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Center for Computational Systems Medicine
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Fusion Gene Summary

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Fusion Gene ORF analysis

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Fusion Genomic Features

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Fusion Protein Features

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Fusion Gene Sequence

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Fusion Gene PPI analysis

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Related Drugs

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Related Diseases

Fusion gene:NBEA-NDFIP2 (FusionGDB2 ID:57426)

Fusion Gene Summary for NBEA-NDFIP2

check button Fusion gene summary
Fusion gene informationFusion gene name: NBEA-NDFIP2
Fusion gene ID: 57426
HgeneTgene
Gene symbol

NBEA

NDFIP2

Gene ID

26960

54602

Gene nameneurobeachinNedd4 family interacting protein 2
SynonymsBCL8B|LYST2N4WBP5A
Cytomap

13q13.3

13q31.1

Type of geneprotein-codingprotein-coding
Descriptionneurobeachinlysosomal-trafficking regulator 2NEDD4 family-interacting protein 2MAPK-activating protein PM04 PM05 PM06 PM07NEDD4 WW domain-binding protein 5ANF-kappa-B-activating protein 413putative MAPK-activating protein PM04/PM05/PM06/PM07putative NF-kappa-B-activating protein 413
Modification date2020032820200313
UniProtAcc

Q8NFP9

Q9NV92

Ensembl transtripts involved in fusion geneENST00000310336, ENST00000379939, 
ENST00000400445, ENST00000540320, 
ENST00000379922, ENST00000461581, 
ENST00000537702, 		ENST00000494647, 
ENST00000218652, 
Fusion gene scores* DoF score15 X 15 X 7=15754 X 2 X 4=32
# samples 154
** MAII scorelog2(15/1575*10)=-3.39231742277876
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0		log2(4/32*10)=0.321928094887362
effective Gene in Pan-Cancer Fusion Genes (eGinPCFGs).
DoF>8 and MAII>0
Context

PubMed: NBEA [Title/Abstract] AND NDFIP2 [Title/Abstract] AND fusion [Title/Abstract]

Most frequent breakpointNBEA(35517251)-NDFIP2(80094945), # samples:1
Anticipated loss of major functional domain due to fusion event.
* DoF score (Degree of Frequency) = # partners X # break points X # cancer types
** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)

check button Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez
PartnerGeneGO IDGO termPubMed ID

check buttonFusion gene breakpoints across NBEA (5'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check buttonFusion gene breakpoints across NDFIP2 (3'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check button Fusion gene information from two resources (ChiTars 5.0 and ChimerDB 4.0)
* All genome coordinats were lifted-over on hg19.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
SourceDiseaseSampleHgeneHchrHbpHstrandTgeneTchrTbpTstrand
ChimerDB4LUADTCGA-50-6591-01ANBEAchr13

35517251

-NDFIP2chr13

80094945

+


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Fusion Gene ORF analysis for NBEA-NDFIP2

check button Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
ORFHenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrand
5CDS-3UTRENST00000310336ENST00000494647NBEAchr13

35517251

-NDFIP2chr13

80094945

+
5CDS-3UTRENST00000379939ENST00000494647NBEAchr13

35517251

-NDFIP2chr13

80094945

+
5CDS-3UTRENST00000400445ENST00000494647NBEAchr13

35517251

-NDFIP2chr13

80094945

+
5CDS-3UTRENST00000540320ENST00000494647NBEAchr13

35517251

-NDFIP2chr13

80094945

+
In-frameENST00000310336ENST00000218652NBEAchr13

35517251

-NDFIP2chr13

80094945

+
In-frameENST00000379939ENST00000218652NBEAchr13

35517251

-NDFIP2chr13

80094945

+
In-frameENST00000400445ENST00000218652NBEAchr13

35517251

-NDFIP2chr13

80094945

+
In-frameENST00000540320ENST00000218652NBEAchr13

35517251

-NDFIP2chr13

80094945

+
intron-3CDSENST00000379922ENST00000218652NBEAchr13

35517251

-NDFIP2chr13

80094945

+
intron-3CDSENST00000461581ENST00000218652NBEAchr13

35517251

-NDFIP2chr13

80094945

+
intron-3CDSENST00000537702ENST00000218652NBEAchr13

35517251

-NDFIP2chr13

80094945

+
intron-3UTRENST00000379922ENST00000494647NBEAchr13

35517251

-NDFIP2chr13

80094945

+
intron-3UTRENST00000461581ENST00000494647NBEAchr13

35517251

-NDFIP2chr13

80094945

+
intron-3UTRENST00000537702ENST00000494647NBEAchr13

35517251

-NDFIP2chr13

80094945

+

check buttonORFfinder result based on the fusion transcript sequence of in-frame fusion genes.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandSeq length
(transcript)		BP loci
(transcript)		Predicted start
(transcript)		Predicted stop
(transcript)		Seq length
(amino acids)
ENST00000540320NBEAchr1335517251-ENST00000218652NDFIP2chr1380094945+50808284201517365
ENST00000400445NBEAchr1335517251-ENST00000218652NDFIP2chr1380094945+50808284201517365
ENST00000310336NBEAchr1335517251-ENST00000218652NDFIP2chr1380094945+4752500921189365
ENST00000379939NBEAchr1335517251-ENST00000218652NDFIP2chr1380094945+4707455471144365

check buttonDeepORF prediction of the coding potential based on the fusion transcript sequence of in-frame fusion genes. DeepORF is a coding potential classifier based on convolutional neural network by comparing the real Ribo-seq data. If the no-coding score < 0.5 and coding score > 0.5, then the in-frame fusion transcript is predicted as being likely translated.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandNo-coding scoreCoding score
ENST00000540320ENST00000218652NBEAchr1335517251-NDFIP2chr1380094945+0.0001914490.9998086
ENST00000400445ENST00000218652NBEAchr1335517251-NDFIP2chr1380094945+0.0001914490.9998086
ENST00000310336ENST00000218652NBEAchr1335517251-NDFIP2chr1380094945+0.0001505810.99984944
ENST00000379939ENST00000218652NBEAchr1335517251-NDFIP2chr1380094945+0.0001462250.99985373

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Fusion Genomic Features for NBEA-NDFIP2


check buttonFusionAI prediction of the potential fusion gene breakpoint based on the pre-mature RNA sequence context (+/- 5kb of individual partner genes, total 20kb length sequence). FusionAI is a fusion gene breakpoint classifier based on convolutional neural network by comparing the fusion positive and negative sequence context of ~ 20K fusion gene data. From here, we can have the relative potentency of the 20K genomic sequence how individual sequnce will be likely used as the gene fusion breakpoints.
HgeneHchrHbpHstrandTgeneTchrTbpTstrand1-pp (fusion gene breakpoint)

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions. We integrated a total of 44 different types of human genomic feature loci information across five big categories including virus integration sites, repeats, structural variants, chromatin states, and gene expression regulation. More details are in help page.
genomic feature

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions that are ovelapped with the top 1% feature importance score regions. More details are in help page.

