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Center for Computational Systems Medicine
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Fusion Gene Summary

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Fusion Gene ORF analysis

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Fusion Genomic Features

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Fusion Protein Features

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Fusion Gene Sequence

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Fusion Gene PPI analysis

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Related Drugs

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Related Diseases

Fusion gene:NCOR1-MPRIP (FusionGDB2 ID:57839)

Fusion Gene Summary for NCOR1-MPRIP

check button Fusion gene summary
Fusion gene informationFusion gene name: NCOR1-MPRIP
Fusion gene ID: 57839
HgeneTgene
Gene symbol

NCOR1

MPRIP

Gene ID

9611

23164

Gene namenuclear receptor corepressor 1myosin phosphatase Rho interacting protein
SynonymsN-CoR|N-CoR1|PPP1R109|TRAC1|hN-CoRM-RIP|MRIP|RHOIP3|RIP3|p116Rip
Cytomap

17p12-p11.2

17p11.2

Type of geneprotein-codingprotein-coding
Descriptionnuclear receptor corepressor 1protein phosphatase 1, regulatory subunit 109thyroid hormone- and retinoic acid receptor-associated corepressor 1myosin phosphatase Rho-interacting proteinRho interacting protein 3
Modification date2020031320200313
UniProtAcc

O75376

Q6WCQ1

Ensembl transtripts involved in fusion geneENST00000268712, ENST00000395851, 
ENST00000395848, ENST00000395857, 
ENST00000583226, 		ENST00000395807, 
ENST00000395806, ENST00000341712, 
ENST00000395804, ENST00000395811, 
ENST00000444976, 
Fusion gene scores* DoF score30 X 30 X 13=117009 X 7 X 6=378
# samples 339
** MAII scorelog2(33/11700*10)=-5.14789869511231
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0		log2(9/378*10)=-2.0703893278914
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0
Context

PubMed: NCOR1 [Title/Abstract] AND MPRIP [Title/Abstract] AND fusion [Title/Abstract]

Most frequent breakpointNCOR1(16075117)-MPRIP(16979024), # samples:1
Anticipated loss of major functional domain due to fusion event.NCOR1-MPRIP seems lost the major protein functional domain in Hgene partner, which is a cell metabolism gene due to the frame-shifted ORF.
NCOR1-MPRIP seems lost the major protein functional domain in Hgene partner, which is a CGC due to the frame-shifted ORF.
NCOR1-MPRIP seems lost the major protein functional domain in Hgene partner, which is a epigenetic factor due to the frame-shifted ORF.
NCOR1-MPRIP seems lost the major protein functional domain in Tgene partner, which is a essential gene due to the frame-shifted ORF.
* DoF score (Degree of Frequency) = # partners X # break points X # cancer types
** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)

check button Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez
PartnerGeneGO IDGO termPubMed ID
HgeneNCOR1

GO:0046329

negative regulation of JNK cascade

11931768


check buttonFusion gene breakpoints across NCOR1 (5'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check buttonFusion gene breakpoints across MPRIP (3'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check button Fusion gene information from two resources (ChiTars 5.0 and ChimerDB 4.0)
* All genome coordinats were lifted-over on hg19.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
SourceDiseaseSampleHgeneHchrHbpHstrandTgeneTchrTbpTstrand
ChimerDB4UCSTCGA-N8-A4PQ-01ANCOR1chr17

16075117

-MPRIPchr17

16979024

+


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Fusion Gene ORF analysis for NCOR1-MPRIP

check button Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
ORFHenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrand
5CDS-3UTRENST00000268712ENST00000395807NCOR1chr17

16075117

-MPRIPchr17

16979024

+
5CDS-3UTRENST00000395851ENST00000395807NCOR1chr17

16075117

-MPRIPchr17

16979024

+
5CDS-intronENST00000268712ENST00000395806NCOR1chr17

16075117

-MPRIPchr17

16979024

+
5CDS-intronENST00000395851ENST00000395806NCOR1chr17

16075117

-MPRIPchr17

16979024

+
Frame-shiftENST00000268712ENST00000341712NCOR1chr17

16075117

-MPRIPchr17

16979024

+
Frame-shiftENST00000268712ENST00000395804NCOR1chr17

16075117

-MPRIPchr17

16979024

+
Frame-shiftENST00000268712ENST00000395811NCOR1chr17

16075117

-MPRIPchr17

16979024

+
Frame-shiftENST00000268712ENST00000444976NCOR1chr17

16075117

-MPRIPchr17

16979024

+
In-frameENST00000395851ENST00000341712NCOR1chr17

16075117

-MPRIPchr17

16979024

+
In-frameENST00000395851ENST00000395804NCOR1chr17

16075117

-MPRIPchr17

16979024

+
In-frameENST00000395851ENST00000395811NCOR1chr17

16075117

-MPRIPchr17

16979024

+
In-frameENST00000395851ENST00000444976NCOR1chr17

16075117

-MPRIPchr17

16979024

+
intron-3CDSENST00000395848ENST00000341712NCOR1chr17

16075117

-MPRIPchr17

16979024

+
intron-3CDSENST00000395848ENST00000395804NCOR1chr17

16075117

-MPRIPchr17

16979024

+
intron-3CDSENST00000395848ENST00000395811NCOR1chr17

16075117

-MPRIPchr17

16979024

+
intron-3CDSENST00000395848ENST00000444976NCOR1chr17

16075117

-MPRIPchr17

16979024

+
intron-3CDSENST00000395857ENST00000341712NCOR1chr17

16075117

-MPRIPchr17

16979024

+
intron-3CDSENST00000395857ENST00000395804NCOR1chr17

16075117

-MPRIPchr17

16979024

+
intron-3CDSENST00000395857ENST00000395811NCOR1chr17

16075117

-MPRIPchr17

16979024

+
intron-3CDSENST00000395857ENST00000444976NCOR1chr17

16075117

-MPRIPchr17

16979024

+
intron-3CDSENST00000583226ENST00000341712NCOR1chr17

16075117

-MPRIPchr17

16979024

+
intron-3CDSENST00000583226ENST00000395804NCOR1chr17

16075117

-MPRIPchr17

16979024

+
intron-3CDSENST00000583226ENST00000395811NCOR1chr17

16075117

-MPRIPchr17

16979024

+
intron-3CDSENST00000583226ENST00000444976NCOR1chr17

16075117

-MPRIPchr17

16979024

+
intron-3UTRENST00000395848ENST00000395807NCOR1chr17

16075117

-MPRIPchr17

16979024

+
intron-3UTRENST00000395857ENST00000395807NCOR1chr17

16075117

-MPRIPchr17

16979024

+
intron-3UTRENST00000583226ENST00000395807NCOR1chr17

16075117

-MPRIPchr17

16979024

+
intron-intronENST00000395848ENST00000395806NCOR1chr17

16075117

-MPRIPchr17

16979024

+
intron-intronENST00000395857ENST00000395806NCOR1chr17

16075117

-MPRIPchr17

16979024

+
intron-intronENST00000583226ENST00000395806NCOR1chr17

16075117

-MPRIPchr17

16979024

+

check buttonORFfinder result based on the fusion transcript sequence of in-frame fusion genes.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandSeq length
(transcript)		BP loci
(transcript)		Predicted start
(transcript)		Predicted stop
(transcript)		Seq length
(amino acids)
ENST00000395851NCOR1chr1716075117-ENST00000395811MPRIPchr1716979024+112274792034721150
ENST00000395851NCOR1chr1716075117-ENST00000444976MPRIPchr1716979024+35204792033581112
ENST00000395851NCOR1chr1716075117-ENST00000395804MPRIPchr1716979024+34344792034331138
ENST00000395851NCOR1chr1716075117-ENST00000341712MPRIPchr1716979024+42024792034331137

check buttonDeepORF prediction of the coding potential based on the fusion transcript sequence of in-frame fusion genes. DeepORF is a coding potential classifier based on convolutional neural network by comparing the real Ribo-seq data. If the no-coding score < 0.5 and coding score > 0.5, then the in-frame fusion transcript is predicted as being likely translated.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandNo-coding scoreCoding score
ENST00000395851ENST00000395811NCOR1chr1716075117-MPRIPchr1716979024+0.0005893590.9994106
ENST00000395851ENST00000444976NCOR1chr1716075117-MPRIPchr1716979024+0.0148733090.9851267
ENST00000395851ENST00000395804NCOR1chr1716075117-MPRIPchr1716979024+0.0125161810.98748386
ENST00000395851ENST00000341712NCOR1chr1716075117-MPRIPchr1716979024+0.0061745280.99382544

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Fusion Genomic Features for NCOR1-MPRIP


check buttonFusionAI prediction of the potential fusion gene breakpoint based on the pre-mature RNA sequence context (+/- 5kb of individual partner genes, total 20kb length sequence). FusionAI is a fusion gene breakpoint classifier based on convolutional neural network by comparing the fusion positive and negative sequence context of ~ 20K fusion gene data. From here, we can have the relative potentency of the 20K genomic sequence how individual sequnce will be likely used as the gene fusion breakpoints.
HgeneHchrHbpHstrandTgeneTchrTbpTstrand1-pp (fusion gene breakpoint)
NCOR1chr1716075116-MPRIPchr1716979023+1.88E-070.99999976
NCOR1chr1716075116-MPRIPchr1716979023+1.88E-070.99999976

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions. We integrated a total of 44 different types of human genomic feature loci information across five big categories including virus integration sites, repeats, structural variants, chromatin states, and gene expression regulation. More details are in help page.
genomic feature

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions that are ovelapped with the top 1% feature importance score regions. More details are in help page.
genomic feature of top 1%

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Fusion Protein Features for NCOR1-MPRIP


check button Four levels of functional features of fusion genes
Go to FGviewer search page for the most frequent breakpoint (https://ccsmweb.uth.edu/FGviewer/chr17:16075117/chr17:16979024)
- FGviewer provides the online visualization of the retention search of the protein functional features across DNA, RNA, protein, and pathological levels.
- How to search
1. Put your fusion gene symbol.
2. Press the tab key until there will be shown the breakpoint information filled.
4. Go down and press 'Search' tab twice.
4. Go down to have the hyperlink of the search result.
5. Click the hyperlink.
6. See the FGviewer result for your fusion gene.
FGviewer

check buttonMain function of each fusion partner protein. (from UniProt)
HgeneTgene
NCOR1

