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Center for Computational Systems Medicine
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Fusion Gene Summary

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Fusion Gene ORF analysis

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Fusion Genomic Features

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Fusion Protein Features

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Fusion Gene Sequence

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Fusion Gene PPI analysis

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Related Drugs

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Related Diseases

Fusion gene:NCOA3-EYA2 (FusionGDB2 ID:57735)

Fusion Gene Summary for NCOA3-EYA2

check button Fusion gene summary
Fusion gene informationFusion gene name: NCOA3-EYA2
Fusion gene ID: 57735
HgeneTgene
Gene symbol

NCOA3

EYA2

Gene ID

8202

2139

Gene namenuclear receptor coactivator 3EYA transcriptional coactivator and phosphatase 2
SynonymsACTR|AIB-1|AIB1|CAGH16|CTG26|KAT13B|RAC3|SRC-3|SRC3|TNRC14|TNRC16|TRAM-1|bHLHe42|pCIPEAB1
Cytomap

20q13.12

20q13.12

Type of geneprotein-codingprotein-coding
Descriptionnuclear receptor coactivator 3CBP-interacting proteinamplified in breast cancer 1 proteinclass E basic helix-loop-helix protein 42receptor-associated coactivator 3steroid receptor coactivator protein 3thyroid hormone receptor activator molecule 1eyes absent homolog 2
Modification date2020031320200313
UniProtAcc

Q9Y6Q9

O00167

Ensembl transtripts involved in fusion geneENST00000341724, ENST00000371997, 
ENST00000371998, ENST00000372004, 
ENST00000497292, 		ENST00000317304, 
ENST00000497428, ENST00000327619, 
ENST00000357410, 
Fusion gene scores* DoF score27 X 14 X 11=415815 X 15 X 10=2250
# samples 3530
** MAII scorelog2(35/4158*10)=-3.57046293102604
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0		log2(30/2250*10)=-2.90689059560852
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0
Context

PubMed: NCOA3 [Title/Abstract] AND EYA2 [Title/Abstract] AND fusion [Title/Abstract]

Most frequent breakpointNCOA3(46271128)-EYA2(45700824), # samples:2
NCOA3(46130763)-EYA2(45801355), # samples:2
NCOA3(46130763)-EYA2(45618640), # samples:2
Anticipated loss of major functional domain due to fusion event.NCOA3-EYA2 seems lost the major protein functional domain in Hgene partner, which is a cell metabolism gene due to the frame-shifted ORF.
NCOA3-EYA2 seems lost the major protein functional domain in Hgene partner, which is a epigenetic factor due to the frame-shifted ORF.
NCOA3-EYA2 seems lost the major protein functional domain in Hgene partner, which is a IUPHAR drug target due to the frame-shifted ORF.
NCOA3-EYA2 seems lost the major protein functional domain in Hgene partner, which is a transcription factor due to the frame-shifted ORF.
NCOA3-EYA2 seems lost the major protein functional domain in Tgene partner, which is a epigenetic factor due to the frame-shifted ORF.
* DoF score (Degree of Frequency) = # partners X # break points X # cancer types
** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)

check button Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez
PartnerGeneGO IDGO termPubMed ID
HgeneNCOA3

GO:0045944

positive regulation of transcription by RNA polymerase II

9267036

HgeneNCOA3

GO:0071392

cellular response to estradiol stimulus

15831516

TgeneEYA2

GO:0016576

histone dephosphorylation

19351884


check buttonFusion gene breakpoints across NCOA3 (5'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check buttonFusion gene breakpoints across EYA2 (3'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check button Fusion gene information from two resources (ChiTars 5.0 and ChimerDB 4.0)
* All genome coordinats were lifted-over on hg19.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
SourceDiseaseSampleHgeneHchrHbpHstrandTgeneTchrTbpTstrand
ChimerDB4LUADTCGA-55-7727-01ANCOA3chr20

46130763

-EYA2chr20

45618640

+
ChimerDB4LUSCTCGA-37-4133-01ANCOA3chr20

46271128

-EYA2chr20

45700824

+
ChimerDB4LUSCTCGA-37-4133NCOA3chr20

46271128

+EYA2chr20

45700824

+
ChimerDB4OVTCGA-23-1030-01ANCOA3chr20

46130763

-EYA2chr20

45801355

+
ChimerDB4OVTCGA-23-1030-01ANCOA3chr20

46130763

+EYA2chr20

45801355

+
ChimerDB4OVTCGA-23-1030NCOA3chr20

46130763

+EYA2chr20

45801354

+
ChimerDB4OVTCGA-24-2020-01ANCOA3chr20

46130763

+EYA2chr20

45771698

+
ChimerDB4UCECTCGA-A5-A1OH-01ANCOA3chr20

46212005

-EYA2chr20

45618640

+
ChimerDB4UCECTCGA-AP-A053-01ANCOA3chr20

46130763

+EYA2chr20

45618640

+
ChimerDB4UCECTCGA-D1-A179NCOA3chr20

46271128

+EYA2chr20

45700823

+
ChimerDB4UCECTCGA-D1-A179NCOA3chr20

46280020

+EYA2chr20

45717877

+
ChimerDB4UCSTCGA-N5-A4RO-01ANCOA3chr20

46254225

-EYA2chr20

45700824

+


Top

Fusion Gene ORF analysis for NCOA3-EYA2

check button Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
ORFHenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrand
5CDS-intronENST00000341724ENST00000317304NCOA3chr20

