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	Fusion Gene Summary
	Fusion Gene ORF analysis
	Fusion Genomic Features
	Fusion Protein Features
	Fusion Gene Sequence
	Fusion Gene PPI analysis
	Related Drugs
	Related Diseases

Fusion gene:ARAP3-CTBP2 (FusionGDB2 ID:5773)

Fusion Gene Summary for ARAP3-CTBP2

Fusion gene summary

Fusion gene information	Fusion gene name: ARAP3-CTBP2
	Fusion gene ID: 5773
		Hgene	Tgene
	Gene symbol	ARAP3	CTBP2
	Gene ID	64411	1488
	Gene name	ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 3	C-terminal binding protein 2
	Synonyms	CENTD3\|DRAG1	-
	Cytomap	5q31.3	10q26.13
	Type of gene	protein-coding	protein-coding
	Description	arf-GAP with Rho-GAP domain, ANK repeat and PH domain-containing protein 3ARF-GAP, RHO-GAP, ankyrin repeat and plekstrin homology domains-containing protein 3Arf and Rho GAP adapter protein 3PtdIns(3,4,5)P3-binding proteincentaurin-delta-3phosphoinos	C-terminal-binding protein 2ribeye
	Modification date	20200327	20200313
	UniProtAcc	Q8WWN8	P56545
	Ensembl transtripts involved in fusion gene	ENST00000239440, ENST00000508305, ENST00000513878, ENST00000512390,	ENST00000309035, ENST00000334808, ENST00000476817, ENST00000337195, ENST00000411419, ENST00000494626, ENST00000531469,
Fusion gene scores	* DoF score	3 X 3 X 3=27	11 X 9 X 4=396
	# samples	3	13
	** MAII score	log2(3/27*10)=0.15200309344505 effective Gene in Pan-Cancer Fusion Genes (eGinPCFGs). DoF>8 and MAII>0	log2(13/396*10)=-1.60698880705116 possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs). DoF>8 and MAII<0
Context	PubMed: ARAP3 [Title/Abstract] AND CTBP2 [Title/Abstract] AND fusion [Title/Abstract]
Most frequent breakpoint	ARAP3(141045991)-CTBP2(126678267), # samples:2
Anticipated loss of major functional domain due to fusion event.	ARAP3-CTBP2 seems lost the major protein functional domain in Hgene partner, which is a essential gene due to the frame-shifted ORF. ARAP3-CTBP2 seems lost the major protein functional domain in Tgene partner, which is a epigenetic factor due to the frame-shifted ORF. ARAP3-CTBP2 seems lost the major protein functional domain in Tgene partner, which is a essential gene due to the frame-shifted ORF.

* DoF score (Degree of Frequency) = # partners X # break points X # cancer types
** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)

Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez

Partner

Gene

GO ID

GO term

PubMed ID

Fusion gene breakpoints across ARAP3 (5'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.

Fusion gene breakpoints across CTBP2 (3'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.

Fusion gene information from two resources (ChiTars 5.0 and ChimerDB 4.0)
* All genome coordinats were lifted-over on hg19.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.

Source	Disease	Sample	Hgene	Hchr	Hbp	Hstrand	Tgene	Tchr	Tbp	Tstrand
ChimerDB4	UCEC	TCGA-AP-A5FX-01A	ARAP3	chr5	141045991	-	CTBP2	chr10	126678267	-

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Fusion Gene ORF analysis for ARAP3-CTBP2

Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.

ORF	Henst	Tenst	Hgene	Hchr	Hbp	Hstrand	Tgene	Tchr	Tbp	Tstrand
5CDS-intron	ENST00000239440	ENST00000309035	ARAP3	chr5	141045991	-	CTBP2	chr10	126678267	-
5CDS-intron	ENST00000239440	ENST00000334808	ARAP3	chr5	141045991	-	CTBP2	chr10	126678267	-
5CDS-intron	ENST00000239440	ENST00000476817	ARAP3	chr5	141045991	-	CTBP2	chr10	126678267	-
5CDS-intron	ENST00000508305	ENST00000309035	ARAP3	chr5	141045991	-	CTBP2	chr10	126678267	-
5CDS-intron	ENST00000508305	ENST00000334808	ARAP3	chr5	141045991	-	CTBP2	chr10	126678267	-
5CDS-intron	ENST00000508305	ENST00000476817	ARAP3	chr5	141045991	-	CTBP2	chr10	126678267	-
5CDS-intron	ENST00000513878	ENST00000309035	ARAP3	chr5	141045991	-	CTBP2	chr10	126678267	-
5CDS-intron	ENST00000513878	ENST00000334808	ARAP3	chr5	141045991	-	CTBP2	chr10	126678267	-
5CDS-intron	ENST00000513878	ENST00000476817	ARAP3	chr5	141045991	-	CTBP2	chr10	126678267	-
5UTR-3CDS	ENST00000512390	ENST00000337195	ARAP3	chr5	141045991	-	CTBP2	chr10	126678267	-
5UTR-3CDS	ENST00000512390	ENST00000411419	ARAP3	chr5	141045991	-	CTBP2	chr10	126678267	-
5UTR-3CDS	ENST00000512390	ENST00000494626	ARAP3	chr5	141045991	-	CTBP2	chr10	126678267	-
5UTR-3CDS	ENST00000512390	ENST00000531469	ARAP3	chr5	141045991	-	CTBP2	chr10	126678267	-
5UTR-intron	ENST00000512390	ENST00000309035	ARAP3	chr5	141045991	-	CTBP2	chr10	126678267	-
5UTR-intron	ENST00000512390	ENST00000334808	ARAP3	chr5	141045991	-	CTBP2	chr10	126678267	-
5UTR-intron	ENST00000512390	ENST00000476817	ARAP3	chr5	141045991	-	CTBP2	chr10	126678267	-
Frame-shift	ENST00000239440	ENST00000337195	ARAP3	chr5	141045991	-	CTBP2	chr10	126678267	-
Frame-shift	ENST00000239440	ENST00000411419	ARAP3	chr5	141045991	-	CTBP2	chr10	126678267	-
Frame-shift	ENST00000239440	ENST00000531469	ARAP3	chr5	141045991	-	CTBP2	chr10	126678267	-
Frame-shift	ENST00000508305	ENST00000494626	ARAP3	chr5	141045991	-	CTBP2	chr10	126678267	-
Frame-shift	ENST00000513878	ENST00000494626	ARAP3	chr5	141045991	-	CTBP2	chr10	126678267	-
In-frame	ENST00000239440	ENST00000494626	ARAP3	chr5	141045991	-	CTBP2	chr10	126678267	-
In-frame	ENST00000508305	ENST00000337195	ARAP3	chr5	141045991	-	CTBP2	chr10	126678267	-
In-frame	ENST00000508305	ENST00000411419	ARAP3	chr5	141045991	-	CTBP2	chr10	126678267	-
In-frame	ENST00000508305	ENST00000531469	ARAP3	chr5	141045991	-	CTBP2	chr10	126678267	-
In-frame	ENST00000513878	ENST00000337195	ARAP3	chr5	141045991	-	CTBP2	chr10	126678267	-
In-frame	ENST00000513878	ENST00000411419	ARAP3	chr5	141045991	-	CTBP2	chr10	126678267	-
In-frame	ENST00000513878	ENST00000531469	ARAP3	chr5	141045991	-	CTBP2	chr10	126678267	-

ORFfinder result based on the fusion transcript sequence of in-frame fusion genes.

Henst	Tenst	Hgene	Hchr	Hbp	Hstrand	Tgene	Tchr	Tbp	Tstrand	Seq length (transcript)	BP loci (transcript)	Predicted start (transcript)	Predicted stop (transcript)	Seq length (amino acids)
ENST00000508305	ARAP3	chr5	141045991	-	ENST00000337195	CTBP2	chr10	126678267	-	4375	2528	34	2610	858
ENST00000508305	ARAP3	chr5	141045991	-	ENST00000531469	CTBP2	chr10	126678267	-	3002	2528	34	2610	858
ENST00000508305	ARAP3	chr5	141045991	-	ENST00000411419	CTBP2	chr10	126678267	-	3002	2528	34	2610	858
ENST00000239440	ARAP3	chr5	141045991	-	ENST00000494626	CTBP2	chr10	126678267	-	3112	2638	66	2720	884
ENST00000513878	ARAP3	chr5	141045991	-	ENST00000337195	CTBP2	chr10	126678267	-	3474	1627	54	1709	551
ENST00000513878	ARAP3	chr5	141045991	-	ENST00000531469	CTBP2	chr10	126678267	-	2101	1627	54	1709	551
ENST00000513878	ARAP3	chr5	141045991	-	ENST00000411419	CTBP2	chr10	126678267	-	2101	1627	54	1709	551

DeepORF prediction of the coding potential based on the fusion transcript sequence of in-frame fusion genes. DeepORF is a coding potential classifier based on convolutional neural network by comparing the real Ribo-seq data. If the no-coding score < 0.5 and coding score > 0.5, then the in-frame fusion transcript is predicted as being likely translated.

Henst	Tenst	Hgene	Hchr	Hbp	Hstrand	Tgene	Tchr	Tbp	Tstrand	No-coding score	Coding score
ENST00000508305	ENST00000337195	ARAP3	chr5	141045991	-	CTBP2	chr10	126678267	-	0.004115798	0.9958841
ENST00000508305	ENST00000531469	ARAP3	chr5	141045991	-	CTBP2	chr10	126678267	-	0.015352499	0.9846475
ENST00000508305	ENST00000411419	ARAP3	chr5	141045991	-	CTBP2	chr10	126678267	-	0.015352499	0.9846475
ENST00000239440	ENST00000494626	ARAP3	chr5	141045991	-	CTBP2	chr10	126678267	-	0.014228651	0.9857714
ENST00000513878	ENST00000337195	ARAP3	chr5	141045991	-	CTBP2	chr10	126678267	-	0.05559494	0.9444051
ENST00000513878	ENST00000531469	ARAP3	chr5	141045991	-	CTBP2	chr10	126678267	-	0.20850664	0.7914934
ENST00000513878	ENST00000411419	ARAP3	chr5	141045991	-	CTBP2	chr10	126678267	-	0.20850664	0.7914934

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Fusion Genomic Features for ARAP3-CTBP2

FusionAI prediction of the potential fusion gene breakpoint based on the pre-mature RNA sequence context (+/- 5kb of individual partner genes, total 20kb length sequence). FusionAI is a fusion gene breakpoint classifier based on convolutional neural network by comparing the fusion positive and negative sequence context of ~ 20K fusion gene data. From here, we can have the relative potentency of the 20K genomic sequence how individual sequnce will be likely used as the gene fusion breakpoints.

