRAHGPDAVLMAEGNPPTELTQ
SQMLHIAQQIAAGMVYLASQHFVHRDLATRNCLVGENLLVKIGDFGMSRDVYSTDYYRVGGHTMLPIRWMPPESIMYRKFTTESDVWSLG

--------------------------------------------------------------
>57095_57095_2_NACC2-NTRK2_NACC2_chr9_138905709_ENST00000277554_NTRK2_chr9_87359887_ENST00000304053_length(transcript)=7861nt_BP=1313nt
AAAGTCCATGGGAGCCGGAGCGCCGGGACGCCAAGCACTTCCTGCCGCGGGCGGCGCGCCGCAGCTGCCCAGGCCGGACCGGGCCGGGCG
CCCGCAGATGAGCCCCGCTAGGGCCGCCCCGCGCTGAGAGCCCAGCCCCGCCGCTGCCCGCCCGCCATGTCTCAGATGCTGCACATCGAG
ATCCCCAACTTCGGGAACACAGTGCTGGGCTGCCTGAACGAGCAGCGCCTGCTGGGCCTCTACTGCGATGTGTCCATCGTGGTCAAGGGC
CAGGCCTTCAAGGCCCACCGGGCGGTGCTGGCCGCCAGCAGCCTCTACTTCCGCGACCTGTTCAGCGGCAACAGCAAGAGCGCCTTCGAG
CTGCCCGGCTCCGTGCCGCCCGCCTGCTTCCAGCAGATCCTGTCCTTCTGCTACACGGGCAGGCTCACCATGACGGCCAGCGAGCAGCTC
GTGGTCATGTACACGGCCGGCTTCCTGCAGATCCAGCACATCGTGGAGCGCGGCACCGACCTCATGTTCAAGGTGAGCTCGCCCCACTGC
GACTCGCAGACCGCTGTGATCGAGGACGCCGGCTCCGAGCCCCAGAGCCCCTGCAACCAGCTGCAGCCGGCCGCCGCCGCCGCGGCCCCC
TACGTCGTGTCCCCCTCGGTGCCCATCCCGCTGCTGACCCGAGTAAAGCATGAAGCCATGGAGCTGCCGCCGGCCGGCCCAGGCCTGGCC
CCCAAGCGCCCGCTGGAGACGGGGCCCCGGGACGGCGTGGCGGTGGCCGCGGGGGCTGCGGTGGCGGCGGGCACAGCCCCTCTCAAACTG
CCCCGTGTCTCCTACTACGGGGTGCCCAGCCTGGCCACCCTCATCCCCGGCATCCAGCAGATGCCCTACCCCCAGGGGGAGCGGACCAGT
CCAGGCGCCAGCAGCCTGCCCACCACCGACAGCCCCACCTCGTACCACAACGAGGAGGACGAGGAGGACGACGAGGCCTACGACACCATG
GTGGAGGAGCAGTACGGCCAGATGTACATCAAGGCCTCCGGCAGCTATGCAGTGCAAGAGAAGCCTGAGCCAGTGCCGCTGGAGAGCCGC
TCCTGCGTCCTCATCCGCCGCGACCTCGTGGCCCTACCTGCCAGCCTCATCAGCCAGATCGGATACCGCTGCCATCCCAAGCTCTACTCG
GAAGGGGACCCCGGGGAGAAGCTGGAGCTGGTGGCAGGCTCTGGGGTCTACATCACACGCGGCCAGCTGATGAACTGCCACCTGTGTGCA
GGGGTGAAGCATAAGGTCTTGCTGCGGAGGCTCCTGGCCACCTTCTTTGACAGATTATGGAACTGCAGCGAATGACATCGGGGACACCAC
GAACAGAAGTAATGAAATCCCTTCCACAGACGTCACTGATAAAACCGGTCGGGAACATCTCTCGGTCTATGCTGTGGTGGTGATTGCGTC
TGTGGTGGGATTTTGCCTTTTGGTAATGCTGTTTCTGCTTAAGTTGGCAAGACACTCCAAGTTTGGCATGAAAGATTTCTCATGGTTTGG
ATTTGGGAAAGTAAAATCAAGACAAGGTGTTGGCCCAGCCTCCGTTATCAGCAATGATGATGACTCTGCCAGCCCACTCCATCACATCTC
CAATGGGAGTAACACTCCATCTTCTTCGGAAGGTGGCCCAGATGCTGTCATTATTGGAATGACCAAGATCCCTGTCATTGAAAATCCCCA
GTACTTTGGCATCACCAACAGTCAGCTCAAGCCAGACACATGGCCCAGAGGTTCCCCCAAGACCGCCTGATAATAATTTGGTATTTGGAG
GCTCCTGTGTCACTGCAGGAACTAAAGGAGGCTAAATCCATGCCTGATGGAGGAGAAGAGTTCTATGGTTATCTGCAAATTCTGGCCAGA
CAACATCTTGACGTCACTCCTTAGCTTCCATAACCTAGCCAAGCAAGAAGTTGCCTTTCCAAGACAAAGCAGTGTGCTCTAATGACTAAC
CCCTCAAAGTACTATGCCACTTTAACTATAGACCCATCTCCTCGATCAATCAGGATGGCAAGATGGAGCTGAGGAGCTCAGCAACATCAA
GTCTGGAGTTGGTCTTTAACTCAACTAGCTCGTTTAGACGTGTCTGAACACCACATCACCTGACAGCACGGGGTGGTTTCCCAGTAAAAT
TTACAAACTCAGCTCAAGGGCAGCTGTGTTGCTTTCCTTTCCTTGACTGCTGAGAAACTTTTTGACAGGGAACAATGGAAACACACCTTC
TGAGCTGAAACAAACAAACAGAAACAAAACATACTAACCAGCAAAATCCCCAAATCATCAATCTTGGGTTCTCTTGAAGGGCAGGAGTGT
GTTTTATCTTCTCCCGTCGGAGCAAACACTATAGATGTCCTCCCTAAAATTCTGTCTTCCCTAGAGCAGCCTTGTAAATTAGCTAGGGTC
CTAGGGTTGAGGCCTAAATCAACTTAAAATTGTCTCTAAATATGTACCTGGATGTGTTTGTACTTGCAGAGCATGCCCTCTTCATGTGCC
TAGGGCTAGTAACTCCCTGTGGCAGAGGCATGTAAAGTATTCTGACTTTTTTTTTTTCAACTTAATTCCATTTCCAATGAAATGGATTTT
TAAAAATTTTCTCCAGAGTGTGCCATACTTCTCCAGCTATTATAGTTAATGTGTGTGTATCCTTGTGTATATGTGTGTTTGTGTGTGCAT
ATGTGTTTTCCTAGTGGTTACATGCTTACTAGGCAATTATGTAAATAAGCACAGATTCATAGGCCAGCTAGGCCTGAGGAAAGAAGACAT
TATAAAGGGAGGGAGTATTTTAACATTAGCTAAAGCTATCACACAAGGCACCCATTCTGCTCCCCTCAACAGCCACAGCCCACTTCGTCC
TTGTCTTACCAATAAGGGGAAAGGCTGGAGGTGATATTTTTCACAGAACCGCAGAGGTTTTGAACATATTTGCAACATTACTTTGAGTAC
ACATGAGCAAAAATTCTGAATTACATCCAGGACCCCAGAAGCTCATTAGATCAAAGAGTGCGGGGCCCCTCAGAGTTACCAGAGATTATC
TGCAGACTTCAGTGCAATCGAATGACCATGGTCCATTTTGATGGTCAGAGGTAGGACTGAAAAACGGGTAGAAACAATTGCTTTAGCGCT
TCCTTCTGTACTTTGCCTATTAATGTTTTGTCTTTCAAAAATATATTTTCTCCTAATTGTTTAATTGGCCAAATAATGGCTGCTTTGGGA
GTTGTTTGTATGCCTTGGAAGGCCATGGCCTGCACTTTAAAAATAAGCTAAGTCCATTCTGCCCAGCACGAGCATTAGGACAGAGAATGC
ACTTATTTTAGGATCCTTAAAAATTGCTTCTTTTATGGCACACTGGGTTGACGACTCATCTCGTGGGAGCCTTCATGGCACATTGCTGCT
GTTCTGCAGGTCCCAATACAATTCCTTCCCCCTCTCAGTGCCACGGCCCCCCCATTGCTAGCTACAACAATTTGATATCATATTCCCTTT
TCAACTCCAAAGGAGATGATAAGAAGCTATCAAATAATGCTTTAAAAAAGCAACTTGAGTTTCTTAAAAGAAAGGAAATGAATACATGCT
GCATAATTACATTTAAAATGTAAGCCATGTTATTATAAGCCGCACTGAGATGAAGATTTGTTAGCAAACCAGTTTCAAGCACACTCACAG
TGAAGTAAAATCATGTTTTTAGCATCTGACCATTGGGTAATATTATTCTTTGTTATCAAAAGAGAAATATCACCCAAGTATAGTATACTT
AGACCTCCTAGAGGAAACACTCCAGTCCTAAGCTTGGTGTCTGAAAAGAAAAACAAAAATAAAGATTATGGATTTAGGTCAGGGAGACAG
AGTGATATTCTGAAGACTGTGTTTACTCCCTCATCATCGGCCAACCAAGATGGAGTTCTGCATCCTGCACATATCAGACATTTCAGTCCA
ATTTCACCAAAGCATCAGTGATGTTCTAGAAGCATCCCAGCAGATGGAGGATCCTAATGTATTTGTTCTGGGTATTTCCCAAGGCCCAGC
CTGACTGGAGTGTGTGTACCAACAGGATGAATCCAATCAAGCTACGCCCCCATTTTGGTTTCGGATTGGCCACTCTTGCATGTGCTAGTA
GATTGTGGACCAGGACCAGCTGAGCAAACACAGTTGCAGAGTAGCCTCCTATGTTGCTAAGAAGCTCCTGCTACCCAGGTGCTTTGAACA
ATTGAGTGCTCCCTCTGGTTAAGTAGAGATGGCACCACCGGAGTTTTTCTTGGATGTGAGGCTCAATCCTTTACGGCAGCTATTATAACA
AAGTGAAGGTTTTCTCCCTGGGAAATGCAGCTTTTCTCTGTCTTTACTAATTCTGCCAGCCTGTGAGAGTAACCACCGTAGCTGGGCTTC
TTCTCAGATTAATTGTCATGCCAGGTCTCCTTCCTGGGGAGCTGTGATGCTGCTCTGAGGTTGATTGCTGAGGTTGTAGTGGGTTTTTGT
TTGTTTTTGTTTAGTTTTTCTTGATTGTTCTTCTTTCTCTTGAATGGCAAGAGAAGAAACACTTTCTCTAACCCACGGCCAGGAAGGAAA
TGGGGAGAGAGCTACTTCTTAGTTCAACCTGGTTGCCACATAAAGGAATCTCTCTCCTTGGACTCAGCCCCTAACTGGAAGCAAGAGCCA
CTGCCCTCTGAGACTGAGAGAGCAGCCCGAGGAGGAGATGAATCCATTCTGCCCTTTGTTTGGGTTTGCTTCCTGTCAGTGAGAGAATGC
TGAGGCAGTTCCTGTTATGTGAAACTTTCATTTTTAAAACCAGGACAGTCCTAAACAGACTGGAATGAGTTGGTCAATCCCAGTTGGTAT
AGGCCCAATGATTTTTGCTAGTAAGATAGGATTGTCTTCCTCACCCAAAATGCCTTCAAGTGCCCTAAAATGGGTATTTTAAAATAAGAA
TAAATAATGTAGATTTAGTAGAAAACCTGGAAAACATAAGAAACAAAGATGAAACGAAAAGTCCCATGTAATTCCACCAGTTAGAGTTAA
CCACTGATATCGTTTGGATATATGGCTTTCTAGTCTTGTGGATATCCTTTTAATCTCTTGTAATATAAAGTCTGACCATATGTGTCCTTG
CATTTGTTTGTACTGGACTCTGTTAATATTTCTATAGTAATGGCTCACTTTGGGGAGATTGTGCTGCACAGTGTGTAGGAAGCACATTGG
GTGTATTATTCCCAGTTTTGTATTTTGTATTTCCTTGGAGATGTGCAGGGGTTAAGAGCGGGGGTCTGGCCATAGCTGGCCACGTCAGAC
TCTCATATGGTAAGTATCACAGAGCACATGAGGCCTGTGTTATGCGCTGGAAAGACTCAGGAAATGAGAGGCTCTCTTGTTCTGACAAGG
CAGGCTGAGAGCTCTCATTTAGGGTCATCACTCCAGATAACTCCAAATGCAGTTTATTGCTCAACTGAAGCAGATGATCACTTTTTGCCT
CCAAGTTCTTCACCCTAGCTAGCTCCTTTCAAAGAGCCGAGTATGCTGGATCTTAAAGGGCCAAACTAGTTACATCTCATACATTTCCTG
ATGTTTAGGGATGCCTTCACTTCCATCAAGGATACCTTGGCTGTGCAAGGACCTCTGATAGCTGGAGTCTCCTTTTGGTCACTCCCAGCT
TTGCTTAAACTTGATGGAGTTTGCTGTCCAGTGATCCCCGGATCTTTCATCATGAAAGCCTTCCTTCCTCTCCTGATGTCTCAGGCCTCT
AGACCTAGACTGGGGTTCTGGCAAGGAGGCCTCTATCAATAGTATGACATCCAATAATATGTTAGTGTTGATATTTTGCACAGTAATATT
AAGTTTAAGAGATTATAAAAATGAGTTCAAATGAATAAGTTCCTGTGATGTAAGAGATTAGATATGTGTGATTTCAGAACCAAAGGCAGG
GGGGAATCCCAGAAAGAAAACAATAATATAATCCTAGTTTCTATATATTATTTTTATTCATTACTGTATATGGGTAGAGATCAATATTCT
TTCTTATGCTGTTACTATTAATTAACACATTTTTTAACCATGCCATTGAACTTTTGGGTGCATTAAAGTGGAACCCAAGCTCCTCATTAG
ATAATAATGGCATTTGGACTGAGTGCCATATTCCTAAATTTCCAATAAAGTGGTTGATATAGAGAGGACAGGATAAAGCCCTATAGTGTG
CAGTTATATCAAAACAGCTAGTCTCCACTTTAGGGAATGCCTTTACTAGAGATTACATGAAATGTCTGCTTATAAAATAAGCAGAGATGG
CACCACTAAGCAGCCACCTGAATTGTTTTCCTACAGGAATGATTACTTTTCAGATCCATTTATGTTTTCATGCTCAATACTTACTCCCCT
TCCCTGCAACACCCAAAGAGTTTACTTTTGCAAGTCATTTGGTCTTCAGTCTACTACTGAGGAATAGAGAGGCACTAACTGCTTTACCCA
GGATCAGAACTCATGTTCTTACCTTCTATTAATAGAGTACTTGAGCCAGATGGACTAACTGGTCTCACATTTTCTCTATCTTGGTTTTAC
TTCCATAAACATCAATATCTTTACCCACATGATTTTTCCATCCTCCCATTTTTTTCCATATGTATTAGGGTTCAGGAACTATGATGCTAA
TGATCACATTTCTTCCTAGTTCCTAATTTCATTAGTGCCATTTCCTGATATCTACAGAAACAATTATCAATACATGTAGCTGCTTGAGCC
TTATTTAGAAGGCTAGCCTTTCTTTTCCAAGTGCTGTCAGAATGTATACATTTAGTCTGTCTTTTTCCCTTTTAGGAGTCTTTGTTCTGG
GTTGATGGCAAAATTCCTCTTTTTACATGTGAGATTTTTGATTTCACTGAATTCTACCTAGATTTTTATGGACATTGGATTTTAAAGAGG
AAAACACTCATTTTCTTAGTAAGATATTGGTGATACATAGCTATGCCATTGATTTCCATACTCCTGAGCTTTGGGGAGGGAGACAGTGGC
CAAGTAGCAGGCAGAATAAGATCATCACTCATGTCCTGAATCAATCACACTTTCCTTCTCGGATTGTGTATATGCTCTGCCACTTCCTAC
ATATTACATCCTGAGTTTTTAAGTAAAGTGGATCTTAGCCAGATTTGAGTCTAATGGCTGATTCATCGGCATAGTTCTTGGCGTTAACAT
CTCAGTGTCCTCTTTAGTTCTCTTTGAGGATTCATGTCATTGAGGGCCTTTGTGCCTCCACTTGTCTCAGTATGAGGAAGAACTTTGGTG
TGAGGGCGGAGCTATGTGAAGGGTTGCTGGGTTGGGGGATTAGTTCATATGGTCCCCATGCCATCTATTTACTTTTGGAGAGAGGGGACT
TTGAGTGGGTGGGTATGGATAGATGTTCCTCAAGGAAACCCTGCTGGCTAATGGGCACTACATCTGTGTATTACTGTGATTCTCTCTGTA
AGCTCCCCATGTGGCCAAGGACCCCCCTCCTACCAGGGCACTTCCTGCCACCTCATTGCACTGGTCTCAACCATTCAGCCTGCTGCTGCT
GCACCATGTTGGGCTGCGGTAGGATAGGGAAGGGGTTCTGTTGATTGCTAAATGTTGCCTAACTTTATTTCCCTCTCCCACATTTCATGC
AAGGGAGCGGACCTAACACATGACTTGCATTCTCTTCCTATGTTCAGAAACTCCAGGGCTTGCCCACGTGTATGTATGAGTGACCAATGG
AGCTTGGAATTCTTTATCTATATGATCTGTCCGAAAATGAGATCTTTTGTACTGGAATTTGTGATGTAGTTGATCATTCAGAGCCAAACG

