|
||||||
|
 | Fusion Gene Summary |
| Fusion Gene ORF analysis |
| Fusion Genomic Features |
| Fusion Protein Features |
| Fusion Gene Sequence |
| Fusion Gene PPI analysis |
| Related Drugs |
| Related Diseases |
Fusion gene:NEDD4L-ALPK2 (FusionGDB2 ID:58409) |
Fusion Gene Summary for NEDD4L-ALPK2 |
 Fusion gene summary |
| Fusion gene information | Fusion gene name: NEDD4L-ALPK2 | Fusion gene ID: 58409 | Hgene | Tgene | Gene symbol | NEDD4L | ALPK2 | Gene ID | 23327 | 115701 |
| Gene name | NEDD4 like E3 ubiquitin protein ligase | alpha kinase 2 | |
| Synonyms | NEDD4-2|NEDD4.2|PVNH7|RSP5|hNEDD4-2 | HAK | |
| Cytomap | 18q21.31 | 18q21.31-q21.32 | |
| Type of gene | protein-coding | protein-coding | |
| Description | E3 ubiquitin-protein ligase NEDD4-likeHECT-type E3 ubiquitin transferase NED4Lneural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligaseubiquitin-protein ligase Rsp5 | alpha-protein kinase 2heart alpha-kinaseheart alpha-protein kinase | |
| Modification date | 20200329 | 20200313 | |
| UniProtAcc | Q96PU5 | Q86TB3 | |
| Ensembl transtripts involved in fusion gene | ENST00000256830, ENST00000256832, ENST00000356462, ENST00000357895, ENST00000382850, ENST00000400345, ENST00000431212, ENST00000435432, ENST00000456173, ENST00000456986, ENST00000586263, ENST00000589054, ENST00000588516, | ENST00000587399, ENST00000361673, | |
| Fusion gene scores | * DoF score | 28 X 18 X 11=5544 | 3 X 4 X 2=24 |
| # samples | 35 | 4 | |
| ** MAII score | log2(35/5544*10)=-3.98550043030488 possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs). DoF>8 and MAII<0 | log2(4/24*10)=0.736965594166206 effective Gene in Pan-Cancer Fusion Genes (eGinPCFGs). DoF>8 and MAII>0 | |
| Context | PubMed: NEDD4L [Title/Abstract] AND ALPK2 [Title/Abstract] AND fusion [Title/Abstract] | ||
| Most frequent breakpoint | NEDD4L(55711940)-ALPK2(56196470), # samples:5 ALPK2(56169514)-NEDD4L(55987973), # samples:1 | ||
| Anticipated loss of major functional domain due to fusion event. | NEDD4L-ALPK2 seems lost the major protein functional domain in Hgene partner, which is a essential gene due to the frame-shifted ORF. NEDD4L-ALPK2 seems lost the major protein functional domain in Hgene partner, which is a tumor suppressor due to the frame-shifted ORF. NEDD4L-ALPK2 seems lost the major protein functional domain in Tgene partner, which is a kinase due to the frame-shifted ORF. | ||
| * DoF score (Degree of Frequency) = # partners X # break points X # cancer types ** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10) |
| Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez |
| Partner | Gene | GO ID | GO term | PubMed ID |
| Hgene | NEDD4L | GO:0003254 | regulation of membrane depolarization | 15217910 |
| Hgene | NEDD4L | GO:0006511 | ubiquitin-dependent protein catabolic process | 21463633 |
| Hgene | NEDD4L | GO:0010038 | response to metal ion | 11244092 |
| Hgene | NEDD4L | GO:0016567 | protein ubiquitination | 15217910|25631046 |
| Hgene | NEDD4L | GO:0034765 | regulation of ion transmembrane transport | 17289006 |
| Hgene | NEDD4L | GO:0042391 | regulation of membrane potential | 17289006 |
| Hgene | NEDD4L | GO:0043161 | proteasome-mediated ubiquitin-dependent protein catabolic process | 21463633 |
| Hgene | NEDD4L | GO:0060306 | regulation of membrane repolarization | 21463633 |
| Hgene | NEDD4L | GO:0070936 | protein K48-linked ubiquitination | 21463633 |
| Hgene | NEDD4L | GO:1901016 | regulation of potassium ion transmembrane transporter activity | 17289006 |
| Hgene | NEDD4L | GO:1901017 | negative regulation of potassium ion transmembrane transporter activity | 21463633 |
| Hgene | NEDD4L | GO:1901380 | negative regulation of potassium ion transmembrane transport | 21463633 |
| Hgene | NEDD4L | GO:1902306 | negative regulation of sodium ion transmembrane transport | 15217910 |
| Hgene | NEDD4L | GO:1903861 | positive regulation of dendrite extension | 23999003 |
| Hgene | NEDD4L | GO:2000009 | negative regulation of protein localization to cell surface | 21463633 |
| Hgene | NEDD4L | GO:2000650 | negative regulation of sodium ion transmembrane transporter activity | 15217910 |
| Fusion gene breakpoints across NEDD4L (5'-gene) * Click on the image to open the UCSC genome browser with custom track showing this image in a new window. |
 |
| Fusion gene breakpoints across ALPK2 (3'-gene) * Click on the image to open the UCSC genome browser with custom track showing this image in a new window. |
 |
| Fusion gene information from two resources (ChiTars 5.0 and ChimerDB 4.0) * All genome coordinats were lifted-over on hg19. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| Source | Disease | Sample | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| ChimerDB4 | STAD | TCGA-VQ-A8PD-01A | NEDD4L | chr18 | 55711940 | - | ALPK2 | chr18 | 56196470 | - |
| ChimerDB4 | STAD | TCGA-VQ-A8PD-01A | NEDD4L | chr18 | 55711940 | + | ALPK2 | chr18 | 56196470 | - |
| ChimerDB4 | STAD | TCGA-VQ-A8PD | NEDD4L | chr18 | 55711940 | + | ALPK2 | chr18 | 56196470 | - |
| ChimerDB4 | STAD | TCGA-VQ-A8PX-01A | NEDD4L | chr18 | 56033460 | + | ALPK2 | chr18 | 56191294 | - |
| ChimerDB4 | UCEC | TCGA-B5-A11L | NEDD4L | chr18 | 55711940 | + | ALPK2 | chr18 | 56196470 | - |
Top |
Fusion Gene ORF analysis for NEDD4L-ALPK2 |
| Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| ORF | Henst | Tenst | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| 5CDS-intron | ENST00000256830 | ENST00000587399 | NEDD4L | chr18 | 55711940 | + | ALPK2 | chr18 | 56196470 | - |
| 5CDS-intron | ENST00000256830 | ENST00000587399 | NEDD4L | chr18 | 56033460 | + | ALPK2 | chr18 | 56191294 | - |
| 5CDS-intron | ENST00000256832 | ENST00000587399 | NEDD4L | chr18 | 56033460 | + | ALPK2 | chr18 | 56191294 | - |
| 5CDS-intron | ENST00000356462 | ENST00000587399 | NEDD4L | chr18 | 55711940 | + | ALPK2 | chr18 | 56196470 | - |
| 5CDS-intron | ENST00000356462 | ENST00000587399 | NEDD4L | chr18 | 56033460 | + | ALPK2 | chr18 | 56191294 | - |
| 5CDS-intron | ENST00000357895 | ENST00000587399 | NEDD4L | chr18 | 56033460 | + | ALPK2 | chr18 | 56191294 | - |
| 5CDS-intron | ENST00000382850 | ENST00000587399 | NEDD4L | chr18 | 55711940 | + | ALPK2 | chr18 | 56196470 | - |
| 5CDS-intron | ENST00000382850 | ENST00000587399 | NEDD4L | chr18 | 56033460 | + | ALPK2 | chr18 | 56191294 | - |
| 5CDS-intron | ENST00000400345 | ENST00000587399 | NEDD4L | chr18 | 55711940 | + | ALPK2 | chr18 | 56196470 | - |
| 5CDS-intron | ENST00000400345 | ENST00000587399 | NEDD4L | chr18 | 56033460 | + | ALPK2 | chr18 | 56191294 | - |
| 5CDS-intron | ENST00000431212 | ENST00000587399 | NEDD4L | chr18 | 56033460 | + | ALPK2 | chr18 | 56191294 | - |
| 5CDS-intron | ENST00000435432 | ENST00000587399 | NEDD4L | chr18 | 56033460 | + | ALPK2 | chr18 | 56191294 | - |
| 5CDS-intron | ENST00000456173 | ENST00000587399 | NEDD4L | chr18 | 56033460 | + | ALPK2 | chr18 | 56191294 | - |
| 5CDS-intron | ENST00000456986 | ENST00000587399 | NEDD4L | chr18 | 56033460 | + | ALPK2 | chr18 | 56191294 | - |
| 5CDS-intron | ENST00000586263 | ENST00000587399 | NEDD4L | chr18 | 56033460 | + | ALPK2 | chr18 | 56191294 | - |
| 5CDS-intron | ENST00000589054 | ENST00000587399 | NEDD4L | chr18 | 55711940 | + | ALPK2 | chr18 | 56196470 | - |
| 5UTR-3CDS | ENST00000256832 | ENST00000361673 | NEDD4L | chr18 | 55711940 | + | ALPK2 | chr18 | 56196470 | - |
| 5UTR-intron | ENST00000256832 | ENST00000587399 | NEDD4L | chr18 | 55711940 | + | ALPK2 | chr18 | 56196470 | - |
| Frame-shift | ENST00000256830 | ENST00000361673 | NEDD4L | chr18 | 55711940 | + | ALPK2 | chr18 | 56196470 | - |
| Frame-shift | ENST00000356462 | ENST00000361673 | NEDD4L | chr18 | 55711940 | + | ALPK2 | chr18 | 56196470 | - |
| Frame-shift | ENST00000382850 | ENST00000361673 | NEDD4L | chr18 | 55711940 | + | ALPK2 | chr18 | 56196470 | - |
| Frame-shift | ENST00000400345 | ENST00000361673 | NEDD4L | chr18 | 55711940 | + | ALPK2 | chr18 | 56196470 | - |
| Frame-shift | ENST00000589054 | ENST00000361673 | NEDD4L | chr18 | 55711940 | + | ALPK2 | chr18 | 56196470 | - |
| In-frame | ENST00000256830 | ENST00000361673 | NEDD4L | chr18 | 56033460 | + | ALPK2 | chr18 | 56191294 | - |
| In-frame | ENST00000256832 | ENST00000361673 | NEDD4L | chr18 | 56033460 | + | ALPK2 | chr18 | 56191294 | - |
| In-frame | ENST00000356462 | ENST00000361673 | NEDD4L | chr18 | 56033460 | + | ALPK2 | chr18 | 56191294 | - |
| In-frame | ENST00000357895 | ENST00000361673 | NEDD4L | chr18 | 56033460 | + | ALPK2 | chr18 | 56191294 | - |
| In-frame | ENST00000382850 | ENST00000361673 | NEDD4L | chr18 | 56033460 | + | ALPK2 | chr18 | 56191294 | - |
| In-frame | ENST00000400345 | ENST00000361673 | NEDD4L | chr18 | 56033460 | + | ALPK2 | chr18 | 56191294 | - |
| In-frame | ENST00000431212 | ENST00000361673 | NEDD4L | chr18 | 56033460 | + | ALPK2 | chr18 | 56191294 | - |