Hgene

Hchr

Hbp

Hstrand

Tgene

Tchr

Tbp

Tstrand

1-p

p (fusion gene breakpoint)

Distribution of 44 human genomic features loci across 20kb length fusion breakpoint regions. We integrated a total of 44 different types of human genomic feature loci information across five big categories including virus integration sites, repeats, structural variants, chromatin states, and gene expression regulation. More details are in help page.

Distribution of 44 human genomic features loci across 20kb length fusion breakpoint regions that are ovelapped with the top 1% feature importance score regions. More details are in help page.

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Fusion Protein Features for ARAP3-CTBP2

Four levels of functional features of fusion genes
Go to FGviewer search page for the most frequent breakpoint (https://ccsmweb.uth.edu/FGviewer/chr5:141045991/chr10:126678267)
- FGviewer provides the online visualization of the retention search of the protein functional features across DNA, RNA, protein, and pathological levels.
- How to search
1. Put your fusion gene symbol.
2. Press the tab key until there will be shown the breakpoint information filled.
4. Go down and press 'Search' tab twice.
4. Go down to have the hyperlink of the search result.
5. Click the hyperlink.
6. See the FGviewer result for your fusion gene.

Main function of each fusion partner protein. (from UniProt)

Hgene	Tgene
ARAP3 Q8WWN8	CTBP2 P56545
FUNCTION: Phosphatidylinositol 3,4,5-trisphosphate-dependent GTPase-activating protein that modulates actin cytoskeleton remodeling by regulating ARF and RHO family members. Is activated by phosphatidylinositol 3,4,5-trisphosphate (PtdIns(3,4,5)P3) binding. Can be activated by phosphatidylinositol 3,4-bisphosphate (PtdIns(3,4,5)P2) binding, albeit with lower efficiency. Acts on ARF6, RAC1, RHOA and CDC42. Plays a role in the internalization of anthrax toxin. {ECO:0000269\|PubMed:11804589, ECO:0000269\|PubMed:15569923}.	FUNCTION: Corepressor targeting diverse transcription regulators. Functions in brown adipose tissue (BAT) differentiation (By similarity). {ECO:0000250}.; FUNCTION: Isoform 2 probably acts as a scaffold for specialized synapses.

Retention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at
download page

* Minus value of BPloci means that the break pointn is located before the CDS.

- In-frame and retained protein feature among the 13 regional features.

Partner

Gene

Hbp

Tbp

ENST

Strand

BPexon

TotalExon

Protein feature loci

*BPloci

TotalLen

Protein feature

Protein feature note

Hgene

ARAP3

chr5:141045991

chr10:126678267

ENST00000239440

81_139

857

1545.0

Compositional bias

Note=Pro-rich

Hgene

ARAP3

chr5:141045991

chr10:126678267

ENST00000239440

287_379

857

1545.0

Domain

PH 1

Hgene

ARAP3

chr5:141045991

chr10:126678267

ENST00000239440

394_483

857

1545.0

Domain

PH 2

Hgene

ARAP3

chr5:141045991

chr10:126678267

ENST00000239440

480_611

857

1545.0

Domain

Arf-GAP

Hgene

ARAP3

chr5:141045991

chr10:126678267

ENST00000239440

4_68

857

1545.0

Domain

SAM

Hgene

ARAP3

chr5:141045991

chr10:126678267

ENST00000239440

504_527

857

1545.0

Zinc finger

C4-type

- In-frame and not-retained protein feature among the 13 regional features.

Partner

Gene

Hbp

Tbp

ENST

Strand

BPexon

TotalExon

Protein feature loci

*BPloci

TotalLen

Protein feature

Protein feature note

Hgene

ARAP3

chr5:141045991

chr10:126678267

ENST00000239440

1462_1542

857

1545.0

Compositional bias

Note=Pro-rich

Hgene

ARAP3

chr5:141045991

chr10:126678267

ENST00000239440

1117_1210

857

1545.0

Domain

Ras-associating

Hgene

ARAP3

chr5:141045991

chr10:126678267

ENST00000239440

1223_1325

857

1545.0

Domain

PH 3

Hgene

ARAP3

chr5:141045991

chr10:126678267

ENST00000239440

907_1088

857

1545.0

Domain

Rho-GAP

Tgene

CTBP2

chr5:141045991

chr10:126678267

ENST00000309035

186_191

925

986.0

Nucleotide binding

NAD

Tgene

CTBP2

chr5:141045991

chr10:126678267

ENST00000309035

243_249

925

986.0

Nucleotide binding

NAD

Tgene

CTBP2

chr5:141045991

chr10:126678267

ENST00000309035

270_272

925

986.0

Nucleotide binding

NAD

Tgene

CTBP2

chr5:141045991

chr10:126678267

ENST00000309035

321_324

925

986.0

Nucleotide binding

NAD

Tgene

CTBP2

chr5:141045991

chr10:126678267

ENST00000337195

186_191

385

446.0

Nucleotide binding

NAD

Tgene

CTBP2

chr5:141045991

chr10:126678267

ENST00000337195

243_249

385

446.0

Nucleotide binding

NAD

Tgene

CTBP2

chr5:141045991

chr10:126678267

ENST00000337195

270_272

385

446.0

Nucleotide binding

NAD

Tgene

CTBP2

chr5:141045991

chr10:126678267

ENST00000337195

321_324

385

446.0

Nucleotide binding

NAD

Tgene

CTBP2

chr5:141045991

chr10:126678267

ENST00000411419

186_191

385

446.0

Nucleotide binding

NAD

Tgene

CTBP2

chr5:141045991

chr10:126678267

ENST00000411419

243_249

385

446.0

Nucleotide binding

NAD

Tgene

CTBP2

chr5:141045991

chr10:126678267

ENST00000411419

270_272

385

446.0

Nucleotide binding

NAD

Tgene

CTBP2

chr5:141045991

chr10:126678267

ENST00000411419

321_324

385

446.0

Nucleotide binding

NAD

Tgene

CTBP2

chr5:141045991

chr10:126678267

ENST00000494626

186_191

385

446.0

Nucleotide binding

NAD

Tgene

CTBP2

chr5:141045991

chr10:126678267

ENST00000494626

243_249

385

446.0

Nucleotide binding

NAD

Tgene

CTBP2

chr5:141045991

chr10:126678267

ENST00000494626

270_272

385

446.0

Nucleotide binding

NAD

Tgene

CTBP2

chr5:141045991

chr10:126678267

ENST00000494626

321_324

385

446.0

Nucleotide binding

NAD

Tgene

CTBP2

chr5:141045991

chr10:126678267

ENST00000531469

186_191

385

446.0

Nucleotide binding

NAD

Tgene

CTBP2

chr5:141045991

chr10:126678267

ENST00000531469

243_249

385

446.0

Nucleotide binding

NAD

Tgene

CTBP2

chr5:141045991

chr10:126678267

ENST00000531469

270_272

385

446.0

Nucleotide binding

NAD

Tgene

CTBP2

chr5:141045991

chr10:126678267

ENST00000531469

321_324

385

446.0

Nucleotide binding

NAD

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Fusion Gene Sequence for ARAP3-CTBP2

For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. To have fusion amino acid sequence, we ran ORFfinder and chose the longest ORF among the all predicted ones.