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Fusion Protein Features for NBEA-NDFIP2


check button Four levels of functional features of fusion genes
Go to FGviewer search page for the most frequent breakpoint (https://ccsmweb.uth.edu/FGviewer/chr13:35517251/chr13:80094945)
- FGviewer provides the online visualization of the retention search of the protein functional features across DNA, RNA, protein, and pathological levels.
- How to search
1. Put your fusion gene symbol.
2. Press the tab key until there will be shown the breakpoint information filled.
4. Go down and press 'Search' tab twice.
4. Go down to have the hyperlink of the search result.
5. Click the hyperlink.
6. See the FGviewer result for your fusion gene.
FGviewer

check buttonMain function of each fusion partner protein. (from UniProt)
HgeneTgene
NBEA

Q8NFP9

NDFIP2

Q9NV92

FUNCTION: Binds to type II regulatory subunits of protein kinase A and anchors/targets them to the membrane. May anchor the kinase to cytoskeletal and/or organelle-associated proteins (By similarity). {ECO:0000250}.FUNCTION: Activates HECT domain-containing E3 ubiquitin-protein ligases, including ITCH, NEDD4, NEDD4L, SMURF2, WWP1 and WWP2, and consequently modulates the stability of their targets. As a result, may control many cellular processes. Recruits ITCH, NEDD4 and SMURF2 to endosomal membranes. Negatively regulates KCNH2 potassium channel activity by decreasing its cell-surface expression and interfering with channel maturation through recruitment of NEDD4L to the Golgi apparatus and multivesicular body where it mediates KCNH2 degradation (PubMed:26363003). May modulate EGFR signaling. Together with NDFIP1, limits the cytokine signaling and expansion of effector Th2 T-cells by promoting degradation of JAK1, probably by ITCH- and NEDD4L-mediated ubiquitination (By similarity). {ECO:0000250|UniProtKB:Q91ZP6, ECO:0000269|PubMed:12761501, ECO:0000269|PubMed:19343052, ECO:0000269|PubMed:20534535, ECO:0000269|PubMed:26363003}.

check buttonRetention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at

download page


* Minus value of BPloci means that the break pointn is located before the CDS.
- In-frame and retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
TgeneNDFIP2chr13:35517251chr13:80094945ENST0000021865208148_1511071399.3333333333333MotifNote=PPxY motif 1
TgeneNDFIP2chr13:35517251chr13:80094945ENST0000021865208174_1771071399.3333333333333MotifNote=PPxY motif 2
TgeneNDFIP2chr13:35517251chr13:80094945ENST0000021865208184_1861071399.3333333333333MotifNote=PPxY motif 3
TgeneNDFIP2chr13:35517251chr13:80094945ENST0000021865208253_2571071399.3333333333333Topological domainExtracellular
TgeneNDFIP2chr13:35517251chr13:80094945ENST0000021865208279_2871071399.3333333333333Topological domainCytoplasmic
TgeneNDFIP2chr13:35517251chr13:80094945ENST0000021865208309_3361071399.3333333333333Topological domainExtracellular
TgeneNDFIP2chr13:35517251chr13:80094945ENST0000021865208232_2521071399.3333333333333TransmembraneHelical
TgeneNDFIP2chr13:35517251chr13:80094945ENST0000021865208258_2781071399.3333333333333TransmembraneHelical
TgeneNDFIP2chr13:35517251chr13:80094945ENST0000021865208288_3081071399.3333333333333TransmembraneHelical

- In-frame and not-retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneNBEAchr13:35517251chr13:80094945ENST00000379922-1132147_22550525.0DomainBEACH-type PH
HgeneNBEAchr13:35517251chr13:80094945ENST00000379922-1132274_25630525.0DomainBEACH
HgeneNBEAchr13:35517251chr13:80094945ENST00000400445-1582147_2255982947.0DomainBEACH-type PH
HgeneNBEAchr13:35517251chr13:80094945ENST00000400445-1582274_2563982947.0DomainBEACH
HgeneNBEAchr13:35517251chr13:80094945ENST00000537702-1182147_22550740.0DomainBEACH-type PH
HgeneNBEAchr13:35517251chr13:80094945ENST00000537702-1182274_25630740.0DomainBEACH
HgeneNBEAchr13:35517251chr13:80094945ENST00000379922-1131326_13680525.0RepeatWD 1
HgeneNBEAchr13:35517251chr13:80094945ENST00000379922-1132718_27610525.0RepeatWD 2
HgeneNBEAchr13:35517251chr13:80094945ENST00000379922-1132778_28180525.0RepeatWD 3
HgeneNBEAchr13:35517251chr13:80094945ENST00000379922-1132860_28990525.0RepeatWD 4
HgeneNBEAchr13:35517251chr13:80094945ENST00000379922-1132902_29410525.0RepeatWD 5
HgeneNBEAchr13:35517251chr13:80094945ENST00000400445-1581326_1368982947.0RepeatWD 1
HgeneNBEAchr13:35517251chr13:80094945ENST00000400445-1582718_2761982947.0RepeatWD 2
HgeneNBEAchr13:35517251chr13:80094945ENST00000400445-1582778_2818982947.0RepeatWD 3
HgeneNBEAchr13:35517251chr13:80094945ENST00000400445-1582860_2899982947.0RepeatWD 4
HgeneNBEAchr13:35517251chr13:80094945ENST00000400445-1582902_2941982947.0RepeatWD 5
HgeneNBEAchr13:35517251chr13:80094945ENST00000537702-1181326_13680740.0RepeatWD 1
HgeneNBEAchr13:35517251chr13:80094945ENST00000537702-1182718_27610740.0RepeatWD 2
HgeneNBEAchr13:35517251chr13:80094945ENST00000537702-1182778_28180740.0RepeatWD 3
HgeneNBEAchr13:35517251chr13:80094945ENST00000537702-1182860_28990740.0RepeatWD 4
HgeneNBEAchr13:35517251chr13:80094945ENST00000537702-1182902_29410740.0RepeatWD 5
TgeneNDFIP2chr13:35517251chr13:80094945ENST00000218652081_2311071399.3333333333333Topological domainCytoplasmic


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Fusion Gene Sequence for NBEA-NDFIP2