>57095_57095_2_NACC2-NTRK2_NACC2_chr9_138905709_ENST00000277554_NTRK2_chr9_87359887_ENST00000304053_length(amino acids)=403AA_BP=
MRAQPRRCPPAMSQMLHIEIPNFGNTVLGCLNEQRLLGLYCDVSIVVKGQAFKAHRAVLAASSLYFRDLFSGNSKSAFELPGSVPPACFQ
QILSFCYTGRLTMTASEQLVVMYTAGFLQIQHIVERGTDLMFKVSSPHCDSQTAVIEDAGSEPQSPCNQLQPAAAAAAPYVVSPSVPIPL
LTRVKHEAMELPPAGPGLAPKRPLETGPRDGVAVAAGAAVAAGTAPLKLPRVSYYGVPSLATLIPGIQQMPYPQGERTSPGASSLPTTDS
PTSYHNEEDEEDDEAYDTMVEEQYGQMYIKASGSYAVQEKPEPVPLESRSCVLIRRDLVALPASLISQIGYRCHPKLYSEGDPGEKLELV

--------------------------------------------------------------
>57095_57095_3_NACC2-NTRK2_NACC2_chr9_138905709_ENST00000277554_NTRK2_chr9_87359887_ENST00000323115_length(transcript)=3473nt_BP=1313nt
AAAGTCCATGGGAGCCGGAGCGCCGGGACGCCAAGCACTTCCTGCCGCGGGCGGCGCGCCGCAGCTGCCCAGGCCGGACCGGGCCGGGCG
CCCGCAGATGAGCCCCGCTAGGGCCGCCCCGCGCTGAGAGCCCAGCCCCGCCGCTGCCCGCCCGCCATGTCTCAGATGCTGCACATCGAG
ATCCCCAACTTCGGGAACACAGTGCTGGGCTGCCTGAACGAGCAGCGCCTGCTGGGCCTCTACTGCGATGTGTCCATCGTGGTCAAGGGC
CAGGCCTTCAAGGCCCACCGGGCGGTGCTGGCCGCCAGCAGCCTCTACTTCCGCGACCTGTTCAGCGGCAACAGCAAGAGCGCCTTCGAG
CTGCCCGGCTCCGTGCCGCCCGCCTGCTTCCAGCAGATCCTGTCCTTCTGCTACACGGGCAGGCTCACCATGACGGCCAGCGAGCAGCTC
GTGGTCATGTACACGGCCGGCTTCCTGCAGATCCAGCACATCGTGGAGCGCGGCACCGACCTCATGTTCAAGGTGAGCTCGCCCCACTGC
GACTCGCAGACCGCTGTGATCGAGGACGCCGGCTCCGAGCCCCAGAGCCCCTGCAACCAGCTGCAGCCGGCCGCCGCCGCCGCGGCCCCC
TACGTCGTGTCCCCCTCGGTGCCCATCCCGCTGCTGACCCGAGTAAAGCATGAAGCCATGGAGCTGCCGCCGGCCGGCCCAGGCCTGGCC
CCCAAGCGCCCGCTGGAGACGGGGCCCCGGGACGGCGTGGCGGTGGCCGCGGGGGCTGCGGTGGCGGCGGGCACAGCCCCTCTCAAACTG
CCCCGTGTCTCCTACTACGGGGTGCCCAGCCTGGCCACCCTCATCCCCGGCATCCAGCAGATGCCCTACCCCCAGGGGGAGCGGACCAGT
CCAGGCGCCAGCAGCCTGCCCACCACCGACAGCCCCACCTCGTACCACAACGAGGAGGACGAGGAGGACGACGAGGCCTACGACACCATG
GTGGAGGAGCAGTACGGCCAGATGTACATCAAGGCCTCCGGCAGCTATGCAGTGCAAGAGAAGCCTGAGCCAGTGCCGCTGGAGAGCCGC
TCCTGCGTCCTCATCCGCCGCGACCTCGTGGCCCTACCTGCCAGCCTCATCAGCCAGATCGGATACCGCTGCCATCCCAAGCTCTACTCG
GAAGGGGACCCCGGGGAGAAGCTGGAGCTGGTGGCAGGCTCTGGGGTCTACATCACACGCGGCCAGCTGATGAACTGCCACCTGTGTGCA
GGGGTGAAGCATAAGGTCTTGCTGCGGAGGCTCCTGGCCACCTTCTTTGACAGATTATGGAACTGCAGCGAATGACATCGGGGACACCAC
GAACAGAAGTAATGAAATCCCTTCCACAGACGTCACTGATAAAACCGGTCGGGAACATCTCTCGGTCTATGCTGTGGTGGTGATTGCGTC
TGTGGTGGGATTTTGCCTTTTGGTAATGCTGTTTCTGCTTAAGTTGGCAAGACACTCCAAGTTTGGCATGAAAGGCCCAGCCTCCGTTAT
CAGCAATGATGATGACTCTGCCAGCCCACTCCATCACATCTCCAATGGGAGTAACACTCCATCTTCTTCGGAAGGTGGCCCAGATGCTGT
CATTATTGGAATGACCAAGATCCCTGTCATTGAAAATCCCCAGTACTTTGGCATCACCAACAGTCAGCTCAAGCCAGACACATTTGTTCA
GCACATCAAGCGACATAACATTGTTCTGAAAAGGGAGCTAGGCGAAGGAGCCTTTGGAAAAGTGTTCCTAGCTGAATGCTATAACCTCTG
TCCTGAGCAGGACAAGATCTTGGTGGCAGTGAAGACCCTGAAGGATGCCAGTGACAATGCACGCAAGGACTTCCACCGTGAGGCCGAGCT
CCTGACCAACCTCCAGCATGAGCACATCGTCAAGTTCTATGGCGTCTGCGTGGAGGGCGACCCCCTCATCATGGTCTTTGAGTACATGAA
GCATGGGGACCTCAACAAGTTCCTCAGGGCACACGGCCCTGATGCCGTGCTGATGGCTGAGGGCAACCCGCCCACGGAACTGACGCAGTC
GCAGATGCTGCATATAGCCCAGCAGATCGCCGCGGGCATGGTCTACCTGGCGTCCCAGCACTTCGTGCACCGCGATTTGGCCACCAGGAA
CTGCCTGGTCGGGGAGAACTTGCTGGTGAAAATCGGGGACTTTGGGATGTCCCGGGACGTGTACAGCACTGACTACTACAGGGTCGGTGG
CCACACAATGCTGCCCATTCGCTGGATGCCTCCAGAGAGCATCATGTACAGGAAATTCACGACGGAAAGCGACGTCTGGAGCCTGGGGGT
CGTGTTGTGGGAGATTTTCACCTATGGCAAACAGCCCTGGTACCAGCTGTCAAACAATGAGGTGATAGAGTGTATCACTCAGGGCCGAGT
CCTGCAGCGACCCCGCACGTGCCCCCAGGAGGTGTATGAGCTGATGCTGGGGTGCTGGCAGCGAGAGCCCCACATGAGGAAGAACATCAA
GGGCATCCATACCCTCCTTCAGAACTTGGCCAAGGCATCTCCGGTCTACCTGGACATTCTAGGCTAGGGCCCTTTTCCCCAGACCGATCC
TTCCCAACGTACTCCTCAGACGGGCTGAGAGGATGAACATCTTTTAACTGCCGCTGGAGGCCACCAAGCTGCTCTCCTTCACTCTGACAG
TATTAACATCAAAGACTCCGAGAAGCTCTCGAGGGAAGCAGTGTGTACTTCTTCATCCATAGACACAGTATTGACTTCTTTTTGGCATTA
TCTCTTTCTCTCTTTCCATCTCCCTTGGTTGTTCCTTTTTCTTTTTTTAAATTTTCTTTTTCTTTTTTTTTTCGTCTTCCCTGCTTCACG
ATTCTTACCCTTTCTTTTGAATCAATCTGGCTTCTGCATTACTATTAACTCTGCATAGACAAAGGCCTTAACAAACGTAATTTGTTATAT
CAGCAGACACTCCAGTTTGCCCACCACAACTAACAATGCCTTGTTGTATTCCTGCCTTTGATGTGGATGAAAAAAAGGGAAAACAAATAT
TTCACTTAAACTTTGTCACTTCTGCTGTACAGATATCGAGAGTTTCTATGGATTCACTTCTATTTATTTATTATTATTACTGTTCTTATT
GTTTTTGGATGGCTTAAGCCTGTGTATAAAAAAGAAAACTTGTGTTCAATCTGTGAAGCCTTTATCTATGGGAGATTAAAACCAGAGAGA
AAGAAGATTTATTATGAACCGCAATATGGGAGGAACAAAGACAACCACTGGGATCAGCTGGTGTCAGTCCCTACTTAGGAAATACTCAGC
AACTGTTAGCTGGGAAGAATGTATTCGGCACCTTCCCCTGAGGACCTTTCTGAGGAGTAAAAAGACTACTGGCCTCTGTGCCATGGATGA