>5773_5773_1_ARAP3-CTBP2_ARAP3_chr5_141045991_ENST00000239440_CTBP2_chr10_126678267_ENST00000494626_length(transcript)=3112nt_BP=2638nt
CTCGGACGAGCGGCGGGCACCCGCGAGCGGACGGCGGCCGCGTAGTGAGCAATGGCCTGAGCCCCCATGGCTGCCCCTCAGGACCTGGAC
ATCGCTGTGTGGCTGGCCACGGTGCACCTGGAGCAGTATGCAGACACGTTCCGACGGCATGGCCTGGCTACAGCAGGTGCAGCCCGGGGC
CTGGGCCACGAGGAGTTGAAGCAGTTGGGCATCAGCGCCACAGGGCACCGGAAACGCATTCTACGCCTGCTACAGACAGGCACCGAAGAG
GGCTCCCTGGATCCCAAATCAGATAGTGCCATGGAACCATCCCCCAGCCCAGCCCCGCAAGCCCAGCCCCCTAAGCCCGTGCCGAAGCCC
AGGACCGTGTTTGGTGGACTCAGTGGCCCTGCCACCACTCAGAGACCTGGGCTGAGCCCAGCCCTCGGGGGACCAGGAGTGTCCAGGAGC
CCAGAGCCCAGCCCAAGGCCTCCTCCTCTCCCCACTTCCTCCTCTGAGCAGTCTTCAGCCCTAAATACTGTGGAGATGATGCCTAATTCC
ATCTACTTCGGCCTGGACTCAAGAGGCAGGGCACAGGCAGCTCAGGACAAGGCCCCAGACAGCTCCCAAATCTCTGCCCCCACCCCTGCC
CTCAGGCCCACAACAGGCACAGTGCACATCATGGATCCTGGTTGCCTGTACTATGGTGTCCAACCTGTGGGGACTCCAGGAGCCCCCGAC
AGAAGAGAGAGCAGAGGTGTTTGTCAGGGCAGGGCTGAACACAGGCTCAGCAGACAGGATCTGGAGGCACGGGAGGATGCTGGCTATGCC
AGCCTTGAGCTACCTGGAGACTCCACCCTCTTATCGCCCACCCTGGAAACAGAGGAGACCAGTGATGACCTCATTTCACCCTATGCCAGC
TTCTCCTTCACGGCAGACCGCCTCACGCCCCTGCTCAGTGGCTGGCTAGACAAGCTCTCCCCTCAGGGAAACTATGTCTTCCAGAGACGC
TTTGTGCAGTTCAATGGGAGGAGTCTGATGTACTTTGGCAGTGACAAGGACCCCTTCCCTAAGGGTGTGATACCTTTGACTGCCATTGAG
ATGACCCGCAGCAGCAAGGACAACAAGTTCCAGGTCATCACCGGCCAGAGGGTGTTCGTGTTCCGCACAGAGAGCGAGGCTCAGCGGGAC
ATGTGGTGCTCCACGCTGCAGTCCTGTCTGAAGGAGCAGCGCCTCCTGGGCCACCCCCGGCCCCCCCAACCACCCCGACCCCTCCGCACG
GGCATGCTGGAGCTGCGTGGACACAAGGCCAAGGTGTTTGCTGCCTTGAGCCCTGGAGAGCTGGCACTGTACAAGAGTGAGCAGGCCTTC
TCTCTGGGCATCGGGATCTGCTTCATCGAACTGCAGGGCTGCAGCGTCCGGGAGACCAAGAGTCGAAGCTTTGACCTGCTCACACCCCAT
CGCTGCTTCAGCTTCACAGCCGAGTCTGGGGGTGCTCGGCAGAGCTGGGCGGCCGCTCTGCAGGAAGCAGTAACCGAGACCCTGTCTGAC
TACGAGGTGGCTGAGAAGATCTGGTCTAATCGGGCCAACCGGCAGTGTGCGGACTGTGGGTCCTCCCGCCCAGATTGGGCTGCTGTCAAT
TTGGGGGTGGTCATCTGCAAGCAGTGTGCAGGTCAGCACCGGGCCCTGGGTTCTGGGATCTCCAAGGTGCAGAGCCTGAAGCTGGACACG
AGTGTCTGGAGTAATGAGATAGTACAGTTATTCATTGTCCTGGGAAATGATCGTGCCAACCGCTTCTGGGCAGGGACCCTACCCCCAGGT
GAGGGACTACATCCAGATGCGACCCCTGGCCCCCGGGGAGAGTTCATCTCCCGAAAGTACCGTCTGGGTCTCTTCCGGAAGCCCCACCCT
CAGTACCCAGATCATAGCCAGCTTCTCCAGGCACTGTGTGCAGCTGTGGCAAGACCCAACCTGCTGAAGAACATGACCCAGCTCCTCTGT
GTTGAGGCCTTTGAAGGCGAGGAGCCCTGGTTCCCCCCAGCCCCTGATGGCAGCTGCCCTGGCCTCTTGCCCTCAGACCCCTCCCCTGGT
GTGTACAATGAGGTGGTGGTGCGTGCTACTTACAGCGGCTTCCTGTACTGCAGTCCCGTCAGCAACAAAGCTGGACCCTCACCCCCTCGC
AGGGGCCGGGATGCTCCCCCGCGCCTTTGGTGTGTGCTGGGAGCAGCTCTGGAAATGTTTGCATCGGAAAACAGCCCTGAACCCCTCAGC
CTCATACAGCCCCAGGATATTGTATGTCTGGGTGTGAGCCCCCCACCCACTGACCCAGGTGACAGGTTCCCCTTTTCCTTTGAGCTCATC
CTCGCTGGGGGGAGGATCCAGCATTTTGGCACAGATGGAGCTGACAGTCTGGAGGCCTGGACTAGTGCTGTGGGCAAGTGGTTCTCCCCG
CTGAGCTGCCACCAGCTGCTGGGCCCCGGGCTGCTGCGGCTGGGCCGCCTATGGCTGCGGTCCCCCTCCCATACAGCCCCGGCCCCTGGT
CTCTGGCTGTCAGGGTTTGGCCTCCTTCGTGGTGACCACCTCTTCCTGTGCTCAGCGCCGGGCCCAGGCCCCCCAGCCCCTGAGGACATG
GTGCATCTGCGGCGGCTACAGGAGATCAATATCCGCCAGGCATCGTGGGTGTGGCTCCAGGAGGACTTCCTGCAGCCATGGAAGGGATCA
TCCCTGGAGGCATCCCAGTGACTCACAACCTCCCGACAGTGGCACATCCTTCCCAAGCGCCCTCTCCCAACCAGCCCACAAAACACGGGG
ACAATCGAGAGCACCCCAACGAGCAATAGCAGAGAATGCCAGAAGGTAATCACTCAGATACACTTGGGACCAAGAGACAGTGAAAAATAG
ATGAACTAAGAGAAAAAGAATCGGATGGTCTTTGTAACTGATTCTGGACATATGCATCATTGATGTTGCAGTGTTGAAACTACAAGAGCT
AGAAAACTGAAGATGTCGTCTGCTTACGGAAGCGCTGAAAGACTAGGATGTGATTTATTAACGACCAACTTCTGTTATTGTGTGTTAAGT

>5773_5773_1_ARAP3-CTBP2_ARAP3_chr5_141045991_ENST00000239440_CTBP2_chr10_126678267_ENST00000494626_length(amino acids)=884AA_BP=858
MAAPQDLDIAVWLATVHLEQYADTFRRHGLATAGAARGLGHEELKQLGISATGHRKRILRLLQTGTEEGSLDPKSDSAMEPSPSPAPQAQ
PPKPVPKPRTVFGGLSGPATTQRPGLSPALGGPGVSRSPEPSPRPPPLPTSSSEQSSALNTVEMMPNSIYFGLDSRGRAQAAQDKAPDSS
QISAPTPALRPTTGTVHIMDPGCLYYGVQPVGTPGAPDRRESRGVCQGRAEHRLSRQDLEAREDAGYASLELPGDSTLLSPTLETEETSD
DLISPYASFSFTADRLTPLLSGWLDKLSPQGNYVFQRRFVQFNGRSLMYFGSDKDPFPKGVIPLTAIEMTRSSKDNKFQVITGQRVFVFR
TESEAQRDMWCSTLQSCLKEQRLLGHPRPPQPPRPLRTGMLELRGHKAKVFAALSPGELALYKSEQAFSLGIGICFIELQGCSVRETKSR
SFDLLTPHRCFSFTAESGGARQSWAAALQEAVTETLSDYEVAEKIWSNRANRQCADCGSSRPDWAAVNLGVVICKQCAGQHRALGSGISK
VQSLKLDTSVWSNEIVQLFIVLGNDRANRFWAGTLPPGEGLHPDATPGPRGEFISRKYRLGLFRKPHPQYPDHSQLLQALCAAVARPNLL
KNMTQLLCVEAFEGEEPWFPPAPDGSCPGLLPSDPSPGVYNEVVVRATYSGFLYCSPVSNKAGPSPPRRGRDAPPRLWCVLGAALEMFAS
ENSPEPLSLIQPQDIVCLGVSPPPTDPGDRFPFSFELILAGGRIQHFGTDGADSLEAWTSAVGKWFSPLSCHQLLGPGLLRLGRLWLRSP

