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Center for Computational Systems Medicine
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Fusion Gene Summary

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Fusion Gene ORF analysis

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Fusion Genomic Features

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Fusion Protein Features

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Fusion Gene Sequence

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Fusion Gene PPI analysis

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Related Drugs

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Related Diseases

Fusion gene:NARF-OLFML2B (FusionGDB2 ID:57258)

Fusion Gene Summary for NARF-OLFML2B

check button Fusion gene summary
Fusion gene informationFusion gene name: NARF-OLFML2B
Fusion gene ID: 57258
HgeneTgene
Gene symbol

NARF

OLFML2B

Gene ID

51444

25903

Gene namering finger protein 138olfactomedin like 2B
SynonymsHSD-4|NARF|STRIN|hNARF-
Cytomap

18q12.1

1q23.3

Type of geneprotein-codingprotein-coding
DescriptionE3 ubiquitin-protein ligase RNF138NLK-associated RING finger proteinNemo-like kinase-associated RING finger proteinRING-type E3 ubiquitin transferase RNF138nemo-like kinase associated ring finger proteinring finger protein 138, E3 ubiquitin protein lolfactomedin-like protein 2Bphotomedin-2
Modification date2020031320200313
UniProtAcc..
Ensembl transtripts involved in fusion geneENST00000581743, ENST00000309794, 
ENST00000345415, ENST00000457415, 
ENST00000390006, ENST00000412079, 
ENST00000294794, ENST00000367940, 
ENST00000367938, 
Fusion gene scores* DoF score6 X 5 X 4=1203 X 3 X 2=18
# samples 63
** MAII scorelog2(6/120*10)=-1
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0		log2(3/18*10)=0.736965594166206
effective Gene in Pan-Cancer Fusion Genes (eGinPCFGs).
DoF>8 and MAII>0
Context

PubMed: NARF [Title/Abstract] AND OLFML2B [Title/Abstract] AND fusion [Title/Abstract]

Most frequent breakpointNARF(80417948)-OLFML2B(161989972), # samples:2
Anticipated loss of major functional domain due to fusion event.
* DoF score (Degree of Frequency) = # partners X # break points X # cancer types
** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)

check button Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez
PartnerGeneGO IDGO termPubMed ID

check buttonFusion gene breakpoints across NARF (5'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check buttonFusion gene breakpoints across OLFML2B (3'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check button Fusion gene information from two resources (ChiTars 5.0 and ChimerDB 4.0)
* All genome coordinats were lifted-over on hg19.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
SourceDiseaseSampleHgeneHchrHbpHstrandTgeneTchrTbpTstrand
ChimerDB4LUADTCGA-05-4432-01ANARFchr17

80417948

+OLFML2Bchr1

161989972

-


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Fusion Gene ORF analysis for NARF-OLFML2B

check button Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
ORFHenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrand
3UTR-3CDSENST00000581743ENST00000294794NARFchr17

80417948

+OLFML2Bchr1

161989972

-
3UTR-3CDSENST00000581743ENST00000367940NARFchr17

80417948

+OLFML2Bchr1

161989972

-
3UTR-intronENST00000581743ENST00000367938NARFchr17

80417948

+OLFML2Bchr1

161989972

-
5CDS-intronENST00000309794ENST00000367938NARFchr17

80417948

+OLFML2Bchr1

161989972

-
5CDS-intronENST00000345415ENST00000367938NARFchr17

80417948

+OLFML2Bchr1

161989972

-
5CDS-intronENST00000457415ENST00000367938NARFchr17

80417948

+OLFML2Bchr1

161989972

-
5UTR-3CDSENST00000390006ENST00000294794NARFchr17

80417948

+OLFML2Bchr1

161989972

-
5UTR-3CDSENST00000390006ENST00000367940NARFchr17

80417948

+OLFML2Bchr1

161989972

-
5UTR-3CDSENST00000412079ENST00000294794NARFchr17

80417948

+OLFML2Bchr1

161989972

-
5UTR-3CDSENST00000412079ENST00000367940NARFchr17

80417948

+OLFML2Bchr1

161989972

-
5UTR-intronENST00000390006ENST00000367938NARFchr17

80417948

+OLFML2Bchr1

161989972

-
5UTR-intronENST00000412079ENST00000367938NARFchr17

80417948

+OLFML2Bchr1

161989972

-
In-frameENST00000309794ENST00000294794NARFchr17

80417948

+OLFML2Bchr1

161989972

-
In-frameENST00000309794ENST00000367940NARFchr17

80417948

+OLFML2Bchr1

161989972

-
In-frameENST00000345415ENST00000294794NARFchr17

80417948

+OLFML2Bchr1

161989972

-
In-frameENST00000345415ENST00000367940NARFchr17

80417948

+OLFML2Bchr1

161989972

-
In-frameENST00000457415ENST00000294794NARFchr17

80417948

+OLFML2Bchr1

161989972

-
In-frameENST00000457415ENST00000367940NARFchr17

80417948

+OLFML2Bchr1

161989972

-

check buttonORFfinder result based on the fusion transcript sequence of in-frame fusion genes.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandSeq length
(transcript)		BP loci
(transcript)		Predicted start
(transcript)		Predicted stop
(transcript)		Seq length
(amino acids)
ENST00000309794NARFchr1780417948+ENST00000294794OLFML2Bchr1161989972-28683061982384728
ENST00000309794NARFchr1780417948+ENST00000367940OLFML2Bchr1161989972-26073061982387729
ENST00000345415NARFchr1780417948+ENST00000294794OLFML2Bchr1161989972-28252631552341728
ENST00000345415NARFchr1780417948+ENST00000367940OLFML2Bchr1161989972-25642631552344729
ENST00000457415NARFchr1780417948+ENST00000294794OLFML2Bchr1161989972-27712091012287728
ENST00000457415NARFchr1780417948+ENST00000367940OLFML2Bchr1161989972-25102091012290729

check buttonDeepORF prediction of the coding potential based on the fusion transcript sequence of in-frame fusion genes. DeepORF is a coding potential classifier based on convolutional neural network by comparing the real Ribo-seq data. If the no-coding score < 0.5 and coding score > 0.5, then the in-frame fusion transcript is predicted as being likely translated.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandNo-coding scoreCoding score
ENST00000309794ENST00000294794NARFchr1780417948+OLFML2Bchr1161989972-0.0121058360.9878941
ENST00000309794ENST00000367940NARFchr1780417948+OLFML2Bchr1161989972-0.0124706640.9875293
ENST00000345415ENST00000294794NARFchr1780417948+OLFML2Bchr1161989972-0.0133162990.98668367
ENST00000345415ENST00000367940NARFchr1780417948+OLFML2Bchr1161989972-0.0133192510.98668075
ENST00000457415ENST00000294794NARFchr1780417948+OLFML2Bchr1161989972-0.0138311240.98616886
ENST00000457415ENST00000367940NARFchr1780417948+OLFML2Bchr1161989972-0.013963120.98603684

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Fusion Genomic Features for NARF-OLFML2B


check buttonFusionAI prediction of the potential fusion gene breakpoint based on the pre-mature RNA sequence context (+/- 5kb of individual partner genes, total 20kb length sequence). FusionAI is a fusion gene breakpoint classifier based on convolutional neural network by comparing the fusion positive and negative sequence context of ~ 20K fusion gene data. From here, we can have the relative potentency of the 20K genomic sequence how individual sequnce will be likely used as the gene fusion breakpoints.
HgeneHchrHbpHstrandTgeneTchrTbpTstrand1-pp (fusion gene breakpoint)

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions. We integrated a total of 44 different types of human genomic feature loci information across five big categories including virus integration sites, repeats, structural variants, chromatin states, and gene expression regulation. More details are in help page.
genomic feature

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions that are ovelapped with the top 1% feature importance score regions. More details are in help page.