| In-frame | ENST00000435432 | ENST00000361673 | NEDD4L | chr18 | 56033460 | + | ALPK2 | chr18 | 56191294 | - |
| In-frame | ENST00000456173 | ENST00000361673 | NEDD4L | chr18 | 56033460 | + | ALPK2 | chr18 | 56191294 | - |
| In-frame | ENST00000456986 | ENST00000361673 | NEDD4L | chr18 | 56033460 | + | ALPK2 | chr18 | 56191294 | - |
| In-frame | ENST00000586263 | ENST00000361673 | NEDD4L | chr18 | 56033460 | + | ALPK2 | chr18 | 56191294 | - |
| intron-3CDS | ENST00000357895 | ENST00000361673 | NEDD4L | chr18 | 55711940 | + | ALPK2 | chr18 | 56196470 | - |
| intron-3CDS | ENST00000431212 | ENST00000361673 | NEDD4L | chr18 | 55711940 | + | ALPK2 | chr18 | 56196470 | - |
| intron-3CDS | ENST00000435432 | ENST00000361673 | NEDD4L | chr18 | 55711940 | + | ALPK2 | chr18 | 56196470 | - |
| intron-3CDS | ENST00000456173 | ENST00000361673 | NEDD4L | chr18 | 55711940 | + | ALPK2 | chr18 | 56196470 | - |
| intron-3CDS | ENST00000456986 | ENST00000361673 | NEDD4L | chr18 | 55711940 | + | ALPK2 | chr18 | 56196470 | - |
| intron-3CDS | ENST00000586263 | ENST00000361673 | NEDD4L | chr18 | 55711940 | + | ALPK2 | chr18 | 56196470 | - |
| intron-3CDS | ENST00000588516 | ENST00000361673 | NEDD4L | chr18 | 55711940 | + | ALPK2 | chr18 | 56196470 | - |
| intron-3CDS | ENST00000588516 | ENST00000361673 | NEDD4L | chr18 | 56033460 | + | ALPK2 | chr18 | 56191294 | - |
| intron-3CDS | ENST00000589054 | ENST00000361673 | NEDD4L | chr18 | 56033460 | + | ALPK2 | chr18 | 56191294 | - |
| intron-intron | ENST00000357895 | ENST00000587399 | NEDD4L | chr18 | 55711940 | + | ALPK2 | chr18 | 56196470 | - |
| intron-intron | ENST00000431212 | ENST00000587399 | NEDD4L | chr18 | 55711940 | + | ALPK2 | chr18 | 56196470 | - |
| intron-intron | ENST00000435432 | ENST00000587399 | NEDD4L | chr18 | 55711940 | + | ALPK2 | chr18 | 56196470 | - |
| intron-intron | ENST00000456173 | ENST00000587399 | NEDD4L | chr18 | 55711940 | + | ALPK2 | chr18 | 56196470 | - |
| intron-intron | ENST00000456986 | ENST00000587399 | NEDD4L | chr18 | 55711940 | + | ALPK2 | chr18 | 56196470 | - |
| intron-intron | ENST00000586263 | ENST00000587399 | NEDD4L | chr18 | 55711940 | + | ALPK2 | chr18 | 56196470 | - |
| intron-intron | ENST00000588516 | ENST00000587399 | NEDD4L | chr18 | 55711940 | + | ALPK2 | chr18 | 56196470 | - |
| intron-intron | ENST00000588516 | ENST00000587399 | NEDD4L | chr18 | 56033460 | + | ALPK2 | chr18 | 56191294 | - |
| intron-intron | ENST00000589054 | ENST00000587399 | NEDD4L | chr18 | 56033460 | + | ALPK2 | chr18 | 56191294 | - |
| ORFfinder result based on the fusion transcript sequence of in-frame fusion genes. |
| Henst | Tenst | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand | Seq length (transcript) | BP loci (transcript) | Predicted start (transcript) | Predicted stop (transcript) | Seq length (amino acids) |
| ENST00000356462 | NEDD4L | chr18 | 56033460 | + | ENST00000361673 | ALPK2 | chr18 | 56191294 | - | 3753 | 2165 | 210 | 3176 | 988 |
| ENST00000400345 | NEDD4L | chr18 | 56033460 | + | ENST00000361673 | ALPK2 | chr18 | 56191294 | - | 3934 | 2346 | 199 | 3357 | 1052 |
| ENST00000256832 | NEDD4L | chr18 | 56033460 | + | ENST00000361673 | ALPK2 | chr18 | 56191294 | - | 3868 | 2280 | 190 | 3291 | 1033 |
| ENST00000382850 | NEDD4L | chr18 | 56033460 | + | ENST00000361673 | ALPK2 | chr18 | 56191294 | - | 3704 | 2116 | 29 | 3127 | 1032 |
| ENST00000256830 | NEDD4L | chr18 | 56033460 | + | ENST00000361673 | ALPK2 | chr18 | 56191294 | - | 3339 | 1751 | 0 | 2762 | 920 |
| ENST00000456986 | NEDD4L | chr18 | 56033460 | + | ENST00000361673 | ALPK2 | chr18 | 56191294 | - | 3888 | 2300 | 381 | 3311 | 976 |
| ENST00000435432 | NEDD4L | chr18 | 56033460 | + | ENST00000361673 | ALPK2 | chr18 | 56191294 | - | 3858 | 2270 | 411 | 3281 | 956 |
| ENST00000357895 | NEDD4L | chr18 | 56033460 | + | ENST00000361673 | ALPK2 | chr18 | 56191294 | - | 3830 | 2242 | 203 | 3253 | 1016 |
| ENST00000586263 | NEDD4L | chr18 | 56033460 | + | ENST00000361673 | ALPK2 | chr18 | 56191294 | - | 3766 | 2178 | 199 | 3189 | 996 |
| ENST00000456173 | NEDD4L | chr18 | 56033460 | + | ENST00000361673 | ALPK2 | chr18 | 56191294 | - | 3813 | 2225 | 114 | 3236 | 1040 |
| ENST00000431212 | NEDD4L | chr18 | 56033460 | + | ENST00000361673 | ALPK2 | chr18 | 56191294 | - | 3752 | 2164 | 191 | 3175 | 994 |
| DeepORF prediction of the coding potential based on the fusion transcript sequence of in-frame fusion genes. DeepORF is a coding potential classifier based on convolutional neural network by comparing the real Ribo-seq data. If the no-coding score < 0.5 and coding score > 0.5, then the in-frame fusion transcript is predicted as being likely translated. |
| Henst | Tenst | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand | No-coding score | Coding score |
| ENST00000356462 | ENST00000361673 | NEDD4L | chr18 | 56033460 | + | ALPK2 | chr18 | 56191294 | - | 0.000693442 | 0.99930656 |
| ENST00000400345 | ENST00000361673 | NEDD4L | chr18 | 56033460 | + | ALPK2 | chr18 | 56191294 | - | 0.000657147 | 0.99934286 |
| ENST00000256832 | ENST00000361673 | NEDD4L | chr18 | 56033460 | + | ALPK2 | chr18 | 56191294 | - | 0.001050667 | 0.99894935 |
| ENST00000382850 | ENST00000361673 | NEDD4L | chr18 | 56033460 | + | ALPK2 | chr18 | 56191294 | - | 0.001015315 | 0.99898463 |
| ENST00000256830 | ENST00000361673 | NEDD4L | chr18 | 56033460 | + | ALPK2 | chr18 | 56191294 | - | 0.000649414 | 0.9993506 |
| ENST00000456986 | ENST00000361673 | NEDD4L | chr18 | 56033460 | + | ALPK2 | chr18 | 56191294 | - | 0.000612778 | 0.99938715 |
| ENST00000435432 | ENST00000361673 | NEDD4L | chr18 | 56033460 | + | ALPK2 | chr18 | 56191294 | - | 0.000616723 | 0.9993832 |
| ENST00000357895 | ENST00000361673 | NEDD4L | chr18 | 56033460 | + | ALPK2 | chr18 | 56191294 | - | 0.000535469 | 0.9994646 |
| ENST00000586263 | ENST00000361673 | NEDD4L | chr18 | 56033460 | + | ALPK2 | chr18 | 56191294 | - | 0.000478667 | 0.9995214 |
| ENST00000456173 | ENST00000361673 | NEDD4L | chr18 | 56033460 | + | ALPK2 | chr18 | 56191294 | - | 0.0008379 | 0.9991621 |
| ENST00000431212 | ENST00000361673 | NEDD4L | chr18 | 56033460 | + | ALPK2 | chr18 | 56191294 | - | 0.000701727 | 0.9992982 |
Top |
Fusion Genomic Features for NEDD4L-ALPK2 |
| FusionAI prediction of the potential fusion gene breakpoint based on the pre-mature RNA sequence context (+/- 5kb of individual partner genes, total 20kb length sequence). FusionAI is a fusion gene breakpoint classifier based on convolutional neural network by comparing the fusion positive and negative sequence context of ~ 20K fusion gene data. From here, we can have the relative potentency of the 20K genomic sequence how individual sequnce will be likely used as the gene fusion breakpoints. |
| Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand | 1-p | p (fusion gene breakpoint) |
| Distribution of 44 human genomic features loci across 20kb length fusion breakpoint regions. We integrated a total of 44 different types of human genomic feature loci information across five big categories including virus integration sites, repeats, structural variants, chromatin states, and gene expression regulation. More details are in help page. |
 |
| Distribution of 44 human genomic features loci across 20kb length fusion breakpoint regions that are ovelapped with the top 1% feature importance score regions. More details are in help page. |
Top |
Fusion Protein Features for NEDD4L-ALPK2 |
| Four levels of functional features of fusion genes Go to FGviewer search page for the most frequent breakpoint (https://ccsmweb.uth.edu/FGviewer/chr18:55711940/chr18:56196470) - FGviewer provides the online visualization of the retention search of the protein functional features across DNA, RNA, protein, and pathological levels. - How to search 1. Put your fusion gene symbol. 2. Press the tab key until there will be shown the breakpoint information filled. 4. Go down and press 'Search' tab twice. 4. Go down to have the hyperlink of the search result. 5. Click the hyperlink. 6. See the FGviewer result for your fusion gene. |
 |
| Main function of each fusion partner protein. (from UniProt) |
| Hgene | Tgene |
| NEDD4L | ALPK2 |