--------------------------------------------------------------
>5773_5773_2_ARAP3-CTBP2_ARAP3_chr5_141045991_ENST00000508305_CTBP2_chr10_126678267_ENST00000337195_length(transcript)=4375nt_BP=2528nt
ACCCGCGAGCGGACGGCGGCCGCGTAGTGAGGACCTGGACATCGCTGTGTGGCTGGCCACGGTGCACCTGGAGCAGTATGCAGACACGTT
CCGACGGCATGGCCTGGCTACAGCAGGTGCAGCCCGGGGCCTGGGCCACGAGGAGTTGAAGCAGTTGGGCATCAGCGCCACAGGGCACCG
GAAACGCATTCTACGCCTGCTACAGACAGGCACCGAAGAGGGCTCCCTGGATCCCAAATCAGATAGTGCCATGGAACCATCCCCCAGCCC
AGCCCCGCAAGCCCAGCCCCCTAAGCCCGTGCCGAAGCCCAGGACCGTGTTTGGTGGACTCAGTGGCCCTGCCACCACTCAGAGACCTGG
GCTGAGCCCAGCCCTCGGGGGACCAGGAGTGTCCAGGAGCCCAGAGCCCAGCCCAAGGCCTCCTCCTCTCCCCACTTCCTCCTCTGAGCA
GTCTTCAGCCCTAAATACTGTGGAGATGATGCCTAATTCCATCTACTTCGGCCTGGACTCAAGAGGCAGGGCACAGGCAGCTCAGGACAA
GGCCCCAGACAGCTCCCAAATCTCTGCCCCCACCCCTGCCCTCAGGCCCACAACAGGCACAGTGCACATCATGGATCCTGGTTGCCTGTA
CTATGGTGTCCAACCTGTGGGGACTCCAGGAGCCCCCGACAGAAGAGAGAGCAGAGGTGTTTGTCAGGGCAGGGCTGAACACAGGCTCAG
CAGACAGGATCTGGAGGCACGGGAGGATGCTGGCTATGCCAGCCTTGAGCTACCTGGAGACTCCACCCTCTTATCGCCCACCCTGGAAAC
AGAGGAGACCAGTGATGACCTCATTTCACCCTATGCCAGCTTCTCCTTCACGGCAGACCGCCTCACGCCCCTGCTCAGTGGCTGGCTAGA
CAAGCTCTCCCCTCAGGGAAACTATGTCTTCCAGAGACGCTTTGTGCAGTTCAATGGGAGGAGTCTGATGTACTTTGGCAGTGACAAGGA
CCCCTTCCCTAAGGGTGTGATACCTTTGACTGCCATTGAGATGACCCGCAGCAGCAAGGACAACAAGTTCCAGGTCATCACCGGCCAGAG
GGTGTTCGTGTTCCGCACAGAGAGCGAGGCTCAGCGGGACATGTGGTGCTCCACGCTGCAGTCCTGTCTGAAGGAGCAGCGCCTCCTGGG
CCACCCCCGGCCCCCCCAACCACCCCGACCCCTCCGCACGGGCATGCTGGAGCTGCGTGGACACAAGGCCAAGGTGTTTGCTGCCTTGAG
CCCTGGAGAGCTGGCACTGTACAAGAGTGAGCAGGCCTTCTCTCTGGGCATCGGGATCTGCTTCATCGAACTGCAGGGCTGCAGCGTCCG
GGAGACCAAGAGTCGAAGCTTTGACCTGCTCACACCCCATCGCTGCTTCAGCTTCACAGCCGAGTCTGGGGGTGCTCGGCAGAGCTGGGC
GGCCGCTCTGCAGGAAGCAGTAACCGAGACCCTGTCTGACTACGAGGTGGCTGAGAAGATCTGGTCTAATCGGGCCAACCGGCAGTGTGC
GGACTGTGGGTCCTCCCGCCCAGATTGGGCTGCTGTCAATTTGGGGGTGGTCATCTGCAAGCAGTGTGCAGGTCAGCACCGGGCCCTGGG
TTCTGGGATCTCCAAGGTGCAGAGCCTGAAGCTGGACACGAGTGTCTGGAGTAATGAGATAGTACAGTTATTCATTGTCCTGGGAAATGA
TCGTGCCAACCGCTTCTGGGCAGGGACCCTACCCCCAGGTGAGGGACTACATCCAGATGCGACCCCTGGCCCCCGGGGAGAGTTCATCTC
CCGAAAGTACCGTCTGGGTCTCTTCCGGAAGCCCCACCCTCAGTACCCAGATCATAGCCAGCTTCTCCAGGCACTGTGTGCAGCTGTGGC
AAGACCCAACCTGCTGAAGAACATGACCCAGCTCCTCTGTGTTGAGGCCTTTGAAGACCCCTCCCCTGGTGTGTACAATGAGGTGGTGGT
GCGTGCTACTTACAGCGGCTTCCTGTACTGCAGTCCCGTCAGCAACAAAGCTGGACCCTCACCCCCTCGCAGGGGCCGGGATGCTCCCCC
GCGCCTTTGGTGTGTGCTGGGAGCAGCTCTGGAAATGTTTGCATCGGAAAACAGCCCTGAACCCCTCAGCCTCATACAGCCCCAGGATAT
TGTATGTCTGGGTGTGAGCCCCCCACCCACTGACCCAGGTGACAGGTTCCCCTTTTCCTTTGAGCTCATCCTCGCTGGGGGGAGGATCCA
GCATTTTGGCACAGATGGAGCTGACAGTCTGGAGGCCTGGACTAGTGCTGTGGGCAAGTGGTTCTCCCCGCTGAGCTGCCACCAGCTGCT
GGGCCCCGGGCTGCTGCGGCTGGGCCGCCTATGGCTGCGGTCCCCCTCCCATACAGCCCCGGCCCCTGGTCTCTGGCTGTCAGGGTTTGG
CCTCCTTCGTGGTGACCACCTCTTCCTGTGCTCAGCGCCGGGCCCAGGCCCCCCAGCCCCTGAGGACATGGTGCATCTGCGGCGGCTACA
GGAGATCAATATCCGCCAGGCATCGTGGGTGTGGCTCCAGGAGGACTTCCTGCAGCCATGGAAGGGATCATCCCTGGAGGCATCCCAGTG
ACTCACAACCTCCCGACAGTGGCACATCCTTCCCAAGCGCCCTCTCCCAACCAGCCCACAAAACACGGGGACAATCGAGAGCACCCCAAC
GAGCAATAGCAGAGAATGCCAGAAGGTAATCACTCAGATACACTTGGGACCAAGAGACAGTGAAAAATAGATGAACTAAGAGAAAAAGAA
TCGGATGGTCTTTGTAACTGATTCTGGACATATGCATCATTGATGTTGCAGTGTTGAAACTACAAGAGCTAGAAAACTGAAGATGTCGTC
TGCTTACGGAAGCGCTGAAAGACTAGGATGTGATTTATTAACGACCAACTTCTGTTATTGTGTGTTAAGTTTTTCATCTGTGCATCAAAT
CACAAAAAGAATAAATAGAGCTTTTTCCTTTATCAGTCCCTTGGGCACAGCAGGTCCTGAACACCCTGCTCTACAATGTTGCATCAAGAG
TTCAAACAACAAAATAAAAAATATTAAGAGGAAATCCCCATCCTGTGACTTGAGTCCCTTAAGTCTACAGGGGCTGGTGACCTCTTTTTG
CTAATAGGAAAATCACATTACTACAAAATGGGGAGAAAACTGTTTGCCTGTGGTAGACACCTGCACGCATAGGATTGAAGACAGTACAGG
CTGCTGTACAGAGAAGCGCCTCTCACATCTGAACTGCATACTGAGCGGGCAAGTCGGTTGTAAGTTCAGTAAAACCCTCTGATGATGCAA
AAAAAAAAAAAAAAGTATTAAGTTTCACAAGCTGTTTGTACTCAAATATATTTTCTCAGTTTCAGATCCTCTGCTATTTTATTGAGTGGA
AAGTCTTGAGCTAAAAGGGTTCAAGAAGAATAATGTTGCATTTCCTTATGTCTCAGGAAACACTTTTTATGGTAACTTGTCAGATTGTCT
ATGAACAAACCCACTTTTTTAGACATTGATAAAGTCTTCTTTTCTTCACGTGATATTTTATACAAGAACACTTCAGATGTATTAGATGTG
ACTGATTTTAACAAATCCTATTAGATTTGTATCAACTAGTTACATGTTCTATTCATAGTCTTTTGTGAATCATTGCCTTTTTGTTTAAAA
AGATGGCCTATTTTGAGCCTTTGTATAGGTACATTCCTGTTTTTGTGACAAAAGAAAAACTTTAAAATTGTCCCAAACAGAAAAATAATG
GCTATCAGAAGTATGTTTTGTTTTAGTGTGAGTTACCGTTACTGTATTTGTTTATTGTAAAGGTGGACATTTAGCGTTCAGTGCAGTTTT
CAATAAAAAGTAATTAAAATTTGTTAAGTTCTGAAATTCAAGTACATCTCACTAATGTAAATGTTCTCTACTTGAGATGTTTAAGGCAAT
TGCATTGTCAATTAGCCAATTTCCAGCTCTTGTTACTACAGGGTTCCATAACCAGACTCAAGACCGCTGACAATTAATTACCTGTGATAA
CAAAAAGTTTAATTGAAAAATCAAAACCTCACACAAGTCCATCATTATCACGTCATGCCATCCTTAAGATGCAATGGTGGGTTAGTGCTA
AATCAATTCAAAAAAAAACAAAGTTGCTCAACTTTTAGAGTTCTGACTTTAATCTACCCCAAAGCAAAATGACCTGGACCTGGTTCAAGG
GAGGGAAGTGAACCTTGAAACTGTTTTGCCAATAACCTAACAAACAAAATGATATTTACAAAGAAGTGTTGCAAATAGTCCCATGAGTTA

>5773_5773_2_ARAP3-CTBP2_ARAP3_chr5_141045991_ENST00000508305_CTBP2_chr10_126678267_ENST00000337195_length(amino acids)=858AA_BP=832
MDIAVWLATVHLEQYADTFRRHGLATAGAARGLGHEELKQLGISATGHRKRILRLLQTGTEEGSLDPKSDSAMEPSPSPAPQAQPPKPVP
KPRTVFGGLSGPATTQRPGLSPALGGPGVSRSPEPSPRPPPLPTSSSEQSSALNTVEMMPNSIYFGLDSRGRAQAAQDKAPDSSQISAPT
PALRPTTGTVHIMDPGCLYYGVQPVGTPGAPDRRESRGVCQGRAEHRLSRQDLEAREDAGYASLELPGDSTLLSPTLETEETSDDLISPY
ASFSFTADRLTPLLSGWLDKLSPQGNYVFQRRFVQFNGRSLMYFGSDKDPFPKGVIPLTAIEMTRSSKDNKFQVITGQRVFVFRTESEAQ
RDMWCSTLQSCLKEQRLLGHPRPPQPPRPLRTGMLELRGHKAKVFAALSPGELALYKSEQAFSLGIGICFIELQGCSVRETKSRSFDLLT
PHRCFSFTAESGGARQSWAAALQEAVTETLSDYEVAEKIWSNRANRQCADCGSSRPDWAAVNLGVVICKQCAGQHRALGSGISKVQSLKL
DTSVWSNEIVQLFIVLGNDRANRFWAGTLPPGEGLHPDATPGPRGEFISRKYRLGLFRKPHPQYPDHSQLLQALCAAVARPNLLKNMTQL
LCVEAFEDPSPGVYNEVVVRATYSGFLYCSPVSNKAGPSPPRRGRDAPPRLWCVLGAALEMFASENSPEPLSLIQPQDIVCLGVSPPPTD
PGDRFPFSFELILAGGRIQHFGTDGADSLEAWTSAVGKWFSPLSCHQLLGPGLLRLGRLWLRSPSHTAPAPGLWLSGFGLLRGDHLFLCS