check button For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. To have fusion amino acid sequence, we ran ORFfinder and chose the longest ORF among the all predicted ones.
>57426_57426_1_NBEA-NDFIP2_NBEA_chr13_35517251_ENST00000310336_NDFIP2_chr13_80094945_ENST00000218652_length(transcript)=4752nt_BP=500nt
GCGGCGTCGGGGCTTCACAACAACAGTGGTGGCCGTAGCAGCGGCCGGGCCGGGCTGAGGCGCAGGCGGGGAGCGGGCCCGGCGCCGCGG
CGCTGGTGGATGCTGGGGCTCCGAGGCGACGGCCGGGGGGCGGGGGCCGAGGCAGGTATAACGGTACCGGCGGCGGCAGCGCCGCTGCTC
TTCCCTTCTCCTCAGGAGGGGGGCCAATGGCTAGCGAGAAGCCGGGCCCGGGCCCGGGGCTCGAGCCTCAGCCCGTGGGGCTCATTGCCG
TCGGGGCCGCTGGCGGAGGCGGCGGGGGCAGCGGTGGTGGCGGCACCGGGGGCAGCGGGATGGGGGAGCTAAGGGGGGCGTCCGGCTCCG
GCTCGGTGATGCTCCCCGCGGGGATGATTAACCCTTCGGTGCCGATCCGCAACATCCGGATGAAATTCGCAGTGTTGATTGGACTCATAC
AGGTCGGAGAGGTCAGCAACAGGGACATCGTGGAGACGGTGCTCAACCTGCTTCTTAATGAAGAGGATAACTCAGAATCATCGGCTATAG
AGCAGCCACCTACTTCAAACCCAGCACCGCAGATTGTGCAGGCTGCGTCTTCAGCACCAGCACTTGAAACTGACTCTTCCCCTCCACCAT
ATAGTAGTATTACTGTGGAAGTACCTACAACTTCAGATACAGAAGTTTACGGTGAGTTTTATCCCGTGCCACCTCCCTATAGCGTTGCTA
CCTCTCTTCCTACATACGATGAAGCTGAGAAGGCTAAAGCTGCTGCAATGGCAGCTGCAGCAGCAGAAACATCTCAAAGAATTCAGGAGG
AAGAGTGTCCACCAAGAGATGACTTCAGTGATGCAGACCAGCTCAGAGTGGGGAATGATGGCATTTTCATGCTGGCATTTTTCATGGCAT
TTATTTTCAACTGGCTTGGATTTTGTTTATCCTTCTGTATCACCAATACCATAGCTGGAAGGTATGGTGCTATCTGCGGATTTGGCCTTT
CCTTGATCAAATGGATCCTTATTGTCAGGTTTTCTGATTATTTTACTGGATATTTCAATGGACAGTATTGGCTTTGGTGGATATTTCTTG
TACTTGGCCTGCTCCTTTTCTTCAGAGGATTTGTTAATTATCTAAAAGTCAGAAACATGTCTGAAAGTATGGCAGCTGCTCATAGAACAA
GGTATTTCTTCTTATTGTAGAGACTGCATCAACCCGACATTCCTTTCTTATACCAATGTGAAATTTCCAGATCATCTGTAAACCTACAAC
TTTAATAGAAGACTACTAATAACAGAAGACAAATTAGTGAAGAAAAGACGGAGTTTCGAAATTGAATGGCAGGGTGGTTTTTGCTTACAA
GCCATTTCTGTTCATTCTTTAAGTATCTATATTTCATTTGTTTTGCACATATGCATATGTGCCCATTTAAGATATTTGCATATACTTGAT
AGAAACCATAAAGTTGTAGCAGTTAAGTCCAGTCACATTTGGTTAATCAGTGTTTGATATAATTGAAAGAGTTGAGTGGATAAACAGTCT
TCCAGCTTGTAAATGCCATTGACTTCTGACCTGACATTTAGTATAATAAAAATGAAATTCTTAACCATGTCAAATGATTTAGTTTCTGGC
TCTTAGACTCATCTGGCAGTTCTACACATGAAACATCTTTTGTTATATAAGGTGTATTGAAACCTGCAGTGCTGATTATTAGAAAGGATT
TGTCAGATTTTTGAACATGATATTTACATTATTATTTAGGAAAACTCTTCCTGTAAATAACCATGCATAACTTACTTTCTGCAATGTTTT
CTTAGAAATTGTGTCCAGATAGCTTTCACTAATTTTAAATTAAGTGAACTAAATATATATGTGTATATGTATACACATATATATACACAC
ACACATATATATATTTAGAAACGTGAGTGTTAAAGATAGAATTTGTTTTAGGACAAATTTTAAGAAAATGTGGGAATACCAAATGTCCTT
TATAAGAAAAATAAATTTTATTTTAAGGGACATACTAGTTTTAGGGATTTTCAGATGGGAAGCTGCATTTTTAGGATTGCCCATCTTAAG
AGATCTTGCAGGAAGAGATTGTATTAGATATTATATTTATTTCATTTAAGATAATTTTCAAAGTTAATTTTCTAAATAAGATAATTCTCA
TTTGTGTTTGTCTTTTAAAAGGCCAATAAAATATCTTTCAGTATCATTGTAATAATTTTTTAGAGTTTAATTTGTAAAGCTTAGCAAATA
AAATCTTGTACTATGAATAGCTTCTTGCTTTATGACTTTAGGATTAACTTGTAAAAAACATATCCTGAACTGAGATATGCAAAATACTCA
TTTTCAAGTTATGGAAATGTGTTTGTGGCATATAGGACTGTGGGGTCTGTGTGTGTAGTGAGAGTGTGTAGCCACTATTATAACTGGAAT
TTAATTTACATTCATAAACTACTATATTTCCCATCTTGCAAATCATTTTATGTCTCATCTGTTTTTCCTTTCGGTTATATCTTTGGTTTT
GAATACCAACATTTAAAATGATGGTATTTTATCTTTTAAACTTAAAAATTATTTAATACAGCTATATGGACCTTATAAAATTGATTTCTT
ATTTATTATTAGACATTACTACTAAAAGGTACATCTAACTATTCAGGGACATTTTTCCATTTCCAAAAAATAAAATTTATTATGCTTTAT
AACCTCTTCTGTATTTTCTAATTTTTTCATTGTCTTTGATAAATAAAACAGTTTTGTTTTGCTAATATAGCCTATTTTTTGTTTTGTCTC
ATTCAGTTTACTTTCCTGCGTAGAATTTTTATTGTTATATTAAAATTTTTATTGTTGTATTAAAGTACCTGTGTTACACCCCTTGAAGTA
AGACAGTAGCATGGGGTAAAGAAAAAATATTTAGTTTAGTTGCCTAATTTGGAAGTTAATTAAAATTAAACTGTACTAATAACATATTCA
AACTCATGCTGGATCTCTTTCATATTAATTTCTTATAGACCTGTACTTTATTCTTTCAATAATTTTTAAATGAAATTAAGCTTTGCTACA
TGGTAATTAAATAATTACTAGGAAGCTTAGCTATCAAACATCGACTTACTAAAATTTCATTTTAGCTTTTATGGTATATGTGCTTGTTTT
CTGAATATGGATACATGTTACTTTTGATCCAGCATCAAAACTTCACTTTTTGTTTTGACTTTTCCCCCCAAATCTGTAAGGTTCAAGTAT
ACATATTACTGAATCCTCTATAATTGGCATAATTCAATGGTAGCCTTAAATCTCATCATGTAAGCAGGGGAATCAGAATGTTATTTTCAA
GAACTTAATGTTCCCTTCAGATATATAAAATCCTGCATACTTCATTTCCTGTGAGCTTGAACAGCTGCTGTTGTGTTTTGGGGATGCTTG
ATCATCTTTGCACTCTGCCTTAAAGATTGAAAAATCAAAACTCTTGTTAGGGTATCTAAACATTTTTGAGTGTGAACTGGGGATTGGAAG
TTAATACAAAAAAATTTCAAATTATTTCTATTGTAAATGAATAAGCTAGTCATGGCTAGGATAATCCATTTTCATGTATTTATGCAATAA
ACTGAATTTTAAGGCAAAAACAACACTTTTCTATATAGTGTATGCAGGACAGATTTTAGAAACTTAGATTAAAATACAAATCCCATTACA
TTTGGTTAAAATGAAAATCTCTGCTTAATGGAAAAAATACTAATCTTTAGCCTATTTTGAGTCTATAAGATATATTTCATTTTAGACATG
CCTTCTAAGTTGTTCACAGATTTTTACCTGCTAAAACAATATTATTTCCAGTAAAACCTCTCCTAACAGGAAAAGTGGAGTTCAAAATAT
CCAATTGGAGAAAAATTCAGAGTTCCTTCATTAAATATAATTTTTTTCATCTAGTATGTACTATTTCAAGAAGTGCAAAAAGTAATGATA
GTGAATGTGATACCATACTTAACTAAGGTAATATATATCCTTAGTTTGCTCAAAAGAGTCCTGGTTATTCCTGTTTTCTCAGCTTAATAG
TGCCTCATCGTACTCTCAAAAGTGTTCTAATTTGGAGGATAAGTTATATGATCATCCTGTGTATAATTGTAGACTGTACCAAGAAGCAAC
TACCTTAGCTCCACTGCCCTTTGAGGGATGGAACTGGGGTAAGGGCAGGAGCCAGTTATTATTGCCACAGTGTTTTCTAATGAACCATTT
GGCCTGTAGAAGAGGAATAGTATTTTTTTTAATAGTTGTATTTGAATGATTCCAGCTTATCGTAAATACTAAACTGAATGGCTTTTATAT
TTTTAACTGCTGTTAAATGTTATTTTAGCATTTATTAGTTGTTTATTATTTAATTCTTCAAATAGTCATATGAAAACATATATTTGATAA
AGGTCAATTGTTAGATGATAATGTGCCATTCATTATCATAGGAATGTCCTTGCCCATATATAAAACATGCTGGCATGTATTTTACTTGTT
AATAAAGTTGTATAGATGTGGAAGTGTGAACCTGTGATGCATCCTTTTCAAAATCAGTTTAAGATTCGCATATTATCATGACTGTGACCT
CACTAAACTGTTTATGTGACAAACCTTTCAAGATTGGAGATGAAAACAACACTTGTGAAATTAGGTTGGGGTTGCAACATCTTTTAACTT