| FUNCTION: E3 ubiquitin-protein ligase which accepts ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfers the ubiquitin to targeted substrates. Inhibits TGF-beta signaling by triggering SMAD2 and TGFBR1 ubiquitination and proteasome-dependent degradation. Promotes ubiquitination and internalization of various plasma membrane channels such as ENaC, SCN2A/Nav1.2, SCN3A/Nav1.3, SCN5A/Nav1.5, SCN9A/Nav1.7, SCN10A/Nav1.8, KCNA3/Kv1.3, KCNH2, EAAT1, KCNQ2/Kv7.2, KCNQ3/Kv7.3 or CLC5 (PubMed:26363003, PubMed:27445338). Promotes ubiquitination and degradation of SGK1 and TNK2. Ubiquitinates BRAT1 and this ubiquitination is enhanced in the presence of NDFIP1 (PubMed:25631046). Plays a role in dendrite formation by melanocytes (PubMed:23999003). Involved in the regulation of TOR signaling (PubMed:27694961). Ubiquitinates and regulates protein levels of NTRK1 once this one is activated by NGF (PubMed:27445338). {ECO:0000250|UniProtKB:Q8CFI0, ECO:0000269|PubMed:12911626, ECO:0000269|PubMed:15040001, ECO:0000269|PubMed:15217910, ECO:0000269|PubMed:15489223, ECO:0000269|PubMed:15496141, ECO:0000269|PubMed:15576372, ECO:0000269|PubMed:19144635, ECO:0000269|PubMed:23999003, ECO:0000269|PubMed:25631046, ECO:0000269|PubMed:26363003, ECO:0000269|PubMed:27445338, ECO:0000269|PubMed:27694961}. | FUNCTION: Protein kinase that recognizes phosphorylation sites in which the surrounding peptides have an alpha-helical conformation (PubMed:10021370). Regulates cardiac development and cardiomyocyte differentiation by negatively regulating Wnt/beta-catenin signaling (PubMed:29888752). {ECO:0000269|PubMed:29888752, ECO:0000303|PubMed:10021370}. |
| Retention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at * Minus value of BPloci means that the break pointn is located before the CDS. |
| - In-frame and retained protein feature among the 13 regional features. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Protein feature | Protein feature note |
| Hgene | NEDD4L | chr18:56033460 | chr18:56191294 | ENST00000256830 | + | 18 | 28 | 193_226 | 583 | 872.0 | Domain | WW 1 |
| Hgene | NEDD4L | chr18:56033460 | chr18:56191294 | ENST00000256830 | + | 18 | 28 | 385_418 | 583 | 872.0 | Domain | WW 2 |
| Hgene | NEDD4L | chr18:56033460 | chr18:56191294 | ENST00000256830 | + | 18 | 28 | 497_530 | 583 | 872.0 | Domain | WW 3 |
| Hgene | NEDD4L | chr18:56033460 | chr18:56191294 | ENST00000256830 | + | 18 | 28 | 4_126 | 583 | 872.0 | Domain | C2 |
| Hgene | NEDD4L | chr18:56033460 | chr18:56191294 | ENST00000256830 | + | 18 | 28 | 548_581 | 583 | 872.0 | Domain | WW 4 |
| Hgene | NEDD4L | chr18:56033460 | chr18:56191294 | ENST00000356462 | + | 19 | 29 | 193_226 | 623 | 912.0 | Domain | WW 1 |
| Hgene | NEDD4L | chr18:56033460 | chr18:56191294 | ENST00000356462 | + | 19 | 29 | 385_418 | 623 | 912.0 | Domain | WW 2 |
| Hgene | NEDD4L | chr18:56033460 | chr18:56191294 | ENST00000356462 | + | 19 | 29 | 497_530 | 623 | 912.0 | Domain | WW 3 |
| Hgene | NEDD4L | chr18:56033460 | chr18:56191294 | ENST00000356462 | + | 19 | 29 | 4_126 | 623 | 912.0 | Domain | C2 |
| Hgene | NEDD4L | chr18:56033460 | chr18:56191294 | ENST00000356462 | + | 19 | 29 | 548_581 | 623 | 912.0 | Domain | WW 4 |
| Hgene | NEDD4L | chr18:56033460 | chr18:56191294 | ENST00000357895 | + | 21 | 31 | 193_226 | 679 | 968.0 | Domain | WW 1 |
| Hgene | NEDD4L | chr18:56033460 | chr18:56191294 | ENST00000357895 | + | 21 | 31 | 385_418 | 679 | 968.0 | Domain | WW 2 |
| Hgene | NEDD4L | chr18:56033460 | chr18:56191294 | ENST00000357895 | + | 21 | 31 | 497_530 | 679 | 968.0 | Domain | WW 3 |
| Hgene | NEDD4L | chr18:56033460 | chr18:56191294 | ENST00000357895 | + | 21 | 31 | 4_126 | 679 | 968.0 | Domain | C2 |
| Hgene | NEDD4L | chr18:56033460 | chr18:56191294 | ENST00000357895 | + | 21 | 31 | 548_581 | 679 | 968.0 | Domain | WW 4 |
| Hgene | NEDD4L | chr18:56033460 | chr18:56191294 | ENST00000382850 | + | 20 | 30 | 193_226 | 667 | 956.0 | Domain | WW 1 |
| Hgene | NEDD4L | chr18:56033460 | chr18:56191294 | ENST00000382850 | + | 20 | 30 | 385_418 | 667 | 956.0 | Domain | WW 2 |
| Hgene | NEDD4L | chr18:56033460 | chr18:56191294 | ENST00000382850 | + | 20 | 30 | 497_530 | 667 | 956.0 | Domain | WW 3 |
| Hgene | NEDD4L | chr18:56033460 | chr18:56191294 | ENST00000382850 | + | 20 | 30 | 4_126 | 667 | 956.0 | Domain | C2 |
| Hgene | NEDD4L | chr18:56033460 | chr18:56191294 | ENST00000382850 | + | 20 | 30 | 548_581 | 667 | 956.0 | Domain | WW 4 |
| Hgene | NEDD4L | chr18:56033460 | chr18:56191294 | ENST00000400345 | + | 21 | 31 | 193_226 | 687 | 976.0 | Domain | WW 1 |
| Hgene | NEDD4L | chr18:56033460 | chr18:56191294 | ENST00000400345 | + | 21 | 31 | 385_418 | 687 | 976.0 | Domain | WW 2 |
| Hgene | NEDD4L | chr18:56033460 | chr18:56191294 | ENST00000400345 | + | 21 | 31 | 497_530 | 687 | 976.0 | Domain | WW 3 |
| Hgene | NEDD4L | chr18:56033460 | chr18:56191294 | ENST00000400345 | + | 21 | 31 | 4_126 | 687 | 976.0 | Domain | C2 |
| Hgene | NEDD4L | chr18:56033460 | chr18:56191294 | ENST00000400345 | + | 21 | 31 | 548_581 | 687 | 976.0 | Domain | WW 4 |
| Hgene | NEDD4L | chr18:56033460 | chr18:56191294 | ENST00000431212 | + | 20 | 30 | 193_226 | 566 | 855.0 | Domain | WW 1 |
| Hgene | NEDD4L | chr18:56033460 | chr18:56191294 | ENST00000431212 | + | 20 | 30 | 385_418 | 566 | 855.0 | Domain | WW 2 |
| Hgene | NEDD4L | chr18:56033460 | chr18:56191294 | ENST00000431212 | + | 20 | 30 | 497_530 | 566 | 855.0 | Domain | WW 3 |
| Hgene | NEDD4L | chr18:56033460 | chr18:56191294 | ENST00000431212 | + | 20 | 30 | 4_126 | 566 | 855.0 | Domain | C2 |
| Hgene | NEDD4L | chr18:56033460 | chr18:56191294 | ENST00000435432 | + | 21 | 31 | 193_226 | 546 | 835.0 | Domain | WW 1 |
| Hgene | NEDD4L | chr18:56033460 | chr18:56191294 | ENST00000435432 | + | 21 | 31 | 385_418 | 546 | 835.0 | Domain | WW 2 |
| Hgene | NEDD4L | chr18:56033460 | chr18:56191294 | ENST00000435432 | + | 21 | 31 | 497_530 | 546 | 835.0 | Domain | WW 3 |
| Hgene | NEDD4L | chr18:56033460 | chr18:56191294 | ENST00000435432 | + | 21 | 31 | 4_126 | 546 | 835.0 | Domain | C2 |
| Hgene | NEDD4L | chr18:56033460 | chr18:56191294 | ENST00000456173 | + | 19 | 29 | 193_226 | 546 | 835.0 | Domain | WW 1 |
| Hgene | NEDD4L | chr18:56033460 | chr18:56191294 | ENST00000456173 | + | 19 | 29 | 385_418 | 546 | 835.0 | Domain | WW 2 |
| Hgene | NEDD4L | chr18:56033460 | chr18:56191294 | ENST00000456173 | + | 19 | 29 | 497_530 | 546 | 835.0 | Domain | WW 3 |
| Hgene | NEDD4L | chr18:56033460 | chr18:56191294 | ENST00000456173 | + | 19 | 29 | 4_126 | 546 | 835.0 | Domain | C2 |
| Hgene | NEDD4L | chr18:56033460 | chr18:56191294 | ENST00000456986 | + | 21 | 31 | 193_226 | 566 | 855.0 | Domain | WW 1 |
| Hgene | NEDD4L | chr18:56033460 | chr18:56191294 | ENST00000456986 | + | 21 | 31 | 385_418 | 566 | 855.0 | Domain | WW 2 |
| Hgene | NEDD4L | chr18:56033460 | chr18:56191294 | ENST00000456986 | + | 21 | 31 | 497_530 | 566 | 855.0 | Domain | WW 3 |
| Hgene | NEDD4L | chr18:56033460 | chr18:56191294 | ENST00000456986 | + | 21 | 31 | 4_126 | 566 | 855.0 | Domain | C2 |
| Hgene | NEDD4L | chr18:56033460 | chr18:56191294 | ENST00000586263 | + | 20 | 30 | 193_226 | 659 | 948.0 | Domain | WW 1 |
| Hgene | NEDD4L | chr18:56033460 | chr18:56191294 | ENST00000586263 | + | 20 | 30 | 385_418 | 659 | 948.0 | Domain | WW 2 |
| Hgene | NEDD4L | chr18:56033460 | chr18:56191294 | ENST00000586263 | + | 20 | 30 | 497_530 | 659 | 948.0 | Domain | WW 3 |
| Hgene | NEDD4L | chr18:56033460 | chr18:56191294 | ENST00000586263 | + | 20 | 30 | 4_126 | 659 | 948.0 | Domain | C2 |
| Hgene | NEDD4L | chr18:56033460 | chr18:56191294 | ENST00000586263 | + | 20 | 30 | 548_581 | 659 | 948.0 | Domain | WW 4 |
| Tgene | ALPK2 | chr18:56033460 | chr18:56191294 | ENST00000361673 | 5 | 13 | 1901_2133 | 1833 | 2171.0 | Domain | Alpha-type protein kinase |
| - In-frame and not-retained protein feature among the 13 regional features. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Protein feature | Protein feature note |
| Hgene | NEDD4L | chr18:56033460 | chr18:56191294 | ENST00000256830 | + | 18 | 28 | 640_974 | 583 | 872.0 | Domain | HECT |
| Hgene | NEDD4L | chr18:56033460 | chr18:56191294 | ENST00000356462 | + | 19 | 29 | 640_974 | 623 | 912.0 | Domain | HECT |
| Hgene | NEDD4L | chr18:56033460 | chr18:56191294 | ENST00000357895 | + | 21 | 31 | 640_974 | 679 | 968.0 | Domain | HECT |
| Hgene | NEDD4L | chr18:56033460 | chr18:56191294 | ENST00000382850 | + | 20 | 30 | 640_974 | 667 | 956.0 | Domain | HECT |
| Hgene | NEDD4L | chr18:56033460 | chr18:56191294 | ENST00000400345 | + | 21 | 31 | 640_974 | 687 | 976.0 | Domain | HECT |
| Hgene | NEDD4L | chr18:56033460 | chr18:56191294 | ENST00000431212 | + | 20 | 30 | 548_581 | 566 | 855.0 | Domain | WW 4 |
| Hgene | NEDD4L | chr18:56033460 | chr18:56191294 | ENST00000431212 | + | 20 | 30 | 640_974 | 566 | 855.0 | Domain | HECT |
| Hgene | NEDD4L | chr18:56033460 | chr18:56191294 | ENST00000435432 | + | 21 | 31 | 548_581 | 546 | 835.0 | Domain | WW 4 |
| Hgene | NEDD4L | chr18:56033460 | chr18:56191294 | ENST00000435432 | + | 21 | 31 | 640_974 | 546 | 835.0 | Domain | HECT |
| Hgene | NEDD4L | chr18:56033460 | chr18:56191294 | ENST00000456173 | + | 19 | 29 | 548_581 | 546 | 835.0 | Domain | WW 4 |
| Hgene | NEDD4L | chr18:56033460 | chr18:56191294 | ENST00000456173 | + | 19 | 29 | 640_974 | 546 | 835.0 | Domain | HECT |
| Hgene | NEDD4L | chr18:56033460 | chr18:56191294 | ENST00000456986 | + | 21 | 31 | 548_581 | 566 | 855.0 | Domain | WW 4 |
| Hgene | NEDD4L | chr18:56033460 | chr18:56191294 | ENST00000456986 | + | 21 | 31 | 640_974 | 566 | 855.0 | Domain | HECT |