--------------------------------------------------------------
>5773_5773_3_ARAP3-CTBP2_ARAP3_chr5_141045991_ENST00000508305_CTBP2_chr10_126678267_ENST00000411419_length(transcript)=3002nt_BP=2528nt
ACCCGCGAGCGGACGGCGGCCGCGTAGTGAGGACCTGGACATCGCTGTGTGGCTGGCCACGGTGCACCTGGAGCAGTATGCAGACACGTT
CCGACGGCATGGCCTGGCTACAGCAGGTGCAGCCCGGGGCCTGGGCCACGAGGAGTTGAAGCAGTTGGGCATCAGCGCCACAGGGCACCG
GAAACGCATTCTACGCCTGCTACAGACAGGCACCGAAGAGGGCTCCCTGGATCCCAAATCAGATAGTGCCATGGAACCATCCCCCAGCCC
AGCCCCGCAAGCCCAGCCCCCTAAGCCCGTGCCGAAGCCCAGGACCGTGTTTGGTGGACTCAGTGGCCCTGCCACCACTCAGAGACCTGG
GCTGAGCCCAGCCCTCGGGGGACCAGGAGTGTCCAGGAGCCCAGAGCCCAGCCCAAGGCCTCCTCCTCTCCCCACTTCCTCCTCTGAGCA
GTCTTCAGCCCTAAATACTGTGGAGATGATGCCTAATTCCATCTACTTCGGCCTGGACTCAAGAGGCAGGGCACAGGCAGCTCAGGACAA
GGCCCCAGACAGCTCCCAAATCTCTGCCCCCACCCCTGCCCTCAGGCCCACAACAGGCACAGTGCACATCATGGATCCTGGTTGCCTGTA
CTATGGTGTCCAACCTGTGGGGACTCCAGGAGCCCCCGACAGAAGAGAGAGCAGAGGTGTTTGTCAGGGCAGGGCTGAACACAGGCTCAG
CAGACAGGATCTGGAGGCACGGGAGGATGCTGGCTATGCCAGCCTTGAGCTACCTGGAGACTCCACCCTCTTATCGCCCACCCTGGAAAC
AGAGGAGACCAGTGATGACCTCATTTCACCCTATGCCAGCTTCTCCTTCACGGCAGACCGCCTCACGCCCCTGCTCAGTGGCTGGCTAGA
CAAGCTCTCCCCTCAGGGAAACTATGTCTTCCAGAGACGCTTTGTGCAGTTCAATGGGAGGAGTCTGATGTACTTTGGCAGTGACAAGGA
CCCCTTCCCTAAGGGTGTGATACCTTTGACTGCCATTGAGATGACCCGCAGCAGCAAGGACAACAAGTTCCAGGTCATCACCGGCCAGAG
GGTGTTCGTGTTCCGCACAGAGAGCGAGGCTCAGCGGGACATGTGGTGCTCCACGCTGCAGTCCTGTCTGAAGGAGCAGCGCCTCCTGGG
CCACCCCCGGCCCCCCCAACCACCCCGACCCCTCCGCACGGGCATGCTGGAGCTGCGTGGACACAAGGCCAAGGTGTTTGCTGCCTTGAG
CCCTGGAGAGCTGGCACTGTACAAGAGTGAGCAGGCCTTCTCTCTGGGCATCGGGATCTGCTTCATCGAACTGCAGGGCTGCAGCGTCCG
GGAGACCAAGAGTCGAAGCTTTGACCTGCTCACACCCCATCGCTGCTTCAGCTTCACAGCCGAGTCTGGGGGTGCTCGGCAGAGCTGGGC
GGCCGCTCTGCAGGAAGCAGTAACCGAGACCCTGTCTGACTACGAGGTGGCTGAGAAGATCTGGTCTAATCGGGCCAACCGGCAGTGTGC
GGACTGTGGGTCCTCCCGCCCAGATTGGGCTGCTGTCAATTTGGGGGTGGTCATCTGCAAGCAGTGTGCAGGTCAGCACCGGGCCCTGGG
TTCTGGGATCTCCAAGGTGCAGAGCCTGAAGCTGGACACGAGTGTCTGGAGTAATGAGATAGTACAGTTATTCATTGTCCTGGGAAATGA
TCGTGCCAACCGCTTCTGGGCAGGGACCCTACCCCCAGGTGAGGGACTACATCCAGATGCGACCCCTGGCCCCCGGGGAGAGTTCATCTC
CCGAAAGTACCGTCTGGGTCTCTTCCGGAAGCCCCACCCTCAGTACCCAGATCATAGCCAGCTTCTCCAGGCACTGTGTGCAGCTGTGGC
AAGACCCAACCTGCTGAAGAACATGACCCAGCTCCTCTGTGTTGAGGCCTTTGAAGACCCCTCCCCTGGTGTGTACAATGAGGTGGTGGT
GCGTGCTACTTACAGCGGCTTCCTGTACTGCAGTCCCGTCAGCAACAAAGCTGGACCCTCACCCCCTCGCAGGGGCCGGGATGCTCCCCC
GCGCCTTTGGTGTGTGCTGGGAGCAGCTCTGGAAATGTTTGCATCGGAAAACAGCCCTGAACCCCTCAGCCTCATACAGCCCCAGGATAT
TGTATGTCTGGGTGTGAGCCCCCCACCCACTGACCCAGGTGACAGGTTCCCCTTTTCCTTTGAGCTCATCCTCGCTGGGGGGAGGATCCA
GCATTTTGGCACAGATGGAGCTGACAGTCTGGAGGCCTGGACTAGTGCTGTGGGCAAGTGGTTCTCCCCGCTGAGCTGCCACCAGCTGCT
GGGCCCCGGGCTGCTGCGGCTGGGCCGCCTATGGCTGCGGTCCCCCTCCCATACAGCCCCGGCCCCTGGTCTCTGGCTGTCAGGGTTTGG
CCTCCTTCGTGGTGACCACCTCTTCCTGTGCTCAGCGCCGGGCCCAGGCCCCCCAGCCCCTGAGGACATGGTGCATCTGCGGCGGCTACA
GGAGATCAATATCCGCCAGGCATCGTGGGTGTGGCTCCAGGAGGACTTCCTGCAGCCATGGAAGGGATCATCCCTGGAGGCATCCCAGTG
ACTCACAACCTCCCGACAGTGGCACATCCTTCCCAAGCGCCCTCTCCCAACCAGCCCACAAAACACGGGGACAATCGAGAGCACCCCAAC
GAGCAATAGCAGAGAATGCCAGAAGGTAATCACTCAGATACACTTGGGACCAAGAGACAGTGAAAAATAGATGAACTAAGAGAAAAAGAA
TCGGATGGTCTTTGTAACTGATTCTGGACATATGCATCATTGATGTTGCAGTGTTGAAACTACAAGAGCTAGAAAACTGAAGATGTCGTC
TGCTTACGGAAGCGCTGAAAGACTAGGATGTGATTTATTAACGACCAACTTCTGTTATTGTGTGTTAAGTTTTTCATCTGTGCATCAAAT

>5773_5773_3_ARAP3-CTBP2_ARAP3_chr5_141045991_ENST00000508305_CTBP2_chr10_126678267_ENST00000411419_length(amino acids)=858AA_BP=832
MDIAVWLATVHLEQYADTFRRHGLATAGAARGLGHEELKQLGISATGHRKRILRLLQTGTEEGSLDPKSDSAMEPSPSPAPQAQPPKPVP
KPRTVFGGLSGPATTQRPGLSPALGGPGVSRSPEPSPRPPPLPTSSSEQSSALNTVEMMPNSIYFGLDSRGRAQAAQDKAPDSSQISAPT
PALRPTTGTVHIMDPGCLYYGVQPVGTPGAPDRRESRGVCQGRAEHRLSRQDLEAREDAGYASLELPGDSTLLSPTLETEETSDDLISPY
ASFSFTADRLTPLLSGWLDKLSPQGNYVFQRRFVQFNGRSLMYFGSDKDPFPKGVIPLTAIEMTRSSKDNKFQVITGQRVFVFRTESEAQ
RDMWCSTLQSCLKEQRLLGHPRPPQPPRPLRTGMLELRGHKAKVFAALSPGELALYKSEQAFSLGIGICFIELQGCSVRETKSRSFDLLT
PHRCFSFTAESGGARQSWAAALQEAVTETLSDYEVAEKIWSNRANRQCADCGSSRPDWAAVNLGVVICKQCAGQHRALGSGISKVQSLKL
DTSVWSNEIVQLFIVLGNDRANRFWAGTLPPGEGLHPDATPGPRGEFISRKYRLGLFRKPHPQYPDHSQLLQALCAAVARPNLLKNMTQL
LCVEAFEDPSPGVYNEVVVRATYSGFLYCSPVSNKAGPSPPRRGRDAPPRLWCVLGAALEMFASENSPEPLSLIQPQDIVCLGVSPPPTD
PGDRFPFSFELILAGGRIQHFGTDGADSLEAWTSAVGKWFSPLSCHQLLGPGLLRLGRLWLRSPSHTAPAPGLWLSGFGLLRGDHLFLCS

