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Center for Computational Systems Medicine
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Fusion Gene Summary

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Fusion Gene ORF analysis

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Fusion Genomic Features

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Fusion Protein Features

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Fusion Gene Sequence

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Fusion Gene PPI analysis

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Related Drugs

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Related Diseases

Fusion gene:APTX-GNE (FusionGDB2 ID:5720)

Fusion Gene Summary for APTX-GNE

check button Fusion gene summary
Fusion gene informationFusion gene name: APTX-GNE
Fusion gene ID: 5720
HgeneTgene
Gene symbol

APTX

GNE

Gene ID

54840

10020

Gene nameaprataxinglucosamine (UDP-N-acetyl)-2-epimerase/N-acetylmannosamine kinase
SynonymsAOA|AOA1|AXA1|EAOH|EOAHA|FHA-HITDMRV|GLCNE|IBM2|NM|Uae1
Cytomap

9p21.1

9p13.3

Type of geneprotein-codingprotein-coding
Descriptionaprataxinforkhead-associated domain histidine triad-like proteinbifunctional UDP-N-acetylglucosamine 2-epimerase/N-acetylmannosamine kinaseN-acylmannosamine kinaseUDP-GlcNAc-2-epimerase/ManAc kinaseUDP-N-acetylglucosamine 2-epimerase/N-acetylmannosamine kinase
Modification date2020032020200328
UniProtAcc

Q7Z2E3

Q9Y223

Ensembl transtripts involved in fusion geneENST00000379813, ENST00000309615, 
ENST00000379819, ENST00000379825, 
ENST00000397172, ENST00000476858, 
ENST00000379817, ENST00000436040, 
ENST00000463596, ENST00000468275, 
ENST00000473270, 		ENST00000377902, 
ENST00000396594, ENST00000447283, 
ENST00000539208, ENST00000539815, 
ENST00000543356, 
Fusion gene scores* DoF score10 X 9 X 6=5403 X 3 X 3=27
# samples 124
** MAII scorelog2(12/540*10)=-2.16992500144231
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0		log2(4/27*10)=0.567040592723894
effective Gene in Pan-Cancer Fusion Genes (eGinPCFGs).
DoF>8 and MAII>0
Context

PubMed: APTX [Title/Abstract] AND GNE [Title/Abstract] AND fusion [Title/Abstract]

Most frequent breakpointAPTX(33001565)-GNE(36220017), # samples:3
Anticipated loss of major functional domain due to fusion event.APTX-GNE seems lost the major protein functional domain in Hgene partner, which is a essential gene due to the frame-shifted ORF.
APTX-GNE seems lost the major protein functional domain in Tgene partner, which is a cell metabolism gene due to the frame-shifted ORF.
* DoF score (Degree of Frequency) = # partners X # break points X # cancer types
** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)

check button Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez
PartnerGeneGO IDGO termPubMed ID
HgeneAPTX

GO:0000012

single strand break repair

17519253

HgeneAPTX

GO:0042542

response to hydrogen peroxide

15044383


check buttonFusion gene breakpoints across APTX (5'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.

check buttonFusion gene breakpoints across GNE (3'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.

check button Fusion gene information from two resources (ChiTars 5.0 and ChimerDB 4.0)
* All genome coordinats were lifted-over on hg19.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
SourceDiseaseSampleHgeneHchrHbpHstrandTgeneTchrTbpTstrand
ChimerDB4BRCATCGA-E2-A15H-01AAPTXchr9

33001565

-GNEchr9

36220017

-
ChimerDB4BRCATCGA-E2-A15HAPTXchr9

33001564

-GNEchr9

36220017

-


Top

Fusion Gene ORF analysis for APTX-GNE

check button Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
ORFHenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrand
5UTR-3CDSENST00000379813ENST00000377902APTXchr9