| Hgene | NEDD4L | chr18:56033460 | chr18:56191294 | ENST00000586263 | + | 20 | 30 | 640_974 | 659 | 948.0 | Domain | HECT |
| Tgene | ALPK2 | chr18:56033460 | chr18:56191294 | ENST00000361673 | 5 | 13 | 1644_1649 | 1833 | 2171.0 | Compositional bias | Poly-Ser | |
| Tgene | ALPK2 | chr18:56033460 | chr18:56191294 | ENST00000361673 | 5 | 13 | 10_114 | 1833 | 2171.0 | Domain | Ig-like 1 | |
| Tgene | ALPK2 | chr18:56033460 | chr18:56191294 | ENST00000361673 | 5 | 13 | 1786_1874 | 1833 | 2171.0 | Domain | Ig-like 2 |
Top |
Fusion Gene Sequence for NEDD4L-ALPK2 |
| For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. To have fusion amino acid sequence, we ran ORFfinder and chose the longest ORF among the all predicted ones. |
| >58409_58409_1_NEDD4L-ALPK2_NEDD4L_chr18_56033460_ENST00000256830_ALPK2_chr18_56191294_ENST00000361673_length(transcript)=3339nt_BP=1751nt ATGGCGACCGGGCTCGGGGAGCCGGTCTATGGACTTTCCGAAGACGAGGGAGAGTCCCGTATTCTCAGAGTAAAAGTTGTTTCTGGAATT GATCTCGCCAAAAAGGACATCTTTGGAGCCAGTGATCCGTATGTGAAACTTTCATTGTACGTAGCGGATGAGAATAGAGAACTTGCTTTG GTCCAGACAAAAACAATTAAAAAGACACTGAACCCAAAATGGAATGAAGAATTTTATTTCAGGGTAAACCCATCTAATCACAGACTCCTA TTTGAAGTATTTGACGAAAATAGACTGACACGAGACGACTTCCTGGGCCAGGTGGACGTGCCCCTTAGTCACCTTCCGACAGAAGATCCA ACCATGGAGCGACCCTATACATTTAAGGACTTTCTCCTCAGACCAAGAAGTCATAAGTCTCGAGTTAAGGGATTTTTGCGATTGAAAATG GCCTATATGCCAAAAAATGGAGGTCAAGATGAAGAAAACAGTGACCAGAGGGATGACATGGAGCATGGATGGGAAGTTGTTGACTCAAAT GACTCGGCTTCTCAGCACCAAGAGGAACTTCCTCCTCCTCCTCTGCCTCCCGGGTGGGAAGAAAAAGTGGACAATTTAGGCCGAACTTAC TATGTCAACCACAACAACCGGACCACTCAGTGGCACAGACCAAGCCTGATGGACGTGTCCTCGGAGTCGGACAATAACATCAGACAGATC AACCAGGAGGCAGCACACCGGCGCTTCCGCTCCCGCAGGCACATCAGCGAAGACTTGGAGCCCGAGCCCTCGGAGGGCGGGGATGTCCCC GAGCCTTGGGAGACCATTTCAGAGGAAGTGAATATCGCTGGAGACTCTCTCGGTCTGGCTCTGCCCCCACCACCGGCCTCCCCAGGATCT CGGACCAGCCCTCAGGAGCTGTCAGAGGAACTAAGCAGAAGGCTTCAGATCACTCCAGACTCCAATGGGGAACAGTTCAGCTCTTTGATT CAAAGAGAACCCTCCTCAAGGTTGAGGTCATGCAGTGTCACCGACGCAGTTGCAGAACAGGGCCATCTACCACCGGGTGCCAAGGACTCA CCCGTACGTCGGGCTGTGAAAGACACCCTTTCCAACCCACAGTCCCCACAGCCATCACCTTACAACTCCCCCAAACCACAACACAAAGTC ACACAGAGCTTCTTGCCACCCGGCTGGGAAATGAGGATAGCGCCAAACGGCCGGCCCTTCTTCATTGATCATAACACAAAGACTACAACC TGGGAAGATCCACGTTTGAAATTTCCAGTACATATGCGGTCAAAGACATCTTTAAACCCCAATGACCTTGGCCCCCTTCCTCCTGGCTGG GAAGAAAGAATTCACTTGGATGGCCGAACGTTTTATATTGATCATAATAGCAAAATTACTCAGTGGGAAGACCCAAGACTGCAGAACCCA GCTATTACTGGTCCGGCTGTCCCTTACTCCAGAGAATTTAAGCAGAAATATGACTACTTCAGGAAGAAATTAAAGAAACCTGCTGATATC CCCAATAGGTTTGAAATGAAACTTCACAGAAATAACATATTTGAAGAGTCCTATCGGAGAATTATGTCCGTGAAAAGACCAGATGTCCTA AAAGCTAGACTGTGGATTGAGTTTGAATCAGAGAAAGGTCTTGACTATGGGGGTGTGGCCAGAGAATGGTTCTTCTTACTGTCCAAAGAG ATGTTCAACCCCTACTACGGCCTCTTTGAGTACTCTGCCACTGCAGGGGACAACTCCACTGTTTCCTTTGCCATCGTGCAAGCCAGTCCG AAGGACCAGGGACTCTATTACTGCTGCATCAAGAACAGCTACGGAAAAGTGACTGCTGAATTTAACCTCACAGCTGAAGTTCTCAAACAG CTGTCAAGTCGCCAGGATACTAAAGGATGTGAAGAGATTGAATTCAGCCAACTCATCTTCAAAGAAGACTTCCTCCATGACAGCTACTTT GGGGGCCGCCTGCGTGGTCAGATCGCCACGGAGGAGCTGCACTTTGGAGAAGGGGTTCACCGCAAAGCCTTCCGCAGCACAGTGATGCAC GGCCTCATGCCTGTCTTCAAACCTGGCCATGCCTGTGTGCTTAAGGTGCACAATGCCATTGCCTATGGGACCAGAAATAATGATGAGCTC ATCCAAAGGAACTACAAACTCGCTGCCCAGGAATGCTATGTTCAAAATACTGCCAGGTATTATGCCAAGATCTACGCTGCTGAAGCACAG CCTCTGGAAGGCTTTGGAGAAGTACCTGAGATCATTCCTATTTTTCTTATCCATCGGCCTGAGAACAATATCCCGTATGCTACAGTGGAG GAGGAGCTGATTGGAGAATTTGTGAAGTATTCCATCAGGGATGGGAAAGAAATAAACTTCTTGAGAAGAGAATCAGAAGCTGGTCAGAAA TGTTGCACCTTCCAGCACTGGGTGTACCAGAAAACAAGTGGCTGCCTCCTGGTGACGGACATGCAAGGTGTAGGAATGAAGCTAACTGAC GTTGGCATAGCAACGCTGGCTAAAGGGTACAAGGGATTTAAAGGCAACTGTTCCATGACCTTCATTGATCAGTTTAAAGCACTACACCAG TGTAACAAGTATTGCAAAATGCTGGGACTGAAATCCCTTCAAAACAACAACCAGAAACAGAAGCAGCCGAGCATTGGGAAAAGCAAAGTT CAAACAAACTCTATGACAATAAAGAAGGCAGGGCCTGAGACCCCAGGCGAAAAGAAAACCTAACGTCCCTGGGTAACCTAATGGCCACTG GCTAGCAGCACACAATCTCGCCAGGGAAAATCTGAGGCCACACAGGAGAGAATATACAGCCTGCAGAGAGTGCGTGGCAATCCTTACTCC CAGCCGACTGTGCGCCAAGATGCTTCTAAACCCATCACCTGCTGTCTTCACTCAAATGATTTCAGAACAGGATTTGCGACCAGGTTTATG GGGAGATTGAATCAACGATTGGTCTCAAAGACAGTCCATTCTTTATATACATGTTTAGCATTTTTACCAACCTCACATCATGTGTATATT TGTGTATTTGCACATGGTTGTGCTGTCGAGGACCTGGTGCTGAGAAGAGTCTGTTCACAGCCAAAATTCTTCCCACTGTCATTCCTAACC TGGGATTTCTAGACACATCCTGCTGTGATGTAAACAGAAATCACGAATTCGCTCACTGGATCAAGTTGTTCCACTGGTGTCTAATACGCT ATTGTTGCCGGAGGTGGGTTCTGTGACGTGAAGCCATTTCCCATCATTCAACAGCCAGTTACAATTTTCTGTTTAATTAAATTCATATTT >58409_58409_1_NEDD4L-ALPK2_NEDD4L_chr18_56033460_ENST00000256830_ALPK2_chr18_56191294_ENST00000361673_length(amino acids)=920AA_BP=584 MATGLGEPVYGLSEDEGESRILRVKVVSGIDLAKKDIFGASDPYVKLSLYVADENRELALVQTKTIKKTLNPKWNEEFYFRVNPSNHRLL FEVFDENRLTRDDFLGQVDVPLSHLPTEDPTMERPYTFKDFLLRPRSHKSRVKGFLRLKMAYMPKNGGQDEENSDQRDDMEHGWEVVDSN DSASQHQEELPPPPLPPGWEEKVDNLGRTYYVNHNNRTTQWHRPSLMDVSSESDNNIRQINQEAAHRRFRSRRHISEDLEPEPSEGGDVP EPWETISEEVNIAGDSLGLALPPPPASPGSRTSPQELSEELSRRLQITPDSNGEQFSSLIQREPSSRLRSCSVTDAVAEQGHLPPGAKDS PVRRAVKDTLSNPQSPQPSPYNSPKPQHKVTQSFLPPGWEMRIAPNGRPFFIDHNTKTTTWEDPRLKFPVHMRSKTSLNPNDLGPLPPGW EERIHLDGRTFYIDHNSKITQWEDPRLQNPAITGPAVPYSREFKQKYDYFRKKLKKPADIPNRFEMKLHRNNIFEESYRRIMSVKRPDVL KARLWIEFESEKGLDYGGVAREWFFLLSKEMFNPYYGLFEYSATAGDNSTVSFAIVQASPKDQGLYYCCIKNSYGKVTAEFNLTAEVLKQ LSSRQDTKGCEEIEFSQLIFKEDFLHDSYFGGRLRGQIATEELHFGEGVHRKAFRSTVMHGLMPVFKPGHACVLKVHNAIAYGTRNNDEL IQRNYKLAAQECYVQNTARYYAKIYAAEAQPLEGFGEVPEIIPIFLIHRPENNIPYATVEEELIGEFVKYSIRDGKEINFLRRESEAGQK CCTFQHWVYQKTSGCLLVTDMQGVGMKLTDVGIATLAKGYKGFKGNCSMTFIDQFKALHQCNKYCKMLGLKSLQNNNQKQKQPSIGKSKV -------------------------------------------------------------- >58409_58409_2_NEDD4L-ALPK2_NEDD4L_chr18_56033460_ENST00000256832_ALPK2_chr18_56191294_ENST00000361673_length(transcript)=3868nt_BP=2280nt GAGAGGCGCCGGGGCTGCCGCCCGGTGCTCGGCGCGCTCTCGGGAGCCGCCCGCCCGCTGGTCCCGCAGCCTTCCGGGAGGAAGCGGTGC CGGCAGCGTCCAGGGCGCGCTCTCGGGCACCCTCACCTGCCGGCGCCCGGCCGCTTACCCGGCAGGGCGTGCGCAGGGTAGGGTGCGGGA CCGGGGGGACCTGGAGGCAGAGGGGAGAACCGGCCGTCCGCGCCGCAGCACAGCCGCTGGGAGCGCCTCAGACCCCGCGCGGGGCGCCGG CTCCATGGCGACCGGGCTCGGGGAGCCGGTCTATGGACTTTCCGAAGACGAGGGAGAGTCCCGTATTCTCAGAGTAAAAGTTGTTTCTGG AATTGATCTCGCCAAAAAGGACATCTTTGGAGCCAGTGATCCGTATGTGAAACTTTCATTGTACGTAGCGGATGAGAATAGAGAACTTGC TTTGGTCCAGACAAAAACAATTAAAAAGACACTGAACCCAAAATGGAATGAAGAATTTTATTTCAGGGTAAACCCATCTAATCACAGACT CCTATTTGAAGTATTTGACGAAAATAGACTGACACGAGACGACTTCCTGGGCCAGGTGGACGTGCCCCTTAGTCACCTTCCGACAGAAGA TCCAACCATGGAGCGACCCTATACATTTAAGGACTTTCTCCTCAGACCAAGAAGTCATAAGTCTCGAGTTAAGGGATTTTTGCGATTGAA AATGGCCTATATGCCAAAAAATGGAGGTCAAGATGAAGAAAACAGTGACCAGAGGGATGACATGGAGCATGGATGGGAAGTTGTTGACTC AAATGACTCGGCTTCTCAGCACCAAGAGGAACTTCCTCCTCCTCCTCTGCCTCCCGGGTGGGAAGAAAAAGTGGACAATTTAGGCCGAAC TTACTATGTCAACCACAACAACCGGACCACTCAGTGGCACAGACCAAGCCTGATGGACGTGTCCTCGGAGTCGGACAATAACATCAGACA GATCAACCAGGAGGCAGCACACCGGCGCTTCCGCTCCCGCAGGCACATCAGCGAAGACTTGGAGCCCGAGCCCTCGGAGGGCGGGGATGT CCCCGAGCCTTGGGAGACCATTTCAGAGGAAGTGAATATCGCTGGAGACTCTCTCGGTCTGGCTCTGCCCCCACCACCGGCCTCCCCAGG ATCTCGGACCAGCCCTCAGGAGCTGTCAGAGGAACTAAGCAGAAGGCTTCAGATCACTCCAGACTCCAATGGGGAACAGTTCAGCTCTTT GATTCAAAGAGAACCCTCCTCAAGGTTGAGGTCATGCAGTGTCACCGACGCAGTTGCAGAACAGGGCCATCTACCACCGCCATCAGTGGC CTATGTACATACCACGCCGGGTCTGCCTTCAGGCTGGGAAGAAAGAAAAGATGCTAAGGGGCGCACATACTATGTCAATCATAACAATCG AACCACAACTTGGACTCGACCTATCATGCAGCTTGCAGAAGATGGTGCGTCCGGATCAGCCACAAACAGTAACAACCATCTAATCGAGCC TCAGATCCGCCGGCCTCGTAGCCTCAGCTCGCCAACAGTAACTTTATCTGCCCCGCTGGAGGGTGCCAAGGACTCACCCGTACGTCGGGC TGTGAAAGACACCCTTTCCAACCCACAGTCCCCACAGCCATCACCTTACAACTCCCCCAAACCACAACACAAAGTCACACAGAGCTTCTT GCCACCCGGCTGGGAAATGAGGATAGCGCCAAACGGCCGGCCCTTCTTCATTGATCATAACACAAAGACTACAACCTGGGAAGATCCACG TTTGAAATTTCCAGTACATATGCGGTCAAAGACATCTTTAAACCCCAATGACCTTGGCCCCCTTCCTCCTGGCTGGGAAGAAAGAATTCA CTTGGATGGCCGAACGTTTTATATTGATCATAATAGCAAAATTACTCAGTGGGAAGACCCAAGACTGCAGAACCCAGCTATTACTGGTCC GAAAGCTGTCCCTTACTCCAGAGAATTTAAGCAGAAATATGACTACTTCAGGAAGAAATTAAAGAAACCTGCTGATATCCCCAATAGGTT TGAAATGAAACTTCACAGAAATAACATATTTGAAGAGTCCTATCGGAGAATTATGTCCGTGAAAAGACCAGATGTCCTAAAAGCTAGACT GTGGATTGAGTTTGAATCAGAGAAAGGTCTTGACTATGGGGGTGTGGCCAGAGAATGGTTCTTCTTACTGTCCAAAGAGATGTTCAACCC CTACTACGGCCTCTTTGAGTACTCTGCCACTGCAGGGGACAACTCCACTGTTTCCTTTGCCATCGTGCAAGCCAGTCCGAAGGACCAGGG ACTCTATTACTGCTGCATCAAGAACAGCTACGGAAAAGTGACTGCTGAATTTAACCTCACAGCTGAAGTTCTCAAACAGCTGTCAAGTCG CCAGGATACTAAAGGATGTGAAGAGATTGAATTCAGCCAACTCATCTTCAAAGAAGACTTCCTCCATGACAGCTACTTTGGGGGCCGCCT GCGTGGTCAGATCGCCACGGAGGAGCTGCACTTTGGAGAAGGGGTTCACCGCAAAGCCTTCCGCAGCACAGTGATGCACGGCCTCATGCC TGTCTTCAAACCTGGCCATGCCTGTGTGCTTAAGGTGCACAATGCCATTGCCTATGGGACCAGAAATAATGATGAGCTCATCCAAAGGAA CTACAAACTCGCTGCCCAGGAATGCTATGTTCAAAATACTGCCAGGTATTATGCCAAGATCTACGCTGCTGAAGCACAGCCTCTGGAAGG CTTTGGAGAAGTACCTGAGATCATTCCTATTTTTCTTATCCATCGGCCTGAGAACAATATCCCGTATGCTACAGTGGAGGAGGAGCTGAT TGGAGAATTTGTGAAGTATTCCATCAGGGATGGGAAAGAAATAAACTTCTTGAGAAGAGAATCAGAAGCTGGTCAGAAATGTTGCACCTT CCAGCACTGGGTGTACCAGAAAACAAGTGGCTGCCTCCTGGTGACGGACATGCAAGGTGTAGGAATGAAGCTAACTGACGTTGGCATAGC AACGCTGGCTAAAGGGTACAAGGGATTTAAAGGCAACTGTTCCATGACCTTCATTGATCAGTTTAAAGCACTACACCAGTGTAACAAGTA TTGCAAAATGCTGGGACTGAAATCCCTTCAAAACAACAACCAGAAACAGAAGCAGCCGAGCATTGGGAAAAGCAAAGTTCAAACAAACTC TATGACAATAAAGAAGGCAGGGCCTGAGACCCCAGGCGAAAAGAAAACCTAACGTCCCTGGGTAACCTAATGGCCACTGGCTAGCAGCAC