O75376

MPRIP

Q6WCQ1

FUNCTION: Mediates transcriptional repression by certain nuclear receptors (PubMed:20812024). Part of a complex which promotes histone deacetylation and the formation of repressive chromatin structures which may impede the access of basal transcription factors. Participates in the transcriptional repressor activity produced by BCL6. Recruited by ZBTB7A to the androgen response elements/ARE on target genes, negatively regulates androgen receptor signaling and androgen-induced cell proliferation (PubMed:20812024). Mediates the NR1D1-dependent repression and circadian regulation of TSHB expression (By similarity). The NCOR1-HDAC3 complex regulates the circadian expression of the core clock gene ARTNL/BMAL1 and the genes involved in lipid metabolism in the liver (By similarity). {ECO:0000250|UniProtKB:Q60974, ECO:0000269|PubMed:14527417, ECO:0000269|PubMed:20812024}.FUNCTION: Targets myosin phosphatase to the actin cytoskeleton. Required for the regulation of the actin cytoskeleton by RhoA and ROCK1. Depletion leads to an increased number of stress fibers in smooth muscle cells through stabilization of actin fibers by phosphorylated myosin. Overexpression of MRIP as well as its F-actin-binding region leads to disassembly of stress fibers in neuronal cells. {ECO:0000250|UniProtKB:P97434, ECO:0000269|PubMed:15545284, ECO:0000269|PubMed:16257966}.

check buttonRetention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at

download page


* Minus value of BPloci means that the break pointn is located before the CDS.
- In-frame and retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneNCOR1chr17:16075117chr17:16979024ENST00000268712-44658_641452441.0Compositional biasNote=Poly-Gln
HgeneNCOR1chr17:16075117chr17:16979024ENST00000395851-34558_641452338.0Compositional biasNote=Poly-Gln
TgeneMPRIPchr17:16075117chr17:16979024ENST00000341712024673_977411231.0Coiled coilOntology_term=ECO:0000255
TgeneMPRIPchr17:16075117chr17:16979024ENST00000395804023673_977411026.0Coiled coilOntology_term=ECO:0000255
TgeneMPRIPchr17:16075117chr17:16979024ENST00000395811023673_977411039.0Coiled coilOntology_term=ECO:0000255
TgeneMPRIPchr17:16075117chr17:16979024ENST00000444976022673_977411001.0Coiled coilOntology_term=ECO:0000255
TgeneMPRIPchr17:16075117chr17:16979024ENST00000341712024179_252411231.0Compositional biasNote=Ser-rich
TgeneMPRIPchr17:16075117chr17:16979024ENST00000395804023179_252411026.0Compositional biasNote=Ser-rich
TgeneMPRIPchr17:16075117chr17:16979024ENST00000395811023179_252411039.0Compositional biasNote=Ser-rich
TgeneMPRIPchr17:16075117chr17:16979024ENST00000444976022179_252411001.0Compositional biasNote=Ser-rich
TgeneMPRIPchr17:16075117chr17:16979024ENST00000341712024387_483411231.0DomainPH 2
TgeneMPRIPchr17:16075117chr17:16979024ENST0000034171202443_150411231.0DomainPH 1
TgeneMPRIPchr17:16075117chr17:16979024ENST00000395804023387_483411026.0DomainPH 2
TgeneMPRIPchr17:16075117chr17:16979024ENST0000039580402343_150411026.0DomainPH 1
TgeneMPRIPchr17:16075117chr17:16979024ENST00000395811023387_483411039.0DomainPH 2
TgeneMPRIPchr17:16075117chr17:16979024ENST0000039581102343_150411039.0DomainPH 1
TgeneMPRIPchr17:16075117chr17:16979024ENST00000444976022387_483411001.0DomainPH 2
TgeneMPRIPchr17:16075117chr17:16979024ENST0000044497602243_150411001.0DomainPH 1

- In-frame and not-retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneNCOR1chr17:16075117chr17:16979024ENST00000268712-446174_2161452441.0Coiled coilOntology_term=ECO:0000255
HgeneNCOR1chr17:16075117chr17:16979024ENST00000268712-446299_3281452441.0Coiled coilOntology_term=ECO:0000255
HgeneNCOR1chr17:16075117chr17:16979024ENST00000268712-446501_5571452441.0Coiled coilOntology_term=ECO:0000255
HgeneNCOR1chr17:16075117chr17:16979024ENST00000395848-119174_2160915.0Coiled coilOntology_term=ECO:0000255
HgeneNCOR1chr17:16075117chr17:16979024ENST00000395848-119299_3280915.0Coiled coilOntology_term=ECO:0000255
HgeneNCOR1chr17:16075117chr17:16979024ENST00000395848-119501_5570915.0Coiled coilOntology_term=ECO:0000255
HgeneNCOR1chr17:16075117chr17:16979024ENST00000395851-345174_2161452338.0Coiled coilOntology_term=ECO:0000255
HgeneNCOR1chr17:16075117chr17:16979024ENST00000395851-345299_3281452338.0Coiled coilOntology_term=ECO:0000255
HgeneNCOR1chr17:16075117chr17:16979024ENST00000395851-345501_5571452338.0Coiled coilOntology_term=ECO:0000255
HgeneNCOR1chr17:16075117chr17:16979024ENST00000268712-4461032_10351452441.0Compositional biasNote=Poly-Pro
HgeneNCOR1chr17:16075117chr17:16979024ENST00000268712-4461707_17121452441.0Compositional biasNote=Poly-Ala
HgeneNCOR1chr17:16075117chr17:16979024ENST00000268712-4461952_19631452441.0Compositional biasNote=Poly-Ser
HgeneNCOR1chr17:16075117chr17:16979024ENST00000268712-446593_6031452441.0Compositional biasNote=Poly-Ala
HgeneNCOR1chr17:16075117chr17:16979024ENST00000268712-446607_6171452441.0Compositional biasNote=Pro-rich
HgeneNCOR1chr17:16075117chr17:16979024ENST00000395848-1191032_10350915.0Compositional biasNote=Poly-Pro
HgeneNCOR1chr17:16075117chr17:16979024ENST00000395848-1191707_17120915.0Compositional biasNote=Poly-Ala
HgeneNCOR1chr17:16075117chr17:16979024ENST00000395848-1191952_19630915.0Compositional biasNote=Poly-Ser
HgeneNCOR1chr17:16075117chr17:16979024ENST00000395848-11958_640915.0Compositional biasNote=Poly-Gln
HgeneNCOR1chr17:16075117chr17:16979024ENST00000395848-119593_6030915.0Compositional biasNote=Poly-Ala
HgeneNCOR1chr17:16075117chr17:16979024ENST00000395848-119607_6170915.0Compositional biasNote=Pro-rich
HgeneNCOR1chr17:16075117chr17:16979024ENST00000395851-3451032_10351452338.0Compositional biasNote=Poly-Pro
HgeneNCOR1chr17:16075117chr17:16979024ENST00000395851-3451707_17121452338.0Compositional biasNote=Poly-Ala
HgeneNCOR1chr17:16075117chr17:16979024ENST00000395851-3451952_19631452338.0Compositional biasNote=Poly-Ser
HgeneNCOR1chr17:16075117chr17:16979024ENST00000395851-345593_6031452338.0Compositional biasNote=Poly-Ala
HgeneNCOR1chr17:16075117chr17:16979024ENST00000395851-345607_6171452338.0Compositional biasNote=Pro-rich
HgeneNCOR1chr17:16075117chr17:16979024ENST00000268712-446435_4861452441.0DomainSANT 1
HgeneNCOR1chr17:16075117chr17:16979024ENST00000268712-446623_6741452441.0DomainSANT 2
HgeneNCOR1chr17:16075117chr17:16979024ENST00000395848-119435_4860915.0DomainSANT 1
HgeneNCOR1chr17:16075117chr17:16979024ENST00000395848-119623_6740915.0DomainSANT 2
HgeneNCOR1chr17:16075117chr17:16979024ENST00000395851-345435_4861452338.0DomainSANT 1
HgeneNCOR1chr17:16075117chr17:16979024ENST00000395851-345623_6741452338.0DomainSANT 2
HgeneNCOR1chr17:16075117chr17:16979024ENST00000268712-4461933_19371452441.0MotifNote=CORNR box 1
HgeneNCOR1chr17:16075117chr17:16979024ENST00000268712-4462055_20591452441.0MotifNote=CORNR box 2
HgeneNCOR1chr17:16075117chr17:16979024ENST00000268712-4462263_22671452441.0MotifNote=CORNR box 3
HgeneNCOR1chr17:16075117chr17:16979024ENST00000395848-1191933_19370915.0MotifNote=CORNR box 1
HgeneNCOR1chr17:16075117chr17:16979024ENST00000395848-1192055_20590915.0MotifNote=CORNR box 2
HgeneNCOR1chr17:16075117chr17:16979024ENST00000395848-1192263_22670915.0MotifNote=CORNR box 3
HgeneNCOR1chr17:16075117chr17:16979024ENST00000395851-3451933_19371452338.0MotifNote=CORNR box 1
HgeneNCOR1chr17:16075117chr17:16979024ENST00000395851-3452055_20591452338.0MotifNote=CORNR box 2
HgeneNCOR1chr17:16075117chr17:16979024ENST00000395851-3452263_22671452338.0MotifNote=CORNR box 3
HgeneNCOR1chr17:16075117chr17:16979024ENST00000268712-4462032_21151452441.0RegionID1
HgeneNCOR1chr17:16075117chr17:16979024ENST00000268712-4462212_22731452441.0RegionID2
HgeneNCOR1chr17:16075117chr17:16979024ENST00000395848-1192032_21150915.0RegionID1
HgeneNCOR1chr17:16075117chr17:16979024ENST00000395848-1192212_22730915.0RegionID2
HgeneNCOR1chr17:16075117chr17:16979024ENST00000395851-3452032_21151452338.0RegionID1
HgeneNCOR1chr17:16075117chr17:16979024ENST00000395851-3452212_22731452338.0RegionID2


