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Center for Computational Systems Medicine
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Fusion Gene Summary

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Fusion Gene ORF analysis

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Fusion Genomic Features

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Fusion Protein Features

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Fusion Gene Sequence

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Fusion Gene PPI analysis

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Related Drugs

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Related Diseases

Fusion gene:NADSYN1-SPAG9 (FusionGDB2 ID:57135)

Fusion Gene Summary for NADSYN1-SPAG9

check button Fusion gene summary
Fusion gene informationFusion gene name: NADSYN1-SPAG9
Fusion gene ID: 57135
HgeneTgene
Gene symbol

NADSYN1

SPAG9

Gene ID

55191

9043

Gene nameNAD synthetase 1sperm associated antigen 9
Synonyms-CT89|HLC-6|HLC4|HLC6|JIP-4|JIP4|JLP|PHET|PIG6
Cytomap

11q13.4

17q21.33

Type of geneprotein-codingprotein-coding
Descriptionglutamine-dependent NAD(+) synthetaseNAD(+) synthaseNAD(+) synthetaseglutamine-dependent NAD synthetaseC-Jun-amino-terminal kinase-interacting protein 4JNK interacting proteinJNK/SAPK-associated proteinMax-binding proteinc-Jun NH2-terminal kinase-associated leucine zipper proteincancer/testis antigen 89human lung cancer oncogene 6 proteinlung cancer
Modification date2020031320200315
UniProtAcc..
Ensembl transtripts involved in fusion geneENST00000526039, ENST00000319023, 
ENST00000530055, ENST00000539574, 
ENST00000262013, ENST00000357122, 
ENST00000505279, ENST00000509724, 
ENST00000510283, 
Fusion gene scores* DoF score14 X 13 X 7=127415 X 14 X 6=1260
# samples 1716
** MAII scorelog2(17/1274*10)=-2.9057586261186
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0		log2(16/1260*10)=-2.97727992349992
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0
Context

PubMed: NADSYN1 [Title/Abstract] AND SPAG9 [Title/Abstract] AND fusion [Title/Abstract]

Most frequent breakpointNADSYN1(71193071)-SPAG9(49048217), # samples:3
Anticipated loss of major functional domain due to fusion event.
* DoF score (Degree of Frequency) = # partners X # break points X # cancer types
** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)

check button Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez
PartnerGeneGO IDGO termPubMed ID
TgeneSPAG9

GO:0042147

retrograde transport, endosome to Golgi

19056739


check buttonFusion gene breakpoints across NADSYN1 (5'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check buttonFusion gene breakpoints across SPAG9 (3'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check button Fusion gene information from two resources (ChiTars 5.0 and ChimerDB 4.0)
* All genome coordinats were lifted-over on hg19.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
SourceDiseaseSampleHgeneHchrHbpHstrandTgeneTchrTbpTstrand
ChimerDB4ESCATCGA-L5-A43I-01ANADSYN1chr11

71193071

-SPAG9chr17

49048217

-
ChimerDB4ESCATCGA-L5-A43I-01ANADSYN1chr11

71193071

+SPAG9chr17

49048217

-
ChimerDB4ESCATCGA-L5-A43INADSYN1chr11

71193071

+SPAG9chr17

49048217

-


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Fusion Gene ORF analysis for NADSYN1-SPAG9

check button Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
ORFHenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrand
3UTR-3CDSENST00000526039ENST00000262013NADSYN1chr11

71193071

+SPAG9chr17

49048217

-
3UTR-3CDSENST00000526039ENST00000357122NADSYN1chr11

71193071

+SPAG9chr17

49048217

-
3UTR-3CDSENST00000526039ENST00000505279NADSYN1chr11

71193071

+SPAG9chr17

49048217

-
3UTR-intronENST00000526039ENST00000509724NADSYN1chr11

71193071

+SPAG9chr17

49048217

-
3UTR-intronENST00000526039ENST00000510283NADSYN1chr11

71193071

+SPAG9chr17

49048217

-
5CDS-intronENST00000319023ENST00000509724NADSYN1chr11

71193071

+SPAG9chr17

49048217

-
5CDS-intronENST00000319023ENST00000510283NADSYN1chr11

71193071

+SPAG9chr17

49048217

-
5CDS-intronENST00000530055ENST00000509724NADSYN1chr11

71193071

+SPAG9chr17

49048217

-
5CDS-intronENST00000530055ENST00000510283NADSYN1chr11

71193071

+SPAG9chr17

49048217

-
5CDS-intronENST00000539574ENST00000509724NADSYN1chr11

71193071

+SPAG9chr17

49048217

-
5CDS-intronENST00000539574ENST00000510283NADSYN1chr11

71193071

+SPAG9chr17

49048217

-
In-frameENST00000319023ENST00000262013NADSYN1chr11

71193071

+SPAG9chr17

49048217

-
In-frameENST00000319023ENST00000357122NADSYN1chr11

71193071

+SPAG9chr17

49048217

-
In-frameENST00000319023ENST00000505279NADSYN1chr11

71193071

+SPAG9chr17

49048217

-
In-frameENST00000530055ENST00000262013NADSYN1chr11

71193071

+SPAG9chr17

49048217

-
In-frameENST00000530055ENST00000357122NADSYN1chr11

71193071

+SPAG9chr17

49048217

-
In-frameENST00000530055ENST00000505279NADSYN1chr11

71193071

+SPAG9chr17

49048217

-
In-frameENST00000539574ENST00000262013NADSYN1chr11

71193071

+SPAG9chr17

49048217

-
In-frameENST00000539574ENST00000357122NADSYN1chr11

71193071

+SPAG9chr17

49048217

-
In-frameENST00000539574ENST00000505279NADSYN1chr11

71193071

+SPAG9chr17

49048217

-

check buttonORFfinder result based on the fusion transcript sequence of in-frame fusion genes.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandSeq length
(transcript)		BP loci
(transcript)		Predicted start
(transcript)		Predicted stop
(transcript)		Seq length
(amino acids)
ENST00000319023NADSYN1chr1171193071+ENST00000262013SPAG9chr1749048217-570213381881603471
ENST00000319023NADSYN1chr1171193071+ENST00000505279SPAG9chr1749048217-224913381881603471
ENST00000319023NADSYN1chr1171193071+ENST00000357122SPAG9chr1749048217-223213381881603471
ENST00000539574NADSYN1chr1171193071+ENST00000262013SPAG9chr1749048217-551611527821417211
ENST00000539574NADSYN1chr1171193071+ENST00000505279SPAG9chr1749048217-206311527821417211
ENST00000539574NADSYN1chr1171193071+ENST00000357122SPAG9chr1749048217-204611527821417211
ENST00000530055NADSYN1chr1171193071+ENST00000262013SPAG9chr1749048217-56221258127924265
ENST00000530055NADSYN1chr1171193071+ENST00000505279SPAG9chr1749048217-21691258127924265
ENST00000530055NADSYN1chr1171193071+ENST00000357122SPAG9chr1749048217-21521258127924265

check buttonDeepORF prediction of the coding potential based on the fusion transcript sequence of in-frame fusion genes. DeepORF is a coding potential classifier based on convolutional neural network by comparing the real Ribo-seq data. If the no-coding score < 0.5 and coding score > 0.5, then the in-frame fusion transcript is predicted as being likely translated.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandNo-coding scoreCoding score
ENST00000319023ENST00000262013NADSYN1chr1171193071+SPAG9chr1749048217-0.0001569360.999843
ENST00000319023ENST00000505279NADSYN1chr1171193071+SPAG9chr1749048217-0.0008154790.99918455
ENST00000319023ENST00000357122NADSYN1chr1171193071+SPAG9chr1749048217-0.0008219880.999178
ENST00000539574ENST00000262013NADSYN1chr1171193071+SPAG9chr1749048217-0.0013360470.9986639
ENST00000539574ENST00000505279NADSYN1chr1171193071+SPAG9chr1749048217-0.0045822870.9954177
ENST00000539574ENST00000357122NADSYN1chr1171193071+SPAG9chr1749048217-0.0046904870.99530953
ENST00000530055ENST00000262013NADSYN1chr1171193071+SPAG9chr1749048217-0.083411570.9165884
ENST00000530055ENST00000505279NADSYN1chr1171193071+SPAG9chr1749048217-0.12006550.8799345
ENST00000530055ENST00000357122NADSYN1chr1171193071+SPAG9chr1749048217-0.1238091140.8761909

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Fusion Genomic Features for NADSYN1-SPAG9


check buttonFusionAI prediction of the potential fusion gene breakpoint based on the pre-mature RNA sequence context (+/- 5kb of individual partner genes, total 20kb length sequence). FusionAI is a fusion gene breakpoint classifier based on convolutional neural network by comparing the fusion positive and negative sequence context of ~ 20K fusion gene data. From here, we can have the relative potentency of the 20K genomic sequence how individual sequnce will be likely used as the gene fusion breakpoints.
HgeneHchrHbpHstrandTgeneTchrTbpTstrand1-pp (fusion gene breakpoint)

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions. We integrated a total of 44 different types of human genomic feature loci information across five big categories including virus integration sites, repeats, structural variants, chromatin states, and gene expression regulation. More details are in help page.
genomic feature

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions that are ovelapped with the top 1% feature importance score regions. More details are in help page.

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Fusion Protein Features for NADSYN1-SPAG9


check button Four levels of functional features of fusion genes
Go to FGviewer search page for the most frequent breakpoint (https://ccsmweb.uth.edu/FGviewer/chr11:71193071/chr17:49048217)
- FGviewer provides the online visualization of the retention search of the protein functional features across DNA, RNA, protein, and pathological levels.
- How to search
1. Put your fusion gene symbol.
2. Press the tab key until there will be shown the breakpoint information filled.
4. Go down and press 'Search' tab twice.
4. Go down to have the hyperlink of the search result.
5. Click the hyperlink.
6. See the FGviewer result for your fusion gene.
FGviewer

check buttonMain function of each fusion partner protein. (from UniProt)
HgeneTgene
..
FUNCTION: Transcriptional activator which is required for calcium-dependent dendritic growth and branching in cortical neurons. Recruits CREB-binding protein (CREBBP) to nuclear bodies. Component of the CREST-BRG1 complex, a multiprotein complex that regulates promoter activation by orchestrating a calcium-dependent release of a repressor complex and a recruitment of an activator complex. In resting neurons, transcription of the c-FOS promoter is inhibited by BRG1-dependent recruitment of a phospho-RB1-HDAC1 repressor complex. Upon calcium influx, RB1 is dephosphorylated by calcineurin, which leads to release of the repressor complex. At the same time, there is increased recruitment of CREBBP to the promoter by a CREST-dependent mechanism, which leads to transcriptional activation. The CREST-BRG1 complex also binds to the NR2B promoter, and activity-dependent induction of NR2B expression involves a release of HDAC1 and recruitment of CREBBP (By similarity). {ECO:0000250}.FUNCTION: Transcriptional activator which is required for calcium-dependent dendritic growth and branching in cortical neurons. Recruits CREB-binding protein (CREBBP) to nuclear bodies. Component of the CREST-BRG1 complex, a multiprotein complex that regulates promoter activation by orchestrating a calcium-dependent release of a repressor complex and a recruitment of an activator complex. In resting neurons, transcription of the c-FOS promoter is inhibited by BRG1-dependent recruitment of a phospho-RB1-HDAC1 repressor complex. Upon calcium influx, RB1 is dephosphorylated by calcineurin, which leads to release of the repressor complex. At the same time, there is increased recruitment of CREBBP to the promoter by a CREST-dependent mechanism, which leads to transcriptional activation. The CREST-BRG1 complex also binds to the NR2B promoter, and activity-dependent induction of NR2B expression involves a release of HDAC1 and recruitment of CREBBP (By similarity). {ECO:0000250}.