46271128

+EYA2chr20

45700824

+
5CDS-intronENST00000341724ENST00000317304NCOA3chr20

46271128

+EYA2chr20

45700823

+
5CDS-intronENST00000341724ENST00000317304NCOA3chr20

46280020

+EYA2chr20

45717877

+
5CDS-intronENST00000341724ENST00000317304NCOA3chr20

46254225

-EYA2chr20

45700824

+
5CDS-intronENST00000341724ENST00000497428NCOA3chr20

46271128

+EYA2chr20

45700824

+
5CDS-intronENST00000341724ENST00000497428NCOA3chr20

46271128

+EYA2chr20

45700823

+
5CDS-intronENST00000341724ENST00000497428NCOA3chr20

46280020

+EYA2chr20

45717877

+
5CDS-intronENST00000341724ENST00000497428NCOA3chr20

46254225

-EYA2chr20

45700824

+
5CDS-intronENST00000371997ENST00000317304NCOA3chr20

46271128

+EYA2chr20

45700824

+
5CDS-intronENST00000371997ENST00000317304NCOA3chr20

46271128

+EYA2chr20

45700823

+
5CDS-intronENST00000371997ENST00000317304NCOA3chr20

46280020

+EYA2chr20

45717877

+
5CDS-intronENST00000371997ENST00000317304NCOA3chr20

46254225

-EYA2chr20

45700824

+
5CDS-intronENST00000371997ENST00000497428NCOA3chr20

46271128

+EYA2chr20

45700824

+
5CDS-intronENST00000371997ENST00000497428NCOA3chr20

46271128

+EYA2chr20

45700823

+
5CDS-intronENST00000371997ENST00000497428NCOA3chr20

46280020

+EYA2chr20

45717877

+
5CDS-intronENST00000371997ENST00000497428NCOA3chr20

46254225

-EYA2chr20

45700824

+
5CDS-intronENST00000371998ENST00000317304NCOA3chr20

46271128

+EYA2chr20

45700824

+
5CDS-intronENST00000371998ENST00000317304NCOA3chr20

46271128

+EYA2chr20

45700823

+
5CDS-intronENST00000371998ENST00000317304NCOA3chr20

46280020

+EYA2chr20

45717877

+
5CDS-intronENST00000371998ENST00000317304NCOA3chr20

46254225

-EYA2chr20

45700824

+
5CDS-intronENST00000371998ENST00000497428NCOA3chr20

46271128

+EYA2chr20

45700824

+
5CDS-intronENST00000371998ENST00000497428NCOA3chr20

46271128

+EYA2chr20

45700823

+
5CDS-intronENST00000371998ENST00000497428NCOA3chr20

46280020

+EYA2chr20

45717877

+
5CDS-intronENST00000371998ENST00000497428NCOA3chr20

46254225

-EYA2chr20

45700824

+
5CDS-intronENST00000372004ENST00000317304NCOA3chr20

46271128

+EYA2chr20

45700824

+
5CDS-intronENST00000372004ENST00000317304NCOA3chr20

46271128

+EYA2chr20

45700823

+
5CDS-intronENST00000372004ENST00000317304NCOA3chr20

46280020

+EYA2chr20

45717877

+
5CDS-intronENST00000372004ENST00000317304NCOA3chr20

46254225

-EYA2chr20

45700824

+
5CDS-intronENST00000372004ENST00000497428NCOA3chr20

46271128

+EYA2chr20

45700824

+
5CDS-intronENST00000372004ENST00000497428NCOA3chr20

46271128

+EYA2chr20

45700823

+
5CDS-intronENST00000372004ENST00000497428NCOA3chr20

46280020

+EYA2chr20

45717877

+
5CDS-intronENST00000372004ENST00000497428NCOA3chr20

46254225

-EYA2chr20

45700824

+
5UTR-3CDSENST00000341724ENST00000327619NCOA3chr20

46130763

+EYA2chr20

45801355

+
5UTR-3CDSENST00000341724ENST00000327619NCOA3chr20

46130763

+EYA2chr20

45801354

+
5UTR-3CDSENST00000341724ENST00000327619NCOA3chr20

46130763

+EYA2chr20

45771698

+
5UTR-3CDSENST00000341724ENST00000357410NCOA3chr20

46130763

+EYA2chr20

45801355

+
5UTR-3CDSENST00000341724ENST00000357410NCOA3chr20

46130763

+EYA2chr20

45801354

+
5UTR-3CDSENST00000341724ENST00000357410NCOA3chr20

46130763

+EYA2chr20

45771698

+
5UTR-3CDSENST00000371997ENST00000327619NCOA3chr20

46130763

+EYA2chr20

45801355

+
5UTR-3CDSENST00000371997ENST00000327619NCOA3chr20

46130763

+EYA2chr20

45801354

+
5UTR-3CDSENST00000371997ENST00000327619NCOA3chr20

46130763

+EYA2chr20

45771698

+
5UTR-3CDSENST00000371997ENST00000357410NCOA3chr20

46130763

+EYA2chr20

45801355

+
5UTR-3CDSENST00000371997ENST00000357410NCOA3chr20

46130763

+EYA2chr20

45801354

+
5UTR-3CDSENST00000371997ENST00000357410NCOA3chr20

46130763

+EYA2chr20

45771698

+
5UTR-3CDSENST00000371998ENST00000327619NCOA3chr20

46130763

+EYA2chr20

45801355

+
5UTR-3CDSENST00000371998ENST00000327619NCOA3chr20

46130763

+EYA2chr20

45801354

+
5UTR-3CDSENST00000371998ENST00000327619NCOA3chr20

46130763

+EYA2chr20

45771698

+
5UTR-3CDSENST00000371998ENST00000357410NCOA3chr20

46130763

+EYA2chr20

45801355

+
5UTR-3CDSENST00000371998ENST00000357410NCOA3chr20

46130763

+EYA2chr20

45801354

+
5UTR-3CDSENST00000371998ENST00000357410NCOA3chr20

46130763

+EYA2chr20

45771698

+
5UTR-3CDSENST00000372004ENST00000327619NCOA3chr20

46130763

+EYA2chr20

45801355

+
5UTR-3CDSENST00000372004ENST00000327619NCOA3chr20

46130763

+EYA2chr20

45801354

+
5UTR-3CDSENST00000372004ENST00000327619NCOA3chr20

46130763

+EYA2chr20

45771698

+
5UTR-3CDSENST00000372004ENST00000357410NCOA3chr20

46130763

+EYA2chr20

45801355

+
5UTR-3CDSENST00000372004ENST00000357410NCOA3chr20

46130763

+EYA2chr20

45801354

+
5UTR-3CDSENST00000372004ENST00000357410NCOA3chr20

46130763

+EYA2chr20

45771698

+
5UTR-3UTRENST00000341724ENST00000317304NCOA3chr20

46212005

-EYA2chr20

45618640

+
5UTR-3UTRENST00000341724ENST00000317304NCOA3chr20

46130763

+EYA2chr20

45618640

+
5UTR-3UTRENST00000341724ENST00000497428NCOA3chr20

46212005

-EYA2chr20

45618640

+
5UTR-3UTRENST00000341724ENST00000497428NCOA3chr20

46130763

+EYA2chr20

45618640

+
5UTR-3UTRENST00000371997ENST00000317304NCOA3chr20

46212005

-EYA2chr20

45618640

+
5UTR-3UTRENST00000371997ENST00000317304NCOA3chr20

46130763

+EYA2chr20

45618640

+
5UTR-3UTRENST00000371997ENST00000497428NCOA3chr20

46212005

-EYA2chr20

45618640

+
5UTR-3UTRENST00000371997ENST00000497428NCOA3chr20

46130763

+EYA2chr20

45618640

+
5UTR-3UTRENST00000371998ENST00000317304NCOA3chr20

46212005

-EYA2chr20

45618640

+
5UTR-3UTRENST00000371998ENST00000317304NCOA3chr20

46130763

+EYA2chr20

45618640

+
5UTR-3UTRENST00000371998ENST00000497428NCOA3chr20

46212005

-EYA2chr20

45618640

+
5UTR-3UTRENST00000371998ENST00000497428NCOA3chr20

46130763

+EYA2chr20

45618640

+
5UTR-3UTRENST00000372004ENST00000317304NCOA3chr20

46212005

-EYA2chr20

45618640

+
5UTR-3UTRENST00000372004ENST00000317304NCOA3chr20

46130763

+EYA2chr20

45618640

+
5UTR-3UTRENST00000372004ENST00000497428NCOA3chr20

46212005

-EYA2chr20

45618640

+
5UTR-3UTRENST00000372004ENST00000497428NCOA3chr20

46130763

+EYA2chr20

45618640

+
5UTR-5UTRENST00000341724ENST00000327619NCOA3chr20

46212005

-EYA2chr20

45618640

+
5UTR-5UTRENST00000341724ENST00000327619NCOA3chr20

46130763

+EYA2chr20

45618640

+
5UTR-5UTRENST00000341724ENST00000357410NCOA3chr20

46212005

-EYA2chr20

45618640

+
5UTR-5UTRENST00000341724ENST00000357410NCOA3chr20

46130763

+EYA2chr20

45618640

+
5UTR-5UTRENST00000371997ENST00000327619NCOA3chr20

46212005

-EYA2chr20

45618640

+
5UTR-5UTRENST00000371997ENST00000327619NCOA3chr20

46130763

+EYA2chr20

45618640

+
5UTR-5UTRENST00000371997ENST00000357410NCOA3chr20

46212005

-EYA2chr20

45618640

+
5UTR-5UTRENST00000371997ENST00000357410NCOA3chr20

46130763

+EYA2chr20

45618640

+
5UTR-5UTRENST00000371998ENST00000327619NCOA3chr20

46212005

-EYA2chr20

45618640

+
5UTR-5UTRENST00000371998ENST00000327619NCOA3chr20

46130763

+EYA2chr20

45618640

+
5UTR-5UTRENST00000371998ENST00000357410NCOA3chr20

46212005

-EYA2chr20

45618640

+
5UTR-5UTRENST00000371998ENST00000357410NCOA3chr20

46130763

+EYA2chr20

45618640

+
5UTR-5UTRENST00000372004ENST00000327619NCOA3chr20

46212005

-EYA2chr20

45618640

+
5UTR-5UTRENST00000372004ENST00000327619NCOA3chr20

46130763

+EYA2chr20

45618640

+
5UTR-5UTRENST00000372004ENST00000357410NCOA3chr20

46212005

-EYA2chr20

45618640

+
5UTR-5UTRENST00000372004ENST00000357410NCOA3chr20

46130763

+EYA2chr20

45618640

+
5UTR-intronENST00000341724ENST00000317304NCOA3chr20

46130763

+EYA2chr20

45801355

+
5UTR-intronENST00000341724ENST00000317304NCOA3chr20

46130763

+EYA2chr20

45801354

+
5UTR-intronENST00000341724ENST00000317304NCOA3chr20

46130763

+EYA2chr20

45771698

+
5UTR-intronENST00000341724ENST00000497428NCOA3chr20

46130763

+EYA2chr20

45801355

+
5UTR-intronENST00000341724ENST00000497428NCOA3chr20

46130763

+EYA2chr20

45801354

+
5UTR-intronENST00000341724ENST00000497428NCOA3chr20

46130763

+EYA2chr20

45771698

+
5UTR-intronENST00000371997ENST00000317304NCOA3chr20

46130763

+EYA2chr20

45801355

+
5UTR-intronENST00000371997ENST00000317304NCOA3chr20

46130763

+EYA2chr20

45801354

+
5UTR-intronENST00000371997ENST00000317304NCOA3chr20

46130763

+EYA2chr20

45771698

+
5UTR-intronENST00000371997ENST00000497428NCOA3chr20

46130763

+EYA2chr20

45801355

+
5UTR-intronENST00000371997ENST00000497428NCOA3chr20

46130763

+EYA2chr20

45801354

+
5UTR-intronENST00000371997ENST00000497428NCOA3chr20

46130763

+EYA2chr20

45771698

+
5UTR-intronENST00000371998ENST00000317304NCOA3chr20

46130763

+EYA2chr20

45801355

+
5UTR-intronENST00000371998ENST00000317304NCOA3chr20

46130763

+EYA2chr20

45801354

+
5UTR-intronENST00000371998ENST00000317304NCOA3chr20

46130763

+EYA2chr20

45771698

+
5UTR-intronENST00000371998ENST00000497428NCOA3chr20

46130763

+EYA2chr20

45801355

+
5UTR-intronENST00000371998ENST00000497428NCOA3chr20

46130763

+EYA2chr20

45801354

+
5UTR-intronENST00000371998ENST00000497428NCOA3chr20

46130763

+EYA2chr20

45771698

+
5UTR-intronENST00000372004ENST00000317304NCOA3chr20

46130763

+EYA2chr20

45801355

+
5UTR-intronENST00000372004ENST00000317304NCOA3chr20

46130763

+EYA2chr20

45801354

+
5UTR-intronENST00000372004ENST00000317304NCOA3chr20

46130763

+EYA2chr20

45771698

+
5UTR-intronENST00000372004ENST00000497428NCOA3chr20

46130763

+EYA2chr20

45801355

+
5UTR-intronENST00000372004ENST00000497428NCOA3chr20

46130763

+EYA2chr20

45801354

+
5UTR-intronENST00000372004ENST00000497428NCOA3chr20

46130763

+EYA2chr20

45771698

+
Frame-shiftENST00000341724ENST00000327619NCOA3chr20

46271128

+EYA2chr20

45700824

+
Frame-shiftENST00000341724ENST00000327619NCOA3chr20

46271128

+EYA2chr20

45700823

+
Frame-shiftENST00000341724ENST00000327619NCOA3chr20

46254225

-EYA2chr20

45700824

+
Frame-shiftENST00000341724ENST00000357410NCOA3chr20

46271128

+EYA2chr20

45700824

+
Frame-shiftENST00000341724ENST00000357410NCOA3chr20

46271128

+EYA2chr20

45700823

+
Frame-shiftENST00000341724ENST00000357410NCOA3chr20

46254225

-EYA2chr20

45700824

+
Frame-shiftENST00000371997ENST00000327619NCOA3chr20

46271128

+EYA2chr20

45700824

+
Frame-shiftENST00000371997ENST00000327619NCOA3chr20

46271128

+EYA2chr20

45700823

+
Frame-shiftENST00000371997ENST00000327619NCOA3chr20

46254225

-EYA2chr20

45700824

+
Frame-shiftENST00000371997ENST00000357410NCOA3chr20

46271128

+EYA2chr20

45700824

+
Frame-shiftENST00000371997ENST00000357410NCOA3chr20

46271128

+EYA2chr20

45700823

+
Frame-shiftENST00000371997ENST00000357410NCOA3chr20

46254225

-EYA2chr20

45700824

+
Frame-shiftENST00000371998ENST00000327619NCOA3chr20

46271128

+EYA2chr20

45700824

+
Frame-shiftENST00000371998ENST00000327619NCOA3chr20

46271128

+EYA2chr20

45700823

+
Frame-shiftENST00000371998ENST00000327619NCOA3chr20

46254225

-EYA2chr20

45700824

+
Frame-shiftENST00000371998ENST00000357410NCOA3chr20

46271128

+EYA2chr20

45700824

+
Frame-shiftENST00000371998ENST00000357410NCOA3chr20

46271128

+EYA2chr20

45700823

+
Frame-shiftENST00000371998ENST00000357410NCOA3chr20

46254225

-EYA2chr20

45700824

+
Frame-shiftENST00000372004ENST00000327619NCOA3chr20

46271128

+EYA2chr20

45700824

+
Frame-shiftENST00000372004ENST00000327619NCOA3chr20

46271128

+EYA2chr20

45700823

+
Frame-shiftENST00000372004ENST00000327619NCOA3chr20

46254225

-EYA2chr20

45700824

+
Frame-shiftENST00000372004ENST00000357410NCOA3chr20

46271128

+EYA2chr20

45700824

+
Frame-shiftENST00000372004ENST00000357410NCOA3chr20

46271128

+EYA2chr20

45700823

+
Frame-shiftENST00000372004ENST00000357410NCOA3chr20

46254225

-EYA2chr20

45700824

+
In-frameENST00000341724ENST00000327619NCOA3chr20

46280020

+EYA2chr20

45717877

+
In-frameENST00000341724ENST00000357410NCOA3chr20

46280020

+EYA2chr20

45717877

+
In-frameENST00000371997ENST00000327619NCOA3chr20

46280020

+EYA2chr20

45717877

+
In-frameENST00000371997ENST00000357410NCOA3chr20

46280020

+EYA2chr20

45717877

+
In-frameENST00000371998ENST00000327619NCOA3chr20

46280020

+EYA2chr20

45717877

+
In-frameENST00000371998ENST00000357410NCOA3chr20

46280020

+EYA2chr20

45717877

+
In-frameENST00000372004ENST00000327619NCOA3chr20

46280020

+EYA2chr20

45717877

+
In-frameENST00000372004ENST00000357410NCOA3chr20

46280020

+EYA2chr20

45717877

+
intron-3CDSENST00000497292ENST00000327619NCOA3chr20

46271128

+EYA2chr20

45700824

+
intron-3CDSENST00000497292ENST00000327619NCOA3chr20

46130763

+EYA2chr20

45801355

+
intron-3CDSENST00000497292ENST00000327619NCOA3chr20

46130763

+EYA2chr20

45801354

+
intron-3CDSENST00000497292ENST00000327619NCOA3chr20

46130763

+EYA2chr20

45771698

+
intron-3CDSENST00000497292ENST00000327619NCOA3chr20

46271128

+EYA2chr20

45700823

+
intron-3CDSENST00000497292ENST00000327619NCOA3chr20

46280020

+EYA2chr20

45717877

+
intron-3CDSENST00000497292ENST00000327619NCOA3chr20

46254225

-EYA2chr20

45700824

+
intron-3CDSENST00000497292ENST00000357410NCOA3chr20

46271128

+EYA2chr20

45700824

+
intron-3CDSENST00000497292ENST00000357410NCOA3chr20

46130763

+EYA2chr20

45801355

+
intron-3CDSENST00000497292ENST00000357410NCOA3chr20

46130763

+EYA2chr20

45801354

+
intron-3CDSENST00000497292ENST00000357410NCOA3chr20

46130763

+EYA2chr20

45771698

+
intron-3CDSENST00000497292ENST00000357410NCOA3chr20

46271128

+EYA2chr20

45700823

+
intron-3CDSENST00000497292ENST00000357410NCOA3chr20

46280020

+EYA2chr20

45717877

+
intron-3CDSENST00000497292ENST00000357410NCOA3chr20

46254225

-EYA2chr20

45700824

+
intron-3UTRENST00000497292ENST00000317304NCOA3chr20

46212005

-EYA2chr20

45618640

+
intron-3UTRENST00000497292ENST00000317304NCOA3chr20

46130763

+EYA2chr20

45618640

+
intron-3UTRENST00000497292ENST00000497428NCOA3chr20

46212005

-EYA2chr20

45618640

+
intron-3UTRENST00000497292ENST00000497428NCOA3chr20

46130763

+EYA2chr20

45618640

+
intron-5UTRENST00000497292ENST00000327619NCOA3chr20

46212005

-EYA2chr20

45618640

+
intron-5UTRENST00000497292ENST00000327619NCOA3chr20

46130763

+EYA2chr20

45618640

+
intron-5UTRENST00000497292ENST00000357410NCOA3chr20

46212005

-EYA2chr20

45618640

+
intron-5UTRENST00000497292ENST00000357410NCOA3chr20

46130763

+EYA2chr20

45618640

+
intron-intronENST00000497292ENST00000317304NCOA3chr20

46271128

+EYA2chr20

45700824

+
intron-intronENST00000497292ENST00000317304NCOA3chr20

46130763

+EYA2chr20

45801355

+
intron-intronENST00000497292ENST00000317304NCOA3chr20

46130763

+EYA2chr20

45801354

+
intron-intronENST00000497292ENST00000317304NCOA3chr20

46130763

+EYA2chr20

45771698

+
intron-intronENST00000497292ENST00000317304NCOA3chr20

46271128

+EYA2chr20

45700823

+
intron-intronENST00000497292ENST00000317304NCOA3chr20

46280020

+EYA2chr20

45717877

+
intron-intronENST00000497292ENST00000317304NCOA3chr20

46254225

-EYA2chr20

45700824

+
intron-intronENST00000497292ENST00000497428NCOA3chr20

46271128

+EYA2chr20

45700824

+
intron-intronENST00000497292ENST00000497428NCOA3chr20

46130763

+EYA2chr20

45801355

+
intron-intronENST00000497292ENST00000497428NCOA3chr20

46130763

+EYA2chr20

45801354

+
intron-intronENST00000497292ENST00000497428NCOA3chr20

46130763

+EYA2chr20

45771698

+
intron-intronENST00000497292ENST00000497428NCOA3chr20

46271128

+EYA2chr20

45700823

+
intron-intronENST00000497292ENST00000497428NCOA3chr20

46280020

+EYA2chr20

45717877

+
intron-intronENST00000497292ENST00000497428NCOA3chr20

46254225

-EYA2chr20

45700824

+

check buttonORFfinder result based on the fusion transcript sequence of in-frame fusion genes.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandSeq length
(transcript)		BP loci
(transcript)		Predicted start
(transcript)		Predicted stop
(transcript)		Seq length
(amino acids)
ENST00000341724NCOA3chr2046280020+ENST00000357410EYA2chr2045717877+5415398526147031480
ENST00000341724NCOA3chr2046280020+ENST00000327619EYA2chr2045717877+5652398526149401559
ENST00000372004NCOA3chr2046280020+ENST00000357410EYA2chr2045717877+5580415021648681550
ENST00000372004NCOA3chr2046280020+ENST00000327619EYA2chr2045717877+5817415021651051629
ENST00000371998NCOA3chr2046280020+ENST00000357410EYA2chr2045717877+5567413719148551554
ENST00000371998NCOA3chr2046280020+ENST00000327619EYA2chr2045717877+5804413719150921633
ENST00000371997NCOA3chr2046280020+ENST00000357410EYA2chr2045717877+5526409617748141545
ENST00000371997NCOA3chr2046280020+ENST00000327619EYA2chr2045717877+5763409617750511624

check buttonDeepORF prediction of the coding potential based on the fusion transcript sequence of in-frame fusion genes. DeepORF is a coding potential classifier based on convolutional neural network by comparing the real Ribo-seq data. If the no-coding score < 0.5 and coding score > 0.5, then the in-frame fusion transcript is predicted as being likely translated.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandNo-coding scoreCoding score
ENST00000341724ENST00000357410NCOA3chr2046280020+EYA2chr2045717877+0.001562520.99843746
ENST00000341724ENST00000327619NCOA3chr2046280020+EYA2chr2045717877+0.0012307690.9987692
ENST00000372004ENST00000357410NCOA3chr2046280020+EYA2chr2045717877+0.001982480.99801755
ENST00000372004ENST00000327619NCOA3chr2046280020+EYA2chr2045717877+0.0010315870.99896836
ENST00000371998ENST00000357410NCOA3chr2046280020+EYA2chr2045717877+0.0013500760.9986499
ENST00000371998ENST00000327619NCOA3chr2046280020+EYA2chr2045717877+0.0015011670.9984988
ENST00000371997ENST00000357410NCOA3chr2046280020+EYA2chr2045717877+0.0019443640.9980557
ENST00000371997ENST00000327619NCOA3chr2046280020+EYA2chr2045717877+0.000743240.9992568

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Fusion Genomic Features for NCOA3-EYA2


check buttonFusionAI prediction of the potential fusion gene breakpoint based on the pre-mature RNA sequence context (+/- 5kb of individual partner genes, total 20kb length sequence). FusionAI is a fusion gene breakpoint classifier based on convolutional neural network by comparing the fusion positive and negative sequence context of ~ 20K fusion gene data. From here, we can have the relative potentency of the 20K genomic sequence how individual sequnce will be likely used as the gene fusion breakpoints.
HgeneHchrHbpHstrandTgeneTchrTbpTstrand1-pp (fusion gene breakpoint)
NCOA3chr2046271128+EYA2chr2045700823+0.0005836620.99941635
NCOA3chr2046271128+EYA2chr2045700823+0.0005836620.99941635
NCOA3chr2046280020+EYA2chr2045717877+1.01E-070.9999999
NCOA3chr2046130763+EYA2chr2045801354+2.99E-131
NCOA3chr2046130763+EYA2chr2045771697+1.43E-081
NCOA3chr2046130763+EYA2chr2045801354+2.99E-131
NCOA3chr2046130763+EYA2chr2045618639+3.16E-111
NCOA3chr2046271128+EYA2chr2045700823+0.0005836620.99941635
NCOA3chr2046271128+EYA2chr2045700823+0.0005836620.99941635
NCOA3chr2046280020+EYA2chr2045717877+1.01E-070.9999999
NCOA3chr2046130763+EYA2chr2045801354+2.99E-131
NCOA3chr2046130763+EYA2chr2045771697+1.43E-081
NCOA3chr2046130763+EYA2chr2045801354+2.99E-131
NCOA3chr2046130763+EYA2chr2045618639+3.16E-111

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions. We integrated a total of 44 different types of human genomic feature loci information across five big categories including virus integration sites, repeats, structural variants, chromatin states, and gene expression regulation. More details are in help page.
genomic feature

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions that are ovelapped with the top 1% feature importance score regions. More details are in help page.
genomic feature of top 1%

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Fusion Protein Features for NCOA3-EYA2


check button Four levels of functional features of fusion genes
Go to FGviewer search page for the most frequent breakpoint (https://ccsmweb.uth.edu/FGviewer/chr20:46271128/chr20:45700824)
- FGviewer provides the online visualization of the retention search of the protein functional features across DNA, RNA, protein, and pathological levels.
- How to search
1. Put your fusion gene symbol.
2. Press the tab key until there will be shown the breakpoint information filled.
4. Go down and press 'Search' tab twice.
4. Go down to have the hyperlink of the search result.
5. Click the hyperlink.
6. See the FGviewer result for your fusion gene.
FGviewer

check buttonMain function of each fusion partner protein. (from UniProt)
HgeneTgene
NCOA3

Q9Y6Q9

EYA2

O00167

FUNCTION: Nuclear receptor coactivator that directly binds nuclear receptors and stimulates the transcriptional activities in a hormone-dependent fashion. Plays a central role in creating a multisubunit coactivator complex, which probably acts via remodeling of chromatin. Involved in the coactivation of different nuclear receptors, such as for steroids (GR and ER), retinoids (RARs and RXRs), thyroid hormone (TRs), vitamin D3 (VDR) and prostanoids (PPARs). Displays histone acetyltransferase activity. Also involved in the coactivation of the NF-kappa-B pathway via its interaction with the NFKB1 subunit.FUNCTION: Functions both as protein phosphatase and as transcriptional coactivator for SIX1, and probably also for SIX2, SIX4 and SIX5 (PubMed:12500905, PubMed:23435380). Tyrosine phosphatase that dephosphorylates 'Tyr-142' of histone H2AX (H2AXY142ph) and promotes efficient DNA repair via the recruitment of DNA repair complexes containing MDC1. 'Tyr-142' phosphorylation of histone H2AX plays a central role in DNA repair and acts as a mark that distinguishes between apoptotic and repair responses to genotoxic stress (PubMed:19351884). Its function as histone phosphatase may contribute to its function in transcription regulation during organogenesis. Plays an important role in hypaxial muscle development together with SIX1 and DACH2; in this it is functionally redundant with EYA1 (PubMed:12500905). {ECO:0000269|PubMed:12500905, ECO:0000269|PubMed:19351884, ECO:0000269|PubMed:21706047, ECO:0000269|PubMed:23435380}.

check buttonRetention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at

download page


* Minus value of BPloci means that the break pointn is located before the CDS.
- In-frame and retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneNCOA3chr20:46280020chr20:45717877ENST00000371997+20231248_127813061416.0Compositional biasNote=Poly-Gln
HgeneNCOA3chr20:46280020chr20:45717877ENST00000371997+2023505_67113061416.0Compositional biasNote=Ser-rich
HgeneNCOA3chr20:46280020chr20:45717877ENST00000371997+2023976_98013061416.0Compositional biasNote=Poly-Gln
HgeneNCOA3chr20:46280020chr20:45717877ENST00000371998+20231248_127813151425.0Compositional biasNote=Poly-Gln
HgeneNCOA3chr20:46280020chr20:45717877ENST00000371998+2023505_67113151425.0Compositional biasNote=Ser-rich
HgeneNCOA3chr20:46280020chr20:45717877ENST00000371998+2023976_98013151425.0Compositional biasNote=Poly-Gln
HgeneNCOA3chr20:46280020chr20:45717877ENST00000372004+20231248_127813111421.0Compositional biasNote=Poly-Gln
HgeneNCOA3chr20:46280020chr20:45717877ENST00000372004+2023505_67113111421.0Compositional biasNote=Ser-rich
HgeneNCOA3chr20:46280020chr20:45717877ENST00000372004+2023976_98013111421.0Compositional biasNote=Poly-Gln
HgeneNCOA3chr20:46280020chr20:45717877ENST00000371997+2023110_18013061416.0DomainPAS
HgeneNCOA3chr20:46280020chr20:45717877ENST00000371997+202325_8213061416.0DomainbHLH
HgeneNCOA3chr20:46280020chr20:45717877ENST00000371998+2023110_18013151425.0DomainPAS
HgeneNCOA3chr20:46280020chr20:45717877ENST00000371998+202325_8213151425.0DomainbHLH
HgeneNCOA3chr20:46280020chr20:45717877ENST00000372004+2023110_18013111421.0DomainPAS
HgeneNCOA3chr20:46280020chr20:45717877ENST00000372004+202325_8213111421.0DomainbHLH
HgeneNCOA3chr20:46280020chr20:45717877ENST00000371997+20231057_106113061416.0MotifNote=LXXLL motif 3
HgeneNCOA3chr20:46280020chr20:45717877ENST00000371997+2023685_68913061416.0MotifNote=LXXLL motif 1
HgeneNCOA3chr20:46280020chr20:45717877ENST00000371997+2023738_74213061416.0MotifNote=LXXLL motif 2
HgeneNCOA3chr20:46280020chr20:45717877ENST00000371998+20231057_106113151425.0MotifNote=LXXLL motif 3
HgeneNCOA3chr20:46280020chr20:45717877ENST00000371998+2023685_68913151425.0MotifNote=LXXLL motif 1
HgeneNCOA3chr20:46280020chr20:45717877ENST00000371998+2023738_74213151425.0MotifNote=LXXLL motif 2
HgeneNCOA3chr20:46280020chr20:45717877ENST00000372004+20231057_106113111421.0MotifNote=LXXLL motif 3
HgeneNCOA3chr20:46280020chr20:45717877ENST00000372004+2023685_68913111421.0MotifNote=LXXLL motif 1
HgeneNCOA3chr20:46280020chr20:45717877ENST00000372004+2023738_74213111421.0MotifNote=LXXLL motif 2
HgeneNCOA3chr20:46280020chr20:45717877ENST00000371997+20231097_130413061416.0RegionNote=Acetyltransferase
HgeneNCOA3chr20:46280020chr20:45717877ENST00000371998+20231097_130413151425.0RegionNote=Acetyltransferase
HgeneNCOA3chr20:46280020chr20:45717877ENST00000372004+20231097_130413111421.0RegionNote=Acetyltransferase

- In-frame and not-retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneNCOA3chr20:46280020chr20:45717877ENST00000371997+20231392_141713061416.0Compositional biasNote=Met-rich
HgeneNCOA3chr20:46280020chr20:45717877ENST00000371998+20231392_141713151425.0Compositional biasNote=Met-rich
HgeneNCOA3chr20:46280020chr20:45717877ENST00000372004+20231392_141713111421.0Compositional biasNote=Met-rich


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Fusion Gene Sequence for NCOA3-EYA2