33001565

-GNEchr9

36220017

-
5UTR-3CDSENST00000379813ENST00000377902APTXchr9

33001564

-GNEchr9

36220017

-
5UTR-3CDSENST00000379813ENST00000396594APTXchr9

33001565

-GNEchr9

36220017

-
5UTR-3CDSENST00000379813ENST00000396594APTXchr9

33001564

-GNEchr9

36220017

-
5UTR-3CDSENST00000379813ENST00000447283APTXchr9

33001565

-GNEchr9

36220017

-
5UTR-3CDSENST00000379813ENST00000447283APTXchr9

33001564

-GNEchr9

36220017

-
5UTR-3CDSENST00000379813ENST00000539208APTXchr9

33001565

-GNEchr9

36220017

-
5UTR-3CDSENST00000379813ENST00000539208APTXchr9

33001564

-GNEchr9

36220017

-
5UTR-3CDSENST00000379813ENST00000539815APTXchr9

33001565

-GNEchr9

36220017

-
5UTR-3CDSENST00000379813ENST00000539815APTXchr9

33001564

-GNEchr9

36220017

-
5UTR-3CDSENST00000379813ENST00000543356APTXchr9

33001565

-GNEchr9

36220017

-
5UTR-3CDSENST00000379813ENST00000543356APTXchr9

33001564

-GNEchr9

36220017

-
Frame-shiftENST00000309615ENST00000377902APTXchr9

33001565

-GNEchr9

36220017

-
Frame-shiftENST00000309615ENST00000377902APTXchr9

33001564

-GNEchr9

36220017

-
Frame-shiftENST00000309615ENST00000396594APTXchr9

33001565

-GNEchr9

36220017

-
Frame-shiftENST00000309615ENST00000396594APTXchr9

33001564

-GNEchr9

36220017

-
Frame-shiftENST00000309615ENST00000447283APTXchr9

33001565

-GNEchr9

36220017

-
Frame-shiftENST00000309615ENST00000447283APTXchr9

33001564

-GNEchr9

36220017

-
Frame-shiftENST00000309615ENST00000539208APTXchr9

33001565

-GNEchr9

36220017

-
Frame-shiftENST00000309615ENST00000539208APTXchr9

33001564

-GNEchr9

36220017

-
Frame-shiftENST00000309615ENST00000539815APTXchr9

33001565

-GNEchr9

36220017

-
Frame-shiftENST00000309615ENST00000539815APTXchr9

33001564

-GNEchr9

36220017

-
Frame-shiftENST00000309615ENST00000543356APTXchr9

33001565

-GNEchr9

36220017

-
Frame-shiftENST00000309615ENST00000543356APTXchr9

33001564

-GNEchr9

36220017

-
Frame-shiftENST00000379819ENST00000377902APTXchr9

33001565

-GNEchr9

36220017

-
Frame-shiftENST00000379819ENST00000377902APTXchr9

33001564

-GNEchr9

36220017

-
Frame-shiftENST00000379819ENST00000396594APTXchr9

33001565

-GNEchr9

36220017

-
Frame-shiftENST00000379819ENST00000396594APTXchr9

33001564

-GNEchr9

36220017

-
Frame-shiftENST00000379819ENST00000447283APTXchr9

33001565

-GNEchr9

36220017

-
Frame-shiftENST00000379819ENST00000447283APTXchr9

33001564

-GNEchr9

36220017

-
Frame-shiftENST00000379819ENST00000539208APTXchr9

33001565

-GNEchr9

36220017

-
Frame-shiftENST00000379819ENST00000539208APTXchr9

33001564

-GNEchr9

36220017

-
Frame-shiftENST00000379819ENST00000539815APTXchr9

33001565

-GNEchr9

36220017

-
Frame-shiftENST00000379819ENST00000539815APTXchr9

33001564

-GNEchr9

36220017

-
Frame-shiftENST00000379819ENST00000543356APTXchr9

33001565

-GNEchr9

36220017

-
Frame-shiftENST00000379819ENST00000543356APTXchr9

33001564

-GNEchr9

36220017

-
Frame-shiftENST00000379825ENST00000377902APTXchr9

33001565

-GNEchr9

36220017

-
Frame-shiftENST00000379825ENST00000377902APTXchr9

33001564

-GNEchr9

36220017

-
Frame-shiftENST00000379825ENST00000396594APTXchr9

33001565