check buttonRetention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at

download page


* Minus value of BPloci means that the break pointn is located before the CDS.
- In-frame and retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneNADSYN1chr11:71193071chr17:49048217ENST00000319023+13215_275383707.0DomainCN hydrolase
HgeneNADSYN1chr11:71193071chr17:49048217ENST00000319023+1321355_362383707.0Nucleotide bindingATP

- In-frame and not-retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneNADSYN1chr11:71193071chr17:49048217ENST00000319023+1321325_706383707.0RegionLigase
TgeneSPAG9chr11:71193071chr17:49048217ENST000002620132730408_53412331322.0Coiled coilOntology_term=ECO:0000269
TgeneSPAG9chr11:71193071chr17:49048217ENST00000262013273066_16612331322.0Coiled coilOntology_term=ECO:0000255
TgeneSPAG9chr11:71193071chr17:49048217ENST000002620132730724_75812331322.0Coiled coilOntology_term=ECO:0000255
TgeneSPAG9chr11:71193071chr17:49048217ENST000003571222629408_53412191308.0Coiled coilOntology_term=ECO:0000269
TgeneSPAG9chr11:71193071chr17:49048217ENST00000357122262966_16612191308.0Coiled coilOntology_term=ECO:0000255
TgeneSPAG9chr11:71193071chr17:49048217ENST000003571222629724_75812191308.0Coiled coilOntology_term=ECO:0000255
TgeneSPAG9chr11:71193071chr17:49048217ENST000005052792730408_53412231312.0Coiled coilOntology_term=ECO:0000269
TgeneSPAG9chr11:71193071chr17:49048217ENST00000505279273066_16612231312.0Coiled coilOntology_term=ECO:0000255
TgeneSPAG9chr11:71193071chr17:49048217ENST000005052792730724_75812231312.0Coiled coilOntology_term=ECO:0000255
TgeneSPAG9chr11:71193071chr17:49048217ENST000005102832427408_53410891178.0Coiled coilOntology_term=ECO:0000269
TgeneSPAG9chr11:71193071chr17:49048217ENST00000510283242766_16610891178.0Coiled coilOntology_term=ECO:0000255
TgeneSPAG9chr11:71193071chr17:49048217ENST000005102832427724_75810891178.0Coiled coilOntology_term=ECO:0000255
TgeneSPAG9chr11:71193071chr17:49048217ENST000002620132730500_57112331322.0DomainRH2
TgeneSPAG9chr11:71193071chr17:49048217ENST0000026201327307_9512331322.0DomainRH1
TgeneSPAG9chr11:71193071chr17:49048217ENST000003571222629500_57112191308.0DomainRH2
TgeneSPAG9chr11:71193071chr17:49048217ENST0000035712226297_9512191308.0DomainRH1
TgeneSPAG9chr11:71193071chr17:49048217ENST000005052792730500_57112231312.0DomainRH2
TgeneSPAG9chr11:71193071chr17:49048217ENST0000050527927307_9512231312.0DomainRH1
TgeneSPAG9chr11:71193071chr17:49048217ENST000005102832427500_57110891178.0DomainRH2
TgeneSPAG9chr11:71193071chr17:49048217ENST0000051028324277_9510891178.0DomainRH1


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Fusion Gene Sequence for NADSYN1-SPAG9


check button For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. To have fusion amino acid sequence, we ran ORFfinder and chose the longest ORF among the all predicted ones.
>57135_57135_1_NADSYN1-SPAG9_NADSYN1_chr11_71193071_ENST00000319023_SPAG9_chr17_49048217_ENST00000262013_length(transcript)=5702nt_BP=1338nt
AGACGGGGCGGGGCGATCCGTAGGCAGGGCCTGACGCCGCAGTCCTCCTTGGCCGGAGCCTCAACGGATGGGCGGGGAGGGGGCGGGGCC
GGGCAACCCGGAAGGTCCGGCGTCCCAGCCGCCTACCTCGCTGGGACCCTGGTCTTGCTGTCCCCCGCTGGCCTCCTGCCCAAGCGACTG
CGGCCAGGATGGGCCGGAAGGTGACCGTGGCCACCTGCGCACTCAACCAGTGGGCCCTGGACTTCGAGGGCAATTTGCAAAGAATTTTAA
AGAGTATTGAAATTGCCAAAAACAGAGGAGCAAGATACAGGCTTGGACCAGAGCTGGAAATATGCGGCTACGGATGTTGGGATCATTATT
ACGAGTCGGACACCCTCTTGCACTCGTTTCAAGTCCTAGCGGCCCTTGTGGAGTCTCCCGTCACTCAGGACATCATCTGCGACGTGGGGA
TGCCTGTAATGCACCGAAACGTCCGCTACAACTGCAGAGTGATATTCCTCAACAGGAAGATCCTGCTCATCAGACCCAAGATGGCCTTGG
CCAATGAAGGCAACTACCGCGAGCTGCGCTGGTTCACCCCGTGGTCGAGGAGTCGGCACACAGAGGAGTACTTTCTGCCTCGGATGATAC
AGGACCTGACAAAGCAGGAAACCGTACCCTTCGGAGATGCGGTGCTGGTGACATGGGACACCTGCATTGGAAGTGAGATCTGTGAGGAGC
TCTGGACACCCCACAGCCCGCACATCGACATGGGCCTGGATGGCGTGGAGATCATCACCAACGCCTCGGGCAGCCACCAAGTGCTGCGCA
AAGCCAACACCAGGGTGGATCTCGTGACTATGGTCACCAGCAAGAACGGTGGGATTTACTTGCTGGCCAACCAGAAGGGTTGTGACGGGG
ACCGCCTGTACTACGACGGCTGTGCCATGATTGCCATGAACGGAAGCGTCTTTGCTCAAGGATCCCAGTTTTCTCTGGATGACGTGGAAG
TCCTGACGGCCACGCTGGATCTGGAGGACGTCCGGAGCTACAGGGCGGAGATTTCATCTCGAAACCTGGCGGCCAGCAGGGCGAGCCCCT
ACCCCAGAGTGAAGGTGGACTTTGCCCTCTCGTGCCACGAGGACTTGCTGGCACCCATCTCTGAGCCCATCGAGTGGAAATACCACAGCC
CTGAGGAGGAGATAAGCCTTGGACCTGCCTGCTGGCTCTGGGATTTTTTAAGACGAAGTCAACAGGCAGGGTTTTTGCTGCCCTTGAGTG
GCGGGGTGGACAGCGCAGCCACCGCCTGCCTCATCTACTCCATGTGCTGCCAGGTCTGCGAGGCCGTGAGGAGTGGAAGTCAAGTCATCA
GCCCACAAAGTAGCAGTAGTGGCACGGATCTGACGGGTGACAAAGCAGGGCCATCTGCACAGGAGCCTGGTAGTCAGACGCCCTTGAAGT
CTATGCTTGTCATCAGTGGAGGAGAGGGCTACATCGACTTCCGAATGGGTGATGAAGGTGGAGAATCAGAACTTCTTGGAGAGGATCTTC
CACTTGAACCTTCTGTCACCAAAGCAGAAAGGAGTCACTTGATAGTGTGGCAAGTGATGTATGGCAATGAGTGAGCCCATGGGAAACAGG
TGGAGATGGGGAAGCCGTCTCTTCTGCATGGTTTATTTTCCCTCTATCCTTTTATTTAATGCTCTTTTGTGAGATAAGTTTCACCACATA
ATGTGTGAGCATTTTTTCCTGTTAACTTTATATTACAAAATCCGTTCTACCATAACAATACAGAGGAACTAGCTGTGTTACTGCACCAGT
GTTATAGGTAACTTCAGTATATTATGAACAAATCAAAGAATGTTTACTTCCTGCAAACTGGTGAATTATAGAAAGCAATCCAGATGTGGT
TTACTCTGCCACAGTCTAATGTCATTCACTTCATTTGATGGGGTCACTTGTTAGCTGTCACTAATAATGGAATTAATGGGAAACACTTGA
TAAATGAAACTGTACCGTTAAATACAATAGCTGAGTTTTCCCCAGTGTATTGTAAAATTGACACACACTAATACAAGATGGATTATCAGG
ATGTATCTAAATGTCCCGAGAGGGTTAAAAGCTAACTGTAAATTACTTTAACTTTCACTTTCAAATCTGACAAATCTTGTTTATATGGTA
TATAAAACTTTGTTTTCATCAGATTTGGGGGGGTTTTATATTAAAGAAATTAAGACTACACTATTTAAATAAACGTTTCCTGTTTCTGAC
TTATTAGAGCTCTAAAGTTTATGAGGCCTACTTCTCTGAATATTCTGATGGGTTTTTTTTGAGACCAGTCTCATTTTCATACTGACATGT
CTGAAAGATTTATTATTTATAAAGCTTAGGACATACTCTGGGAAGCTTAGAAGATACTTCAGCACTGGGAGGATTTTTTAAAGGAAATGT
GTTTTGTATTTCTTGTACCAGAGAATGGTGATGTTGATTGAGTTTTTTCCATGTAAAAAATGTACTTGTTTGCCAAATGTTCCTAGATTG
CTCTTAACCTGTTAATACAAGTAAAACTGTAGTGGGGATGGAGTCTGGCCTAAGTACAGAATGAGGGATTTAATTAGAAAAGTTATTTTC
TTTTGTTCTGTATCAAACTGCAGAACAGCTATATACTTGGTATTTTGTACGTGAATAACGTTTTAGCTTTTGTGCCCTTTTGAGCTTGAA
GGGTTATCCTCAAAGGGGAAAACTATGAAGGGGAAGAAGACAAACCTAAGATACCATAAAGTAAAGGTTGACATTACATATTTTCATTCA
CAATGCCCATTAAAAAAAAAAAATAGGTTGGGCATGGTGGCTCACGCCTGTAATCCCAACACTTTAGGAGGCTGAGGCAGATGGATTGCT
TGAGCCCAGGAGTTCAAGACCAGCCTGGGCAACATGGCGAAACCCTGTCTCTACCAAAAAAAAAAAACAAAATAAATTAACCGGGTGTGG
TGGCACATGCCTGTAGTCCCAGCTACTTGGGAGGCTGAGGTGGGAGGATGACCTGGGCCCAGGAGGTGGAGGTTGCAGTGAGCCTTGATA
GCACCACTGCACTCCAGCCTGGGTGACGGAGCAAGACCCTGTCTCAAAACAGACAAACAAGCAAAAAATAGATTAAAGTCTGGATTTCAC
TGATTTTCTTGCTTAATAAGTTTTTTAAAACCACGATGCTGCAATTTTTTCCCTCTCAAGCTTCTTGAAAATGTGTGATTTACCCTTTTT
TATCTATTACTCTAGGCAAAGCTAAATATGATTTTTTTTTTTTTTTTTGAGACGGAGTCTGGCTCTGTTGCCCAGGCTGGAATGCAGTGG
TGCGATCTCAGCTCACTGCAACCTCCACCTCTCAGGTTCAAGTAGTTCTCCTGCCTCAGCCTCCCAAGTAGCTGGGATTACAGGTGTGTG
CCACCCTGCCCAGCTAATTTTTGTATTTTTAGTAGAGACAGGGTTTCACCACATTGGCCAGGCTGGTCTCAAACTCCTGACCTCAGATGA
TCTACCCGCCTTGGCCTCCCGAAGTGCTTGAATTACAGGCGTGAGCCCCCGCGCCGGTCCGAAGCAAAGCTAAATGTAATTTTATGTACT
GTTTTAACAGTATAAACCTATGGGATAAAGGCCCCCAATCATCAGAAGGACTACTGAAAAGAAAAGAAAGCAAACGTAGATGTCAAATTG
TCTAAACATTCTTAAGTACCACTGATTTTTTTTTTCTGGACTATTATACAAAGATGTCTGTAAAAAGTATACCAGTGGCTTTTATGCATA
TACACGATTAGGCTAGATTGTGAAGTACATGGGATTTCATGAGCCAGAGGAGGCATTTGGATCCATTGGGCCACATGTGACTATAAGCAC
ATTGTGTACACAATAAAATTGTAGCCACTCATGTATTAAAACTGTTTTGGTAAAAGCTGTATTAAAAGAATAATTTTTTGCTTGAGCTAC
TTAGTCACTTTTTTGCAGGGCACCAAAATGTAGGCTACTTTTCCATAGCTTGTTTGCTATGTTTTTATTTCATCTTAAATCTGAGCCATT
TTTGGCAATATCTTTTAAAAAATCATTATTAAACATTTATTGGAAATGTTGTATAGATTCACAAGAAAGAGACACCAAAGTGTTTGGGAA
TTTTAATCCCAAGAAGTAAACATCCCAGAGTCAGATCCCATTTGCTGTTGTTCAGCCATGTTTGTATGACTGAATGTAATTTAGGAAATC
AGGAGTTAGAGATGAAAAATACAAACATGTCAAATGGTTGTAATTGCTTTTTTTGAACTTACTGGCTTTAACTTAAGTAATATAGGTGTG
TAGTTGTTTTATCTAAAGATGTCAGATTATCTGTGGCCCTGTTAATTAACTGCAGGGACCAGAGAGAGGACAAAAATGCCTGTATAATTT
GCTTTAAAGGCTTGTCCTTATGTTTGTAATTTCAGTTAAATATTTTCTACAGATTGCTTCACTTCCCCTTTCCCCCAATAACAAGTTCAT
ATTCTTGTAATGTTTACTTTGGTCAACGTGGTAATTTTTGGAAGAAAATGCCAAAATGTAAGCTTCTCACAAGCAGCAAAGGAATGTAAC
TGCCTGTAGCTACCACATCAAGGGAGAGAAGAGGCTTGCGTACTTTGGGTTGATCTCACTGTACAAAAAAAGTGTACCCCTATTGGAAGA
AATAAGGAATACTTGAAGGTTTCTCCTTTTTTTACACTTGAGTCATGTGCAAGGTTGAACCATATGAAATTGCCAGTGTTCAACCATTGC
TGATCTGCAAAAGCGACAATATCATATGCCTCAACCTAACACTTACTCTTAAATGCAGGTTAAAATCTCTGTGAGGCAAAGGGATAATAT
TCTCTAGGAACTCACTTTTGAGAGTATTTTTCTCTAACCCATGTGGATCTAAATTTTAAAAATAGGAATGAATCTCTTAATTGCAGCTTG
TGGAGAGTATAAAACATTTTGAGCACAATATGCAGCACATAACTTTTCAGATTGTGTTTGCATAGAAAAGGTTAAAATCAATTCTTTCAG
TTACTGTATTGTTCATTTCTTGTAAAGGTCTTCCTACATTTGAGACGAGACCCTTTAACATAGGCTGCCTTAGTAACAAAATAAAACAGA
TGTGTCATAATATTAACTGTCCTAAAGAACATGTGTCTTGCAAATGCCATGGAACTGAATATTTATTTCCTTGTGAGTATTATGACCGTT
ACCAAAGGACTCAACCAGATTTAGGGCTCTTCTTAATTGATCATGTTCAGAAAGGGACTCATTTGGTCCCACTTTGTAACATGGGAAGAG
TAGAAGAGAAAATTAAATGTGGAAATCATAAATGCTTTTCTAACAGGGTTATGCTATTCTGTAACACTAAATGTCTGTCTTTTCTCTTAA
AAGATTAAGTTTTATTAATTTTGTCATACATTTCTCTATTTGAATATATCTTAACCATTTTATGTTCCAAATTCGTTTTTTGTCCAAGAC
ATTCTATCAGAATTTTACTTGCCTCTATAATCTGAAAAATGGGTTCTAGAATGTCCCACTTGCTGTCTCTTAGAGGCTGAGCTTCATTTC
TATGAGCAAAGAGCTCATTTAGCAATGTAGTTATTTCAGTATTTATTTCTATTATGGAATCCCTGGGGTTCAGAATGTAACTTTGTACAT