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Fusion Protein Features for NARF-OLFML2B


check button Four levels of functional features of fusion genes
Go to FGviewer search page for the most frequent breakpoint (https://ccsmweb.uth.edu/FGviewer/chr17:80417948/chr1:161989972)
- FGviewer provides the online visualization of the retention search of the protein functional features across DNA, RNA, protein, and pathological levels.
- How to search
1. Put your fusion gene symbol.
2. Press the tab key until there will be shown the breakpoint information filled.
4. Go down and press 'Search' tab twice.
4. Go down to have the hyperlink of the search result.
5. Click the hyperlink.
6. See the FGviewer result for your fusion gene.
FGviewer

check buttonMain function of each fusion partner protein. (from UniProt)
HgeneTgene
..
FUNCTION: Transcriptional activator which is required for calcium-dependent dendritic growth and branching in cortical neurons. Recruits CREB-binding protein (CREBBP) to nuclear bodies. Component of the CREST-BRG1 complex, a multiprotein complex that regulates promoter activation by orchestrating a calcium-dependent release of a repressor complex and a recruitment of an activator complex. In resting neurons, transcription of the c-FOS promoter is inhibited by BRG1-dependent recruitment of a phospho-RB1-HDAC1 repressor complex. Upon calcium influx, RB1 is dephosphorylated by calcineurin, which leads to release of the repressor complex. At the same time, there is increased recruitment of CREBBP to the promoter by a CREST-dependent mechanism, which leads to transcriptional activation. The CREST-BRG1 complex also binds to the NR2B promoter, and activity-dependent induction of NR2B expression involves a release of HDAC1 and recruitment of CREBBP (By similarity). {ECO:0000250}.FUNCTION: Transcriptional activator which is required for calcium-dependent dendritic growth and branching in cortical neurons. Recruits CREB-binding protein (CREBBP) to nuclear bodies. Component of the CREST-BRG1 complex, a multiprotein complex that regulates promoter activation by orchestrating a calcium-dependent release of a repressor complex and a recruitment of an activator complex. In resting neurons, transcription of the c-FOS promoter is inhibited by BRG1-dependent recruitment of a phospho-RB1-HDAC1 repressor complex. Upon calcium influx, RB1 is dephosphorylated by calcineurin, which leads to release of the repressor complex. At the same time, there is increased recruitment of CREBBP to the promoter by a CREST-dependent mechanism, which leads to transcriptional activation. The CREST-BRG1 complex also binds to the NR2B promoter, and activity-dependent induction of NR2B expression involves a release of HDAC1 and recruitment of CREBBP (By similarity). {ECO:0000250}.

check buttonRetention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at

download page


* Minus value of BPloci means that the break pointn is located before the CDS.
- In-frame and retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
TgeneOLFML2Bchr17:80417948chr1:161989972ENST0000029479408179_21358751.0Coiled coilOntology_term=ECO:0000255
TgeneOLFML2Bchr17:80417948chr1:161989972ENST0000036793802179_2130234.0Coiled coilOntology_term=ECO:0000255
TgeneOLFML2Bchr17:80417948chr1:161989972ENST000003679380240_680234.0Coiled coilOntology_term=ECO:0000255
TgeneOLFML2Bchr17:80417948chr1:161989972ENST0000029479408233_23858751.0Compositional biasNote=Poly-Ala
TgeneOLFML2Bchr17:80417948chr1:161989972ENST0000036793802233_2380234.0Compositional biasNote=Poly-Ala
TgeneOLFML2Bchr17:80417948chr1:161989972ENST0000029479408493_75058751.0DomainOlfactomedin-like
TgeneOLFML2Bchr17:80417948chr1:161989972ENST0000036793802493_7500234.0DomainOlfactomedin-like

- In-frame and not-retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
TgeneOLFML2Bchr17:80417948chr1:161989972ENST000002947940840_6858751.0Coiled coilOntology_term=ECO:0000255


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Fusion Gene Sequence for NARF-OLFML2B


check button For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. To have fusion amino acid sequence, we ran ORFfinder and chose the longest ORF among the all predicted ones.
>57258_57258_1_NARF-OLFML2B_NARF_chr17_80417948_ENST00000309794_OLFML2B_chr1_161989972_ENST00000294794_length(transcript)=2868nt_BP=306nt
GTAAGGGTGGGGAATCCTATTGGCCCAGGGGTGCGGCTTGTCCTCTCCCGGTGCTCTCATTGGCCGAGCGCGGCCGTTGGGGGTGAGGCC
GCGTCGGGGGAGGACAACAAAGGGCCGCGGGCGGCGGGCAGTGGTGTCCCAGTCTCCCGGTGCTTCCCTGAGGCTGAGGCGCCCGGCCTC
CCGCCCGCCGCGCTCCAGATGAAGTGTGAGCACTGCACGCGCAAGGAATGTAGTAAGAAAACAAAAACTGATGACCAAGAGAATGTGTCA
GCCGATGCACCGAGTCCAGCCCAGGAAAATGGAGAGTTGCTGGGGGACTATGACAAGGTCAAGGCTATGTCTGAGGGCTCGGACTGTCAG
TGCAAGTGTGTGGTGAGACCCCTGGGCCGGGATGCCTGCCAGAGGATCAATGCGGGGGCCTCCAGGAAGGAAGACTTCTATACCGTGGAA
ACCATCACCTCAGGCTCGTCGTGCAAGTGTGCCTGTGTAGCACCCCCATCGGCCCTCAATCCCTGCGAGGGAGACTTCAGGCTCCAGAAG
CTGCGGGAGGCAGACAGCCAGGACTTGAAGCTCTCCACAATCATAGACATGTTGGAAGGAGCGTTCTATGGCCTGGATCTCCTGAAGCTA
CATTCAGTCACCACCAAACTGGTGGGGCGAGTGGATAAACTGGAGGAGGAAGTGTCTAAAAACCTCACCAAGGAAAATGAACAAATCAAA
GAGGACATGGAAGAAATTCGAACCGAGATGAATAAGCGAGGCAAAGAAAATTGCTCTGAAAACATCCTAGATAGCATGCCAGACATCCGC
TCAGCCCTGCAGAGGGATGCAGCAGCAGCCTACGCCCACCCAGAGTATGAAGAGCGGTTTCTGCAGGAAGAAACCGTGTCCCAGCAGATC
AACTCCATCGAACTTCTGCAGACGCGACCCCTGGCTCTGCCTGAGGTGGTGAAGTCACAGCGGCCCCTGCAGAGGCAGGTCCACCTGAGA
GGCCGGCCGGCCTCCCAGCCCACTGTCATCCGGGGCATCACCTACTATAAAGCCAAGGTCTCTGAAGAAGAGAATGACATTGAAGAGCAG
CAAGATGAGTTTTTCAGCGGTGACAATGGAGTGGATTTGCTGATTGAAGATCAGCTCCTGAGACACAACGGCCTGATGACCAGTGTCACC
CGGAGGCCTGCAGCCACCCGTCAGGGACACAGCACTGCTGTGACAAGCGACCTGAACGCTCGGACCGCACCCTGGTCCTCAGCACTGCCA
CAGCCCTCGACCTCAGATCCCAGCATCGCCAACCATGCCTCAGTGGGACCAACACTCCAAACAACCTCGGTGTCTCCAGATCCCACAAGG
GAGTCAGTCCTGCAGCCTTCTCCTCAGGTACCAGCCACCACTGTGGCCCACACAGCCACCCAGCAACCAGCAGCCCCAGCTCCTCCGGCA
GTGTCTCCCAGGGAGGCATTGATGGAAGCTATGCACACAGTCCCAGTGCCTCCCACCACAGTCAGAACAGACTCGCTGGGGAAAGATGCT
CCTGCTGGGTGGGGAACAACCCCTGCCAGCCCCACGCTGAGCCCCGAAGAAGAAGATGACATCCGGAATGTCATAGGAAGGTGCAAGGAC
ACTCTCTCCACAATCACGGGGCCGACCACCCAGAACACATATGGGCGGAATGAAGGGGCCTGGATGAAGGACCCCCTGGCCAAGGATGAG
CGGATTTACGTAACCAACTATTACTACGGCAACACCCTGGTAGAGTTCCGGAACCTGGAGAACTTCAAACAAGGTCGCTGGAGCAATTCC
TACAAGCTCCCGTACAGCTGGATCGGCACAGGCCACGTGGTATACAATGGCGCCTTCTACTACAATCGCGCCTTCACCCGCAACATCATC
AAGTACGACCTGAAGCAGCGCTACGTGGCTGCCTGGGCCATGCTGCATGACGTGGCCTACGAGGAGGCCACCCCCTGGCGATGGCAGGGC
CACTCAGACGTGGACTTTGCTGTGGACGAGAATGGCCTATGGCTCATCTACCCGGCCCTGGACGATGAGGGCTTCAGCCAGGAGGTCATT
GTCCTGAGCAAGCTCAATGCCGCGGACCTGAGCACACAGAAGGAGACCACATGGCGCACGGGGCTCCGGAGGAATTTCTACGGCAACTGC
TTCGTCATCTGTGGGGTGCTGTATGCCGTGGATAGCTACAACCAGCGGAATGCCAACATCTCCTACGCTTTCGACACCCACACCAACACA
CAGATCGTCCCCAGGCTGCTGTTCGAGAATGAGTATTCCTATACGACCCAGATAGACTACAACCCCAAGGACCGCCTGCTCTATGCCTGG
GACAATGGCCACCAGGTCACTTACCATGTCATCTTTGCCTACTGACACCCTTGTCCCCACAAGCAGAAGCACAGAGGGGTCACTAGCACC
TTGTGTGTATGTGTGTGCGCGCACGTGTGTGTAGGTGGGTATGTGTTGTTTAAAAATATATATTATTTTGTATAATATTGCAAATGTAAA
ATGACAATTTGGGTCTATTTTTTTATATGGATTGTAGATCAATCCATACGTGTATGTGCTGGTCTCATCCTCCCCAGTTTATATTTTTGT
GCAAATGAACTTCTCCTTTTGACCAGTAACCACCTTCCTTCAAGCCTTCAGCCCCTCCAGCTCCAAGTCTCAGATCTCGACCATTGAAAA
GGTTTCTTCATCTGGGTCTTGCAGGAGGCAGGCAACACCAGGAGCAGAAATGAAAGAGGCAAGAAAGAAGTGCTATGTGGCGAGAAAAAA