-GNEchr9

36220017

-
Frame-shiftENST00000379825ENST00000396594APTXchr9

33001564

-GNEchr9

36220017

-
Frame-shiftENST00000379825ENST00000447283APTXchr9

33001565

-GNEchr9

36220017

-
Frame-shiftENST00000379825ENST00000447283APTXchr9

33001564

-GNEchr9

36220017

-
Frame-shiftENST00000379825ENST00000539208APTXchr9

33001565

-GNEchr9

36220017

-
Frame-shiftENST00000379825ENST00000539208APTXchr9

33001564

-GNEchr9

36220017

-
Frame-shiftENST00000379825ENST00000539815APTXchr9

33001565

-GNEchr9

36220017

-
Frame-shiftENST00000379825ENST00000539815APTXchr9

33001564

-GNEchr9

36220017

-
Frame-shiftENST00000379825ENST00000543356APTXchr9

33001565

-GNEchr9

36220017

-
Frame-shiftENST00000379825ENST00000543356APTXchr9

33001564

-GNEchr9

36220017

-
Frame-shiftENST00000397172ENST00000377902APTXchr9

33001565

-GNEchr9

36220017

-
Frame-shiftENST00000397172ENST00000377902APTXchr9

33001564

-GNEchr9

36220017

-
Frame-shiftENST00000397172ENST00000396594APTXchr9

33001565

-GNEchr9

36220017

-
Frame-shiftENST00000397172ENST00000396594APTXchr9

33001564

-GNEchr9

36220017

-
Frame-shiftENST00000397172ENST00000447283APTXchr9

33001565

-GNEchr9

36220017

-
Frame-shiftENST00000397172ENST00000447283APTXchr9

33001564

-GNEchr9

36220017

-
Frame-shiftENST00000397172ENST00000539208APTXchr9

33001565

-GNEchr9

36220017

-
Frame-shiftENST00000397172ENST00000539208APTXchr9

33001564

-GNEchr9

36220017

-
Frame-shiftENST00000397172ENST00000539815APTXchr9

33001565

-GNEchr9

36220017

-
Frame-shiftENST00000397172ENST00000539815APTXchr9

33001564

-GNEchr9

36220017

-
Frame-shiftENST00000397172ENST00000543356APTXchr9

33001565

-GNEchr9

36220017

-
Frame-shiftENST00000397172ENST00000543356APTXchr9

33001564

-GNEchr9

36220017

-
Frame-shiftENST00000476858ENST00000377902APTXchr9

33001565

-GNEchr9

36220017

-
Frame-shiftENST00000476858ENST00000377902APTXchr9

33001564

-GNEchr9

36220017

-
Frame-shiftENST00000476858ENST00000396594APTXchr9

33001565

-GNEchr9

36220017

-
Frame-shiftENST00000476858ENST00000396594APTXchr9

33001564

-GNEchr9

36220017

-
Frame-shiftENST00000476858ENST00000447283APTXchr9

33001565

-GNEchr9

36220017

-
Frame-shiftENST00000476858ENST00000447283APTXchr9

33001564

-GNEchr9

36220017

-
Frame-shiftENST00000476858ENST00000539208APTXchr9

33001565

-GNEchr9

36220017

-
Frame-shiftENST00000476858ENST00000539208APTXchr9

33001564

-GNEchr9

36220017

-
Frame-shiftENST00000476858ENST00000539815APTXchr9

33001565

-GNEchr9

36220017

-
Frame-shiftENST00000476858ENST00000539815APTXchr9

33001564

-GNEchr9

36220017

-
Frame-shiftENST00000476858ENST00000543356APTXchr9

33001565

-GNEchr9

36220017

-
Frame-shiftENST00000476858ENST00000543356APTXchr9

33001564

-GNEchr9

36220017

-
intron-3CDSENST00000379817ENST00000377902APTXchr9

33001565

-GNEchr9

36220017

-
intron-3CDSENST00000379817ENST00000377902APTXchr9

33001564

-GNEchr9

36220017

-
intron-3CDSENST00000379817ENST00000396594APTXchr9

33001565

-GNEchr9

36220017

-
intron-3CDSENST00000379817ENST00000396594APTXchr9

33001564

-GNEchr9

36220017

-
intron-3CDSENST00000379817ENST00000447283APTXchr9