>57135_57135_1_NADSYN1-SPAG9_NADSYN1_chr11_71193071_ENST00000319023_SPAG9_chr17_49048217_ENST00000262013_length(amino acids)=471AA_BP=384
MGRKVTVATCALNQWALDFEGNLQRILKSIEIAKNRGARYRLGPELEICGYGCWDHYYESDTLLHSFQVLAALVESPVTQDIICDVGMPV
MHRNVRYNCRVIFLNRKILLIRPKMALANEGNYRELRWFTPWSRSRHTEEYFLPRMIQDLTKQETVPFGDAVLVTWDTCIGSEICEELWT
PHSPHIDMGLDGVEIITNASGSHQVLRKANTRVDLVTMVTSKNGGIYLLANQKGCDGDRLYYDGCAMIAMNGSVFAQGSQFSLDDVEVLT
ATLDLEDVRSYRAEISSRNLAASRASPYPRVKVDFALSCHEDLLAPISEPIEWKYHSPEEEISLGPACWLWDFLRRSQQAGFLLPLSGGV
DSAATACLIYSMCCQVCEAVRSGSQVISPQSSSSGTDLTGDKAGPSAQEPGSQTPLKSMLVISGGEGYIDFRMGDEGGESELLGEDLPLE

--------------------------------------------------------------
>57135_57135_2_NADSYN1-SPAG9_NADSYN1_chr11_71193071_ENST00000319023_SPAG9_chr17_49048217_ENST00000357122_length(transcript)=2232nt_BP=1338nt
AGACGGGGCGGGGCGATCCGTAGGCAGGGCCTGACGCCGCAGTCCTCCTTGGCCGGAGCCTCAACGGATGGGCGGGGAGGGGGCGGGGCC
GGGCAACCCGGAAGGTCCGGCGTCCCAGCCGCCTACCTCGCTGGGACCCTGGTCTTGCTGTCCCCCGCTGGCCTCCTGCCCAAGCGACTG
CGGCCAGGATGGGCCGGAAGGTGACCGTGGCCACCTGCGCACTCAACCAGTGGGCCCTGGACTTCGAGGGCAATTTGCAAAGAATTTTAA
AGAGTATTGAAATTGCCAAAAACAGAGGAGCAAGATACAGGCTTGGACCAGAGCTGGAAATATGCGGCTACGGATGTTGGGATCATTATT
ACGAGTCGGACACCCTCTTGCACTCGTTTCAAGTCCTAGCGGCCCTTGTGGAGTCTCCCGTCACTCAGGACATCATCTGCGACGTGGGGA
TGCCTGTAATGCACCGAAACGTCCGCTACAACTGCAGAGTGATATTCCTCAACAGGAAGATCCTGCTCATCAGACCCAAGATGGCCTTGG
CCAATGAAGGCAACTACCGCGAGCTGCGCTGGTTCACCCCGTGGTCGAGGAGTCGGCACACAGAGGAGTACTTTCTGCCTCGGATGATAC
AGGACCTGACAAAGCAGGAAACCGTACCCTTCGGAGATGCGGTGCTGGTGACATGGGACACCTGCATTGGAAGTGAGATCTGTGAGGAGC
TCTGGACACCCCACAGCCCGCACATCGACATGGGCCTGGATGGCGTGGAGATCATCACCAACGCCTCGGGCAGCCACCAAGTGCTGCGCA
AAGCCAACACCAGGGTGGATCTCGTGACTATGGTCACCAGCAAGAACGGTGGGATTTACTTGCTGGCCAACCAGAAGGGTTGTGACGGGG
ACCGCCTGTACTACGACGGCTGTGCCATGATTGCCATGAACGGAAGCGTCTTTGCTCAAGGATCCCAGTTTTCTCTGGATGACGTGGAAG
TCCTGACGGCCACGCTGGATCTGGAGGACGTCCGGAGCTACAGGGCGGAGATTTCATCTCGAAACCTGGCGGCCAGCAGGGCGAGCCCCT
ACCCCAGAGTGAAGGTGGACTTTGCCCTCTCGTGCCACGAGGACTTGCTGGCACCCATCTCTGAGCCCATCGAGTGGAAATACCACAGCC
CTGAGGAGGAGATAAGCCTTGGACCTGCCTGCTGGCTCTGGGATTTTTTAAGACGAAGTCAACAGGCAGGGTTTTTGCTGCCCTTGAGTG
GCGGGGTGGACAGCGCAGCCACCGCCTGCCTCATCTACTCCATGTGCTGCCAGGTCTGCGAGGCCGTGAGGAGTGGAAGTCAAGTCATCA
GCCCACAAAGTAGCAGTAGTGGCACGGATCTGACGGGTGACAAAGCAGGGCCATCTGCACAGGAGCCTGGTAGTCAGACGCCCTTGAAGT
CTATGCTTGTCATCAGTGGAGGAGAGGGCTACATCGACTTCCGAATGGGTGATGAAGGTGGAGAATCAGAACTTCTTGGAGAGGATCTTC
CACTTGAACCTTCTGTCACCAAAGCAGAAAGGAGTCACTTGATAGTGTGGCAAGTGATGTATGGCAATGAGTGAGCCCATGGGAAACAGG
TGGAGATGGGGAAGCCGTCTCTTCTGCATGGTTTATTTTCCCTCTATCCTTTTATTTAATGCTCTTTTGTGAGATAAGTTTCACCACATA
ATGTGTGAGCATTTTTTCCTGTTAACTTTATATTACAAAATCCGTTCTACCATAACAATACAGAGGAACTAGCTGTGTTACTGCACCAGT
GTTATAGGTAACTTCAGTATATTATGAACAAATCAAAGAATGTTTACTTCCTGCAAACTGGTGAATTATAGAAAGCAATCCAGATGTGGT
TTACTCTGCCACAGTCTAATGTCATTCACTTCATTTGATGGGGTCACTTGTTAGCTGTCACTAATAATGGAATTAATGGGAAACACTTGA
TAAATGAAACTGTACCGTTAAATACAATAGCTGAGTTTTCCCCAGTGTATTGTAAAATTGACACACACTAATACAAGATGGATTATCAGG
ATGTATCTAAATGTCCCGAGAGGGTTAAAAGCTAACTGTAAATTACTTTAACTTTCACTTTCAAATCTGACAAATCTTGTTTATATGGTA