ACAATCTCGCCAGGGAAAATCTGAGGCCACACAGGAGAGAATATACAGCCTGCAGAGAGTGCGTGGCAATCCTTACTCCCAGCCGACTGT GCGCCAAGATGCTTCTAAACCCATCACCTGCTGTCTTCACTCAAATGATTTCAGAACAGGATTTGCGACCAGGTTTATGGGGAGATTGAA TCAACGATTGGTCTCAAAGACAGTCCATTCTTTATATACATGTTTAGCATTTTTACCAACCTCACATCATGTGTATATTTGTGTATTTGC ACATGGTTGTGCTGTCGAGGACCTGGTGCTGAGAAGAGTCTGTTCACAGCCAAAATTCTTCCCACTGTCATTCCTAACCTGGGATTTCTA GACACATCCTGCTGTGATGTAAACAGAAATCACGAATTCGCTCACTGGATCAAGTTGTTCCACTGGTGTCTAATACGCTATTGTTGCCGG >58409_58409_2_NEDD4L-ALPK2_NEDD4L_chr18_56033460_ENST00000256832_ALPK2_chr18_56191294_ENST00000361673_length(amino acids)=1033AA_BP=697 MEAEGRTGRPRRSTAAGSASDPARGAGSMATGLGEPVYGLSEDEGESRILRVKVVSGIDLAKKDIFGASDPYVKLSLYVADENRELALVQ TKTIKKTLNPKWNEEFYFRVNPSNHRLLFEVFDENRLTRDDFLGQVDVPLSHLPTEDPTMERPYTFKDFLLRPRSHKSRVKGFLRLKMAY MPKNGGQDEENSDQRDDMEHGWEVVDSNDSASQHQEELPPPPLPPGWEEKVDNLGRTYYVNHNNRTTQWHRPSLMDVSSESDNNIRQINQ EAAHRRFRSRRHISEDLEPEPSEGGDVPEPWETISEEVNIAGDSLGLALPPPPASPGSRTSPQELSEELSRRLQITPDSNGEQFSSLIQR EPSSRLRSCSVTDAVAEQGHLPPPSVAYVHTTPGLPSGWEERKDAKGRTYYVNHNNRTTTWTRPIMQLAEDGASGSATNSNNHLIEPQIR RPRSLSSPTVTLSAPLEGAKDSPVRRAVKDTLSNPQSPQPSPYNSPKPQHKVTQSFLPPGWEMRIAPNGRPFFIDHNTKTTTWEDPRLKF PVHMRSKTSLNPNDLGPLPPGWEERIHLDGRTFYIDHNSKITQWEDPRLQNPAITGPKAVPYSREFKQKYDYFRKKLKKPADIPNRFEMK LHRNNIFEESYRRIMSVKRPDVLKARLWIEFESEKGLDYGGVAREWFFLLSKEMFNPYYGLFEYSATAGDNSTVSFAIVQASPKDQGLYY CCIKNSYGKVTAEFNLTAEVLKQLSSRQDTKGCEEIEFSQLIFKEDFLHDSYFGGRLRGQIATEELHFGEGVHRKAFRSTVMHGLMPVFK PGHACVLKVHNAIAYGTRNNDELIQRNYKLAAQECYVQNTARYYAKIYAAEAQPLEGFGEVPEIIPIFLIHRPENNIPYATVEEELIGEF VKYSIRDGKEINFLRRESEAGQKCCTFQHWVYQKTSGCLLVTDMQGVGMKLTDVGIATLAKGYKGFKGNCSMTFIDQFKALHQCNKYCKM -------------------------------------------------------------- >58409_58409_3_NEDD4L-ALPK2_NEDD4L_chr18_56033460_ENST00000356462_ALPK2_chr18_56191294_ENST00000361673_length(transcript)=3753nt_BP=2165nt GCGCCGCCGCCGCGCGCAGTGAGAGGCGCCGGGGCTGCCGCCCGGTGCTCGGCGCGCTCTCGGGAGCCGCCCGCCCGCTGGTCCCGCAGC CTTCCGGGAGGAAGCGGTGCCGGCAGCGTCCAGGGCGCGCTCTCGGGCACCCTCACCTGCCGGCGCCCGGCCGCTTACCCGGCAGGGCGT GCGCAGGGTAGGGTGCGGGACCGGGGGGACCTGGAGGCAGAGGGGAGAACCGGCCGTCCGCGCCGCAGCACAGCCGCTGGGAGCGCCTCA GACCCCGCGCGGGGCGCCGGCTCCATGGCGACCGGGCTCGGGGAGCCGGTCTATGGACTTTCCGAAGACGAGGGAGAGTCCCGTATTCTC AGAGTAAAAGTTGTTTCTGGAATTGATCTCGCCAAAAAGGACATCTTTGGAGCCAGTGATCCGTATGTGAAACTTTCATTGTACGTAGCG GATGAGAATAGAGAACTTGCTTTGGTCCAGACAAAAACAATTAAAAAGACACTGAACCCAAAATGGAATGAAGAATTTTATTTCAGGGTA AACCCATCTAATCACAGACTCCTATTTGAAGTATTTGACGAAAATAGACTGACACGAGACGACTTCCTGGGCCAGGTGGACGTGCCCCTT AGTCACCTTCCGACAGAAGATCCAACCATGGAGCGACCCTATACATTTAAGGACTTTCTCCTCAGACCAAGAAGTCATAAGTCTCGAGTT AAGGGATTTTTGCGATTGAAAATGGCCTATATGCCAAAAAATGGAGGTCAAGATGAAGAAAACAGTGACCAGAGGGATGACATGGAGCAT GGATGGGAAGTTGTTGACTCAAATGACTCGGCTTCTCAGCACCAAGAGGAACTTCCTCCTCCTCCTCTGCCTCCCGGGTGGGAAGAAAAA GTGGACAATTTAGGCCGAACTTACTATGTCAACCACAACAACCGGACCACTCAGTGGCACAGACCAAGCCTGATGGACGTGTCCTCGGAG TCGGACAATAACATCAGACAGATCAACCAGGAGGCAGCACACCGGCGCTTCCGCTCCCGCAGGCACATCAGCGAAGACTTGGAGCCCGAG CCCTCGGAGGGCGGGGATGTCCCCGAGCCTTGGGAGACCATTTCAGAGGAAGTGAATATCGCTGGAGACTCTCTCGGTCTGGCTCTGCCC CCACCACCGGCCTCCCCAGGATCTCGGACCAGCCCTCAGGAGCTGTCAGAGGAACTAAGCAGAAGGCTTCAGATCACTCCAGACTCCAAT GGGGAACAGTTCAGCTCTTTGATTCAAAGAGAACCCTCCTCAAGGTTGAGGTCATGCAGTGTCACCGACGCAGTTGCAGAACAGGGCCAT CTACCACCGCTTGCAGAAGATGGTGCGTCCGGATCAGCCACAAACAGTAACAACCATCTAATCGAGCCTCAGATCCGCCGGCCTCGTAGC CTCAGCTCGCCAACAGTAACTTTATCTGCCCCGCTGGAGGGTGCCAAGGACTCACCCGTACGTCGGGCTGTGAAAGACACCCTTTCCAAC CCACAGTCCCCACAGCCATCACCTTACAACTCCCCCAAACCACAACACAAAGTCACACAGAGCTTCTTGCCACCCGGCTGGGAAATGAGG ATAGCGCCAAACGGCCGGCCCTTCTTCATTGATCATAACACAAAGACTACAACCTGGGAAGATCCACGTTTGAAATTTCCAGTACATATG CGGTCAAAGACATCTTTAAACCCCAATGACCTTGGCCCCCTTCCTCCTGGCTGGGAAGAAAGAATTCACTTGGATGGCCGAACGTTTTAT ATTGATCATAATAGCAAAATTACTCAGTGGGAAGACCCAAGACTGCAGAACCCAGCTATTACTGGTCCGGCTGTCCCTTACTCCAGAGAA TTTAAGCAGAAATATGACTACTTCAGGAAGAAATTAAAGAAACCTGCTGATATCCCCAATAGGTTTGAAATGAAACTTCACAGAAATAAC ATATTTGAAGAGTCCTATCGGAGAATTATGTCCGTGAAAAGACCAGATGTCCTAAAAGCTAGACTGTGGATTGAGTTTGAATCAGAGAAA GGTCTTGACTATGGGGGTGTGGCCAGAGAATGGTTCTTCTTACTGTCCAAAGAGATGTTCAACCCCTACTACGGCCTCTTTGAGTACTCT GCCACTGCAGGGGACAACTCCACTGTTTCCTTTGCCATCGTGCAAGCCAGTCCGAAGGACCAGGGACTCTATTACTGCTGCATCAAGAAC AGCTACGGAAAAGTGACTGCTGAATTTAACCTCACAGCTGAAGTTCTCAAACAGCTGTCAAGTCGCCAGGATACTAAAGGATGTGAAGAG ATTGAATTCAGCCAACTCATCTTCAAAGAAGACTTCCTCCATGACAGCTACTTTGGGGGCCGCCTGCGTGGTCAGATCGCCACGGAGGAG CTGCACTTTGGAGAAGGGGTTCACCGCAAAGCCTTCCGCAGCACAGTGATGCACGGCCTCATGCCTGTCTTCAAACCTGGCCATGCCTGT GTGCTTAAGGTGCACAATGCCATTGCCTATGGGACCAGAAATAATGATGAGCTCATCCAAAGGAACTACAAACTCGCTGCCCAGGAATGC TATGTTCAAAATACTGCCAGGTATTATGCCAAGATCTACGCTGCTGAAGCACAGCCTCTGGAAGGCTTTGGAGAAGTACCTGAGATCATT CCTATTTTTCTTATCCATCGGCCTGAGAACAATATCCCGTATGCTACAGTGGAGGAGGAGCTGATTGGAGAATTTGTGAAGTATTCCATC AGGGATGGGAAAGAAATAAACTTCTTGAGAAGAGAATCAGAAGCTGGTCAGAAATGTTGCACCTTCCAGCACTGGGTGTACCAGAAAACA AGTGGCTGCCTCCTGGTGACGGACATGCAAGGTGTAGGAATGAAGCTAACTGACGTTGGCATAGCAACGCTGGCTAAAGGGTACAAGGGA TTTAAAGGCAACTGTTCCATGACCTTCATTGATCAGTTTAAAGCACTACACCAGTGTAACAAGTATTGCAAAATGCTGGGACTGAAATCC CTTCAAAACAACAACCAGAAACAGAAGCAGCCGAGCATTGGGAAAAGCAAAGTTCAAACAAACTCTATGACAATAAAGAAGGCAGGGCCT GAGACCCCAGGCGAAAAGAAAACCTAACGTCCCTGGGTAACCTAATGGCCACTGGCTAGCAGCACACAATCTCGCCAGGGAAAATCTGAG GCCACACAGGAGAGAATATACAGCCTGCAGAGAGTGCGTGGCAATCCTTACTCCCAGCCGACTGTGCGCCAAGATGCTTCTAAACCCATC ACCTGCTGTCTTCACTCAAATGATTTCAGAACAGGATTTGCGACCAGGTTTATGGGGAGATTGAATCAACGATTGGTCTCAAAGACAGTC CATTCTTTATATACATGTTTAGCATTTTTACCAACCTCACATCATGTGTATATTTGTGTATTTGCACATGGTTGTGCTGTCGAGGACCTG GTGCTGAGAAGAGTCTGTTCACAGCCAAAATTCTTCCCACTGTCATTCCTAACCTGGGATTTCTAGACACATCCTGCTGTGATGTAAACA GAAATCACGAATTCGCTCACTGGATCAAGTTGTTCCACTGGTGTCTAATACGCTATTGTTGCCGGAGGTGGGTTCTGTGACGTGAAGCCA >58409_58409_3_NEDD4L-ALPK2_NEDD4L_chr18_56033460_ENST00000356462_ALPK2_chr18_56191294_ENST00000361673_length(amino acids)=988AA_BP=652 MEAEGRTGRPRRSTAAGSASDPARGAGSMATGLGEPVYGLSEDEGESRILRVKVVSGIDLAKKDIFGASDPYVKLSLYVADENRELALVQ TKTIKKTLNPKWNEEFYFRVNPSNHRLLFEVFDENRLTRDDFLGQVDVPLSHLPTEDPTMERPYTFKDFLLRPRSHKSRVKGFLRLKMAY MPKNGGQDEENSDQRDDMEHGWEVVDSNDSASQHQEELPPPPLPPGWEEKVDNLGRTYYVNHNNRTTQWHRPSLMDVSSESDNNIRQINQ EAAHRRFRSRRHISEDLEPEPSEGGDVPEPWETISEEVNIAGDSLGLALPPPPASPGSRTSPQELSEELSRRLQITPDSNGEQFSSLIQR EPSSRLRSCSVTDAVAEQGHLPPLAEDGASGSATNSNNHLIEPQIRRPRSLSSPTVTLSAPLEGAKDSPVRRAVKDTLSNPQSPQPSPYN SPKPQHKVTQSFLPPGWEMRIAPNGRPFFIDHNTKTTTWEDPRLKFPVHMRSKTSLNPNDLGPLPPGWEERIHLDGRTFYIDHNSKITQW EDPRLQNPAITGPAVPYSREFKQKYDYFRKKLKKPADIPNRFEMKLHRNNIFEESYRRIMSVKRPDVLKARLWIEFESEKGLDYGGVARE WFFLLSKEMFNPYYGLFEYSATAGDNSTVSFAIVQASPKDQGLYYCCIKNSYGKVTAEFNLTAEVLKQLSSRQDTKGCEEIEFSQLIFKE DFLHDSYFGGRLRGQIATEELHFGEGVHRKAFRSTVMHGLMPVFKPGHACVLKVHNAIAYGTRNNDELIQRNYKLAAQECYVQNTARYYA KIYAAEAQPLEGFGEVPEIIPIFLIHRPENNIPYATVEEELIGEFVKYSIRDGKEINFLRRESEAGQKCCTFQHWVYQKTSGCLLVTDMQ -------------------------------------------------------------- >58409_58409_4_NEDD4L-ALPK2_NEDD4L_chr18_56033460_ENST00000357895_ALPK2_chr18_56191294_ENST00000361673_length(transcript)=3830nt_BP=2242nt GCCATTTCCAGAGAGGAACAACCGTGTAGACTGCTTTCCTGGGAGTCAAGTTAAAACTTCTCTCCTGTGACCTTGTCACCCGGCAGTGGA AAGTTACCCTTGGCTGCAGCCACGACTTCCGCATACTCTTCAGAACTTGCTCTGCCCTTGAGTTTTCCAGCTTTCCTTTAATGCACTAAA CCTTTAATATTGTATTCTCCTAAATGAGACGTCTCGCATTTGAGCAGGGAGAGTCCCGTATTCTCAGAGTAAAAGTTGTTTCTGGAATTG ATCTCGCCAAAAAGGACATCTTTGGAGCCAGTGATCCGTATGTGAAACTTTCATTGTACGTAGCGGATGAGAATAGAGAACTTGCTTTGG TCCAGACAAAAACAATTAAAAAGACACTGAACCCAAAATGGAATGAAGAATTTTATTTCAGGGTAAACCCATCTAATCACAGACTCCTAT TTGAAGTATTTGACGAAAATAGACTGACACGAGACGACTTCCTGGGCCAGGTGGACGTGCCCCTTAGTCACCTTCCGACAGAAGATCCAA CCATGGAGCGACCCTATACATTTAAGGACTTTCTCCTCAGACCAAGAAGTCATAAGTCTCGAGTTAAGGGATTTTTGCGATTGAAAATGG CCTATATGCCAAAAAATGGAGGTCAAGATGAAGAAAACAGTGACCAGAGGGATGACATGGAGCATGGATGGGAAGTTGTTGACTCAAATG ACTCGGCTTCTCAGCACCAAGAGGAACTTCCTCCTCCTCCTCTGCCTCCCGGGTGGGAAGAAAAAGTGGACAATTTAGGCCGAACTTACT ATGTCAACCACAACAACCGGACCACTCAGTGGCACAGACCAAGCCTGATGGACGTGTCCTCGGAGTCGGACAATAACATCAGACAGATCA ACCAGGAGGCAGCACACCGGCGCTTCCGCTCCCGCAGGCACATCAGCGAAGACTTGGAGCCCGAGCCCTCGGAGGGCGGGGATGTCCCCG AGCCTTGGGAGACCATTTCAGAGGAAGTGAATATCGCTGGAGACTCTCTCGGTCTGGCTCTGCCCCCACCACCGGCCTCCCCAGGATCTC GGACCAGCCCTCAGGAGCTGTCAGAGGAACTAAGCAGAAGGCTTCAGATCACTCCAGACTCCAATGGGGAACAGTTCAGCTCTTTGATTC AAAGAGAACCCTCCTCAAGGTTGAGGTCATGCAGTGTCACCGACGCAGTTGCAGAACAGGGCCATCTACCACCGCCCAGTGCCCCAGCTG GGAGAGCGCGTTCATCAACTGTCACGGGTGGTGAGGAACCAACGCCATCAGTGGCCTATGTACATACCACGCCGGGTCTGCCTTCAGGCT GGGAAGAAAGAAAAGATGCTAAGGGGCGCACATACTATGTCAATCATAACAATCGAACCACAACTTGGACTCGACCTATCATGCAGCTTG CAGAAGATGGTGCGTCCGGATCAGCCACAAACAGTAACAACCATCTAATCGAGCCTCAGATCCGCCGGCCTCGTAGCCTCAGCTCGCCAA CAGTAACTTTATCTGCCCCGCTGGAGGGTGCCAAGGACTCACCCGTACGTCGGGCTGTGAAAGACACCCTTTCCAACCCACAGTCCCCAC AGCCATCACCTTACAACTCCCCCAAACCACAACACAAAGTCACACAGAGCTTCTTGCCACCCGGCTGGGAAATGAGGATAGCGCCAAACG GCCGGCCCTTCTTCATTGATCATAACACAAAGACTACAACCTGGGAAGATCCACGTTTGAAATTTCCAGTACATATGCGGTCAAAGACAT CTTTAAACCCCAATGACCTTGGCCCCCTTCCTCCTGGCTGGGAAGAAAGAATTCACTTGGATGGCCGAACGTTTTATATTGATCATAATA GCAAAATTACTCAGTGGGAAGACCCAAGACTGCAGAACCCAGCTATTACTGGTCCGGCTGTCCCTTACTCCAGAGAATTTAAGCAGAAAT ATGACTACTTCAGGAAGAAATTAAAGAAACCTGCTGATATCCCCAATAGGTTTGAAATGAAACTTCACAGAAATAACATATTTGAAGAGT CCTATCGGAGAATTATGTCCGTGAAAAGACCAGATGTCCTAAAAGCTAGACTGTGGATTGAGTTTGAATCAGAGAAAGGTCTTGACTATG