>57426_57426_1_NBEA-NDFIP2_NBEA_chr13_35517251_ENST00000310336_NDFIP2_chr13_80094945_ENST00000218652_length(amino acids)=365AA_BP=136
MVDAGAPRRRPGGGGRGRYNGTGGGSAAALPFSSGGGPMASEKPGPGPGLEPQPVGLIAVGAAGGGGGGSGGGGTGGSGMGELRGASGSG
SVMLPAGMINPSVPIRNIRMKFAVLIGLIQVGEVSNRDIVETVLNLLLNEEDNSESSAIEQPPTSNPAPQIVQAASSAPALETDSSPPPY
SSITVEVPTTSDTEVYGEFYPVPPPYSVATSLPTYDEAEKAKAAAMAAAAAETSQRIQEEECPPRDDFSDADQLRVGNDGIFMLAFFMAF
IFNWLGFCLSFCITNTIAGRYGAICGFGLSLIKWILIVRFSDYFTGYFNGQYWLWWIFLVLGLLLFFRGFVNYLKVRNMSESMAAAHRTR

--------------------------------------------------------------
>57426_57426_2_NBEA-NDFIP2_NBEA_chr13_35517251_ENST00000379939_NDFIP2_chr13_80094945_ENST00000218652_length(transcript)=4707nt_BP=455nt
CGGGCCGGGCTGAGGCGCAGGCGGGGAGCGGGCCCGGCGCCGCGGCGCTGGTGGATGCTGGGGCTCCGAGGCGACGGCCGGGGGGCGGGG
GCCGAGGCAGGTATAACGGTACCGGCGGCGGCAGCGCCGCTGCTCTTCCCTTCTCCTCAGGAGGGGGGCCAATGGCTAGCGAGAAGCCGG
GCCCGGGCCCGGGGCTCGAGCCTCAGCCCGTGGGGCTCATTGCCGTCGGGGCCGCTGGCGGAGGCGGCGGGGGCAGCGGTGGTGGCGGCA
CCGGGGGCAGCGGGATGGGGGAGCTAAGGGGGGCGTCCGGCTCCGGCTCGGTGATGCTCCCCGCGGGGATGATTAACCCTTCGGTGCCGA
TCCGCAACATCCGGATGAAATTCGCAGTGTTGATTGGACTCATACAGGTCGGAGAGGTCAGCAACAGGGACATCGTGGAGACGGTGCTCA
ACCTGCTTCTTAATGAAGAGGATAACTCAGAATCATCGGCTATAGAGCAGCCACCTACTTCAAACCCAGCACCGCAGATTGTGCAGGCTG
CGTCTTCAGCACCAGCACTTGAAACTGACTCTTCCCCTCCACCATATAGTAGTATTACTGTGGAAGTACCTACAACTTCAGATACAGAAG
TTTACGGTGAGTTTTATCCCGTGCCACCTCCCTATAGCGTTGCTACCTCTCTTCCTACATACGATGAAGCTGAGAAGGCTAAAGCTGCTG
CAATGGCAGCTGCAGCAGCAGAAACATCTCAAAGAATTCAGGAGGAAGAGTGTCCACCAAGAGATGACTTCAGTGATGCAGACCAGCTCA
GAGTGGGGAATGATGGCATTTTCATGCTGGCATTTTTCATGGCATTTATTTTCAACTGGCTTGGATTTTGTTTATCCTTCTGTATCACCA
ATACCATAGCTGGAAGGTATGGTGCTATCTGCGGATTTGGCCTTTCCTTGATCAAATGGATCCTTATTGTCAGGTTTTCTGATTATTTTA
CTGGATATTTCAATGGACAGTATTGGCTTTGGTGGATATTTCTTGTACTTGGCCTGCTCCTTTTCTTCAGAGGATTTGTTAATTATCTAA
AAGTCAGAAACATGTCTGAAAGTATGGCAGCTGCTCATAGAACAAGGTATTTCTTCTTATTGTAGAGACTGCATCAACCCGACATTCCTT
TCTTATACCAATGTGAAATTTCCAGATCATCTGTAAACCTACAACTTTAATAGAAGACTACTAATAACAGAAGACAAATTAGTGAAGAAA
AGACGGAGTTTCGAAATTGAATGGCAGGGTGGTTTTTGCTTACAAGCCATTTCTGTTCATTCTTTAAGTATCTATATTTCATTTGTTTTG
CACATATGCATATGTGCCCATTTAAGATATTTGCATATACTTGATAGAAACCATAAAGTTGTAGCAGTTAAGTCCAGTCACATTTGGTTA
ATCAGTGTTTGATATAATTGAAAGAGTTGAGTGGATAAACAGTCTTCCAGCTTGTAAATGCCATTGACTTCTGACCTGACATTTAGTATA
ATAAAAATGAAATTCTTAACCATGTCAAATGATTTAGTTTCTGGCTCTTAGACTCATCTGGCAGTTCTACACATGAAACATCTTTTGTTA
TATAAGGTGTATTGAAACCTGCAGTGCTGATTATTAGAAAGGATTTGTCAGATTTTTGAACATGATATTTACATTATTATTTAGGAAAAC
TCTTCCTGTAAATAACCATGCATAACTTACTTTCTGCAATGTTTTCTTAGAAATTGTGTCCAGATAGCTTTCACTAATTTTAAATTAAGT
GAACTAAATATATATGTGTATATGTATACACATATATATACACACACACATATATATATTTAGAAACGTGAGTGTTAAAGATAGAATTTG
TTTTAGGACAAATTTTAAGAAAATGTGGGAATACCAAATGTCCTTTATAAGAAAAATAAATTTTATTTTAAGGGACATACTAGTTTTAGG
GATTTTCAGATGGGAAGCTGCATTTTTAGGATTGCCCATCTTAAGAGATCTTGCAGGAAGAGATTGTATTAGATATTATATTTATTTCAT
TTAAGATAATTTTCAAAGTTAATTTTCTAAATAAGATAATTCTCATTTGTGTTTGTCTTTTAAAAGGCCAATAAAATATCTTTCAGTATC
ATTGTAATAATTTTTTAGAGTTTAATTTGTAAAGCTTAGCAAATAAAATCTTGTACTATGAATAGCTTCTTGCTTTATGACTTTAGGATT
AACTTGTAAAAAACATATCCTGAACTGAGATATGCAAAATACTCATTTTCAAGTTATGGAAATGTGTTTGTGGCATATAGGACTGTGGGG
TCTGTGTGTGTAGTGAGAGTGTGTAGCCACTATTATAACTGGAATTTAATTTACATTCATAAACTACTATATTTCCCATCTTGCAAATCA
TTTTATGTCTCATCTGTTTTTCCTTTCGGTTATATCTTTGGTTTTGAATACCAACATTTAAAATGATGGTATTTTATCTTTTAAACTTAA
AAATTATTTAATACAGCTATATGGACCTTATAAAATTGATTTCTTATTTATTATTAGACATTACTACTAAAAGGTACATCTAACTATTCA
GGGACATTTTTCCATTTCCAAAAAATAAAATTTATTATGCTTTATAACCTCTTCTGTATTTTCTAATTTTTTCATTGTCTTTGATAAATA
AAACAGTTTTGTTTTGCTAATATAGCCTATTTTTTGTTTTGTCTCATTCAGTTTACTTTCCTGCGTAGAATTTTTATTGTTATATTAAAA
TTTTTATTGTTGTATTAAAGTACCTGTGTTACACCCCTTGAAGTAAGACAGTAGCATGGGGTAAAGAAAAAATATTTAGTTTAGTTGCCT
AATTTGGAAGTTAATTAAAATTAAACTGTACTAATAACATATTCAAACTCATGCTGGATCTCTTTCATATTAATTTCTTATAGACCTGTA
CTTTATTCTTTCAATAATTTTTAAATGAAATTAAGCTTTGCTACATGGTAATTAAATAATTACTAGGAAGCTTAGCTATCAAACATCGAC
TTACTAAAATTTCATTTTAGCTTTTATGGTATATGTGCTTGTTTTCTGAATATGGATACATGTTACTTTTGATCCAGCATCAAAACTTCA
CTTTTTGTTTTGACTTTTCCCCCCAAATCTGTAAGGTTCAAGTATACATATTACTGAATCCTCTATAATTGGCATAATTCAATGGTAGCC
TTAAATCTCATCATGTAAGCAGGGGAATCAGAATGTTATTTTCAAGAACTTAATGTTCCCTTCAGATATATAAAATCCTGCATACTTCAT
TTCCTGTGAGCTTGAACAGCTGCTGTTGTGTTTTGGGGATGCTTGATCATCTTTGCACTCTGCCTTAAAGATTGAAAAATCAAAACTCTT
GTTAGGGTATCTAAACATTTTTGAGTGTGAACTGGGGATTGGAAGTTAATACAAAAAAATTTCAAATTATTTCTATTGTAAATGAATAAG
CTAGTCATGGCTAGGATAATCCATTTTCATGTATTTATGCAATAAACTGAATTTTAAGGCAAAAACAACACTTTTCTATATAGTGTATGC
AGGACAGATTTTAGAAACTTAGATTAAAATACAAATCCCATTACATTTGGTTAAAATGAAAATCTCTGCTTAATGGAAAAAATACTAATC
TTTAGCCTATTTTGAGTCTATAAGATATATTTCATTTTAGACATGCCTTCTAAGTTGTTCACAGATTTTTACCTGCTAAAACAATATTAT
TTCCAGTAAAACCTCTCCTAACAGGAAAAGTGGAGTTCAAAATATCCAATTGGAGAAAAATTCAGAGTTCCTTCATTAAATATAATTTTT
TTCATCTAGTATGTACTATTTCAAGAAGTGCAAAAAGTAATGATAGTGAATGTGATACCATACTTAACTAAGGTAATATATATCCTTAGT
TTGCTCAAAAGAGTCCTGGTTATTCCTGTTTTCTCAGCTTAATAGTGCCTCATCGTACTCTCAAAAGTGTTCTAATTTGGAGGATAAGTT
ATATGATCATCCTGTGTATAATTGTAGACTGTACCAAGAAGCAACTACCTTAGCTCCACTGCCCTTTGAGGGATGGAACTGGGGTAAGGG
CAGGAGCCAGTTATTATTGCCACAGTGTTTTCTAATGAACCATTTGGCCTGTAGAAGAGGAATAGTATTTTTTTTAATAGTTGTATTTGA
ATGATTCCAGCTTATCGTAAATACTAAACTGAATGGCTTTTATATTTTTAACTGCTGTTAAATGTTATTTTAGCATTTATTAGTTGTTTA
TTATTTAATTCTTCAAATAGTCATATGAAAACATATATTTGATAAAGGTCAATTGTTAGATGATAATGTGCCATTCATTATCATAGGAAT
GTCCTTGCCCATATATAAAACATGCTGGCATGTATTTTACTTGTTAATAAAGTTGTATAGATGTGGAAGTGTGAACCTGTGATGCATCCT
TTTCAAAATCAGTTTAAGATTCGCATATTATCATGACTGTGACCTCACTAAACTGTTTATGTGACAAACCTTTCAAGATTGGAGATGAAA
ACAACACTTGTGAAATTAGGTTGGGGTTGCAACATCTTTTAACTTCTCAGTTATTTGTATGTCAGGAGACAGATTGTGGTTTAATTTTAA