>57135_57135_2_NADSYN1-SPAG9_NADSYN1_chr11_71193071_ENST00000319023_SPAG9_chr17_49048217_ENST00000357122_length(amino acids)=471AA_BP=384
MGRKVTVATCALNQWALDFEGNLQRILKSIEIAKNRGARYRLGPELEICGYGCWDHYYESDTLLHSFQVLAALVESPVTQDIICDVGMPV
MHRNVRYNCRVIFLNRKILLIRPKMALANEGNYRELRWFTPWSRSRHTEEYFLPRMIQDLTKQETVPFGDAVLVTWDTCIGSEICEELWT
PHSPHIDMGLDGVEIITNASGSHQVLRKANTRVDLVTMVTSKNGGIYLLANQKGCDGDRLYYDGCAMIAMNGSVFAQGSQFSLDDVEVLT
ATLDLEDVRSYRAEISSRNLAASRASPYPRVKVDFALSCHEDLLAPISEPIEWKYHSPEEEISLGPACWLWDFLRRSQQAGFLLPLSGGV
DSAATACLIYSMCCQVCEAVRSGSQVISPQSSSSGTDLTGDKAGPSAQEPGSQTPLKSMLVISGGEGYIDFRMGDEGGESELLGEDLPLE

--------------------------------------------------------------
>57135_57135_3_NADSYN1-SPAG9_NADSYN1_chr11_71193071_ENST00000319023_SPAG9_chr17_49048217_ENST00000505279_length(transcript)=2249nt_BP=1338nt
AGACGGGGCGGGGCGATCCGTAGGCAGGGCCTGACGCCGCAGTCCTCCTTGGCCGGAGCCTCAACGGATGGGCGGGGAGGGGGCGGGGCC
GGGCAACCCGGAAGGTCCGGCGTCCCAGCCGCCTACCTCGCTGGGACCCTGGTCTTGCTGTCCCCCGCTGGCCTCCTGCCCAAGCGACTG
CGGCCAGGATGGGCCGGAAGGTGACCGTGGCCACCTGCGCACTCAACCAGTGGGCCCTGGACTTCGAGGGCAATTTGCAAAGAATTTTAA
AGAGTATTGAAATTGCCAAAAACAGAGGAGCAAGATACAGGCTTGGACCAGAGCTGGAAATATGCGGCTACGGATGTTGGGATCATTATT
ACGAGTCGGACACCCTCTTGCACTCGTTTCAAGTCCTAGCGGCCCTTGTGGAGTCTCCCGTCACTCAGGACATCATCTGCGACGTGGGGA
TGCCTGTAATGCACCGAAACGTCCGCTACAACTGCAGAGTGATATTCCTCAACAGGAAGATCCTGCTCATCAGACCCAAGATGGCCTTGG
CCAATGAAGGCAACTACCGCGAGCTGCGCTGGTTCACCCCGTGGTCGAGGAGTCGGCACACAGAGGAGTACTTTCTGCCTCGGATGATAC
AGGACCTGACAAAGCAGGAAACCGTACCCTTCGGAGATGCGGTGCTGGTGACATGGGACACCTGCATTGGAAGTGAGATCTGTGAGGAGC
TCTGGACACCCCACAGCCCGCACATCGACATGGGCCTGGATGGCGTGGAGATCATCACCAACGCCTCGGGCAGCCACCAAGTGCTGCGCA
AAGCCAACACCAGGGTGGATCTCGTGACTATGGTCACCAGCAAGAACGGTGGGATTTACTTGCTGGCCAACCAGAAGGGTTGTGACGGGG
ACCGCCTGTACTACGACGGCTGTGCCATGATTGCCATGAACGGAAGCGTCTTTGCTCAAGGATCCCAGTTTTCTCTGGATGACGTGGAAG
TCCTGACGGCCACGCTGGATCTGGAGGACGTCCGGAGCTACAGGGCGGAGATTTCATCTCGAAACCTGGCGGCCAGCAGGGCGAGCCCCT
ACCCCAGAGTGAAGGTGGACTTTGCCCTCTCGTGCCACGAGGACTTGCTGGCACCCATCTCTGAGCCCATCGAGTGGAAATACCACAGCC
CTGAGGAGGAGATAAGCCTTGGACCTGCCTGCTGGCTCTGGGATTTTTTAAGACGAAGTCAACAGGCAGGGTTTTTGCTGCCCTTGAGTG
GCGGGGTGGACAGCGCAGCCACCGCCTGCCTCATCTACTCCATGTGCTGCCAGGTCTGCGAGGCCGTGAGGAGTGGAAGTCAAGTCATCA
GCCCACAAAGTAGCAGTAGTGGCACGGATCTGACGGGTGACAAAGCAGGGCCATCTGCACAGGAGCCTGGTAGTCAGACGCCCTTGAAGT
CTATGCTTGTCATCAGTGGAGGAGAGGGCTACATCGACTTCCGAATGGGTGATGAAGGTGGAGAATCAGAACTTCTTGGAGAGGATCTTC
CACTTGAACCTTCTGTCACCAAAGCAGAAAGGAGTCACTTGATAGTGTGGCAAGTGATGTATGGCAATGAGTGAGCCCATGGGAAACAGG
TGGAGATGGGGAAGCCGTCTCTTCTGCATGGTTTATTTTCCCTCTATCCTTTTATTTAATGCTCTTTTGTGAGATAAGTTTCACCACATA
ATGTGTGAGCATTTTTTCCTGTTAACTTTATATTACAAAATCCGTTCTACCATAACAATACAGAGGAACTAGCTGTGTTACTGCACCAGT
GTTATAGGTAACTTCAGTATATTATGAACAAATCAAAGAATGTTTACTTCCTGCAAACTGGTGAATTATAGAAAGCAATCCAGATGTGGT
TTACTCTGCCACAGTCTAATGTCATTCACTTCATTTGATGGGGTCACTTGTTAGCTGTCACTAATAATGGAATTAATGGGAAACACTTGA
TAAATGAAACTGTACCGTTAAATACAATAGCTGAGTTTTCCCCAGTGTATTGTAAAATTGACACACACTAATACAAGATGGATTATCAGG
ATGTATCTAAATGTCCCGAGAGGGTTAAAAGCTAACTGTAAATTACTTTAACTTTCACTTTCAAATCTGACAAATCTTGTTTATATGGTA

>57135_57135_3_NADSYN1-SPAG9_NADSYN1_chr11_71193071_ENST00000319023_SPAG9_chr17_49048217_ENST00000505279_length(amino acids)=471AA_BP=384
MGRKVTVATCALNQWALDFEGNLQRILKSIEIAKNRGARYRLGPELEICGYGCWDHYYESDTLLHSFQVLAALVESPVTQDIICDVGMPV
MHRNVRYNCRVIFLNRKILLIRPKMALANEGNYRELRWFTPWSRSRHTEEYFLPRMIQDLTKQETVPFGDAVLVTWDTCIGSEICEELWT
PHSPHIDMGLDGVEIITNASGSHQVLRKANTRVDLVTMVTSKNGGIYLLANQKGCDGDRLYYDGCAMIAMNGSVFAQGSQFSLDDVEVLT
ATLDLEDVRSYRAEISSRNLAASRASPYPRVKVDFALSCHEDLLAPISEPIEWKYHSPEEEISLGPACWLWDFLRRSQQAGFLLPLSGGV
DSAATACLIYSMCCQVCEAVRSGSQVISPQSSSSGTDLTGDKAGPSAQEPGSQTPLKSMLVISGGEGYIDFRMGDEGGESELLGEDLPLE