>57095_57095_3_NACC2-NTRK2_NACC2_chr9_138905709_ENST00000277554_NTRK2_chr9_87359887_ENST00000323115_length(amino acids)=426AA_BP=2
MTDYGTAANDIGDTTNRSNEIPSTDVTDKTGREHLSVYAVVVIASVVGFCLLVMLFLLKLARHSKFGMKGPASVISNDDDSASPLHHISN
GSNTPSSSEGGPDAVIIGMTKIPVIENPQYFGITNSQLKPDTFVQHIKRHNIVLKRELGEGAFGKVFLAECYNLCPEQDKILVAVKTLKD
ASDNARKDFHREAELLTNLQHEHIVKFYGVCVEGDPLIMVFEYMKHGDLNKFLRAHGPDAVLMAEGNPPTELTQSQMLHIAQQIAAGMVY
LASQHFVHRDLATRNCLVGENLLVKIGDFGMSRDVYSTDYYRVGGHTMLPIRWMPPESIMYRKFTTESDVWSLGVVLWEIFTYGKQPWYQ

--------------------------------------------------------------
>57095_57095_4_NACC2-NTRK2_NACC2_chr9_138905709_ENST00000277554_NTRK2_chr9_87359887_ENST00000359847_length(transcript)=6675nt_BP=1313nt
AAAGTCCATGGGAGCCGGAGCGCCGGGACGCCAAGCACTTCCTGCCGCGGGCGGCGCGCCGCAGCTGCCCAGGCCGGACCGGGCCGGGCG
CCCGCAGATGAGCCCCGCTAGGGCCGCCCCGCGCTGAGAGCCCAGCCCCGCCGCTGCCCGCCCGCCATGTCTCAGATGCTGCACATCGAG
ATCCCCAACTTCGGGAACACAGTGCTGGGCTGCCTGAACGAGCAGCGCCTGCTGGGCCTCTACTGCGATGTGTCCATCGTGGTCAAGGGC
CAGGCCTTCAAGGCCCACCGGGCGGTGCTGGCCGCCAGCAGCCTCTACTTCCGCGACCTGTTCAGCGGCAACAGCAAGAGCGCCTTCGAG
CTGCCCGGCTCCGTGCCGCCCGCCTGCTTCCAGCAGATCCTGTCCTTCTGCTACACGGGCAGGCTCACCATGACGGCCAGCGAGCAGCTC
GTGGTCATGTACACGGCCGGCTTCCTGCAGATCCAGCACATCGTGGAGCGCGGCACCGACCTCATGTTCAAGGTGAGCTCGCCCCACTGC
GACTCGCAGACCGCTGTGATCGAGGACGCCGGCTCCGAGCCCCAGAGCCCCTGCAACCAGCTGCAGCCGGCCGCCGCCGCCGCGGCCCCC
TACGTCGTGTCCCCCTCGGTGCCCATCCCGCTGCTGACCCGAGTAAAGCATGAAGCCATGGAGCTGCCGCCGGCCGGCCCAGGCCTGGCC
CCCAAGCGCCCGCTGGAGACGGGGCCCCGGGACGGCGTGGCGGTGGCCGCGGGGGCTGCGGTGGCGGCGGGCACAGCCCCTCTCAAACTG
CCCCGTGTCTCCTACTACGGGGTGCCCAGCCTGGCCACCCTCATCCCCGGCATCCAGCAGATGCCCTACCCCCAGGGGGAGCGGACCAGT
CCAGGCGCCAGCAGCCTGCCCACCACCGACAGCCCCACCTCGTACCACAACGAGGAGGACGAGGAGGACGACGAGGCCTACGACACCATG
GTGGAGGAGCAGTACGGCCAGATGTACATCAAGGCCTCCGGCAGCTATGCAGTGCAAGAGAAGCCTGAGCCAGTGCCGCTGGAGAGCCGC
TCCTGCGTCCTCATCCGCCGCGACCTCGTGGCCCTACCTGCCAGCCTCATCAGCCAGATCGGATACCGCTGCCATCCCAAGCTCTACTCG
GAAGGGGACCCCGGGGAGAAGCTGGAGCTGGTGGCAGGCTCTGGGGTCTACATCACACGCGGCCAGCTGATGAACTGCCACCTGTGTGCA
GGGGTGAAGCATAAGGTCTTGCTGCGGAGGCTCCTGGCCACCTTCTTTGACAGATTATGGAACTGCAGCGAATGACATCGGGGACACCAC
GAACAGAAGTAATGAAATCCCTTCCACAGACGTCACTGATAAAACCGGTCGGGAACATCTCTCGGTCTATGCTGTGGTGGTGATTGCGTC
TGTGGTGGGATTTTGCCTTTTGGTAATGCTGTTTCTGCTTAAGTTGGCAAGACACTCCAAGTTTGGCATGAAAGGTTTTGTTTTGTTTCA
TAAGATCCCACTGGATGGGTAGCTGAAATAAAGGAAAAGACAGAGAAAGGGGCTGTGGTGCTTGTTGGTTGATGCTGCCATGTAAGCTGG
ACTCCTGGGACTGCTGTTGGCTTATCCCGGGAAGTGCTGCTTATCTGGGGTTTTCTGGTAGATGTGGGCGGTGTTTGGAGGCTGTACTAT
ATGAAGCCTGCATATACTGTGAGCTGTGATTGGGGAACACCAATGCAGAGGTAACTCTCAGGCAGCTAAGCAGCACCTCAAGAAAACATG
TTAAATTAATGCTTCTCTTCTTACAGTAGTTCAAATACAAAACTGAAATGAAATCCCATTGGATTGTACTTCTCTTCTGAAAAGTGTGCT
TTTTGACCCTACTGGACATTTATTGACTTAATTGCTTCTGTTTATTAAAATTGACCTGCAAAGTTAAAAAAAAATTAAAGTTGAGAACAG
GTATAAGTGCACACTGAATAGTCTAATCTACATGTAACACATATTTTAGTGTGATTTTCTATACTCTAATCAGCACTGAATTCAGAGGGT
TTGACTTTTTCATCTATAACACAGTGACTAAAAGAGTTAAGGGTATATATACCATCACTTTGGGACTTGGTAGTATTATTAAAAGGTTAT
TTCCTTCACTGTCAATAAAAGTCCAAATGTTTAGCTTAGGTCTGAGAGTCAAACAATGTTAAGGATTGTCTTAAAGTTCCTTAGCCAGCA
AAACAAAACAAAACAAAACAAACAAATGAAAAACGTTTAAAAAGAAGAAGAAGAAAAAAAACAAGAACAAGCAGCAACAGCTGTTTTGTT
GGGGCTATAGATTTAAGTTAGGCATAGTCAATTTCAGAATAACTAAGAGTGGAATATATGCATATGGTGAAATTATAACCTTGCCCTTTT
TTATTTGCCCTCTGCGATCCACCTGCTTTTTAGAAGTCTGCCGAGTGAGAAGGCCACAGTATCTCATGCTGTTTGCATTACAGAACTGCA
GCTTTTCTACTCTGAAAAGGCCTGGGAGCAGAATGGCTGGCCTGCTGTGAGCAGGAGAGGAGATTCTAAGAAGGATAGTCCCCCCTACAA
CATACTGTCATACTGCTGGGTTTTCATGGGTAGGAAAGCTTGTCCTGACCCCAGCAGCAAAGAGGTGGCAGGTCGCTAATGAATATATGC
TTTATAATGTCCTTCTTCATTGCTGAGAGGGCAGCCTTAGAGCTGTGGATTTCTGCATCCCCCCTGAGTCTGACCCATGGACACCTGTTT
CATTCACTTTAGCATCACAGTGACCTTTGTATGCTCTGTTCAGTCTGTGTCAGGCAGTATGCTTGTCCTGAAGAGAGGTTTGGCTATCCC
CACCCCACCCCACCCCACCCTGTTCCTTTTTTATCAGGAGGACTTCAGAGCCAGGCCTGCAGCATTTTGTTTGAAAACACAATCAGCTCT
GACAGTTAGACATGCACACAGACGCCATAGCTGGATTGGAAACATTGATGTTTTAAAAATTTATTTTTTTTGGAAATAGTTGCACAAATG
CTGCAATTTAGCTTTAAGGTTCTATAGATTTTTAACTAGTCCAACACAGTCAGAAACATTGTTTTGAATCCTCTGTAAACCAAGGCATTA
ATCTTAATAAACCAGGATCCATTTAGGTACCACTTGATATAAAAAGGATATCCATAATGAATATTTTATACTGCATCCTTTACATTAGCC
ACTAAATACGTTATTGCTTGATGAAGACCTTTCACAGAATCCTATGGATTGCAGCATTTCACTTGGCTACTTCATACCCATGCCTTAAAG
AGGGGCAGTTTCTCAAAAGCAGAAACATGCCGCCAGTTCTCAAGTTTTCCTCCTAACTCCATTTGAATGTAAGGGCAGCTGGCCCCCAAT
GTGGGGAGGTCCGAACATTTTCTGAATTCCCATTTTCTTGTTCGCGGCTAAATGACAGTTTCTGTCATTACTTAGATTCCGATCTTTCCC
AAAGGTGTTGATTTACAAAGAGGCCAGCTAATAGCAGAAATCATGACCCTGAAAGAGAGATGAAATTCAAGCTGTGAGCCAGGCAGGAGC
TCAGTATGGCAAAGGTTCTTGAGAATCAGCCATTTGGTACAAAAAAGATTTTTAAAGCTTTTATGTTATACCATGGAGCCATAGAAAGGC
TATGGATTGTTTAAGAACTATTTTAAAGTGTTCCAGACCCAAAAAGGAAAAATAAAAAAAAAGGAATATTTGTACCCAACAGCTAGAAGG
ATTGCAAGGTAGATTTTTGTTTTAAAATGGAGAGAAGTGGACAGATAAGGCCATTTAATATATCAAAGATCAGTTGACATCTCCTAGGGA
ATGATGAAAACAGCAGGCTATTAGAAAATTATTTCATATAGTTCTCGTGTTCTTTTCTTTTTTTTAATCCCTGAAGGGATGATCAGTAAC
ATAGCTTCTCTTTTCTGTACTCTAGACCACCCCTTTTCATCATTTTGCTTTTTATGTCTCCCATAAGAAATGTGCTTTTTAGAGCTTCCT
AATGCATGTGTTGCATTATTGCAGCATTAGAAAAGGAGAGGTAGCATTTTTGCTGAAATCGGGCCTGTCACTCTCCAATAAAGGTTCTGG
CACTTCAATGCCAGGCAGGTCTCCTAAATGAACAGAATGATCTGTGTGAGCCGATGCCTGCCCTTCCAGAGGGGCCACTGTCCCCAGCCG
CAGCCAACTGTGTCCCACAGGAATGGGAGCCTAGGTTTCCAAATCTTGTGATTCTTTAGGAGAAACATGAAACCTGGATTTCGTGTGAAA
TGTCCCGATTGTTAAAAAGTTGGCTCAATTATTTTTAAAACATTTTGTAAGCCAACAAAAGTCTGTGGGCTGCCAGTTTATTACTTTTGT
CTTAAAACATGATCATTGTTCTCTCACGGTATCCTTCTGTCTTCCCGTTGCAAATTCACTTTTCTTTCTTCCTGACATTGCCATTGAGGG
CTTTGTTACCACAAGCTAAGAAACTGAGTTTAACAGCCCAGTTATCTGCAACATGTCAATTACCTTTGCTCCTCTCCTGTGATTCCCACC
ATGCTGTGACCCTCAGCTGTCTCCCTTTGCTGGGAATTCTGCACCAATGTCTCCCCTCAACCCATTCCCTGGTTGGTCCTACTCCCGTGT
GGCCAGAGACATCCTAGCAAATCCTTCCTCCTATTATATCTGACACTAATTTCTTTTCAACAGCGCTCATGTCTCTTGGCCCAGTCAGGT
GCTGCCAGGTTTAGATAGGAAAGTACATGTCCCATTTTCATGGGTGCCCTTAATGTGGTCCACGTCCTATATCTTATTATATTTACTCAT
GGCTCAATGGGGGCCTCCAGAGACCCTCTCAGGCTGCTGAGCTAGACTAAGGAATGCATCCACCGTCATCACATGAGACACTGACTCTGT
GACGACAAAAGTACAAACAGTCTGAGGCTAAGAAAGGTTCATCTCACAACAGGAAAAACAAATCTCAACACACATTAGAGATAATTGATT
CAGGGGTTTTCTCTCCCAGTCTCCCAGCAGGGACTGATTTCATTTCTGACCCACTAGGTTTTCTTTCCAGAAATAGGTAGCAAGGACAAG
AACTAAACAATCCCAGCCCCACCCAGCAACACAGAACACAGGAGTTTGCTTTTGGCTTCTCACTCTCCAAGTAACCCTGAATTAGGCCCA
GAATGGCTGAGGCTTGGAGCATCTCCTCAGACAGAGCAGAGGCGACACCTCTTCAGGGGTGTGTGGAGTAAATAGCTCGAAGAGCTGAAG
ACAGAAAACCAGTTTCACGCCAGGTGCGAGAGAGAGCATAATGGAGGGAAGCCCGCTTTCTCTCTCCTCTTCTTTTCTCTTTATTTCTTT
AGAGCACTTGACTTTTTTTTCTCTCTCTCTCTAGTATTCTAAACTGACCCCATGACCAACTGAGAATTTATTTTTGTTTCATTGGTTGTT
TCACAGAATTAGAACACACACGACTTTTTATTCCTCCATTGCAAAATGGAATCAAGATACTACACAAGACCTGTGCTTTCTTCCTTTGCA
TGATTTACACCTCCGCCTGTTTTGGTGCTAGCTGTCTAGAACTTCTCTCTTGGTTTGAATCTGATTCCTTCACACTACACTAGAAGTTTA
TTTCATCTTGTTTTGTCTAGACTCCAGATACAGAGGGACAGCTGGACTGAGGACAAGCAATTCCATCTAGCATAGGGTCTCTCAGGGTTG
GTGCATCCAGCCACATGGGCAGGGCCAGTCACATCTAGTCTATGTCCCCAGAGCCCTTGGAGTTGCGCAGCTTAGCTGACTTGACTCCAA
GGAAATTAGTACAGAAGTAACCACTCTATTAAGTGTGTTCTGCTATGTTCACATGCCTGTAGTACCTGCAAACCATGCCAGGTTCATCTA
AAGACATAGGGGAAGATTAAGGACTCTTTTGGACAGACCATGAATTGAATTTGCTGCCAGGTGCTGCCAGACTGAATTTGGCTGACAGAA
CTCCCAGCCCAGGAAAGTTCCATGACAATGACTGTCGCAGAAGGAAATTTCCCACTAAAGTCAGTCCATTTTCAAGTTTTGGTCTTCAGA
GACAAAAGAACGTCCCAGCCACCTGATTTTGATGGTGAGGTAACTCTAAGTTGAATTCAGGCTAGTGTTGCAGTATAGCTTTGGCATGTT
CATGAGTGAGCACCCAGAATGTGTTGAACCAACCCCCACCCCTAACTACTGACTATGACTGCAGTGGGTTTTTATGGGGAAAAAAAGTGT
GAAAAGCAAAAAGAAAGGAACAGAGATTTTTTATCACCTTTATTGTAAGACAGTCCATTTATGAATTGAGTATAAACACATACAAAGTAA
CAAGAGATTCCTAAGAAACGCAAATCCTTGAGTTTCACGCACTTCATGTTCAACCATTTGCTGTAATCCAGAGGCAGCCTGTGAATCATT
CTCATGCCCTGTTTTTTTTTTTTTTTTCCTATAATGTTCTGGGTTTAAAAGCCATCTTTTCCACATTTTCTGTAAATAATGGATAATCAT
TTTAAAAATTTTTATTTTTAGTGCTGTTTTAACAATGTAGATAGATCATAAATGTACTTGCTGAATTCAATCATTTTTAACAAGCCAATA