check button For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. To have fusion amino acid sequence, we ran ORFfinder and chose the longest ORF among the all predicted ones.
>57735_57735_1_NCOA3-EYA2_NCOA3_chr20_46280020_ENST00000341724_EYA2_chr20_45717877_ENST00000327619_length(transcript)=5652nt_BP=3985nt
ATATCCCAGTGGCCCCCGTGCGGCGACTTTAGCTGCTGCTGTCTCAGCCGCTCCACAGCGACGGCAGCGGCTGCGGCTTAGTCGGTGGCG
GCCGGCGGCGGCTGCGGGCTGAGCGGCGAGTTTCCGATTTAAAGCTGAGCTGCGAGGAAAATGGCGGCGGGAGGATCAAAATACTTGCTG
GATGGTGGACTCAGAGACCAATAAAAATAAACTGCTTGAACATCCTTTGACTGGTTAGCCAGTTGCTGATGTATATTCAAGATGAGTGGA
TTAGGAGAAAACTTGGATCCACTGGCCAGTGATTCACGAAAACGCAAATTGCCATGTGATACTCCAGGACAAGGTCTTACCTGCAGTGGT
GAAAAACGGAGACGGGAGCAGGAAAGTAAATATATTGAAGAATTGGCTGAGCTGATATCTGCCAATCTTAGTGATATTGACAATTTCAAT
GTCAAACCAGATAAATGTGCGATTTTAAAGGAAACAGTAAGACAGATACGTCAAATAAAAGAGCAAGGAAAAACTATTTCCAATGATGAT
GATGTTCAAAAAGCCGATGTATCTTCTACAGGGCAGGGAGTTATTGATAAAGACTCCTTAGGACCGCTTTTACTTCAGGCATTGGATGGT
TTCCTATTTGTGGTGAATCGAGACGGAAACATTGTATTTGTATCAGAAAATGTCACACAATACCTGCAATATAAGCAAGAGGACCTGGTT
AACACAAGTGTTTACAATATCTTACATGAAGAAGACAGAAAGGATTTTCTTAAGAATTTACCAAAATCTACAGTTAATGGAGTTTCCTGG
ACAAATGAGACCCAAAGACAAAAAAGCCATACATTTAATTGCCGTATGTTGATGAAAACACCACATGATATTCTGGAAGACATAAACGCC
AGTCCTGAAATGCGCCAGAGATATGAAACAATGCAGTGCTTTGCCCTGTCTCAGCCACGAGCTATGATGGAGGAAGGGGAAGATTTGCAA
TCTTGTATGATCTGTGTGGCACGCCGCATTACTACAGGAGAAAGAACATTTCCATCAAACCCTGAGAGCTTTATTACCAGACATGATCTT
TCAGGAAAGGTTGTCAATATAGATACAAATTCACTGAGATCCTCCATGAGGCCTGGCTTTGAAGATATAATCCGAAGGTGTATTCAGAGA
TTTTTTAGTCTAAATGATGGGCAGTCATGGTCCCAGAAACGTCACTATCAAGAAGTTACCAGTGATGGGATATTTTCCCCAACAGCTTAT
CTTAATGGCCATGCAGAAACCCCAGTATATCGATTCTCGTTGGCTGATGGAACTATAGTGACTGCACAGACAAAAAGCAAACTCTTCCGA
AATCCTGTAACAAATGATCGACATGGCTTTGTCTCAACCCACTTCCTTCAGAGAGAACAGAATGGATATAGACCAAACCCAAATCCTGTT
GGACAAGGGATTAGACCACCTATGGCTGGATGCAACAGTTCGGTAGGCGGCATGAGTATGTCGCCAAACCAAGGCTTACAGATGCCGAGC
AGCAGGGCCTATGGCTTGGCAGACCCTAGCACCACAGGGCAGATGAGTGGAGCTAGGTATGGGGGTTCCAGTAACATAGCTTCATTGACC
CCTGGGCCAGGCATGCAATCACCATCTTCCTACCAGAACAACAACTATGGGCTCAACATGAGTAGCCCCCCACATGGGAGTCCTGGTCTT
GCCCCAAACCAGCAGAATATCATGATTTCTCCTCGTAATCGTGGGAGTCCAAAGATAGCCTCACATCAGTTTTCTCCTGTTGCAGGTGTG
CACTCTCCCATGGCATCTTCTGGCAATACTGGGAACCACAGCTTTTCCAGCAGCTCTCTCAGTGCCCTGCAAGCCATCAGTGAAGGTGTG
GGGACTTCCCTTTTATCTACTCTGTCATCACCAGGCCCCAAATTGGATAACTCTCCCAATATGAATATTACCCAACCAAGTAAAGTAAGC
AATCAGGATTCCAAGAGTCCTCTGGGCTTTTATTGCGACCAAAATCCAGTGGAGAGTTCAATGTGTCAGTCAAATAGCAGAGATCACCTC
AGTGACAAAGAAAGTAAGGAGAGCAGTGTTGAGGGGGCAGAGAATCAAAGGGGTCCTTTGGAAAGCAAAGGTCATAAAAAATTACTGCAG
TTACTTACCTGTTCTTCTGATGACCGGGGTCATTCCTCCTTGACCAACTCCCCCCTAGATTCAAGTTGTAAAGAATCTTCTGTTAGTGTC
ACCAGCCCCTCTGGAGTCTCCTCCTCTACATCTGGAGGAGTATCCTCTACATCCAATATGCATGGGTCACTGTTACAAGAGAAGCACCGG
ATTTTGCACAAGTTGCTGCAGAATGGGAATTCACCAGCTGAGGTAGCCAAGATTACTGCAGAAGCCACTGGGAAAGACACCAGCAGTATA
ACTTCTTGTGGGGACGGAAATGTTGTCAAGCAGGAGCAGCTAAGTCCTAAGAAGAAGGAGAATAATGCACTTCTTAGATACCTGCTGGAC
AGGGATGATCCTAGTGATGCACTCTCTAAAGAACTACAGCCCCAAGTGGAAGGAGTGGATAATAAAATGAGTCAGTGCACCAGCTCCACC
ATTCCTAGCTCAAGTCAAGAGAAAGACCCTAAAATTAAGACAGAGACAAGTGAAGAGGGATCTGGAGACTTGGATAATCTAGATGCTATT
CTTGGTGATCTGACTAGTTCTGACTTTTACAATAATTCCATATCCTCAAATGGTAGTCATCTGGGGACTAAGCAACAGGTGTTTCAAGGA
ACTAATTCTCTGGGAGACTGGGGCTTACCAAACTCAAAGGCCGGCAGAATGGAACCTATGAATTCAAACTCCATGGGAAGACCAGGAGGA
GATTATAATACTTCTTTACCCAGACCTGCACTGGGTGGCTCTATTCCCACATTGCCTCTTCGGTCTAATAGCATACCAGGTGCGAGACCA
GTATTGCAACAGCAGCAGCAGATGCTTCAAATGAGGCCTGGTGAAATCCCCATGGGAATGGGGGCTAATCCCTATGGCCAAGCAGCAGCA
TCTAACCAACTGGGTTCCTGGCCCGATGGCATGTTGTCCATGGAACAAGTTTCTCATGGCACTCAAAATAGGCCTCTTCTTAGGAATTCC
CTGGATGATCTTGTTGGGCCACCTTCCAACCTGGAAGGCCAGAGTGACGAAAGAGCATTATTGGACCAGCTGCACACTCTTCTCAGCAAC
ACAGATGCCACAGGCCTGGAAGAAATTGACAGAGCTTTGGGCATTCCTGAACTTGTCAATCAGGGACAGGCATTAGAGCCCAAACAGGAT
GCTTTCCAAGGCCAAGAAGCAGCAGTAATGATGGATCAGAAGGCAGGATTATATGGACAGACATACCCAGCACAGGGGCCTCCAATGCAA
GGAGGCTTTCATCTTCAGGGACAATCACCATCTTTTAACTCTATGATGAATCAGATGAACCAGCAAGGCAATTTTCCTCTCCAAGGAATG
CACCCACGAGCCAACATCATGAGACCCCGGACAAACACCCCCAAGCAACTTAGAATGCAGCTTCAGCAGAGGCTGCAGGGCCAGCAGTTT
TTGAATCAGAGCCGACAGGCACTTGAATTGAAAATGGAAAACCCTACTGCTGGTGGTGCTGCGGTGATGAGGCCTATGATGCAGCCCCAG
CAGGGTTTTCTTAATGCTCAAATGGTCGCCCAACGCAGCAGAGAGCTGCTAAGTCATCACTTCCGACAACAGAGGGTGGCTATGATGATG
CAGCAGCAGCAGCAGCAGCAACAGCAGCAGCAGCAGCAGCAGCAGCAGCAACAGCAACAGCAACAGCAACAGCAGCAACAGCAGCAAACC
CAGGCCTTCAGCCCACCTCCTAATGTGACTGCTTCCCCCAGCATGGATGGGCTTTTGGCAGGACCCACAATGCCACAAGCTCCTCCGCAA
CAGTTTCCATATCAACCAAATTATGGTGAATACAACACACACAATGGACCTTCCACACCAGCGAAAGAGGGAGACACAGACAGGCCGCAC
CGGGCCTCCGACGGGAAGCTCCGAGGCCGGTCTAAGAGGAGCAGTGACCCGTCCCCGGCAGGGGACAATGAGATTGAGCGTGTGTTCGTG
TGGGACTTGGATGAGACAATAATTATTTTTCACTCCTTACTCACGGGGACATTTGCATCCAGATACGGGAAGGACACCACGACGTCCGTG
CGCATTGGCCTTATGATGGAAGAGATGATCTTCAACCTTGCAGATACACATCTGTTCTTCAATGACCTGGAGGATTGTGACCAGATCCAC
GTTGATGACGTCTCATCAGATGACAATGGCCAAGATTTAAGCACATACAACTTCTCCGCTGACGGCTTCCACAGTTCGGCCCCAGGAGCC
AACCTGTGCCTGGGCTCTGGCGTGCACGGCGGCGTGGACTGGATGAGGAAGCTGGCCTTCCGCTACCGGCGGGTGAAGGAGATGTACAAT
ACCTACAAGAACAACGTTGGTGGGTTGATAGGCACTCCCAAAAGGGAGACCTGGCTACAGCTCCGAGCTGAGCTGGAAGCTCTCACAGAC
CTCTGGCTGACCCACTCCCTGAAGGCACTAAACCTCATCAACTCCCGGCCCAACTGTGTCAATGTGCTGGTCACCACCACTCAACTAATT
CCTGCCCTGGCCAAAGTCCTGCTATATGGCCTGGGGTCTGTGTTTCCTATTGAGAACATCTACAGTGCAACCAAGACAGGGAAGGAGAGC
TGCTTCGAGAGGATAATGCAGAGATTCGGCAGAAAAGCTGTCTACGTGGTGATCGGTGATGGTGTGGAAGAGGAGCAAGGAGCGAAAAAG
CACAACATGCCTTTCTGGCGGATATCCTGCCACGCAGACCTGGAGGCACTGAGGCACGCCCTGGAGCTGGAGTATTTATAGCAGGATCAG
CAGCATCTCCACCTGCCATCTCACCCTCAGACCCCCTCGCCTTCCCCACCTCCCCACCGAGAACTCCAGAGACCCAGATGTTGGACACCA
GGAAGGGGCCCCACAGCCGAGACGACGTGTCCAGTGACCATCTCAGAAGCCGTCCATCAGTCCAAATGGGGGTTCTGAGAAGGAAAGTAC
CCAACATTGGCTTCGGAGTATTTGACTTTGGGGAAAAGGGCTGGCTCGGAGTCTAGACTCTTCTGTAAGACTCACAGAACAAAAGCAAGG
AATTGCTGATTTGGGGGGTGCCTGGTGATGAGGAGGGGATGGGTTTGTCTTGTCTTCTTTTTAATTTATGGACTAGTCTCATTACTCCGG
AATTATGCTCTTGTACCTGTGTGGCTGGGTTTCTTAGTCGTTGGTTTGGTTTGGTTTTTTGAACTGGTATGTGGGGTGGTTCACAGTTCT
AATGTAAGCACTCTATTCTCCAAGTTGTGCTTTGTGGGGACAATCATTCTTTGAACATTAGAGAGGAAGGCAGTTCAAGCTGTTGAAAAG
ACTATTGCTTATTTTTGTTTTTAAAGACCTACTTGACGTCATGTGGACAGTGCACGTGCCTTACGCTACATCTTGTTTTCTAGGAAGAGG

>57735_57735_1_NCOA3-EYA2_NCOA3_chr20_46280020_ENST00000341724_EYA2_chr20_45717877_ENST00000327619_length(amino acids)=1559AA_BP=1241
MSGLGENLDPLASDSRKRKLPCDTPGQGLTCSGEKRRREQESKYIEELAELISANLSDIDNFNVKPDKCAILKETVRQIRQIKEQGKTIS
NDDDVQKADVSSTGQGVIDKDSLGPLLLQALDGFLFVVNRDGNIVFVSENVTQYLQYKQEDLVNTSVYNILHEEDRKDFLKNLPKSTVNG
VSWTNETQRQKSHTFNCRMLMKTPHDILEDINASPEMRQRYETMQCFALSQPRAMMEEGEDLQSCMICVARRITTGERTFPSNPESFITR
HDLSGKVVNIDTNSLRSSMRPGFEDIIRRCIQRFFSLNDGQSWSQKRHYQEVTSDGIFSPTAYLNGHAETPVYRFSLADGTIVTAQTKSK
LFRNPVTNDRHGFVSTHFLQREQNGYRPNPNPVGQGIRPPMAGCNSSVGGMSMSPNQGLQMPSSRAYGLADPSTTGQMSGARYGGSSNIA
SLTPGPGMQSPSSYQNNNYGLNMSSPPHGSPGLAPNQQNIMISPRNRGSPKIASHQFSPVAGVHSPMASSGNTGNHSFSSSSLSALQAIS
EGVGTSLLSTLSSPGPKLDNSPNMNITQPSKVSNQDSKSPLGFYCDQNPVESSMCQSNSRDHLSDKESKESSVEGAENQRGPLESKGHKK
LLQLLTCSSDDRGHSSLTNSPLDSSCKESSVSVTSPSGVSSSTSGGVSSTSNMHGSLLQEKHRILHKLLQNGNSPAEVAKITAEATGKDT
SSITSCGDGNVVKQEQLSPKKKENNALLRYLLDRDDPSDALSKELQPQVEGVDNKMSQCTSSTIPSSSQEKDPKIKTETSEEGSGDLDNL
DAILGDLTSSDFYNNSISSNGSHLGTKQQVFQGTNSLGDWGLPNSKAGRMEPMNSNSMGRPGGDYNTSLPRPALGGSIPTLPLRSNSIPG
ARPVLQQQQQMLQMRPGEIPMGMGANPYGQAAASNQLGSWPDGMLSMEQVSHGTQNRPLLRNSLDDLVGPPSNLEGQSDERALLDQLHTL
LSNTDATGLEEIDRALGIPELVNQGQALEPKQDAFQGQEAAVMMDQKAGLYGQTYPAQGPPMQGGFHLQGQSPSFNSMMNQMNQQGNFPL
QGMHPRANIMRPRTNTPKQLRMQLQQRLQGQQFLNQSRQALELKMENPTAGGAAVMRPMMQPQQGFLNAQMVAQRSRELLSHHFRQQRVA
MMMQQQQQQQQQQQQQQQQQQQQQQQQQQQQQTQAFSPPPNVTASPSMDGLLAGPTMPQAPPQQFPYQPNYGEYNTHNGPSTPAKEGDTD
RPHRASDGKLRGRSKRSSDPSPAGDNEIERVFVWDLDETIIIFHSLLTGTFASRYGKDTTTSVRIGLMMEEMIFNLADTHLFFNDLEDCD
QIHVDDVSSDDNGQDLSTYNFSADGFHSSAPGANLCLGSGVHGGVDWMRKLAFRYRRVKEMYNTYKNNVGGLIGTPKRETWLQLRAELEA
LTDLWLTHSLKALNLINSRPNCVNVLVTTTQLIPALAKVLLYGLGSVFPIENIYSATKTGKESCFERIMQRFGRKAVYVVIGDGVEEEQG

--------------------------------------------------------------
>57735_57735_2_NCOA3-EYA2_NCOA3_chr20_46280020_ENST00000341724_EYA2_chr20_45717877_ENST00000357410_length(transcript)=5415nt_BP=3985nt
ATATCCCAGTGGCCCCCGTGCGGCGACTTTAGCTGCTGCTGTCTCAGCCGCTCCACAGCGACGGCAGCGGCTGCGGCTTAGTCGGTGGCG
GCCGGCGGCGGCTGCGGGCTGAGCGGCGAGTTTCCGATTTAAAGCTGAGCTGCGAGGAAAATGGCGGCGGGAGGATCAAAATACTTGCTG
GATGGTGGACTCAGAGACCAATAAAAATAAACTGCTTGAACATCCTTTGACTGGTTAGCCAGTTGCTGATGTATATTCAAGATGAGTGGA
TTAGGAGAAAACTTGGATCCACTGGCCAGTGATTCACGAAAACGCAAATTGCCATGTGATACTCCAGGACAAGGTCTTACCTGCAGTGGT
GAAAAACGGAGACGGGAGCAGGAAAGTAAATATATTGAAGAATTGGCTGAGCTGATATCTGCCAATCTTAGTGATATTGACAATTTCAAT
GTCAAACCAGATAAATGTGCGATTTTAAAGGAAACAGTAAGACAGATACGTCAAATAAAAGAGCAAGGAAAAACTATTTCCAATGATGAT
GATGTTCAAAAAGCCGATGTATCTTCTACAGGGCAGGGAGTTATTGATAAAGACTCCTTAGGACCGCTTTTACTTCAGGCATTGGATGGT
TTCCTATTTGTGGTGAATCGAGACGGAAACATTGTATTTGTATCAGAAAATGTCACACAATACCTGCAATATAAGCAAGAGGACCTGGTT
AACACAAGTGTTTACAATATCTTACATGAAGAAGACAGAAAGGATTTTCTTAAGAATTTACCAAAATCTACAGTTAATGGAGTTTCCTGG
ACAAATGAGACCCAAAGACAAAAAAGCCATACATTTAATTGCCGTATGTTGATGAAAACACCACATGATATTCTGGAAGACATAAACGCC
AGTCCTGAAATGCGCCAGAGATATGAAACAATGCAGTGCTTTGCCCTGTCTCAGCCACGAGCTATGATGGAGGAAGGGGAAGATTTGCAA
TCTTGTATGATCTGTGTGGCACGCCGCATTACTACAGGAGAAAGAACATTTCCATCAAACCCTGAGAGCTTTATTACCAGACATGATCTT
TCAGGAAAGGTTGTCAATATAGATACAAATTCACTGAGATCCTCCATGAGGCCTGGCTTTGAAGATATAATCCGAAGGTGTATTCAGAGA
TTTTTTAGTCTAAATGATGGGCAGTCATGGTCCCAGAAACGTCACTATCAAGAAGTTACCAGTGATGGGATATTTTCCCCAACAGCTTAT
CTTAATGGCCATGCAGAAACCCCAGTATATCGATTCTCGTTGGCTGATGGAACTATAGTGACTGCACAGACAAAAAGCAAACTCTTCCGA
AATCCTGTAACAAATGATCGACATGGCTTTGTCTCAACCCACTTCCTTCAGAGAGAACAGAATGGATATAGACCAAACCCAAATCCTGTT
GGACAAGGGATTAGACCACCTATGGCTGGATGCAACAGTTCGGTAGGCGGCATGAGTATGTCGCCAAACCAAGGCTTACAGATGCCGAGC
AGCAGGGCCTATGGCTTGGCAGACCCTAGCACCACAGGGCAGATGAGTGGAGCTAGGTATGGGGGTTCCAGTAACATAGCTTCATTGACC
CCTGGGCCAGGCATGCAATCACCATCTTCCTACCAGAACAACAACTATGGGCTCAACATGAGTAGCCCCCCACATGGGAGTCCTGGTCTT
GCCCCAAACCAGCAGAATATCATGATTTCTCCTCGTAATCGTGGGAGTCCAAAGATAGCCTCACATCAGTTTTCTCCTGTTGCAGGTGTG
CACTCTCCCATGGCATCTTCTGGCAATACTGGGAACCACAGCTTTTCCAGCAGCTCTCTCAGTGCCCTGCAAGCCATCAGTGAAGGTGTG
GGGACTTCCCTTTTATCTACTCTGTCATCACCAGGCCCCAAATTGGATAACTCTCCCAATATGAATATTACCCAACCAAGTAAAGTAAGC
AATCAGGATTCCAAGAGTCCTCTGGGCTTTTATTGCGACCAAAATCCAGTGGAGAGTTCAATGTGTCAGTCAAATAGCAGAGATCACCTC
AGTGACAAAGAAAGTAAGGAGAGCAGTGTTGAGGGGGCAGAGAATCAAAGGGGTCCTTTGGAAAGCAAAGGTCATAAAAAATTACTGCAG
TTACTTACCTGTTCTTCTGATGACCGGGGTCATTCCTCCTTGACCAACTCCCCCCTAGATTCAAGTTGTAAAGAATCTTCTGTTAGTGTC
ACCAGCCCCTCTGGAGTCTCCTCCTCTACATCTGGAGGAGTATCCTCTACATCCAATATGCATGGGTCACTGTTACAAGAGAAGCACCGG
ATTTTGCACAAGTTGCTGCAGAATGGGAATTCACCAGCTGAGGTAGCCAAGATTACTGCAGAAGCCACTGGGAAAGACACCAGCAGTATA
ACTTCTTGTGGGGACGGAAATGTTGTCAAGCAGGAGCAGCTAAGTCCTAAGAAGAAGGAGAATAATGCACTTCTTAGATACCTGCTGGAC
AGGGATGATCCTAGTGATGCACTCTCTAAAGAACTACAGCCCCAAGTGGAAGGAGTGGATAATAAAATGAGTCAGTGCACCAGCTCCACC
ATTCCTAGCTCAAGTCAAGAGAAAGACCCTAAAATTAAGACAGAGACAAGTGAAGAGGGATCTGGAGACTTGGATAATCTAGATGCTATT
CTTGGTGATCTGACTAGTTCTGACTTTTACAATAATTCCATATCCTCAAATGGTAGTCATCTGGGGACTAAGCAACAGGTGTTTCAAGGA
ACTAATTCTCTGGGAGACTGGGGCTTACCAAACTCAAAGGCCGGCAGAATGGAACCTATGAATTCAAACTCCATGGGAAGACCAGGAGGA
GATTATAATACTTCTTTACCCAGACCTGCACTGGGTGGCTCTATTCCCACATTGCCTCTTCGGTCTAATAGCATACCAGGTGCGAGACCA
GTATTGCAACAGCAGCAGCAGATGCTTCAAATGAGGCCTGGTGAAATCCCCATGGGAATGGGGGCTAATCCCTATGGCCAAGCAGCAGCA
TCTAACCAACTGGGTTCCTGGCCCGATGGCATGTTGTCCATGGAACAAGTTTCTCATGGCACTCAAAATAGGCCTCTTCTTAGGAATTCC
CTGGATGATCTTGTTGGGCCACCTTCCAACCTGGAAGGCCAGAGTGACGAAAGAGCATTATTGGACCAGCTGCACACTCTTCTCAGCAAC
ACAGATGCCACAGGCCTGGAAGAAATTGACAGAGCTTTGGGCATTCCTGAACTTGTCAATCAGGGACAGGCATTAGAGCCCAAACAGGAT
GCTTTCCAAGGCCAAGAAGCAGCAGTAATGATGGATCAGAAGGCAGGATTATATGGACAGACATACCCAGCACAGGGGCCTCCAATGCAA
GGAGGCTTTCATCTTCAGGGACAATCACCATCTTTTAACTCTATGATGAATCAGATGAACCAGCAAGGCAATTTTCCTCTCCAAGGAATG
CACCCACGAGCCAACATCATGAGACCCCGGACAAACACCCCCAAGCAACTTAGAATGCAGCTTCAGCAGAGGCTGCAGGGCCAGCAGTTT
TTGAATCAGAGCCGACAGGCACTTGAATTGAAAATGGAAAACCCTACTGCTGGTGGTGCTGCGGTGATGAGGCCTATGATGCAGCCCCAG
CAGGGTTTTCTTAATGCTCAAATGGTCGCCCAACGCAGCAGAGAGCTGCTAAGTCATCACTTCCGACAACAGAGGGTGGCTATGATGATG
CAGCAGCAGCAGCAGCAGCAACAGCAGCAGCAGCAGCAGCAGCAGCAGCAACAGCAACAGCAACAGCAACAGCAGCAACAGCAGCAAACC
CAGGCCTTCAGCCCACCTCCTAATGTGACTGCTTCCCCCAGCATGGATGGGCTTTTGGCAGGACCCACAATGCCACAAGCTCCTCCGCAA
CAGTTTCCATATCAACCAAATTATGGTGAATACAACACACACAATGGACCTTCCACACCAGCGAAAGAGGGAGACACAGACAGGCCGCAC
CGGGCCTCCGACGGGAAGCTCCGAGGCCGGTCTAAGAGGAGCAGTGACCCGTCCCCGGCAGGGGACAATGAGATTGAGCGTGTGTTCGTG
TGGGACTTGGATGAGACAATAATTATTTTTCACTCCTTACTCACGGGGACATTTGCATCCAGATACGGGAAGGACACCACGACGTCCGTG
CGCATTGGCCTTATGATGGAAGAGATGATCTTCAACCTTGCAGATACACATCTGTTCTTCAATGACCTGGAGGATTGTGACCAGATCCAC
GTTGATGACGTCTCATCAGATGACAATGGCCAAGATTTAAGCACATACAACTTCTCCGCTGACGGCTTCCACAGTTCGGCCCCAGGAGCC
AACCTGTGCCTGGGCTCTGGCGTGCACGGCGGCGTGGACTGGATGAGGAAGCTGGCCTTCCGCTACCGGCGGGTGAAGGAGATGTACAAT
ACCTACAAGAACAACGTTGGTGGGAAGGAGAGCTGCTTCGAGAGGATAATGCAGAGATTCGGCAGAAAAGCTGTCTACGTGGTGATCGGT
GATGGTGTGGAAGAGGAGCAAGGAGCGAAAAAGCACAACATGCCTTTCTGGCGGATATCCTGCCACGCAGACCTGGAGGCACTGAGGCAC
GCCCTGGAGCTGGAGTATTTATAGCAGGATCAGCAGCATCTCCACCTGCCATCTCACCCTCAGACCCCCTCGCCTTCCCCACCTCCCCAC
CGAGAACTCCAGAGACCCAGATGTTGGACACCAGGAAGGGGCCCCACAGCCGAGACGACGTGTCCAGTGACCATCTCAGAAGCCGTCCAT
CAGTCCAAATGGGGGTTCTGAGAAGGAAAGTACCCAACATTGGCTTCGGAGTATTTGACTTTGGGGAAAAGGGCTGGCTCGGAGTCTAGA
CTCTTCTGTAAGACTCACAGAACAAAAGCAAGGAATTGCTGATTTGGGGGGTGCCTGGTGATGAGGAGGGGATGGGTTTGTCTTGTCTTC
TTTTTAATTTATGGACTAGTCTCATTACTCCGGAATTATGCTCTTGTACCTGTGTGGCTGGGTTTCTTAGTCGTTGGTTTGGTTTGGTTT
TTTGAACTGGTATGTGGGGTGGTTCACAGTTCTAATGTAAGCACTCTATTCTCCAAGTTGTGCTTTGTGGGGACAATCATTCTTTGAACA
TTAGAGAGGAAGGCAGTTCAAGCTGTTGAAAAGACTATTGCTTATTTTTGTTTTTAAAGACCTACTTGACGTCATGTGGACAGTGCACGT
GCCTTACGCTACATCTTGTTTTCTAGGAAGAGGGGGATGCTGGGAAGGAATGGGTGCTTTGTGATGGATAAAAGGCATTAAATAAAACCA