--------------------------------------------------------------
>57135_57135_4_NADSYN1-SPAG9_NADSYN1_chr11_71193071_ENST00000530055_SPAG9_chr17_49048217_ENST00000262013_length(transcript)=5622nt_BP=1258nt
CTATGTTGCCTAGGATGGTCTTGAACTCCTGGGCTAAAGCAATCCTCTTGCCTCGGCCTCCCAAAGTGTTGGAATTACAGGCGTGAACTA
CCGTGCCCAGCCTTTTTTTCATAGCAGTTTTATTAAGTTGTATTTGCCATACCACCCAATGTATCCATTTAAGCACCTGATTCAGTGGTT
TTTCATGTACTCATGGAGTTATGCAGCCACAATCTTAGCGCATTTTCATTACCCCAAAAAGAAACTGTACCCATTATGCACCCCGTTCCC
CTCCTCCGGTCCTGGCAACCACAAGTCTACTGTCTGTCTTCATGGATTTGCCTATTCTCGACGTTTCATTGGGATGAAATCACACAGTGT
ATGGCTTCCACACTTTACTGTGCTGTTGTCAAGGTTTATCTATGTGTTGGGTGCAGCCACCCCTTGGTATCCACAGGGATTGGACCCAGG
AGCCTGCACCGATCCCCTGCAGGGATGCCTGTGTCCCACAGTGCCCCCTGCAAAACTCACTGATATGAAGAGTCGGCCCTCTGTATCCAT
GGGCTTCAGATCCTGTGATTACTGTATCTTCTGTCTGTGTGCAGTTGAATCTGCGGGTGTAGAACCCACAGACACAGGGAGTGGCTGTAG
CTTATCCCTTTGTATGGTCAGAGAGTGTTCCGTAGCGGGGATGGACACGTGTTCATTCACTCTTCCACTGATGGGCATCGGGAATGTTTC
CACTTTCTGTCTATCATTAACAATTCTGCTACAAACATACATGTACTTCTGTTGGAGGGGACACATGTTTTCATTTCTCTTGGGTGTGTC
TATCCAGGAGTGGAATTGGCTGGGTCTTATGGTAACTCTGTTAACTGTTTTTTGCTTTTTGGTTTTTTGTTTGTTTTTTGAGACGGAGTT
TCACCCTTGCTGTGAACTACCATAGGCTGGAGTACAATGGCGCAATCCCAGCTCAGCACAACCTCTGCCTCGTAGATTCAAGCCAGCAGG
GCGAGCCCCTACCCCAGAGTGAAGGTGGACTTTGCCCTCTCGTGCCACGAGGACTTGCTGGCACCCATCTCTGAGCCCATCGAGTGGAAA
TACCACAGCCCTGAGGAGGAGATAAGCCTTGGACCTGCCTGCTGGCTCTGGGATTTTTTAAGACGAAGTCAACAGGCAGGGTTTTTGCTG
CCCTTGAGTGGCGGGGTGGACAGCGCAGCCACCGCCTGCCTCATCTACTCCATGTGCTGCCAGGTCTGCGAGGCCGTGAGGAGTGGAAGT
CAAGTCATCAGCCCACAAAGTAGCAGTAGTGGCACGGATCTGACGGGTGACAAAGCAGGGCCATCTGCACAGGAGCCTGGTAGTCAGACG
CCCTTGAAGTCTATGCTTGTCATCAGTGGAGGAGAGGGCTACATCGACTTCCGAATGGGTGATGAAGGTGGAGAATCAGAACTTCTTGGA
GAGGATCTTCCACTTGAACCTTCTGTCACCAAAGCAGAAAGGAGTCACTTGATAGTGTGGCAAGTGATGTATGGCAATGAGTGAGCCCAT
GGGAAACAGGTGGAGATGGGGAAGCCGTCTCTTCTGCATGGTTTATTTTCCCTCTATCCTTTTATTTAATGCTCTTTTGTGAGATAAGTT
TCACCACATAATGTGTGAGCATTTTTTCCTGTTAACTTTATATTACAAAATCCGTTCTACCATAACAATACAGAGGAACTAGCTGTGTTA
CTGCACCAGTGTTATAGGTAACTTCAGTATATTATGAACAAATCAAAGAATGTTTACTTCCTGCAAACTGGTGAATTATAGAAAGCAATC
CAGATGTGGTTTACTCTGCCACAGTCTAATGTCATTCACTTCATTTGATGGGGTCACTTGTTAGCTGTCACTAATAATGGAATTAATGGG
AAACACTTGATAAATGAAACTGTACCGTTAAATACAATAGCTGAGTTTTCCCCAGTGTATTGTAAAATTGACACACACTAATACAAGATG
GATTATCAGGATGTATCTAAATGTCCCGAGAGGGTTAAAAGCTAACTGTAAATTACTTTAACTTTCACTTTCAAATCTGACAAATCTTGT
TTATATGGTATATAAAACTTTGTTTTCATCAGATTTGGGGGGGTTTTATATTAAAGAAATTAAGACTACACTATTTAAATAAACGTTTCC
TGTTTCTGACTTATTAGAGCTCTAAAGTTTATGAGGCCTACTTCTCTGAATATTCTGATGGGTTTTTTTTGAGACCAGTCTCATTTTCAT
ACTGACATGTCTGAAAGATTTATTATTTATAAAGCTTAGGACATACTCTGGGAAGCTTAGAAGATACTTCAGCACTGGGAGGATTTTTTA
AAGGAAATGTGTTTTGTATTTCTTGTACCAGAGAATGGTGATGTTGATTGAGTTTTTTCCATGTAAAAAATGTACTTGTTTGCCAAATGT
TCCTAGATTGCTCTTAACCTGTTAATACAAGTAAAACTGTAGTGGGGATGGAGTCTGGCCTAAGTACAGAATGAGGGATTTAATTAGAAA
AGTTATTTTCTTTTGTTCTGTATCAAACTGCAGAACAGCTATATACTTGGTATTTTGTACGTGAATAACGTTTTAGCTTTTGTGCCCTTT
TGAGCTTGAAGGGTTATCCTCAAAGGGGAAAACTATGAAGGGGAAGAAGACAAACCTAAGATACCATAAAGTAAAGGTTGACATTACATA
TTTTCATTCACAATGCCCATTAAAAAAAAAAAATAGGTTGGGCATGGTGGCTCACGCCTGTAATCCCAACACTTTAGGAGGCTGAGGCAG
ATGGATTGCTTGAGCCCAGGAGTTCAAGACCAGCCTGGGCAACATGGCGAAACCCTGTCTCTACCAAAAAAAAAAAACAAAATAAATTAA
CCGGGTGTGGTGGCACATGCCTGTAGTCCCAGCTACTTGGGAGGCTGAGGTGGGAGGATGACCTGGGCCCAGGAGGTGGAGGTTGCAGTG
AGCCTTGATAGCACCACTGCACTCCAGCCTGGGTGACGGAGCAAGACCCTGTCTCAAAACAGACAAACAAGCAAAAAATAGATTAAAGTC
TGGATTTCACTGATTTTCTTGCTTAATAAGTTTTTTAAAACCACGATGCTGCAATTTTTTCCCTCTCAAGCTTCTTGAAAATGTGTGATT
TACCCTTTTTTATCTATTACTCTAGGCAAAGCTAAATATGATTTTTTTTTTTTTTTTTGAGACGGAGTCTGGCTCTGTTGCCCAGGCTGG
AATGCAGTGGTGCGATCTCAGCTCACTGCAACCTCCACCTCTCAGGTTCAAGTAGTTCTCCTGCCTCAGCCTCCCAAGTAGCTGGGATTA
CAGGTGTGTGCCACCCTGCCCAGCTAATTTTTGTATTTTTAGTAGAGACAGGGTTTCACCACATTGGCCAGGCTGGTCTCAAACTCCTGA
CCTCAGATGATCTACCCGCCTTGGCCTCCCGAAGTGCTTGAATTACAGGCGTGAGCCCCCGCGCCGGTCCGAAGCAAAGCTAAATGTAAT
TTTATGTACTGTTTTAACAGTATAAACCTATGGGATAAAGGCCCCCAATCATCAGAAGGACTACTGAAAAGAAAAGAAAGCAAACGTAGA
TGTCAAATTGTCTAAACATTCTTAAGTACCACTGATTTTTTTTTTCTGGACTATTATACAAAGATGTCTGTAAAAAGTATACCAGTGGCT
TTTATGCATATACACGATTAGGCTAGATTGTGAAGTACATGGGATTTCATGAGCCAGAGGAGGCATTTGGATCCATTGGGCCACATGTGA
CTATAAGCACATTGTGTACACAATAAAATTGTAGCCACTCATGTATTAAAACTGTTTTGGTAAAAGCTGTATTAAAAGAATAATTTTTTG
CTTGAGCTACTTAGTCACTTTTTTGCAGGGCACCAAAATGTAGGCTACTTTTCCATAGCTTGTTTGCTATGTTTTTATTTCATCTTAAAT
CTGAGCCATTTTTGGCAATATCTTTTAAAAAATCATTATTAAACATTTATTGGAAATGTTGTATAGATTCACAAGAAAGAGACACCAAAG
TGTTTGGGAATTTTAATCCCAAGAAGTAAACATCCCAGAGTCAGATCCCATTTGCTGTTGTTCAGCCATGTTTGTATGACTGAATGTAAT
TTAGGAAATCAGGAGTTAGAGATGAAAAATACAAACATGTCAAATGGTTGTAATTGCTTTTTTTGAACTTACTGGCTTTAACTTAAGTAA
TATAGGTGTGTAGTTGTTTTATCTAAAGATGTCAGATTATCTGTGGCCCTGTTAATTAACTGCAGGGACCAGAGAGAGGACAAAAATGCC
TGTATAATTTGCTTTAAAGGCTTGTCCTTATGTTTGTAATTTCAGTTAAATATTTTCTACAGATTGCTTCACTTCCCCTTTCCCCCAATA
ACAAGTTCATATTCTTGTAATGTTTACTTTGGTCAACGTGGTAATTTTTGGAAGAAAATGCCAAAATGTAAGCTTCTCACAAGCAGCAAA
GGAATGTAACTGCCTGTAGCTACCACATCAAGGGAGAGAAGAGGCTTGCGTACTTTGGGTTGATCTCACTGTACAAAAAAAGTGTACCCC
TATTGGAAGAAATAAGGAATACTTGAAGGTTTCTCCTTTTTTTACACTTGAGTCATGTGCAAGGTTGAACCATATGAAATTGCCAGTGTT
CAACCATTGCTGATCTGCAAAAGCGACAATATCATATGCCTCAACCTAACACTTACTCTTAAATGCAGGTTAAAATCTCTGTGAGGCAAA
GGGATAATATTCTCTAGGAACTCACTTTTGAGAGTATTTTTCTCTAACCCATGTGGATCTAAATTTTAAAAATAGGAATGAATCTCTTAA
TTGCAGCTTGTGGAGAGTATAAAACATTTTGAGCACAATATGCAGCACATAACTTTTCAGATTGTGTTTGCATAGAAAAGGTTAAAATCA
ATTCTTTCAGTTACTGTATTGTTCATTTCTTGTAAAGGTCTTCCTACATTTGAGACGAGACCCTTTAACATAGGCTGCCTTAGTAACAAA
ATAAAACAGATGTGTCATAATATTAACTGTCCTAAAGAACATGTGTCTTGCAAATGCCATGGAACTGAATATTTATTTCCTTGTGAGTAT
TATGACCGTTACCAAAGGACTCAACCAGATTTAGGGCTCTTCTTAATTGATCATGTTCAGAAAGGGACTCATTTGGTCCCACTTTGTAAC
ATGGGAAGAGTAGAAGAGAAAATTAAATGTGGAAATCATAAATGCTTTTCTAACAGGGTTATGCTATTCTGTAACACTAAATGTCTGTCT
TTTCTCTTAAAAGATTAAGTTTTATTAATTTTGTCATACATTTCTCTATTTGAATATATCTTAACCATTTTATGTTCCAAATTCGTTTTT
TGTCCAAGACATTCTATCAGAATTTTACTTGCCTCTATAATCTGAAAAATGGGTTCTAGAATGTCCCACTTGCTGTCTCTTAGAGGCTGA
GCTTCATTTCTATGAGCAAAGAGCTCATTTAGCAATGTAGTTATTTCAGTATTTATTTCTATTATGGAATCCCTGGGGTTCAGAATGTAA

>57135_57135_4_NADSYN1-SPAG9_NADSYN1_chr11_71193071_ENST00000530055_SPAG9_chr17_49048217_ENST00000262013_length(amino acids)=265AA_BP=
MYLPYHPMYPFKHLIQWFFMYSWSYAATILAHFHYPKKKLYPLCTPFPSSGPGNHKSTVCLHGFAYSRRFIGMKSHSVWLPHFTVLLSRF
IYVLGAATPWYPQGLDPGACTDPLQGCLCPTVPPAKLTDMKSRPSVSMGFRSCDYCIFCLCAVESAGVEPTDTGSGCSLSLCMVRECSVA