GGGGTGTGGCCAGAGAATGGTTCTTCTTACTGTCCAAAGAGATGTTCAACCCCTACTACGGCCTCTTTGAGTACTCTGCCACTGCAGGGG ACAACTCCACTGTTTCCTTTGCCATCGTGCAAGCCAGTCCGAAGGACCAGGGACTCTATTACTGCTGCATCAAGAACAGCTACGGAAAAG TGACTGCTGAATTTAACCTCACAGCTGAAGTTCTCAAACAGCTGTCAAGTCGCCAGGATACTAAAGGATGTGAAGAGATTGAATTCAGCC AACTCATCTTCAAAGAAGACTTCCTCCATGACAGCTACTTTGGGGGCCGCCTGCGTGGTCAGATCGCCACGGAGGAGCTGCACTTTGGAG AAGGGGTTCACCGCAAAGCCTTCCGCAGCACAGTGATGCACGGCCTCATGCCTGTCTTCAAACCTGGCCATGCCTGTGTGCTTAAGGTGC ACAATGCCATTGCCTATGGGACCAGAAATAATGATGAGCTCATCCAAAGGAACTACAAACTCGCTGCCCAGGAATGCTATGTTCAAAATA CTGCCAGGTATTATGCCAAGATCTACGCTGCTGAAGCACAGCCTCTGGAAGGCTTTGGAGAAGTACCTGAGATCATTCCTATTTTTCTTA TCCATCGGCCTGAGAACAATATCCCGTATGCTACAGTGGAGGAGGAGCTGATTGGAGAATTTGTGAAGTATTCCATCAGGGATGGGAAAG AAATAAACTTCTTGAGAAGAGAATCAGAAGCTGGTCAGAAATGTTGCACCTTCCAGCACTGGGTGTACCAGAAAACAAGTGGCTGCCTCC TGGTGACGGACATGCAAGGTGTAGGAATGAAGCTAACTGACGTTGGCATAGCAACGCTGGCTAAAGGGTACAAGGGATTTAAAGGCAACT GTTCCATGACCTTCATTGATCAGTTTAAAGCACTACACCAGTGTAACAAGTATTGCAAAATGCTGGGACTGAAATCCCTTCAAAACAACA ACCAGAAACAGAAGCAGCCGAGCATTGGGAAAAGCAAAGTTCAAACAAACTCTATGACAATAAAGAAGGCAGGGCCTGAGACCCCAGGCG AAAAGAAAACCTAACGTCCCTGGGTAACCTAATGGCCACTGGCTAGCAGCACACAATCTCGCCAGGGAAAATCTGAGGCCACACAGGAGA GAATATACAGCCTGCAGAGAGTGCGTGGCAATCCTTACTCCCAGCCGACTGTGCGCCAAGATGCTTCTAAACCCATCACCTGCTGTCTTC ACTCAAATGATTTCAGAACAGGATTTGCGACCAGGTTTATGGGGAGATTGAATCAACGATTGGTCTCAAAGACAGTCCATTCTTTATATA CATGTTTAGCATTTTTACCAACCTCACATCATGTGTATATTTGTGTATTTGCACATGGTTGTGCTGTCGAGGACCTGGTGCTGAGAAGAG TCTGTTCACAGCCAAAATTCTTCCCACTGTCATTCCTAACCTGGGATTTCTAGACACATCCTGCTGTGATGTAAACAGAAATCACGAATT CGCTCACTGGATCAAGTTGTTCCACTGGTGTCTAATACGCTATTGTTGCCGGAGGTGGGTTCTGTGACGTGAAGCCATTTCCCATCATTC >58409_58409_4_NEDD4L-ALPK2_NEDD4L_chr18_56033460_ENST00000357895_ALPK2_chr18_56191294_ENST00000361673_length(amino acids)=1016AA_BP=680 MRRLAFEQGESRILRVKVVSGIDLAKKDIFGASDPYVKLSLYVADENRELALVQTKTIKKTLNPKWNEEFYFRVNPSNHRLLFEVFDENR LTRDDFLGQVDVPLSHLPTEDPTMERPYTFKDFLLRPRSHKSRVKGFLRLKMAYMPKNGGQDEENSDQRDDMEHGWEVVDSNDSASQHQE ELPPPPLPPGWEEKVDNLGRTYYVNHNNRTTQWHRPSLMDVSSESDNNIRQINQEAAHRRFRSRRHISEDLEPEPSEGGDVPEPWETISE EVNIAGDSLGLALPPPPASPGSRTSPQELSEELSRRLQITPDSNGEQFSSLIQREPSSRLRSCSVTDAVAEQGHLPPPSAPAGRARSSTV TGGEEPTPSVAYVHTTPGLPSGWEERKDAKGRTYYVNHNNRTTTWTRPIMQLAEDGASGSATNSNNHLIEPQIRRPRSLSSPTVTLSAPL EGAKDSPVRRAVKDTLSNPQSPQPSPYNSPKPQHKVTQSFLPPGWEMRIAPNGRPFFIDHNTKTTTWEDPRLKFPVHMRSKTSLNPNDLG PLPPGWEERIHLDGRTFYIDHNSKITQWEDPRLQNPAITGPAVPYSREFKQKYDYFRKKLKKPADIPNRFEMKLHRNNIFEESYRRIMSV KRPDVLKARLWIEFESEKGLDYGGVAREWFFLLSKEMFNPYYGLFEYSATAGDNSTVSFAIVQASPKDQGLYYCCIKNSYGKVTAEFNLT AEVLKQLSSRQDTKGCEEIEFSQLIFKEDFLHDSYFGGRLRGQIATEELHFGEGVHRKAFRSTVMHGLMPVFKPGHACVLKVHNAIAYGT RNNDELIQRNYKLAAQECYVQNTARYYAKIYAAEAQPLEGFGEVPEIIPIFLIHRPENNIPYATVEEELIGEFVKYSIRDGKEINFLRRE SEAGQKCCTFQHWVYQKTSGCLLVTDMQGVGMKLTDVGIATLAKGYKGFKGNCSMTFIDQFKALHQCNKYCKMLGLKSLQNNNQKQKQPS -------------------------------------------------------------- >58409_58409_5_NEDD4L-ALPK2_NEDD4L_chr18_56033460_ENST00000382850_ALPK2_chr18_56191294_ENST00000361673_length(transcript)=3704nt_BP=2116nt CGCAGGGTAGGGTGCGGGACCGGGGGGACCTGGAGGCAGAGGGGAGAACCGGCCGTCCGCGCCGCAGCACAGCCGCTGGGAGCGCCTCAG ACCCCGCGCGGGGCGCCGGCTCCATGGCGACCGGGCTCGGGGAGCCGGTCTATGGACTTTCCGAAGACGAGGGAGAGTCCCGTATTCTCA GAGTAAAAGTTGTTTCTGGAATTGATCTCGCCAAAAAGGACATCTTTGGAGCCAGTGATCCGTATGTGAAACTTTCATTGTACGTAGCGG ATGAGAATAGAGAACTTGCTTTGGTCCAGACAAAAACAATTAAAAAGACACTGAACCCAAAATGGAATGAAGAATTTTATTTCAGGGTAA ACCCATCTAATCACAGACTCCTATTTGAAGTATTTGACGAAAATAGACTGACACGAGACGACTTCCTGGGCCAGGTGGACGTGCCCCTTA GTCACCTTCCGACAGAAGATCCAACCATGGAGCGACCCTATACATTTAAGGACTTTCTCCTCAGACCAAGAAGTCATAAGTCTCGAGTTA AGGGATTTTTGCGATTGAAAATGGCCTATATGCCAAAAAATGGAGGTCAAGATGAAGAAAACAGTGACCAGAGGGATGACATGGAGCATG GATGGGAAGTTGTTGACTCAAATGACTCGGCTTCTCAGCACCAAGAGGAACTTCCTCCTCCTCCTCTGCCTCCCGGGTGGGAAGAAAAAG TGGACAATTTAGGCCGAACTTACTATGTCAACCACAACAACCGGACCACTCAGTGGCACAGACCAAGCCTGATGGACGTGTCCTCGGAGT CGGACAATAACATCAGACAGATCAACCAGGAGGCAGCACACCGGCGCTTCCGCTCCCGCAGGCACATCAGCGAAGACTTGGAGCCCGAGC CCTCGGAGGGCGGGGATGTCCCCGAGCCTTGGGAGACCATTTCAGAGGAAGTGAATATCGCTGGAGACTCTCTCGGTCTGGCTCTGCCCC CACCACCGGCCTCCCCAGGATCTCGGACCAGCCCTCAGGAGCTGTCAGAGGAACTAAGCAGAAGGCTTCAGATCACTCCAGACTCCAATG GGGAACAGTTCAGCTCTTTGATTCAAAGAGAACCCTCCTCAAGGTTGAGGTCATGCAGTGTCACCGACGCAGTTGCAGAACAGGGCCATC TACCACCGCCATCAGTGGCCTATGTACATACCACGCCGGGTCTGCCTTCAGGCTGGGAAGAAAGAAAAGATGCTAAGGGGCGCACATACT ATGTCAATCATAACAATCGAACCACAACTTGGACTCGACCTATCATGCAGCTTGCAGAAGATGGTGCGTCCGGATCAGCCACAAACAGTA ACAACCATCTAATCGAGCCTCAGATCCGCCGGCCTCGTAGCCTCAGCTCGCCAACAGTAACTTTATCTGCCCCGCTGGAGGGTGCCAAGG ACTCACCCGTACGTCGGGCTGTGAAAGACACCCTTTCCAACCCACAGTCCCCACAGCCATCACCTTACAACTCCCCCAAACCACAACACA AAGTCACACAGAGCTTCTTGCCACCCGGCTGGGAAATGAGGATAGCGCCAAACGGCCGGCCCTTCTTCATTGATCATAACACAAAGACTA CAACCTGGGAAGATCCACGTTTGAAATTTCCAGTACATATGCGGTCAAAGACATCTTTAAACCCCAATGACCTTGGCCCCCTTCCTCCTG GCTGGGAAGAAAGAATTCACTTGGATGGCCGAACGTTTTATATTGATCATAATAGCAAAATTACTCAGTGGGAAGACCCAAGACTGCAGA ACCCAGCTATTACTGGTCCGGCTGTCCCTTACTCCAGAGAATTTAAGCAGAAATATGACTACTTCAGGAAGAAATTAAAGAAACCTGCTG ATATCCCCAATAGGTTTGAAATGAAACTTCACAGAAATAACATATTTGAAGAGTCCTATCGGAGAATTATGTCCGTGAAAAGACCAGATG TCCTAAAAGCTAGACTGTGGATTGAGTTTGAATCAGAGAAAGGTCTTGACTATGGGGGTGTGGCCAGAGAATGGTTCTTCTTACTGTCCA AAGAGATGTTCAACCCCTACTACGGCCTCTTTGAGTACTCTGCCACTGCAGGGGACAACTCCACTGTTTCCTTTGCCATCGTGCAAGCCA GTCCGAAGGACCAGGGACTCTATTACTGCTGCATCAAGAACAGCTACGGAAAAGTGACTGCTGAATTTAACCTCACAGCTGAAGTTCTCA AACAGCTGTCAAGTCGCCAGGATACTAAAGGATGTGAAGAGATTGAATTCAGCCAACTCATCTTCAAAGAAGACTTCCTCCATGACAGCT ACTTTGGGGGCCGCCTGCGTGGTCAGATCGCCACGGAGGAGCTGCACTTTGGAGAAGGGGTTCACCGCAAAGCCTTCCGCAGCACAGTGA TGCACGGCCTCATGCCTGTCTTCAAACCTGGCCATGCCTGTGTGCTTAAGGTGCACAATGCCATTGCCTATGGGACCAGAAATAATGATG AGCTCATCCAAAGGAACTACAAACTCGCTGCCCAGGAATGCTATGTTCAAAATACTGCCAGGTATTATGCCAAGATCTACGCTGCTGAAG CACAGCCTCTGGAAGGCTTTGGAGAAGTACCTGAGATCATTCCTATTTTTCTTATCCATCGGCCTGAGAACAATATCCCGTATGCTACAG TGGAGGAGGAGCTGATTGGAGAATTTGTGAAGTATTCCATCAGGGATGGGAAAGAAATAAACTTCTTGAGAAGAGAATCAGAAGCTGGTC AGAAATGTTGCACCTTCCAGCACTGGGTGTACCAGAAAACAAGTGGCTGCCTCCTGGTGACGGACATGCAAGGTGTAGGAATGAAGCTAA CTGACGTTGGCATAGCAACGCTGGCTAAAGGGTACAAGGGATTTAAAGGCAACTGTTCCATGACCTTCATTGATCAGTTTAAAGCACTAC ACCAGTGTAACAAGTATTGCAAAATGCTGGGACTGAAATCCCTTCAAAACAACAACCAGAAACAGAAGCAGCCGAGCATTGGGAAAAGCA AAGTTCAAACAAACTCTATGACAATAAAGAAGGCAGGGCCTGAGACCCCAGGCGAAAAGAAAACCTAACGTCCCTGGGTAACCTAATGGC CACTGGCTAGCAGCACACAATCTCGCCAGGGAAAATCTGAGGCCACACAGGAGAGAATATACAGCCTGCAGAGAGTGCGTGGCAATCCTT ACTCCCAGCCGACTGTGCGCCAAGATGCTTCTAAACCCATCACCTGCTGTCTTCACTCAAATGATTTCAGAACAGGATTTGCGACCAGGT TTATGGGGAGATTGAATCAACGATTGGTCTCAAAGACAGTCCATTCTTTATATACATGTTTAGCATTTTTACCAACCTCACATCATGTGT ATATTTGTGTATTTGCACATGGTTGTGCTGTCGAGGACCTGGTGCTGAGAAGAGTCTGTTCACAGCCAAAATTCTTCCCACTGTCATTCC TAACCTGGGATTTCTAGACACATCCTGCTGTGATGTAAACAGAAATCACGAATTCGCTCACTGGATCAAGTTGTTCCACTGGTGTCTAAT ACGCTATTGTTGCCGGAGGTGGGTTCTGTGACGTGAAGCCATTTCCCATCATTCAACAGCCAGTTACAATTTTCTGTTTAATTAAATTCA >58409_58409_5_NEDD4L-ALPK2_NEDD4L_chr18_56033460_ENST00000382850_ALPK2_chr18_56191294_ENST00000361673_length(amino acids)=1032AA_BP=696 MEAEGRTGRPRRSTAAGSASDPARGAGSMATGLGEPVYGLSEDEGESRILRVKVVSGIDLAKKDIFGASDPYVKLSLYVADENRELALVQ TKTIKKTLNPKWNEEFYFRVNPSNHRLLFEVFDENRLTRDDFLGQVDVPLSHLPTEDPTMERPYTFKDFLLRPRSHKSRVKGFLRLKMAY MPKNGGQDEENSDQRDDMEHGWEVVDSNDSASQHQEELPPPPLPPGWEEKVDNLGRTYYVNHNNRTTQWHRPSLMDVSSESDNNIRQINQ EAAHRRFRSRRHISEDLEPEPSEGGDVPEPWETISEEVNIAGDSLGLALPPPPASPGSRTSPQELSEELSRRLQITPDSNGEQFSSLIQR EPSSRLRSCSVTDAVAEQGHLPPPSVAYVHTTPGLPSGWEERKDAKGRTYYVNHNNRTTTWTRPIMQLAEDGASGSATNSNNHLIEPQIR RPRSLSSPTVTLSAPLEGAKDSPVRRAVKDTLSNPQSPQPSPYNSPKPQHKVTQSFLPPGWEMRIAPNGRPFFIDHNTKTTTWEDPRLKF PVHMRSKTSLNPNDLGPLPPGWEERIHLDGRTFYIDHNSKITQWEDPRLQNPAITGPAVPYSREFKQKYDYFRKKLKKPADIPNRFEMKL HRNNIFEESYRRIMSVKRPDVLKARLWIEFESEKGLDYGGVAREWFFLLSKEMFNPYYGLFEYSATAGDNSTVSFAIVQASPKDQGLYYC CIKNSYGKVTAEFNLTAEVLKQLSSRQDTKGCEEIEFSQLIFKEDFLHDSYFGGRLRGQIATEELHFGEGVHRKAFRSTVMHGLMPVFKP GHACVLKVHNAIAYGTRNNDELIQRNYKLAAQECYVQNTARYYAKIYAAEAQPLEGFGEVPEIIPIFLIHRPENNIPYATVEEELIGEFV KYSIRDGKEINFLRRESEAGQKCCTFQHWVYQKTSGCLLVTDMQGVGMKLTDVGIATLAKGYKGFKGNCSMTFIDQFKALHQCNKYCKML -------------------------------------------------------------- >58409_58409_6_NEDD4L-ALPK2_NEDD4L_chr18_56033460_ENST00000400345_ALPK2_chr18_56191294_ENST00000361673_length(transcript)=3934nt_BP=2346nt GCGCGCAGTGAGAGGCGCCGGGGCTGCCGCCCGGTGCTCGGCGCGCTCTCGGGAGCCGCCCGCCCGCTGGTCCCGCAGCCTTCCGGGAGG AAGCGGTGCCGGCAGCGTCCAGGGCGCGCTCTCGGGCACCCTCACCTGCCGGCGCCCGGCCGCTTACCCGGCAGGGCGTGCGCAGGGTAG GGTGCGGGACCGGGGGGACCTGGAGGCAGAGGGGAGAACCGGCCGTCCGCGCCGCAGCACAGCCGCTGGGAGCGCCTCAGACCCCGCGCG GGGCGCCGGCTCCATGGCGACCGGGCTCGGGGAGCCGGTCTATGGACTTTCCGAAGACGAGGGAGAGTCCCGTATTCTCAGAGTAAAAGT TGTTTCTGGAATTGATCTCGCCAAAAAGGACATCTTTGGAGCCAGTGATCCGTATGTGAAACTTTCATTGTACGTAGCGGATGAGAATAG AGAACTTGCTTTGGTCCAGACAAAAACAATTAAAAAGACACTGAACCCAAAATGGAATGAAGAATTTTATTTCAGGGTAAACCCATCTAA TCACAGACTCCTATTTGAAGTATTTGACGAAAATAGACTGACACGAGACGACTTCCTGGGCCAGGTGGACGTGCCCCTTAGTCACCTTCC GACAGAAGATCCAACCATGGAGCGACCCTATACATTTAAGGACTTTCTCCTCAGACCAAGAAGTCATAAGTCTCGAGTTAAGGGATTTTT GCGATTGAAAATGGCCTATATGCCAAAAAATGGAGGTCAAGATGAAGAAAACAGTGACCAGAGGGATGACATGGAGCATGGATGGGAAGT