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Fusion Gene Sequence for NCOR1-MPRIP


check button For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. To have fusion amino acid sequence, we ran ORFfinder and chose the longest ORF among the all predicted ones.
>57839_57839_1_NCOR1-MPRIP_NCOR1_chr17_16075117_ENST00000395851_MPRIP_chr17_16979024_ENST00000341712_length(transcript)=4202nt_BP=479nt
ATTGGCATTGATCTCACAGTCTGGTGAGGACTTCTTTACTGATAATGTCAAGTTCAGGTTATCCTCCCAACCAAGGAGCATTCAGCACAG
AACAAAGTCGTTATCCTCCTCACTCTGTCCAGTATACATTTCCCAACACCCGCCACCAGCAGGAGTTCGCAGTCCCTGATTATCGTTCCT
CTCATCTTGAAGTGAGTCAGGCATCACAGCTTTTGCAGCAACAGCAGCAGCAACAGCTTCGAAGGCGACCTTCCTTGCTTTCAGAATTTC
ACCCAGGTTCTGACAGGCCTCAAGAAAGGAGAACTAGTTATGAACCGTTTCATCCAGGCCCATCCCCAGTGGATCATGATTCACTGGAAT
CGAAGCGACCACGTCTGGAACAGGTTTCTGATTCTCATTTTCAGCGTGTCAGTGCTGCGGTTTTGCCTTTAGTGCACCCGCTGCCAGAAG
GGCTGAGGGCTTCTGCAGATGCTAAGAAGGCAAAACCCATTTATGGCGGTTGGCTGCTCCTGGCTCCAGATGGGACCGACTTTGACAACC
CAGTGCACCGGTCTCGGAAATGGCAGCGACGGTTCTTCATCCTTTACGAGCACGGCCTCTTGCGCTACGCCCTGGATGAGATGCCCACGA
CCCTTCCTCAGGGCACCATCAACATGAACCAGTGCACAGATGTGGTGGATGGGGAGGGCCGCACGGGCCAGAAGTTCTCCCTGTGTATTC
TGACGCCTGAGAAGGAGCATTTCATCCGGGCGGAGACCAAGGAGATCGTCAGTGGGTGGCTGGAGATGCTCATGGTCTATCCCCGGACCA
ACAAGCAGAATCAGAAGAAGAAACGGAAAGTGGAGCCCCCCACACCACAGGAGCCTGGGCCTGCCAAGGTGGCTGTTACCAGCAGCAGCA
GCAGCAGCAGCAGCAGCAGCAGCATCCCCAGTGCTGAGAAAGTCCCCACCACCAAGTCCACACTCTGGCAGGAAGAAATGAGGACCAAGG
ACCAGCCAGATGGCAGCAGCCTGAGTCCAGCTCAGAGTCCCAGCCAGAGCCAGCCTCCTGCTGCCAGCTCCCTGCGGGAACCTGGGCTAG
AGAGCAAAGAAGAGGAGAGCGCCATGAGTAGCGACCGCATGGACTGTGGCCGCAAAGTCCGGGTGGAGAGCGGCTACTTCTCTCTGGAGA
AGACCAAACAGGACTTGAAGGCTGAAGAACAGCAGCTGCCCCCGCCGCTCTCCCCTCCCAGCCCCAGCACCCCCAACCACAGGAGGTCCC
AGGTGATTGAAAAGTTTGAGGCCTTGGACATTGAGAAGGCAGAGCACATGGAGACCAATGCAGTGGGGCCCTCACCATCCAGCGACACAC
GCCAGGGCCGCAGCGAGAAGAGGGCGTTCCCTAGGAAGCGGGACTTCACCAATGAAGCCCCCCCAGCTCCTCTCCCAGACGCCTCGGCTT
CCCCCCTGTCTCCACACCGAAGAGCCAAGTCACTGGACAGGAGGTCCACGGAGCCCTCCGTGACGCCCGACCTGCTGAATTTCAAGAAAG
GCTGGCTGACTAAGCAGTATGAGGACGGCCAGTGGAAGAAACACTGGTTTGTCCTCGCCGATCAAAGCCTGAGATACTACAGGGATTCAG
TGGCTGAGGAGGCAGCCGACTTGGATGGAGAAATTGACTTGTCCGCATGTTACGATGTCACAGAGTATCCAGTTCAGAGAAACTATGGCT
TCCAGATACATACAAAGGAGGGCGAGTTTACCCTGTCGGCCATGACATCTGGGATTCGGCGGAACTGGATCCAGACCATCATGAAGCACG
TGCACCCGACCACTGCCCCGGATGTGACCAGCTCGTTGCCAGAGGAAAAAAACAAGAGCAGCTGCTCTTTTGAGACCTGCCCGAGGCCTA
CTGAGAAGCAAGAGGCAGAGCTGGGGGAGCCGGACCCTGAGCAGAAGAGGAGCCGCGCACGGGAGCGGAGGCGAGAGGGCCGCTCCAAGA
CCTTTGACTGGGCTGAGTTCCGTCCCATCCAGCAGGCCCTGGCTCAGGAGCGGGTGGGCGGCGTGGGGCCTGCTGACACCCACGAGCCCC
TGCGCCCTGAGGCGGAGCCTGGGGAGCTGGAGCGGGAGCGTGCACGGAGGCGGGAGGAGCGCCGCAAGCGCTTCGGGATGCTCGACGCCA
CAGACGGGCCAGGCACTGAGGATGCAGCCCTGCGCATGGAGGTGGACCGGAGCCCAGGGCTGCCTATGAGCGACCTCAAAACGCATAACG
TCCACGTGGAGATTGAGCAGCGGTGGCATCAGGTGGAGACCACACCTCTCCGGGAAGAGAAGCAGGTGCCCATCGCCCCCGTCCACCTGT
CTTCTGAAGATGGGGGTGACCGGCTCTCCACACACGAGCTGACCTCTCTGCTCGAGAAGGAGCTGGAGCAGAGCCAGAAGGAGGCCTCAG
ACCTTCTGGAGCAGAACCGGCTCCTGCAGGACCAGCTGAGGGTGGCCCTGGGCCGGGAGCAGAGCGCCCGTGAGGGCTACGTGCTGCAGG
CCACGTGCGAGCGAGGGTTTGCAGCAATGGAAGAAACGCACCAGAAGAAGATTGAAGATCTCCAGAGGCAGCACCAGCGGGAGCTAGAGA
AACTTCGAGAAGAGAAAGACCGCCTCCTAGCCGAGGAGACAGCGGCCACCATCTCAGCCATCGAAGCCATGAAGAACGCCCACCGGGAGG
AAATGGAGCGGGAGCTGGAGAAGAGCCAGCGGTCCCAGATCAGCAGCGTCAACTCGGATGTTGAGGCCCTGCGGCGCCAGTACCTGGAGG
AGCTGCAGTCGGTGCAGCGGGAACTGGAGGTCCTCTCGGAGCAGTACTCGCAGAAGTGCCTGGAGAATGCCCATCTGGCCCAGGCGCTGG
AGGCCGAGCGGCAGGCCCTGCGGCAGTGCCAGCGTGAGAACCAGGAGCTCAATGCCCACAACCAGGAGCTGAACAACCGCCTGGCTGCAG
AGATCACACGGTTGCGGACGCTGCTGACTGGGGACGGCGGTGGGGAGGCCACTGGGTCACCCCTTGCACAGGGCAAGGATGCCTATGAAC
TAGAGGTCTTATTGCGGGTAAAGGAATCGGAAATACAGTACCTGAAACAGGAGATTAGCTCCCTCAAGGATGAGCTGCAGACGGCACTGC
GGGACAAGAAGTACGCAAGTGACAAGTACAAAGACATCTACACAGAGCTCAGCATCGCGAAGGCTAAGGCTGACTGTGACATCAGCAGGT
TGAAGGAGCAGCTCAAGGCTGCAACGGAAGCACTGGGGGAGAAGTCCCCTGACAGTGCCACGGTGTCCGGATATGATATAATGAAATCTA
AAAGCAACCCTGACTTCTTGAAGAAAGACAGATCCTGTGTCACCCGGCAACTCAGAAACATCAGGTCCAAGTCCGTAATTGAGCAGGTCT
CGTGGGATACCTGAAATGCACCCGCTTCCCGGCCCATGCAGGAGAGTCTGAAGGAAGGCCTGACGGTGCAAGAACGGTTGAAGCTCTTTG
AATCCAGGGACTTGAAGAAAGACTAGGTGTGTCCCATCCAAGTTGAGCACGCGCCTTCCCCAGCTTGCAGCAGCACACCCCAAGCGCTGC
TTTTCACCTGTACCTTTGTTTTATTATTATTATTATTATTGCTGTTGTTGTCATCGTTAACTGTGGGCATGGAATGCGTGAGGCTGGCTT
CTGGGTTGTCCACACCACTCTCTGCTGTGTTGACTTCCTGTTGTCTTCATCAAAGCTTTTTTCCGTGGTATTCTAAAATTAGGCCAGCAG
TGGGGGCTGGGAGGGCATCTGTGTTAGTCCTTTCCTGGCTGTGACCCGCCACACTCACTGTCAGTATTAAGGCCCAGCAGCCTGTTGATA
AGCTACCCTGTCTCACCATGTGCTGGTGTGGAAACGGGGCCCAGCCAGCACGCCTCAAGGTAGATGGAATCCCCACTGGTCAGAGAAAAA
GCTATGCGGACACTCCAGCTTGGCCTGGGTCACAGCACTGACTCCTCACCCGCTAGTCTGGCTGTTAAGAGGAGAAAGTGCACTGCCTTC
CAGCCCAGGAGGAGGACAGCATTTTGTATTTGTTCCACTGATGCAGCTTAGAACCACACCCCTGAGAGTCGTGGCAAACCTTTCACAACC

>57839_57839_1_NCOR1-MPRIP_NCOR1_chr17_16075117_ENST00000395851_MPRIP_chr17_16979024_ENST00000341712_length(amino acids)=1137AA_BP=153
MVRTSLLIMSSSGYPPNQGAFSTEQSRYPPHSVQYTFPNTRHQQEFAVPDYRSSHLEVSQASQLLQQQQQQQLRRRPSLLSEFHPGSDRP
QERRTSYEPFHPGPSPVDHDSLESKRPRLEQVSDSHFQRVSAAVLPLVHPLPEGLRASADAKKAKPIYGGWLLLAPDGTDFDNPVHRSRK
WQRRFFILYEHGLLRYALDEMPTTLPQGTINMNQCTDVVDGEGRTGQKFSLCILTPEKEHFIRAETKEIVSGWLEMLMVYPRTNKQNQKK
KRKVEPPTPQEPGPAKVAVTSSSSSSSSSSSIPSAEKVPTTKSTLWQEEMRTKDQPDGSSLSPAQSPSQSQPPAASSLREPGLESKEEES
AMSSDRMDCGRKVRVESGYFSLEKTKQDLKAEEQQLPPPLSPPSPSTPNHRRSQVIEKFEALDIEKAEHMETNAVGPSPSSDTRQGRSEK
RAFPRKRDFTNEAPPAPLPDASASPLSPHRRAKSLDRRSTEPSVTPDLLNFKKGWLTKQYEDGQWKKHWFVLADQSLRYYRDSVAEEAAD
LDGEIDLSACYDVTEYPVQRNYGFQIHTKEGEFTLSAMTSGIRRNWIQTIMKHVHPTTAPDVTSSLPEEKNKSSCSFETCPRPTEKQEAE
LGEPDPEQKRSRARERRREGRSKTFDWAEFRPIQQALAQERVGGVGPADTHEPLRPEAEPGELERERARRREERRKRFGMLDATDGPGTE
DAALRMEVDRSPGLPMSDLKTHNVHVEIEQRWHQVETTPLREEKQVPIAPVHLSSEDGGDRLSTHELTSLLEKELEQSQKEASDLLEQNR
LLQDQLRVALGREQSAREGYVLQATCERGFAAMEETHQKKIEDLQRQHQRELEKLREEKDRLLAEETAATISAIEAMKNAHREEMERELE
KSQRSQISSVNSDVEALRRQYLEELQSVQRELEVLSEQYSQKCLENAHLAQALEAERQALRQCQRENQELNAHNQELNNRLAAEITRLRT
LLTGDGGGEATGSPLAQGKDAYELEVLLRVKESEIQYLKQEISSLKDELQTALRDKKYASDKYKDIYTELSIAKAKADCDISRLKEQLKA