--------------------------------------------------------------
>57135_57135_5_NADSYN1-SPAG9_NADSYN1_chr11_71193071_ENST00000530055_SPAG9_chr17_49048217_ENST00000357122_length(transcript)=2152nt_BP=1258nt
CTATGTTGCCTAGGATGGTCTTGAACTCCTGGGCTAAAGCAATCCTCTTGCCTCGGCCTCCCAAAGTGTTGGAATTACAGGCGTGAACTA
CCGTGCCCAGCCTTTTTTTCATAGCAGTTTTATTAAGTTGTATTTGCCATACCACCCAATGTATCCATTTAAGCACCTGATTCAGTGGTT
TTTCATGTACTCATGGAGTTATGCAGCCACAATCTTAGCGCATTTTCATTACCCCAAAAAGAAACTGTACCCATTATGCACCCCGTTCCC
CTCCTCCGGTCCTGGCAACCACAAGTCTACTGTCTGTCTTCATGGATTTGCCTATTCTCGACGTTTCATTGGGATGAAATCACACAGTGT
ATGGCTTCCACACTTTACTGTGCTGTTGTCAAGGTTTATCTATGTGTTGGGTGCAGCCACCCCTTGGTATCCACAGGGATTGGACCCAGG
AGCCTGCACCGATCCCCTGCAGGGATGCCTGTGTCCCACAGTGCCCCCTGCAAAACTCACTGATATGAAGAGTCGGCCCTCTGTATCCAT
GGGCTTCAGATCCTGTGATTACTGTATCTTCTGTCTGTGTGCAGTTGAATCTGCGGGTGTAGAACCCACAGACACAGGGAGTGGCTGTAG
CTTATCCCTTTGTATGGTCAGAGAGTGTTCCGTAGCGGGGATGGACACGTGTTCATTCACTCTTCCACTGATGGGCATCGGGAATGTTTC
CACTTTCTGTCTATCATTAACAATTCTGCTACAAACATACATGTACTTCTGTTGGAGGGGACACATGTTTTCATTTCTCTTGGGTGTGTC
TATCCAGGAGTGGAATTGGCTGGGTCTTATGGTAACTCTGTTAACTGTTTTTTGCTTTTTGGTTTTTTGTTTGTTTTTTGAGACGGAGTT
TCACCCTTGCTGTGAACTACCATAGGCTGGAGTACAATGGCGCAATCCCAGCTCAGCACAACCTCTGCCTCGTAGATTCAAGCCAGCAGG
GCGAGCCCCTACCCCAGAGTGAAGGTGGACTTTGCCCTCTCGTGCCACGAGGACTTGCTGGCACCCATCTCTGAGCCCATCGAGTGGAAA
TACCACAGCCCTGAGGAGGAGATAAGCCTTGGACCTGCCTGCTGGCTCTGGGATTTTTTAAGACGAAGTCAACAGGCAGGGTTTTTGCTG
CCCTTGAGTGGCGGGGTGGACAGCGCAGCCACCGCCTGCCTCATCTACTCCATGTGCTGCCAGGTCTGCGAGGCCGTGAGGAGTGGAAGT
CAAGTCATCAGCCCACAAAGTAGCAGTAGTGGCACGGATCTGACGGGTGACAAAGCAGGGCCATCTGCACAGGAGCCTGGTAGTCAGACG
CCCTTGAAGTCTATGCTTGTCATCAGTGGAGGAGAGGGCTACATCGACTTCCGAATGGGTGATGAAGGTGGAGAATCAGAACTTCTTGGA
GAGGATCTTCCACTTGAACCTTCTGTCACCAAAGCAGAAAGGAGTCACTTGATAGTGTGGCAAGTGATGTATGGCAATGAGTGAGCCCAT
GGGAAACAGGTGGAGATGGGGAAGCCGTCTCTTCTGCATGGTTTATTTTCCCTCTATCCTTTTATTTAATGCTCTTTTGTGAGATAAGTT
TCACCACATAATGTGTGAGCATTTTTTCCTGTTAACTTTATATTACAAAATCCGTTCTACCATAACAATACAGAGGAACTAGCTGTGTTA
CTGCACCAGTGTTATAGGTAACTTCAGTATATTATGAACAAATCAAAGAATGTTTACTTCCTGCAAACTGGTGAATTATAGAAAGCAATC
CAGATGTGGTTTACTCTGCCACAGTCTAATGTCATTCACTTCATTTGATGGGGTCACTTGTTAGCTGTCACTAATAATGGAATTAATGGG
AAACACTTGATAAATGAAACTGTACCGTTAAATACAATAGCTGAGTTTTCCCCAGTGTATTGTAAAATTGACACACACTAATACAAGATG
GATTATCAGGATGTATCTAAATGTCCCGAGAGGGTTAAAAGCTAACTGTAAATTACTTTAACTTTCACTTTCAAATCTGACAAATCTTGT

>57135_57135_5_NADSYN1-SPAG9_NADSYN1_chr11_71193071_ENST00000530055_SPAG9_chr17_49048217_ENST00000357122_length(amino acids)=265AA_BP=
MYLPYHPMYPFKHLIQWFFMYSWSYAATILAHFHYPKKKLYPLCTPFPSSGPGNHKSTVCLHGFAYSRRFIGMKSHSVWLPHFTVLLSRF
IYVLGAATPWYPQGLDPGACTDPLQGCLCPTVPPAKLTDMKSRPSVSMGFRSCDYCIFCLCAVESAGVEPTDTGSGCSLSLCMVRECSVA

--------------------------------------------------------------
>57135_57135_6_NADSYN1-SPAG9_NADSYN1_chr11_71193071_ENST00000530055_SPAG9_chr17_49048217_ENST00000505279_length(transcript)=2169nt_BP=1258nt
CTATGTTGCCTAGGATGGTCTTGAACTCCTGGGCTAAAGCAATCCTCTTGCCTCGGCCTCCCAAAGTGTTGGAATTACAGGCGTGAACTA
CCGTGCCCAGCCTTTTTTTCATAGCAGTTTTATTAAGTTGTATTTGCCATACCACCCAATGTATCCATTTAAGCACCTGATTCAGTGGTT
TTTCATGTACTCATGGAGTTATGCAGCCACAATCTTAGCGCATTTTCATTACCCCAAAAAGAAACTGTACCCATTATGCACCCCGTTCCC
CTCCTCCGGTCCTGGCAACCACAAGTCTACTGTCTGTCTTCATGGATTTGCCTATTCTCGACGTTTCATTGGGATGAAATCACACAGTGT
ATGGCTTCCACACTTTACTGTGCTGTTGTCAAGGTTTATCTATGTGTTGGGTGCAGCCACCCCTTGGTATCCACAGGGATTGGACCCAGG
AGCCTGCACCGATCCCCTGCAGGGATGCCTGTGTCCCACAGTGCCCCCTGCAAAACTCACTGATATGAAGAGTCGGCCCTCTGTATCCAT
GGGCTTCAGATCCTGTGATTACTGTATCTTCTGTCTGTGTGCAGTTGAATCTGCGGGTGTAGAACCCACAGACACAGGGAGTGGCTGTAG
CTTATCCCTTTGTATGGTCAGAGAGTGTTCCGTAGCGGGGATGGACACGTGTTCATTCACTCTTCCACTGATGGGCATCGGGAATGTTTC
CACTTTCTGTCTATCATTAACAATTCTGCTACAAACATACATGTACTTCTGTTGGAGGGGACACATGTTTTCATTTCTCTTGGGTGTGTC
TATCCAGGAGTGGAATTGGCTGGGTCTTATGGTAACTCTGTTAACTGTTTTTTGCTTTTTGGTTTTTTGTTTGTTTTTTGAGACGGAGTT
TCACCCTTGCTGTGAACTACCATAGGCTGGAGTACAATGGCGCAATCCCAGCTCAGCACAACCTCTGCCTCGTAGATTCAAGCCAGCAGG
GCGAGCCCCTACCCCAGAGTGAAGGTGGACTTTGCCCTCTCGTGCCACGAGGACTTGCTGGCACCCATCTCTGAGCCCATCGAGTGGAAA
TACCACAGCCCTGAGGAGGAGATAAGCCTTGGACCTGCCTGCTGGCTCTGGGATTTTTTAAGACGAAGTCAACAGGCAGGGTTTTTGCTG
CCCTTGAGTGGCGGGGTGGACAGCGCAGCCACCGCCTGCCTCATCTACTCCATGTGCTGCCAGGTCTGCGAGGCCGTGAGGAGTGGAAGT
CAAGTCATCAGCCCACAAAGTAGCAGTAGTGGCACGGATCTGACGGGTGACAAAGCAGGGCCATCTGCACAGGAGCCTGGTAGTCAGACG
CCCTTGAAGTCTATGCTTGTCATCAGTGGAGGAGAGGGCTACATCGACTTCCGAATGGGTGATGAAGGTGGAGAATCAGAACTTCTTGGA
GAGGATCTTCCACTTGAACCTTCTGTCACCAAAGCAGAAAGGAGTCACTTGATAGTGTGGCAAGTGATGTATGGCAATGAGTGAGCCCAT
GGGAAACAGGTGGAGATGGGGAAGCCGTCTCTTCTGCATGGTTTATTTTCCCTCTATCCTTTTATTTAATGCTCTTTTGTGAGATAAGTT
TCACCACATAATGTGTGAGCATTTTTTCCTGTTAACTTTATATTACAAAATCCGTTCTACCATAACAATACAGAGGAACTAGCTGTGTTA
CTGCACCAGTGTTATAGGTAACTTCAGTATATTATGAACAAATCAAAGAATGTTTACTTCCTGCAAACTGGTGAATTATAGAAAGCAATC
CAGATGTGGTTTACTCTGCCACAGTCTAATGTCATTCACTTCATTTGATGGGGTCACTTGTTAGCTGTCACTAATAATGGAATTAATGGG
AAACACTTGATAAATGAAACTGTACCGTTAAATACAATAGCTGAGTTTTCCCCAGTGTATTGTAAAATTGACACACACTAATACAAGATG
GATTATCAGGATGTATCTAAATGTCCCGAGAGGGTTAAAAGCTAACTGTAAATTACTTTAACTTTCACTTTCAAATCTGACAAATCTTGT
TTATATGGTATATAAAACTTTGTTTTCATCAGATTTGGGGGGGTTTTATATTAAAGAAATTAAGACTACACTATTTAAATAAACGTTTCC

>57135_57135_6_NADSYN1-SPAG9_NADSYN1_chr11_71193071_ENST00000530055_SPAG9_chr17_49048217_ENST00000505279_length(amino acids)=265AA_BP=
MYLPYHPMYPFKHLIQWFFMYSWSYAATILAHFHYPKKKLYPLCTPFPSSGPGNHKSTVCLHGFAYSRRFIGMKSHSVWLPHFTVLLSRF
IYVLGAATPWYPQGLDPGACTDPLQGCLCPTVPPAKLTDMKSRPSVSMGFRSCDYCIFCLCAVESAGVEPTDTGSGCSLSLCMVRECSVA