TGTTGACTCAAATGACTCGGCTTCTCAGCACCAAGAGGAACTTCCTCCTCCTCCTCTGCCTCCCGGGTGGGAAGAAAAAGTGGACAATTT AGGCCGAACTTACTATGTCAACCACAACAACCGGACCACTCAGTGGCACAGACCAAGCCTGATGGACGTGTCCTCGGAGTCGGACAATAA CATCAGACAGATCAACCAGGAGGCAGCACACCGGCGCTTCCGCTCCCGCAGGCACATCAGCGAAGACTTGGAGCCCGAGCCCTCGGAGGG CGGGGATGTCCCCGAGCCTTGGGAGACCATTTCAGAGGAAGTGAATATCGCTGGAGACTCTCTCGGTCTGGCTCTGCCCCCACCACCGGC CTCCCCAGGATCTCGGACCAGCCCTCAGGAGCTGTCAGAGGAACTAAGCAGAAGGCTTCAGATCACTCCAGACTCCAATGGGGAACAGTT CAGCTCTTTGATTCAAAGAGAACCCTCCTCAAGGTTGAGGTCATGCAGTGTCACCGACGCAGTTGCAGAACAGGGCCATCTACCACCGCC CAGTGCCCCAGCTGGGAGAGCGCGTTCATCAACTGTCACGGGTGGTGAGGAACCAACGCCATCAGTGGCCTATGTACATACCACGCCGGG TCTGCCTTCAGGCTGGGAAGAAAGAAAAGATGCTAAGGGGCGCACATACTATGTCAATCATAACAATCGAACCACAACTTGGACTCGACC TATCATGCAGCTTGCAGAAGATGGTGCGTCCGGATCAGCCACAAACAGTAACAACCATCTAATCGAGCCTCAGATCCGCCGGCCTCGTAG CCTCAGCTCGCCAACAGTAACTTTATCTGCCCCGCTGGAGGGTGCCAAGGACTCACCCGTACGTCGGGCTGTGAAAGACACCCTTTCCAA CCCACAGTCCCCACAGCCATCACCTTACAACTCCCCCAAACCACAACACAAAGTCACACAGAGCTTCTTGCCACCCGGCTGGGAAATGAG GATAGCGCCAAACGGCCGGCCCTTCTTCATTGATCATAACACAAAGACTACAACCTGGGAAGATCCACGTTTGAAATTTCCAGTACATAT GCGGTCAAAGACATCTTTAAACCCCAATGACCTTGGCCCCCTTCCTCCTGGCTGGGAAGAAAGAATTCACTTGGATGGCCGAACGTTTTA TATTGATCATAATAGCAAAATTACTCAGTGGGAAGACCCAAGACTGCAGAACCCAGCTATTACTGGTCCGGCTGTCCCTTACTCCAGAGA ATTTAAGCAGAAATATGACTACTTCAGGAAGAAATTAAAGAAACCTGCTGATATCCCCAATAGGTTTGAAATGAAACTTCACAGAAATAA CATATTTGAAGAGTCCTATCGGAGAATTATGTCCGTGAAAAGACCAGATGTCCTAAAAGCTAGACTGTGGATTGAGTTTGAATCAGAGAA AGGTCTTGACTATGGGGGTGTGGCCAGAGAATGGTTCTTCTTACTGTCCAAAGAGATGTTCAACCCCTACTACGGCCTCTTTGAGTACTC TGCCACTGCAGGGGACAACTCCACTGTTTCCTTTGCCATCGTGCAAGCCAGTCCGAAGGACCAGGGACTCTATTACTGCTGCATCAAGAA CAGCTACGGAAAAGTGACTGCTGAATTTAACCTCACAGCTGAAGTTCTCAAACAGCTGTCAAGTCGCCAGGATACTAAAGGATGTGAAGA GATTGAATTCAGCCAACTCATCTTCAAAGAAGACTTCCTCCATGACAGCTACTTTGGGGGCCGCCTGCGTGGTCAGATCGCCACGGAGGA GCTGCACTTTGGAGAAGGGGTTCACCGCAAAGCCTTCCGCAGCACAGTGATGCACGGCCTCATGCCTGTCTTCAAACCTGGCCATGCCTG TGTGCTTAAGGTGCACAATGCCATTGCCTATGGGACCAGAAATAATGATGAGCTCATCCAAAGGAACTACAAACTCGCTGCCCAGGAATG CTATGTTCAAAATACTGCCAGGTATTATGCCAAGATCTACGCTGCTGAAGCACAGCCTCTGGAAGGCTTTGGAGAAGTACCTGAGATCAT TCCTATTTTTCTTATCCATCGGCCTGAGAACAATATCCCGTATGCTACAGTGGAGGAGGAGCTGATTGGAGAATTTGTGAAGTATTCCAT CAGGGATGGGAAAGAAATAAACTTCTTGAGAAGAGAATCAGAAGCTGGTCAGAAATGTTGCACCTTCCAGCACTGGGTGTACCAGAAAAC AAGTGGCTGCCTCCTGGTGACGGACATGCAAGGTGTAGGAATGAAGCTAACTGACGTTGGCATAGCAACGCTGGCTAAAGGGTACAAGGG ATTTAAAGGCAACTGTTCCATGACCTTCATTGATCAGTTTAAAGCACTACACCAGTGTAACAAGTATTGCAAAATGCTGGGACTGAAATC CCTTCAAAACAACAACCAGAAACAGAAGCAGCCGAGCATTGGGAAAAGCAAAGTTCAAACAAACTCTATGACAATAAAGAAGGCAGGGCC TGAGACCCCAGGCGAAAAGAAAACCTAACGTCCCTGGGTAACCTAATGGCCACTGGCTAGCAGCACACAATCTCGCCAGGGAAAATCTGA GGCCACACAGGAGAGAATATACAGCCTGCAGAGAGTGCGTGGCAATCCTTACTCCCAGCCGACTGTGCGCCAAGATGCTTCTAAACCCAT CACCTGCTGTCTTCACTCAAATGATTTCAGAACAGGATTTGCGACCAGGTTTATGGGGAGATTGAATCAACGATTGGTCTCAAAGACAGT CCATTCTTTATATACATGTTTAGCATTTTTACCAACCTCACATCATGTGTATATTTGTGTATTTGCACATGGTTGTGCTGTCGAGGACCT GGTGCTGAGAAGAGTCTGTTCACAGCCAAAATTCTTCCCACTGTCATTCCTAACCTGGGATTTCTAGACACATCCTGCTGTGATGTAAAC AGAAATCACGAATTCGCTCACTGGATCAAGTTGTTCCACTGGTGTCTAATACGCTATTGTTGCCGGAGGTGGGTTCTGTGACGTGAAGCC >58409_58409_6_NEDD4L-ALPK2_NEDD4L_chr18_56033460_ENST00000400345_ALPK2_chr18_56191294_ENST00000361673_length(amino acids)=1052AA_BP=716 MEAEGRTGRPRRSTAAGSASDPARGAGSMATGLGEPVYGLSEDEGESRILRVKVVSGIDLAKKDIFGASDPYVKLSLYVADENRELALVQ TKTIKKTLNPKWNEEFYFRVNPSNHRLLFEVFDENRLTRDDFLGQVDVPLSHLPTEDPTMERPYTFKDFLLRPRSHKSRVKGFLRLKMAY MPKNGGQDEENSDQRDDMEHGWEVVDSNDSASQHQEELPPPPLPPGWEEKVDNLGRTYYVNHNNRTTQWHRPSLMDVSSESDNNIRQINQ EAAHRRFRSRRHISEDLEPEPSEGGDVPEPWETISEEVNIAGDSLGLALPPPPASPGSRTSPQELSEELSRRLQITPDSNGEQFSSLIQR EPSSRLRSCSVTDAVAEQGHLPPPSAPAGRARSSTVTGGEEPTPSVAYVHTTPGLPSGWEERKDAKGRTYYVNHNNRTTTWTRPIMQLAE DGASGSATNSNNHLIEPQIRRPRSLSSPTVTLSAPLEGAKDSPVRRAVKDTLSNPQSPQPSPYNSPKPQHKVTQSFLPPGWEMRIAPNGR PFFIDHNTKTTTWEDPRLKFPVHMRSKTSLNPNDLGPLPPGWEERIHLDGRTFYIDHNSKITQWEDPRLQNPAITGPAVPYSREFKQKYD YFRKKLKKPADIPNRFEMKLHRNNIFEESYRRIMSVKRPDVLKARLWIEFESEKGLDYGGVAREWFFLLSKEMFNPYYGLFEYSATAGDN STVSFAIVQASPKDQGLYYCCIKNSYGKVTAEFNLTAEVLKQLSSRQDTKGCEEIEFSQLIFKEDFLHDSYFGGRLRGQIATEELHFGEG VHRKAFRSTVMHGLMPVFKPGHACVLKVHNAIAYGTRNNDELIQRNYKLAAQECYVQNTARYYAKIYAAEAQPLEGFGEVPEIIPIFLIH RPENNIPYATVEEELIGEFVKYSIRDGKEINFLRRESEAGQKCCTFQHWVYQKTSGCLLVTDMQGVGMKLTDVGIATLAKGYKGFKGNCS -------------------------------------------------------------- >58409_58409_7_NEDD4L-ALPK2_NEDD4L_chr18_56033460_ENST00000431212_ALPK2_chr18_56191294_ENST00000361673_length(transcript)=3752nt_BP=2164nt ATCAGTATAAGTAGCGAGCTGGGCGCATTCCTTCTCAGTTGTGTTAAAACTTGCTGGTATTCCCCCGGTATCAGCAGAGGTGTGTACGGG CACTGCTTTAAAACTGGGAAGGAGGAAGACGAGGCCAGGGAGCCGGAGGGTCACCAAGGTAGATTTCCAGCAGCGCTAGTCCAGCTGAAC ACTTTCCAGCCTTGTTTTTCAGCAGCTTTGAGGAAAAGTATAGTGATCCGTATGTGAAACTTTCATTGTACGTAGCGGATGAGAATAGAG AACTTGCTTTGGTCCAGACAAAAACAATTAAAAAGACACTGAACCCAAAATGGAATGAAGAATTTTATTTCAGGGTAAACCCATCTAATC ACAGACTCCTATTTGAAGTATTTGACGAAAATAGACTGACACGAGACGACTTCCTGGGCCAGGTGGACGTGCCCCTTAGTCACCTTCCGA CAGAAGATCCAACCATGGAGCGACCCTATACATTTAAGGACTTTCTCCTCAGACCAAGAAGTCATAAGTCTCGAGTTAAGGGATTTTTGC GATTGAAAATGGCCTATATGCCAAAAAATGGAGGTCAAGATGAAGAAAACAGTGACCAGAGGGATGACATGGAGCATGGATGGGAAGTTG TTGACTCAAATGACTCGGCTTCTCAGCACCAAGAGGAACTTCCTCCTCCTCCTCTGCCTCCCGGGTGGGAAGAAAAAGTGGACAATTTAG GCCGAACTTACTATGTCAACCACAACAACCGGACCACTCAGTGGCACAGACCAAGCCTGATGGACGTGTCCTCGGAGTCGGACAATAACA TCAGACAGATCAACCAGGAGGCAGCACACCGGCGCTTCCGCTCCCGCAGGCACATCAGCGAAGACTTGGAGCCCGAGCCCTCGGAGGGCG GGGATGTCCCCGAGCCTTGGGAGACCATTTCAGAGGAAGTGAATATCGCTGGAGACTCTCTCGGTCTGGCTCTGCCCCCACCACCGGCCT CCCCAGGATCTCGGACCAGCCCTCAGGAGCTGTCAGAGGAACTAAGCAGAAGGCTTCAGATCACTCCAGACTCCAATGGGGAACAGTTCA GCTCTTTGATTCAAAGAGAACCCTCCTCAAGGTTGAGGTCATGCAGTGTCACCGACGCAGTTGCAGAACAGGGCCATCTACCACCGCCCA GTGCCCCAGCTGGGAGAGCGCGTTCATCAACTGTCACGGGTGGTGAGGAACCAACGCCATCAGTGGCCTATGTACATACCACGCCGGGTC TGCCTTCAGGCTGGGAAGAAAGAAAAGATGCTAAGGGGCGCACATACTATGTCAATCATAACAATCGAACCACAACTTGGACTCGACCTA TCATGCAGCTTGCAGAAGATGGTGCGTCCGGATCAGCCACAAACAGTAACAACCATCTAATCGAGCCTCAGATCCGCCGGCCTCGTAGCC TCAGCTCGCCAACAGTAACTTTATCTGCCCCGCTGGAGGGTGCCAAGGACTCACCCGTACGTCGGGCTGTGAAAGACACCCTTTCCAACC CACAGTCCCCACAGCCATCACCTTACAACTCCCCCAAACCACAACACAAAGTCACACAGAGCTTCTTGCCACCCGGCTGGGAAATGAGGA TAGCGCCAAACGGCCGGCCCTTCTTCATTGATCATAACACAAAGACTACAACCTGGGAAGATCCACGTTTGAAATTTCCAGTACATATGC GGTCAAAGACATCTTTAAACCCCAATGACCTTGGCCCCCTTCCTCCTGGCTGGGAAGAAAGAATTCACTTGGATGGCCGAACGTTTTATA TTGATCATAATAGCAAAATTACTCAGTGGGAAGACCCAAGACTGCAGAACCCAGCTATTACTGGTCCGGCTGTCCCTTACTCCAGAGAAT TTAAGCAGAAATATGACTACTTCAGGAAGAAATTAAAGAAACCTGCTGATATCCCCAATAGGTTTGAAATGAAACTTCACAGAAATAACA TATTTGAAGAGTCCTATCGGAGAATTATGTCCGTGAAAAGACCAGATGTCCTAAAAGCTAGACTGTGGATTGAGTTTGAATCAGAGAAAG GTCTTGACTATGGGGGTGTGGCCAGAGAATGGTTCTTCTTACTGTCCAAAGAGATGTTCAACCCCTACTACGGCCTCTTTGAGTACTCTG CCACTGCAGGGGACAACTCCACTGTTTCCTTTGCCATCGTGCAAGCCAGTCCGAAGGACCAGGGACTCTATTACTGCTGCATCAAGAACA GCTACGGAAAAGTGACTGCTGAATTTAACCTCACAGCTGAAGTTCTCAAACAGCTGTCAAGTCGCCAGGATACTAAAGGATGTGAAGAGA TTGAATTCAGCCAACTCATCTTCAAAGAAGACTTCCTCCATGACAGCTACTTTGGGGGCCGCCTGCGTGGTCAGATCGCCACGGAGGAGC TGCACTTTGGAGAAGGGGTTCACCGCAAAGCCTTCCGCAGCACAGTGATGCACGGCCTCATGCCTGTCTTCAAACCTGGCCATGCCTGTG TGCTTAAGGTGCACAATGCCATTGCCTATGGGACCAGAAATAATGATGAGCTCATCCAAAGGAACTACAAACTCGCTGCCCAGGAATGCT ATGTTCAAAATACTGCCAGGTATTATGCCAAGATCTACGCTGCTGAAGCACAGCCTCTGGAAGGCTTTGGAGAAGTACCTGAGATCATTC CTATTTTTCTTATCCATCGGCCTGAGAACAATATCCCGTATGCTACAGTGGAGGAGGAGCTGATTGGAGAATTTGTGAAGTATTCCATCA GGGATGGGAAAGAAATAAACTTCTTGAGAAGAGAATCAGAAGCTGGTCAGAAATGTTGCACCTTCCAGCACTGGGTGTACCAGAAAACAA GTGGCTGCCTCCTGGTGACGGACATGCAAGGTGTAGGAATGAAGCTAACTGACGTTGGCATAGCAACGCTGGCTAAAGGGTACAAGGGAT TTAAAGGCAACTGTTCCATGACCTTCATTGATCAGTTTAAAGCACTACACCAGTGTAACAAGTATTGCAAAATGCTGGGACTGAAATCCC TTCAAAACAACAACCAGAAACAGAAGCAGCCGAGCATTGGGAAAAGCAAAGTTCAAACAAACTCTATGACAATAAAGAAGGCAGGGCCTG AGACCCCAGGCGAAAAGAAAACCTAACGTCCCTGGGTAACCTAATGGCCACTGGCTAGCAGCACACAATCTCGCCAGGGAAAATCTGAGG CCACACAGGAGAGAATATACAGCCTGCAGAGAGTGCGTGGCAATCCTTACTCCCAGCCGACTGTGCGCCAAGATGCTTCTAAACCCATCA CCTGCTGTCTTCACTCAAATGATTTCAGAACAGGATTTGCGACCAGGTTTATGGGGAGATTGAATCAACGATTGGTCTCAAAGACAGTCC ATTCTTTATATACATGTTTAGCATTTTTACCAACCTCACATCATGTGTATATTTGTGTATTTGCACATGGTTGTGCTGTCGAGGACCTGG TGCTGAGAAGAGTCTGTTCACAGCCAAAATTCTTCCCACTGTCATTCCTAACCTGGGATTTCTAGACACATCCTGCTGTGATGTAAACAG AAATCACGAATTCGCTCACTGGATCAAGTTGTTCCACTGGTGTCTAATACGCTATTGTTGCCGGAGGTGGGTTCTGTGACGTGAAGCCAT >58409_58409_7_NEDD4L-ALPK2_NEDD4L_chr18_56033460_ENST00000431212_ALPK2_chr18_56191294_ENST00000361673_length(amino acids)=994AA_BP=658 MFFSSFEEKYSDPYVKLSLYVADENRELALVQTKTIKKTLNPKWNEEFYFRVNPSNHRLLFEVFDENRLTRDDFLGQVDVPLSHLPTEDP TMERPYTFKDFLLRPRSHKSRVKGFLRLKMAYMPKNGGQDEENSDQRDDMEHGWEVVDSNDSASQHQEELPPPPLPPGWEEKVDNLGRTY YVNHNNRTTQWHRPSLMDVSSESDNNIRQINQEAAHRRFRSRRHISEDLEPEPSEGGDVPEPWETISEEVNIAGDSLGLALPPPPASPGS RTSPQELSEELSRRLQITPDSNGEQFSSLIQREPSSRLRSCSVTDAVAEQGHLPPPSAPAGRARSSTVTGGEEPTPSVAYVHTTPGLPSG WEERKDAKGRTYYVNHNNRTTTWTRPIMQLAEDGASGSATNSNNHLIEPQIRRPRSLSSPTVTLSAPLEGAKDSPVRRAVKDTLSNPQSP QPSPYNSPKPQHKVTQSFLPPGWEMRIAPNGRPFFIDHNTKTTTWEDPRLKFPVHMRSKTSLNPNDLGPLPPGWEERIHLDGRTFYIDHN