>57426_57426_2_NBEA-NDFIP2_NBEA_chr13_35517251_ENST00000379939_NDFIP2_chr13_80094945_ENST00000218652_length(amino acids)=365AA_BP=136
MVDAGAPRRRPGGGGRGRYNGTGGGSAAALPFSSGGGPMASEKPGPGPGLEPQPVGLIAVGAAGGGGGGSGGGGTGGSGMGELRGASGSG
SVMLPAGMINPSVPIRNIRMKFAVLIGLIQVGEVSNRDIVETVLNLLLNEEDNSESSAIEQPPTSNPAPQIVQAASSAPALETDSSPPPY
SSITVEVPTTSDTEVYGEFYPVPPPYSVATSLPTYDEAEKAKAAAMAAAAAETSQRIQEEECPPRDDFSDADQLRVGNDGIFMLAFFMAF
IFNWLGFCLSFCITNTIAGRYGAICGFGLSLIKWILIVRFSDYFTGYFNGQYWLWWIFLVLGLLLFFRGFVNYLKVRNMSESMAAAHRTR

--------------------------------------------------------------
>57426_57426_3_NBEA-NDFIP2_NBEA_chr13_35517251_ENST00000400445_NDFIP2_chr13_80094945_ENST00000218652_length(transcript)=5080nt_BP=828nt
AGGCAGGGGGCGGCAACATGGCGGAGTGAGCGGCGGCGTCGGGGCTTCACAACAACAGTGGTGGCCGTAGCAGCGGCGGCAGCAGCGTCA
ATAGCATCGGCCACAGCCTGAGCTTCAGCACCGGCCAGCGTCGTGGCCAGCTGCTCGCGTCCTCGGGCTTCTCGGAGCGGCTGCAGCATC
TCCGCGGGGGGCGGGCCGGGCCGGACAGACCGGGAGAGGGAGAGAGCAGAGGCAGCGGCGGCGGCAGCGGCAGCGGCAGCGGCACACCTG
CTGGGCGGGCACAGCCGCTTGCCCGGCAGCGGTTAGCGGTACCGCCACCGCCGAGAATAAGCCTGCGGATCCCCCGCCGCCTCCGCGGGG
GAGAGCGCCGGAGCGGGCCGGGCTGAGGCGCAGGCGGGGAGCGGGCCCGGCGCCGCGGCGCTGGTGGATGCTGGGGCTCCGAGGCGACGG
CCGGGGGGCGGGGGCCGAGGCAGGTATAACGGTACCGGCGGCGGCAGCGCCGCTGCTCTTCCCTTCTCCTCAGGAGGGGGGCCAATGGCT
AGCGAGAAGCCGGGCCCGGGCCCGGGGCTCGAGCCTCAGCCCGTGGGGCTCATTGCCGTCGGGGCCGCTGGCGGAGGCGGCGGGGGCAGC
GGTGGTGGCGGCACCGGGGGCAGCGGGATGGGGGAGCTAAGGGGGGCGTCCGGCTCCGGCTCGGTGATGCTCCCCGCGGGGATGATTAAC
CCTTCGGTGCCGATCCGCAACATCCGGATGAAATTCGCAGTGTTGATTGGACTCATACAGGTCGGAGAGGTCAGCAACAGGGACATCGTG
GAGACGGTGCTCAACCTGCTTCTTAATGAAGAGGATAACTCAGAATCATCGGCTATAGAGCAGCCACCTACTTCAAACCCAGCACCGCAG
ATTGTGCAGGCTGCGTCTTCAGCACCAGCACTTGAAACTGACTCTTCCCCTCCACCATATAGTAGTATTACTGTGGAAGTACCTACAACT
TCAGATACAGAAGTTTACGGTGAGTTTTATCCCGTGCCACCTCCCTATAGCGTTGCTACCTCTCTTCCTACATACGATGAAGCTGAGAAG
GCTAAAGCTGCTGCAATGGCAGCTGCAGCAGCAGAAACATCTCAAAGAATTCAGGAGGAAGAGTGTCCACCAAGAGATGACTTCAGTGAT
GCAGACCAGCTCAGAGTGGGGAATGATGGCATTTTCATGCTGGCATTTTTCATGGCATTTATTTTCAACTGGCTTGGATTTTGTTTATCC
TTCTGTATCACCAATACCATAGCTGGAAGGTATGGTGCTATCTGCGGATTTGGCCTTTCCTTGATCAAATGGATCCTTATTGTCAGGTTT
TCTGATTATTTTACTGGATATTTCAATGGACAGTATTGGCTTTGGTGGATATTTCTTGTACTTGGCCTGCTCCTTTTCTTCAGAGGATTT
GTTAATTATCTAAAAGTCAGAAACATGTCTGAAAGTATGGCAGCTGCTCATAGAACAAGGTATTTCTTCTTATTGTAGAGACTGCATCAA
CCCGACATTCCTTTCTTATACCAATGTGAAATTTCCAGATCATCTGTAAACCTACAACTTTAATAGAAGACTACTAATAACAGAAGACAA
ATTAGTGAAGAAAAGACGGAGTTTCGAAATTGAATGGCAGGGTGGTTTTTGCTTACAAGCCATTTCTGTTCATTCTTTAAGTATCTATAT
TTCATTTGTTTTGCACATATGCATATGTGCCCATTTAAGATATTTGCATATACTTGATAGAAACCATAAAGTTGTAGCAGTTAAGTCCAG
TCACATTTGGTTAATCAGTGTTTGATATAATTGAAAGAGTTGAGTGGATAAACAGTCTTCCAGCTTGTAAATGCCATTGACTTCTGACCT
GACATTTAGTATAATAAAAATGAAATTCTTAACCATGTCAAATGATTTAGTTTCTGGCTCTTAGACTCATCTGGCAGTTCTACACATGAA
ACATCTTTTGTTATATAAGGTGTATTGAAACCTGCAGTGCTGATTATTAGAAAGGATTTGTCAGATTTTTGAACATGATATTTACATTAT
TATTTAGGAAAACTCTTCCTGTAAATAACCATGCATAACTTACTTTCTGCAATGTTTTCTTAGAAATTGTGTCCAGATAGCTTTCACTAA