>57095_57095_4_NACC2-NTRK2_NACC2_chr9_138905709_ENST00000277554_NTRK2_chr9_87359887_ENST00000359847_length(amino acids)=403AA_BP=
MRAQPRRCPPAMSQMLHIEIPNFGNTVLGCLNEQRLLGLYCDVSIVVKGQAFKAHRAVLAASSLYFRDLFSGNSKSAFELPGSVPPACFQ
QILSFCYTGRLTMTASEQLVVMYTAGFLQIQHIVERGTDLMFKVSSPHCDSQTAVIEDAGSEPQSPCNQLQPAAAAAAPYVVSPSVPIPL
LTRVKHEAMELPPAGPGLAPKRPLETGPRDGVAVAAGAAVAAGTAPLKLPRVSYYGVPSLATLIPGIQQMPYPQGERTSPGASSLPTTDS
PTSYHNEEDEEDDEAYDTMVEEQYGQMYIKASGSYAVQEKPEPVPLESRSCVLIRRDLVALPASLISQIGYRCHPKLYSEGDPGEKLELV

--------------------------------------------------------------
>57095_57095_5_NACC2-NTRK2_NACC2_chr9_138905709_ENST00000277554_NTRK2_chr9_87359887_ENST00000376208_length(transcript)=7813nt_BP=1313nt
AAAGTCCATGGGAGCCGGAGCGCCGGGACGCCAAGCACTTCCTGCCGCGGGCGGCGCGCCGCAGCTGCCCAGGCCGGACCGGGCCGGGCG
CCCGCAGATGAGCCCCGCTAGGGCCGCCCCGCGCTGAGAGCCCAGCCCCGCCGCTGCCCGCCCGCCATGTCTCAGATGCTGCACATCGAG
ATCCCCAACTTCGGGAACACAGTGCTGGGCTGCCTGAACGAGCAGCGCCTGCTGGGCCTCTACTGCGATGTGTCCATCGTGGTCAAGGGC
CAGGCCTTCAAGGCCCACCGGGCGGTGCTGGCCGCCAGCAGCCTCTACTTCCGCGACCTGTTCAGCGGCAACAGCAAGAGCGCCTTCGAG
CTGCCCGGCTCCGTGCCGCCCGCCTGCTTCCAGCAGATCCTGTCCTTCTGCTACACGGGCAGGCTCACCATGACGGCCAGCGAGCAGCTC
GTGGTCATGTACACGGCCGGCTTCCTGCAGATCCAGCACATCGTGGAGCGCGGCACCGACCTCATGTTCAAGGTGAGCTCGCCCCACTGC
GACTCGCAGACCGCTGTGATCGAGGACGCCGGCTCCGAGCCCCAGAGCCCCTGCAACCAGCTGCAGCCGGCCGCCGCCGCCGCGGCCCCC
TACGTCGTGTCCCCCTCGGTGCCCATCCCGCTGCTGACCCGAGTAAAGCATGAAGCCATGGAGCTGCCGCCGGCCGGCCCAGGCCTGGCC
CCCAAGCGCCCGCTGGAGACGGGGCCCCGGGACGGCGTGGCGGTGGCCGCGGGGGCTGCGGTGGCGGCGGGCACAGCCCCTCTCAAACTG
CCCCGTGTCTCCTACTACGGGGTGCCCAGCCTGGCCACCCTCATCCCCGGCATCCAGCAGATGCCCTACCCCCAGGGGGAGCGGACCAGT
CCAGGCGCCAGCAGCCTGCCCACCACCGACAGCCCCACCTCGTACCACAACGAGGAGGACGAGGAGGACGACGAGGCCTACGACACCATG
GTGGAGGAGCAGTACGGCCAGATGTACATCAAGGCCTCCGGCAGCTATGCAGTGCAAGAGAAGCCTGAGCCAGTGCCGCTGGAGAGCCGC
TCCTGCGTCCTCATCCGCCGCGACCTCGTGGCCCTACCTGCCAGCCTCATCAGCCAGATCGGATACCGCTGCCATCCCAAGCTCTACTCG
GAAGGGGACCCCGGGGAGAAGCTGGAGCTGGTGGCAGGCTCTGGGGTCTACATCACACGCGGCCAGCTGATGAACTGCCACCTGTGTGCA
GGGGTGAAGCATAAGGTCTTGCTGCGGAGGCTCCTGGCCACCTTCTTTGACAGATTATGGAACTGCAGCGAATGACATCGGGGACACCAC
GAACAGAAGTAATGAAATCCCTTCCACAGACGTCACTGATAAAACCGGTCGGGAACATCTCTCGGTCTATGCTGTGGTGGTGATTGCGTC
TGTGGTGGGATTTTGCCTTTTGGTAATGCTGTTTCTGCTTAAGTTGGCAAGACACTCCAAGTTTGGCATGAAAGGCCCAGCCTCCGTTAT
CAGCAATGATGATGACTCTGCCAGCCCACTCCATCACATCTCCAATGGGAGTAACACTCCATCTTCTTCGGAAGGTGGCCCAGATGCTGT
CATTATTGGAATGACCAAGATCCCTGTCATTGAAAATCCCCAGTACTTTGGCATCACCAACAGTCAGCTCAAGCCAGACACATGGCCCAG
AGGTTCCCCCAAGACCGCCTGATAATAATTTGGTATTTGGAGGCTCCTGTGTCACTGCAGGAACTAAAGGAGGCTAAATCCATGCCTGAT
GGAGGAGAAGAGTTCTATGGTTATCTGCAAATTCTGGCCAGACAACATCTTGACGTCACTCCTTAGCTTCCATAACCTAGCCAAGCAAGA
AGTTGCCTTTCCAAGACAAAGCAGTGTGCTCTAATGACTAACCCCTCAAAGTACTATGCCACTTTAACTATAGACCCATCTCCTCGATCA
ATCAGGATGGCAAGATGGAGCTGAGGAGCTCAGCAACATCAAGTCTGGAGTTGGTCTTTAACTCAACTAGCTCGTTTAGACGTGTCTGAA
CACCACATCACCTGACAGCACGGGGTGGTTTCCCAGTAAAATTTACAAACTCAGCTCAAGGGCAGCTGTGTTGCTTTCCTTTCCTTGACT
GCTGAGAAACTTTTTGACAGGGAACAATGGAAACACACCTTCTGAGCTGAAACAAACAAACAGAAACAAAACATACTAACCAGCAAAATC
CCCAAATCATCAATCTTGGGTTCTCTTGAAGGGCAGGAGTGTGTTTTATCTTCTCCCGTCGGAGCAAACACTATAGATGTCCTCCCTAAA
ATTCTGTCTTCCCTAGAGCAGCCTTGTAAATTAGCTAGGGTCCTAGGGTTGAGGCCTAAATCAACTTAAAATTGTCTCTAAATATGTACC
TGGATGTGTTTGTACTTGCAGAGCATGCCCTCTTCATGTGCCTAGGGCTAGTAACTCCCTGTGGCAGAGGCATGTAAAGTATTCTGACTT
TTTTTTTTTCAACTTAATTCCATTTCCAATGAAATGGATTTTTAAAAATTTTCTCCAGAGTGTGCCATACTTCTCCAGCTATTATAGTTA
ATGTGTGTGTATCCTTGTGTATATGTGTGTTTGTGTGTGCATATGTGTTTTCCTAGTGGTTACATGCTTACTAGGCAATTATGTAAATAA
GCACAGATTCATAGGCCAGCTAGGCCTGAGGAAAGAAGACATTATAAAGGGAGGGAGTATTTTAACATTAGCTAAAGCTATCACACAAGG
CACCCATTCTGCTCCCCTCAACAGCCACAGCCCACTTCGTCCTTGTCTTACCAATAAGGGGAAAGGCTGGAGGTGATATTTTTCACAGAA
CCGCAGAGGTTTTGAACATATTTGCAACATTACTTTGAGTACACATGAGCAAAAATTCTGAATTACATCCAGGACCCCAGAAGCTCATTA
GATCAAAGAGTGCGGGGCCCCTCAGAGTTACCAGAGATTATCTGCAGACTTCAGTGCAATCGAATGACCATGGTCCATTTTGATGGTCAG
AGGTAGGACTGAAAAACGGGTAGAAACAATTGCTTTAGCGCTTCCTTCTGTACTTTGCCTATTAATGTTTTGTCTTTCAAAAATATATTT
TCTCCTAATTGTTTAATTGGCCAAATAATGGCTGCTTTGGGAGTTGTTTGTATGCCTTGGAAGGCCATGGCCTGCACTTTAAAAATAAGC
TAAGTCCATTCTGCCCAGCACGAGCATTAGGACAGAGAATGCACTTATTTTAGGATCCTTAAAAATTGCTTCTTTTATGGCACACTGGGT
TGACGACTCATCTCGTGGGAGCCTTCATGGCACATTGCTGCTGTTCTGCAGGTCCCAATACAATTCCTTCCCCCTCTCAGTGCCACGGCC
CCCCCATTGCTAGCTACAACAATTTGATATCATATTCCCTTTTCAACTCCAAAGGAGATGATAAGAAGCTATCAAATAATGCTTTAAAAA
AGCAACTTGAGTTTCTTAAAAGAAAGGAAATGAATACATGCTGCATAATTACATTTAAAATGTAAGCCATGTTATTATAAGCCGCACTGA
GATGAAGATTTGTTAGCAAACCAGTTTCAAGCACACTCACAGTGAAGTAAAATCATGTTTTTAGCATCTGACCATTGGGTAATATTATTC
TTTGTTATCAAAAGAGAAATATCACCCAAGTATAGTATACTTAGACCTCCTAGAGGAAACACTCCAGTCCTAAGCTTGGTGTCTGAAAAG
AAAAACAAAAATAAAGATTATGGATTTAGGTCAGGGAGACAGAGTGATATTCTGAAGACTGTGTTTACTCCCTCATCATCGGCCAACCAA
GATGGAGTTCTGCATCCTGCACATATCAGACATTTCAGTCCAATTTCACCAAAGCATCAGTGATGTTCTAGAAGCATCCCAGCAGATGGA
GGATCCTAATGTATTTGTTCTGGGTATTTCCCAAGGCCCAGCCTGACTGGAGTGTGTGTACCAACAGGATGAATCCAATCAAGCTACGCC
CCCATTTTGGTTTCGGATTGGCCACTCTTGCATGTGCTAGTAGATTGTGGACCAGGACCAGCTGAGCAAACACAGTTGCAGAGTAGCCTC
CTATGTTGCTAAGAAGCTCCTGCTACCCAGGTGCTTTGAACAATTGAGTGCTCCCTCTGGTTAAGTAGAGATGGCACCACCGGAGTTTTT
CTTGGATGTGAGGCTCAATCCTTTACGGCAGCTATTATAACAAAGTGAAGGTTTTCTCCCTGGGAAATGCAGCTTTTCTCTGTCTTTACT
AATTCTGCCAGCCTGTGAGAGTAACCACCGTAGCTGGGCTTCTTCTCAGATTAATTGTCATGCCAGGTCTCCTTCCTGGGGAGCTGTGAT
GCTGCTCTGAGGTTGATTGCTGAGGTTGTAGTGGGTTTTTGTTTGTTTTTGTTTAGTTTTTCTTGATTGTTCTTCTTTCTCTTGAATGGC
AAGAGAAGAAACACTTTCTCTAACCCACGGCCAGGAAGGAAATGGGGAGAGAGCTACTTCTTAGTTCAACCTGGTTGCCACATAAAGGAA
TCTCTCTCCTTGGACTCAGCCCCTAACTGGAAGCAAGAGCCACTGCCCTCTGAGACTGAGAGAGCAGCCCGAGGAGGAGATGAATCCATT
CTGCCCTTTGTTTGGGTTTGCTTCCTGTCAGTGAGAGAATGCTGAGGCAGTTCCTGTTATGTGAAACTTTCATTTTTAAAACCAGGACAG
TCCTAAACAGACTGGAATGAGTTGGTCAATCCCAGTTGGTATAGGCCCAATGATTTTTGCTAGTAAGATAGGATTGTCTTCCTCACCCAA
AATGCCTTCAAGTGCCCTAAAATGGGTATTTTAAAATAAGAATAAATAATGTAGATTTAGTAGAAAACCTGGAAAACATAAGAAACAAAG
ATGAAACGAAAAGTCCCATGTAATTCCACCAGTTAGAGTTAACCACTGATATCGTTTGGATATATGGCTTTCTAGTCTTGTGGATATCCT
TTTAATCTCTTGTAATATAAAGTCTGACCATATGTGTCCTTGCATTTGTTTGTACTGGACTCTGTTAATATTTCTATAGTAATGGCTCAC
TTTGGGGAGATTGTGCTGCACAGTGTGTAGGAAGCACATTGGGTGTATTATTCCCAGTTTTGTATTTTGTATTTCCTTGGAGATGTGCAG
GGGTTAAGAGCGGGGGTCTGGCCATAGCTGGCCACGTCAGACTCTCATATGGTAAGTATCACAGAGCACATGAGGCCTGTGTTATGCGCT
GGAAAGACTCAGGAAATGAGAGGCTCTCTTGTTCTGACAAGGCAGGCTGAGAGCTCTCATTTAGGGTCATCACTCCAGATAACTCCAAAT
GCAGTTTATTGCTCAACTGAAGCAGATGATCACTTTTTGCCTCCAAGTTCTTCACCCTAGCTAGCTCCTTTCAAAGAGCCGAGTATGCTG
GATCTTAAAGGGCCAAACTAGTTACATCTCATACATTTCCTGATGTTTAGGGATGCCTTCACTTCCATCAAGGATACCTTGGCTGTGCAA
GGACCTCTGATAGCTGGAGTCTCCTTTTGGTCACTCCCAGCTTTGCTTAAACTTGATGGAGTTTGCTGTCCAGTGATCCCCGGATCTTTC
ATCATGAAAGCCTTCCTTCCTCTCCTGATGTCTCAGGCCTCTAGACCTAGACTGGGGTTCTGGCAAGGAGGCCTCTATCAATAGTATGAC
ATCCAATAATATGTTAGTGTTGATATTTTGCACAGTAATATTAAGTTTAAGAGATTATAAAAATGAGTTCAAATGAATAAGTTCCTGTGA
TGTAAGAGATTAGATATGTGTGATTTCAGAACCAAAGGCAGGGGGGAATCCCAGAAAGAAAACAATAATATAATCCTAGTTTCTATATAT
TATTTTTATTCATTACTGTATATGGGTAGAGATCAATATTCTTTCTTATGCTGTTACTATTAATTAACACATTTTTTAACCATGCCATTG
AACTTTTGGGTGCATTAAAGTGGAACCCAAGCTCCTCATTAGATAATAATGGCATTTGGACTGAGTGCCATATTCCTAAATTTCCAATAA
AGTGGTTGATATAGAGAGGACAGGATAAAGCCCTATAGTGTGCAGTTATATCAAAACAGCTAGTCTCCACTTTAGGGAATGCCTTTACTA
GAGATTACATGAAATGTCTGCTTATAAAATAAGCAGAGATGGCACCACTAAGCAGCCACCTGAATTGTTTTCCTACAGGAATGATTACTT
TTCAGATCCATTTATGTTTTCATGCTCAATACTTACTCCCCTTCCCTGCAACACCCAAAGAGTTTACTTTTGCAAGTCATTTGGTCTTCA
GTCTACTACTGAGGAATAGAGAGGCACTAACTGCTTTACCCAGGATCAGAACTCATGTTCTTACCTTCTATTAATAGAGTACTTGAGCCA
GATGGACTAACTGGTCTCACATTTTCTCTATCTTGGTTTTACTTCCATAAACATCAATATCTTTACCCACATGATTTTTCCATCCTCCCA
TTTTTTTCCATATGTATTAGGGTTCAGGAACTATGATGCTAATGATCACATTTCTTCCTAGTTCCTAATTTCATTAGTGCCATTTCCTGA
TATCTACAGAAACAATTATCAATACATGTAGCTGCTTGAGCCTTATTTAGAAGGCTAGCCTTTCTTTTCCAAGTGCTGTCAGAATGTATA
CATTTAGTCTGTCTTTTTCCCTTTTAGGAGTCTTTGTTCTGGGTTGATGGCAAAATTCCTCTTTTTACATGTGAGATTTTTGATTTCACT
GAATTCTACCTAGATTTTTATGGACATTGGATTTTAAAGAGGAAAACACTCATTTTCTTAGTAAGATATTGGTGATACATAGCTATGCCA
TTGATTTCCATACTCCTGAGCTTTGGGGAGGGAGACAGTGGCCAAGTAGCAGGCAGAATAAGATCATCACTCATGTCCTGAATCAATCAC
ACTTTCCTTCTCGGATTGTGTATATGCTCTGCCACTTCCTACATATTACATCCTGAGTTTTTAAGTAAAGTGGATCTTAGCCAGATTTGA
GTCTAATGGCTGATTCATCGGCATAGTTCTTGGCGTTAACATCTCAGTGTCCTCTTTAGTTCTCTTTGAGGATTCATGTCATTGAGGGCC
TTTGTGCCTCCACTTGTCTCAGTATGAGGAAGAACTTTGGTGTGAGGGCGGAGCTATGTGAAGGGTTGCTGGGTTGGGGGATTAGTTCAT
ATGGTCCCCATGCCATCTATTTACTTTTGGAGAGAGGGGACTTTGAGTGGGTGGGTATGGATAGATGTTCCTCAAGGAAACCCTGCTGGC
TAATGGGCACTACATCTGTGTATTACTGTGATTCTCTCTGTAAGCTCCCCATGTGGCCAAGGACCCCCCTCCTACCAGGGCACTTCCTGC
CACCTCATTGCACTGGTCTCAACCATTCAGCCTGCTGCTGCTGCACCATGTTGGGCTGCGGTAGGATAGGGAAGGGGTTCTGTTGATTGC
TAAATGTTGCCTAACTTTATTTCCCTCTCCCACATTTCATGCAAGGGAGCGGACCTAACACATGACTTGCATTCTCTTCCTATGTTCAGA
AACTCCAGGGCTTGCCCACGTGTATGTATGAGTGACCAATGGAGCTTGGAATTCTTTATCTATATGATCTGTCCGAAAATGAGATCTTTT