--------------------------------------------------------------
>57135_57135_7_NADSYN1-SPAG9_NADSYN1_chr11_71193071_ENST00000539574_SPAG9_chr17_49048217_ENST00000262013_length(transcript)=5516nt_BP=1152nt
ATCATTAACCGCGACAGAGCTGGAAGGGCTTTGAAGAGAAGGATTAAGTTCCTGCTGATGGGAAGTGTGGTCCTCTCCCCGTTCACGTCA
GAGCCACAGGCACATTGGTGGTCGTGTTGATTGGCAGGTGTGTTGGCAATCAATCACCTGCCCCAGGACCCCCGCAGGTTCCCGGCCCCA
CATCAAGCCACCAAATCGGAGTCCTCGGGGGTCTGTATATTTAGTGAGCACCAGGCAGTTGTTTCGTGCATTAGAATCCGGGAGCCGTTG
CCTTACACGTCTCTAGAGTTCCTGATGTTGCCTGAGAGCTCCGTCGTAGGCTGTGGCCACAGGCCTGCTGTATTCAGAGTGGCCGCGCTG
TCCTCAGGCTCGGGCCACTGCCCTCCACCAGGTCCTCCGTGGTGCACCTGAAATGGTCAACAGAAGTCTTGTGACACGTGGAATCATTTC
AGAGTCACCCCTTCTGCCTCCTGCTCAAGCAACAGACCTGCCGATCACCCCCGTCGGGCCCGCGTTTCTCAGGGTCTTCCTAATCCCCTG
GGCTTTCCGGCTTGTCGTGTGCCTGGAGTCAGGCCGCCGTGCGGCAGGCTGTTAACCTAGCCTCGGGGAGAGTGGGATGGAGCCACCTTC
TCATGGAACGATCCTCGCCTTCCCTCATCTCCATTGTTTTATGGCTTCACACGGACCGTGGCTTTCTGCATGGAAGCTTGGTGGCCAGGG
TGCTGTCACTTTGGGAAGCAGCCAGAGAACCACAGGATGCGTGAATCGGTCTCCTTGTCTTCATGGGCATCTCCGGCCAGGAAGTCCTGA
CGGCCACGCTGGATCTGGAGGACGTCCGGAGCTACAGGGCGGAGATTTCATCTCGAAACCTGGCGGCCAGCAGGGCGAGCCCCTACCCCA
GAGTGAAGGTGGACTTTGCCCTCTCGTGCCACGAGGACTTGCTGGCACCCATCTCTGAGCCCATCGAGTGGAAATACCACAGCCCTGAGG
AGGAGATAAGCCTTGGACCTGCCTGCTGGCTCTGGGATTTTTTAAGACGAAGTCAACAGGCAGGGTTTTTGCTGCCCTTGAGTGGCGGGG
TGGACAGCGCAGCCACCGCCTGCCTCATCTACTCCATGTGCTGCCAGGTCTGCGAGGCCGTGAGGAGTGGAAGTCAAGTCATCAGCCCAC
AAAGTAGCAGTAGTGGCACGGATCTGACGGGTGACAAAGCAGGGCCATCTGCACAGGAGCCTGGTAGTCAGACGCCCTTGAAGTCTATGC
TTGTCATCAGTGGAGGAGAGGGCTACATCGACTTCCGAATGGGTGATGAAGGTGGAGAATCAGAACTTCTTGGAGAGGATCTTCCACTTG
AACCTTCTGTCACCAAAGCAGAAAGGAGTCACTTGATAGTGTGGCAAGTGATGTATGGCAATGAGTGAGCCCATGGGAAACAGGTGGAGA
TGGGGAAGCCGTCTCTTCTGCATGGTTTATTTTCCCTCTATCCTTTTATTTAATGCTCTTTTGTGAGATAAGTTTCACCACATAATGTGT
GAGCATTTTTTCCTGTTAACTTTATATTACAAAATCCGTTCTACCATAACAATACAGAGGAACTAGCTGTGTTACTGCACCAGTGTTATA
GGTAACTTCAGTATATTATGAACAAATCAAAGAATGTTTACTTCCTGCAAACTGGTGAATTATAGAAAGCAATCCAGATGTGGTTTACTC
TGCCACAGTCTAATGTCATTCACTTCATTTGATGGGGTCACTTGTTAGCTGTCACTAATAATGGAATTAATGGGAAACACTTGATAAATG
AAACTGTACCGTTAAATACAATAGCTGAGTTTTCCCCAGTGTATTGTAAAATTGACACACACTAATACAAGATGGATTATCAGGATGTAT
CTAAATGTCCCGAGAGGGTTAAAAGCTAACTGTAAATTACTTTAACTTTCACTTTCAAATCTGACAAATCTTGTTTATATGGTATATAAA
ACTTTGTTTTCATCAGATTTGGGGGGGTTTTATATTAAAGAAATTAAGACTACACTATTTAAATAAACGTTTCCTGTTTCTGACTTATTA
GAGCTCTAAAGTTTATGAGGCCTACTTCTCTGAATATTCTGATGGGTTTTTTTTGAGACCAGTCTCATTTTCATACTGACATGTCTGAAA
GATTTATTATTTATAAAGCTTAGGACATACTCTGGGAAGCTTAGAAGATACTTCAGCACTGGGAGGATTTTTTAAAGGAAATGTGTTTTG
TATTTCTTGTACCAGAGAATGGTGATGTTGATTGAGTTTTTTCCATGTAAAAAATGTACTTGTTTGCCAAATGTTCCTAGATTGCTCTTA
ACCTGTTAATACAAGTAAAACTGTAGTGGGGATGGAGTCTGGCCTAAGTACAGAATGAGGGATTTAATTAGAAAAGTTATTTTCTTTTGT
TCTGTATCAAACTGCAGAACAGCTATATACTTGGTATTTTGTACGTGAATAACGTTTTAGCTTTTGTGCCCTTTTGAGCTTGAAGGGTTA
TCCTCAAAGGGGAAAACTATGAAGGGGAAGAAGACAAACCTAAGATACCATAAAGTAAAGGTTGACATTACATATTTTCATTCACAATGC
CCATTAAAAAAAAAAAATAGGTTGGGCATGGTGGCTCACGCCTGTAATCCCAACACTTTAGGAGGCTGAGGCAGATGGATTGCTTGAGCC
CAGGAGTTCAAGACCAGCCTGGGCAACATGGCGAAACCCTGTCTCTACCAAAAAAAAAAAACAAAATAAATTAACCGGGTGTGGTGGCAC
ATGCCTGTAGTCCCAGCTACTTGGGAGGCTGAGGTGGGAGGATGACCTGGGCCCAGGAGGTGGAGGTTGCAGTGAGCCTTGATAGCACCA
CTGCACTCCAGCCTGGGTGACGGAGCAAGACCCTGTCTCAAAACAGACAAACAAGCAAAAAATAGATTAAAGTCTGGATTTCACTGATTT
TCTTGCTTAATAAGTTTTTTAAAACCACGATGCTGCAATTTTTTCCCTCTCAAGCTTCTTGAAAATGTGTGATTTACCCTTTTTTATCTA
TTACTCTAGGCAAAGCTAAATATGATTTTTTTTTTTTTTTTTGAGACGGAGTCTGGCTCTGTTGCCCAGGCTGGAATGCAGTGGTGCGAT
CTCAGCTCACTGCAACCTCCACCTCTCAGGTTCAAGTAGTTCTCCTGCCTCAGCCTCCCAAGTAGCTGGGATTACAGGTGTGTGCCACCC
TGCCCAGCTAATTTTTGTATTTTTAGTAGAGACAGGGTTTCACCACATTGGCCAGGCTGGTCTCAAACTCCTGACCTCAGATGATCTACC
CGCCTTGGCCTCCCGAAGTGCTTGAATTACAGGCGTGAGCCCCCGCGCCGGTCCGAAGCAAAGCTAAATGTAATTTTATGTACTGTTTTA
ACAGTATAAACCTATGGGATAAAGGCCCCCAATCATCAGAAGGACTACTGAAAAGAAAAGAAAGCAAACGTAGATGTCAAATTGTCTAAA
CATTCTTAAGTACCACTGATTTTTTTTTTCTGGACTATTATACAAAGATGTCTGTAAAAAGTATACCAGTGGCTTTTATGCATATACACG
ATTAGGCTAGATTGTGAAGTACATGGGATTTCATGAGCCAGAGGAGGCATTTGGATCCATTGGGCCACATGTGACTATAAGCACATTGTG
TACACAATAAAATTGTAGCCACTCATGTATTAAAACTGTTTTGGTAAAAGCTGTATTAAAAGAATAATTTTTTGCTTGAGCTACTTAGTC
ACTTTTTTGCAGGGCACCAAAATGTAGGCTACTTTTCCATAGCTTGTTTGCTATGTTTTTATTTCATCTTAAATCTGAGCCATTTTTGGC
AATATCTTTTAAAAAATCATTATTAAACATTTATTGGAAATGTTGTATAGATTCACAAGAAAGAGACACCAAAGTGTTTGGGAATTTTAA
TCCCAAGAAGTAAACATCCCAGAGTCAGATCCCATTTGCTGTTGTTCAGCCATGTTTGTATGACTGAATGTAATTTAGGAAATCAGGAGT
TAGAGATGAAAAATACAAACATGTCAAATGGTTGTAATTGCTTTTTTTGAACTTACTGGCTTTAACTTAAGTAATATAGGTGTGTAGTTG
TTTTATCTAAAGATGTCAGATTATCTGTGGCCCTGTTAATTAACTGCAGGGACCAGAGAGAGGACAAAAATGCCTGTATAATTTGCTTTA
AAGGCTTGTCCTTATGTTTGTAATTTCAGTTAAATATTTTCTACAGATTGCTTCACTTCCCCTTTCCCCCAATAACAAGTTCATATTCTT
GTAATGTTTACTTTGGTCAACGTGGTAATTTTTGGAAGAAAATGCCAAAATGTAAGCTTCTCACAAGCAGCAAAGGAATGTAACTGCCTG
TAGCTACCACATCAAGGGAGAGAAGAGGCTTGCGTACTTTGGGTTGATCTCACTGTACAAAAAAAGTGTACCCCTATTGGAAGAAATAAG
GAATACTTGAAGGTTTCTCCTTTTTTTACACTTGAGTCATGTGCAAGGTTGAACCATATGAAATTGCCAGTGTTCAACCATTGCTGATCT
GCAAAAGCGACAATATCATATGCCTCAACCTAACACTTACTCTTAAATGCAGGTTAAAATCTCTGTGAGGCAAAGGGATAATATTCTCTA
GGAACTCACTTTTGAGAGTATTTTTCTCTAACCCATGTGGATCTAAATTTTAAAAATAGGAATGAATCTCTTAATTGCAGCTTGTGGAGA
GTATAAAACATTTTGAGCACAATATGCAGCACATAACTTTTCAGATTGTGTTTGCATAGAAAAGGTTAAAATCAATTCTTTCAGTTACTG
TATTGTTCATTTCTTGTAAAGGTCTTCCTACATTTGAGACGAGACCCTTTAACATAGGCTGCCTTAGTAACAAAATAAAACAGATGTGTC
ATAATATTAACTGTCCTAAAGAACATGTGTCTTGCAAATGCCATGGAACTGAATATTTATTTCCTTGTGAGTATTATGACCGTTACCAAA
GGACTCAACCAGATTTAGGGCTCTTCTTAATTGATCATGTTCAGAAAGGGACTCATTTGGTCCCACTTTGTAACATGGGAAGAGTAGAAG
AGAAAATTAAATGTGGAAATCATAAATGCTTTTCTAACAGGGTTATGCTATTCTGTAACACTAAATGTCTGTCTTTTCTCTTAAAAGATT
AAGTTTTATTAATTTTGTCATACATTTCTCTATTTGAATATATCTTAACCATTTTATGTTCCAAATTCGTTTTTTGTCCAAGACATTCTA
TCAGAATTTTACTTGCCTCTATAATCTGAAAAATGGGTTCTAGAATGTCCCACTTGCTGTCTCTTAGAGGCTGAGCTTCATTTCTATGAG
CAAAGAGCTCATTTAGCAATGTAGTTATTTCAGTATTTATTTCTATTATGGAATCCCTGGGGTTCAGAATGTAACTTTGTACATGAGATA

>57135_57135_7_NADSYN1-SPAG9_NADSYN1_chr11_71193071_ENST00000539574_SPAG9_chr17_49048217_ENST00000262013_length(amino acids)=211AA_BP=124
MGISGQEVLTATLDLEDVRSYRAEISSRNLAASRASPYPRVKVDFALSCHEDLLAPISEPIEWKYHSPEEEISLGPACWLWDFLRRSQQA
GFLLPLSGGVDSAATACLIYSMCCQVCEAVRSGSQVISPQSSSSGTDLTGDKAGPSAQEPGSQTPLKSMLVISGGEGYIDFRMGDEGGES