TTTTAAATTAAGTGAACTAAATATATATGTGTATATGTATACACATATATATACACACACACATATATATATTTAGAAACGTGAGTGTTA
AAGATAGAATTTGTTTTAGGACAAATTTTAAGAAAATGTGGGAATACCAAATGTCCTTTATAAGAAAAATAAATTTTATTTTAAGGGACA
TACTAGTTTTAGGGATTTTCAGATGGGAAGCTGCATTTTTAGGATTGCCCATCTTAAGAGATCTTGCAGGAAGAGATTGTATTAGATATT
ATATTTATTTCATTTAAGATAATTTTCAAAGTTAATTTTCTAAATAAGATAATTCTCATTTGTGTTTGTCTTTTAAAAGGCCAATAAAAT
ATCTTTCAGTATCATTGTAATAATTTTTTAGAGTTTAATTTGTAAAGCTTAGCAAATAAAATCTTGTACTATGAATAGCTTCTTGCTTTA
TGACTTTAGGATTAACTTGTAAAAAACATATCCTGAACTGAGATATGCAAAATACTCATTTTCAAGTTATGGAAATGTGTTTGTGGCATA
TAGGACTGTGGGGTCTGTGTGTGTAGTGAGAGTGTGTAGCCACTATTATAACTGGAATTTAATTTACATTCATAAACTACTATATTTCCC
ATCTTGCAAATCATTTTATGTCTCATCTGTTTTTCCTTTCGGTTATATCTTTGGTTTTGAATACCAACATTTAAAATGATGGTATTTTAT
CTTTTAAACTTAAAAATTATTTAATACAGCTATATGGACCTTATAAAATTGATTTCTTATTTATTATTAGACATTACTACTAAAAGGTAC
ATCTAACTATTCAGGGACATTTTTCCATTTCCAAAAAATAAAATTTATTATGCTTTATAACCTCTTCTGTATTTTCTAATTTTTTCATTG
TCTTTGATAAATAAAACAGTTTTGTTTTGCTAATATAGCCTATTTTTTGTTTTGTCTCATTCAGTTTACTTTCCTGCGTAGAATTTTTAT
TGTTATATTAAAATTTTTATTGTTGTATTAAAGTACCTGTGTTACACCCCTTGAAGTAAGACAGTAGCATGGGGTAAAGAAAAAATATTT
AGTTTAGTTGCCTAATTTGGAAGTTAATTAAAATTAAACTGTACTAATAACATATTCAAACTCATGCTGGATCTCTTTCATATTAATTTC
TTATAGACCTGTACTTTATTCTTTCAATAATTTTTAAATGAAATTAAGCTTTGCTACATGGTAATTAAATAATTACTAGGAAGCTTAGCT
ATCAAACATCGACTTACTAAAATTTCATTTTAGCTTTTATGGTATATGTGCTTGTTTTCTGAATATGGATACATGTTACTTTTGATCCAG
CATCAAAACTTCACTTTTTGTTTTGACTTTTCCCCCCAAATCTGTAAGGTTCAAGTATACATATTACTGAATCCTCTATAATTGGCATAA
TTCAATGGTAGCCTTAAATCTCATCATGTAAGCAGGGGAATCAGAATGTTATTTTCAAGAACTTAATGTTCCCTTCAGATATATAAAATC
CTGCATACTTCATTTCCTGTGAGCTTGAACAGCTGCTGTTGTGTTTTGGGGATGCTTGATCATCTTTGCACTCTGCCTTAAAGATTGAAA
AATCAAAACTCTTGTTAGGGTATCTAAACATTTTTGAGTGTGAACTGGGGATTGGAAGTTAATACAAAAAAATTTCAAATTATTTCTATT
GTAAATGAATAAGCTAGTCATGGCTAGGATAATCCATTTTCATGTATTTATGCAATAAACTGAATTTTAAGGCAAAAACAACACTTTTCT
ATATAGTGTATGCAGGACAGATTTTAGAAACTTAGATTAAAATACAAATCCCATTACATTTGGTTAAAATGAAAATCTCTGCTTAATGGA
AAAAATACTAATCTTTAGCCTATTTTGAGTCTATAAGATATATTTCATTTTAGACATGCCTTCTAAGTTGTTCACAGATTTTTACCTGCT
AAAACAATATTATTTCCAGTAAAACCTCTCCTAACAGGAAAAGTGGAGTTCAAAATATCCAATTGGAGAAAAATTCAGAGTTCCTTCATT
AAATATAATTTTTTTCATCTAGTATGTACTATTTCAAGAAGTGCAAAAAGTAATGATAGTGAATGTGATACCATACTTAACTAAGGTAAT
ATATATCCTTAGTTTGCTCAAAAGAGTCCTGGTTATTCCTGTTTTCTCAGCTTAATAGTGCCTCATCGTACTCTCAAAAGTGTTCTAATT
TGGAGGATAAGTTATATGATCATCCTGTGTATAATTGTAGACTGTACCAAGAAGCAACTACCTTAGCTCCACTGCCCTTTGAGGGATGGA
ACTGGGGTAAGGGCAGGAGCCAGTTATTATTGCCACAGTGTTTTCTAATGAACCATTTGGCCTGTAGAAGAGGAATAGTATTTTTTTTAA
TAGTTGTATTTGAATGATTCCAGCTTATCGTAAATACTAAACTGAATGGCTTTTATATTTTTAACTGCTGTTAAATGTTATTTTAGCATT
TATTAGTTGTTTATTATTTAATTCTTCAAATAGTCATATGAAAACATATATTTGATAAAGGTCAATTGTTAGATGATAATGTGCCATTCA
TTATCATAGGAATGTCCTTGCCCATATATAAAACATGCTGGCATGTATTTTACTTGTTAATAAAGTTGTATAGATGTGGAAGTGTGAACC
TGTGATGCATCCTTTTCAAAATCAGTTTAAGATTCGCATATTATCATGACTGTGACCTCACTAAACTGTTTATGTGACAAACCTTTCAAG
ATTGGAGATGAAAACAACACTTGTGAAATTAGGTTGGGGTTGCAACATCTTTTAACTTCTCAGTTATTTGTATGTCAGGAGACAGATTGT