>57095_57095_5_NACC2-NTRK2_NACC2_chr9_138905709_ENST00000277554_NTRK2_chr9_87359887_ENST00000376208_length(amino acids)=403AA_BP=
MRAQPRRCPPAMSQMLHIEIPNFGNTVLGCLNEQRLLGLYCDVSIVVKGQAFKAHRAVLAASSLYFRDLFSGNSKSAFELPGSVPPACFQ
QILSFCYTGRLTMTASEQLVVMYTAGFLQIQHIVERGTDLMFKVSSPHCDSQTAVIEDAGSEPQSPCNQLQPAAAAAAPYVVSPSVPIPL
LTRVKHEAMELPPAGPGLAPKRPLETGPRDGVAVAAGAAVAAGTAPLKLPRVSYYGVPSLATLIPGIQQMPYPQGERTSPGASSLPTTDS
PTSYHNEEDEEDDEAYDTMVEEQYGQMYIKASGSYAVQEKPEPVPLESRSCVLIRRDLVALPASLISQIGYRCHPKLYSEGDPGEKLELV

--------------------------------------------------------------
>57095_57095_6_NACC2-NTRK2_NACC2_chr9_138905709_ENST00000277554_NTRK2_chr9_87359887_ENST00000376213_length(transcript)=4740nt_BP=1313nt
AAAGTCCATGGGAGCCGGAGCGCCGGGACGCCAAGCACTTCCTGCCGCGGGCGGCGCGCCGCAGCTGCCCAGGCCGGACCGGGCCGGGCG
CCCGCAGATGAGCCCCGCTAGGGCCGCCCCGCGCTGAGAGCCCAGCCCCGCCGCTGCCCGCCCGCCATGTCTCAGATGCTGCACATCGAG
ATCCCCAACTTCGGGAACACAGTGCTGGGCTGCCTGAACGAGCAGCGCCTGCTGGGCCTCTACTGCGATGTGTCCATCGTGGTCAAGGGC
CAGGCCTTCAAGGCCCACCGGGCGGTGCTGGCCGCCAGCAGCCTCTACTTCCGCGACCTGTTCAGCGGCAACAGCAAGAGCGCCTTCGAG
CTGCCCGGCTCCGTGCCGCCCGCCTGCTTCCAGCAGATCCTGTCCTTCTGCTACACGGGCAGGCTCACCATGACGGCCAGCGAGCAGCTC
GTGGTCATGTACACGGCCGGCTTCCTGCAGATCCAGCACATCGTGGAGCGCGGCACCGACCTCATGTTCAAGGTGAGCTCGCCCCACTGC
GACTCGCAGACCGCTGTGATCGAGGACGCCGGCTCCGAGCCCCAGAGCCCCTGCAACCAGCTGCAGCCGGCCGCCGCCGCCGCGGCCCCC
TACGTCGTGTCCCCCTCGGTGCCCATCCCGCTGCTGACCCGAGTAAAGCATGAAGCCATGGAGCTGCCGCCGGCCGGCCCAGGCCTGGCC
CCCAAGCGCCCGCTGGAGACGGGGCCCCGGGACGGCGTGGCGGTGGCCGCGGGGGCTGCGGTGGCGGCGGGCACAGCCCCTCTCAAACTG
CCCCGTGTCTCCTACTACGGGGTGCCCAGCCTGGCCACCCTCATCCCCGGCATCCAGCAGATGCCCTACCCCCAGGGGGAGCGGACCAGT
CCAGGCGCCAGCAGCCTGCCCACCACCGACAGCCCCACCTCGTACCACAACGAGGAGGACGAGGAGGACGACGAGGCCTACGACACCATG
GTGGAGGAGCAGTACGGCCAGATGTACATCAAGGCCTCCGGCAGCTATGCAGTGCAAGAGAAGCCTGAGCCAGTGCCGCTGGAGAGCCGC
TCCTGCGTCCTCATCCGCCGCGACCTCGTGGCCCTACCTGCCAGCCTCATCAGCCAGATCGGATACCGCTGCCATCCCAAGCTCTACTCG
GAAGGGGACCCCGGGGAGAAGCTGGAGCTGGTGGCAGGCTCTGGGGTCTACATCACACGCGGCCAGCTGATGAACTGCCACCTGTGTGCA
GGGGTGAAGCATAAGGTCTTGCTGCGGAGGCTCCTGGCCACCTTCTTTGACAGATTATGGAACTGCAGCGAATGACATCGGGGACACCAC
GAACAGAAGTAATGAAATCCCTTCCACAGACGTCACTGATAAAACCGGTCGGGAACATCTCTCGGTCTATGCTGTGGTGGTGATTGCGTC
TGTGGTGGGATTTTGCCTTTTGGTAATGCTGTTTCTGCTTAAGTTGGCAAGACACTCCAAGTTTGGCATGAAAGGCCCAGCCTCCGTTAT
CAGCAATGATGATGACTCTGCCAGCCCACTCCATCACATCTCCAATGGGAGTAACACTCCATCTTCTTCGGAAGGTGGCCCAGATGCTGT
CATTATTGGAATGACCAAGATCCCTGTCATTGAAAATCCCCAGTACTTTGGCATCACCAACAGTCAGCTCAAGCCAGACACATTTGTTCA
GCACATCAAGCGACATAACATTGTTCTGAAAAGGGAGCTAGGCGAAGGAGCCTTTGGAAAAGTGTTCCTAGCTGAATGCTATAACCTCTG
TCCTGAGCAGGACAAGATCTTGGTGGCAGTGAAGACCCTGAAGGATGCCAGTGACAATGCACGCAAGGACTTCCACCGTGAGGCCGAGCT
CCTGACCAACCTCCAGCATGAGCACATCGTCAAGTTCTATGGCGTCTGCGTGGAGGGCGACCCCCTCATCATGGTCTTTGAGTACATGAA
GCATGGGGACCTCAACAAGTTCCTCAGGGCACACGGCCCTGATGCCGTGCTGATGGCTGAGGGCAACCCGCCCACGGAACTGACGCAGTC
GCAGATGCTGCATATAGCCCAGCAGATCGCCGCGGGCATGGTCTACCTGGCGTCCCAGCACTTCGTGCACCGCGATTTGGCCACCAGGAA
CTGCCTGGTCGGGGAGAACTTGCTGGTGAAAATCGGGGACTTTGGGATGTCCCGGGACGTGTACAGCACTGACTACTACAGGGTCGGTGG
CCACACAATGCTGCCCATTCGCTGGATGCCTCCAGAGAGCATCATGTACAGGAAATTCACGACGGAAAGCGACGTCTGGAGCCTGGGGGT
CGTGTTGTGGGAGATTTTCACCTATGGCAAACAGCCCTGGTACCAGCTGTCAAACAATGAGGTGATAGAGTGTATCACTCAGGGCCGAGT
CCTGCAGCGACCCCGCACGTGCCCCCAGGAGGTGTATGAGCTGATGCTGGGGTGCTGGCAGCGAGAGCCCCACATGAGGAAGAACATCAA
GGGCATCCATACCCTCCTTCAGAACTTGGCCAAGGCATCTCCGGTCTACCTGGACATTCTAGGCTAGGGCCCTTTTCCCCAGACCGATCC
TTCCCAACGTACTCCTCAGACGGGCTGAGAGGATGAACATCTTTTAACTGCCGCTGGAGGCCACCAAGCTGCTCTCCTTCACTCTGACAG
TATTAACATCAAAGACTCCGAGAAGCTCTCGAGGGAAGCAGTGTGTACTTCTTCATCCATAGACACAGTATTGACTTCTTTTTGGCATTA
TCTCTTTCTCTCTTTCCATCTCCCTTGGTTGTTCCTTTTTCTTTTTTTAAATTTTCTTTTTCTTTTTTTTTTCGTCTTCCCTGCTTCACG
ATTCTTACCCTTTCTTTTGAATCAATCTGGCTTCTGCATTACTATTAACTCTGCATAGACAAAGGCCTTAACAAACGTAATTTGTTATAT
CAGCAGACACTCCAGTTTGCCCACCACAACTAACAATGCCTTGTTGTATTCCTGCCTTTGATGTGGATGAAAAAAAGGGAAAACAAATAT
TTCACTTAAACTTTGTCACTTCTGCTGTACAGATATCGAGAGTTTCTATGGATTCACTTCTATTTATTTATTATTATTACTGTTCTTATT
GTTTTTGGATGGCTTAAGCCTGTGTATAAAAAAGAAAACTTGTGTTCAATCTGTGAAGCCTTTATCTATGGGAGATTAAAACCAGAGAGA
AAGAAGATTTATTATGAACCGCAATATGGGAGGAACAAAGACAACCACTGGGATCAGCTGGTGTCAGTCCCTACTTAGGAAATACTCAGC
AACTGTTAGCTGGGAAGAATGTATTCGGCACCTTCCCCTGAGGACCTTTCTGAGGAGTAAAAAGACTACTGGCCTCTGTGCCATGGATGA
TTCTTTTCCCATCACCAGAAATGATAGCGTGCAGTAGAGAGCAAAGATGGCTTCCGTGAGACACAAGATGGCGCATAGTGTGCTCGGACA
CAGTTTTGTCTTCGTAGGTTGTGATGATAGCACTGGTTTGTTTCTCAAGCGCTATCCACAGAACCTTTGTCAACTTCAGTTGAAAAGAGG
TGGATTCATGTCCAGAGCTCATTTCGGGGTCAGGTGGGAAAGCCAAGAACTTGGAAAAGATAAGACAAGCTATAAATTCGGAGGCAAGTT
TCTTTTACAATGAACTTTTCAGATCTCACTTCCCTCCGACCCCTAACTTCCATGCCCACCCGTCCTTTTAACTGTGCAAGCAAAATTGTG
CATGGTCTTCGTCGATTAATACCTTGTGTGCAGACACTACTGCTCCAGACGTCGTTTCCCTGATAGGTAGAGCAGATCCATAAAAAGGTA
TGACTTATACAATTAGGGGAAGCTAATGGAGTTTATTAGCTGAGTATCAATGTCTCTGCGTTGTACGGTGGTGATGGGTTTTAATGAATA
TGGACCCTGAAGCCTGGAAATCCTCATCCACGTCGAACCCACAGGACTGTGGGAAGGGCAGAATCAATCCCTAAGGGAAAGGAAACCTCA
CCCTGAGGGCATCACATGCACTCATGTTCAGTGTACACAGGTCAAGTCCCTTGCTCTGGGCTCTAGTTGGGAGAGTGGTTTCATTCCAAG
TGTACTCCATTGTCAGTATGCTGTTTTTGTTTCCTTCACTCCATTCAAAAAGTCAAAATACAAAATTTGGCACAGCATGCCAACGGGAGG
CTGTGCCCAGACCAAGCACTGGAAGTGTGCTTCTAGGCATAGTCATTGGTTTTGCAAAAAGAGGGCTCAAATTTAAATAGAAATTTACAG
CTATTTGAATGGTCAGATATACCAAGAAAGAAAAATATTTCTGTTCCTCAAGAAAACTTGCTACCCTCTGTGAGGGGAATTTTGCTAAAC
TTGACATCTTTATAACATGAGCCAGATTGAAAGGGAGTGATTTTCATTCATCTTAGGTCATGTTATTTCATATTTGTTTCTGAAGGTGCG
ATAGCTCTGTTTTAGGTTTTGCTTGCGCCTGTTAATTACTGGAACACCTTATTTTTCATTAAAGGCTTTGAAAGCCAATTCTCAAAAATT
CAAAAGTGCAAATTAACAGAACAAAAGGAAATCCAGTAGCAACTGCAGTCAAGCGAGGGAGTTGACAAGATAAACCTTACGTCCATTCAA