>57258_57258_1_NARF-OLFML2B_NARF_chr17_80417948_ENST00000309794_OLFML2B_chr1_161989972_ENST00000294794_length(amino acids)=728AA_BP=36
MKCEHCTRKECSKKTKTDDQENVSADAPSPAQENGELLGDYDKVKAMSEGSDCQCKCVVRPLGRDACQRINAGASRKEDFYTVETITSGS
SCKCACVAPPSALNPCEGDFRLQKLREADSQDLKLSTIIDMLEGAFYGLDLLKLHSVTTKLVGRVDKLEEEVSKNLTKENEQIKEDMEEI
RTEMNKRGKENCSENILDSMPDIRSALQRDAAAAYAHPEYEERFLQEETVSQQINSIELLQTRPLALPEVVKSQRPLQRQVHLRGRPASQ
PTVIRGITYYKAKVSEEENDIEEQQDEFFSGDNGVDLLIEDQLLRHNGLMTSVTRRPAATRQGHSTAVTSDLNARTAPWSSALPQPSTSD
PSIANHASVGPTLQTTSVSPDPTRESVLQPSPQVPATTVAHTATQQPAAPAPPAVSPREALMEAMHTVPVPPTTVRTDSLGKDAPAGWGT
TPASPTLSPEEEDDIRNVIGRCKDTLSTITGPTTQNTYGRNEGAWMKDPLAKDERIYVTNYYYGNTLVEFRNLENFKQGRWSNSYKLPYS
WIGTGHVVYNGAFYYNRAFTRNIIKYDLKQRYVAAWAMLHDVAYEEATPWRWQGHSDVDFAVDENGLWLIYPALDDEGFSQEVIVLSKLN
AADLSTQKETTWRTGLRRNFYGNCFVICGVLYAVDSYNQRNANISYAFDTHTNTQIVPRLLFENEYSYTTQIDYNPKDRLLYAWDNGHQV