--------------------------------------------------------------
>57839_57839_2_NCOR1-MPRIP_NCOR1_chr17_16075117_ENST00000395851_MPRIP_chr17_16979024_ENST00000395804_length(transcript)=3434nt_BP=479nt
ATTGGCATTGATCTCACAGTCTGGTGAGGACTTCTTTACTGATAATGTCAAGTTCAGGTTATCCTCCCAACCAAGGAGCATTCAGCACAG
AACAAAGTCGTTATCCTCCTCACTCTGTCCAGTATACATTTCCCAACACCCGCCACCAGCAGGAGTTCGCAGTCCCTGATTATCGTTCCT
CTCATCTTGAAGTGAGTCAGGCATCACAGCTTTTGCAGCAACAGCAGCAGCAACAGCTTCGAAGGCGACCTTCCTTGCTTTCAGAATTTC
ACCCAGGTTCTGACAGGCCTCAAGAAAGGAGAACTAGTTATGAACCGTTTCATCCAGGCCCATCCCCAGTGGATCATGATTCACTGGAAT
CGAAGCGACCACGTCTGGAACAGGTTTCTGATTCTCATTTTCAGCGTGTCAGTGCTGCGGTTTTGCCTTTAGTGCACCCGCTGCCAGAAG
GGCTGAGGGCTTCTGCAGATGCTAAGAAGGCAAAACCCATTTATGGCGGTTGGCTGCTCCTGGCTCCAGATGGGACCGACTTTGACAACC
CAGTGCACCGGTCTCGGAAATGGCAGCGACGGTTCTTCATCCTTTACGAGCACGGCCTCTTGCGCTACGCCCTGGATGAGATGCCCACGA
CCCTTCCTCAGGGCACCATCAACATGAACCAGTGCACAGATGTGGTGGATGGGGAGGGCCGCACGGGCCAGAAGTTCTCCCTGTGTATTC
TGACGCCTGAGAAGGAGCATTTCATCCGGGCGGAGACCAAGGAGATCGTCAGTGGGTGGCTGGAGATGCTCATGGTCTATCCCCGGACCA
ACAAGCAGAATCAGAAGAAGAAACGGAAAGTGGAGCCCCCCACACCACAGGAGCCTGGGCCTGCCAAGGTGGCTGTTACCAGCAGCAGCA
GCAGCAGCAGCAGCAGCAGCAGCATCCCCAGTGCTGAGAAAGTCCCCACCACCAAGTCCACACTCTGGCAGGAAGAAATGAGGACCAAGG
ACCAGCCAGATGGCAGCAGCCTGAGTCCAGCTCAGAGTCCCAGCCAGAGCCAGCCTCCTGCTGCCAGCTCCCTGCGGGAACCTGGGCTAG
AGAGCAAAGAAGAGGAGAGCGCCATGAGTAGCGACCGCATGGACTGTGGCCGCAAAGTCCGGGTGGAGAGCGGCTACTTCTCTCTGGAGA
AGACCAAACAGGACTTGAAGGCTGAAGAACAGCAGCTGCCCCCGCCGCTCTCCCCTCCCAGCCCCAGCACCCCCAACCACAGGAGGTCCC
AGGTGATTGAAAAGTTTGAGGCCTTGGACATTGAGAAGGCAGAGCACATGGAGACCAATGCAGTGGGGCCCTCACCATCCAGCGACACAC
GCCAGGGCCGCAGCGAGAAGAGGGCGTTCCCTAGGAAGCGGGACTTCACCAATGAAGCCCCCCCAGCTCCTCTCCCAGACGCCTCGGCTT
CCCCCCTGTCTCCACACCGAAGAGCCAAGTCACTGGACAGGAGGTCCACGGAGCCCTCCGTGACGCCCGACCTGCTGAATTTCAAGAAAG
GCTGGCTGACTAAGCAGTATGAGGACGGCCAGTGGAAGAAACACTGGTTTGTCCTCGCCGATCAAAGCCTGAGATACTACAGGGATTCAG
TGGCTGAGGAGGCAGCCGACTTGGATGGAGAAATTGACTTGTCCGCATGTTACGATGTCACAGAGTATCCAGTTCAGAGAAACTATGGCT
TCCAGATACATACAAAGGAGGGCGAGTTTACCCTGTCGGCCATGACATCTGGGATTCGGCGGAACTGGATCCAGACCATCATGAAGCACG
TGCACCCGACCACTGCCCCGGATGTGACCAGCTCGTTGCCAGAGGAAAAAAACAAGAGCAGCTGCTCTTTTGAGACCTGCCCGAGGCCTA
CTGAGAAGCAAGAGGCAGAGCTGGGGGAGCCGGACCCTGAGCAGAAGAGGAGCCGCGCACGGGAGCGGAGGCGAGAGGGCCGCTCCAAGA
CCTTTGACTGGGCTGAGTTCCGTCCCATCCAGCAGGCCCTGGCTCAGGAGCGGGTGGGCGGCGTGGGGCCTGCTGACACCCACGAGCCCC
TGCGCCCTGAGGCGGAGCCTGGGGAGCTGGAGCGGGAGCGTGCACGGAGGCGGGAGGAGCGCCGCAAGCGCTTCGGGATGCTCGACGCCA
CAGACGGGCCAGGCACTGAGGATGCAGCCCTGCGCATGGAGGTGGACCGGAGCCCAGGGCTGCCTATGAGCGACCTCAAAACGCATAACG
TCCACGTGGAGATTGAGCAGCGGTGGCATCAGGTGGAGACCACACCTCTCCGGGAAGAGAAGCAGGTGCCCATCGCCCCCGTCCACCTGT
CTTCTGAAGATGGGGGTGACCGGCTCTCCACACACGAGCTGACCTCTCTGCTCGAGAAGGAGCTGGAGCAGAGCCAGAAGGAGGCCTCAG
ACCTTCTGGAGCAGAACCGGCTCCTGCAGGACCAGCTGAGGGTGGCCCTGGGCCGGGAGCAGAGCGCCCGTGAGGGCTACGTGCTGCAGG
CCACGTGCGAGCGAGGGTTTGCAGCAATGGAAGAAACGCACCAGAAGAAGATTGAAGATCTCCAGAGGCAGCACCAGCGGGAGCTAGAGA
AACTTCGAGAAGAGAAAGACCGCCTCCTAGCCGAGGAGACAGCGGCCACCATCTCAGCCATCGAAGCCATGAAGAACGCCCACCGGGAGG
AAATGGAGCGGGAGCTGGAGAAGAGCCAGCGGTCCCAGATCAGCAGCGTCAACTCGGATGTTGAGGCCCTGCGGCGCCAGTACCTGGAGG
AGCTGCAGTCGGTGCAGCGGGAACTGGAGGTCCTCTCGGAGCAGTACTCGCAGAAGTGCCTGGAGAATGCCCATCTGGCCCAGGCGCTGG
AGGCCGAGCGGCAGGCCCTGCGGCAGTGCCAGCGTGAGAACCAGGAGCTCAATGCCCACAACCAGGAGCTGAACAACCGCCTGGCTGCAG
AGATCACACGGTTGCGGACGCTGCTGACTGGGGACGGCGGTGGGGAGGCCACTGGGTCACCCCTTGCACAGGGCAAGGATGCCTATGAAC
TAGAGGTCTTATTGCGGGTAAAGGAATCGGAAATACAGTACCTGAAACAGGAGATTAGCTCCCTCAAGGATGAGCTGCAGACGGCACTGC
GGGACAAGAAGTACGCAAGTGACAAGTACAAAGACATCTACACAGAGCTCAGCATCGCGAAGGCTAAGGCTGACTGTGACATCAGCAGGT
TGAAGGAGCAGCTCAAGGCTGCAACGGAAGCACTGGGGGAGAAGTCCCCTGACAGTGCCACGGTGTCCGGATATGATATAATGAAATCTA
AAAGCAACCCTGACTTCTTGAAGAAAGACAGATCCTGTGTCACCCGGCAACTCAGAAACATCAGGTCCAAGTCCGTAATTGAGCAGGTCT

>57839_57839_2_NCOR1-MPRIP_NCOR1_chr17_16075117_ENST00000395851_MPRIP_chr17_16979024_ENST00000395804_length(amino acids)=1138AA_BP=153
MVRTSLLIMSSSGYPPNQGAFSTEQSRYPPHSVQYTFPNTRHQQEFAVPDYRSSHLEVSQASQLLQQQQQQQLRRRPSLLSEFHPGSDRP
QERRTSYEPFHPGPSPVDHDSLESKRPRLEQVSDSHFQRVSAAVLPLVHPLPEGLRASADAKKAKPIYGGWLLLAPDGTDFDNPVHRSRK
WQRRFFILYEHGLLRYALDEMPTTLPQGTINMNQCTDVVDGEGRTGQKFSLCILTPEKEHFIRAETKEIVSGWLEMLMVYPRTNKQNQKK
KRKVEPPTPQEPGPAKVAVTSSSSSSSSSSSIPSAEKVPTTKSTLWQEEMRTKDQPDGSSLSPAQSPSQSQPPAASSLREPGLESKEEES
AMSSDRMDCGRKVRVESGYFSLEKTKQDLKAEEQQLPPPLSPPSPSTPNHRRSQVIEKFEALDIEKAEHMETNAVGPSPSSDTRQGRSEK
RAFPRKRDFTNEAPPAPLPDASASPLSPHRRAKSLDRRSTEPSVTPDLLNFKKGWLTKQYEDGQWKKHWFVLADQSLRYYRDSVAEEAAD
LDGEIDLSACYDVTEYPVQRNYGFQIHTKEGEFTLSAMTSGIRRNWIQTIMKHVHPTTAPDVTSSLPEEKNKSSCSFETCPRPTEKQEAE
LGEPDPEQKRSRARERRREGRSKTFDWAEFRPIQQALAQERVGGVGPADTHEPLRPEAEPGELERERARRREERRKRFGMLDATDGPGTE
DAALRMEVDRSPGLPMSDLKTHNVHVEIEQRWHQVETTPLREEKQVPIAPVHLSSEDGGDRLSTHELTSLLEKELEQSQKEASDLLEQNR
LLQDQLRVALGREQSAREGYVLQATCERGFAAMEETHQKKIEDLQRQHQRELEKLREEKDRLLAEETAATISAIEAMKNAHREEMERELE
KSQRSQISSVNSDVEALRRQYLEELQSVQRELEVLSEQYSQKCLENAHLAQALEAERQALRQCQRENQELNAHNQELNNRLAAEITRLRT
LLTGDGGGEATGSPLAQGKDAYELEVLLRVKESEIQYLKQEISSLKDELQTALRDKKYASDKYKDIYTELSIAKAKADCDISRLKEQLKA