--------------------------------------------------------------
>57135_57135_8_NADSYN1-SPAG9_NADSYN1_chr11_71193071_ENST00000539574_SPAG9_chr17_49048217_ENST00000357122_length(transcript)=2046nt_BP=1152nt
ATCATTAACCGCGACAGAGCTGGAAGGGCTTTGAAGAGAAGGATTAAGTTCCTGCTGATGGGAAGTGTGGTCCTCTCCCCGTTCACGTCA
GAGCCACAGGCACATTGGTGGTCGTGTTGATTGGCAGGTGTGTTGGCAATCAATCACCTGCCCCAGGACCCCCGCAGGTTCCCGGCCCCA
CATCAAGCCACCAAATCGGAGTCCTCGGGGGTCTGTATATTTAGTGAGCACCAGGCAGTTGTTTCGTGCATTAGAATCCGGGAGCCGTTG
CCTTACACGTCTCTAGAGTTCCTGATGTTGCCTGAGAGCTCCGTCGTAGGCTGTGGCCACAGGCCTGCTGTATTCAGAGTGGCCGCGCTG
TCCTCAGGCTCGGGCCACTGCCCTCCACCAGGTCCTCCGTGGTGCACCTGAAATGGTCAACAGAAGTCTTGTGACACGTGGAATCATTTC
AGAGTCACCCCTTCTGCCTCCTGCTCAAGCAACAGACCTGCCGATCACCCCCGTCGGGCCCGCGTTTCTCAGGGTCTTCCTAATCCCCTG
GGCTTTCCGGCTTGTCGTGTGCCTGGAGTCAGGCCGCCGTGCGGCAGGCTGTTAACCTAGCCTCGGGGAGAGTGGGATGGAGCCACCTTC
TCATGGAACGATCCTCGCCTTCCCTCATCTCCATTGTTTTATGGCTTCACACGGACCGTGGCTTTCTGCATGGAAGCTTGGTGGCCAGGG
TGCTGTCACTTTGGGAAGCAGCCAGAGAACCACAGGATGCGTGAATCGGTCTCCTTGTCTTCATGGGCATCTCCGGCCAGGAAGTCCTGA
CGGCCACGCTGGATCTGGAGGACGTCCGGAGCTACAGGGCGGAGATTTCATCTCGAAACCTGGCGGCCAGCAGGGCGAGCCCCTACCCCA
GAGTGAAGGTGGACTTTGCCCTCTCGTGCCACGAGGACTTGCTGGCACCCATCTCTGAGCCCATCGAGTGGAAATACCACAGCCCTGAGG
AGGAGATAAGCCTTGGACCTGCCTGCTGGCTCTGGGATTTTTTAAGACGAAGTCAACAGGCAGGGTTTTTGCTGCCCTTGAGTGGCGGGG
TGGACAGCGCAGCCACCGCCTGCCTCATCTACTCCATGTGCTGCCAGGTCTGCGAGGCCGTGAGGAGTGGAAGTCAAGTCATCAGCCCAC
AAAGTAGCAGTAGTGGCACGGATCTGACGGGTGACAAAGCAGGGCCATCTGCACAGGAGCCTGGTAGTCAGACGCCCTTGAAGTCTATGC
TTGTCATCAGTGGAGGAGAGGGCTACATCGACTTCCGAATGGGTGATGAAGGTGGAGAATCAGAACTTCTTGGAGAGGATCTTCCACTTG
AACCTTCTGTCACCAAAGCAGAAAGGAGTCACTTGATAGTGTGGCAAGTGATGTATGGCAATGAGTGAGCCCATGGGAAACAGGTGGAGA
TGGGGAAGCCGTCTCTTCTGCATGGTTTATTTTCCCTCTATCCTTTTATTTAATGCTCTTTTGTGAGATAAGTTTCACCACATAATGTGT
GAGCATTTTTTCCTGTTAACTTTATATTACAAAATCCGTTCTACCATAACAATACAGAGGAACTAGCTGTGTTACTGCACCAGTGTTATA
GGTAACTTCAGTATATTATGAACAAATCAAAGAATGTTTACTTCCTGCAAACTGGTGAATTATAGAAAGCAATCCAGATGTGGTTTACTC
TGCCACAGTCTAATGTCATTCACTTCATTTGATGGGGTCACTTGTTAGCTGTCACTAATAATGGAATTAATGGGAAACACTTGATAAATG
AAACTGTACCGTTAAATACAATAGCTGAGTTTTCCCCAGTGTATTGTAAAATTGACACACACTAATACAAGATGGATTATCAGGATGTAT
CTAAATGTCCCGAGAGGGTTAAAAGCTAACTGTAAATTACTTTAACTTTCACTTTCAAATCTGACAAATCTTGTTTATATGGTATATAAA

>57135_57135_8_NADSYN1-SPAG9_NADSYN1_chr11_71193071_ENST00000539574_SPAG9_chr17_49048217_ENST00000357122_length(amino acids)=211AA_BP=124
MGISGQEVLTATLDLEDVRSYRAEISSRNLAASRASPYPRVKVDFALSCHEDLLAPISEPIEWKYHSPEEEISLGPACWLWDFLRRSQQA
GFLLPLSGGVDSAATACLIYSMCCQVCEAVRSGSQVISPQSSSSGTDLTGDKAGPSAQEPGSQTPLKSMLVISGGEGYIDFRMGDEGGES

--------------------------------------------------------------
>57135_57135_9_NADSYN1-SPAG9_NADSYN1_chr11_71193071_ENST00000539574_SPAG9_chr17_49048217_ENST00000505279_length(transcript)=2063nt_BP=1152nt
ATCATTAACCGCGACAGAGCTGGAAGGGCTTTGAAGAGAAGGATTAAGTTCCTGCTGATGGGAAGTGTGGTCCTCTCCCCGTTCACGTCA
GAGCCACAGGCACATTGGTGGTCGTGTTGATTGGCAGGTGTGTTGGCAATCAATCACCTGCCCCAGGACCCCCGCAGGTTCCCGGCCCCA
CATCAAGCCACCAAATCGGAGTCCTCGGGGGTCTGTATATTTAGTGAGCACCAGGCAGTTGTTTCGTGCATTAGAATCCGGGAGCCGTTG
CCTTACACGTCTCTAGAGTTCCTGATGTTGCCTGAGAGCTCCGTCGTAGGCTGTGGCCACAGGCCTGCTGTATTCAGAGTGGCCGCGCTG
TCCTCAGGCTCGGGCCACTGCCCTCCACCAGGTCCTCCGTGGTGCACCTGAAATGGTCAACAGAAGTCTTGTGACACGTGGAATCATTTC
AGAGTCACCCCTTCTGCCTCCTGCTCAAGCAACAGACCTGCCGATCACCCCCGTCGGGCCCGCGTTTCTCAGGGTCTTCCTAATCCCCTG
GGCTTTCCGGCTTGTCGTGTGCCTGGAGTCAGGCCGCCGTGCGGCAGGCTGTTAACCTAGCCTCGGGGAGAGTGGGATGGAGCCACCTTC
TCATGGAACGATCCTCGCCTTCCCTCATCTCCATTGTTTTATGGCTTCACACGGACCGTGGCTTTCTGCATGGAAGCTTGGTGGCCAGGG
TGCTGTCACTTTGGGAAGCAGCCAGAGAACCACAGGATGCGTGAATCGGTCTCCTTGTCTTCATGGGCATCTCCGGCCAGGAAGTCCTGA
CGGCCACGCTGGATCTGGAGGACGTCCGGAGCTACAGGGCGGAGATTTCATCTCGAAACCTGGCGGCCAGCAGGGCGAGCCCCTACCCCA
GAGTGAAGGTGGACTTTGCCCTCTCGTGCCACGAGGACTTGCTGGCACCCATCTCTGAGCCCATCGAGTGGAAATACCACAGCCCTGAGG
AGGAGATAAGCCTTGGACCTGCCTGCTGGCTCTGGGATTTTTTAAGACGAAGTCAACAGGCAGGGTTTTTGCTGCCCTTGAGTGGCGGGG
TGGACAGCGCAGCCACCGCCTGCCTCATCTACTCCATGTGCTGCCAGGTCTGCGAGGCCGTGAGGAGTGGAAGTCAAGTCATCAGCCCAC
AAAGTAGCAGTAGTGGCACGGATCTGACGGGTGACAAAGCAGGGCCATCTGCACAGGAGCCTGGTAGTCAGACGCCCTTGAAGTCTATGC
TTGTCATCAGTGGAGGAGAGGGCTACATCGACTTCCGAATGGGTGATGAAGGTGGAGAATCAGAACTTCTTGGAGAGGATCTTCCACTTG
AACCTTCTGTCACCAAAGCAGAAAGGAGTCACTTGATAGTGTGGCAAGTGATGTATGGCAATGAGTGAGCCCATGGGAAACAGGTGGAGA
TGGGGAAGCCGTCTCTTCTGCATGGTTTATTTTCCCTCTATCCTTTTATTTAATGCTCTTTTGTGAGATAAGTTTCACCACATAATGTGT
GAGCATTTTTTCCTGTTAACTTTATATTACAAAATCCGTTCTACCATAACAATACAGAGGAACTAGCTGTGTTACTGCACCAGTGTTATA
GGTAACTTCAGTATATTATGAACAAATCAAAGAATGTTTACTTCCTGCAAACTGGTGAATTATAGAAAGCAATCCAGATGTGGTTTACTC
TGCCACAGTCTAATGTCATTCACTTCATTTGATGGGGTCACTTGTTAGCTGTCACTAATAATGGAATTAATGGGAAACACTTGATAAATG
AAACTGTACCGTTAAATACAATAGCTGAGTTTTCCCCAGTGTATTGTAAAATTGACACACACTAATACAAGATGGATTATCAGGATGTAT
CTAAATGTCCCGAGAGGGTTAAAAGCTAACTGTAAATTACTTTAACTTTCACTTTCAAATCTGACAAATCTTGTTTATATGGTATATAAA

>57135_57135_9_NADSYN1-SPAG9_NADSYN1_chr11_71193071_ENST00000539574_SPAG9_chr17_49048217_ENST00000505279_length(amino acids)=211AA_BP=124
MGISGQEVLTATLDLEDVRSYRAEISSRNLAASRASPYPRVKVDFALSCHEDLLAPISEPIEWKYHSPEEEISLGPACWLWDFLRRSQQA
GFLLPLSGGVDSAATACLIYSMCCQVCEAVRSGSQVISPQSSSSGTDLTGDKAGPSAQEPGSQTPLKSMLVISGGEGYIDFRMGDEGGES

--------------------------------------------------------------

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Fusion Gene PPI Analysis for NADSYN1-SPAG9


check button Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in

ChiPPI page.


check button Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160)
HgeneHgene's interactorsTgeneTgene's interactors


check button - Retained PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenStill interaction with


check button - Lost PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


check button - Retained PPIs, but lost function due to frame-shift fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


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Related Drugs for NADSYN1-SPAG9


check button Drugs targeting genes involved in this fusion gene.
(DrugBank Version 5.1.8 2021-05-08)
PartnerGeneUniProtAccDrugBank IDDrug nameDrug activityDrug typeDrug status

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Related Diseases for NADSYN1-SPAG9


check button Diseases associated with fusion partners.
(DisGeNet 4.0)
PartnerGeneDisease IDDisease name# pubmedsSource