33001565

-GNEchr9

36220017

-
intron-3CDSENST00000379817ENST00000447283APTXchr9

33001564

-GNEchr9

36220017

-
intron-3CDSENST00000379817ENST00000539208APTXchr9

33001565

-GNEchr9

36220017

-
intron-3CDSENST00000379817ENST00000539208APTXchr9

33001564

-GNEchr9

36220017

-
intron-3CDSENST00000379817ENST00000539815APTXchr9

33001565

-GNEchr9

36220017

-
intron-3CDSENST00000379817ENST00000539815APTXchr9

33001564

-GNEchr9

36220017

-
intron-3CDSENST00000379817ENST00000543356APTXchr9

33001565

-GNEchr9

36220017

-
intron-3CDSENST00000379817ENST00000543356APTXchr9

33001564

-GNEchr9

36220017

-
intron-3CDSENST00000436040ENST00000377902APTXchr9

33001565

-GNEchr9

36220017

-
intron-3CDSENST00000436040ENST00000377902APTXchr9

33001564

-GNEchr9

36220017

-
intron-3CDSENST00000436040ENST00000396594APTXchr9

33001565

-GNEchr9

36220017

-
intron-3CDSENST00000436040ENST00000396594APTXchr9

33001564

-GNEchr9

36220017

-
intron-3CDSENST00000436040ENST00000447283APTXchr9

33001565

-GNEchr9

36220017

-
intron-3CDSENST00000436040ENST00000447283APTXchr9

33001564

-GNEchr9

36220017

-
intron-3CDSENST00000436040ENST00000539208APTXchr9

33001565

-GNEchr9

36220017

-
intron-3CDSENST00000436040ENST00000539208APTXchr9

33001564

-GNEchr9

36220017

-
intron-3CDSENST00000436040ENST00000539815APTXchr9

33001565

-GNEchr9

36220017

-
intron-3CDSENST00000436040ENST00000539815APTXchr9

33001564

-GNEchr9

36220017

-
intron-3CDSENST00000436040ENST00000543356APTXchr9

33001565

-GNEchr9

36220017

-
intron-3CDSENST00000436040ENST00000543356APTXchr9

33001564

-GNEchr9

36220017

-
intron-3CDSENST00000463596ENST00000377902APTXchr9

33001565

-GNEchr9

36220017

-
intron-3CDSENST00000463596ENST00000377902APTXchr9

33001564

-GNEchr9

36220017

-
intron-3CDSENST00000463596ENST00000396594APTXchr9

33001565

-GNEchr9

36220017

-
intron-3CDSENST00000463596ENST00000396594APTXchr9

33001564

-GNEchr9

36220017

-
intron-3CDSENST00000463596ENST00000447283APTXchr9

33001565

-GNEchr9

36220017

-
intron-3CDSENST00000463596ENST00000447283APTXchr9

33001564

-GNEchr9

36220017

-
intron-3CDSENST00000463596ENST00000539208APTXchr9

33001565

-GNEchr9

36220017

-
intron-3CDSENST00000463596ENST00000539208APTXchr9

33001564

-GNEchr9

36220017

-
intron-3CDSENST00000463596ENST00000539815APTXchr9

33001565

-GNEchr9

36220017

-
intron-3CDSENST00000463596ENST00000539815APTXchr9

33001564

-GNEchr9

36220017

-
intron-3CDSENST00000463596ENST00000543356APTXchr9

33001565

-GNEchr9

36220017

-
intron-3CDSENST00000463596ENST00000543356APTXchr9

33001564

-GNEchr9

36220017

-
intron-3CDSENST00000468275ENST00000377902APTXchr9

33001565

-GNEchr9

36220017

-
intron-3CDSENST00000468275ENST00000377902APTXchr9

33001564

-GNEchr9

36220017

-
intron-3CDSENST00000468275ENST00000396594APTXchr9

33001565

-GNEchr9

36220017

-
intron-3CDSENST00000468275ENST00000396594APTXchr9

33001564

-GNEchr9

36220017

-
intron-3CDSENST00000468275ENST00000447283APTXchr9

33001565

-GNEchr9

36220017

-
intron-3CDSENST00000468275ENST00000447283APTXchr9

33001564

-GNEchr9

36220017

-
intron-3CDSENST00000468275ENST00000539208APTXchr9