--------------------------------------------------------------
>57839_57839_3_NCOR1-MPRIP_NCOR1_chr17_16075117_ENST00000395851_MPRIP_chr17_16979024_ENST00000395811_length(transcript)=11227nt_BP=479nt
ATTGGCATTGATCTCACAGTCTGGTGAGGACTTCTTTACTGATAATGTCAAGTTCAGGTTATCCTCCCAACCAAGGAGCATTCAGCACAG
AACAAAGTCGTTATCCTCCTCACTCTGTCCAGTATACATTTCCCAACACCCGCCACCAGCAGGAGTTCGCAGTCCCTGATTATCGTTCCT
CTCATCTTGAAGTGAGTCAGGCATCACAGCTTTTGCAGCAACAGCAGCAGCAACAGCTTCGAAGGCGACCTTCCTTGCTTTCAGAATTTC
ACCCAGGTTCTGACAGGCCTCAAGAAAGGAGAACTAGTTATGAACCGTTTCATCCAGGCCCATCCCCAGTGGATCATGATTCACTGGAAT
CGAAGCGACCACGTCTGGAACAGGTTTCTGATTCTCATTTTCAGCGTGTCAGTGCTGCGGTTTTGCCTTTAGTGCACCCGCTGCCAGAAG
GGCTGAGGGCTTCTGCAGATGCTAAGAAGGCAAAACCCATTTATGGCGGTTGGCTGCTCCTGGCTCCAGATGGGACCGACTTTGACAACC
CAGTGCACCGGTCTCGGAAATGGCAGCGACGGTTCTTCATCCTTTACGAGCACGGCCTCTTGCGCTACGCCCTGGATGAGATGCCCACGA
CCCTTCCTCAGGGCACCATCAACATGAACCAGTGCACAGATGTGGTGGATGGGGAGGGCCGCACGGGCCAGAAGTTCTCCCTGTGTATTC
TGACGCCTGAGAAGGAGCATTTCATCCGGGCGGAGACCAAGGAGATCGTCAGTGGGTGGCTGGAGATGCTCATGGTCTATCCCCGGACCA
ACAAGCAGAATCAGAAGAAGAAACGGAAAGTGGAGCCCCCCACACCACAGGAGCCTGGGCCTGCCAAGGTGGCTGTTACCAGCAGCAGCA
GCAGCAGCAGCAGCAGCAGCAGCATCCCCAGTGCTGAGAAAGTCCCCACCACCAAGTCCACACTCTGGCAGGAAGAAATGAGGACCAAGG
ACCAGCCAGATGGCAGCAGCCTGAGTCCAGCTCAGAGTCCCAGCCAGAGCCAGCCTCCTGCTGCCAGCTCCCTGCGGGAACCTGGGCTAG
AGAGCAAAGAAGAGGAGAGCGCCATGAGTAGCGACCGCATGGACTGTGGCCGCAAAGTCCGGGTGGAGAGCGGCTACTTCTCTCTGGAGA
AGACCAAACAGGACTTGAAGGCTGAAGAACAGCAGCTGCCCCCGCCGCTCTCCCCTCCCAGCCCCAGCACCCCCAACCACAGGAGGTCCC
AGGTGATTGAAAAGTTTGAGGCCTTGGACATTGAGAAGGCAGAGCACATGGAGACCAATGCAGTGGGGCCCTCACCATCCAGCGACACAC
GCCAGGGCCGCAGCGAGAAGAGGGCGTTCCCTAGGAAGCGGGACTTCACCAATGAAGCCCCCCCAGCTCCTCTCCCAGACGCCTCGGCTT
CCCCCCTGTCTCCACACCGAAGAGCCAAGTCACTGGACAGGAGGTCCACGGAGCCCTCCGTGACGCCCGACCTGCTGAATTTCAAGAAAG
GCTGGCTGACTAAGCAGTATGAGGACGGCCAGTGGAAGAAACACTGGTTTGTCCTCGCCGATCAAAGCCTGAGATACTACAGGGATTCAG
TGGCTGAGGAGGCAGCCGACTTGGATGGAGAAATTGACTTGTCCGCATGTTACGATGTCACAGAGTATCCAGTTCAGAGAAACTATGGCT
TCCAGATACATACAAAGGAGGGCGAGTTTACCCTGTCGGCCATGACATCTGGGATTCGGCGGAACTGGATCCAGACCATCATGAAGCACG
TGCACCCGACCACTGCCCCGGATGTGACCAGCTCGTTGCCAGAGGAAAAAAACAAGAGCAGCTGCTCTTTTGAGACCTGCCCGAGGCCTA
CTGAGAAGCAAGAGGCAGAGCTGGGGGAGCCGGACCCTGAGCAGAAGAGGAGCCGCGCACGGGAGCGGAGGCGAGAGGGCCGCTCCAAGA
CCTTTGACTGGGCTGAGTTCCGTCCCATCCAGCAGGCCCTGGCTCAGGAGCGGGTGGGCGGCGTGGGGCCTGCTGACACCCACGAGCCCC
TGCGCCCTGAGGCGGAGCCTGGGGAGCTGGAGCGGGAGCGTGCACGGAGGCGGGAGGAGCGCCGCAAGCGCTTCGGGATGCTCGACGCCA
CAGACGGGCCAGGCACTGAGGATGCAGCCCTGCGCATGGAGGTGGACCGGAGCCCAGGGCTGCCTATGAGCGACCTCAAAACGCATAACG
TCCACGTGGAGATTGAGCAGCGGTGGCATCAGGTGGAGACCACACCTCTCCGGGAAGAGAAGCAGGTGCCCATCGCCCCCGTCCACCTGT
CTTCTGAAGATGGGGGTGACCGGCTCTCCACACACGAGCTGACCTCTCTGCTCGAGAAGGAGCTGGAGCAGAGCCAGAAGGAGGCCTCAG
ACCTTCTGGAGCAGAACCGGCTCCTGCAGGACCAGCTGAGGGTGGCCCTGGGCCGGGAGCAGAGCGCCCGTGAGGGCTACGTGCTGCAGG
CCACGTGCGAGCGAGGGTTTGCAGCAATGGAAGAAACGCACCAGAAGAAGATTGAAGATCTCCAGAGGCAGCACCAGCGGGAGCTAGAGA
AACTTCGAGAAGAGAAAGACCGCCTCCTAGCCGAGGAGACAGCGGCCACCATCTCAGCCATCGAAGCCATGAAGAACGCCCACCGGGAGG
AAATGGAGCGGGAGCTGGAGAAGAGCCAGCGGTCCCAGATCAGCAGCGTCAACTCGGATGTTGAGGCCCTGCGGCGCCAGTACCTGGAGG
AGCTGCAGTCGGTGCAGCGGGAACTGGAGGTCCTCTCGGAGCAGTACTCGCAGAAGTGCCTGGAGAATGCCCATCTGGCCCAGGCGCTGG
AGGCCGAGCGGCAGGCCCTGCGGCAGTGCCAGCGTGAGAACCAGGAGCTCAATGCCCACAACCAGGAGCTGAACAACCGCCTGGCTGCAG
AGATCACACGGTTGCGGACGCTGCTGACTGGGGACGGCGGTGGGGAGGCCACTGGGTCACCCCTTGCACAGGGCAAGGATGCCTATGAAC
TAGAGGTCTTATTGCGGGTAAAGGAATCGGAAATACAGTACCTGAAACAGGAGATTAGCTCCCTCAAGGATGAGCTGCAGACGGCACTGC
GGGACAAGAAGTACGCAAGTGACAAGTACAAAGACATCTACACAGAGCTCAGCATCGCGAAGGCTAAGGCTGACTGTGACATCAGCAGGT
TGAAGGAGCAGCTCAAGGCTGCAACGGAAGCACTGGGGGAGAAGTCCCCTGACAGTGCCACGGTGTCCGGATATGATATAATGAAATCTA
AAAGCAACCCTGACTTCTTGAAGAAAGACAGATCCTGTGTCACCCGGCAACTCAGAAACATCAGGTCCAAGAGTCTGAAGGAAGGCCTGA
CGGTGCAAGAACGGTTGAAGCTCTTTGAATCCAGGGACTTGAAGAAAGACTAGGTGTGTCCCATCCAAGTTGAGCACGCGCCTTCCCCAG
CTTGCAGCAGCACACCCCAAGCGCTGCTTTTCACCTGTACCTTTGTTTTATTATTATTATTATTATTGCTGTTGTTGTCATCGTTAACTG
TGGGCATGGAATGCGTGAGGCTGGCTTCTGGGTTGTCCACACCACTCTCTGCTGTGTTGACTTCCTGTTGTCTTCATCAAAGCTTTTTTC
CGTGGTATTCTAAAATTAGGCCAGCAGTGGGGGCTGGGAGGGCATCTGTGTTAGTCCTTTCCTGGCTGTGACCCGCCACACTCACTGTCA
GTATTAAGGCCCAGCAGCCTGTTGATAAGCTACCCTGTCTCACCATGTGCTGGTGTGGAAACGGGGCCCAGCCAGCACGCCTCAAGGTAG
ATGGAATCCCCACTGGTCAGAGAAAAAGCTATGCGGACACTCCAGCTTGGCCTGGGTCACAGCACTGACTCCTCACCCGCTAGTCTGGCT
GTTAAGAGGAGAAAGTGCACTGCCTTCCAGCCCAGGAGGAGGACAGCATTTTGTATTTGTTCCACTGATGCAGCTTAGAACCACACCCCT
GAGAGTCGTGGCAAACCTTTCACAACCTGGAAAATGTTGAAAGCAACCATTCCTATTTTTGTTTGTTTTTTATTAAATCTTGCACAAAAT
CCCCGGCCCCTCTCCTTCCTTCCTTCCTTCCTTCCTCCGCTCGTTCCTTTCTTGGTCTCCAGTAACCCTGGTCTTTTCATAACTGCTCGA
GATTGTTGACCTGCAGCCCAGGTTTCAGACTCTGATTGCAAAAAACAAATGAATTCCCCCCAGGAATCATTCAAAATGGGGGAAGGTTTG
GGGGTTTGGGTTTTTTTTTTACCTTTTGGAAAAGAAACCGTCACATTGCTTTGGAAAAGGTTGAGAGGAGACCCCTGTTAAGTCAAGAAG
AAAGTACAGAGGATGTCAGAATCTGATGAGAACAGCACATTAGTGTTTATTGAGACTCCGATCTTAACTCTCATTTAATTAATCTGAGCT
CTGAAAACCTATCTTGCAGCATTTATCTTTAAAAGAGCCTGGTTAAAGTAAACCTATACTAACAATTTTGCTTTTTCTAACAGTTTGAGG
AAGACCTTTTTAACCACCACAAAACATTCTATGGCAATTCTTGAAAATCTCTTAAATTGGAGTCTATTATGGCCCCATGAAAACCATTAA
TCCCATTAAGATAGGGAGTATAAACCCCTGGCTGGTGGAACAGGTTCTGCTACTTTAGGAGCAAGGTGGGGTGTGAGTAGATGGTTTTCA
TGCCAAGAACATGCTTTCACTTTGTATTCATGCTTGTGTTGGTGTGATGGTCTCTGTGGGTGGGTGGATGCTTTGGGCGTTGAAATCTAG
AAATCCTGTTGCTCAGTTTCTAGATGAAGTCATGAGCAAGGCCATCAGTGGAGCTCTGGCCCCGCCCCCAATGTGCAGAAGGGCCGGGAG
CAAGGCCTGGAGTTTTCATGTGTTTTCAGACCCAGGTTTAGGTGCTCTCTTCTCACTGAAATAACTAAGTGCTCTCCACTGGCATCGAGC
CCTTTCCACAAGTTTTTAAGGCTCTTAACCCACACTTTCACTCCTCTGCTACTAGTCTTCAGTGTTGTTAACAGCAAGAGAAAATTGGGT
TTGTTTAAAAATCTACTTCTCTGAGGTGGCACAGTTGCGTAGCTGTAGTCCCAGCTACTCAGGAGGCTGAGGTAGTAGGATTGCTTGAGC
CCGGGAGGTCGAGGCTGCAATCAGTCATGATCGTGTCACTGCACTCCAGCCTGGGTGACAAAGCAAGGCCCCATATCAGATATAGATATA
CTTATCAGACCCCCCCTGACCATTTAGATTGGCAGTGCTTTGAGAAATGCACTATGACCTTTCTGTGTCAATGGGAATATACAGAAGGAA
CATTCGGGACCCCGCTGTCCCCCACAGCCTCATTGTTGTCTCCAGGACACTGCTGGGTCACACGAATGCTCCAGGACAGACAGGGACCTG
GAGTGCATCAGGATCTGACCAGATAGGAGTTTTTGCCTCGTGTCTGGGTGCTACGATTTTGTGCCGTTCTCTGAGGTCCACCACCTGCCC
TTCCTGGCATGGTTTCCTTCGTGACCATCCCTGCTGCCCCTGGGGGTGGACCCCACTGGCCCTTCTGCAGACAGCTCCCTGCCTTCTGCC
CTCCAGGGGGTTCTGGCCAGAGTCCATGCTTGGAGACAGGATCATCTGCCTTCAGCCCTCACAGTGCTTTAAATTAAAGCAAGTTTGCCC
ATAGGACAAAAGAGCATTTGATTCCCTTTTTTCTGTCACATATCCCTTGAGGCTGGACTTCAGGAATCCTGGAAAATTAATATGAGTGCA
GCATGTGAGGGGTCAGAGACAGGCCAGCAGGGCGTCTGCATTCCTCCCTGCCACAGGTCTCTCCCCAGAGGCTGGTTTAGTGTAGGGTAT
TGCCAGGAAACGGACTGAGGCTGCTTTGCTAAGAGCTCCTGAAAATGCCCTGGGCCTGTCCTGGCGTTTCTGAAGAGCCCTCATACAGGG
ACAGCCACCATCTGGGTCAAGGAAGTCTGGGTTCCCTGCTGGTGGGCTCCATCCTGCGATGGAGTGAACCAGGCGAGAAAGGATGACGAT
GTTCTTCATGTTGCACCTGGACATGCCCCAGGAACAGAGACTTGCCCAGGTGGCAACACTGGCACAGATGTTGACGGCTGCCCAACTGGT
GCCACACTGAGCAGGGAGCCTTGTGCTGCACAGGGCTGGGCCCTCTCTCCAGTTTCCTTCCTGCAGGCATCCAAATACCCTGGAAGGGAT
TTAACCCCTGAATTCCAGAGGGAAGAAAGAAGAACAGTGAAGAAGTAGAACTGGTTTCTGTATGGGGAGAGGAAAGTCTTAGGGACAGCT
GCAGGCGGGGTCTCAGGCTGCTCCTTGGCACCAGCTACACAGTAGTGAGCTTTCCCAGCTTTACCGATGAGGAAGAAGTTCAAATAGATA
GACTTCAGCATTTTAATTATTTTCCTATAAATGTATTTATGTGTAGTATGCTAGCACCAGCCAGTAAGCTGTGCCACACATATGAATGGG
AAAGCGAGGCAGTTGTGCTCGTGTGAGTTTCTGCAGGCTTGTGGGTAATTACCTTGTGTGCACGCCTGCACGTGCAGAATAGTCACTTTC
TGCTGGTCAGTTTCTTTATCCACCCATGGTGCCCCAGCCCCAGGCAGGTGTGGAGACCAGCATTTCAGAGGACGCGCTGTCCACAGCCTC
CCGGGTCTGAGTGGATCATTGGGCAGGGGTGGAGACAGTGCGCTGCCCTCTGAGCTGGAAGCCTGTGCTTCAGGGAGTCATAATGGGCCT
GTGCTAAGTGGGTGATGCAGTGGACATCCCAGGGCGACTAGAGGTGGCAGTATCGCGAATTTGCAGGTTTATTGAACAAGAGGTAACATC
GGAGAGGATCTTGCCTTCGGATTCAGCAAGTATGAAGGCAGAAGAGCATGGAGAGCAAGGCCCCACAGCCTGCTTAGTGAGTTGGAAGGC
CCAGCAAGAACCTGTTTCTGCAGCAGCCACCAGCTCCCATCACCCCTTGACCCTCCAGCTCATGCTGGAGAAGAGGGAATTTTGGCTGTT
TAAAGAACACAGTTGTGAATCTCAGAATGTGCCTGAAAGGAATACTGACAGATAAGGCCGGAAACAAAACTGATGGCTTGAAAAACATTT
TTATGGAATGTATTTACTATCATTTTGTTTTACTATAGAGGTAGATGGGACTCTTAACTTTTGGGTACATGGAAACATGCTGAAAACTGA
ACACAATCCTGATCATCACTCCTGCCTGGCTGTCTCCTGGGAGGCTGCCGGGTGCCACGGAGCTGGGACACAGCAGAGCCCGCTAGGTGT
TGCAGGGCCCTGGAGGCCAAGGCCACCCTGTGTGGGGTCCCTGTTGGCAGCCAGGTCCCTACACAAACAAGTAATCCTGTTTGGCCTCCT
AGGTTTTGCATATGACCTGCAGCCTAATTTGGGGTGTAGGGGAAGCTCTGCTGGCCCCTGCTCCTTTGTATGTTGGGTGACTTTAATGGC
TGGCCACATACCCCTTTCTCCCAGCTACTCATTCACTGACTTGGGTAAGTTCTAAGACAGTTCGCACTTAGAAAAGAATGTGACACATCA
ACATTAACTTTTCCTGAAAAGAAGAGTTTGCCTAACATGGTCCTAAAGAAGCTTGGAATTTATAAGACTTTCCTTTATAAGATATAGTGG
GGGTTTTTTTGGGTGGAGGGGGGTTGTTTTTTGTTTTTTGTTTTCAAGACAGAGTCTCGCTCTGTTGTCCAGGCTGGAGTGTAGTGGCAT
GATCTCGGCTCACTGCAACCTCTGCCTCCCAGGTTCATGCCATTCTCCTGCCTCAGCCTCCCGAGTAGCTGGGACTACAGGTGTCTGCCG
CCACGCCTGGCTAATTTTTTTGTATTTTTAGTAGAGACGGGGTTTCACCATGTTGGTCAGGATGGTCTCGATTTCCTGACCTCGTGATCC
GCCTGTCTCGGCCTCCCAAAGTGCTGGGATTACAGGCGTGAGCCACCACGCCTGGCCTATAAGATACGGTAAAAAAAAAAAACTGTGACC
CCTTTGTCACTAAGGGAGAAAGAAATTAAGTATTGTCAAAGTTCTATAAAGAATGGAAATGTATGATATTATACTTCAAAGGAATTTGAT
GTTGAAATTTTAAAGAAAATTTGTCATGTTGATGAGAAGCTTCACTTTCCTGGGAACTTCATTCGTTTTAGGGCATGAGATAAAAGTCCT
GGCTAGGGGAGCCATAGGTCTGTTGTACAAGGAATTTGCTTTCTAAACAAGTTGTAACTTGCCCTAAGGTCCCTGTTGGAGCACTAAGAG
GTGACACAGGCCAGAGACAACGTTTCGTTTCCCCTTCCCTGCAAGCTGGGATCAGCCCTGTGTTTTCTCCTTTCAGCTGAAGTGAGCGAA
GGTTCTCAGTGCTGGCAAAAGAGCCCACTTTCTAAAAGGACTTGGGAAGAAAGCTGCTGGGAACTTGCTTATTAAAAAGTTCCTTAGAAT
TAAGGTATCTACCCACTGTTTTCGCACCTTTCACCTTCCTGGGCTTTCCTGCCCTCCAGCATTCTTCTCTAGAGAGGTTCCTAGCCCGCT
CAGCGCGAGCGTCTCCAGTAGGTAATAGCAGCTGAACGTGGGTTTTCCACGGACTTCAGGCTTGGAGGTGCCATATACAAGCACACTTCT
TCCTTCCCCTGGCTTCTCCATGCCACCACCCACTTTAAAGATGTAAACTCAGTAGATTTTTCATCCAGTGAACGGTCATCTTCACATCGA
AAGGTGAAGGCCACCACTGTTCTCAATGCCAAGCAACAGAACGTTCTGAGATGGCCGTTCTTCCTTGCACAGCAGCTACGGCAGGTTGTT
CTGCAGCCACCCCTTAGAGGGGGCTCTTCGTTTTACCTTTGTACAGTTCTTGTGTTTACACATTTGGGCCAAACAGCTTTCAGCAAGGGC
ATGTGTCCACAGCTGATGGGCAGTTAAGAACCAGCCTGAGCTGAAGGCTAGTAATACCGTGCTGTAGGCTCTTTAAAAGGAAAGCCTGGC
ATAAACCCAGCATGGAAAGGAACATTATCAGTTATCTCAAATTTTGTCTGCCAGGGACAAGACCCTGTTCATTCTTTTGCCCTTTTCAGA
ACTGTGAGCTTCAAGTATTCTTGCTTCTCTGTAAAGGGAAGACATCTCCCTTCTCTGAAATCCTTCAACAAAAGAAAAGGCTCTTGGCAG
GGTAGGGGAGTCAGTAGCTCAACACTAGATCATCCCTAGAGATGGGGCAAGTTTCTGTCTGAACACGTCTTGGGTCCGAGTCCTTAGGTG
TTCGGATGCAGTACTTTGTGAATACTTAAGCTACTGCATGCTTGGTGTAGCTTGCAATTTCTCTGTATTTAAAAGCAGCTGTGTTTATTT
TCTTCAAAATAACCTGTATATTATTTAGAGCAAGCAATGTAAATATTACTGAGAAGTTACTGCAGGGATTTTTGTGACAGAGTTTGTATG
GGTTTTTAAAAAAATCTTAGACACCCCTTTTTAAGATGGGGAGAACAGGGTTGACTGCACCGTTGAAGCCCGCCCAGCATTATAAGGAAA
TGTTTTTAATGACTGCTGCATCTTTGTAAAACGTTTGGTCATCTAACAGATGGTTTTAAAGTGTACAATATCCAAAATAACGATAGCCCT
GTATCCATACATTGTTTCATTGAAAGAATTCTCTATTGCCTCTTCTTGGTAGAGCCAGAGTCCTTAAGGAAAATCAGGAAAATTAAGAAA
ATGATGGTGCCATCTTGACCAGACTTCTGCACAGTAATTTAACGCTATCCTAGGGAGACTTGGTTGAAGGCACAGTTCTGGGATCAGGGT
CTAAATGTGCAGTTTCTGAGAACCTTCAAGACCACTCACTGGGCAGGGCTCTGTGGAGCACTGGAGCTGTTTGGATTCCCCAGCCCTTTG
GTCATATCCTGGAATTCCGTGGAGGCTGCAGAACTTAGATGCAGCTGTTTTTTACAGCACCTATTTTTGTCAGATTGGTAAGGAAACACT
GAGTCACAGAATACTTAAGAATTGGAGACTCCAGTAATGTAGGATGGCCTGAGAGGACGTCCAAGTCCCAAGGGGTGGACACGGCATGTT
CCTCGGGCACAGCCTCAGTGGGGGCCTTCCCCAGGCGCAGCTCGGCCACCTGAGGAAAGGGTGTTTCGGAGGCGCAGCCACACACACAGC
GCTGGCAGCCTCACGGTCACGCCCATCACTCCCTGCCCCCCACTGCCCTTGAGAAGTTAGTGGTGTCACATCCTTAGTTTTATAGACAGC
TAGGAATAGATTGTGAAGAACACTCAGTTCACTACTGTGTTACATTTATATCACAAGCTTCAATTAAAATGGATTTTAAAGGATTTTAGG
ATTTACCTTTAGTATTAACAACGTATCTACTGACATACTGTTAGGATTCAAAACCAGTTAAGTATAAGAATTACTTCATGTGGTTTTCCT
AGGGTACAATTTATAAAAGGTAGAAAGCATCCAAGTGGCTCCTCAACAATTACAATTCTTAATGATTTTTCTCACAGCTGTGCCCTTCTG
TCAGGGTCAGTGTCAAAATTCGTTATCAAAGGCAAAACCTACTGTGCCAAGCTGGGGCGCTATATGTGAACGGAGTGGAAATGCTTCAGT
CACCTCTGCCGCAGCTTGTGATTCCAGCAGTTCTCACAAACGTTCTGTCACATGATGAAAAGAAGCAGCTTGTATAATTCCAACTGGTGT
TTCATTTCTGTTCTAATGCTAAGTGGTAACGCTTAACAAACAGACTAAAAGCTGTGTGCAGAAGAAAGGGCTGAATGAGTACCGCCTCCC
TAGGTTCCAGCACAGCGCTCGGGTCTAAGAAGTAGAGCCCCGGGGTAGGGTGGGCCATCCACTGTCAGGCCAGTGTCTCAAGAAAGCCTG
ACCAGCTGAGCTGCTGCTTTTTTTTTGGGGGGGGGGGGGGGAGGGGCGTCTTGAGGCTTTTTTTTTTTTTACAAAGTTAGTTTGTGATCA
ACGATTCACTACAATTGAAGTGTTACTTTGTCAGAATATTTATTCCTTTGTGTGACATGCTAGATTCCCTGGATGTAGCTGATCATTTTT