--------------------------------------------------------------
>5773_5773_4_ARAP3-CTBP2_ARAP3_chr5_141045991_ENST00000508305_CTBP2_chr10_126678267_ENST00000531469_length(transcript)=3002nt_BP=2528nt
ACCCGCGAGCGGACGGCGGCCGCGTAGTGAGGACCTGGACATCGCTGTGTGGCTGGCCACGGTGCACCTGGAGCAGTATGCAGACACGTT
CCGACGGCATGGCCTGGCTACAGCAGGTGCAGCCCGGGGCCTGGGCCACGAGGAGTTGAAGCAGTTGGGCATCAGCGCCACAGGGCACCG
GAAACGCATTCTACGCCTGCTACAGACAGGCACCGAAGAGGGCTCCCTGGATCCCAAATCAGATAGTGCCATGGAACCATCCCCCAGCCC
AGCCCCGCAAGCCCAGCCCCCTAAGCCCGTGCCGAAGCCCAGGACCGTGTTTGGTGGACTCAGTGGCCCTGCCACCACTCAGAGACCTGG
GCTGAGCCCAGCCCTCGGGGGACCAGGAGTGTCCAGGAGCCCAGAGCCCAGCCCAAGGCCTCCTCCTCTCCCCACTTCCTCCTCTGAGCA
GTCTTCAGCCCTAAATACTGTGGAGATGATGCCTAATTCCATCTACTTCGGCCTGGACTCAAGAGGCAGGGCACAGGCAGCTCAGGACAA
GGCCCCAGACAGCTCCCAAATCTCTGCCCCCACCCCTGCCCTCAGGCCCACAACAGGCACAGTGCACATCATGGATCCTGGTTGCCTGTA
CTATGGTGTCCAACCTGTGGGGACTCCAGGAGCCCCCGACAGAAGAGAGAGCAGAGGTGTTTGTCAGGGCAGGGCTGAACACAGGCTCAG
CAGACAGGATCTGGAGGCACGGGAGGATGCTGGCTATGCCAGCCTTGAGCTACCTGGAGACTCCACCCTCTTATCGCCCACCCTGGAAAC
AGAGGAGACCAGTGATGACCTCATTTCACCCTATGCCAGCTTCTCCTTCACGGCAGACCGCCTCACGCCCCTGCTCAGTGGCTGGCTAGA
CAAGCTCTCCCCTCAGGGAAACTATGTCTTCCAGAGACGCTTTGTGCAGTTCAATGGGAGGAGTCTGATGTACTTTGGCAGTGACAAGGA
CCCCTTCCCTAAGGGTGTGATACCTTTGACTGCCATTGAGATGACCCGCAGCAGCAAGGACAACAAGTTCCAGGTCATCACCGGCCAGAG
GGTGTTCGTGTTCCGCACAGAGAGCGAGGCTCAGCGGGACATGTGGTGCTCCACGCTGCAGTCCTGTCTGAAGGAGCAGCGCCTCCTGGG
CCACCCCCGGCCCCCCCAACCACCCCGACCCCTCCGCACGGGCATGCTGGAGCTGCGTGGACACAAGGCCAAGGTGTTTGCTGCCTTGAG
CCCTGGAGAGCTGGCACTGTACAAGAGTGAGCAGGCCTTCTCTCTGGGCATCGGGATCTGCTTCATCGAACTGCAGGGCTGCAGCGTCCG
GGAGACCAAGAGTCGAAGCTTTGACCTGCTCACACCCCATCGCTGCTTCAGCTTCACAGCCGAGTCTGGGGGTGCTCGGCAGAGCTGGGC
GGCCGCTCTGCAGGAAGCAGTAACCGAGACCCTGTCTGACTACGAGGTGGCTGAGAAGATCTGGTCTAATCGGGCCAACCGGCAGTGTGC
GGACTGTGGGTCCTCCCGCCCAGATTGGGCTGCTGTCAATTTGGGGGTGGTCATCTGCAAGCAGTGTGCAGGTCAGCACCGGGCCCTGGG
TTCTGGGATCTCCAAGGTGCAGAGCCTGAAGCTGGACACGAGTGTCTGGAGTAATGAGATAGTACAGTTATTCATTGTCCTGGGAAATGA
TCGTGCCAACCGCTTCTGGGCAGGGACCCTACCCCCAGGTGAGGGACTACATCCAGATGCGACCCCTGGCCCCCGGGGAGAGTTCATCTC
CCGAAAGTACCGTCTGGGTCTCTTCCGGAAGCCCCACCCTCAGTACCCAGATCATAGCCAGCTTCTCCAGGCACTGTGTGCAGCTGTGGC
AAGACCCAACCTGCTGAAGAACATGACCCAGCTCCTCTGTGTTGAGGCCTTTGAAGACCCCTCCCCTGGTGTGTACAATGAGGTGGTGGT
GCGTGCTACTTACAGCGGCTTCCTGTACTGCAGTCCCGTCAGCAACAAAGCTGGACCCTCACCCCCTCGCAGGGGCCGGGATGCTCCCCC
GCGCCTTTGGTGTGTGCTGGGAGCAGCTCTGGAAATGTTTGCATCGGAAAACAGCCCTGAACCCCTCAGCCTCATACAGCCCCAGGATAT
TGTATGTCTGGGTGTGAGCCCCCCACCCACTGACCCAGGTGACAGGTTCCCCTTTTCCTTTGAGCTCATCCTCGCTGGGGGGAGGATCCA
GCATTTTGGCACAGATGGAGCTGACAGTCTGGAGGCCTGGACTAGTGCTGTGGGCAAGTGGTTCTCCCCGCTGAGCTGCCACCAGCTGCT
GGGCCCCGGGCTGCTGCGGCTGGGCCGCCTATGGCTGCGGTCCCCCTCCCATACAGCCCCGGCCCCTGGTCTCTGGCTGTCAGGGTTTGG
CCTCCTTCGTGGTGACCACCTCTTCCTGTGCTCAGCGCCGGGCCCAGGCCCCCCAGCCCCTGAGGACATGGTGCATCTGCGGCGGCTACA
GGAGATCAATATCCGCCAGGCATCGTGGGTGTGGCTCCAGGAGGACTTCCTGCAGCCATGGAAGGGATCATCCCTGGAGGCATCCCAGTG
ACTCACAACCTCCCGACAGTGGCACATCCTTCCCAAGCGCCCTCTCCCAACCAGCCCACAAAACACGGGGACAATCGAGAGCACCCCAAC
GAGCAATAGCAGAGAATGCCAGAAGGTAATCACTCAGATACACTTGGGACCAAGAGACAGTGAAAAATAGATGAACTAAGAGAAAAAGAA
TCGGATGGTCTTTGTAACTGATTCTGGACATATGCATCATTGATGTTGCAGTGTTGAAACTACAAGAGCTAGAAAACTGAAGATGTCGTC
TGCTTACGGAAGCGCTGAAAGACTAGGATGTGATTTATTAACGACCAACTTCTGTTATTGTGTGTTAAGTTTTTCATCTGTGCATCAAAT

>5773_5773_4_ARAP3-CTBP2_ARAP3_chr5_141045991_ENST00000508305_CTBP2_chr10_126678267_ENST00000531469_length(amino acids)=858AA_BP=832
MDIAVWLATVHLEQYADTFRRHGLATAGAARGLGHEELKQLGISATGHRKRILRLLQTGTEEGSLDPKSDSAMEPSPSPAPQAQPPKPVP
KPRTVFGGLSGPATTQRPGLSPALGGPGVSRSPEPSPRPPPLPTSSSEQSSALNTVEMMPNSIYFGLDSRGRAQAAQDKAPDSSQISAPT
PALRPTTGTVHIMDPGCLYYGVQPVGTPGAPDRRESRGVCQGRAEHRLSRQDLEAREDAGYASLELPGDSTLLSPTLETEETSDDLISPY
ASFSFTADRLTPLLSGWLDKLSPQGNYVFQRRFVQFNGRSLMYFGSDKDPFPKGVIPLTAIEMTRSSKDNKFQVITGQRVFVFRTESEAQ
RDMWCSTLQSCLKEQRLLGHPRPPQPPRPLRTGMLELRGHKAKVFAALSPGELALYKSEQAFSLGIGICFIELQGCSVRETKSRSFDLLT
PHRCFSFTAESGGARQSWAAALQEAVTETLSDYEVAEKIWSNRANRQCADCGSSRPDWAAVNLGVVICKQCAGQHRALGSGISKVQSLKL
DTSVWSNEIVQLFIVLGNDRANRFWAGTLPPGEGLHPDATPGPRGEFISRKYRLGLFRKPHPQYPDHSQLLQALCAAVARPNLLKNMTQL
LCVEAFEDPSPGVYNEVVVRATYSGFLYCSPVSNKAGPSPPRRGRDAPPRLWCVLGAALEMFASENSPEPLSLIQPQDIVCLGVSPPPTD
PGDRFPFSFELILAGGRIQHFGTDGADSLEAWTSAVGKWFSPLSCHQLLGPGLLRLGRLWLRSPSHTAPAPGLWLSGFGLLRGDHLFLCS