--------------------------------------------------------------
>57258_57258_2_NARF-OLFML2B_NARF_chr17_80417948_ENST00000309794_OLFML2B_chr1_161989972_ENST00000367940_length(transcript)=2607nt_BP=306nt
GTAAGGGTGGGGAATCCTATTGGCCCAGGGGTGCGGCTTGTCCTCTCCCGGTGCTCTCATTGGCCGAGCGCGGCCGTTGGGGGTGAGGCC
GCGTCGGGGGAGGACAACAAAGGGCCGCGGGCGGCGGGCAGTGGTGTCCCAGTCTCCCGGTGCTTCCCTGAGGCTGAGGCGCCCGGCCTC
CCGCCCGCCGCGCTCCAGATGAAGTGTGAGCACTGCACGCGCAAGGAATGTAGTAAGAAAACAAAAACTGATGACCAAGAGAATGTGTCA
GCCGATGCACCGAGTCCAGCCCAGGAAAATGGAGAGTTGCTGGGGGACTATGACAAGGTCAAGGCTATGTCTGAGGGCTCGGACTGTCAG
TGCAAGTGTGTGGTGAGACCCCTGGGCCGGGATGCCTGCCAGAGGATCAATGCGGGGGCCTCCAGGAAGGAAGACTTCTATACCGTGGAA
ACCATCACCTCAGGCTCGTCGTGCAAGTGTGCCTGTGTAGCACCCCCATCGGCCCTCAATCCCTGCGAGGGAGACTTCAGGCTCCAGAAG
CTGCGGGAGGCAGACAGCCAGGACTTGAAGCTCTCCACAATCATAGACATGTTGGAAGGAGCGTTCTATGGCCTGGATCTCCTGAAGCTA
CATTCAGTCACCACCAAACTGGTGGGGCGAGTGGATAAACTGGAGGAGGAAGTGTCTAAAAACCTCACCAAGGAAAATGAACAAATCAAA
GAGGACATGGAAGAAATTCGAACCGAGATGAATAAGCGAGGCAAAGAAAATTGCTCTGAAAACATCCTAGATAGCATGCCAGACATCCGC
TCAGCCCTGCAGAGGGATGCAGCAGCAGCCTACGCCCACCCAGAGCAGTATGAAGAGCGGTTTCTGCAGGAAGAAACCGTGTCCCAGCAG
ATCAACTCCATCGAACTTCTGCAGACGCGACCCCTGGCTCTGCCTGAGGTGGTGAAGTCACAGCGGCCCCTGCAGAGGCAGGTCCACCTG
AGAGGCCGGCCGGCCTCCCAGCCCACTGTCATCCGGGGCATCACCTACTATAAAGCCAAGGTCTCTGAAGAAGAGAATGACATTGAAGAG
CAGCAAGATGAGTTTTTCAGCGGTGACAATGGAGTGGATTTGCTGATTGAAGATCAGCTCCTGAGACACAACGGCCTGATGACCAGTGTC
ACCCGGAGGCCTGCAGCCACCCGTCAGGGACACAGCACTGCTGTGACAAGCGACCTGAACGCTCGGACCGCACCCTGGTCCTCAGCACTG
CCACAGCCCTCGACCTCAGATCCCAGCATCGCCAACCATGCCTCAGTGGGACCAACACTCCAAACAACCTCGGTGTCTCCAGATCCCACA
AGGGAGTCAGTCCTGCAGCCTTCTCCTCAGGTACCAGCCACCACTGTGGCCCACACAGCCACCCAGCAACCAGCAGCCCCAGCTCCTCCG
GCAGTGTCTCCCAGGGAGGCATTGATGGAAGCTATGCACACAGTCCCAGTGCCTCCCACCACAGTCAGAACAGACTCGCTGGGGAAAGAT
GCTCCTGCTGGGTGGGGAACAACCCCTGCCAGCCCCACGCTGAGCCCCGAAGAAGAAGATGACATCCGGAATGTCATAGGAAGGTGCAAG
GACACTCTCTCCACAATCACGGGGCCGACCACCCAGAACACATATGGGCGGAATGAAGGGGCCTGGATGAAGGACCCCCTGGCCAAGGAT
GAGCGGATTTACGTAACCAACTATTACTACGGCAACACCCTGGTAGAGTTCCGGAACCTGGAGAACTTCAAACAAGGTCGCTGGAGCAAT
TCCTACAAGCTCCCGTACAGCTGGATCGGCACAGGCCACGTGGTATACAATGGCGCCTTCTACTACAATCGCGCCTTCACCCGCAACATC
ATCAAGTACGACCTGAAGCAGCGCTACGTGGCTGCCTGGGCCATGCTGCATGACGTGGCCTACGAGGAGGCCACCCCCTGGCGATGGCAG
GGCCACTCAGACGTGGACTTTGCTGTGGACGAGAATGGCCTATGGCTCATCTACCCGGCCCTGGACGATGAGGGCTTCAGCCAGGAGGTC
ATTGTCCTGAGCAAGCTCAATGCCGCGGACCTGAGCACACAGAAGGAGACCACATGGCGCACGGGGCTCCGGAGGAATTTCTACGGCAAC
TGCTTCGTCATCTGTGGGGTGCTGTATGCCGTGGATAGCTACAACCAGCGGAATGCCAACATCTCCTACGCTTTCGACACCCACACCAAC
ACACAGATCGTCCCCAGGCTGCTGTTCGAGAATGAGTATTCCTATACGACCCAGATAGACTACAACCCCAAGGACCGCCTGCTCTATGCC
TGGGACAATGGCCACCAGGTCACTTACCATGTCATCTTTGCCTACTGACACCCTTGTCCCCACAAGCAGAAGCACAGAGGGGTCACTAGC
ACCTTGTGTGTATGTGTGTGCGCGCACGTGTGTGTAGGTGGGTATGTGTTGTTTAAAAATATATATTATTTTGTATAATATTGCAAATGT

>57258_57258_2_NARF-OLFML2B_NARF_chr17_80417948_ENST00000309794_OLFML2B_chr1_161989972_ENST00000367940_length(amino acids)=729AA_BP=36
MKCEHCTRKECSKKTKTDDQENVSADAPSPAQENGELLGDYDKVKAMSEGSDCQCKCVVRPLGRDACQRINAGASRKEDFYTVETITSGS
SCKCACVAPPSALNPCEGDFRLQKLREADSQDLKLSTIIDMLEGAFYGLDLLKLHSVTTKLVGRVDKLEEEVSKNLTKENEQIKEDMEEI
RTEMNKRGKENCSENILDSMPDIRSALQRDAAAAYAHPEQYEERFLQEETVSQQINSIELLQTRPLALPEVVKSQRPLQRQVHLRGRPAS
QPTVIRGITYYKAKVSEEENDIEEQQDEFFSGDNGVDLLIEDQLLRHNGLMTSVTRRPAATRQGHSTAVTSDLNARTAPWSSALPQPSTS
DPSIANHASVGPTLQTTSVSPDPTRESVLQPSPQVPATTVAHTATQQPAAPAPPAVSPREALMEAMHTVPVPPTTVRTDSLGKDAPAGWG
TTPASPTLSPEEEDDIRNVIGRCKDTLSTITGPTTQNTYGRNEGAWMKDPLAKDERIYVTNYYYGNTLVEFRNLENFKQGRWSNSYKLPY
SWIGTGHVVYNGAFYYNRAFTRNIIKYDLKQRYVAAWAMLHDVAYEEATPWRWQGHSDVDFAVDENGLWLIYPALDDEGFSQEVIVLSKL
NAADLSTQKETTWRTGLRRNFYGNCFVICGVLYAVDSYNQRNANISYAFDTHTNTQIVPRLLFENEYSYTTQIDYNPKDRLLYAWDNGHQ