>57426_57426_3_NBEA-NDFIP2_NBEA_chr13_35517251_ENST00000400445_NDFIP2_chr13_80094945_ENST00000218652_length(amino acids)=365AA_BP=136
MVDAGAPRRRPGGGGRGRYNGTGGGSAAALPFSSGGGPMASEKPGPGPGLEPQPVGLIAVGAAGGGGGGSGGGGTGGSGMGELRGASGSG
SVMLPAGMINPSVPIRNIRMKFAVLIGLIQVGEVSNRDIVETVLNLLLNEEDNSESSAIEQPPTSNPAPQIVQAASSAPALETDSSPPPY
SSITVEVPTTSDTEVYGEFYPVPPPYSVATSLPTYDEAEKAKAAAMAAAAAETSQRIQEEECPPRDDFSDADQLRVGNDGIFMLAFFMAF
IFNWLGFCLSFCITNTIAGRYGAICGFGLSLIKWILIVRFSDYFTGYFNGQYWLWWIFLVLGLLLFFRGFVNYLKVRNMSESMAAAHRTR

--------------------------------------------------------------
>57426_57426_4_NBEA-NDFIP2_NBEA_chr13_35517251_ENST00000540320_NDFIP2_chr13_80094945_ENST00000218652_length(transcript)=5080nt_BP=828nt
AGGCAGGGGGCGGCAACATGGCGGAGTGAGCGGCGGCGTCGGGGCTTCACAACAACAGTGGTGGCCGTAGCAGCGGCGGCAGCAGCGTCA
ATAGCATCGGCCACAGCCTGAGCTTCAGCACCGGCCAGCGTCGTGGCCAGCTGCTCGCGTCCTCGGGCTTCTCGGAGCGGCTGCAGCATC
TCCGCGGGGGGCGGGCCGGGCCGGACAGACCGGGAGAGGGAGAGAGCAGAGGCAGCGGCGGCGGCAGCGGCAGCGGCAGCGGCACACCTG
CTGGGCGGGCACAGCCGCTTGCCCGGCAGCGGTTAGCGGTACCGCCACCGCCGAGAATAAGCCTGCGGATCCCCCGCCGCCTCCGCGGGG
GAGAGCGCCGGAGCGGGCCGGGCTGAGGCGCAGGCGGGGAGCGGGCCCGGCGCCGCGGCGCTGGTGGATGCTGGGGCTCCGAGGCGACGG
CCGGGGGGCGGGGGCCGAGGCAGGTATAACGGTACCGGCGGCGGCAGCGCCGCTGCTCTTCCCTTCTCCTCAGGAGGGGGGCCAATGGCT
AGCGAGAAGCCGGGCCCGGGCCCGGGGCTCGAGCCTCAGCCCGTGGGGCTCATTGCCGTCGGGGCCGCTGGCGGAGGCGGCGGGGGCAGC
GGTGGTGGCGGCACCGGGGGCAGCGGGATGGGGGAGCTAAGGGGGGCGTCCGGCTCCGGCTCGGTGATGCTCCCCGCGGGGATGATTAAC
CCTTCGGTGCCGATCCGCAACATCCGGATGAAATTCGCAGTGTTGATTGGACTCATACAGGTCGGAGAGGTCAGCAACAGGGACATCGTG
GAGACGGTGCTCAACCTGCTTCTTAATGAAGAGGATAACTCAGAATCATCGGCTATAGAGCAGCCACCTACTTCAAACCCAGCACCGCAG
ATTGTGCAGGCTGCGTCTTCAGCACCAGCACTTGAAACTGACTCTTCCCCTCCACCATATAGTAGTATTACTGTGGAAGTACCTACAACT
TCAGATACAGAAGTTTACGGTGAGTTTTATCCCGTGCCACCTCCCTATAGCGTTGCTACCTCTCTTCCTACATACGATGAAGCTGAGAAG
GCTAAAGCTGCTGCAATGGCAGCTGCAGCAGCAGAAACATCTCAAAGAATTCAGGAGGAAGAGTGTCCACCAAGAGATGACTTCAGTGAT
GCAGACCAGCTCAGAGTGGGGAATGATGGCATTTTCATGCTGGCATTTTTCATGGCATTTATTTTCAACTGGCTTGGATTTTGTTTATCC
TTCTGTATCACCAATACCATAGCTGGAAGGTATGGTGCTATCTGCGGATTTGGCCTTTCCTTGATCAAATGGATCCTTATTGTCAGGTTT
TCTGATTATTTTACTGGATATTTCAATGGACAGTATTGGCTTTGGTGGATATTTCTTGTACTTGGCCTGCTCCTTTTCTTCAGAGGATTT
GTTAATTATCTAAAAGTCAGAAACATGTCTGAAAGTATGGCAGCTGCTCATAGAACAAGGTATTTCTTCTTATTGTAGAGACTGCATCAA
CCCGACATTCCTTTCTTATACCAATGTGAAATTTCCAGATCATCTGTAAACCTACAACTTTAATAGAAGACTACTAATAACAGAAGACAA
ATTAGTGAAGAAAAGACGGAGTTTCGAAATTGAATGGCAGGGTGGTTTTTGCTTACAAGCCATTTCTGTTCATTCTTTAAGTATCTATAT
TTCATTTGTTTTGCACATATGCATATGTGCCCATTTAAGATATTTGCATATACTTGATAGAAACCATAAAGTTGTAGCAGTTAAGTCCAG
TCACATTTGGTTAATCAGTGTTTGATATAATTGAAAGAGTTGAGTGGATAAACAGTCTTCCAGCTTGTAAATGCCATTGACTTCTGACCT
GACATTTAGTATAATAAAAATGAAATTCTTAACCATGTCAAATGATTTAGTTTCTGGCTCTTAGACTCATCTGGCAGTTCTACACATGAA
ACATCTTTTGTTATATAAGGTGTATTGAAACCTGCAGTGCTGATTATTAGAAAGGATTTGTCAGATTTTTGAACATGATATTTACATTAT
TATTTAGGAAAACTCTTCCTGTAAATAACCATGCATAACTTACTTTCTGCAATGTTTTCTTAGAAATTGTGTCCAGATAGCTTTCACTAA
TTTTAAATTAAGTGAACTAAATATATATGTGTATATGTATACACATATATATACACACACACATATATATATTTAGAAACGTGAGTGTTA
AAGATAGAATTTGTTTTAGGACAAATTTTAAGAAAATGTGGGAATACCAAATGTCCTTTATAAGAAAAATAAATTTTATTTTAAGGGACA
TACTAGTTTTAGGGATTTTCAGATGGGAAGCTGCATTTTTAGGATTGCCCATCTTAAGAGATCTTGCAGGAAGAGATTGTATTAGATATT
ATATTTATTTCATTTAAGATAATTTTCAAAGTTAATTTTCTAAATAAGATAATTCTCATTTGTGTTTGTCTTTTAAAAGGCCAATAAAAT
ATCTTTCAGTATCATTGTAATAATTTTTTAGAGTTTAATTTGTAAAGCTTAGCAAATAAAATCTTGTACTATGAATAGCTTCTTGCTTTA
TGACTTTAGGATTAACTTGTAAAAAACATATCCTGAACTGAGATATGCAAAATACTCATTTTCAAGTTATGGAAATGTGTTTGTGGCATA
TAGGACTGTGGGGTCTGTGTGTGTAGTGAGAGTGTGTAGCCACTATTATAACTGGAATTTAATTTACATTCATAAACTACTATATTTCCC
ATCTTGCAAATCATTTTATGTCTCATCTGTTTTTCCTTTCGGTTATATCTTTGGTTTTGAATACCAACATTTAAAATGATGGTATTTTAT
CTTTTAAACTTAAAAATTATTTAATACAGCTATATGGACCTTATAAAATTGATTTCTTATTTATTATTAGACATTACTACTAAAAGGTAC