>57839_57839_3_NCOR1-MPRIP_NCOR1_chr17_16075117_ENST00000395851_MPRIP_chr17_16979024_ENST00000395811_length(amino acids)=1150AA_BP=153
MVRTSLLIMSSSGYPPNQGAFSTEQSRYPPHSVQYTFPNTRHQQEFAVPDYRSSHLEVSQASQLLQQQQQQQLRRRPSLLSEFHPGSDRP
QERRTSYEPFHPGPSPVDHDSLESKRPRLEQVSDSHFQRVSAAVLPLVHPLPEGLRASADAKKAKPIYGGWLLLAPDGTDFDNPVHRSRK
WQRRFFILYEHGLLRYALDEMPTTLPQGTINMNQCTDVVDGEGRTGQKFSLCILTPEKEHFIRAETKEIVSGWLEMLMVYPRTNKQNQKK
KRKVEPPTPQEPGPAKVAVTSSSSSSSSSSSIPSAEKVPTTKSTLWQEEMRTKDQPDGSSLSPAQSPSQSQPPAASSLREPGLESKEEES
AMSSDRMDCGRKVRVESGYFSLEKTKQDLKAEEQQLPPPLSPPSPSTPNHRRSQVIEKFEALDIEKAEHMETNAVGPSPSSDTRQGRSEK
RAFPRKRDFTNEAPPAPLPDASASPLSPHRRAKSLDRRSTEPSVTPDLLNFKKGWLTKQYEDGQWKKHWFVLADQSLRYYRDSVAEEAAD
LDGEIDLSACYDVTEYPVQRNYGFQIHTKEGEFTLSAMTSGIRRNWIQTIMKHVHPTTAPDVTSSLPEEKNKSSCSFETCPRPTEKQEAE
LGEPDPEQKRSRARERRREGRSKTFDWAEFRPIQQALAQERVGGVGPADTHEPLRPEAEPGELERERARRREERRKRFGMLDATDGPGTE
DAALRMEVDRSPGLPMSDLKTHNVHVEIEQRWHQVETTPLREEKQVPIAPVHLSSEDGGDRLSTHELTSLLEKELEQSQKEASDLLEQNR
LLQDQLRVALGREQSAREGYVLQATCERGFAAMEETHQKKIEDLQRQHQRELEKLREEKDRLLAEETAATISAIEAMKNAHREEMERELE
KSQRSQISSVNSDVEALRRQYLEELQSVQRELEVLSEQYSQKCLENAHLAQALEAERQALRQCQRENQELNAHNQELNNRLAAEITRLRT
LLTGDGGGEATGSPLAQGKDAYELEVLLRVKESEIQYLKQEISSLKDELQTALRDKKYASDKYKDIYTELSIAKAKADCDISRLKEQLKA