--------------------------------------------------------------
>57258_57258_3_NARF-OLFML2B_NARF_chr17_80417948_ENST00000345415_OLFML2B_chr1_161989972_ENST00000294794_length(transcript)=2825nt_BP=263nt
TCTCCCGGTGCTCTCATTGGCCGAGCGCGGCCGTTGGGGGTGAGGCCGCGTCGGGGGAGGACAACAAAGGGCCGCGGGCGGCGGGCAGTG
GTGTCCCAGTCTCCCGGTGCTTCCCTGAGGCTGAGGCGCCCGGCCTCCCGCCCGCCGCGCTCCAGATGAAGTGTGAGCACTGCACGCGCA
AGGAATGTAGTAAGAAAACAAAAACTGATGACCAAGAGAATGTGTCAGCCGATGCACCGAGTCCAGCCCAGGAAAATGGAGAGTTGCTGG
GGGACTATGACAAGGTCAAGGCTATGTCTGAGGGCTCGGACTGTCAGTGCAAGTGTGTGGTGAGACCCCTGGGCCGGGATGCCTGCCAGA
GGATCAATGCGGGGGCCTCCAGGAAGGAAGACTTCTATACCGTGGAAACCATCACCTCAGGCTCGTCGTGCAAGTGTGCCTGTGTAGCAC
CCCCATCGGCCCTCAATCCCTGCGAGGGAGACTTCAGGCTCCAGAAGCTGCGGGAGGCAGACAGCCAGGACTTGAAGCTCTCCACAATCA
TAGACATGTTGGAAGGAGCGTTCTATGGCCTGGATCTCCTGAAGCTACATTCAGTCACCACCAAACTGGTGGGGCGAGTGGATAAACTGG
AGGAGGAAGTGTCTAAAAACCTCACCAAGGAAAATGAACAAATCAAAGAGGACATGGAAGAAATTCGAACCGAGATGAATAAGCGAGGCA
AAGAAAATTGCTCTGAAAACATCCTAGATAGCATGCCAGACATCCGCTCAGCCCTGCAGAGGGATGCAGCAGCAGCCTACGCCCACCCAG
AGTATGAAGAGCGGTTTCTGCAGGAAGAAACCGTGTCCCAGCAGATCAACTCCATCGAACTTCTGCAGACGCGACCCCTGGCTCTGCCTG
AGGTGGTGAAGTCACAGCGGCCCCTGCAGAGGCAGGTCCACCTGAGAGGCCGGCCGGCCTCCCAGCCCACTGTCATCCGGGGCATCACCT
ACTATAAAGCCAAGGTCTCTGAAGAAGAGAATGACATTGAAGAGCAGCAAGATGAGTTTTTCAGCGGTGACAATGGAGTGGATTTGCTGA
TTGAAGATCAGCTCCTGAGACACAACGGCCTGATGACCAGTGTCACCCGGAGGCCTGCAGCCACCCGTCAGGGACACAGCACTGCTGTGA
CAAGCGACCTGAACGCTCGGACCGCACCCTGGTCCTCAGCACTGCCACAGCCCTCGACCTCAGATCCCAGCATCGCCAACCATGCCTCAG
TGGGACCAACACTCCAAACAACCTCGGTGTCTCCAGATCCCACAAGGGAGTCAGTCCTGCAGCCTTCTCCTCAGGTACCAGCCACCACTG
TGGCCCACACAGCCACCCAGCAACCAGCAGCCCCAGCTCCTCCGGCAGTGTCTCCCAGGGAGGCATTGATGGAAGCTATGCACACAGTCC
CAGTGCCTCCCACCACAGTCAGAACAGACTCGCTGGGGAAAGATGCTCCTGCTGGGTGGGGAACAACCCCTGCCAGCCCCACGCTGAGCC
CCGAAGAAGAAGATGACATCCGGAATGTCATAGGAAGGTGCAAGGACACTCTCTCCACAATCACGGGGCCGACCACCCAGAACACATATG
GGCGGAATGAAGGGGCCTGGATGAAGGACCCCCTGGCCAAGGATGAGCGGATTTACGTAACCAACTATTACTACGGCAACACCCTGGTAG
AGTTCCGGAACCTGGAGAACTTCAAACAAGGTCGCTGGAGCAATTCCTACAAGCTCCCGTACAGCTGGATCGGCACAGGCCACGTGGTAT
ACAATGGCGCCTTCTACTACAATCGCGCCTTCACCCGCAACATCATCAAGTACGACCTGAAGCAGCGCTACGTGGCTGCCTGGGCCATGC
TGCATGACGTGGCCTACGAGGAGGCCACCCCCTGGCGATGGCAGGGCCACTCAGACGTGGACTTTGCTGTGGACGAGAATGGCCTATGGC
TCATCTACCCGGCCCTGGACGATGAGGGCTTCAGCCAGGAGGTCATTGTCCTGAGCAAGCTCAATGCCGCGGACCTGAGCACACAGAAGG
AGACCACATGGCGCACGGGGCTCCGGAGGAATTTCTACGGCAACTGCTTCGTCATCTGTGGGGTGCTGTATGCCGTGGATAGCTACAACC
AGCGGAATGCCAACATCTCCTACGCTTTCGACACCCACACCAACACACAGATCGTCCCCAGGCTGCTGTTCGAGAATGAGTATTCCTATA
CGACCCAGATAGACTACAACCCCAAGGACCGCCTGCTCTATGCCTGGGACAATGGCCACCAGGTCACTTACCATGTCATCTTTGCCTACT
GACACCCTTGTCCCCACAAGCAGAAGCACAGAGGGGTCACTAGCACCTTGTGTGTATGTGTGTGCGCGCACGTGTGTGTAGGTGGGTATG
TGTTGTTTAAAAATATATATTATTTTGTATAATATTGCAAATGTAAAATGACAATTTGGGTCTATTTTTTTATATGGATTGTAGATCAAT
CCATACGTGTATGTGCTGGTCTCATCCTCCCCAGTTTATATTTTTGTGCAAATGAACTTCTCCTTTTGACCAGTAACCACCTTCCTTCAA
GCCTTCAGCCCCTCCAGCTCCAAGTCTCAGATCTCGACCATTGAAAAGGTTTCTTCATCTGGGTCTTGCAGGAGGCAGGCAACACCAGGA
GCAGAAATGAAAGAGGCAAGAAAGAAGTGCTATGTGGCGAGAAAAAAAGTTTTAATGTATTGGAGAAGTTTTAAAAAACCCAGAAAAACG

>57258_57258_3_NARF-OLFML2B_NARF_chr17_80417948_ENST00000345415_OLFML2B_chr1_161989972_ENST00000294794_length(amino acids)=728AA_BP=36
MKCEHCTRKECSKKTKTDDQENVSADAPSPAQENGELLGDYDKVKAMSEGSDCQCKCVVRPLGRDACQRINAGASRKEDFYTVETITSGS
SCKCACVAPPSALNPCEGDFRLQKLREADSQDLKLSTIIDMLEGAFYGLDLLKLHSVTTKLVGRVDKLEEEVSKNLTKENEQIKEDMEEI
RTEMNKRGKENCSENILDSMPDIRSALQRDAAAAYAHPEYEERFLQEETVSQQINSIELLQTRPLALPEVVKSQRPLQRQVHLRGRPASQ
PTVIRGITYYKAKVSEEENDIEEQQDEFFSGDNGVDLLIEDQLLRHNGLMTSVTRRPAATRQGHSTAVTSDLNARTAPWSSALPQPSTSD
PSIANHASVGPTLQTTSVSPDPTRESVLQPSPQVPATTVAHTATQQPAAPAPPAVSPREALMEAMHTVPVPPTTVRTDSLGKDAPAGWGT
TPASPTLSPEEEDDIRNVIGRCKDTLSTITGPTTQNTYGRNEGAWMKDPLAKDERIYVTNYYYGNTLVEFRNLENFKQGRWSNSYKLPYS
WIGTGHVVYNGAFYYNRAFTRNIIKYDLKQRYVAAWAMLHDVAYEEATPWRWQGHSDVDFAVDENGLWLIYPALDDEGFSQEVIVLSKLN
AADLSTQKETTWRTGLRRNFYGNCFVICGVLYAVDSYNQRNANISYAFDTHTNTQIVPRLLFENEYSYTTQIDYNPKDRLLYAWDNGHQV