>57735_57735_2_NCOA3-EYA2_NCOA3_chr20_46280020_ENST00000341724_EYA2_chr20_45717877_ENST00000357410_length(amino acids)=1480AA_BP=1241
MSGLGENLDPLASDSRKRKLPCDTPGQGLTCSGEKRRREQESKYIEELAELISANLSDIDNFNVKPDKCAILKETVRQIRQIKEQGKTIS
NDDDVQKADVSSTGQGVIDKDSLGPLLLQALDGFLFVVNRDGNIVFVSENVTQYLQYKQEDLVNTSVYNILHEEDRKDFLKNLPKSTVNG
VSWTNETQRQKSHTFNCRMLMKTPHDILEDINASPEMRQRYETMQCFALSQPRAMMEEGEDLQSCMICVARRITTGERTFPSNPESFITR
HDLSGKVVNIDTNSLRSSMRPGFEDIIRRCIQRFFSLNDGQSWSQKRHYQEVTSDGIFSPTAYLNGHAETPVYRFSLADGTIVTAQTKSK
LFRNPVTNDRHGFVSTHFLQREQNGYRPNPNPVGQGIRPPMAGCNSSVGGMSMSPNQGLQMPSSRAYGLADPSTTGQMSGARYGGSSNIA
SLTPGPGMQSPSSYQNNNYGLNMSSPPHGSPGLAPNQQNIMISPRNRGSPKIASHQFSPVAGVHSPMASSGNTGNHSFSSSSLSALQAIS
EGVGTSLLSTLSSPGPKLDNSPNMNITQPSKVSNQDSKSPLGFYCDQNPVESSMCQSNSRDHLSDKESKESSVEGAENQRGPLESKGHKK
LLQLLTCSSDDRGHSSLTNSPLDSSCKESSVSVTSPSGVSSSTSGGVSSTSNMHGSLLQEKHRILHKLLQNGNSPAEVAKITAEATGKDT
SSITSCGDGNVVKQEQLSPKKKENNALLRYLLDRDDPSDALSKELQPQVEGVDNKMSQCTSSTIPSSSQEKDPKIKTETSEEGSGDLDNL
DAILGDLTSSDFYNNSISSNGSHLGTKQQVFQGTNSLGDWGLPNSKAGRMEPMNSNSMGRPGGDYNTSLPRPALGGSIPTLPLRSNSIPG
ARPVLQQQQQMLQMRPGEIPMGMGANPYGQAAASNQLGSWPDGMLSMEQVSHGTQNRPLLRNSLDDLVGPPSNLEGQSDERALLDQLHTL
LSNTDATGLEEIDRALGIPELVNQGQALEPKQDAFQGQEAAVMMDQKAGLYGQTYPAQGPPMQGGFHLQGQSPSFNSMMNQMNQQGNFPL
QGMHPRANIMRPRTNTPKQLRMQLQQRLQGQQFLNQSRQALELKMENPTAGGAAVMRPMMQPQQGFLNAQMVAQRSRELLSHHFRQQRVA
MMMQQQQQQQQQQQQQQQQQQQQQQQQQQQQQTQAFSPPPNVTASPSMDGLLAGPTMPQAPPQQFPYQPNYGEYNTHNGPSTPAKEGDTD
RPHRASDGKLRGRSKRSSDPSPAGDNEIERVFVWDLDETIIIFHSLLTGTFASRYGKDTTTSVRIGLMMEEMIFNLADTHLFFNDLEDCD
QIHVDDVSSDDNGQDLSTYNFSADGFHSSAPGANLCLGSGVHGGVDWMRKLAFRYRRVKEMYNTYKNNVGGKESCFERIMQRFGRKAVYV

--------------------------------------------------------------
>57735_57735_3_NCOA3-EYA2_NCOA3_chr20_46280020_ENST00000371997_EYA2_chr20_45717877_ENST00000327619_length(transcript)=5763nt_BP=4096nt
GTGGCGGCCGGCGGCGGCTGCGGGCTGAGCGGCGAGTTTCCGATTTAAAGCTGAGCTGCGAGGAAAATGGCGGCGGGAGGATCAAAATAC
TTGCTGGATGGTGGACTCAGAGACCAATAAAAATAAACTGCTTGAACATCCTTTGACTGGTTAGCCAGTTGCTGATGTATATTCAAGATG
AGTGGATTAGGAGAAAACTTGGATCCACTGGCCAGTGATTCACGAAAACGCAAATTGCCATGTGATACTCCAGGACAAGGTCTTACCTGC
AGTGGTGAAAAACGGAGACGGGAGCAGGAAAGTAAATATATTGAAGAATTGGCTGAGCTGATATCTGCCAATCTTAGTGATATTGACAAT
TTCAATGTCAAACCAGATAAATGTGCGATTTTAAAGGAAACAGTAAGACAGATACGTCAAATAAAAGAGCAAGGAAAAACTATTTCCAAT
GATGATGATGTTCAAAAAGCCGATGTATCTTCTACAGGGCAGGGAGTTATTGATAAAGACTCCTTAGGACCGCTTTTACTTCAGGCATTG
GATGGTTTCCTATTTGTGGTGAATCGAGACGGAAACATTGTATTTGTATCAGAAAATGTCACACAATACCTGCAATATAAGCAAGAGGAC
CTGGTTAACACAAGTGTTTACAATATCTTACATGAAGAAGACAGAAAGGATTTTCTTAAGAATTTACCAAAATCTACAGTTAATGGAGTT
TCCTGGACAAATGAGACCCAAAGACAAAAAAGCCATACATTTAATTGCCGTATGTTGATGAAAACACCACATGATATTCTGGAAGACATA
AACGCCAGTCCTGAAATGCGCCAGAGATATGAAACAATGCAGTGCTTTGCCCTGTCTCAGCCACGAGCTATGATGGAGGAAGGGGAAGAT
TTGCAATCTTGTATGATCTGTGTGGCACGCCGCATTACTACAGGAGAAAGAACATTTCCATCAAACCCTGAGAGCTTTATTACCAGACAT
GATCTTTCAGGAAAGGTTGTCAATATAGATACAAATTCACTGAGATCCTCCATGAGGCCTGGCTTTGAAGATATAATCCGAAGGTGTATT
CAGAGATTTTTTAGTCTAAATGATGGGCAGTCATGGTCCCAGAAACGTCACTATCAAGAAGTTACCAGTGATGGGATATTTTCCCCAACA
GCTTATCTTAATGGCCATGCAGAAACCCCAGTATATCGATTCTCGTTGGCTGATGGAACTATAGTGACTGCACAGACAAAAAGCAAACTC
TTCCGAAATCCTGTAACAAATGATCGACATGGCTTTGTCTCAACCCACTTCCTTCAGAGAGAACAGAATGGATATAGACCAAACCCAAAT
CCTGTTGGACAAGGGATTAGACCACCTATGGCTGGATGCAACAGTTCGGTAGGCGGCATGAGTATGTCGCCAAACCAAGGCTTACAGATG
CCGAGCAGCAGGGCCTATGGCTTGGCAGACCCTAGCACCACAGGGCAGATGAGTGGAGCTAGGTATGGGGGTTCCAGTAACATAGCTTCA
TTGACCCCTGGGCCAGGCATGCAATCACCATCTTCCTACCAGAACAACAACTATGGGCTCAACATGAGTAGCCCCCCACATGGGAGTCCT
GGTCTTGCCCCAAACCAGCAGAATATCATGATTTCTCCTCGTAATCGTGGGAGTCCAAAGATAGCCTCACATCAGTTTTCTCCTGTTGCA
GGTGTGCACTCTCCCATGGCATCTTCTGGCAATACTGGGAACCACAGCTTTTCCAGCAGCTCTCTCAGTGCCCTGCAAGCCATCAGTGAA
GGTGTGGGGACTTCCCTTTTATCTACTCTGTCATCACCAGGCCCCAAATTGGATAACTCTCCCAATATGAATATTACCCAACCAAGTAAA
GTAAGCAATCAGGATTCCAAGAGTCCTCTGGGCTTTTATTGCGACCAAAATCCAGTGGAGAGTTCAATGTGTCAGTCAAATAGCAGAGAT
CACCTCAGTGACAAAGAAAGTAAGGAGAGCAGTGTTGAGGGGGCAGAGAATCAAAGGGGTCCTTTGGAAAGCAAAGGTCATAAAAAATTA
CTGCAGTTACTTACCTGTTCTTCTGATGACCGGGGTCATTCCTCCTTGACCAACTCCCCCCTAGATTCAAGTTGTAAAGAATCTTCTGTT
AGTGTCACCAGCCCCTCTGGAGTCTCCTCCTCTACATCTGGAGGAGTATCCTCTACATCCAATATGCATGGGTCACTGTTACAAGAGAAG
CACCGGATTTTGCACAAGTTGCTGCAGAATGGGAATTCACCAGCTGAGGTAGCCAAGATTACTGCAGAAGCCACTGGGAAAGACACCAGC
AGTATAACTTCTTGTGGGGACGGAAATGTTGTCAAGCAGGAGCAGCTAAGTCCTAAGAAGAAGGAGAATAATGCACTTCTTAGATACCTG
CTGGACAGGGATGATCCTAGTGATGCACTCTCTAAAGAACTACAGCCCCAAGTGGAAGGAGTGGATAATAAAATGAGTCAGTGCACCAGC
TCCACCATTCCTAGCTCAAGTCAAGAGAAAGACCCTAAAATTAAGACAGAGACAAGTGAAGAGGGATCTGGAGACTTGGATAATCTAGAT
GCTATTCTTGGTGATCTGACTAGTTCTGACTTTTACAATAATTCCATATCCTCAAATGGTAGTCATCTGGGGACTAAGCAACAGGTGTTT
CAAGGAACTAATTCTCTGGGTTTGAAAAGTTCACAGTCTGTGCAGTCTATTCGTCCTCCATATAACCGAGCAGTGTCTCTGGATAGCCCT
GTTTCTGTTGGCTCAAGTCCTCCAGTAAAAAATATCAGTGCTTTCCCCATGTTACCAAAGCAACCCATGTTGGGTGGGAATCCAAGAATG
ATGGATAGTCAGGAAAATTATGGCTCAAGTATGGGAGACTGGGGCTTACCAAACTCAAAGGCCGGCAGAATGGAACCTATGAATTCAAAC
TCCATGGGAAGACCAGGAGGAGATTATAATACTTCTTTACCCAGACCTGCACTGGGTGGCTCTATTCCCACATTGCCTCTTCGGTCTAAT
AGCATACCAGGTGCGAGACCAGTATTGCAACAGCAGCAGCAGATGCTTCAAATGAGGCCTGGTGAAATCCCCATGGGAATGGGGGCTAAT
CCCTATGGCCAAGCAGCAGCATCTAACCAACTGGGTTCCTGGCCCGATGGCATGTTGTCCATGGAACAAGTTTCTCATGGCACTCAAAAT
AGGCCTCTTCTTAGGAATTCCCTGGATGATCTTGTTGGGCCACCTTCCAACCTGGAAGGCCAGAGTGACGAAAGAGCATTATTGGACCAG
CTGCACACTCTTCTCAGCAACACAGATGCCACAGGCCTGGAAGAAATTGACAGAGCTTTGGGCATTCCTGAACTTGTCAATCAGGGACAG
GCATTAGAGCCCAAACAGGATGCTTTCCAAGGCCAAGAAGCAGCAGTAATGATGGATCAGAAGGCAGGATTATATGGACAGACATACCCA
GCACAGGGGCCTCCAATGCAAGGAGGCTTTCATCTTCAGGGACAATCACCATCTTTTAACTCTATGATGAATCAGATGAACCAGCAAGGC
AATTTTCCTCTCCAAGGAATGCACCCACGAGCCAACATCATGAGACCCCGGACAAACACCCCCAAGCAACTTAGAATGCAGCTTCAGCAG
AGGCTGCAGGGCCAGCAGTTTTTGAATCAGAGCCGACAGGCACTTGAATTGAAAATGGAAAACCCTACTGCTGGTGGTGCTGCGGTGATG
AGGCCTATGATGCAGCCCCAGCAGGGTTTTCTTAATGCTCAAATGGTCGCCCAACGCAGCAGAGAGCTGCTAAGTCATCACTTCCGACAA
CAGAGGGTGGCTATGATGATGCAGCAGCAGCAGCAGCAGCAACAGCAGCAGCAGCAGCAGCAGCAGCAGCAACAGCAACAGCAACAGCAA
CAGCAGCAACAGCAGCAAACCCAGGCCTTCAGCCCACCTCCTAATGTGACTGCTTCCCCCAGCATGGATGGGCTTTTGGCAGGACCCACA
ATGCCACAAGCTCCTCCGCAACAGTTTCCATATCAACCAAATTATGGTGAATACAACACACACAATGGACCTTCCACACCAGCGAAAGAG
GGAGACACAGACAGGCCGCACCGGGCCTCCGACGGGAAGCTCCGAGGCCGGTCTAAGAGGAGCAGTGACCCGTCCCCGGCAGGGGACAAT
GAGATTGAGCGTGTGTTCGTGTGGGACTTGGATGAGACAATAATTATTTTTCACTCCTTACTCACGGGGACATTTGCATCCAGATACGGG
AAGGACACCACGACGTCCGTGCGCATTGGCCTTATGATGGAAGAGATGATCTTCAACCTTGCAGATACACATCTGTTCTTCAATGACCTG
GAGGATTGTGACCAGATCCACGTTGATGACGTCTCATCAGATGACAATGGCCAAGATTTAAGCACATACAACTTCTCCGCTGACGGCTTC
CACAGTTCGGCCCCAGGAGCCAACCTGTGCCTGGGCTCTGGCGTGCACGGCGGCGTGGACTGGATGAGGAAGCTGGCCTTCCGCTACCGG
CGGGTGAAGGAGATGTACAATACCTACAAGAACAACGTTGGTGGGTTGATAGGCACTCCCAAAAGGGAGACCTGGCTACAGCTCCGAGCT
GAGCTGGAAGCTCTCACAGACCTCTGGCTGACCCACTCCCTGAAGGCACTAAACCTCATCAACTCCCGGCCCAACTGTGTCAATGTGCTG
GTCACCACCACTCAACTAATTCCTGCCCTGGCCAAAGTCCTGCTATATGGCCTGGGGTCTGTGTTTCCTATTGAGAACATCTACAGTGCA
ACCAAGACAGGGAAGGAGAGCTGCTTCGAGAGGATAATGCAGAGATTCGGCAGAAAAGCTGTCTACGTGGTGATCGGTGATGGTGTGGAA
GAGGAGCAAGGAGCGAAAAAGCACAACATGCCTTTCTGGCGGATATCCTGCCACGCAGACCTGGAGGCACTGAGGCACGCCCTGGAGCTG
GAGTATTTATAGCAGGATCAGCAGCATCTCCACCTGCCATCTCACCCTCAGACCCCCTCGCCTTCCCCACCTCCCCACCGAGAACTCCAG
AGACCCAGATGTTGGACACCAGGAAGGGGCCCCACAGCCGAGACGACGTGTCCAGTGACCATCTCAGAAGCCGTCCATCAGTCCAAATGG
GGGTTCTGAGAAGGAAAGTACCCAACATTGGCTTCGGAGTATTTGACTTTGGGGAAAAGGGCTGGCTCGGAGTCTAGACTCTTCTGTAAG
ACTCACAGAACAAAAGCAAGGAATTGCTGATTTGGGGGGTGCCTGGTGATGAGGAGGGGATGGGTTTGTCTTGTCTTCTTTTTAATTTAT
GGACTAGTCTCATTACTCCGGAATTATGCTCTTGTACCTGTGTGGCTGGGTTTCTTAGTCGTTGGTTTGGTTTGGTTTTTTGAACTGGTA
TGTGGGGTGGTTCACAGTTCTAATGTAAGCACTCTATTCTCCAAGTTGTGCTTTGTGGGGACAATCATTCTTTGAACATTAGAGAGGAAG
GCAGTTCAAGCTGTTGAAAAGACTATTGCTTATTTTTGTTTTTAAAGACCTACTTGACGTCATGTGGACAGTGCACGTGCCTTACGCTAC
ATCTTGTTTTCTAGGAAGAGGGGGATGCTGGGAAGGAATGGGTGCTTTGTGATGGATAAAAGGCATTAAATAAAACCACGTTTACATTTT

>57735_57735_3_NCOA3-EYA2_NCOA3_chr20_46280020_ENST00000371997_EYA2_chr20_45717877_ENST00000327619_length(amino acids)=1624AA_BP=1306
MSGLGENLDPLASDSRKRKLPCDTPGQGLTCSGEKRRREQESKYIEELAELISANLSDIDNFNVKPDKCAILKETVRQIRQIKEQGKTIS
NDDDVQKADVSSTGQGVIDKDSLGPLLLQALDGFLFVVNRDGNIVFVSENVTQYLQYKQEDLVNTSVYNILHEEDRKDFLKNLPKSTVNG
VSWTNETQRQKSHTFNCRMLMKTPHDILEDINASPEMRQRYETMQCFALSQPRAMMEEGEDLQSCMICVARRITTGERTFPSNPESFITR
HDLSGKVVNIDTNSLRSSMRPGFEDIIRRCIQRFFSLNDGQSWSQKRHYQEVTSDGIFSPTAYLNGHAETPVYRFSLADGTIVTAQTKSK
LFRNPVTNDRHGFVSTHFLQREQNGYRPNPNPVGQGIRPPMAGCNSSVGGMSMSPNQGLQMPSSRAYGLADPSTTGQMSGARYGGSSNIA
SLTPGPGMQSPSSYQNNNYGLNMSSPPHGSPGLAPNQQNIMISPRNRGSPKIASHQFSPVAGVHSPMASSGNTGNHSFSSSSLSALQAIS
EGVGTSLLSTLSSPGPKLDNSPNMNITQPSKVSNQDSKSPLGFYCDQNPVESSMCQSNSRDHLSDKESKESSVEGAENQRGPLESKGHKK
LLQLLTCSSDDRGHSSLTNSPLDSSCKESSVSVTSPSGVSSSTSGGVSSTSNMHGSLLQEKHRILHKLLQNGNSPAEVAKITAEATGKDT
SSITSCGDGNVVKQEQLSPKKKENNALLRYLLDRDDPSDALSKELQPQVEGVDNKMSQCTSSTIPSSSQEKDPKIKTETSEEGSGDLDNL
DAILGDLTSSDFYNNSISSNGSHLGTKQQVFQGTNSLGLKSSQSVQSIRPPYNRAVSLDSPVSVGSSPPVKNISAFPMLPKQPMLGGNPR
MMDSQENYGSSMGDWGLPNSKAGRMEPMNSNSMGRPGGDYNTSLPRPALGGSIPTLPLRSNSIPGARPVLQQQQQMLQMRPGEIPMGMGA
NPYGQAAASNQLGSWPDGMLSMEQVSHGTQNRPLLRNSLDDLVGPPSNLEGQSDERALLDQLHTLLSNTDATGLEEIDRALGIPELVNQG
QALEPKQDAFQGQEAAVMMDQKAGLYGQTYPAQGPPMQGGFHLQGQSPSFNSMMNQMNQQGNFPLQGMHPRANIMRPRTNTPKQLRMQLQ
QRLQGQQFLNQSRQALELKMENPTAGGAAVMRPMMQPQQGFLNAQMVAQRSRELLSHHFRQQRVAMMMQQQQQQQQQQQQQQQQQQQQQQ
QQQQQQQTQAFSPPPNVTASPSMDGLLAGPTMPQAPPQQFPYQPNYGEYNTHNGPSTPAKEGDTDRPHRASDGKLRGRSKRSSDPSPAGD
NEIERVFVWDLDETIIIFHSLLTGTFASRYGKDTTTSVRIGLMMEEMIFNLADTHLFFNDLEDCDQIHVDDVSSDDNGQDLSTYNFSADG
FHSSAPGANLCLGSGVHGGVDWMRKLAFRYRRVKEMYNTYKNNVGGLIGTPKRETWLQLRAELEALTDLWLTHSLKALNLINSRPNCVNV
LVTTTQLIPALAKVLLYGLGSVFPIENIYSATKTGKESCFERIMQRFGRKAVYVVIGDGVEEEQGAKKHNMPFWRISCHADLEALRHALE