--------------------------------------------------------------
>57839_57839_4_NCOR1-MPRIP_NCOR1_chr17_16075117_ENST00000395851_MPRIP_chr17_16979024_ENST00000444976_length(transcript)=3520nt_BP=479nt
ATTGGCATTGATCTCACAGTCTGGTGAGGACTTCTTTACTGATAATGTCAAGTTCAGGTTATCCTCCCAACCAAGGAGCATTCAGCACAG
AACAAAGTCGTTATCCTCCTCACTCTGTCCAGTATACATTTCCCAACACCCGCCACCAGCAGGAGTTCGCAGTCCCTGATTATCGTTCCT
CTCATCTTGAAGTGAGTCAGGCATCACAGCTTTTGCAGCAACAGCAGCAGCAACAGCTTCGAAGGCGACCTTCCTTGCTTTCAGAATTTC
ACCCAGGTTCTGACAGGCCTCAAGAAAGGAGAACTAGTTATGAACCGTTTCATCCAGGCCCATCCCCAGTGGATCATGATTCACTGGAAT
CGAAGCGACCACGTCTGGAACAGGTTTCTGATTCTCATTTTCAGCGTGTCAGTGCTGCGGTTTTGCCTTTAGTGCACCCGCTGCCAGAAG
GGCTGAGGGCTTCTGCAGATGCTAAGAAGGCAAAACCCATTTATGGCGGTTGGCTGCTCCTGGCTCCAGATGGGACCGACTTTGACAACC
CAGTGCACCGGTCTCGGAAATGGCAGCGACGGTTCTTCATCCTTTACGAGCACGGCCTCTTGCGCTACGCCCTGGATGAGATGCCCACGA
CCCTTCCTCAGGGCACCATCAACATGAACCAGTGCACAGATGTGGTGGATGGGGAGGGCCGCACGGGCCAGAAGTTCTCCCTGTGTATTC
TGACGCCTGAGAAGGAGCATTTCATCCGGGCGGAGACCAAGGAGATCGTCAGTGGGTGGCTGGAGATGCTCATGGTCTATCCCCGGACCA
ACAAGCAGAATCAGAAGAAGAAACGGAAAGTGGAGCCCCCCACACCACAGGAGCCTGGGCCTGCCAAGGTGGCTGTTACCAGCAGCAGCA
GCAGCAGCAGCAGCAGCAGCAGCATCCCCAGTGCTGAGAAAGTCCCCACCACCAAGTCCACACTCTGGCAGGAAGAAATGAGGACCAAGG
ACCAGCCAGATGGCAGCAGCCTGAGTCCAGCTCAGAGTCCCAGCCAGAGCCAGCCTCCTGCTGCCAGCTCCCTGCGGGAACCTGGGCTAG
AGAGCAAAGAAGAGGAGAGCGCCATGAGTAGCGACCGCATGGACTGTGGCCGCAAAGTCCGGGTGGAGAGCGGCTACTTCTCTCTGGAGA
AGACCAAACAGGACTTGAAGGCTGAAGAACAGCAGCTGCCCCCGCCGCTCTCCCCTCCCAGCCCCAGCACCCCCAACCACAGGAGGTCCC
AGGTGATTGAAAAGTTTGAGGCCTTGGACATTGAGAAGGCAGAGCACATGGAGACCAATGCAGTGGGGCCCTCACCATCCAGCGACACAC
GCCAGGGCCGCAGCGAGAAGAGGGCGTTCCCTAGGAAGCGGCCCGACCTGCTGAATTTCAAGAAAGGCTGGCTGACTAAGCAGTATGAGG
ACGGCCAGTGGAAGAAACACTGGTTTGTCCTCGCCGATCAAAGCCTGAGATACTACAGGGATTCAGTGGCTGAGGAGGCAGCCGACTTGG
ATGGAGAAATTGACTTGTCCGCATGTTACGATGTCACAGAGTATCCAGTTCAGAGAAACTATGGCTTCCAGATACATACAAAGGAGGGCG
AGTTTACCCTGTCGGCCATGACATCTGGGATTCGGCGGAACTGGATCCAGACCATCATGAAGCACGTGCACCCGACCACTGCCCCGGATG
TGACCAGCTCGTTGCCAGAGGAAAAAAACAAGAGCAGCTGCTCTTTTGAGACCTGCCCGAGGCCTACTGAGAAGCAAGAGGCAGAGCTGG
GGGAGCCGGACCCTGAGCAGAAGAGGAGCCGCGCACGGGAGCGGAGGCGAGAGGGCCGCTCCAAGACCTTTGACTGGGCTGAGTTCCGTC
CCATCCAGCAGGCCCTGGCTCAGGAGCGGGTGGGCGGCGTGGGGCCTGCTGACACCCACGAGCCCCTGCGCCCTGAGGCGGAGCCTGGGG
AGCTGGAGCGGGAGCGTGCACGGAGGCGGGAGGAGCGCCGCAAGCGCTTCGGGATGCTCGACGCCACAGACGGGCCAGGCACTGAGGATG
CAGCCCTGCGCATGGAGGTGGACCGGAGCCCAGGGCTGCCTATGAGCGACCTCAAAACGCATAACGTCCACGTGGAGATTGAGCAGCGGT
GGCATCAGGTGGAGACCACACCTCTCCGGGAAGAGAAGCAGGTGCCCATCGCCCCCGTCCACCTGTCTTCTGAAGATGGGGGTGACCGGC
TCTCCACACACGAGCTGACCTCTCTGCTCGAGAAGGAGCTGGAGCAGAGCCAGAAGGAGGCCTCAGACCTTCTGGAGCAGAACCGGCTCC
TGCAGGACCAGCTGAGGGTGGCCCTGGGCCGGGAGCAGAGCGCCCGTGAGGGCTACGTGCTGCAGGCCACGTGCGAGCGAGGGTTTGCAG
CAATGGAAGAAACGCACCAGAAGAAGATTGAAGATCTCCAGAGGCAGCACCAGCGGGAGCTAGAGAAACTTCGAGAAGAGAAAGACCGCC
TCCTAGCCGAGGAGACAGCGGCCACCATCTCAGCCATCGAAGCCATGAAGAACGCCCACCGGGAGGAAATGGAGCGGGAGCTGGAGAAGA
GCCAGCGGTCCCAGATCAGCAGCGTCAACTCGGATGTTGAGGCCCTGCGGCGCCAGTACCTGGAGGAGCTGCAGTCGGTGCAGCGGGAAC
TGGAGGTCCTCTCGGAGCAGTACTCGCAGAAGTGCCTGGAGAATGCCCATCTGGCCCAGGCGCTGGAGGCCGAGCGGCAGGCCCTGCGGC
AGTGCCAGCGTGAGAACCAGGAGCTCAATGCCCACAACCAGGAGCTGAACAACCGCCTGGCTGCAGAGATCACACGGTTGCGGACGCTGC
TGACTGGGGACGGCGGTGGGGAGGCCACTGGGTCACCCCTTGCACAGGGCAAGGATGCCTATGAACTAGAGGTCTTATTGCGGGTAAAGG
AATCGGAAATACAGTACCTGAAACAGGAGATTAGCTCCCTCAAGGATGAGCTGCAGACGGCACTGCGGGACAAGAAGTACGCAAGTGACA
AGTACAAAGACATCTACACAGAGCTCAGCATCGCGAAGGCTAAGGCTGACTGTGACATCAGCAGGTTGAAGGAGCAGCTCAAGGCTGCAA
CGGAAGCACTGGGGGAGAAGTCCCCTGACAGTGCCACGGTGTCCGGATATGATATAATGAAATCTAAAAGCAACCCTGACTTCTTGAAGA
AAGACAGATCCTGTGTCACCCGGCAACTCAGAAACATCAGGTCCAAGAGTCTGAAGGAAGGCCTGACGGTGCAAGAACGGTTGAAGCTCT
TTGAATCCAGGGACTTGAAGAAAGACTAGGTGTGTCCCATCCAAGTTGAGCACGCGCCTTCCCCAGCTTGCAGCAGCACACCCCAAGCGC
TGCTTTTCACCTGTACCTTTGTTTTATTATTATTATTATTATTGCTGTTGTTGTCATCGTTAACTGTGGGCATGGAATGCGTGAGGCTGG