--------------------------------------------------------------
>57258_57258_4_NARF-OLFML2B_NARF_chr17_80417948_ENST00000345415_OLFML2B_chr1_161989972_ENST00000367940_length(transcript)=2564nt_BP=263nt
TCTCCCGGTGCTCTCATTGGCCGAGCGCGGCCGTTGGGGGTGAGGCCGCGTCGGGGGAGGACAACAAAGGGCCGCGGGCGGCGGGCAGTG
GTGTCCCAGTCTCCCGGTGCTTCCCTGAGGCTGAGGCGCCCGGCCTCCCGCCCGCCGCGCTCCAGATGAAGTGTGAGCACTGCACGCGCA
AGGAATGTAGTAAGAAAACAAAAACTGATGACCAAGAGAATGTGTCAGCCGATGCACCGAGTCCAGCCCAGGAAAATGGAGAGTTGCTGG
GGGACTATGACAAGGTCAAGGCTATGTCTGAGGGCTCGGACTGTCAGTGCAAGTGTGTGGTGAGACCCCTGGGCCGGGATGCCTGCCAGA
GGATCAATGCGGGGGCCTCCAGGAAGGAAGACTTCTATACCGTGGAAACCATCACCTCAGGCTCGTCGTGCAAGTGTGCCTGTGTAGCAC
CCCCATCGGCCCTCAATCCCTGCGAGGGAGACTTCAGGCTCCAGAAGCTGCGGGAGGCAGACAGCCAGGACTTGAAGCTCTCCACAATCA
TAGACATGTTGGAAGGAGCGTTCTATGGCCTGGATCTCCTGAAGCTACATTCAGTCACCACCAAACTGGTGGGGCGAGTGGATAAACTGG
AGGAGGAAGTGTCTAAAAACCTCACCAAGGAAAATGAACAAATCAAAGAGGACATGGAAGAAATTCGAACCGAGATGAATAAGCGAGGCA
AAGAAAATTGCTCTGAAAACATCCTAGATAGCATGCCAGACATCCGCTCAGCCCTGCAGAGGGATGCAGCAGCAGCCTACGCCCACCCAG
AGCAGTATGAAGAGCGGTTTCTGCAGGAAGAAACCGTGTCCCAGCAGATCAACTCCATCGAACTTCTGCAGACGCGACCCCTGGCTCTGC
CTGAGGTGGTGAAGTCACAGCGGCCCCTGCAGAGGCAGGTCCACCTGAGAGGCCGGCCGGCCTCCCAGCCCACTGTCATCCGGGGCATCA
CCTACTATAAAGCCAAGGTCTCTGAAGAAGAGAATGACATTGAAGAGCAGCAAGATGAGTTTTTCAGCGGTGACAATGGAGTGGATTTGC
TGATTGAAGATCAGCTCCTGAGACACAACGGCCTGATGACCAGTGTCACCCGGAGGCCTGCAGCCACCCGTCAGGGACACAGCACTGCTG
TGACAAGCGACCTGAACGCTCGGACCGCACCCTGGTCCTCAGCACTGCCACAGCCCTCGACCTCAGATCCCAGCATCGCCAACCATGCCT
CAGTGGGACCAACACTCCAAACAACCTCGGTGTCTCCAGATCCCACAAGGGAGTCAGTCCTGCAGCCTTCTCCTCAGGTACCAGCCACCA
CTGTGGCCCACACAGCCACCCAGCAACCAGCAGCCCCAGCTCCTCCGGCAGTGTCTCCCAGGGAGGCATTGATGGAAGCTATGCACACAG
TCCCAGTGCCTCCCACCACAGTCAGAACAGACTCGCTGGGGAAAGATGCTCCTGCTGGGTGGGGAACAACCCCTGCCAGCCCCACGCTGA
GCCCCGAAGAAGAAGATGACATCCGGAATGTCATAGGAAGGTGCAAGGACACTCTCTCCACAATCACGGGGCCGACCACCCAGAACACAT
ATGGGCGGAATGAAGGGGCCTGGATGAAGGACCCCCTGGCCAAGGATGAGCGGATTTACGTAACCAACTATTACTACGGCAACACCCTGG
TAGAGTTCCGGAACCTGGAGAACTTCAAACAAGGTCGCTGGAGCAATTCCTACAAGCTCCCGTACAGCTGGATCGGCACAGGCCACGTGG
TATACAATGGCGCCTTCTACTACAATCGCGCCTTCACCCGCAACATCATCAAGTACGACCTGAAGCAGCGCTACGTGGCTGCCTGGGCCA
TGCTGCATGACGTGGCCTACGAGGAGGCCACCCCCTGGCGATGGCAGGGCCACTCAGACGTGGACTTTGCTGTGGACGAGAATGGCCTAT
GGCTCATCTACCCGGCCCTGGACGATGAGGGCTTCAGCCAGGAGGTCATTGTCCTGAGCAAGCTCAATGCCGCGGACCTGAGCACACAGA
AGGAGACCACATGGCGCACGGGGCTCCGGAGGAATTTCTACGGCAACTGCTTCGTCATCTGTGGGGTGCTGTATGCCGTGGATAGCTACA
ACCAGCGGAATGCCAACATCTCCTACGCTTTCGACACCCACACCAACACACAGATCGTCCCCAGGCTGCTGTTCGAGAATGAGTATTCCT
ATACGACCCAGATAGACTACAACCCCAAGGACCGCCTGCTCTATGCCTGGGACAATGGCCACCAGGTCACTTACCATGTCATCTTTGCCT
ACTGACACCCTTGTCCCCACAAGCAGAAGCACAGAGGGGTCACTAGCACCTTGTGTGTATGTGTGTGCGCGCACGTGTGTGTAGGTGGGT
ATGTGTTGTTTAAAAATATATATTATTTTGTATAATATTGCAAATGTAAAATGACAATTTGGGTCTATTTTTTTATATGGATTGTAGATC

>57258_57258_4_NARF-OLFML2B_NARF_chr17_80417948_ENST00000345415_OLFML2B_chr1_161989972_ENST00000367940_length(amino acids)=729AA_BP=36
MKCEHCTRKECSKKTKTDDQENVSADAPSPAQENGELLGDYDKVKAMSEGSDCQCKCVVRPLGRDACQRINAGASRKEDFYTVETITSGS
SCKCACVAPPSALNPCEGDFRLQKLREADSQDLKLSTIIDMLEGAFYGLDLLKLHSVTTKLVGRVDKLEEEVSKNLTKENEQIKEDMEEI
RTEMNKRGKENCSENILDSMPDIRSALQRDAAAAYAHPEQYEERFLQEETVSQQINSIELLQTRPLALPEVVKSQRPLQRQVHLRGRPAS
QPTVIRGITYYKAKVSEEENDIEEQQDEFFSGDNGVDLLIEDQLLRHNGLMTSVTRRPAATRQGHSTAVTSDLNARTAPWSSALPQPSTS
DPSIANHASVGPTLQTTSVSPDPTRESVLQPSPQVPATTVAHTATQQPAAPAPPAVSPREALMEAMHTVPVPPTTVRTDSLGKDAPAGWG
TTPASPTLSPEEEDDIRNVIGRCKDTLSTITGPTTQNTYGRNEGAWMKDPLAKDERIYVTNYYYGNTLVEFRNLENFKQGRWSNSYKLPY
SWIGTGHVVYNGAFYYNRAFTRNIIKYDLKQRYVAAWAMLHDVAYEEATPWRWQGHSDVDFAVDENGLWLIYPALDDEGFSQEVIVLSKL
NAADLSTQKETTWRTGLRRNFYGNCFVICGVLYAVDSYNQRNANISYAFDTHTNTQIVPRLLFENEYSYTTQIDYNPKDRLLYAWDNGHQ