--------------------------------------------------------------
>57735_57735_4_NCOA3-EYA2_NCOA3_chr20_46280020_ENST00000371997_EYA2_chr20_45717877_ENST00000357410_length(transcript)=5526nt_BP=4096nt
GTGGCGGCCGGCGGCGGCTGCGGGCTGAGCGGCGAGTTTCCGATTTAAAGCTGAGCTGCGAGGAAAATGGCGGCGGGAGGATCAAAATAC
TTGCTGGATGGTGGACTCAGAGACCAATAAAAATAAACTGCTTGAACATCCTTTGACTGGTTAGCCAGTTGCTGATGTATATTCAAGATG
AGTGGATTAGGAGAAAACTTGGATCCACTGGCCAGTGATTCACGAAAACGCAAATTGCCATGTGATACTCCAGGACAAGGTCTTACCTGC
AGTGGTGAAAAACGGAGACGGGAGCAGGAAAGTAAATATATTGAAGAATTGGCTGAGCTGATATCTGCCAATCTTAGTGATATTGACAAT
TTCAATGTCAAACCAGATAAATGTGCGATTTTAAAGGAAACAGTAAGACAGATACGTCAAATAAAAGAGCAAGGAAAAACTATTTCCAAT
GATGATGATGTTCAAAAAGCCGATGTATCTTCTACAGGGCAGGGAGTTATTGATAAAGACTCCTTAGGACCGCTTTTACTTCAGGCATTG
GATGGTTTCCTATTTGTGGTGAATCGAGACGGAAACATTGTATTTGTATCAGAAAATGTCACACAATACCTGCAATATAAGCAAGAGGAC
CTGGTTAACACAAGTGTTTACAATATCTTACATGAAGAAGACAGAAAGGATTTTCTTAAGAATTTACCAAAATCTACAGTTAATGGAGTT
TCCTGGACAAATGAGACCCAAAGACAAAAAAGCCATACATTTAATTGCCGTATGTTGATGAAAACACCACATGATATTCTGGAAGACATA
AACGCCAGTCCTGAAATGCGCCAGAGATATGAAACAATGCAGTGCTTTGCCCTGTCTCAGCCACGAGCTATGATGGAGGAAGGGGAAGAT
TTGCAATCTTGTATGATCTGTGTGGCACGCCGCATTACTACAGGAGAAAGAACATTTCCATCAAACCCTGAGAGCTTTATTACCAGACAT
GATCTTTCAGGAAAGGTTGTCAATATAGATACAAATTCACTGAGATCCTCCATGAGGCCTGGCTTTGAAGATATAATCCGAAGGTGTATT
CAGAGATTTTTTAGTCTAAATGATGGGCAGTCATGGTCCCAGAAACGTCACTATCAAGAAGTTACCAGTGATGGGATATTTTCCCCAACA
GCTTATCTTAATGGCCATGCAGAAACCCCAGTATATCGATTCTCGTTGGCTGATGGAACTATAGTGACTGCACAGACAAAAAGCAAACTC
TTCCGAAATCCTGTAACAAATGATCGACATGGCTTTGTCTCAACCCACTTCCTTCAGAGAGAACAGAATGGATATAGACCAAACCCAAAT
CCTGTTGGACAAGGGATTAGACCACCTATGGCTGGATGCAACAGTTCGGTAGGCGGCATGAGTATGTCGCCAAACCAAGGCTTACAGATG
CCGAGCAGCAGGGCCTATGGCTTGGCAGACCCTAGCACCACAGGGCAGATGAGTGGAGCTAGGTATGGGGGTTCCAGTAACATAGCTTCA
TTGACCCCTGGGCCAGGCATGCAATCACCATCTTCCTACCAGAACAACAACTATGGGCTCAACATGAGTAGCCCCCCACATGGGAGTCCT
GGTCTTGCCCCAAACCAGCAGAATATCATGATTTCTCCTCGTAATCGTGGGAGTCCAAAGATAGCCTCACATCAGTTTTCTCCTGTTGCA
GGTGTGCACTCTCCCATGGCATCTTCTGGCAATACTGGGAACCACAGCTTTTCCAGCAGCTCTCTCAGTGCCCTGCAAGCCATCAGTGAA
GGTGTGGGGACTTCCCTTTTATCTACTCTGTCATCACCAGGCCCCAAATTGGATAACTCTCCCAATATGAATATTACCCAACCAAGTAAA
GTAAGCAATCAGGATTCCAAGAGTCCTCTGGGCTTTTATTGCGACCAAAATCCAGTGGAGAGTTCAATGTGTCAGTCAAATAGCAGAGAT
CACCTCAGTGACAAAGAAAGTAAGGAGAGCAGTGTTGAGGGGGCAGAGAATCAAAGGGGTCCTTTGGAAAGCAAAGGTCATAAAAAATTA
CTGCAGTTACTTACCTGTTCTTCTGATGACCGGGGTCATTCCTCCTTGACCAACTCCCCCCTAGATTCAAGTTGTAAAGAATCTTCTGTT
AGTGTCACCAGCCCCTCTGGAGTCTCCTCCTCTACATCTGGAGGAGTATCCTCTACATCCAATATGCATGGGTCACTGTTACAAGAGAAG
CACCGGATTTTGCACAAGTTGCTGCAGAATGGGAATTCACCAGCTGAGGTAGCCAAGATTACTGCAGAAGCCACTGGGAAAGACACCAGC
AGTATAACTTCTTGTGGGGACGGAAATGTTGTCAAGCAGGAGCAGCTAAGTCCTAAGAAGAAGGAGAATAATGCACTTCTTAGATACCTG
CTGGACAGGGATGATCCTAGTGATGCACTCTCTAAAGAACTACAGCCCCAAGTGGAAGGAGTGGATAATAAAATGAGTCAGTGCACCAGC
TCCACCATTCCTAGCTCAAGTCAAGAGAAAGACCCTAAAATTAAGACAGAGACAAGTGAAGAGGGATCTGGAGACTTGGATAATCTAGAT
GCTATTCTTGGTGATCTGACTAGTTCTGACTTTTACAATAATTCCATATCCTCAAATGGTAGTCATCTGGGGACTAAGCAACAGGTGTTT
CAAGGAACTAATTCTCTGGGTTTGAAAAGTTCACAGTCTGTGCAGTCTATTCGTCCTCCATATAACCGAGCAGTGTCTCTGGATAGCCCT
GTTTCTGTTGGCTCAAGTCCTCCAGTAAAAAATATCAGTGCTTTCCCCATGTTACCAAAGCAACCCATGTTGGGTGGGAATCCAAGAATG
ATGGATAGTCAGGAAAATTATGGCTCAAGTATGGGAGACTGGGGCTTACCAAACTCAAAGGCCGGCAGAATGGAACCTATGAATTCAAAC
TCCATGGGAAGACCAGGAGGAGATTATAATACTTCTTTACCCAGACCTGCACTGGGTGGCTCTATTCCCACATTGCCTCTTCGGTCTAAT
AGCATACCAGGTGCGAGACCAGTATTGCAACAGCAGCAGCAGATGCTTCAAATGAGGCCTGGTGAAATCCCCATGGGAATGGGGGCTAAT
CCCTATGGCCAAGCAGCAGCATCTAACCAACTGGGTTCCTGGCCCGATGGCATGTTGTCCATGGAACAAGTTTCTCATGGCACTCAAAAT
AGGCCTCTTCTTAGGAATTCCCTGGATGATCTTGTTGGGCCACCTTCCAACCTGGAAGGCCAGAGTGACGAAAGAGCATTATTGGACCAG
CTGCACACTCTTCTCAGCAACACAGATGCCACAGGCCTGGAAGAAATTGACAGAGCTTTGGGCATTCCTGAACTTGTCAATCAGGGACAG
GCATTAGAGCCCAAACAGGATGCTTTCCAAGGCCAAGAAGCAGCAGTAATGATGGATCAGAAGGCAGGATTATATGGACAGACATACCCA
GCACAGGGGCCTCCAATGCAAGGAGGCTTTCATCTTCAGGGACAATCACCATCTTTTAACTCTATGATGAATCAGATGAACCAGCAAGGC
AATTTTCCTCTCCAAGGAATGCACCCACGAGCCAACATCATGAGACCCCGGACAAACACCCCCAAGCAACTTAGAATGCAGCTTCAGCAG
AGGCTGCAGGGCCAGCAGTTTTTGAATCAGAGCCGACAGGCACTTGAATTGAAAATGGAAAACCCTACTGCTGGTGGTGCTGCGGTGATG
AGGCCTATGATGCAGCCCCAGCAGGGTTTTCTTAATGCTCAAATGGTCGCCCAACGCAGCAGAGAGCTGCTAAGTCATCACTTCCGACAA
CAGAGGGTGGCTATGATGATGCAGCAGCAGCAGCAGCAGCAACAGCAGCAGCAGCAGCAGCAGCAGCAGCAACAGCAACAGCAACAGCAA
CAGCAGCAACAGCAGCAAACCCAGGCCTTCAGCCCACCTCCTAATGTGACTGCTTCCCCCAGCATGGATGGGCTTTTGGCAGGACCCACA
ATGCCACAAGCTCCTCCGCAACAGTTTCCATATCAACCAAATTATGGTGAATACAACACACACAATGGACCTTCCACACCAGCGAAAGAG
GGAGACACAGACAGGCCGCACCGGGCCTCCGACGGGAAGCTCCGAGGCCGGTCTAAGAGGAGCAGTGACCCGTCCCCGGCAGGGGACAAT
GAGATTGAGCGTGTGTTCGTGTGGGACTTGGATGAGACAATAATTATTTTTCACTCCTTACTCACGGGGACATTTGCATCCAGATACGGG
AAGGACACCACGACGTCCGTGCGCATTGGCCTTATGATGGAAGAGATGATCTTCAACCTTGCAGATACACATCTGTTCTTCAATGACCTG
GAGGATTGTGACCAGATCCACGTTGATGACGTCTCATCAGATGACAATGGCCAAGATTTAAGCACATACAACTTCTCCGCTGACGGCTTC
CACAGTTCGGCCCCAGGAGCCAACCTGTGCCTGGGCTCTGGCGTGCACGGCGGCGTGGACTGGATGAGGAAGCTGGCCTTCCGCTACCGG
CGGGTGAAGGAGATGTACAATACCTACAAGAACAACGTTGGTGGGAAGGAGAGCTGCTTCGAGAGGATAATGCAGAGATTCGGCAGAAAA
GCTGTCTACGTGGTGATCGGTGATGGTGTGGAAGAGGAGCAAGGAGCGAAAAAGCACAACATGCCTTTCTGGCGGATATCCTGCCACGCA
GACCTGGAGGCACTGAGGCACGCCCTGGAGCTGGAGTATTTATAGCAGGATCAGCAGCATCTCCACCTGCCATCTCACCCTCAGACCCCC
TCGCCTTCCCCACCTCCCCACCGAGAACTCCAGAGACCCAGATGTTGGACACCAGGAAGGGGCCCCACAGCCGAGACGACGTGTCCAGTG
ACCATCTCAGAAGCCGTCCATCAGTCCAAATGGGGGTTCTGAGAAGGAAAGTACCCAACATTGGCTTCGGAGTATTTGACTTTGGGGAAA
AGGGCTGGCTCGGAGTCTAGACTCTTCTGTAAGACTCACAGAACAAAAGCAAGGAATTGCTGATTTGGGGGGTGCCTGGTGATGAGGAGG
GGATGGGTTTGTCTTGTCTTCTTTTTAATTTATGGACTAGTCTCATTACTCCGGAATTATGCTCTTGTACCTGTGTGGCTGGGTTTCTTA
GTCGTTGGTTTGGTTTGGTTTTTTGAACTGGTATGTGGGGTGGTTCACAGTTCTAATGTAAGCACTCTATTCTCCAAGTTGTGCTTTGTG
GGGACAATCATTCTTTGAACATTAGAGAGGAAGGCAGTTCAAGCTGTTGAAAAGACTATTGCTTATTTTTGTTTTTAAAGACCTACTTGA
CGTCATGTGGACAGTGCACGTGCCTTACGCTACATCTTGTTTTCTAGGAAGAGGGGGATGCTGGGAAGGAATGGGTGCTTTGTGATGGAT

>57735_57735_4_NCOA3-EYA2_NCOA3_chr20_46280020_ENST00000371997_EYA2_chr20_45717877_ENST00000357410_length(amino acids)=1545AA_BP=1306
MSGLGENLDPLASDSRKRKLPCDTPGQGLTCSGEKRRREQESKYIEELAELISANLSDIDNFNVKPDKCAILKETVRQIRQIKEQGKTIS
NDDDVQKADVSSTGQGVIDKDSLGPLLLQALDGFLFVVNRDGNIVFVSENVTQYLQYKQEDLVNTSVYNILHEEDRKDFLKNLPKSTVNG
VSWTNETQRQKSHTFNCRMLMKTPHDILEDINASPEMRQRYETMQCFALSQPRAMMEEGEDLQSCMICVARRITTGERTFPSNPESFITR
HDLSGKVVNIDTNSLRSSMRPGFEDIIRRCIQRFFSLNDGQSWSQKRHYQEVTSDGIFSPTAYLNGHAETPVYRFSLADGTIVTAQTKSK
LFRNPVTNDRHGFVSTHFLQREQNGYRPNPNPVGQGIRPPMAGCNSSVGGMSMSPNQGLQMPSSRAYGLADPSTTGQMSGARYGGSSNIA
SLTPGPGMQSPSSYQNNNYGLNMSSPPHGSPGLAPNQQNIMISPRNRGSPKIASHQFSPVAGVHSPMASSGNTGNHSFSSSSLSALQAIS
EGVGTSLLSTLSSPGPKLDNSPNMNITQPSKVSNQDSKSPLGFYCDQNPVESSMCQSNSRDHLSDKESKESSVEGAENQRGPLESKGHKK
LLQLLTCSSDDRGHSSLTNSPLDSSCKESSVSVTSPSGVSSSTSGGVSSTSNMHGSLLQEKHRILHKLLQNGNSPAEVAKITAEATGKDT
SSITSCGDGNVVKQEQLSPKKKENNALLRYLLDRDDPSDALSKELQPQVEGVDNKMSQCTSSTIPSSSQEKDPKIKTETSEEGSGDLDNL
DAILGDLTSSDFYNNSISSNGSHLGTKQQVFQGTNSLGLKSSQSVQSIRPPYNRAVSLDSPVSVGSSPPVKNISAFPMLPKQPMLGGNPR
MMDSQENYGSSMGDWGLPNSKAGRMEPMNSNSMGRPGGDYNTSLPRPALGGSIPTLPLRSNSIPGARPVLQQQQQMLQMRPGEIPMGMGA
NPYGQAAASNQLGSWPDGMLSMEQVSHGTQNRPLLRNSLDDLVGPPSNLEGQSDERALLDQLHTLLSNTDATGLEEIDRALGIPELVNQG
QALEPKQDAFQGQEAAVMMDQKAGLYGQTYPAQGPPMQGGFHLQGQSPSFNSMMNQMNQQGNFPLQGMHPRANIMRPRTNTPKQLRMQLQ
QRLQGQQFLNQSRQALELKMENPTAGGAAVMRPMMQPQQGFLNAQMVAQRSRELLSHHFRQQRVAMMMQQQQQQQQQQQQQQQQQQQQQQ
QQQQQQQTQAFSPPPNVTASPSMDGLLAGPTMPQAPPQQFPYQPNYGEYNTHNGPSTPAKEGDTDRPHRASDGKLRGRSKRSSDPSPAGD
NEIERVFVWDLDETIIIFHSLLTGTFASRYGKDTTTSVRIGLMMEEMIFNLADTHLFFNDLEDCDQIHVDDVSSDDNGQDLSTYNFSADG
FHSSAPGANLCLGSGVHGGVDWMRKLAFRYRRVKEMYNTYKNNVGGKESCFERIMQRFGRKAVYVVIGDGVEEEQGAKKHNMPFWRISCH