33001565

-GNEchr9

36220017

-
intron-3CDSENST00000468275ENST00000539208APTXchr9

33001564

-GNEchr9

36220017

-
intron-3CDSENST00000468275ENST00000539815APTXchr9

33001565

-GNEchr9

36220017

-
intron-3CDSENST00000468275ENST00000539815APTXchr9

33001564

-GNEchr9

36220017

-
intron-3CDSENST00000468275ENST00000543356APTXchr9

33001565

-GNEchr9

36220017

-
intron-3CDSENST00000468275ENST00000543356APTXchr9

33001564

-GNEchr9

36220017

-
intron-3CDSENST00000473270ENST00000377902APTXchr9

33001565

-GNEchr9

36220017

-
intron-3CDSENST00000473270ENST00000377902APTXchr9

33001564

-GNEchr9

36220017

-
intron-3CDSENST00000473270ENST00000396594APTXchr9

33001565

-GNEchr9

36220017

-
intron-3CDSENST00000473270ENST00000396594APTXchr9

33001564

-GNEchr9

36220017

-
intron-3CDSENST00000473270ENST00000447283APTXchr9

33001565

-GNEchr9

36220017

-
intron-3CDSENST00000473270ENST00000447283APTXchr9

33001564

-GNEchr9

36220017

-
intron-3CDSENST00000473270ENST00000539208APTXchr9

33001565

-GNEchr9

36220017

-
intron-3CDSENST00000473270ENST00000539208APTXchr9

33001564

-GNEchr9

36220017

-
intron-3CDSENST00000473270ENST00000539815APTXchr9

33001565

-GNEchr9

36220017

-
intron-3CDSENST00000473270ENST00000539815APTXchr9

33001564

-GNEchr9

36220017

-
intron-3CDSENST00000473270ENST00000543356APTXchr9

33001565

-GNEchr9

36220017

-
intron-3CDSENST00000473270ENST00000543356APTXchr9

33001564

-GNEchr9

36220017

-

check buttonORFfinder result based on the fusion transcript sequence of in-frame fusion genes.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandSeq length
(transcript)		BP loci
(transcript)		Predicted start
(transcript)		Predicted stop
(transcript)		Seq length
(amino acids)

check buttonDeepORF prediction of the coding potential based on the fusion transcript sequence of in-frame fusion genes. DeepORF is a coding potential classifier based on convolutional neural network by comparing the real Ribo-seq data. If the no-coding score < 0.5 and coding score > 0.5, then the in-frame fusion transcript is predicted as being likely translated.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandNo-coding scoreCoding score

Top

Fusion Genomic Features for APTX-GNE


check buttonFusionAI prediction of the potential fusion gene breakpoint based on the pre-mature RNA sequence context (+/- 5kb of individual partner genes, total 20kb length sequence). FusionAI is a fusion gene breakpoint classifier based on convolutional neural network by comparing the fusion positive and negative sequence context of ~ 20K fusion gene data. From here, we can have the relative potentency of the 20K genomic sequence how individual sequnce will be likely used as the gene fusion breakpoints.
HgeneHchrHbpHstrandTgeneTchrTbpTstrand1-pp (fusion gene breakpoint)

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions. We integrated a total of 44 different types of human genomic feature loci information across five big categories including virus integration sites, repeats, structural variants, chromatin states, and gene expression regulation. More details are in help page.