--------------------------------------------------------------
>5773_5773_5_ARAP3-CTBP2_ARAP3_chr5_141045991_ENST00000513878_CTBP2_chr10_126678267_ENST00000337195_length(transcript)=3474nt_BP=1627nt
ATGGGTCATTGAGCTCTCTCTCTCCAGGACCCCTTCCCTAAGGGTGTGATACCTTTGACTGCCATTGAGATGACCCGCAGCAGCAAGGAC
AACAAGTTCCAGGTCATCACCGGCCAGAGGGTGTTCGTGTTCCGCACAGAGAGCGAGGCTCAGCGGGACATGTGGTGCTCCACGCTGCAG
TCCTGTCTGAAGGAGCAGCGCCTCCTGGGCCACCCCCGGCCCCCCCAACCACCCCGACCCCTCCGCACGGGCATGCTGGAGCTGCGTGGA
CACAAGGCCAAGGTGTTTGCTGCCTTGAGCCCTGGAGAGCTGGCACTGTACAAGAGTGAGCAGGCCTTCTCTCTGGGCATCGGGATCTGC
TTCATCGAACTGCAGGGCTGCAGCGTCCGGGAGACCAAGAGTCGAAGCTTTGACCTGCTCACACCCCATCGCTGCTTCAGCTTCACAGCC
GAGTCTGGGGGTGCTCGGCAGAGCTGGGCGGCCGCTCTGCAGGAAGCAGTAACCGAGACCCTGTCTGACTACGAGGTGGCTGAGAAGATC
TGGTCTAATCGGGCCAACCGGCAGTGTGCGGACTGTGGGTCCTCCCGCCCAGATTGGGCTGCTGTCAATTTGGGGGTGGTCATCTGCAAG
CAGTGTGCAGGTCAGCACCGGGCCCTGGGTTCTGGGATCTCCAAGGTGCAGAGCCTGAAGCTGGACACGAGTGTCTGGAGTAATGAGATA
GTACAGTTATTCATTGTCCTGGGAAATGATCGTGCCAACCGCTTCTGGGCAGGGACCCTACCCCCAGGTGAGGGACTACATCCAGATGCG
ACCCCTGGCCCCCGGGGAGAGTTCATCTCCCGAAAGTACCGTCTGGGTCTCTTCCGGAAGCCCCACCCTCAGTACCCAGATCATAGCCAG
CTTCTCCAGGCACTGTGTGCAGCTGTGGCAAGACCCAACCTGCTGAAGAACATGACCCAGCTCCTCTGTGTTGAGGCCTTTGAAGGCGAG
GAGCCCTGGTTCCCCCCAGCCCCTGATGGCAGCTGCCCTGGCCTCTTGCCCTCAGACCCCTCCCCTGGTGTGTACAATGAGGTGGTGGTG
CGTGCTACTTACAGCGGCTTCCTGTACTGCAGTCCCGTCAGCAACAAAGCTGGACCCTCACCCCCTCGCAGGGGCCGGGATGCTCCCCCG
CGCCTTTGGTGTGTGCTGGGAGCAGCTCTGGAAATGTTTGCATCGGAAAACAGCCCTGAACCCCTCAGCCTCATACAGCCCCAGGATATT
GTATGTCTGGGTGTGAGCCCCCCACCCACTGACCCAGGTGACAGGTTCCCCTTTTCCTTTGAGCTCATCCTCGCTGGGGGGAGGATCCAG
CATTTTGGCACAGATGGAGCTGACAGTCTGGAGGCCTGGACTAGTGCTGTGGGCAAGTGGTTCTCCCCGCTGAGCTGCCACCAGCTGCTG
GGCCCCGGGCTGCTGCGGCTGGGCCGCCTATGGCTGCGGTCCCCCTCCCATACAGCCCCGGCCCCTGGTCTCTGGCTGTCAGGGTTTGGC
CTCCTTCGTGGTGACCACCTCTTCCTGTGCTCAGCGCCGGGCCCAGGCCCCCCAGCCCCTGAGGACATGGTGCATCTGCGGCGGCTACAG
GAGATCAATATCCGCCAGGCATCGTGGGTGTGGCTCCAGGAGGACTTCCTGCAGCCATGGAAGGGATCATCCCTGGAGGCATCCCAGTGA
CTCACAACCTCCCGACAGTGGCACATCCTTCCCAAGCGCCCTCTCCCAACCAGCCCACAAAACACGGGGACAATCGAGAGCACCCCAACG
AGCAATAGCAGAGAATGCCAGAAGGTAATCACTCAGATACACTTGGGACCAAGAGACAGTGAAAAATAGATGAACTAAGAGAAAAAGAAT
CGGATGGTCTTTGTAACTGATTCTGGACATATGCATCATTGATGTTGCAGTGTTGAAACTACAAGAGCTAGAAAACTGAAGATGTCGTCT
GCTTACGGAAGCGCTGAAAGACTAGGATGTGATTTATTAACGACCAACTTCTGTTATTGTGTGTTAAGTTTTTCATCTGTGCATCAAATC
ACAAAAAGAATAAATAGAGCTTTTTCCTTTATCAGTCCCTTGGGCACAGCAGGTCCTGAACACCCTGCTCTACAATGTTGCATCAAGAGT
TCAAACAACAAAATAAAAAATATTAAGAGGAAATCCCCATCCTGTGACTTGAGTCCCTTAAGTCTACAGGGGCTGGTGACCTCTTTTTGC
TAATAGGAAAATCACATTACTACAAAATGGGGAGAAAACTGTTTGCCTGTGGTAGACACCTGCACGCATAGGATTGAAGACAGTACAGGC
TGCTGTACAGAGAAGCGCCTCTCACATCTGAACTGCATACTGAGCGGGCAAGTCGGTTGTAAGTTCAGTAAAACCCTCTGATGATGCAAA
AAAAAAAAAAAAAGTATTAAGTTTCACAAGCTGTTTGTACTCAAATATATTTTCTCAGTTTCAGATCCTCTGCTATTTTATTGAGTGGAA
AGTCTTGAGCTAAAAGGGTTCAAGAAGAATAATGTTGCATTTCCTTATGTCTCAGGAAACACTTTTTATGGTAACTTGTCAGATTGTCTA
TGAACAAACCCACTTTTTTAGACATTGATAAAGTCTTCTTTTCTTCACGTGATATTTTATACAAGAACACTTCAGATGTATTAGATGTGA
CTGATTTTAACAAATCCTATTAGATTTGTATCAACTAGTTACATGTTCTATTCATAGTCTTTTGTGAATCATTGCCTTTTTGTTTAAAAA
GATGGCCTATTTTGAGCCTTTGTATAGGTACATTCCTGTTTTTGTGACAAAAGAAAAACTTTAAAATTGTCCCAAACAGAAAAATAATGG
CTATCAGAAGTATGTTTTGTTTTAGTGTGAGTTACCGTTACTGTATTTGTTTATTGTAAAGGTGGACATTTAGCGTTCAGTGCAGTTTTC
AATAAAAAGTAATTAAAATTTGTTAAGTTCTGAAATTCAAGTACATCTCACTAATGTAAATGTTCTCTACTTGAGATGTTTAAGGCAATT
GCATTGTCAATTAGCCAATTTCCAGCTCTTGTTACTACAGGGTTCCATAACCAGACTCAAGACCGCTGACAATTAATTACCTGTGATAAC
AAAAAGTTTAATTGAAAAATCAAAACCTCACACAAGTCCATCATTATCACGTCATGCCATCCTTAAGATGCAATGGTGGGTTAGTGCTAA
ATCAATTCAAAAAAAAACAAAGTTGCTCAACTTTTAGAGTTCTGACTTTAATCTACCCCAAAGCAAAATGACCTGGACCTGGTTCAAGGG
AGGGAAGTGAACCTTGAAACTGTTTTGCCAATAACCTAACAAACAAAATGATATTTACAAAGAAGTGTTGCAAATAGTCCCATGAGTTAA

>5773_5773_5_ARAP3-CTBP2_ARAP3_chr5_141045991_ENST00000513878_CTBP2_chr10_126678267_ENST00000337195_length(amino acids)=551AA_BP=525
MTAIEMTRSSKDNKFQVITGQRVFVFRTESEAQRDMWCSTLQSCLKEQRLLGHPRPPQPPRPLRTGMLELRGHKAKVFAALSPGELALYK
SEQAFSLGIGICFIELQGCSVRETKSRSFDLLTPHRCFSFTAESGGARQSWAAALQEAVTETLSDYEVAEKIWSNRANRQCADCGSSRPD
WAAVNLGVVICKQCAGQHRALGSGISKVQSLKLDTSVWSNEIVQLFIVLGNDRANRFWAGTLPPGEGLHPDATPGPRGEFISRKYRLGLF
RKPHPQYPDHSQLLQALCAAVARPNLLKNMTQLLCVEAFEGEEPWFPPAPDGSCPGLLPSDPSPGVYNEVVVRATYSGFLYCSPVSNKAG
PSPPRRGRDAPPRLWCVLGAALEMFASENSPEPLSLIQPQDIVCLGVSPPPTDPGDRFPFSFELILAGGRIQHFGTDGADSLEAWTSAVG
KWFSPLSCHQLLGPGLLRLGRLWLRSPSHTAPAPGLWLSGFGLLRGDHLFLCSAPGPGPPAPEDMVHLRRLQEINIRQASWVWLQEDFLQ

--------------------------------------------------------------
>5773_5773_6_ARAP3-CTBP2_ARAP3_chr5_141045991_ENST00000513878_CTBP2_chr10_126678267_ENST00000411419_length(transcript)=2101nt_BP=1627nt
ATGGGTCATTGAGCTCTCTCTCTCCAGGACCCCTTCCCTAAGGGTGTGATACCTTTGACTGCCATTGAGATGACCCGCAGCAGCAAGGAC
AACAAGTTCCAGGTCATCACCGGCCAGAGGGTGTTCGTGTTCCGCACAGAGAGCGAGGCTCAGCGGGACATGTGGTGCTCCACGCTGCAG
TCCTGTCTGAAGGAGCAGCGCCTCCTGGGCCACCCCCGGCCCCCCCAACCACCCCGACCCCTCCGCACGGGCATGCTGGAGCTGCGTGGA
CACAAGGCCAAGGTGTTTGCTGCCTTGAGCCCTGGAGAGCTGGCACTGTACAAGAGTGAGCAGGCCTTCTCTCTGGGCATCGGGATCTGC
TTCATCGAACTGCAGGGCTGCAGCGTCCGGGAGACCAAGAGTCGAAGCTTTGACCTGCTCACACCCCATCGCTGCTTCAGCTTCACAGCC
GAGTCTGGGGGTGCTCGGCAGAGCTGGGCGGCCGCTCTGCAGGAAGCAGTAACCGAGACCCTGTCTGACTACGAGGTGGCTGAGAAGATC
TGGTCTAATCGGGCCAACCGGCAGTGTGCGGACTGTGGGTCCTCCCGCCCAGATTGGGCTGCTGTCAATTTGGGGGTGGTCATCTGCAAG
CAGTGTGCAGGTCAGCACCGGGCCCTGGGTTCTGGGATCTCCAAGGTGCAGAGCCTGAAGCTGGACACGAGTGTCTGGAGTAATGAGATA
GTACAGTTATTCATTGTCCTGGGAAATGATCGTGCCAACCGCTTCTGGGCAGGGACCCTACCCCCAGGTGAGGGACTACATCCAGATGCG
ACCCCTGGCCCCCGGGGAGAGTTCATCTCCCGAAAGTACCGTCTGGGTCTCTTCCGGAAGCCCCACCCTCAGTACCCAGATCATAGCCAG
CTTCTCCAGGCACTGTGTGCAGCTGTGGCAAGACCCAACCTGCTGAAGAACATGACCCAGCTCCTCTGTGTTGAGGCCTTTGAAGGCGAG
GAGCCCTGGTTCCCCCCAGCCCCTGATGGCAGCTGCCCTGGCCTCTTGCCCTCAGACCCCTCCCCTGGTGTGTACAATGAGGTGGTGGTG
CGTGCTACTTACAGCGGCTTCCTGTACTGCAGTCCCGTCAGCAACAAAGCTGGACCCTCACCCCCTCGCAGGGGCCGGGATGCTCCCCCG
CGCCTTTGGTGTGTGCTGGGAGCAGCTCTGGAAATGTTTGCATCGGAAAACAGCCCTGAACCCCTCAGCCTCATACAGCCCCAGGATATT
GTATGTCTGGGTGTGAGCCCCCCACCCACTGACCCAGGTGACAGGTTCCCCTTTTCCTTTGAGCTCATCCTCGCTGGGGGGAGGATCCAG
CATTTTGGCACAGATGGAGCTGACAGTCTGGAGGCCTGGACTAGTGCTGTGGGCAAGTGGTTCTCCCCGCTGAGCTGCCACCAGCTGCTG
GGCCCCGGGCTGCTGCGGCTGGGCCGCCTATGGCTGCGGTCCCCCTCCCATACAGCCCCGGCCCCTGGTCTCTGGCTGTCAGGGTTTGGC
CTCCTTCGTGGTGACCACCTCTTCCTGTGCTCAGCGCCGGGCCCAGGCCCCCCAGCCCCTGAGGACATGGTGCATCTGCGGCGGCTACAG
GAGATCAATATCCGCCAGGCATCGTGGGTGTGGCTCCAGGAGGACTTCCTGCAGCCATGGAAGGGATCATCCCTGGAGGCATCCCAGTGA
CTCACAACCTCCCGACAGTGGCACATCCTTCCCAAGCGCCCTCTCCCAACCAGCCCACAAAACACGGGGACAATCGAGAGCACCCCAACG
AGCAATAGCAGAGAATGCCAGAAGGTAATCACTCAGATACACTTGGGACCAAGAGACAGTGAAAAATAGATGAACTAAGAGAAAAAGAAT
CGGATGGTCTTTGTAACTGATTCTGGACATATGCATCATTGATGTTGCAGTGTTGAAACTACAAGAGCTAGAAAACTGAAGATGTCGTCT
GCTTACGGAAGCGCTGAAAGACTAGGATGTGATTTATTAACGACCAACTTCTGTTATTGTGTGTTAAGTTTTTCATCTGTGCATCAAATC