>57095_57095_6_NACC2-NTRK2_NACC2_chr9_138905709_ENST00000277554_NTRK2_chr9_87359887_ENST00000376213_length(amino acids)=426AA_BP=2
MTDYGTAANDIGDTTNRSNEIPSTDVTDKTGREHLSVYAVVVIASVVGFCLLVMLFLLKLARHSKFGMKGPASVISNDDDSASPLHHISN
GSNTPSSSEGGPDAVIIGMTKIPVIENPQYFGITNSQLKPDTFVQHIKRHNIVLKRELGEGAFGKVFLAECYNLCPEQDKILVAVKTLKD
ASDNARKDFHREAELLTNLQHEHIVKFYGVCVEGDPLIMVFEYMKHGDLNKFLRAHGPDAVLMAEGNPPTELTQSQMLHIAQQIAAGMVY
LASQHFVHRDLATRNCLVGENLLVKIGDFGMSRDVYSTDYYRVGGHTMLPIRWMPPESIMYRKFTTESDVWSLGVVLWEIFTYGKQPWYQ

--------------------------------------------------------------
>57095_57095_7_NACC2-NTRK2_NACC2_chr9_138905709_ENST00000277554_NTRK2_chr9_87359887_ENST00000376214_length(transcript)=4788nt_BP=1313nt
AAAGTCCATGGGAGCCGGAGCGCCGGGACGCCAAGCACTTCCTGCCGCGGGCGGCGCGCCGCAGCTGCCCAGGCCGGACCGGGCCGGGCG
CCCGCAGATGAGCCCCGCTAGGGCCGCCCCGCGCTGAGAGCCCAGCCCCGCCGCTGCCCGCCCGCCATGTCTCAGATGCTGCACATCGAG
ATCCCCAACTTCGGGAACACAGTGCTGGGCTGCCTGAACGAGCAGCGCCTGCTGGGCCTCTACTGCGATGTGTCCATCGTGGTCAAGGGC
CAGGCCTTCAAGGCCCACCGGGCGGTGCTGGCCGCCAGCAGCCTCTACTTCCGCGACCTGTTCAGCGGCAACAGCAAGAGCGCCTTCGAG
CTGCCCGGCTCCGTGCCGCCCGCCTGCTTCCAGCAGATCCTGTCCTTCTGCTACACGGGCAGGCTCACCATGACGGCCAGCGAGCAGCTC
GTGGTCATGTACACGGCCGGCTTCCTGCAGATCCAGCACATCGTGGAGCGCGGCACCGACCTCATGTTCAAGGTGAGCTCGCCCCACTGC
GACTCGCAGACCGCTGTGATCGAGGACGCCGGCTCCGAGCCCCAGAGCCCCTGCAACCAGCTGCAGCCGGCCGCCGCCGCCGCGGCCCCC
TACGTCGTGTCCCCCTCGGTGCCCATCCCGCTGCTGACCCGAGTAAAGCATGAAGCCATGGAGCTGCCGCCGGCCGGCCCAGGCCTGGCC
CCCAAGCGCCCGCTGGAGACGGGGCCCCGGGACGGCGTGGCGGTGGCCGCGGGGGCTGCGGTGGCGGCGGGCACAGCCCCTCTCAAACTG
CCCCGTGTCTCCTACTACGGGGTGCCCAGCCTGGCCACCCTCATCCCCGGCATCCAGCAGATGCCCTACCCCCAGGGGGAGCGGACCAGT
CCAGGCGCCAGCAGCCTGCCCACCACCGACAGCCCCACCTCGTACCACAACGAGGAGGACGAGGAGGACGACGAGGCCTACGACACCATG
GTGGAGGAGCAGTACGGCCAGATGTACATCAAGGCCTCCGGCAGCTATGCAGTGCAAGAGAAGCCTGAGCCAGTGCCGCTGGAGAGCCGC
TCCTGCGTCCTCATCCGCCGCGACCTCGTGGCCCTACCTGCCAGCCTCATCAGCCAGATCGGATACCGCTGCCATCCCAAGCTCTACTCG
GAAGGGGACCCCGGGGAGAAGCTGGAGCTGGTGGCAGGCTCTGGGGTCTACATCACACGCGGCCAGCTGATGAACTGCCACCTGTGTGCA
GGGGTGAAGCATAAGGTCTTGCTGCGGAGGCTCCTGGCCACCTTCTTTGACAGATTATGGAACTGCAGCGAATGACATCGGGGACACCAC
GAACAGAAGTAATGAAATCCCTTCCACAGACGTCACTGATAAAACCGGTCGGGAACATCTCTCGGTCTATGCTGTGGTGGTGATTGCGTC
TGTGGTGGGATTTTGCCTTTTGGTAATGCTGTTTCTGCTTAAGTTGGCAAGACACTCCAAGTTTGGCATGAAAGATTTCTCATGGTTTGG
ATTTGGGAAAGTAAAATCAAGACAAGGTGTTGGCCCAGCCTCCGTTATCAGCAATGATGATGACTCTGCCAGCCCACTCCATCACATCTC
CAATGGGAGTAACACTCCATCTTCTTCGGAAGGTGGCCCAGATGCTGTCATTATTGGAATGACCAAGATCCCTGTCATTGAAAATCCCCA
GTACTTTGGCATCACCAACAGTCAGCTCAAGCCAGACACATTTGTTCAGCACATCAAGCGACATAACATTGTTCTGAAAAGGGAGCTAGG
CGAAGGAGCCTTTGGAAAAGTGTTCCTAGCTGAATGCTATAACCTCTGTCCTGAGCAGGACAAGATCTTGGTGGCAGTGAAGACCCTGAA
GGATGCCAGTGACAATGCACGCAAGGACTTCCACCGTGAGGCCGAGCTCCTGACCAACCTCCAGCATGAGCACATCGTCAAGTTCTATGG
CGTCTGCGTGGAGGGCGACCCCCTCATCATGGTCTTTGAGTACATGAAGCATGGGGACCTCAACAAGTTCCTCAGGGCACACGGCCCTGA
TGCCGTGCTGATGGCTGAGGGCAACCCGCCCACGGAACTGACGCAGTCGCAGATGCTGCATATAGCCCAGCAGATCGCCGCGGGCATGGT
CTACCTGGCGTCCCAGCACTTCGTGCACCGCGATTTGGCCACCAGGAACTGCCTGGTCGGGGAGAACTTGCTGGTGAAAATCGGGGACTT
TGGGATGTCCCGGGACGTGTACAGCACTGACTACTACAGGGTCGGTGGCCACACAATGCTGCCCATTCGCTGGATGCCTCCAGAGAGCAT
CATGTACAGGAAATTCACGACGGAAAGCGACGTCTGGAGCCTGGGGGTCGTGTTGTGGGAGATTTTCACCTATGGCAAACAGCCCTGGTA
CCAGCTGTCAAACAATGAGGTGATAGAGTGTATCACTCAGGGCCGAGTCCTGCAGCGACCCCGCACGTGCCCCCAGGAGGTGTATGAGCT
GATGCTGGGGTGCTGGCAGCGAGAGCCCCACATGAGGAAGAACATCAAGGGCATCCATACCCTCCTTCAGAACTTGGCCAAGGCATCTCC
GGTCTACCTGGACATTCTAGGCTAGGGCCCTTTTCCCCAGACCGATCCTTCCCAACGTACTCCTCAGACGGGCTGAGAGGATGAACATCT
TTTAACTGCCGCTGGAGGCCACCAAGCTGCTCTCCTTCACTCTGACAGTATTAACATCAAAGACTCCGAGAAGCTCTCGAGGGAAGCAGT
GTGTACTTCTTCATCCATAGACACAGTATTGACTTCTTTTTGGCATTATCTCTTTCTCTCTTTCCATCTCCCTTGGTTGTTCCTTTTTCT
TTTTTTAAATTTTCTTTTTCTTTTTTTTTTCGTCTTCCCTGCTTCACGATTCTTACCCTTTCTTTTGAATCAATCTGGCTTCTGCATTAC
TATTAACTCTGCATAGACAAAGGCCTTAACAAACGTAATTTGTTATATCAGCAGACACTCCAGTTTGCCCACCACAACTAACAATGCCTT
GTTGTATTCCTGCCTTTGATGTGGATGAAAAAAAGGGAAAACAAATATTTCACTTAAACTTTGTCACTTCTGCTGTACAGATATCGAGAG
TTTCTATGGATTCACTTCTATTTATTTATTATTATTACTGTTCTTATTGTTTTTGGATGGCTTAAGCCTGTGTATAAAAAAGAAAACTTG
TGTTCAATCTGTGAAGCCTTTATCTATGGGAGATTAAAACCAGAGAGAAAGAAGATTTATTATGAACCGCAATATGGGAGGAACAAAGAC
AACCACTGGGATCAGCTGGTGTCAGTCCCTACTTAGGAAATACTCAGCAACTGTTAGCTGGGAAGAATGTATTCGGCACCTTCCCCTGAG
GACCTTTCTGAGGAGTAAAAAGACTACTGGCCTCTGTGCCATGGATGATTCTTTTCCCATCACCAGAAATGATAGCGTGCAGTAGAGAGC
AAAGATGGCTTCCGTGAGACACAAGATGGCGCATAGTGTGCTCGGACACAGTTTTGTCTTCGTAGGTTGTGATGATAGCACTGGTTTGTT
TCTCAAGCGCTATCCACAGAACCTTTGTCAACTTCAGTTGAAAAGAGGTGGATTCATGTCCAGAGCTCATTTCGGGGTCAGGTGGGAAAG
CCAAGAACTTGGAAAAGATAAGACAAGCTATAAATTCGGAGGCAAGTTTCTTTTACAATGAACTTTTCAGATCTCACTTCCCTCCGACCC
CTAACTTCCATGCCCACCCGTCCTTTTAACTGTGCAAGCAAAATTGTGCATGGTCTTCGTCGATTAATACCTTGTGTGCAGACACTACTG
CTCCAGACGTCGTTTCCCTGATAGGTAGAGCAGATCCATAAAAAGGTATGACTTATACAATTAGGGGAAGCTAATGGAGTTTATTAGCTG
AGTATCAATGTCTCTGCGTTGTACGGTGGTGATGGGTTTTAATGAATATGGACCCTGAAGCCTGGAAATCCTCATCCACGTCGAACCCAC
AGGACTGTGGGAAGGGCAGAATCAATCCCTAAGGGAAAGGAAACCTCACCCTGAGGGCATCACATGCACTCATGTTCAGTGTACACAGGT
CAAGTCCCTTGCTCTGGGCTCTAGTTGGGAGAGTGGTTTCATTCCAAGTGTACTCCATTGTCAGTATGCTGTTTTTGTTTCCTTCACTCC
ATTCAAAAAGTCAAAATACAAAATTTGGCACAGCATGCCAACGGGAGGCTGTGCCCAGACCAAGCACTGGAAGTGTGCTTCTAGGCATAG
TCATTGGTTTTGCAAAAAGAGGGCTCAAATTTAAATAGAAATTTACAGCTATTTGAATGGTCAGATATACCAAGAAAGAAAAATATTTCT
GTTCCTCAAGAAAACTTGCTACCCTCTGTGAGGGGAATTTTGCTAAACTTGACATCTTTATAACATGAGCCAGATTGAAAGGGAGTGATT
TTCATTCATCTTAGGTCATGTTATTTCATATTTGTTTCTGAAGGTGCGATAGCTCTGTTTTAGGTTTTGCTTGCGCCTGTTAATTACTGG
AACACCTTATTTTTCATTAAAGGCTTTGAAAGCCAATTCTCAAAAATTCAAAAGTGCAAATTAACAGAACAAAAGGAAATCCAGTAGCAA
CTGCAGTCAAGCGAGGGAGTTGACAAGATAAACCTTACGTCCATTCAAGTTATATGCTGGCCTATGAGAGATGAGAGTTGGGTCGTTTGT