--------------------------------------------------------------
>57735_57735_5_NCOA3-EYA2_NCOA3_chr20_46280020_ENST00000371998_EYA2_chr20_45717877_ENST00000327619_length(transcript)=5804nt_BP=4137nt
CTGCGGCTTAGTCGGTGGCGGCCGGCGGCGGCTGCGGGCTGAGCGGCGAGTTTCCGATTTAAAGCTGAGCTGCGAGGAAAATGGCGGCGG
GAGGATCAAAATACTTGCTGGATGGTGGACTCAGAGACCAATAAAAATAAACTGCTTGAACATCCTTTGACTGGTTAGCCAGTTGCTGAT
GTATATTCAAGATGAGTGGATTAGGAGAAAACTTGGATCCACTGGCCAGTGATTCACGAAAACGCAAATTGCCATGTGATACTCCAGGAC
AAGGTCTTACCTGCAGTGGTGAAAAACGGAGACGGGAGCAGGAAAGTAAATATATTGAAGAATTGGCTGAGCTGATATCTGCCAATCTTA
GTGATATTGACAATTTCAATGTCAAACCAGATAAATGTGCGATTTTAAAGGAAACAGTAAGACAGATACGTCAAATAAAAGAGCAAGGAA
AAACTATTTCCAATGATGATGATGTTCAAAAAGCCGATGTATCTTCTACAGGGCAGGGAGTTATTGATAAAGACTCCTTAGGACCGCTTT
TACTTCAGGCATTGGATGGTTTCCTATTTGTGGTGAATCGAGACGGAAACATTGTATTTGTATCAGAAAATGTCACACAATACCTGCAAT
ATAAGCAAGAGGACCTGGTTAACACAAGTGTTTACAATATCTTACATGAAGAAGACAGAAAGGATTTTCTTAAGAATTTACCAAAATCTA
CAGTTAATGGAGTTTCCTGGACAAATGAGACCCAAAGACAAAAAAGCCATACATTTAATTGCCGTATGTTGATGAAAACACCACATGATA
TTCTGGAAGACATAAACGCCAGTCCTGAAATGCGCCAGAGATATGAAACAATGCAGTGCTTTGCCCTGTCTCAGCCACGAGCTATGATGG
AGGAAGGGGAAGATTTGCAATCTTGTATGATCTGTGTGGCACGCCGCATTACTACAGGAGAAAGAACATTTCCATCAAACCCTGAGAGCT
TTATTACCAGACATGATCTTTCAGGAAAGGTTGTCAATATAGATACAAATTCACTGAGATCCTCCATGAGGCCTGGCTTTGAAGATATAA
TCCGAAGGTGTATTCAGAGATTTTTTAGTCTAAATGATGGGCAGTCATGGTCCCAGAAACGTCACTATCAAGAAGCTTATCTTAATGGCC
ATGCAGAAACCCCAGTATATCGATTCTCGTTGGCTGATGGAACTATAGTGACTGCACAGACAAAAAGCAAACTCTTCCGAAATCCTGTAA
CAAATGATCGACATGGCTTTGTCTCAACCCACTTCCTTCAGAGAGAACAGAATGGATATAGACCAAACCCAAATCCTGTTGGACAAGGGA
TTAGACCACCTATGGCTGGATGCAACAGTTCGGTAGGCGGCATGAGTATGTCGCCAAACCAAGGCTTACAGATGCCGAGCAGCAGGGCCT
ATGGCTTGGCAGACCCTAGCACCACAGGGCAGATGAGTGGAGCTAGGTATGGGGGTTCCAGTAACATAGCTTCATTGACCCCTGGGCCAG
GCATGCAATCACCATCTTCCTACCAGAACAACAACTATGGGCTCAACATGAGTAGCCCCCCACATGGGAGTCCTGGTCTTGCCCCAAACC
AGCAGAATATCATGATTTCTCCTCGTAATCGTGGGAGTCCAAAGATAGCCTCACATCAGTTTTCTCCTGTTGCAGGTGTGCACTCTCCCA
TGGCATCTTCTGGCAATACTGGGAACCACAGCTTTTCCAGCAGCTCTCTCAGTGCCCTGCAAGCCATCAGTGAAGGTGTGGGGACTTCCC
TTTTATCTACTCTGTCATCACCAGGCCCCAAATTGGATAACTCTCCCAATATGAATATTACCCAACCAAGTAAAGTAAGCAATCAGGATT
CCAAGAGTCCTCTGGGCTTTTATTGCGACCAAAATCCAGTGGAGAGTTCAATGTGTCAGTCAAATAGCAGAGATCACCTCAGTGACAAAG
AAAGTAAGGAGAGCAGTGTTGAGGGGGCAGAGAATCAAAGGGGTCCTTTGGAAAGCAAAGGTCATAAAAAATTACTGCAGTTACTTACCT
GTTCTTCTGATGACCGGGGTCATTCCTCCTTGACCAACTCCCCCCTAGATTCAAGTTGTAAAGAATCTTCTGTTAGTGTCACCAGCCCCT
CTGGAGTCTCCTCCTCTACATCTGGAGGAGTATCCTCTACATCCAATATGCATGGGTCACTGTTACAAGAGAAGCACCGGATTTTGCACA
AGTTGCTGCAGAATGGGAATTCACCAGCTGAGGTAGCCAAGATTACTGCAGAAGCCACTGGGAAAGACACCAGCAGTATAACTTCTTGTG
GGGACGGAAATGTTGTCAAGCAGGAGCAGCTAAGTCCTAAGAAGAAGGAGAATAATGCACTTCTTAGATACCTGCTGGACAGGGATGATC
CTAGTGATGCACTCTCTAAAGAACTACAGCCCCAAGTGGAAGGAGTGGATAATAAAATGAGTCAGTGCACCAGCTCCACCATTCCTAGCT
CAAGTCAAGAGAAAGACCCTAAAATTAAGACAGAGACAAGTGAAGAGGGATCTGGAGACTTGGATAATCTAGATGCTATTCTTGGTGATC
TGACTAGTTCTGACTTTTACAATAATTCCATATCCTCAAATGGTAGTCATCTGGGGACTAAGCAACAGGTGTTTCAAGGAACTAATTCTC
TGGGTTTGAAAAGTTCACAGTCTGTGCAGTCTATTCGTCCTCCATATAACCGAGCAGTGTCTCTGGATAGCCCTGTTTCTGTTGGCTCAA
GTCCTCCAGTAAAAAATATCAGTGCTTTCCCCATGTTACCAAAGCAACCCATGTTGGGTGGGAATCCAAGAATGATGGATAGTCAGGAAA
ATTATGGCTCAAGTATGGGTGGGCCAAACCGAAATGTGACTGTGACTCAGACTCCTTCCTCAGGAGACTGGGGCTTACCAAACTCAAAGG
CCGGCAGAATGGAACCTATGAATTCAAACTCCATGGGAAGACCAGGAGGAGATTATAATACTTCTTTACCCAGACCTGCACTGGGTGGCT
CTATTCCCACATTGCCTCTTCGGTCTAATAGCATACCAGGTGCGAGACCAGTATTGCAACAGCAGCAGCAGATGCTTCAAATGAGGCCTG
GTGAAATCCCCATGGGAATGGGGGCTAATCCCTATGGCCAAGCAGCAGCATCTAACCAACTGGGTTCCTGGCCCGATGGCATGTTGTCCA
TGGAACAAGTTTCTCATGGCACTCAAAATAGGCCTCTTCTTAGGAATTCCCTGGATGATCTTGTTGGGCCACCTTCCAACCTGGAAGGCC
AGAGTGACGAAAGAGCATTATTGGACCAGCTGCACACTCTTCTCAGCAACACAGATGCCACAGGCCTGGAAGAAATTGACAGAGCTTTGG
GCATTCCTGAACTTGTCAATCAGGGACAGGCATTAGAGCCCAAACAGGATGCTTTCCAAGGCCAAGAAGCAGCAGTAATGATGGATCAGA
AGGCAGGATTATATGGACAGACATACCCAGCACAGGGGCCTCCAATGCAAGGAGGCTTTCATCTTCAGGGACAATCACCATCTTTTAACT
CTATGATGAATCAGATGAACCAGCAAGGCAATTTTCCTCTCCAAGGAATGCACCCACGAGCCAACATCATGAGACCCCGGACAAACACCC
CCAAGCAACTTAGAATGCAGCTTCAGCAGAGGCTGCAGGGCCAGCAGTTTTTGAATCAGAGCCGACAGGCACTTGAATTGAAAATGGAAA
ACCCTACTGCTGGTGGTGCTGCGGTGATGAGGCCTATGATGCAGCCCCAGGTGAGCTCCCAGCAGGGTTTTCTTAATGCTCAAATGGTCG
CCCAACGCAGCAGAGAGCTGCTAAGTCATCACTTCCGACAACAGAGGGTGGCTATGATGATGCAGCAGCAGCAGCAGCAGCAACAGCAGC
AGCAGCAGCAGCAGCAGCAGCAACAGCAACAGCAACAGCAACAGCAGCAACAGCAGCAAACCCAGGCCTTCAGCCCACCTCCTAATGTGA
CTGCTTCCCCCAGCATGGATGGGCTTTTGGCAGGACCCACAATGCCACAAGCTCCTCCGCAACAGTTTCCATATCAACCAAATTATGGTG
AATACAACACACACAATGGACCTTCCACACCAGCGAAAGAGGGAGACACAGACAGGCCGCACCGGGCCTCCGACGGGAAGCTCCGAGGCC
GGTCTAAGAGGAGCAGTGACCCGTCCCCGGCAGGGGACAATGAGATTGAGCGTGTGTTCGTGTGGGACTTGGATGAGACAATAATTATTT
TTCACTCCTTACTCACGGGGACATTTGCATCCAGATACGGGAAGGACACCACGACGTCCGTGCGCATTGGCCTTATGATGGAAGAGATGA
TCTTCAACCTTGCAGATACACATCTGTTCTTCAATGACCTGGAGGATTGTGACCAGATCCACGTTGATGACGTCTCATCAGATGACAATG
GCCAAGATTTAAGCACATACAACTTCTCCGCTGACGGCTTCCACAGTTCGGCCCCAGGAGCCAACCTGTGCCTGGGCTCTGGCGTGCACG
GCGGCGTGGACTGGATGAGGAAGCTGGCCTTCCGCTACCGGCGGGTGAAGGAGATGTACAATACCTACAAGAACAACGTTGGTGGGTTGA
TAGGCACTCCCAAAAGGGAGACCTGGCTACAGCTCCGAGCTGAGCTGGAAGCTCTCACAGACCTCTGGCTGACCCACTCCCTGAAGGCAC
TAAACCTCATCAACTCCCGGCCCAACTGTGTCAATGTGCTGGTCACCACCACTCAACTAATTCCTGCCCTGGCCAAAGTCCTGCTATATG
GCCTGGGGTCTGTGTTTCCTATTGAGAACATCTACAGTGCAACCAAGACAGGGAAGGAGAGCTGCTTCGAGAGGATAATGCAGAGATTCG
GCAGAAAAGCTGTCTACGTGGTGATCGGTGATGGTGTGGAAGAGGAGCAAGGAGCGAAAAAGCACAACATGCCTTTCTGGCGGATATCCT
GCCACGCAGACCTGGAGGCACTGAGGCACGCCCTGGAGCTGGAGTATTTATAGCAGGATCAGCAGCATCTCCACCTGCCATCTCACCCTC
AGACCCCCTCGCCTTCCCCACCTCCCCACCGAGAACTCCAGAGACCCAGATGTTGGACACCAGGAAGGGGCCCCACAGCCGAGACGACGT
GTCCAGTGACCATCTCAGAAGCCGTCCATCAGTCCAAATGGGGGTTCTGAGAAGGAAAGTACCCAACATTGGCTTCGGAGTATTTGACTT
TGGGGAAAAGGGCTGGCTCGGAGTCTAGACTCTTCTGTAAGACTCACAGAACAAAAGCAAGGAATTGCTGATTTGGGGGGTGCCTGGTGA
TGAGGAGGGGATGGGTTTGTCTTGTCTTCTTTTTAATTTATGGACTAGTCTCATTACTCCGGAATTATGCTCTTGTACCTGTGTGGCTGG
GTTTCTTAGTCGTTGGTTTGGTTTGGTTTTTTGAACTGGTATGTGGGGTGGTTCACAGTTCTAATGTAAGCACTCTATTCTCCAAGTTGT
GCTTTGTGGGGACAATCATTCTTTGAACATTAGAGAGGAAGGCAGTTCAAGCTGTTGAAAAGACTATTGCTTATTTTTGTTTTTAAAGAC
CTACTTGACGTCATGTGGACAGTGCACGTGCCTTACGCTACATCTTGTTTTCTAGGAAGAGGGGGATGCTGGGAAGGAATGGGTGCTTTG

>57735_57735_5_NCOA3-EYA2_NCOA3_chr20_46280020_ENST00000371998_EYA2_chr20_45717877_ENST00000327619_length(amino acids)=1633AA_BP=1315
MSGLGENLDPLASDSRKRKLPCDTPGQGLTCSGEKRRREQESKYIEELAELISANLSDIDNFNVKPDKCAILKETVRQIRQIKEQGKTIS
NDDDVQKADVSSTGQGVIDKDSLGPLLLQALDGFLFVVNRDGNIVFVSENVTQYLQYKQEDLVNTSVYNILHEEDRKDFLKNLPKSTVNG
VSWTNETQRQKSHTFNCRMLMKTPHDILEDINASPEMRQRYETMQCFALSQPRAMMEEGEDLQSCMICVARRITTGERTFPSNPESFITR
HDLSGKVVNIDTNSLRSSMRPGFEDIIRRCIQRFFSLNDGQSWSQKRHYQEAYLNGHAETPVYRFSLADGTIVTAQTKSKLFRNPVTNDR
HGFVSTHFLQREQNGYRPNPNPVGQGIRPPMAGCNSSVGGMSMSPNQGLQMPSSRAYGLADPSTTGQMSGARYGGSSNIASLTPGPGMQS
PSSYQNNNYGLNMSSPPHGSPGLAPNQQNIMISPRNRGSPKIASHQFSPVAGVHSPMASSGNTGNHSFSSSSLSALQAISEGVGTSLLST
LSSPGPKLDNSPNMNITQPSKVSNQDSKSPLGFYCDQNPVESSMCQSNSRDHLSDKESKESSVEGAENQRGPLESKGHKKLLQLLTCSSD
DRGHSSLTNSPLDSSCKESSVSVTSPSGVSSSTSGGVSSTSNMHGSLLQEKHRILHKLLQNGNSPAEVAKITAEATGKDTSSITSCGDGN
VVKQEQLSPKKKENNALLRYLLDRDDPSDALSKELQPQVEGVDNKMSQCTSSTIPSSSQEKDPKIKTETSEEGSGDLDNLDAILGDLTSS
DFYNNSISSNGSHLGTKQQVFQGTNSLGLKSSQSVQSIRPPYNRAVSLDSPVSVGSSPPVKNISAFPMLPKQPMLGGNPRMMDSQENYGS
SMGGPNRNVTVTQTPSSGDWGLPNSKAGRMEPMNSNSMGRPGGDYNTSLPRPALGGSIPTLPLRSNSIPGARPVLQQQQQMLQMRPGEIP
MGMGANPYGQAAASNQLGSWPDGMLSMEQVSHGTQNRPLLRNSLDDLVGPPSNLEGQSDERALLDQLHTLLSNTDATGLEEIDRALGIPE
LVNQGQALEPKQDAFQGQEAAVMMDQKAGLYGQTYPAQGPPMQGGFHLQGQSPSFNSMMNQMNQQGNFPLQGMHPRANIMRPRTNTPKQL
RMQLQQRLQGQQFLNQSRQALELKMENPTAGGAAVMRPMMQPQVSSQQGFLNAQMVAQRSRELLSHHFRQQRVAMMMQQQQQQQQQQQQQ
QQQQQQQQQQQQQQQQTQAFSPPPNVTASPSMDGLLAGPTMPQAPPQQFPYQPNYGEYNTHNGPSTPAKEGDTDRPHRASDGKLRGRSKR
SSDPSPAGDNEIERVFVWDLDETIIIFHSLLTGTFASRYGKDTTTSVRIGLMMEEMIFNLADTHLFFNDLEDCDQIHVDDVSSDDNGQDL
STYNFSADGFHSSAPGANLCLGSGVHGGVDWMRKLAFRYRRVKEMYNTYKNNVGGLIGTPKRETWLQLRAELEALTDLWLTHSLKALNLI
NSRPNCVNVLVTTTQLIPALAKVLLYGLGSVFPIENIYSATKTGKESCFERIMQRFGRKAVYVVIGDGVEEEQGAKKHNMPFWRISCHAD

--------------------------------------------------------------
>57735_57735_6_NCOA3-EYA2_NCOA3_chr20_46280020_ENST00000371998_EYA2_chr20_45717877_ENST00000357410_length(transcript)=5567nt_BP=4137nt
CTGCGGCTTAGTCGGTGGCGGCCGGCGGCGGCTGCGGGCTGAGCGGCGAGTTTCCGATTTAAAGCTGAGCTGCGAGGAAAATGGCGGCGG
GAGGATCAAAATACTTGCTGGATGGTGGACTCAGAGACCAATAAAAATAAACTGCTTGAACATCCTTTGACTGGTTAGCCAGTTGCTGAT
GTATATTCAAGATGAGTGGATTAGGAGAAAACTTGGATCCACTGGCCAGTGATTCACGAAAACGCAAATTGCCATGTGATACTCCAGGAC
AAGGTCTTACCTGCAGTGGTGAAAAACGGAGACGGGAGCAGGAAAGTAAATATATTGAAGAATTGGCTGAGCTGATATCTGCCAATCTTA
GTGATATTGACAATTTCAATGTCAAACCAGATAAATGTGCGATTTTAAAGGAAACAGTAAGACAGATACGTCAAATAAAAGAGCAAGGAA
AAACTATTTCCAATGATGATGATGTTCAAAAAGCCGATGTATCTTCTACAGGGCAGGGAGTTATTGATAAAGACTCCTTAGGACCGCTTT
TACTTCAGGCATTGGATGGTTTCCTATTTGTGGTGAATCGAGACGGAAACATTGTATTTGTATCAGAAAATGTCACACAATACCTGCAAT
ATAAGCAAGAGGACCTGGTTAACACAAGTGTTTACAATATCTTACATGAAGAAGACAGAAAGGATTTTCTTAAGAATTTACCAAAATCTA
CAGTTAATGGAGTTTCCTGGACAAATGAGACCCAAAGACAAAAAAGCCATACATTTAATTGCCGTATGTTGATGAAAACACCACATGATA
TTCTGGAAGACATAAACGCCAGTCCTGAAATGCGCCAGAGATATGAAACAATGCAGTGCTTTGCCCTGTCTCAGCCACGAGCTATGATGG
AGGAAGGGGAAGATTTGCAATCTTGTATGATCTGTGTGGCACGCCGCATTACTACAGGAGAAAGAACATTTCCATCAAACCCTGAGAGCT
TTATTACCAGACATGATCTTTCAGGAAAGGTTGTCAATATAGATACAAATTCACTGAGATCCTCCATGAGGCCTGGCTTTGAAGATATAA
TCCGAAGGTGTATTCAGAGATTTTTTAGTCTAAATGATGGGCAGTCATGGTCCCAGAAACGTCACTATCAAGAAGCTTATCTTAATGGCC
ATGCAGAAACCCCAGTATATCGATTCTCGTTGGCTGATGGAACTATAGTGACTGCACAGACAAAAAGCAAACTCTTCCGAAATCCTGTAA
CAAATGATCGACATGGCTTTGTCTCAACCCACTTCCTTCAGAGAGAACAGAATGGATATAGACCAAACCCAAATCCTGTTGGACAAGGGA
TTAGACCACCTATGGCTGGATGCAACAGTTCGGTAGGCGGCATGAGTATGTCGCCAAACCAAGGCTTACAGATGCCGAGCAGCAGGGCCT
ATGGCTTGGCAGACCCTAGCACCACAGGGCAGATGAGTGGAGCTAGGTATGGGGGTTCCAGTAACATAGCTTCATTGACCCCTGGGCCAG
GCATGCAATCACCATCTTCCTACCAGAACAACAACTATGGGCTCAACATGAGTAGCCCCCCACATGGGAGTCCTGGTCTTGCCCCAAACC
AGCAGAATATCATGATTTCTCCTCGTAATCGTGGGAGTCCAAAGATAGCCTCACATCAGTTTTCTCCTGTTGCAGGTGTGCACTCTCCCA
TGGCATCTTCTGGCAATACTGGGAACCACAGCTTTTCCAGCAGCTCTCTCAGTGCCCTGCAAGCCATCAGTGAAGGTGTGGGGACTTCCC
TTTTATCTACTCTGTCATCACCAGGCCCCAAATTGGATAACTCTCCCAATATGAATATTACCCAACCAAGTAAAGTAAGCAATCAGGATT
CCAAGAGTCCTCTGGGCTTTTATTGCGACCAAAATCCAGTGGAGAGTTCAATGTGTCAGTCAAATAGCAGAGATCACCTCAGTGACAAAG
AAAGTAAGGAGAGCAGTGTTGAGGGGGCAGAGAATCAAAGGGGTCCTTTGGAAAGCAAAGGTCATAAAAAATTACTGCAGTTACTTACCT
GTTCTTCTGATGACCGGGGTCATTCCTCCTTGACCAACTCCCCCCTAGATTCAAGTTGTAAAGAATCTTCTGTTAGTGTCACCAGCCCCT
CTGGAGTCTCCTCCTCTACATCTGGAGGAGTATCCTCTACATCCAATATGCATGGGTCACTGTTACAAGAGAAGCACCGGATTTTGCACA
AGTTGCTGCAGAATGGGAATTCACCAGCTGAGGTAGCCAAGATTACTGCAGAAGCCACTGGGAAAGACACCAGCAGTATAACTTCTTGTG
GGGACGGAAATGTTGTCAAGCAGGAGCAGCTAAGTCCTAAGAAGAAGGAGAATAATGCACTTCTTAGATACCTGCTGGACAGGGATGATC
CTAGTGATGCACTCTCTAAAGAACTACAGCCCCAAGTGGAAGGAGTGGATAATAAAATGAGTCAGTGCACCAGCTCCACCATTCCTAGCT
CAAGTCAAGAGAAAGACCCTAAAATTAAGACAGAGACAAGTGAAGAGGGATCTGGAGACTTGGATAATCTAGATGCTATTCTTGGTGATC
TGACTAGTTCTGACTTTTACAATAATTCCATATCCTCAAATGGTAGTCATCTGGGGACTAAGCAACAGGTGTTTCAAGGAACTAATTCTC
TGGGTTTGAAAAGTTCACAGTCTGTGCAGTCTATTCGTCCTCCATATAACCGAGCAGTGTCTCTGGATAGCCCTGTTTCTGTTGGCTCAA
GTCCTCCAGTAAAAAATATCAGTGCTTTCCCCATGTTACCAAAGCAACCCATGTTGGGTGGGAATCCAAGAATGATGGATAGTCAGGAAA
ATTATGGCTCAAGTATGGGTGGGCCAAACCGAAATGTGACTGTGACTCAGACTCCTTCCTCAGGAGACTGGGGCTTACCAAACTCAAAGG
CCGGCAGAATGGAACCTATGAATTCAAACTCCATGGGAAGACCAGGAGGAGATTATAATACTTCTTTACCCAGACCTGCACTGGGTGGCT
CTATTCCCACATTGCCTCTTCGGTCTAATAGCATACCAGGTGCGAGACCAGTATTGCAACAGCAGCAGCAGATGCTTCAAATGAGGCCTG
GTGAAATCCCCATGGGAATGGGGGCTAATCCCTATGGCCAAGCAGCAGCATCTAACCAACTGGGTTCCTGGCCCGATGGCATGTTGTCCA
TGGAACAAGTTTCTCATGGCACTCAAAATAGGCCTCTTCTTAGGAATTCCCTGGATGATCTTGTTGGGCCACCTTCCAACCTGGAAGGCC
AGAGTGACGAAAGAGCATTATTGGACCAGCTGCACACTCTTCTCAGCAACACAGATGCCACAGGCCTGGAAGAAATTGACAGAGCTTTGG
GCATTCCTGAACTTGTCAATCAGGGACAGGCATTAGAGCCCAAACAGGATGCTTTCCAAGGCCAAGAAGCAGCAGTAATGATGGATCAGA
AGGCAGGATTATATGGACAGACATACCCAGCACAGGGGCCTCCAATGCAAGGAGGCTTTCATCTTCAGGGACAATCACCATCTTTTAACT
CTATGATGAATCAGATGAACCAGCAAGGCAATTTTCCTCTCCAAGGAATGCACCCACGAGCCAACATCATGAGACCCCGGACAAACACCC
CCAAGCAACTTAGAATGCAGCTTCAGCAGAGGCTGCAGGGCCAGCAGTTTTTGAATCAGAGCCGACAGGCACTTGAATTGAAAATGGAAA
ACCCTACTGCTGGTGGTGCTGCGGTGATGAGGCCTATGATGCAGCCCCAGGTGAGCTCCCAGCAGGGTTTTCTTAATGCTCAAATGGTCG
CCCAACGCAGCAGAGAGCTGCTAAGTCATCACTTCCGACAACAGAGGGTGGCTATGATGATGCAGCAGCAGCAGCAGCAGCAACAGCAGC
AGCAGCAGCAGCAGCAGCAGCAACAGCAACAGCAACAGCAACAGCAGCAACAGCAGCAAACCCAGGCCTTCAGCCCACCTCCTAATGTGA
CTGCTTCCCCCAGCATGGATGGGCTTTTGGCAGGACCCACAATGCCACAAGCTCCTCCGCAACAGTTTCCATATCAACCAAATTATGGTG
AATACAACACACACAATGGACCTTCCACACCAGCGAAAGAGGGAGACACAGACAGGCCGCACCGGGCCTCCGACGGGAAGCTCCGAGGCC
GGTCTAAGAGGAGCAGTGACCCGTCCCCGGCAGGGGACAATGAGATTGAGCGTGTGTTCGTGTGGGACTTGGATGAGACAATAATTATTT
TTCACTCCTTACTCACGGGGACATTTGCATCCAGATACGGGAAGGACACCACGACGTCCGTGCGCATTGGCCTTATGATGGAAGAGATGA
TCTTCAACCTTGCAGATACACATCTGTTCTTCAATGACCTGGAGGATTGTGACCAGATCCACGTTGATGACGTCTCATCAGATGACAATG
GCCAAGATTTAAGCACATACAACTTCTCCGCTGACGGCTTCCACAGTTCGGCCCCAGGAGCCAACCTGTGCCTGGGCTCTGGCGTGCACG
GCGGCGTGGACTGGATGAGGAAGCTGGCCTTCCGCTACCGGCGGGTGAAGGAGATGTACAATACCTACAAGAACAACGTTGGTGGGAAGG
AGAGCTGCTTCGAGAGGATAATGCAGAGATTCGGCAGAAAAGCTGTCTACGTGGTGATCGGTGATGGTGTGGAAGAGGAGCAAGGAGCGA
AAAAGCACAACATGCCTTTCTGGCGGATATCCTGCCACGCAGACCTGGAGGCACTGAGGCACGCCCTGGAGCTGGAGTATTTATAGCAGG
ATCAGCAGCATCTCCACCTGCCATCTCACCCTCAGACCCCCTCGCCTTCCCCACCTCCCCACCGAGAACTCCAGAGACCCAGATGTTGGA
CACCAGGAAGGGGCCCCACAGCCGAGACGACGTGTCCAGTGACCATCTCAGAAGCCGTCCATCAGTCCAAATGGGGGTTCTGAGAAGGAA
AGTACCCAACATTGGCTTCGGAGTATTTGACTTTGGGGAAAAGGGCTGGCTCGGAGTCTAGACTCTTCTGTAAGACTCACAGAACAAAAG
CAAGGAATTGCTGATTTGGGGGGTGCCTGGTGATGAGGAGGGGATGGGTTTGTCTTGTCTTCTTTTTAATTTATGGACTAGTCTCATTAC
TCCGGAATTATGCTCTTGTACCTGTGTGGCTGGGTTTCTTAGTCGTTGGTTTGGTTTGGTTTTTTGAACTGGTATGTGGGGTGGTTCACA
GTTCTAATGTAAGCACTCTATTCTCCAAGTTGTGCTTTGTGGGGACAATCATTCTTTGAACATTAGAGAGGAAGGCAGTTCAAGCTGTTG
AAAAGACTATTGCTTATTTTTGTTTTTAAAGACCTACTTGACGTCATGTGGACAGTGCACGTGCCTTACGCTACATCTTGTTTTCTAGGA