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions that are ovelapped with the top 1% feature importance score regions. More details are in help page.

Top

Fusion Protein Features for APTX-GNE


check button Four levels of functional features of fusion genes
Go to FGviewer search page for the most frequent breakpoint (https://ccsmweb.uth.edu/FGviewer/:33001565/:36220017)
- FGviewer provides the online visualization of the retention search of the protein functional features across DNA, RNA, protein, and pathological levels.
- How to search
1. Put your fusion gene symbol.
2. Press the tab key until there will be shown the breakpoint information filled.
4. Go down and press 'Search' tab twice.
4. Go down to have the hyperlink of the search result.
5. Click the hyperlink.
6. See the FGviewer result for your fusion gene.
FGviewer

check buttonMain function of each fusion partner protein. (from UniProt)
HgeneTgene
APTX

Q7Z2E3

GNE

Q9Y223

FUNCTION: DNA-binding protein involved in single-strand DNA break repair, double-strand DNA break repair and base excision repair (PubMed:15380105, PubMed:15044383, PubMed:16964241, PubMed:17276982, PubMed:24362567). Resolves abortive DNA ligation intermediates formed either at base excision sites, or when DNA ligases attempt to repair non-ligatable breaks induced by reactive oxygen species (PubMed:16964241, PubMed:24362567). Catalyzes the release of adenylate groups covalently linked to 5'-phosphate termini, resulting in the production of 5'-phosphate termini that can be efficiently rejoined (PubMed:16964241, PubMed:17276982, PubMed:24362567). Also able to hydrolyze adenosine 5'-monophosphoramidate (AMP-NH(2)) and diadenosine tetraphosphate (AppppA), but with lower catalytic activity (PubMed:16547001). Likewise, catalyzes the release of 3'-linked guanosine (DNAppG) and inosine (DNAppI) from DNA, but has higher specific activity with 5'-linked adenosine (AppDNA) (By similarity). {ECO:0000250|UniProtKB:O74859, ECO:0000269|PubMed:15044383, ECO:0000269|PubMed:15380105, ECO:0000269|PubMed:16547001, ECO:0000269|PubMed:16964241, ECO:0000269|PubMed:17276982, ECO:0000269|PubMed:24362567}.FUNCTION: Regulates and initiates biosynthesis of N-acetylneuraminic acid (NeuAc), a precursor of sialic acids. Plays an essential role in early development (By similarity). Required for normal sialylation in hematopoietic cells. Sialylation is implicated in cell adhesion, signal transduction, tumorigenicity and metastatic behavior of malignant cells. {ECO:0000250, ECO:0000269|PubMed:10334995}.

check buttonRetention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at

download page


* Minus value of BPloci means that the break pointn is located before the CDS.
- In-frame and retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note

- In-frame and not-retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note


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Fusion Gene Sequence for APTX-GNE


check button For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. To have fusion amino acid sequence, we ran ORFfinder and chose the longest ORF among the all predicted ones.

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Fusion Gene PPI Analysis for APTX-GNE


check button Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in

ChiPPI page.


check button Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160)
HgeneHgene's interactorsTgeneTgene's interactors


check button - Retained PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenStill interaction with


check button - Lost PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


check button - Retained PPIs, but lost function due to frame-shift fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


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Related Drugs for APTX-GNE


check button Drugs targeting genes involved in this fusion gene.
(DrugBank Version 5.1.8 2021-05-08)
PartnerGeneUniProtAccDrugBank IDDrug nameDrug activityDrug typeDrug status

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Related Diseases for APTX-GNE


check button Diseases associated with fusion partners.
(DisGeNet 4.0)
PartnerGeneDisease IDDisease name# pubmedsSource