>57095_57095_7_NACC2-NTRK2_NACC2_chr9_138905709_ENST00000277554_NTRK2_chr9_87359887_ENST00000376214_length(amino acids)=442AA_BP=2
MTDYGTAANDIGDTTNRSNEIPSTDVTDKTGREHLSVYAVVVIASVVGFCLLVMLFLLKLARHSKFGMKDFSWFGFGKVKSRQGVGPASV
ISNDDDSASPLHHISNGSNTPSSSEGGPDAVIIGMTKIPVIENPQYFGITNSQLKPDTFVQHIKRHNIVLKRELGEGAFGKVFLAECYNL
CPEQDKILVAVKTLKDASDNARKDFHREAELLTNLQHEHIVKFYGVCVEGDPLIMVFEYMKHGDLNKFLRAHGPDAVLMAEGNPPTELTQ
SQMLHIAQQIAAGMVYLASQHFVHRDLATRNCLVGENLLVKIGDFGMSRDVYSTDYYRVGGHTMLPIRWMPPESIMYRKFTTESDVWSLG

--------------------------------------------------------------
>57095_57095_8_NACC2-NTRK2_NACC2_chr9_138905709_ENST00000277554_NTRK2_chr9_87359887_ENST00000395866_length(transcript)=2036nt_BP=1313nt
AAAGTCCATGGGAGCCGGAGCGCCGGGACGCCAAGCACTTCCTGCCGCGGGCGGCGCGCCGCAGCTGCCCAGGCCGGACCGGGCCGGGCG
CCCGCAGATGAGCCCCGCTAGGGCCGCCCCGCGCTGAGAGCCCAGCCCCGCCGCTGCCCGCCCGCCATGTCTCAGATGCTGCACATCGAG
ATCCCCAACTTCGGGAACACAGTGCTGGGCTGCCTGAACGAGCAGCGCCTGCTGGGCCTCTACTGCGATGTGTCCATCGTGGTCAAGGGC
CAGGCCTTCAAGGCCCACCGGGCGGTGCTGGCCGCCAGCAGCCTCTACTTCCGCGACCTGTTCAGCGGCAACAGCAAGAGCGCCTTCGAG
CTGCCCGGCTCCGTGCCGCCCGCCTGCTTCCAGCAGATCCTGTCCTTCTGCTACACGGGCAGGCTCACCATGACGGCCAGCGAGCAGCTC
GTGGTCATGTACACGGCCGGCTTCCTGCAGATCCAGCACATCGTGGAGCGCGGCACCGACCTCATGTTCAAGGTGAGCTCGCCCCACTGC
GACTCGCAGACCGCTGTGATCGAGGACGCCGGCTCCGAGCCCCAGAGCCCCTGCAACCAGCTGCAGCCGGCCGCCGCCGCCGCGGCCCCC
TACGTCGTGTCCCCCTCGGTGCCCATCCCGCTGCTGACCCGAGTAAAGCATGAAGCCATGGAGCTGCCGCCGGCCGGCCCAGGCCTGGCC
CCCAAGCGCCCGCTGGAGACGGGGCCCCGGGACGGCGTGGCGGTGGCCGCGGGGGCTGCGGTGGCGGCGGGCACAGCCCCTCTCAAACTG
CCCCGTGTCTCCTACTACGGGGTGCCCAGCCTGGCCACCCTCATCCCCGGCATCCAGCAGATGCCCTACCCCCAGGGGGAGCGGACCAGT
CCAGGCGCCAGCAGCCTGCCCACCACCGACAGCCCCACCTCGTACCACAACGAGGAGGACGAGGAGGACGACGAGGCCTACGACACCATG
GTGGAGGAGCAGTACGGCCAGATGTACATCAAGGCCTCCGGCAGCTATGCAGTGCAAGAGAAGCCTGAGCCAGTGCCGCTGGAGAGCCGC
TCCTGCGTCCTCATCCGCCGCGACCTCGTGGCCCTACCTGCCAGCCTCATCAGCCAGATCGGATACCGCTGCCATCCCAAGCTCTACTCG
GAAGGGGACCCCGGGGAGAAGCTGGAGCTGGTGGCAGGCTCTGGGGTCTACATCACACGCGGCCAGCTGATGAACTGCCACCTGTGTGCA
GGGGTGAAGCATAAGGTCTTGCTGCGGAGGCTCCTGGCCACCTTCTTTGACAGATTATGGAACTGCAGCGAATGACATCGGGGACACCAC
GAACAGAAGTAATGAAATCCCTTCCACAGACGTCACTGATAAAACCGGTCGGGAACATCTCTCGGTCTATGCTGTGGTGGTGATTGCGTC
TGTGGTGGGATTTTGCCTTTTGGTAATGCTGTTTCTGCTTAAGTTGGCAAGACACTCCAAGTTTGGCATGAAAGGTTTTGTTTTGTTTCA
TAAGATCCCACTGGATGGGTAGCTGAAATAAAGGAAAAGACAGAGAAAGGGGCTGTGGTGCTTGTTGGTTGATGCTGCCATGTAAGCTGG
ACTCCTGGGACTGCTGTTGGCTTATCCCGGGAAGTGCTGCTTATCTGGGGTTTTCTGGTAGATGTGGGCGGTGTTTGGAGGCTGTACTAT
ATGAAGCCTGCATATACTGTGAGCTGTGATTGGGGAACACCAATGCAGAGGTAACTCTCAGGCAGCTAAGCAGCACCTCAAGAAAACATG
TTAAATTAATGCTTCTCTTCTTACAGTAGTTCAAATACAAAACTGAAATGAAATCCCATTGGATTGTACTTCTCTTCTGAAAAGTGTGCT
TTTTGACCCTACTGGACATTTATTGACTTAATTGCTTCTGTTTATTAAAATTGACCTGCAAAGTTAAAAAAAAATTAAAGTTGAGAACAG

>57095_57095_8_NACC2-NTRK2_NACC2_chr9_138905709_ENST00000277554_NTRK2_chr9_87359887_ENST00000395866_length(amino acids)=403AA_BP=
MRAQPRRCPPAMSQMLHIEIPNFGNTVLGCLNEQRLLGLYCDVSIVVKGQAFKAHRAVLAASSLYFRDLFSGNSKSAFELPGSVPPACFQ
QILSFCYTGRLTMTASEQLVVMYTAGFLQIQHIVERGTDLMFKVSSPHCDSQTAVIEDAGSEPQSPCNQLQPAAAAAAPYVVSPSVPIPL
LTRVKHEAMELPPAGPGLAPKRPLETGPRDGVAVAAGAAVAAGTAPLKLPRVSYYGVPSLATLIPGIQQMPYPQGERTSPGASSLPTTDS
PTSYHNEEDEEDDEAYDTMVEEQYGQMYIKASGSYAVQEKPEPVPLESRSCVLIRRDLVALPASLISQIGYRCHPKLYSEGDPGEKLELV