>57735_57735_6_NCOA3-EYA2_NCOA3_chr20_46280020_ENST00000371998_EYA2_chr20_45717877_ENST00000357410_length(amino acids)=1554AA_BP=1315
MSGLGENLDPLASDSRKRKLPCDTPGQGLTCSGEKRRREQESKYIEELAELISANLSDIDNFNVKPDKCAILKETVRQIRQIKEQGKTIS
NDDDVQKADVSSTGQGVIDKDSLGPLLLQALDGFLFVVNRDGNIVFVSENVTQYLQYKQEDLVNTSVYNILHEEDRKDFLKNLPKSTVNG
VSWTNETQRQKSHTFNCRMLMKTPHDILEDINASPEMRQRYETMQCFALSQPRAMMEEGEDLQSCMICVARRITTGERTFPSNPESFITR
HDLSGKVVNIDTNSLRSSMRPGFEDIIRRCIQRFFSLNDGQSWSQKRHYQEAYLNGHAETPVYRFSLADGTIVTAQTKSKLFRNPVTNDR
HGFVSTHFLQREQNGYRPNPNPVGQGIRPPMAGCNSSVGGMSMSPNQGLQMPSSRAYGLADPSTTGQMSGARYGGSSNIASLTPGPGMQS
PSSYQNNNYGLNMSSPPHGSPGLAPNQQNIMISPRNRGSPKIASHQFSPVAGVHSPMASSGNTGNHSFSSSSLSALQAISEGVGTSLLST
LSSPGPKLDNSPNMNITQPSKVSNQDSKSPLGFYCDQNPVESSMCQSNSRDHLSDKESKESSVEGAENQRGPLESKGHKKLLQLLTCSSD
DRGHSSLTNSPLDSSCKESSVSVTSPSGVSSSTSGGVSSTSNMHGSLLQEKHRILHKLLQNGNSPAEVAKITAEATGKDTSSITSCGDGN
VVKQEQLSPKKKENNALLRYLLDRDDPSDALSKELQPQVEGVDNKMSQCTSSTIPSSSQEKDPKIKTETSEEGSGDLDNLDAILGDLTSS
DFYNNSISSNGSHLGTKQQVFQGTNSLGLKSSQSVQSIRPPYNRAVSLDSPVSVGSSPPVKNISAFPMLPKQPMLGGNPRMMDSQENYGS
SMGGPNRNVTVTQTPSSGDWGLPNSKAGRMEPMNSNSMGRPGGDYNTSLPRPALGGSIPTLPLRSNSIPGARPVLQQQQQMLQMRPGEIP
MGMGANPYGQAAASNQLGSWPDGMLSMEQVSHGTQNRPLLRNSLDDLVGPPSNLEGQSDERALLDQLHTLLSNTDATGLEEIDRALGIPE
LVNQGQALEPKQDAFQGQEAAVMMDQKAGLYGQTYPAQGPPMQGGFHLQGQSPSFNSMMNQMNQQGNFPLQGMHPRANIMRPRTNTPKQL
RMQLQQRLQGQQFLNQSRQALELKMENPTAGGAAVMRPMMQPQVSSQQGFLNAQMVAQRSRELLSHHFRQQRVAMMMQQQQQQQQQQQQQ
QQQQQQQQQQQQQQQQTQAFSPPPNVTASPSMDGLLAGPTMPQAPPQQFPYQPNYGEYNTHNGPSTPAKEGDTDRPHRASDGKLRGRSKR
SSDPSPAGDNEIERVFVWDLDETIIIFHSLLTGTFASRYGKDTTTSVRIGLMMEEMIFNLADTHLFFNDLEDCDQIHVDDVSSDDNGQDL
STYNFSADGFHSSAPGANLCLGSGVHGGVDWMRKLAFRYRRVKEMYNTYKNNVGGKESCFERIMQRFGRKAVYVVIGDGVEEEQGAKKHN

--------------------------------------------------------------
>57735_57735_7_NCOA3-EYA2_NCOA3_chr20_46280020_ENST00000372004_EYA2_chr20_45717877_ENST00000327619_length(transcript)=5817nt_BP=4150nt
AGCCGCTCCACAGCGACGGCAGCGGCTGCGGCTTAGTCGGTGGCGGCCGGCGGCGGCTGCGGGCTGAGCGGCGAGTTTCCGATTTAAAGC
TGAGCTGCGAGGAAAATGGCGGCGGGAGGATCAAAATACTTGCTGGATGGTGGACTCAGAGACCAATAAAAATAAACTGCTTGAACATCC
TTTGACTGGTTAGCCAGTTGCTGATGTATATTCAAGATGAGTGGATTAGGAGAAAACTTGGATCCACTGGCCAGTGATTCACGAAAACGC
AAATTGCCATGTGATACTCCAGGACAAGGTCTTACCTGCAGTGGTGAAAAACGGAGACGGGAGCAGGAAAGTAAATATATTGAAGAATTG
GCTGAGCTGATATCTGCCAATCTTAGTGATATTGACAATTTCAATGTCAAACCAGATAAATGTGCGATTTTAAAGGAAACAGTAAGACAG
ATACGTCAAATAAAAGAGCAAGGAAAAACTATTTCCAATGATGATGATGTTCAAAAAGCCGATGTATCTTCTACAGGGCAGGGAGTTATT
GATAAAGACTCCTTAGGACCGCTTTTACTTCAGGCATTGGATGGTTTCCTATTTGTGGTGAATCGAGACGGAAACATTGTATTTGTATCA
GAAAATGTCACACAATACCTGCAATATAAGCAAGAGGACCTGGTTAACACAAGTGTTTACAATATCTTACATGAAGAAGACAGAAAGGAT
TTTCTTAAGAATTTACCAAAATCTACAGTTAATGGAGTTTCCTGGACAAATGAGACCCAAAGACAAAAAAGCCATACATTTAATTGCCGT
ATGTTGATGAAAACACCACATGATATTCTGGAAGACATAAACGCCAGTCCTGAAATGCGCCAGAGATATGAAACAATGCAGTGCTTTGCC
CTGTCTCAGCCACGAGCTATGATGGAGGAAGGGGAAGATTTGCAATCTTGTATGATCTGTGTGGCACGCCGCATTACTACAGGAGAAAGA
ACATTTCCATCAAACCCTGAGAGCTTTATTACCAGACATGATCTTTCAGGAAAGGTTGTCAATATAGATACAAATTCACTGAGATCCTCC
ATGAGGCCTGGCTTTGAAGATATAATCCGAAGGTGTATTCAGAGATTTTTTAGTCTAAATGATGGGCAGTCATGGTCCCAGAAACGTCAC
TATCAAGAAGCTTATCTTAATGGCCATGCAGAAACCCCAGTATATCGATTCTCGTTGGCTGATGGAACTATAGTGACTGCACAGACAAAA
AGCAAACTCTTCCGAAATCCTGTAACAAATGATCGACATGGCTTTGTCTCAACCCACTTCCTTCAGAGAGAACAGAATGGATATAGACCA
AACCCAAATCCTGTTGGACAAGGGATTAGACCACCTATGGCTGGATGCAACAGTTCGGTAGGCGGCATGAGTATGTCGCCAAACCAAGGC
TTACAGATGCCGAGCAGCAGGGCCTATGGCTTGGCAGACCCTAGCACCACAGGGCAGATGAGTGGAGCTAGGTATGGGGGTTCCAGTAAC
ATAGCTTCATTGACCCCTGGGCCAGGCATGCAATCACCATCTTCCTACCAGAACAACAACTATGGGCTCAACATGAGTAGCCCCCCACAT
GGGAGTCCTGGTCTTGCCCCAAACCAGCAGAATATCATGATTTCTCCTCGTAATCGTGGGAGTCCAAAGATAGCCTCACATCAGTTTTCT
CCTGTTGCAGGTGTGCACTCTCCCATGGCATCTTCTGGCAATACTGGGAACCACAGCTTTTCCAGCAGCTCTCTCAGTGCCCTGCAAGCC
ATCAGTGAAGGTGTGGGGACTTCCCTTTTATCTACTCTGTCATCACCAGGCCCCAAATTGGATAACTCTCCCAATATGAATATTACCCAA
CCAAGTAAAGTAAGCAATCAGGATTCCAAGAGTCCTCTGGGCTTTTATTGCGACCAAAATCCAGTGGAGAGTTCAATGTGTCAGTCAAAT
AGCAGAGATCACCTCAGTGACAAAGAAAGTAAGGAGAGCAGTGTTGAGGGGGCAGAGAATCAAAGGGGTCCTTTGGAAAGCAAAGGTCAT
AAAAAATTACTGCAGTTACTTACCTGTTCTTCTGATGACCGGGGTCATTCCTCCTTGACCAACTCCCCCCTAGATTCAAGTTGTAAAGAA
TCTTCTGTTAGTGTCACCAGCCCCTCTGGAGTCTCCTCCTCTACATCTGGAGGAGTATCCTCTACATCCAATATGCATGGGTCACTGTTA
CAAGAGAAGCACCGGATTTTGCACAAGTTGCTGCAGAATGGGAATTCACCAGCTGAGGTAGCCAAGATTACTGCAGAAGCCACTGGGAAA
GACACCAGCAGTATAACTTCTTGTGGGGACGGAAATGTTGTCAAGCAGGAGCAGCTAAGTCCTAAGAAGAAGGAGAATAATGCACTTCTT
AGATACCTGCTGGACAGGGATGATCCTAGTGATGCACTCTCTAAAGAACTACAGCCCCAAGTGGAAGGAGTGGATAATAAAATGAGTCAG
TGCACCAGCTCCACCATTCCTAGCTCAAGTCAAGAGAAAGACCCTAAAATTAAGACAGAGACAAGTGAAGAGGGATCTGGAGACTTGGAT
AATCTAGATGCTATTCTTGGTGATCTGACTAGTTCTGACTTTTACAATAATTCCATATCCTCAAATGGTAGTCATCTGGGGACTAAGCAA
CAGGTGTTTCAAGGAACTAATTCTCTGGGTTTGAAAAGTTCACAGTCTGTGCAGTCTATTCGTCCTCCATATAACCGAGCAGTGTCTCTG
GATAGCCCTGTTTCTGTTGGCTCAAGTCCTCCAGTAAAAAATATCAGTGCTTTCCCCATGTTACCAAAGCAACCCATGTTGGGTGGGAAT
CCAAGAATGATGGATAGTCAGGAAAATTATGGCTCAAGTATGGGTGGGCCAAACCGAAATGTGACTGTGACTCAGACTCCTTCCTCAGGA
GACTGGGGCTTACCAAACTCAAAGGCCGGCAGAATGGAACCTATGAATTCAAACTCCATGGGAAGACCAGGAGGAGATTATAATACTTCT
TTACCCAGACCTGCACTGGGTGGCTCTATTCCCACATTGCCTCTTCGGTCTAATAGCATACCAGGTGCGAGACCAGTATTGCAACAGCAG
CAGCAGATGCTTCAAATGAGGCCTGGTGAAATCCCCATGGGAATGGGGGCTAATCCCTATGGCCAAGCAGCAGCATCTAACCAACTGGGT
TCCTGGCCCGATGGCATGTTGTCCATGGAACAAGTTTCTCATGGCACTCAAAATAGGCCTCTTCTTAGGAATTCCCTGGATGATCTTGTT
GGGCCACCTTCCAACCTGGAAGGCCAGAGTGACGAAAGAGCATTATTGGACCAGCTGCACACTCTTCTCAGCAACACAGATGCCACAGGC
CTGGAAGAAATTGACAGAGCTTTGGGCATTCCTGAACTTGTCAATCAGGGACAGGCATTAGAGCCCAAACAGGATGCTTTCCAAGGCCAA
GAAGCAGCAGTAATGATGGATCAGAAGGCAGGATTATATGGACAGACATACCCAGCACAGGGGCCTCCAATGCAAGGAGGCTTTCATCTT
CAGGGACAATCACCATCTTTTAACTCTATGATGAATCAGATGAACCAGCAAGGCAATTTTCCTCTCCAAGGAATGCACCCACGAGCCAAC
ATCATGAGACCCCGGACAAACACCCCCAAGCAACTTAGAATGCAGCTTCAGCAGAGGCTGCAGGGCCAGCAGTTTTTGAATCAGAGCCGA
CAGGCACTTGAATTGAAAATGGAAAACCCTACTGCTGGTGGTGCTGCGGTGATGAGGCCTATGATGCAGCCCCAGCAGGGTTTTCTTAAT
GCTCAAATGGTCGCCCAACGCAGCAGAGAGCTGCTAAGTCATCACTTCCGACAACAGAGGGTGGCTATGATGATGCAGCAGCAGCAGCAG
CAGCAACAGCAGCAGCAGCAGCAGCAGCAGCAGCAACAGCAACAGCAACAGCAACAGCAGCAACAGCAGCAAACCCAGGCCTTCAGCCCA
CCTCCTAATGTGACTGCTTCCCCCAGCATGGATGGGCTTTTGGCAGGACCCACAATGCCACAAGCTCCTCCGCAACAGTTTCCATATCAA
CCAAATTATGGTGAATACAACACACACAATGGACCTTCCACACCAGCGAAAGAGGGAGACACAGACAGGCCGCACCGGGCCTCCGACGGG
AAGCTCCGAGGCCGGTCTAAGAGGAGCAGTGACCCGTCCCCGGCAGGGGACAATGAGATTGAGCGTGTGTTCGTGTGGGACTTGGATGAG
ACAATAATTATTTTTCACTCCTTACTCACGGGGACATTTGCATCCAGATACGGGAAGGACACCACGACGTCCGTGCGCATTGGCCTTATG
ATGGAAGAGATGATCTTCAACCTTGCAGATACACATCTGTTCTTCAATGACCTGGAGGATTGTGACCAGATCCACGTTGATGACGTCTCA
TCAGATGACAATGGCCAAGATTTAAGCACATACAACTTCTCCGCTGACGGCTTCCACAGTTCGGCCCCAGGAGCCAACCTGTGCCTGGGC
TCTGGCGTGCACGGCGGCGTGGACTGGATGAGGAAGCTGGCCTTCCGCTACCGGCGGGTGAAGGAGATGTACAATACCTACAAGAACAAC
GTTGGTGGGTTGATAGGCACTCCCAAAAGGGAGACCTGGCTACAGCTCCGAGCTGAGCTGGAAGCTCTCACAGACCTCTGGCTGACCCAC
TCCCTGAAGGCACTAAACCTCATCAACTCCCGGCCCAACTGTGTCAATGTGCTGGTCACCACCACTCAACTAATTCCTGCCCTGGCCAAA
GTCCTGCTATATGGCCTGGGGTCTGTGTTTCCTATTGAGAACATCTACAGTGCAACCAAGACAGGGAAGGAGAGCTGCTTCGAGAGGATA
ATGCAGAGATTCGGCAGAAAAGCTGTCTACGTGGTGATCGGTGATGGTGTGGAAGAGGAGCAAGGAGCGAAAAAGCACAACATGCCTTTC
TGGCGGATATCCTGCCACGCAGACCTGGAGGCACTGAGGCACGCCCTGGAGCTGGAGTATTTATAGCAGGATCAGCAGCATCTCCACCTG
CCATCTCACCCTCAGACCCCCTCGCCTTCCCCACCTCCCCACCGAGAACTCCAGAGACCCAGATGTTGGACACCAGGAAGGGGCCCCACA
GCCGAGACGACGTGTCCAGTGACCATCTCAGAAGCCGTCCATCAGTCCAAATGGGGGTTCTGAGAAGGAAAGTACCCAACATTGGCTTCG
GAGTATTTGACTTTGGGGAAAAGGGCTGGCTCGGAGTCTAGACTCTTCTGTAAGACTCACAGAACAAAAGCAAGGAATTGCTGATTTGGG
GGGTGCCTGGTGATGAGGAGGGGATGGGTTTGTCTTGTCTTCTTTTTAATTTATGGACTAGTCTCATTACTCCGGAATTATGCTCTTGTA
CCTGTGTGGCTGGGTTTCTTAGTCGTTGGTTTGGTTTGGTTTTTTGAACTGGTATGTGGGGTGGTTCACAGTTCTAATGTAAGCACTCTA
TTCTCCAAGTTGTGCTTTGTGGGGACAATCATTCTTTGAACATTAGAGAGGAAGGCAGTTCAAGCTGTTGAAAAGACTATTGCTTATTTT
TGTTTTTAAAGACCTACTTGACGTCATGTGGACAGTGCACGTGCCTTACGCTACATCTTGTTTTCTAGGAAGAGGGGGATGCTGGGAAGG