ATCTAACTATTCAGGGACATTTTTCCATTTCCAAAAAATAAAATTTATTATGCTTTATAACCTCTTCTGTATTTTCTAATTTTTTCATTG
TCTTTGATAAATAAAACAGTTTTGTTTTGCTAATATAGCCTATTTTTTGTTTTGTCTCATTCAGTTTACTTTCCTGCGTAGAATTTTTAT
TGTTATATTAAAATTTTTATTGTTGTATTAAAGTACCTGTGTTACACCCCTTGAAGTAAGACAGTAGCATGGGGTAAAGAAAAAATATTT
AGTTTAGTTGCCTAATTTGGAAGTTAATTAAAATTAAACTGTACTAATAACATATTCAAACTCATGCTGGATCTCTTTCATATTAATTTC
TTATAGACCTGTACTTTATTCTTTCAATAATTTTTAAATGAAATTAAGCTTTGCTACATGGTAATTAAATAATTACTAGGAAGCTTAGCT
ATCAAACATCGACTTACTAAAATTTCATTTTAGCTTTTATGGTATATGTGCTTGTTTTCTGAATATGGATACATGTTACTTTTGATCCAG
CATCAAAACTTCACTTTTTGTTTTGACTTTTCCCCCCAAATCTGTAAGGTTCAAGTATACATATTACTGAATCCTCTATAATTGGCATAA
TTCAATGGTAGCCTTAAATCTCATCATGTAAGCAGGGGAATCAGAATGTTATTTTCAAGAACTTAATGTTCCCTTCAGATATATAAAATC
CTGCATACTTCATTTCCTGTGAGCTTGAACAGCTGCTGTTGTGTTTTGGGGATGCTTGATCATCTTTGCACTCTGCCTTAAAGATTGAAA
AATCAAAACTCTTGTTAGGGTATCTAAACATTTTTGAGTGTGAACTGGGGATTGGAAGTTAATACAAAAAAATTTCAAATTATTTCTATT
GTAAATGAATAAGCTAGTCATGGCTAGGATAATCCATTTTCATGTATTTATGCAATAAACTGAATTTTAAGGCAAAAACAACACTTTTCT
ATATAGTGTATGCAGGACAGATTTTAGAAACTTAGATTAAAATACAAATCCCATTACATTTGGTTAAAATGAAAATCTCTGCTTAATGGA
AAAAATACTAATCTTTAGCCTATTTTGAGTCTATAAGATATATTTCATTTTAGACATGCCTTCTAAGTTGTTCACAGATTTTTACCTGCT
AAAACAATATTATTTCCAGTAAAACCTCTCCTAACAGGAAAAGTGGAGTTCAAAATATCCAATTGGAGAAAAATTCAGAGTTCCTTCATT
AAATATAATTTTTTTCATCTAGTATGTACTATTTCAAGAAGTGCAAAAAGTAATGATAGTGAATGTGATACCATACTTAACTAAGGTAAT
ATATATCCTTAGTTTGCTCAAAAGAGTCCTGGTTATTCCTGTTTTCTCAGCTTAATAGTGCCTCATCGTACTCTCAAAAGTGTTCTAATT
TGGAGGATAAGTTATATGATCATCCTGTGTATAATTGTAGACTGTACCAAGAAGCAACTACCTTAGCTCCACTGCCCTTTGAGGGATGGA
ACTGGGGTAAGGGCAGGAGCCAGTTATTATTGCCACAGTGTTTTCTAATGAACCATTTGGCCTGTAGAAGAGGAATAGTATTTTTTTTAA
TAGTTGTATTTGAATGATTCCAGCTTATCGTAAATACTAAACTGAATGGCTTTTATATTTTTAACTGCTGTTAAATGTTATTTTAGCATT
TATTAGTTGTTTATTATTTAATTCTTCAAATAGTCATATGAAAACATATATTTGATAAAGGTCAATTGTTAGATGATAATGTGCCATTCA
TTATCATAGGAATGTCCTTGCCCATATATAAAACATGCTGGCATGTATTTTACTTGTTAATAAAGTTGTATAGATGTGGAAGTGTGAACC
TGTGATGCATCCTTTTCAAAATCAGTTTAAGATTCGCATATTATCATGACTGTGACCTCACTAAACTGTTTATGTGACAAACCTTTCAAG
ATTGGAGATGAAAACAACACTTGTGAAATTAGGTTGGGGTTGCAACATCTTTTAACTTCTCAGTTATTTGTATGTCAGGAGACAGATTGT

>57426_57426_4_NBEA-NDFIP2_NBEA_chr13_35517251_ENST00000540320_NDFIP2_chr13_80094945_ENST00000218652_length(amino acids)=365AA_BP=136
MVDAGAPRRRPGGGGRGRYNGTGGGSAAALPFSSGGGPMASEKPGPGPGLEPQPVGLIAVGAAGGGGGGSGGGGTGGSGMGELRGASGSG
SVMLPAGMINPSVPIRNIRMKFAVLIGLIQVGEVSNRDIVETVLNLLLNEEDNSESSAIEQPPTSNPAPQIVQAASSAPALETDSSPPPY
SSITVEVPTTSDTEVYGEFYPVPPPYSVATSLPTYDEAEKAKAAAMAAAAAETSQRIQEEECPPRDDFSDADQLRVGNDGIFMLAFFMAF
IFNWLGFCLSFCITNTIAGRYGAICGFGLSLIKWILIVRFSDYFTGYFNGQYWLWWIFLVLGLLLFFRGFVNYLKVRNMSESMAAAHRTR

--------------------------------------------------------------

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Fusion Gene PPI Analysis for NBEA-NDFIP2


check button Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in

ChiPPI page.


check button Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160)
HgeneHgene's interactorsTgeneTgene's interactors


check button - Retained PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenStill interaction with


check button - Lost PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


check button - Retained PPIs, but lost function due to frame-shift fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


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Related Drugs for NBEA-NDFIP2


check button Drugs targeting genes involved in this fusion gene.
(DrugBank Version 5.1.8 2021-05-08)
PartnerGeneUniProtAccDrugBank IDDrug nameDrug activityDrug typeDrug status

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Related Diseases for NBEA-NDFIP2


check button Diseases associated with fusion partners.
(DisGeNet 4.0)
PartnerGeneDisease IDDisease name# pubmedsSource