>57839_57839_4_NCOR1-MPRIP_NCOR1_chr17_16075117_ENST00000395851_MPRIP_chr17_16979024_ENST00000444976_length(amino acids)=1112AA_BP=153
MVRTSLLIMSSSGYPPNQGAFSTEQSRYPPHSVQYTFPNTRHQQEFAVPDYRSSHLEVSQASQLLQQQQQQQLRRRPSLLSEFHPGSDRP
QERRTSYEPFHPGPSPVDHDSLESKRPRLEQVSDSHFQRVSAAVLPLVHPLPEGLRASADAKKAKPIYGGWLLLAPDGTDFDNPVHRSRK
WQRRFFILYEHGLLRYALDEMPTTLPQGTINMNQCTDVVDGEGRTGQKFSLCILTPEKEHFIRAETKEIVSGWLEMLMVYPRTNKQNQKK
KRKVEPPTPQEPGPAKVAVTSSSSSSSSSSSIPSAEKVPTTKSTLWQEEMRTKDQPDGSSLSPAQSPSQSQPPAASSLREPGLESKEEES
AMSSDRMDCGRKVRVESGYFSLEKTKQDLKAEEQQLPPPLSPPSPSTPNHRRSQVIEKFEALDIEKAEHMETNAVGPSPSSDTRQGRSEK
RAFPRKRPDLLNFKKGWLTKQYEDGQWKKHWFVLADQSLRYYRDSVAEEAADLDGEIDLSACYDVTEYPVQRNYGFQIHTKEGEFTLSAM
TSGIRRNWIQTIMKHVHPTTAPDVTSSLPEEKNKSSCSFETCPRPTEKQEAELGEPDPEQKRSRARERRREGRSKTFDWAEFRPIQQALA
QERVGGVGPADTHEPLRPEAEPGELERERARRREERRKRFGMLDATDGPGTEDAALRMEVDRSPGLPMSDLKTHNVHVEIEQRWHQVETT
PLREEKQVPIAPVHLSSEDGGDRLSTHELTSLLEKELEQSQKEASDLLEQNRLLQDQLRVALGREQSAREGYVLQATCERGFAAMEETHQ
KKIEDLQRQHQRELEKLREEKDRLLAEETAATISAIEAMKNAHREEMERELEKSQRSQISSVNSDVEALRRQYLEELQSVQRELEVLSEQ
YSQKCLENAHLAQALEAERQALRQCQRENQELNAHNQELNNRLAAEITRLRTLLTGDGGGEATGSPLAQGKDAYELEVLLRVKESEIQYL
KQEISSLKDELQTALRDKKYASDKYKDIYTELSIAKAKADCDISRLKEQLKAATEALGEKSPDSATVSGYDIMKSKSNPDFLKKDRSCVT

--------------------------------------------------------------

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Fusion Gene PPI Analysis for NCOR1-MPRIP


check button Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in

ChiPPI page.


check button Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160)
HgeneHgene's interactorsTgeneTgene's interactors


check button - Retained PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenStill interaction with
TgeneMPRIPchr17:16075117chr17:16979024ENST00000341712024824_87941.01231.0PPP1R12A
TgeneMPRIPchr17:16075117chr17:16979024ENST00000395804023824_87941.01026.0PPP1R12A
TgeneMPRIPchr17:16075117chr17:16979024ENST00000395811023824_87941.01039.0PPP1R12A
TgeneMPRIPchr17:16075117chr17:16979024ENST00000444976022824_87941.01001.0PPP1R12A
TgeneMPRIPchr17:16075117chr17:16979024ENST00000341712024546_82441.01231.0RHOA
TgeneMPRIPchr17:16075117chr17:16979024ENST00000395804023546_82441.01026.0RHOA
TgeneMPRIPchr17:16075117chr17:16979024ENST00000395811023546_82441.01039.0RHOA
TgeneMPRIPchr17:16075117chr17:16979024ENST00000444976022546_82441.01001.0RHOA


check button - Lost PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with
HgeneNCOR1chr17:16075117chr17:16979024ENST00000268712-4461501_2440145.02441.0C1D
HgeneNCOR1chr17:16075117chr17:16979024ENST00000395848-1191501_24400915.0C1D
HgeneNCOR1chr17:16075117chr17:16979024ENST00000395851-3451501_2440145.02338.0C1D
HgeneNCOR1chr17:16075117chr17:16979024ENST00000268712-446988_1816145.02441.0ETO
HgeneNCOR1chr17:16075117chr17:16979024ENST00000395848-119988_18160915.0ETO
HgeneNCOR1chr17:16075117chr17:16979024ENST00000395851-345988_1816145.02338.0ETO
HgeneNCOR1chr17:16075117chr17:16979024ENST00000268712-446254_312145.02441.0SIN3A/B
HgeneNCOR1chr17:16075117chr17:16979024ENST00000395848-119254_3120915.0SIN3A/B
HgeneNCOR1chr17:16075117chr17:16979024ENST00000395851-345254_312145.02338.0SIN3A/B
HgeneNCOR1chr17:16075117chr17:16979024ENST00000268712-4461_373145.02441.0ZBTB33 and HEXIM1
HgeneNCOR1chr17:16075117chr17:16979024ENST00000395848-1191_3730915.0ZBTB33 and HEXIM1
HgeneNCOR1chr17:16075117chr17:16979024ENST00000395851-3451_373145.02338.0ZBTB33 and HEXIM1
TgeneMPRIPchr17:16075117chr17:16979024ENST000003417120242_38341.01231.0F-actin
TgeneMPRIPchr17:16075117chr17:16979024ENST000003958040232_38341.01026.0F-actin
TgeneMPRIPchr17:16075117chr17:16979024ENST000003958110232_38341.01039.0F-actin
TgeneMPRIPchr17:16075117chr17:16979024ENST000004449760222_38341.01001.0F-actin


check button - Retained PPIs, but lost function due to frame-shift fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


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Related Drugs for NCOR1-MPRIP


check button Drugs targeting genes involved in this fusion gene.
(DrugBank Version 5.1.8 2021-05-08)
PartnerGeneUniProtAccDrugBank IDDrug nameDrug activityDrug typeDrug status

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Related Diseases for NCOR1-MPRIP


check button Diseases associated with fusion partners.
(DisGeNet 4.0)
PartnerGeneDisease IDDisease name# pubmedsSource