--------------------------------------------------------------
>57258_57258_5_NARF-OLFML2B_NARF_chr17_80417948_ENST00000457415_OLFML2B_chr1_161989972_ENST00000294794_length(transcript)=2771nt_BP=209nt
GGGAGGACAACAAAGGGCCGCGGGCGGCGGGCAGTGGTGTCCCAGTCTCCCGGTGCTTCCCTGAGGCTGAGGCGCCCGGCCTCCCGCCCG
CCGCGCTCCAGATGAAGTGTGAGCACTGCACGCGCAAGGAATGTAGTAAGAAAACAAAAACTGATGACCAAGAGAATGTGTCAGCCGATG
CACCGAGTCCAGCCCAGGAAAATGGAGAGTTGCTGGGGGACTATGACAAGGTCAAGGCTATGTCTGAGGGCTCGGACTGTCAGTGCAAGT
GTGTGGTGAGACCCCTGGGCCGGGATGCCTGCCAGAGGATCAATGCGGGGGCCTCCAGGAAGGAAGACTTCTATACCGTGGAAACCATCA
CCTCAGGCTCGTCGTGCAAGTGTGCCTGTGTAGCACCCCCATCGGCCCTCAATCCCTGCGAGGGAGACTTCAGGCTCCAGAAGCTGCGGG
AGGCAGACAGCCAGGACTTGAAGCTCTCCACAATCATAGACATGTTGGAAGGAGCGTTCTATGGCCTGGATCTCCTGAAGCTACATTCAG
TCACCACCAAACTGGTGGGGCGAGTGGATAAACTGGAGGAGGAAGTGTCTAAAAACCTCACCAAGGAAAATGAACAAATCAAAGAGGACA
TGGAAGAAATTCGAACCGAGATGAATAAGCGAGGCAAAGAAAATTGCTCTGAAAACATCCTAGATAGCATGCCAGACATCCGCTCAGCCC
TGCAGAGGGATGCAGCAGCAGCCTACGCCCACCCAGAGTATGAAGAGCGGTTTCTGCAGGAAGAAACCGTGTCCCAGCAGATCAACTCCA
TCGAACTTCTGCAGACGCGACCCCTGGCTCTGCCTGAGGTGGTGAAGTCACAGCGGCCCCTGCAGAGGCAGGTCCACCTGAGAGGCCGGC
CGGCCTCCCAGCCCACTGTCATCCGGGGCATCACCTACTATAAAGCCAAGGTCTCTGAAGAAGAGAATGACATTGAAGAGCAGCAAGATG
AGTTTTTCAGCGGTGACAATGGAGTGGATTTGCTGATTGAAGATCAGCTCCTGAGACACAACGGCCTGATGACCAGTGTCACCCGGAGGC
CTGCAGCCACCCGTCAGGGACACAGCACTGCTGTGACAAGCGACCTGAACGCTCGGACCGCACCCTGGTCCTCAGCACTGCCACAGCCCT
CGACCTCAGATCCCAGCATCGCCAACCATGCCTCAGTGGGACCAACACTCCAAACAACCTCGGTGTCTCCAGATCCCACAAGGGAGTCAG
TCCTGCAGCCTTCTCCTCAGGTACCAGCCACCACTGTGGCCCACACAGCCACCCAGCAACCAGCAGCCCCAGCTCCTCCGGCAGTGTCTC
CCAGGGAGGCATTGATGGAAGCTATGCACACAGTCCCAGTGCCTCCCACCACAGTCAGAACAGACTCGCTGGGGAAAGATGCTCCTGCTG
GGTGGGGAACAACCCCTGCCAGCCCCACGCTGAGCCCCGAAGAAGAAGATGACATCCGGAATGTCATAGGAAGGTGCAAGGACACTCTCT
CCACAATCACGGGGCCGACCACCCAGAACACATATGGGCGGAATGAAGGGGCCTGGATGAAGGACCCCCTGGCCAAGGATGAGCGGATTT
ACGTAACCAACTATTACTACGGCAACACCCTGGTAGAGTTCCGGAACCTGGAGAACTTCAAACAAGGTCGCTGGAGCAATTCCTACAAGC
TCCCGTACAGCTGGATCGGCACAGGCCACGTGGTATACAATGGCGCCTTCTACTACAATCGCGCCTTCACCCGCAACATCATCAAGTACG
ACCTGAAGCAGCGCTACGTGGCTGCCTGGGCCATGCTGCATGACGTGGCCTACGAGGAGGCCACCCCCTGGCGATGGCAGGGCCACTCAG
ACGTGGACTTTGCTGTGGACGAGAATGGCCTATGGCTCATCTACCCGGCCCTGGACGATGAGGGCTTCAGCCAGGAGGTCATTGTCCTGA
GCAAGCTCAATGCCGCGGACCTGAGCACACAGAAGGAGACCACATGGCGCACGGGGCTCCGGAGGAATTTCTACGGCAACTGCTTCGTCA
TCTGTGGGGTGCTGTATGCCGTGGATAGCTACAACCAGCGGAATGCCAACATCTCCTACGCTTTCGACACCCACACCAACACACAGATCG
TCCCCAGGCTGCTGTTCGAGAATGAGTATTCCTATACGACCCAGATAGACTACAACCCCAAGGACCGCCTGCTCTATGCCTGGGACAATG
GCCACCAGGTCACTTACCATGTCATCTTTGCCTACTGACACCCTTGTCCCCACAAGCAGAAGCACAGAGGGGTCACTAGCACCTTGTGTG
TATGTGTGTGCGCGCACGTGTGTGTAGGTGGGTATGTGTTGTTTAAAAATATATATTATTTTGTATAATATTGCAAATGTAAAATGACAA
TTTGGGTCTATTTTTTTATATGGATTGTAGATCAATCCATACGTGTATGTGCTGGTCTCATCCTCCCCAGTTTATATTTTTGTGCAAATG
AACTTCTCCTTTTGACCAGTAACCACCTTCCTTCAAGCCTTCAGCCCCTCCAGCTCCAAGTCTCAGATCTCGACCATTGAAAAGGTTTCT
TCATCTGGGTCTTGCAGGAGGCAGGCAACACCAGGAGCAGAAATGAAAGAGGCAAGAAAGAAGTGCTATGTGGCGAGAAAAAAAGTTTTA

>57258_57258_5_NARF-OLFML2B_NARF_chr17_80417948_ENST00000457415_OLFML2B_chr1_161989972_ENST00000294794_length(amino acids)=728AA_BP=36
MKCEHCTRKECSKKTKTDDQENVSADAPSPAQENGELLGDYDKVKAMSEGSDCQCKCVVRPLGRDACQRINAGASRKEDFYTVETITSGS
SCKCACVAPPSALNPCEGDFRLQKLREADSQDLKLSTIIDMLEGAFYGLDLLKLHSVTTKLVGRVDKLEEEVSKNLTKENEQIKEDMEEI
RTEMNKRGKENCSENILDSMPDIRSALQRDAAAAYAHPEYEERFLQEETVSQQINSIELLQTRPLALPEVVKSQRPLQRQVHLRGRPASQ
PTVIRGITYYKAKVSEEENDIEEQQDEFFSGDNGVDLLIEDQLLRHNGLMTSVTRRPAATRQGHSTAVTSDLNARTAPWSSALPQPSTSD
PSIANHASVGPTLQTTSVSPDPTRESVLQPSPQVPATTVAHTATQQPAAPAPPAVSPREALMEAMHTVPVPPTTVRTDSLGKDAPAGWGT
TPASPTLSPEEEDDIRNVIGRCKDTLSTITGPTTQNTYGRNEGAWMKDPLAKDERIYVTNYYYGNTLVEFRNLENFKQGRWSNSYKLPYS
WIGTGHVVYNGAFYYNRAFTRNIIKYDLKQRYVAAWAMLHDVAYEEATPWRWQGHSDVDFAVDENGLWLIYPALDDEGFSQEVIVLSKLN
AADLSTQKETTWRTGLRRNFYGNCFVICGVLYAVDSYNQRNANISYAFDTHTNTQIVPRLLFENEYSYTTQIDYNPKDRLLYAWDNGHQV