--------------------------------------------------------------
>57095_57095_9_NACC2-NTRK2_NACC2_chr9_138905709_ENST00000277554_NTRK2_chr9_87359887_ENST00000395882_length(transcript)=6679nt_BP=1313nt
AAAGTCCATGGGAGCCGGAGCGCCGGGACGCCAAGCACTTCCTGCCGCGGGCGGCGCGCCGCAGCTGCCCAGGCCGGACCGGGCCGGGCG
CCCGCAGATGAGCCCCGCTAGGGCCGCCCCGCGCTGAGAGCCCAGCCCCGCCGCTGCCCGCCCGCCATGTCTCAGATGCTGCACATCGAG
ATCCCCAACTTCGGGAACACAGTGCTGGGCTGCCTGAACGAGCAGCGCCTGCTGGGCCTCTACTGCGATGTGTCCATCGTGGTCAAGGGC
CAGGCCTTCAAGGCCCACCGGGCGGTGCTGGCCGCCAGCAGCCTCTACTTCCGCGACCTGTTCAGCGGCAACAGCAAGAGCGCCTTCGAG
CTGCCCGGCTCCGTGCCGCCCGCCTGCTTCCAGCAGATCCTGTCCTTCTGCTACACGGGCAGGCTCACCATGACGGCCAGCGAGCAGCTC
GTGGTCATGTACACGGCCGGCTTCCTGCAGATCCAGCACATCGTGGAGCGCGGCACCGACCTCATGTTCAAGGTGAGCTCGCCCCACTGC
GACTCGCAGACCGCTGTGATCGAGGACGCCGGCTCCGAGCCCCAGAGCCCCTGCAACCAGCTGCAGCCGGCCGCCGCCGCCGCGGCCCCC
TACGTCGTGTCCCCCTCGGTGCCCATCCCGCTGCTGACCCGAGTAAAGCATGAAGCCATGGAGCTGCCGCCGGCCGGCCCAGGCCTGGCC
CCCAAGCGCCCGCTGGAGACGGGGCCCCGGGACGGCGTGGCGGTGGCCGCGGGGGCTGCGGTGGCGGCGGGCACAGCCCCTCTCAAACTG
CCCCGTGTCTCCTACTACGGGGTGCCCAGCCTGGCCACCCTCATCCCCGGCATCCAGCAGATGCCCTACCCCCAGGGGGAGCGGACCAGT
CCAGGCGCCAGCAGCCTGCCCACCACCGACAGCCCCACCTCGTACCACAACGAGGAGGACGAGGAGGACGACGAGGCCTACGACACCATG
GTGGAGGAGCAGTACGGCCAGATGTACATCAAGGCCTCCGGCAGCTATGCAGTGCAAGAGAAGCCTGAGCCAGTGCCGCTGGAGAGCCGC
TCCTGCGTCCTCATCCGCCGCGACCTCGTGGCCCTACCTGCCAGCCTCATCAGCCAGATCGGATACCGCTGCCATCCCAAGCTCTACTCG
GAAGGGGACCCCGGGGAGAAGCTGGAGCTGGTGGCAGGCTCTGGGGTCTACATCACACGCGGCCAGCTGATGAACTGCCACCTGTGTGCA
GGGGTGAAGCATAAGGTCTTGCTGCGGAGGCTCCTGGCCACCTTCTTTGACAGATTATGGAACTGCAGCGAATGACATCGGGGACACCAC
GAACAGAAGTAATGAAATCCCTTCCACAGACGTCACTGATAAAACCGGTCGGGAACATCTCTCGGTCTATGCTGTGGTGGTGATTGCGTC
TGTGGTGGGATTTTGCCTTTTGGTAATGCTGTTTCTGCTTAAGTTGGCAAGACACTCCAAGTTTGGCATGAAAGGTTTTGTTTTGTTTCA
TAAGATCCCACTGGATGGGTAGCTGAAATAAAGGAAAAGACAGAGAAAGGGGCTGTGGTGCTTGTTGGTTGATGCTGCCATGTAAGCTGG
ACTCCTGGGACTGCTGTTGGCTTATCCCGGGAAGTGCTGCTTATCTGGGGTTTTCTGGTAGATGTGGGCGGTGTTTGGAGGCTGTACTAT
ATGAAGCCTGCATATACTGTGAGCTGTGATTGGGGAACACCAATGCAGAGGTAACTCTCAGGCAGCTAAGCAGCACCTCAAGAAAACATG
TTAAATTAATGCTTCTCTTCTTACAGTAGTTCAAATACAAAACTGAAATGAAATCCCATTGGATTGTACTTCTCTTCTGAAAAGTGTGCT
TTTTGACCCTACTGGACATTTATTGACTTAATTGCTTCTGTTTATTAAAATTGACCTGCAAAGTTAAAAAAAAATTAAAGTTGAGAACAG
GTATAAGTGCACACTGAATAGTCTAATCTACATGTAACACATATTTTAGTGTGATTTTCTATACTCTAATCAGCACTGAATTCAGAGGGT
TTGACTTTTTCATCTATAACACAGTGACTAAAAGAGTTAAGGGTATATATACCATCACTTTGGGACTTGGTAGTATTATTAAAAGGTTAT
TTCCTTCACTGTCAATAAAAGTCCAAATGTTTAGCTTAGGTCTGAGAGTCAAACAATGTTAAGGATTGTCTTAAAGTTCCTTAGCCAGCA
AAACAAAACAAAACAAAACAAACAAATGAAAAACGTTTAAAAAGAAGAAGAAGAAAAAAAACAAGAACAAGCAGCAACAGCTGTTTTGTT
GGGGCTATAGATTTAAGTTAGGCATAGTCAATTTCAGAATAACTAAGAGTGGAATATATGCATATGGTGAAATTATAACCTTGCCCTTTT
TTATTTGCCCTCTGCGATCCACCTGCTTTTTAGAAGTCTGCCGAGTGAGAAGGCCACAGTATCTCATGCTGTTTGCATTACAGAACTGCA
GCTTTTCTACTCTGAAAAGGCCTGGGAGCAGAATGGCTGGCCTGCTGTGAGCAGGAGAGGAGATTCTAAGAAGGATAGTCCCCCCTACAA
CATACTGTCATACTGCTGGGTTTTCATGGGTAGGAAAGCTTGTCCTGACCCCAGCAGCAAAGAGGTGGCAGGTCGCTAATGAATATATGC
TTTATAATGTCCTTCTTCATTGCTGAGAGGGCAGCCTTAGAGCTGTGGATTTCTGCATCCCCCCTGAGTCTGACCCATGGACACCTGTTT
CATTCACTTTAGCATCACAGTGACCTTTGTATGCTCTGTTCAGTCTGTGTCAGGCAGTATGCTTGTCCTGAAGAGAGGTTTGGCTATCCC
CACCCCACCCCACCCCACCCTGTTCCTTTTTTATCAGGAGGACTTCAGAGCCAGGCCTGCAGCATTTTGTTTGAAAACACAATCAGCTCT
GACAGTTAGACATGCACACAGACGCCATAGCTGGATTGGAAACATTGATGTTTTAAAAATTTATTTTTTTTGGAAATAGTTGCACAAATG
CTGCAATTTAGCTTTAAGGTTCTATAGATTTTTAACTAGTCCAACACAGTCAGAAACATTGTTTTGAATCCTCTGTAAACCAAGGCATTA
ATCTTAATAAACCAGGATCCATTTAGGTACCACTTGATATAAAAAGGATATCCATAATGAATATTTTATACTGCATCCTTTACATTAGCC
ACTAAATACGTTATTGCTTGATGAAGACCTTTCACAGAATCCTATGGATTGCAGCATTTCACTTGGCTACTTCATACCCATGCCTTAAAG
AGGGGCAGTTTCTCAAAAGCAGAAACATGCCGCCAGTTCTCAAGTTTTCCTCCTAACTCCATTTGAATGTAAGGGCAGCTGGCCCCCAAT
GTGGGGAGGTCCGAACATTTTCTGAATTCCCATTTTCTTGTTCGCGGCTAAATGACAGTTTCTGTCATTACTTAGATTCCGATCTTTCCC
AAAGGTGTTGATTTACAAAGAGGCCAGCTAATAGCAGAAATCATGACCCTGAAAGAGAGATGAAATTCAAGCTGTGAGCCAGGCAGGAGC
TCAGTATGGCAAAGGTTCTTGAGAATCAGCCATTTGGTACAAAAAAGATTTTTAAAGCTTTTATGTTATACCATGGAGCCATAGAAAGGC
TATGGATTGTTTAAGAACTATTTTAAAGTGTTCCAGACCCAAAAAGGAAAAATAAAAAAAAAGGAATATTTGTACCCAACAGCTAGAAGG
ATTGCAAGGTAGATTTTTGTTTTAAAATGGAGAGAAGTGGACAGATAAGGCCATTTAATATATCAAAGATCAGTTGACATCTCCTAGGGA
ATGATGAAAACAGCAGGCTATTAGAAAATTATTTCATATAGTTCTCGTGTTCTTTTCTTTTTTTTAATCCCTGAAGGGATGATCAGTAAC
ATAGCTTCTCTTTTCTGTACTCTAGACCACCCCTTTTCATCATTTTGCTTTTTATGTCTCCCATAAGAAATGTGCTTTTTAGAGCTTCCT
AATGCATGTGTTGCATTATTGCAGCATTAGAAAAGGAGAGGTAGCATTTTTGCTGAAATCGGGCCTGTCACTCTCCAATAAAGGTTCTGG
CACTTCAATGCCAGGCAGGTCTCCTAAATGAACAGAATGATCTGTGTGAGCCGATGCCTGCCCTTCCAGAGGGGCCACTGTCCCCAGCCG
CAGCCAACTGTGTCCCACAGGAATGGGAGCCTAGGTTTCCAAATCTTGTGATTCTTTAGGAGAAACATGAAACCTGGATTTCGTGTGAAA
TGTCCCGATTGTTAAAAAGTTGGCTCAATTATTTTTAAAACATTTTGTAAGCCAACAAAAGTCTGTGGGCTGCCAGTTTATTACTTTTGT
CTTAAAACATGATCATTGTTCTCTCACGGTATCCTTCTGTCTTCCCGTTGCAAATTCACTTTTCTTTCTTCCTGACATTGCCATTGAGGG
CTTTGTTACCACAAGCTAAGAAACTGAGTTTAACAGCCCAGTTATCTGCAACATGTCAATTACCTTTGCTCCTCTCCTGTGATTCCCACC
ATGCTGTGACCCTCAGCTGTCTCCCTTTGCTGGGAATTCTGCACCAATGTCTCCCCTCAACCCATTCCCTGGTTGGTCCTACTCCCGTGT
GGCCAGAGACATCCTAGCAAATCCTTCCTCCTATTATATCTGACACTAATTTCTTTTCAACAGCGCTCATGTCTCTTGGCCCAGTCAGGT
GCTGCCAGGTTTAGATAGGAAAGTACATGTCCCATTTTCATGGGTGCCCTTAATGTGGTCCACGTCCTATATCTTATTATATTTACTCAT
GGCTCAATGGGGGCCTCCAGAGACCCTCTCAGGCTGCTGAGCTAGACTAAGGAATGCATCCACCGTCATCACATGAGACACTGACTCTGT
GACGACAAAAGTACAAACAGTCTGAGGCTAAGAAAGGTTCATCTCACAACAGGAAAAACAAATCTCAACACACATTAGAGATAATTGATT
CAGGGGTTTTCTCTCCCAGTCTCCCAGCAGGGACTGATTTCATTTCTGACCCACTAGGTTTTCTTTCCAGAAATAGGTAGCAAGGACAAG
AACTAAACAATCCCAGCCCCACCCAGCAACACAGAACACAGGAGTTTGCTTTTGGCTTCTCACTCTCCAAGTAACCCTGAATTAGGCCCA
GAATGGCTGAGGCTTGGAGCATCTCCTCAGACAGAGCAGAGGCGACACCTCTTCAGGGGTGTGTGGAGTAAATAGCTCGAAGAGCTGAAG
ACAGAAAACCAGTTTCACGCCAGGTGCGAGAGAGAGCATAATGGAGGGAAGCCCGCTTTCTCTCTCCTCTTCTTTTCTCTTTATTTCTTT
AGAGCACTTGACTTTTTTTTCTCTCTCTCTCTAGTATTCTAAACTGACCCCATGACCAACTGAGAATTTATTTTTGTTTCATTGGTTGTT
TCACAGAATTAGAACACACACGACTTTTTATTCCTCCATTGCAAAATGGAATCAAGATACTACACAAGACCTGTGCTTTCTTCCTTTGCA
TGATTTACACCTCCGCCTGTTTTGGTGCTAGCTGTCTAGAACTTCTCTCTTGGTTTGAATCTGATTCCTTCACACTACACTAGAAGTTTA
TTTCATCTTGTTTTGTCTAGACTCCAGATACAGAGGGACAGCTGGACTGAGGACAAGCAATTCCATCTAGCATAGGGTCTCTCAGGGTTG
GTGCATCCAGCCACATGGGCAGGGCCAGTCACATCTAGTCTATGTCCCCAGAGCCCTTGGAGTTGCGCAGCTTAGCTGACTTGACTCCAA
GGAAATTAGTACAGAAGTAACCACTCTATTAAGTGTGTTCTGCTATGTTCACATGCCTGTAGTACCTGCAAACCATGCCAGGTTCATCTA
AAGACATAGGGGAAGATTAAGGACTCTTTTGGACAGACCATGAATTGAATTTGCTGCCAGGTGCTGCCAGACTGAATTTGGCTGACAGAA
CTCCCAGCCCAGGAAAGTTCCATGACAATGACTGTCGCAGAAGGAAATTTCCCACTAAAGTCAGTCCATTTTCAAGTTTTGGTCTTCAGA
GACAAAAGAACGTCCCAGCCACCTGATTTTGATGGTGAGGTAACTCTAAGTTGAATTCAGGCTAGTGTTGCAGTATAGCTTTGGCATGTT
CATGAGTGAGCACCCAGAATGTGTTGAACCAACCCCCACCCCTAACTACTGACTATGACTGCAGTGGGTTTTTATGGGGAAAAAAAGTGT
GAAAAGCAAAAAGAAAGGAACAGAGATTTTTTATCACCTTTATTGTAAGACAGTCCATTTATGAATTGAGTATAAACACATACAAAGTAA
CAAGAGATTCCTAAGAAACGCAAATCCTTGAGTTTCACGCACTTCATGTTCAACCATTTGCTGTAATCCAGAGGCAGCCTGTGAATCATT
CTCATGCCCTGTTTTTTTTTTTTTTTTCCTATAATGTTCTGGGTTTAAAAGCCATCTTTTCCACATTTTCTGTAAATAATGGATAATCAT
TTTAAAAATTTTTATTTTTAGTGCTGTTTTAACAATGTAGATAGATCATAAATGTACTTGCTGAATTCAATCATTTTTAACAAGCCAATA

>57095_57095_9_NACC2-NTRK2_NACC2_chr9_138905709_ENST00000277554_NTRK2_chr9_87359887_ENST00000395882_length(amino acids)=403AA_BP=
MRAQPRRCPPAMSQMLHIEIPNFGNTVLGCLNEQRLLGLYCDVSIVVKGQAFKAHRAVLAASSLYFRDLFSGNSKSAFELPGSVPPACFQ
QILSFCYTGRLTMTASEQLVVMYTAGFLQIQHIVERGTDLMFKVSSPHCDSQTAVIEDAGSEPQSPCNQLQPAAAAAAPYVVSPSVPIPL
LTRVKHEAMELPPAGPGLAPKRPLETGPRDGVAVAAGAAVAAGTAPLKLPRVSYYGVPSLATLIPGIQQMPYPQGERTSPGASSLPTTDS
PTSYHNEEDEEDDEAYDTMVEEQYGQMYIKASGSYAVQEKPEPVPLESRSCVLIRRDLVALPASLISQIGYRCHPKLYSEGDPGEKLELV

--------------------------------------------------------------

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Fusion Gene PPI Analysis for NACC2-NTRK2


check button Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in

ChiPPI page.


check button Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160)
HgeneHgene's interactorsTgeneTgene's interactors


check button - Retained PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenStill interaction with


check button - Lost PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


check button - Retained PPIs, but lost function due to frame-shift fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


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Related Drugs for NACC2-NTRK2


check button Drugs targeting genes involved in this fusion gene.
(DrugBank Version 5.1.8 2021-05-08)
PartnerGeneUniProtAccDrugBank IDDrug nameDrug activityDrug typeDrug status

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Related Diseases for NACC2-NTRK2


check button Diseases associated with fusion partners.
(DisGeNet 4.0)
PartnerGeneDisease IDDisease name# pubmedsSource