>57735_57735_7_NCOA3-EYA2_NCOA3_chr20_46280020_ENST00000372004_EYA2_chr20_45717877_ENST00000327619_length(amino acids)=1629AA_BP=1311
MSGLGENLDPLASDSRKRKLPCDTPGQGLTCSGEKRRREQESKYIEELAELISANLSDIDNFNVKPDKCAILKETVRQIRQIKEQGKTIS
NDDDVQKADVSSTGQGVIDKDSLGPLLLQALDGFLFVVNRDGNIVFVSENVTQYLQYKQEDLVNTSVYNILHEEDRKDFLKNLPKSTVNG
VSWTNETQRQKSHTFNCRMLMKTPHDILEDINASPEMRQRYETMQCFALSQPRAMMEEGEDLQSCMICVARRITTGERTFPSNPESFITR
HDLSGKVVNIDTNSLRSSMRPGFEDIIRRCIQRFFSLNDGQSWSQKRHYQEAYLNGHAETPVYRFSLADGTIVTAQTKSKLFRNPVTNDR
HGFVSTHFLQREQNGYRPNPNPVGQGIRPPMAGCNSSVGGMSMSPNQGLQMPSSRAYGLADPSTTGQMSGARYGGSSNIASLTPGPGMQS
PSSYQNNNYGLNMSSPPHGSPGLAPNQQNIMISPRNRGSPKIASHQFSPVAGVHSPMASSGNTGNHSFSSSSLSALQAISEGVGTSLLST
LSSPGPKLDNSPNMNITQPSKVSNQDSKSPLGFYCDQNPVESSMCQSNSRDHLSDKESKESSVEGAENQRGPLESKGHKKLLQLLTCSSD
DRGHSSLTNSPLDSSCKESSVSVTSPSGVSSSTSGGVSSTSNMHGSLLQEKHRILHKLLQNGNSPAEVAKITAEATGKDTSSITSCGDGN
VVKQEQLSPKKKENNALLRYLLDRDDPSDALSKELQPQVEGVDNKMSQCTSSTIPSSSQEKDPKIKTETSEEGSGDLDNLDAILGDLTSS
DFYNNSISSNGSHLGTKQQVFQGTNSLGLKSSQSVQSIRPPYNRAVSLDSPVSVGSSPPVKNISAFPMLPKQPMLGGNPRMMDSQENYGS
SMGGPNRNVTVTQTPSSGDWGLPNSKAGRMEPMNSNSMGRPGGDYNTSLPRPALGGSIPTLPLRSNSIPGARPVLQQQQQMLQMRPGEIP
MGMGANPYGQAAASNQLGSWPDGMLSMEQVSHGTQNRPLLRNSLDDLVGPPSNLEGQSDERALLDQLHTLLSNTDATGLEEIDRALGIPE
LVNQGQALEPKQDAFQGQEAAVMMDQKAGLYGQTYPAQGPPMQGGFHLQGQSPSFNSMMNQMNQQGNFPLQGMHPRANIMRPRTNTPKQL
RMQLQQRLQGQQFLNQSRQALELKMENPTAGGAAVMRPMMQPQQGFLNAQMVAQRSRELLSHHFRQQRVAMMMQQQQQQQQQQQQQQQQQ
QQQQQQQQQQQQTQAFSPPPNVTASPSMDGLLAGPTMPQAPPQQFPYQPNYGEYNTHNGPSTPAKEGDTDRPHRASDGKLRGRSKRSSDP
SPAGDNEIERVFVWDLDETIIIFHSLLTGTFASRYGKDTTTSVRIGLMMEEMIFNLADTHLFFNDLEDCDQIHVDDVSSDDNGQDLSTYN
FSADGFHSSAPGANLCLGSGVHGGVDWMRKLAFRYRRVKEMYNTYKNNVGGLIGTPKRETWLQLRAELEALTDLWLTHSLKALNLINSRP
NCVNVLVTTTQLIPALAKVLLYGLGSVFPIENIYSATKTGKESCFERIMQRFGRKAVYVVIGDGVEEEQGAKKHNMPFWRISCHADLEAL

--------------------------------------------------------------
>57735_57735_8_NCOA3-EYA2_NCOA3_chr20_46280020_ENST00000372004_EYA2_chr20_45717877_ENST00000357410_length(transcript)=5580nt_BP=4150nt
AGCCGCTCCACAGCGACGGCAGCGGCTGCGGCTTAGTCGGTGGCGGCCGGCGGCGGCTGCGGGCTGAGCGGCGAGTTTCCGATTTAAAGC
TGAGCTGCGAGGAAAATGGCGGCGGGAGGATCAAAATACTTGCTGGATGGTGGACTCAGAGACCAATAAAAATAAACTGCTTGAACATCC
TTTGACTGGTTAGCCAGTTGCTGATGTATATTCAAGATGAGTGGATTAGGAGAAAACTTGGATCCACTGGCCAGTGATTCACGAAAACGC
AAATTGCCATGTGATACTCCAGGACAAGGTCTTACCTGCAGTGGTGAAAAACGGAGACGGGAGCAGGAAAGTAAATATATTGAAGAATTG
GCTGAGCTGATATCTGCCAATCTTAGTGATATTGACAATTTCAATGTCAAACCAGATAAATGTGCGATTTTAAAGGAAACAGTAAGACAG
ATACGTCAAATAAAAGAGCAAGGAAAAACTATTTCCAATGATGATGATGTTCAAAAAGCCGATGTATCTTCTACAGGGCAGGGAGTTATT
GATAAAGACTCCTTAGGACCGCTTTTACTTCAGGCATTGGATGGTTTCCTATTTGTGGTGAATCGAGACGGAAACATTGTATTTGTATCA
GAAAATGTCACACAATACCTGCAATATAAGCAAGAGGACCTGGTTAACACAAGTGTTTACAATATCTTACATGAAGAAGACAGAAAGGAT
TTTCTTAAGAATTTACCAAAATCTACAGTTAATGGAGTTTCCTGGACAAATGAGACCCAAAGACAAAAAAGCCATACATTTAATTGCCGT
ATGTTGATGAAAACACCACATGATATTCTGGAAGACATAAACGCCAGTCCTGAAATGCGCCAGAGATATGAAACAATGCAGTGCTTTGCC
CTGTCTCAGCCACGAGCTATGATGGAGGAAGGGGAAGATTTGCAATCTTGTATGATCTGTGTGGCACGCCGCATTACTACAGGAGAAAGA
ACATTTCCATCAAACCCTGAGAGCTTTATTACCAGACATGATCTTTCAGGAAAGGTTGTCAATATAGATACAAATTCACTGAGATCCTCC
ATGAGGCCTGGCTTTGAAGATATAATCCGAAGGTGTATTCAGAGATTTTTTAGTCTAAATGATGGGCAGTCATGGTCCCAGAAACGTCAC
TATCAAGAAGCTTATCTTAATGGCCATGCAGAAACCCCAGTATATCGATTCTCGTTGGCTGATGGAACTATAGTGACTGCACAGACAAAA
AGCAAACTCTTCCGAAATCCTGTAACAAATGATCGACATGGCTTTGTCTCAACCCACTTCCTTCAGAGAGAACAGAATGGATATAGACCA
AACCCAAATCCTGTTGGACAAGGGATTAGACCACCTATGGCTGGATGCAACAGTTCGGTAGGCGGCATGAGTATGTCGCCAAACCAAGGC
TTACAGATGCCGAGCAGCAGGGCCTATGGCTTGGCAGACCCTAGCACCACAGGGCAGATGAGTGGAGCTAGGTATGGGGGTTCCAGTAAC
ATAGCTTCATTGACCCCTGGGCCAGGCATGCAATCACCATCTTCCTACCAGAACAACAACTATGGGCTCAACATGAGTAGCCCCCCACAT
GGGAGTCCTGGTCTTGCCCCAAACCAGCAGAATATCATGATTTCTCCTCGTAATCGTGGGAGTCCAAAGATAGCCTCACATCAGTTTTCT
CCTGTTGCAGGTGTGCACTCTCCCATGGCATCTTCTGGCAATACTGGGAACCACAGCTTTTCCAGCAGCTCTCTCAGTGCCCTGCAAGCC
ATCAGTGAAGGTGTGGGGACTTCCCTTTTATCTACTCTGTCATCACCAGGCCCCAAATTGGATAACTCTCCCAATATGAATATTACCCAA
CCAAGTAAAGTAAGCAATCAGGATTCCAAGAGTCCTCTGGGCTTTTATTGCGACCAAAATCCAGTGGAGAGTTCAATGTGTCAGTCAAAT
AGCAGAGATCACCTCAGTGACAAAGAAAGTAAGGAGAGCAGTGTTGAGGGGGCAGAGAATCAAAGGGGTCCTTTGGAAAGCAAAGGTCAT
AAAAAATTACTGCAGTTACTTACCTGTTCTTCTGATGACCGGGGTCATTCCTCCTTGACCAACTCCCCCCTAGATTCAAGTTGTAAAGAA
TCTTCTGTTAGTGTCACCAGCCCCTCTGGAGTCTCCTCCTCTACATCTGGAGGAGTATCCTCTACATCCAATATGCATGGGTCACTGTTA
CAAGAGAAGCACCGGATTTTGCACAAGTTGCTGCAGAATGGGAATTCACCAGCTGAGGTAGCCAAGATTACTGCAGAAGCCACTGGGAAA
GACACCAGCAGTATAACTTCTTGTGGGGACGGAAATGTTGTCAAGCAGGAGCAGCTAAGTCCTAAGAAGAAGGAGAATAATGCACTTCTT
AGATACCTGCTGGACAGGGATGATCCTAGTGATGCACTCTCTAAAGAACTACAGCCCCAAGTGGAAGGAGTGGATAATAAAATGAGTCAG
TGCACCAGCTCCACCATTCCTAGCTCAAGTCAAGAGAAAGACCCTAAAATTAAGACAGAGACAAGTGAAGAGGGATCTGGAGACTTGGAT
AATCTAGATGCTATTCTTGGTGATCTGACTAGTTCTGACTTTTACAATAATTCCATATCCTCAAATGGTAGTCATCTGGGGACTAAGCAA
CAGGTGTTTCAAGGAACTAATTCTCTGGGTTTGAAAAGTTCACAGTCTGTGCAGTCTATTCGTCCTCCATATAACCGAGCAGTGTCTCTG
GATAGCCCTGTTTCTGTTGGCTCAAGTCCTCCAGTAAAAAATATCAGTGCTTTCCCCATGTTACCAAAGCAACCCATGTTGGGTGGGAAT
CCAAGAATGATGGATAGTCAGGAAAATTATGGCTCAAGTATGGGTGGGCCAAACCGAAATGTGACTGTGACTCAGACTCCTTCCTCAGGA
GACTGGGGCTTACCAAACTCAAAGGCCGGCAGAATGGAACCTATGAATTCAAACTCCATGGGAAGACCAGGAGGAGATTATAATACTTCT
TTACCCAGACCTGCACTGGGTGGCTCTATTCCCACATTGCCTCTTCGGTCTAATAGCATACCAGGTGCGAGACCAGTATTGCAACAGCAG
CAGCAGATGCTTCAAATGAGGCCTGGTGAAATCCCCATGGGAATGGGGGCTAATCCCTATGGCCAAGCAGCAGCATCTAACCAACTGGGT
TCCTGGCCCGATGGCATGTTGTCCATGGAACAAGTTTCTCATGGCACTCAAAATAGGCCTCTTCTTAGGAATTCCCTGGATGATCTTGTT
GGGCCACCTTCCAACCTGGAAGGCCAGAGTGACGAAAGAGCATTATTGGACCAGCTGCACACTCTTCTCAGCAACACAGATGCCACAGGC
CTGGAAGAAATTGACAGAGCTTTGGGCATTCCTGAACTTGTCAATCAGGGACAGGCATTAGAGCCCAAACAGGATGCTTTCCAAGGCCAA
GAAGCAGCAGTAATGATGGATCAGAAGGCAGGATTATATGGACAGACATACCCAGCACAGGGGCCTCCAATGCAAGGAGGCTTTCATCTT
CAGGGACAATCACCATCTTTTAACTCTATGATGAATCAGATGAACCAGCAAGGCAATTTTCCTCTCCAAGGAATGCACCCACGAGCCAAC
ATCATGAGACCCCGGACAAACACCCCCAAGCAACTTAGAATGCAGCTTCAGCAGAGGCTGCAGGGCCAGCAGTTTTTGAATCAGAGCCGA
CAGGCACTTGAATTGAAAATGGAAAACCCTACTGCTGGTGGTGCTGCGGTGATGAGGCCTATGATGCAGCCCCAGCAGGGTTTTCTTAAT
GCTCAAATGGTCGCCCAACGCAGCAGAGAGCTGCTAAGTCATCACTTCCGACAACAGAGGGTGGCTATGATGATGCAGCAGCAGCAGCAG
CAGCAACAGCAGCAGCAGCAGCAGCAGCAGCAGCAACAGCAACAGCAACAGCAACAGCAGCAACAGCAGCAAACCCAGGCCTTCAGCCCA
CCTCCTAATGTGACTGCTTCCCCCAGCATGGATGGGCTTTTGGCAGGACCCACAATGCCACAAGCTCCTCCGCAACAGTTTCCATATCAA
CCAAATTATGGTGAATACAACACACACAATGGACCTTCCACACCAGCGAAAGAGGGAGACACAGACAGGCCGCACCGGGCCTCCGACGGG
AAGCTCCGAGGCCGGTCTAAGAGGAGCAGTGACCCGTCCCCGGCAGGGGACAATGAGATTGAGCGTGTGTTCGTGTGGGACTTGGATGAG
ACAATAATTATTTTTCACTCCTTACTCACGGGGACATTTGCATCCAGATACGGGAAGGACACCACGACGTCCGTGCGCATTGGCCTTATG
ATGGAAGAGATGATCTTCAACCTTGCAGATACACATCTGTTCTTCAATGACCTGGAGGATTGTGACCAGATCCACGTTGATGACGTCTCA
TCAGATGACAATGGCCAAGATTTAAGCACATACAACTTCTCCGCTGACGGCTTCCACAGTTCGGCCCCAGGAGCCAACCTGTGCCTGGGC
TCTGGCGTGCACGGCGGCGTGGACTGGATGAGGAAGCTGGCCTTCCGCTACCGGCGGGTGAAGGAGATGTACAATACCTACAAGAACAAC
GTTGGTGGGAAGGAGAGCTGCTTCGAGAGGATAATGCAGAGATTCGGCAGAAAAGCTGTCTACGTGGTGATCGGTGATGGTGTGGAAGAG
GAGCAAGGAGCGAAAAAGCACAACATGCCTTTCTGGCGGATATCCTGCCACGCAGACCTGGAGGCACTGAGGCACGCCCTGGAGCTGGAG
TATTTATAGCAGGATCAGCAGCATCTCCACCTGCCATCTCACCCTCAGACCCCCTCGCCTTCCCCACCTCCCCACCGAGAACTCCAGAGA
CCCAGATGTTGGACACCAGGAAGGGGCCCCACAGCCGAGACGACGTGTCCAGTGACCATCTCAGAAGCCGTCCATCAGTCCAAATGGGGG
TTCTGAGAAGGAAAGTACCCAACATTGGCTTCGGAGTATTTGACTTTGGGGAAAAGGGCTGGCTCGGAGTCTAGACTCTTCTGTAAGACT
CACAGAACAAAAGCAAGGAATTGCTGATTTGGGGGGTGCCTGGTGATGAGGAGGGGATGGGTTTGTCTTGTCTTCTTTTTAATTTATGGA
CTAGTCTCATTACTCCGGAATTATGCTCTTGTACCTGTGTGGCTGGGTTTCTTAGTCGTTGGTTTGGTTTGGTTTTTTGAACTGGTATGT
GGGGTGGTTCACAGTTCTAATGTAAGCACTCTATTCTCCAAGTTGTGCTTTGTGGGGACAATCATTCTTTGAACATTAGAGAGGAAGGCA
GTTCAAGCTGTTGAAAAGACTATTGCTTATTTTTGTTTTTAAAGACCTACTTGACGTCATGTGGACAGTGCACGTGCCTTACGCTACATC
TTGTTTTCTAGGAAGAGGGGGATGCTGGGAAGGAATGGGTGCTTTGTGATGGATAAAAGGCATTAAATAAAACCACGTTTACATTTTGAA

>57735_57735_8_NCOA3-EYA2_NCOA3_chr20_46280020_ENST00000372004_EYA2_chr20_45717877_ENST00000357410_length(amino acids)=1550AA_BP=1311
MSGLGENLDPLASDSRKRKLPCDTPGQGLTCSGEKRRREQESKYIEELAELISANLSDIDNFNVKPDKCAILKETVRQIRQIKEQGKTIS
NDDDVQKADVSSTGQGVIDKDSLGPLLLQALDGFLFVVNRDGNIVFVSENVTQYLQYKQEDLVNTSVYNILHEEDRKDFLKNLPKSTVNG
VSWTNETQRQKSHTFNCRMLMKTPHDILEDINASPEMRQRYETMQCFALSQPRAMMEEGEDLQSCMICVARRITTGERTFPSNPESFITR
HDLSGKVVNIDTNSLRSSMRPGFEDIIRRCIQRFFSLNDGQSWSQKRHYQEAYLNGHAETPVYRFSLADGTIVTAQTKSKLFRNPVTNDR
HGFVSTHFLQREQNGYRPNPNPVGQGIRPPMAGCNSSVGGMSMSPNQGLQMPSSRAYGLADPSTTGQMSGARYGGSSNIASLTPGPGMQS
PSSYQNNNYGLNMSSPPHGSPGLAPNQQNIMISPRNRGSPKIASHQFSPVAGVHSPMASSGNTGNHSFSSSSLSALQAISEGVGTSLLST
LSSPGPKLDNSPNMNITQPSKVSNQDSKSPLGFYCDQNPVESSMCQSNSRDHLSDKESKESSVEGAENQRGPLESKGHKKLLQLLTCSSD
DRGHSSLTNSPLDSSCKESSVSVTSPSGVSSSTSGGVSSTSNMHGSLLQEKHRILHKLLQNGNSPAEVAKITAEATGKDTSSITSCGDGN
VVKQEQLSPKKKENNALLRYLLDRDDPSDALSKELQPQVEGVDNKMSQCTSSTIPSSSQEKDPKIKTETSEEGSGDLDNLDAILGDLTSS
DFYNNSISSNGSHLGTKQQVFQGTNSLGLKSSQSVQSIRPPYNRAVSLDSPVSVGSSPPVKNISAFPMLPKQPMLGGNPRMMDSQENYGS
SMGGPNRNVTVTQTPSSGDWGLPNSKAGRMEPMNSNSMGRPGGDYNTSLPRPALGGSIPTLPLRSNSIPGARPVLQQQQQMLQMRPGEIP
MGMGANPYGQAAASNQLGSWPDGMLSMEQVSHGTQNRPLLRNSLDDLVGPPSNLEGQSDERALLDQLHTLLSNTDATGLEEIDRALGIPE
LVNQGQALEPKQDAFQGQEAAVMMDQKAGLYGQTYPAQGPPMQGGFHLQGQSPSFNSMMNQMNQQGNFPLQGMHPRANIMRPRTNTPKQL
RMQLQQRLQGQQFLNQSRQALELKMENPTAGGAAVMRPMMQPQQGFLNAQMVAQRSRELLSHHFRQQRVAMMMQQQQQQQQQQQQQQQQQ
QQQQQQQQQQQQTQAFSPPPNVTASPSMDGLLAGPTMPQAPPQQFPYQPNYGEYNTHNGPSTPAKEGDTDRPHRASDGKLRGRSKRSSDP
SPAGDNEIERVFVWDLDETIIIFHSLLTGTFASRYGKDTTTSVRIGLMMEEMIFNLADTHLFFNDLEDCDQIHVDDVSSDDNGQDLSTYN
FSADGFHSSAPGANLCLGSGVHGGVDWMRKLAFRYRRVKEMYNTYKNNVGGKESCFERIMQRFGRKAVYVVIGDGVEEEQGAKKHNMPFW

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Fusion Gene PPI Analysis for NCOA3-EYA2


check button Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in

ChiPPI page.


check button Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160)
HgeneHgene's interactorsTgeneTgene's interactors


check button - Retained PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenStill interaction with
HgeneNCOA3chr20:46280020chr20:45717877ENST00000371997+20231023_10931306.33333333333331416.0CREBBP
HgeneNCOA3chr20:46280020chr20:45717877ENST00000371998+20231023_10931315.33333333333331425.0CREBBP
HgeneNCOA3chr20:46280020chr20:45717877ENST00000372004+20231023_10931311.33333333333331421.0CREBBP


check button - Lost PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


check button - Retained PPIs, but lost function due to frame-shift fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


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Related Drugs for NCOA3-EYA2


check button Drugs targeting genes involved in this fusion gene.
(DrugBank Version 5.1.8 2021-05-08)
PartnerGeneUniProtAccDrugBank IDDrug nameDrug activityDrug typeDrug status

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Related Diseases for NCOA3-EYA2


check button Diseases associated with fusion partners.
(DisGeNet 4.0)
PartnerGeneDisease IDDisease name# pubmedsSource