--------------------------------------------------------------
>57258_57258_6_NARF-OLFML2B_NARF_chr17_80417948_ENST00000457415_OLFML2B_chr1_161989972_ENST00000367940_length(transcript)=2510nt_BP=209nt
GGGAGGACAACAAAGGGCCGCGGGCGGCGGGCAGTGGTGTCCCAGTCTCCCGGTGCTTCCCTGAGGCTGAGGCGCCCGGCCTCCCGCCCG
CCGCGCTCCAGATGAAGTGTGAGCACTGCACGCGCAAGGAATGTAGTAAGAAAACAAAAACTGATGACCAAGAGAATGTGTCAGCCGATG
CACCGAGTCCAGCCCAGGAAAATGGAGAGTTGCTGGGGGACTATGACAAGGTCAAGGCTATGTCTGAGGGCTCGGACTGTCAGTGCAAGT
GTGTGGTGAGACCCCTGGGCCGGGATGCCTGCCAGAGGATCAATGCGGGGGCCTCCAGGAAGGAAGACTTCTATACCGTGGAAACCATCA
CCTCAGGCTCGTCGTGCAAGTGTGCCTGTGTAGCACCCCCATCGGCCCTCAATCCCTGCGAGGGAGACTTCAGGCTCCAGAAGCTGCGGG
AGGCAGACAGCCAGGACTTGAAGCTCTCCACAATCATAGACATGTTGGAAGGAGCGTTCTATGGCCTGGATCTCCTGAAGCTACATTCAG
TCACCACCAAACTGGTGGGGCGAGTGGATAAACTGGAGGAGGAAGTGTCTAAAAACCTCACCAAGGAAAATGAACAAATCAAAGAGGACA
TGGAAGAAATTCGAACCGAGATGAATAAGCGAGGCAAAGAAAATTGCTCTGAAAACATCCTAGATAGCATGCCAGACATCCGCTCAGCCC
TGCAGAGGGATGCAGCAGCAGCCTACGCCCACCCAGAGCAGTATGAAGAGCGGTTTCTGCAGGAAGAAACCGTGTCCCAGCAGATCAACT
CCATCGAACTTCTGCAGACGCGACCCCTGGCTCTGCCTGAGGTGGTGAAGTCACAGCGGCCCCTGCAGAGGCAGGTCCACCTGAGAGGCC
GGCCGGCCTCCCAGCCCACTGTCATCCGGGGCATCACCTACTATAAAGCCAAGGTCTCTGAAGAAGAGAATGACATTGAAGAGCAGCAAG
ATGAGTTTTTCAGCGGTGACAATGGAGTGGATTTGCTGATTGAAGATCAGCTCCTGAGACACAACGGCCTGATGACCAGTGTCACCCGGA
GGCCTGCAGCCACCCGTCAGGGACACAGCACTGCTGTGACAAGCGACCTGAACGCTCGGACCGCACCCTGGTCCTCAGCACTGCCACAGC
CCTCGACCTCAGATCCCAGCATCGCCAACCATGCCTCAGTGGGACCAACACTCCAAACAACCTCGGTGTCTCCAGATCCCACAAGGGAGT
CAGTCCTGCAGCCTTCTCCTCAGGTACCAGCCACCACTGTGGCCCACACAGCCACCCAGCAACCAGCAGCCCCAGCTCCTCCGGCAGTGT
CTCCCAGGGAGGCATTGATGGAAGCTATGCACACAGTCCCAGTGCCTCCCACCACAGTCAGAACAGACTCGCTGGGGAAAGATGCTCCTG
CTGGGTGGGGAACAACCCCTGCCAGCCCCACGCTGAGCCCCGAAGAAGAAGATGACATCCGGAATGTCATAGGAAGGTGCAAGGACACTC
TCTCCACAATCACGGGGCCGACCACCCAGAACACATATGGGCGGAATGAAGGGGCCTGGATGAAGGACCCCCTGGCCAAGGATGAGCGGA
TTTACGTAACCAACTATTACTACGGCAACACCCTGGTAGAGTTCCGGAACCTGGAGAACTTCAAACAAGGTCGCTGGAGCAATTCCTACA
AGCTCCCGTACAGCTGGATCGGCACAGGCCACGTGGTATACAATGGCGCCTTCTACTACAATCGCGCCTTCACCCGCAACATCATCAAGT
ACGACCTGAAGCAGCGCTACGTGGCTGCCTGGGCCATGCTGCATGACGTGGCCTACGAGGAGGCCACCCCCTGGCGATGGCAGGGCCACT
CAGACGTGGACTTTGCTGTGGACGAGAATGGCCTATGGCTCATCTACCCGGCCCTGGACGATGAGGGCTTCAGCCAGGAGGTCATTGTCC
TGAGCAAGCTCAATGCCGCGGACCTGAGCACACAGAAGGAGACCACATGGCGCACGGGGCTCCGGAGGAATTTCTACGGCAACTGCTTCG
TCATCTGTGGGGTGCTGTATGCCGTGGATAGCTACAACCAGCGGAATGCCAACATCTCCTACGCTTTCGACACCCACACCAACACACAGA
TCGTCCCCAGGCTGCTGTTCGAGAATGAGTATTCCTATACGACCCAGATAGACTACAACCCCAAGGACCGCCTGCTCTATGCCTGGGACA
ATGGCCACCAGGTCACTTACCATGTCATCTTTGCCTACTGACACCCTTGTCCCCACAAGCAGAAGCACAGAGGGGTCACTAGCACCTTGT
GTGTATGTGTGTGCGCGCACGTGTGTGTAGGTGGGTATGTGTTGTTTAAAAATATATATTATTTTGTATAATATTGCAAATGTAAAATGA

>57258_57258_6_NARF-OLFML2B_NARF_chr17_80417948_ENST00000457415_OLFML2B_chr1_161989972_ENST00000367940_length(amino acids)=729AA_BP=36
MKCEHCTRKECSKKTKTDDQENVSADAPSPAQENGELLGDYDKVKAMSEGSDCQCKCVVRPLGRDACQRINAGASRKEDFYTVETITSGS
SCKCACVAPPSALNPCEGDFRLQKLREADSQDLKLSTIIDMLEGAFYGLDLLKLHSVTTKLVGRVDKLEEEVSKNLTKENEQIKEDMEEI
RTEMNKRGKENCSENILDSMPDIRSALQRDAAAAYAHPEQYEERFLQEETVSQQINSIELLQTRPLALPEVVKSQRPLQRQVHLRGRPAS
QPTVIRGITYYKAKVSEEENDIEEQQDEFFSGDNGVDLLIEDQLLRHNGLMTSVTRRPAATRQGHSTAVTSDLNARTAPWSSALPQPSTS
DPSIANHASVGPTLQTTSVSPDPTRESVLQPSPQVPATTVAHTATQQPAAPAPPAVSPREALMEAMHTVPVPPTTVRTDSLGKDAPAGWG
TTPASPTLSPEEEDDIRNVIGRCKDTLSTITGPTTQNTYGRNEGAWMKDPLAKDERIYVTNYYYGNTLVEFRNLENFKQGRWSNSYKLPY
SWIGTGHVVYNGAFYYNRAFTRNIIKYDLKQRYVAAWAMLHDVAYEEATPWRWQGHSDVDFAVDENGLWLIYPALDDEGFSQEVIVLSKL
NAADLSTQKETTWRTGLRRNFYGNCFVICGVLYAVDSYNQRNANISYAFDTHTNTQIVPRLLFENEYSYTTQIDYNPKDRLLYAWDNGHQ

--------------------------------------------------------------

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Fusion Gene PPI Analysis for NARF-OLFML2B


check button Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in

ChiPPI page.


check button Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160)
HgeneHgene's interactorsTgeneTgene's interactors


check button - Retained PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenStill interaction with


check button - Lost PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


check button - Retained PPIs, but lost function due to frame-shift fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


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Related Drugs for NARF-OLFML2B


check button Drugs targeting genes involved in this fusion gene.
(DrugBank Version 5.1.8 2021-05-08)
PartnerGeneUniProtAccDrugBank IDDrug nameDrug activityDrug typeDrug status

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Related Diseases for NARF-OLFML2B


check button Diseases associated with fusion partners.
(DisGeNet 4.0)
PartnerGeneDisease IDDisease name# pubmedsSource