>5773_5773_6_ARAP3-CTBP2_ARAP3_chr5_141045991_ENST00000513878_CTBP2_chr10_126678267_ENST00000411419_length(amino acids)=551AA_BP=525
MTAIEMTRSSKDNKFQVITGQRVFVFRTESEAQRDMWCSTLQSCLKEQRLLGHPRPPQPPRPLRTGMLELRGHKAKVFAALSPGELALYK
SEQAFSLGIGICFIELQGCSVRETKSRSFDLLTPHRCFSFTAESGGARQSWAAALQEAVTETLSDYEVAEKIWSNRANRQCADCGSSRPD
WAAVNLGVVICKQCAGQHRALGSGISKVQSLKLDTSVWSNEIVQLFIVLGNDRANRFWAGTLPPGEGLHPDATPGPRGEFISRKYRLGLF
RKPHPQYPDHSQLLQALCAAVARPNLLKNMTQLLCVEAFEGEEPWFPPAPDGSCPGLLPSDPSPGVYNEVVVRATYSGFLYCSPVSNKAG
PSPPRRGRDAPPRLWCVLGAALEMFASENSPEPLSLIQPQDIVCLGVSPPPTDPGDRFPFSFELILAGGRIQHFGTDGADSLEAWTSAVG
KWFSPLSCHQLLGPGLLRLGRLWLRSPSHTAPAPGLWLSGFGLLRGDHLFLCSAPGPGPPAPEDMVHLRRLQEINIRQASWVWLQEDFLQ

--------------------------------------------------------------
>5773_5773_7_ARAP3-CTBP2_ARAP3_chr5_141045991_ENST00000513878_CTBP2_chr10_126678267_ENST00000531469_length(transcript)=2101nt_BP=1627nt
ATGGGTCATTGAGCTCTCTCTCTCCAGGACCCCTTCCCTAAGGGTGTGATACCTTTGACTGCCATTGAGATGACCCGCAGCAGCAAGGAC
AACAAGTTCCAGGTCATCACCGGCCAGAGGGTGTTCGTGTTCCGCACAGAGAGCGAGGCTCAGCGGGACATGTGGTGCTCCACGCTGCAG
TCCTGTCTGAAGGAGCAGCGCCTCCTGGGCCACCCCCGGCCCCCCCAACCACCCCGACCCCTCCGCACGGGCATGCTGGAGCTGCGTGGA
CACAAGGCCAAGGTGTTTGCTGCCTTGAGCCCTGGAGAGCTGGCACTGTACAAGAGTGAGCAGGCCTTCTCTCTGGGCATCGGGATCTGC
TTCATCGAACTGCAGGGCTGCAGCGTCCGGGAGACCAAGAGTCGAAGCTTTGACCTGCTCACACCCCATCGCTGCTTCAGCTTCACAGCC
GAGTCTGGGGGTGCTCGGCAGAGCTGGGCGGCCGCTCTGCAGGAAGCAGTAACCGAGACCCTGTCTGACTACGAGGTGGCTGAGAAGATC
TGGTCTAATCGGGCCAACCGGCAGTGTGCGGACTGTGGGTCCTCCCGCCCAGATTGGGCTGCTGTCAATTTGGGGGTGGTCATCTGCAAG
CAGTGTGCAGGTCAGCACCGGGCCCTGGGTTCTGGGATCTCCAAGGTGCAGAGCCTGAAGCTGGACACGAGTGTCTGGAGTAATGAGATA
GTACAGTTATTCATTGTCCTGGGAAATGATCGTGCCAACCGCTTCTGGGCAGGGACCCTACCCCCAGGTGAGGGACTACATCCAGATGCG
ACCCCTGGCCCCCGGGGAGAGTTCATCTCCCGAAAGTACCGTCTGGGTCTCTTCCGGAAGCCCCACCCTCAGTACCCAGATCATAGCCAG
CTTCTCCAGGCACTGTGTGCAGCTGTGGCAAGACCCAACCTGCTGAAGAACATGACCCAGCTCCTCTGTGTTGAGGCCTTTGAAGGCGAG
GAGCCCTGGTTCCCCCCAGCCCCTGATGGCAGCTGCCCTGGCCTCTTGCCCTCAGACCCCTCCCCTGGTGTGTACAATGAGGTGGTGGTG
CGTGCTACTTACAGCGGCTTCCTGTACTGCAGTCCCGTCAGCAACAAAGCTGGACCCTCACCCCCTCGCAGGGGCCGGGATGCTCCCCCG
CGCCTTTGGTGTGTGCTGGGAGCAGCTCTGGAAATGTTTGCATCGGAAAACAGCCCTGAACCCCTCAGCCTCATACAGCCCCAGGATATT
GTATGTCTGGGTGTGAGCCCCCCACCCACTGACCCAGGTGACAGGTTCCCCTTTTCCTTTGAGCTCATCCTCGCTGGGGGGAGGATCCAG
CATTTTGGCACAGATGGAGCTGACAGTCTGGAGGCCTGGACTAGTGCTGTGGGCAAGTGGTTCTCCCCGCTGAGCTGCCACCAGCTGCTG
GGCCCCGGGCTGCTGCGGCTGGGCCGCCTATGGCTGCGGTCCCCCTCCCATACAGCCCCGGCCCCTGGTCTCTGGCTGTCAGGGTTTGGC
CTCCTTCGTGGTGACCACCTCTTCCTGTGCTCAGCGCCGGGCCCAGGCCCCCCAGCCCCTGAGGACATGGTGCATCTGCGGCGGCTACAG
GAGATCAATATCCGCCAGGCATCGTGGGTGTGGCTCCAGGAGGACTTCCTGCAGCCATGGAAGGGATCATCCCTGGAGGCATCCCAGTGA
CTCACAACCTCCCGACAGTGGCACATCCTTCCCAAGCGCCCTCTCCCAACCAGCCCACAAAACACGGGGACAATCGAGAGCACCCCAACG
AGCAATAGCAGAGAATGCCAGAAGGTAATCACTCAGATACACTTGGGACCAAGAGACAGTGAAAAATAGATGAACTAAGAGAAAAAGAAT
CGGATGGTCTTTGTAACTGATTCTGGACATATGCATCATTGATGTTGCAGTGTTGAAACTACAAGAGCTAGAAAACTGAAGATGTCGTCT
GCTTACGGAAGCGCTGAAAGACTAGGATGTGATTTATTAACGACCAACTTCTGTTATTGTGTGTTAAGTTTTTCATCTGTGCATCAAATC

>5773_5773_7_ARAP3-CTBP2_ARAP3_chr5_141045991_ENST00000513878_CTBP2_chr10_126678267_ENST00000531469_length(amino acids)=551AA_BP=525
MTAIEMTRSSKDNKFQVITGQRVFVFRTESEAQRDMWCSTLQSCLKEQRLLGHPRPPQPPRPLRTGMLELRGHKAKVFAALSPGELALYK
SEQAFSLGIGICFIELQGCSVRETKSRSFDLLTPHRCFSFTAESGGARQSWAAALQEAVTETLSDYEVAEKIWSNRANRQCADCGSSRPD
WAAVNLGVVICKQCAGQHRALGSGISKVQSLKLDTSVWSNEIVQLFIVLGNDRANRFWAGTLPPGEGLHPDATPGPRGEFISRKYRLGLF
RKPHPQYPDHSQLLQALCAAVARPNLLKNMTQLLCVEAFEGEEPWFPPAPDGSCPGLLPSDPSPGVYNEVVVRATYSGFLYCSPVSNKAG
PSPPRRGRDAPPRLWCVLGAALEMFASENSPEPLSLIQPQDIVCLGVSPPPTDPGDRFPFSFELILAGGRIQHFGTDGADSLEAWTSAVG
KWFSPLSCHQLLGPGLLRLGRLWLRSPSHTAPAPGLWLSGFGLLRGDHLFLCSAPGPGPPAPEDMVHLRRLQEINIRQASWVWLQEDFLQ

--------------------------------------------------------------

Top

Fusion Gene PPI Analysis for ARAP3-CTBP2

Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in
ChiPPI page.

Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160)

Hgene

Hgene's interactors

Tgene

Tgene's interactors

- Retained PPIs in in-frame fusion.

Partner

Gene

Hbp

Tbp

ENST

Strand

BPexon

TotalExon

Protein feature loci

*BPloci

TotalLen

Still interaction with

- Lost PPIs in in-frame fusion.

Partner

Gene

Hbp

Tbp

ENST

Strand

BPexon

TotalExon

Protein feature loci

*BPloci

TotalLen

Interaction lost with

- Retained PPIs, but lost function due to frame-shift fusion.

Partner

Gene

Hbp

Tbp

ENST

Strand

BPexon

TotalExon

Protein feature loci

*BPloci

TotalLen

Interaction lost with

Top

Related Drugs for ARAP3-CTBP2

Drugs targeting genes involved in this fusion gene.
(DrugBank Version 5.1.8 2021-05-08)

Partner

Gene

UniProtAcc

DrugBank ID

Drug name

Drug activity

Drug type

Drug status

Top

Related Diseases for ARAP3-CTBP2

Diseases associated with fusion partners.
(DisGeNet 4.0)

Partner

Gene

Disease ID

Disease name

# pubmeds

Source