SKITQWEDPRLQNPAITGPAVPYSREFKQKYDYFRKKLKKPADIPNRFEMKLHRNNIFEESYRRIMSVKRPDVLKARLWIEFESEKGLDY GGVAREWFFLLSKEMFNPYYGLFEYSATAGDNSTVSFAIVQASPKDQGLYYCCIKNSYGKVTAEFNLTAEVLKQLSSRQDTKGCEEIEFS QLIFKEDFLHDSYFGGRLRGQIATEELHFGEGVHRKAFRSTVMHGLMPVFKPGHACVLKVHNAIAYGTRNNDELIQRNYKLAAQECYVQN TARYYAKIYAAEAQPLEGFGEVPEIIPIFLIHRPENNIPYATVEEELIGEFVKYSIRDGKEINFLRRESEAGQKCCTFQHWVYQKTSGCL LVTDMQGVGMKLTDVGIATLAKGYKGFKGNCSMTFIDQFKALHQCNKYCKMLGLKSLQNNNQKQKQPSIGKSKVQTNSMTIKKAGPETPG -------------------------------------------------------------- >58409_58409_8_NEDD4L-ALPK2_NEDD4L_chr18_56033460_ENST00000435432_ALPK2_chr18_56191294_ENST00000361673_length(transcript)=3858nt_BP=2270nt GCCATTTCCAGAGAGGAACAACCGTGTAGACTGCTTTCCTGGGAGTCAAGTTAAAACTTCTCTCCTGTGACCTTGTCACCCGGCAGTGGA AAGTTACCCTTGGCTGCAGCCACGACTTCCGCATACTCTTCAGAACTTGCTCTGCCCTTGAGTTTTCCAGCTTTCCTTTAATGCACTAAA CCTTTAATATTGTATTCTCCTAAATGAGACGTCTCGCATTTGAGCAGGTAACACTCGGGAGAGTCCCGTATTCTCAGAGTAAAAGTTGTT TCTGGAATTGATCTCGCCAAAAAGGACATCTTTGGAGCCAGCTTCTGCTCCATTGCTGTTGAACTTTTTTTTGGTCGTGACATCAGAAAA ATAACCAAGTGTGAGTCTGATAATAGCAATGATCCGTATGTGAAACTTTCATTGTACGTAGCGGATGAGAATAGAGAACTTGCTTTGGTC CAGACAAAAACAATTAAAAAGACACTGAACCCAAAATGGAATGAAGAATTTTATTTCAGGGTAAACCCATCTAATCACAGACTCCTATTT GAAGTATTTGACGAAAATAGACTGACACGAGACGACTTCCTGGGCCAGGTGGACGTGCCCCTTAGTCACCTTCCGACAGAAGATCCAACC ATGGAGCGACCCTATACATTTAAGGACTTTCTCCTCAGACCAAGAAGTCATAAGTCTCGAGTTAAGGGATTTTTGCGATTGAAAATGGCC TATATGCCAAAAAATGGAGGTCAAGATGAAGAAAACAGTGACCAGAGGGATGACATGGAGCATGGATGGGAAGTTGTTGACTCAAATGAC TCGGCTTCTCAGCACCAAGAGGAACTTCCTCCTCCTCCTCTGCCTCCCGGGTGGGAAGAAAAAGTGGACAATTTAGGCCGAACTTACTAT GTCAACCACAACAACCGGACCACTCAGTGGCACAGACCAAGCCTGATGGACGTGTCCTCGGAGTCGGACAATAACATCAGACAGATCAAC CAGGAGGCAGCACACCGGCGCTTCCGCTCCCGCAGGCACATCAGCGAAGACTTGGAGCCCGAGCCCTCGGAGGGCGGGGATGTCCCCGAG CCTTGGGAGACCATTTCAGAGGAAGTGAATATCGCTGGAGACTCTCTCGGTCTGGCTCTGCCCCCACCACCGGCCTCCCCAGGATCTCGG ACCAGCCCTCAGGAGCTGTCAGAGGAACTAAGCAGAAGGCTTCAGATCACTCCAGACTCCAATGGGGAACAGTTCAGCTCTTTGATTCAA AGAGAACCCTCCTCAAGGTTGAGGTCATGCAGTGTCACCGACGCAGTTGCAGAACAGGGCCATCTACCACCGCCATCAGTGGCCTATGTA CATACCACGCCGGGTCTGCCTTCAGGCTGGGAAGAAAGAAAAGATGCTAAGGGGCGCACATACTATGTCAATCATAACAATCGAACCACA ACTTGGACTCGACCTATCATGCAGCTTGCAGAAGATGGTGCGTCCGGATCAGCCACAAACAGTAACAACCATCTAATCGAGCCTCAGATC CGCCGGCCTCGTAGCCTCAGCTCGCCAACAGTAACTTTATCTGCCCCGCTGGAGGGTGCCAAGGACTCACCCGTACGTCGGGCTGTGAAA GACACCCTTTCCAACCCACAGTCCCCACAGCCATCACCTTACAACTCCCCCAAACCACAACACAAAGTCACACAGAGCTTCTTGCCACCC GGCTGGGAAATGAGGATAGCGCCAAACGGCCGGCCCTTCTTCATTGATCATAACACAAAGACTACAACCTGGGAAGATCCACGTTTGAAA TTTCCAGTACATATGCGGTCAAAGACATCTTTAAACCCCAATGACCTTGGCCCCCTTCCTCCTGGCTGGGAAGAAAGAATTCACTTGGAT GGCCGAACGTTTTATATTGATCATAATAGCAAAATTACTCAGTGGGAAGACCCAAGACTGCAGAACCCAGCTATTACTGGTCCGGCTGTC CCTTACTCCAGAGAATTTAAGCAGAAATATGACTACTTCAGGAAGAAATTAAAGAAACCTGCTGATATCCCCAATAGGTTTGAAATGAAA CTTCACAGAAATAACATATTTGAAGAGTCCTATCGGAGAATTATGTCCGTGAAAAGACCAGATGTCCTAAAAGCTAGACTGTGGATTGAG TTTGAATCAGAGAAAGGTCTTGACTATGGGGGTGTGGCCAGAGAATGGTTCTTCTTACTGTCCAAAGAGATGTTCAACCCCTACTACGGC CTCTTTGAGTACTCTGCCACTGCAGGGGACAACTCCACTGTTTCCTTTGCCATCGTGCAAGCCAGTCCGAAGGACCAGGGACTCTATTAC TGCTGCATCAAGAACAGCTACGGAAAAGTGACTGCTGAATTTAACCTCACAGCTGAAGTTCTCAAACAGCTGTCAAGTCGCCAGGATACT AAAGGATGTGAAGAGATTGAATTCAGCCAACTCATCTTCAAAGAAGACTTCCTCCATGACAGCTACTTTGGGGGCCGCCTGCGTGGTCAG ATCGCCACGGAGGAGCTGCACTTTGGAGAAGGGGTTCACCGCAAAGCCTTCCGCAGCACAGTGATGCACGGCCTCATGCCTGTCTTCAAA CCTGGCCATGCCTGTGTGCTTAAGGTGCACAATGCCATTGCCTATGGGACCAGAAATAATGATGAGCTCATCCAAAGGAACTACAAACTC GCTGCCCAGGAATGCTATGTTCAAAATACTGCCAGGTATTATGCCAAGATCTACGCTGCTGAAGCACAGCCTCTGGAAGGCTTTGGAGAA GTACCTGAGATCATTCCTATTTTTCTTATCCATCGGCCTGAGAACAATATCCCGTATGCTACAGTGGAGGAGGAGCTGATTGGAGAATTT GTGAAGTATTCCATCAGGGATGGGAAAGAAATAAACTTCTTGAGAAGAGAATCAGAAGCTGGTCAGAAATGTTGCACCTTCCAGCACTGG GTGTACCAGAAAACAAGTGGCTGCCTCCTGGTGACGGACATGCAAGGTGTAGGAATGAAGCTAACTGACGTTGGCATAGCAACGCTGGCT AAAGGGTACAAGGGATTTAAAGGCAACTGTTCCATGACCTTCATTGATCAGTTTAAAGCACTACACCAGTGTAACAAGTATTGCAAAATG CTGGGACTGAAATCCCTTCAAAACAACAACCAGAAACAGAAGCAGCCGAGCATTGGGAAAAGCAAAGTTCAAACAAACTCTATGACAATA AAGAAGGCAGGGCCTGAGACCCCAGGCGAAAAGAAAACCTAACGTCCCTGGGTAACCTAATGGCCACTGGCTAGCAGCACACAATCTCGC CAGGGAAAATCTGAGGCCACACAGGAGAGAATATACAGCCTGCAGAGAGTGCGTGGCAATCCTTACTCCCAGCCGACTGTGCGCCAAGAT GCTTCTAAACCCATCACCTGCTGTCTTCACTCAAATGATTTCAGAACAGGATTTGCGACCAGGTTTATGGGGAGATTGAATCAACGATTG GTCTCAAAGACAGTCCATTCTTTATATACATGTTTAGCATTTTTACCAACCTCACATCATGTGTATATTTGTGTATTTGCACATGGTTGT GCTGTCGAGGACCTGGTGCTGAGAAGAGTCTGTTCACAGCCAAAATTCTTCCCACTGTCATTCCTAACCTGGGATTTCTAGACACATCCT GCTGTGATGTAAACAGAAATCACGAATTCGCTCACTGGATCAAGTTGTTCCACTGGTGTCTAATACGCTATTGTTGCCGGAGGTGGGTTC >58409_58409_8_NEDD4L-ALPK2_NEDD4L_chr18_56033460_ENST00000435432_ALPK2_chr18_56191294_ENST00000361673_length(amino acids)=956AA_BP=620 MYVADENRELALVQTKTIKKTLNPKWNEEFYFRVNPSNHRLLFEVFDENRLTRDDFLGQVDVPLSHLPTEDPTMERPYTFKDFLLRPRSH KSRVKGFLRLKMAYMPKNGGQDEENSDQRDDMEHGWEVVDSNDSASQHQEELPPPPLPPGWEEKVDNLGRTYYVNHNNRTTQWHRPSLMD VSSESDNNIRQINQEAAHRRFRSRRHISEDLEPEPSEGGDVPEPWETISEEVNIAGDSLGLALPPPPASPGSRTSPQELSEELSRRLQIT PDSNGEQFSSLIQREPSSRLRSCSVTDAVAEQGHLPPPSVAYVHTTPGLPSGWEERKDAKGRTYYVNHNNRTTTWTRPIMQLAEDGASGS ATNSNNHLIEPQIRRPRSLSSPTVTLSAPLEGAKDSPVRRAVKDTLSNPQSPQPSPYNSPKPQHKVTQSFLPPGWEMRIAPNGRPFFIDH NTKTTTWEDPRLKFPVHMRSKTSLNPNDLGPLPPGWEERIHLDGRTFYIDHNSKITQWEDPRLQNPAITGPAVPYSREFKQKYDYFRKKL KKPADIPNRFEMKLHRNNIFEESYRRIMSVKRPDVLKARLWIEFESEKGLDYGGVAREWFFLLSKEMFNPYYGLFEYSATAGDNSTVSFA IVQASPKDQGLYYCCIKNSYGKVTAEFNLTAEVLKQLSSRQDTKGCEEIEFSQLIFKEDFLHDSYFGGRLRGQIATEELHFGEGVHRKAF RSTVMHGLMPVFKPGHACVLKVHNAIAYGTRNNDELIQRNYKLAAQECYVQNTARYYAKIYAAEAQPLEGFGEVPEIIPIFLIHRPENNI PYATVEEELIGEFVKYSIRDGKEINFLRRESEAGQKCCTFQHWVYQKTSGCLLVTDMQGVGMKLTDVGIATLAKGYKGFKGNCSMTFIDQ -------------------------------------------------------------- >58409_58409_9_NEDD4L-ALPK2_NEDD4L_chr18_56033460_ENST00000456173_ALPK2_chr18_56191294_ENST00000361673_length(transcript)=3813nt_BP=2225nt ACTTCCGTGTTCCCCACATTTGAATTTGCTCCCGATTCGAGAGAGGCAGGCATCCGCGGCAGCAGCTTCCAACCCAGACAGGCTTAAGCC GCGCGAGGGTGCCCGGGTGGGTGGCTGCGCAGGGCCCTACCTGGGCGGGAGCGGCTGCAGAGCCCTGTCCACGCGGTGCCTCCCCAGCAC GGCACCTCCCACTCCAGGCTGTTGGTTACCTGGCCGGGAGCTGGCGGAGACCAGGATTTCTCCTCGCCGCCGTTGCTGTTGTTAGGGGAA ACAGACCATCTGCATCTAGACCTGCCTCTCTCTCCGCTCCCCACTTCAGACGAGCTCTTCCTGCCTGGAATCTGTGATCCGTATGTGAAA CTTTCATTGTACGTAGCGGATGAGAATAGAGAACTTGCTTTGGTCCAGACAAAAACAATTAAAAAGACACTGAACCCAAAATGGAATGAA GAATTTTATTTCAGGGTAAACCCATCTAATCACAGACTCCTATTTGAAGTATTTGACGAAAATAGACTGACACGAGACGACTTCCTGGGC CAGGTGGACGTGCCCCTTAGTCACCTTCCGACAGAAGATCCAACCATGGAGCGACCCTATACATTTAAGGACTTTCTCCTCAGACCAAGA AGTCATAAGTCTCGAGTTAAGGGATTTTTGCGATTGAAAATGGCCTATATGCCAAAAAATGGAGGTCAAGATGAAGAAAACAGTGACCAG AGGGATGACATGGAGCATGGATGGGAAGTTGTTGACTCAAATGACTCGGCTTCTCAGCACCAAGAGGAACTTCCTCCTCCTCCTCTGCCT CCCGGGTGGGAAGAAAAAGTGGACAATTTAGGCCGAACTTACTATGTCAACCACAACAACCGGACCACTCAGTGGCACAGACCAAGCCTG ATGGACGTGTCCTCGGAGTCGGACAATAACATCAGACAGATCAACCAGGAGGCAGCACACCGGCGCTTCCGCTCCCGCAGGCACATCAGC GAAGACTTGGAGCCCGAGCCCTCGGAGGGCGGGGATGTCCCCGAGCCTTGGGAGACCATTTCAGAGGAAGTGAATATCGCTGGAGACTCT CTCGGTCTGGCTCTGCCCCCACCACCGGCCTCCCCAGGATCTCGGACCAGCCCTCAGGAGCTGTCAGAGGAACTAAGCAGAAGGCTTCAG ATCACTCCAGACTCCAATGGGGAACAGTTCAGCTCTTTGATTCAAAGAGAACCCTCCTCAAGGTTGAGGTCATGCAGTGTCACCGACGCA GTTGCAGAACAGGGCCATCTACCACCGCCATCAGTGGCCTATGTACATACCACGCCGGGTCTGCCTTCAGGCTGGGAAGAAAGAAAAGAT GCTAAGGGGCGCACATACTATGTCAATCATAACAATCGAACCACAACTTGGACTCGACCTATCATGCAGCTTGCAGAAGATGGTGCGTCC GGATCAGCCACAAACAGTAACAACCATCTAATCGAGCCTCAGATCCGCCGGCCTCGTAGCCTCAGCTCGCCAACAGTAACTTTATCTGCC CCGCTGGAGGGTGCCAAGGACTCACCCGTACGTCGGGCTGTGAAAGACACCCTTTCCAACCCACAGTCCCCACAGCCATCACCTTACAAC TCCCCCAAACCACAACACAAAGTCACACAGAGCTTCTTGCCACCCGGCTGGGAAATGAGGATAGCGCCAAACGGCCGGCCCTTCTTCATT GATCATAACACAAAGACTACAACCTGGGAAGATCCACGTTTGAAATTTCCAGTACATATGCGGTCAAAGACATCTTTAAACCCCAATGAC CTTGGCCCCCTTCCTCCTGGCTGGGAAGAAAGAATTCACTTGGATGGCCGAACGTTTTATATTGATCATAATAGCAAAATTACTCAGTGG GAAGACCCAAGACTGCAGAACCCAGCTATTACTGGTCCGGCTGTCCCTTACTCCAGAGAATTTAAGCAGAAATATGACTACTTCAGGAAG AAATTAAAGAAACCTGCTGATATCCCCAATAGGTTTGAAATGAAACTTCACAGAAATAACATATTTGAAGAGTCCTATCGGAGAATTATG TCCGTGAAAAGACCAGATGTCCTAAAAGCTAGACTGTGGATTGAGTTTGAATCAGAGAAAGGTCTTGACTATGGGGGTGTGGCCAGAGAA TGGTTCTTCTTACTGTCCAAAGAGATGTTCAACCCCTACTACGGCCTCTTTGAGTACTCTGCCACTGCAGGGGACAACTCCACTGTTTCC TTTGCCATCGTGCAAGCCAGTCCGAAGGACCAGGGACTCTATTACTGCTGCATCAAGAACAGCTACGGAAAAGTGACTGCTGAATTTAAC CTCACAGCTGAAGTTCTCAAACAGCTGTCAAGTCGCCAGGATACTAAAGGATGTGAAGAGATTGAATTCAGCCAACTCATCTTCAAAGAA GACTTCCTCCATGACAGCTACTTTGGGGGCCGCCTGCGTGGTCAGATCGCCACGGAGGAGCTGCACTTTGGAGAAGGGGTTCACCGCAAA GCCTTCCGCAGCACAGTGATGCACGGCCTCATGCCTGTCTTCAAACCTGGCCATGCCTGTGTGCTTAAGGTGCACAATGCCATTGCCTAT GGGACCAGAAATAATGATGAGCTCATCCAAAGGAACTACAAACTCGCTGCCCAGGAATGCTATGTTCAAAATACTGCCAGGTATTATGCC AAGATCTACGCTGCTGAAGCACAGCCTCTGGAAGGCTTTGGAGAAGTACCTGAGATCATTCCTATTTTTCTTATCCATCGGCCTGAGAAC AATATCCCGTATGCTACAGTGGAGGAGGAGCTGATTGGAGAATTTGTGAAGTATTCCATCAGGGATGGGAAAGAAATAAACTTCTTGAGA AGAGAATCAGAAGCTGGTCAGAAATGTTGCACCTTCCAGCACTGGGTGTACCAGAAAACAAGTGGCTGCCTCCTGGTGACGGACATGCAA GGTGTAGGAATGAAGCTAACTGACGTTGGCATAGCAACGCTGGCTAAAGGGTACAAGGGATTTAAAGGCAACTGTTCCATGACCTTCATT GATCAGTTTAAAGCACTACACCAGTGTAACAAGTATTGCAAAATGCTGGGACTGAAATCCCTTCAAAACAACAACCAGAAACAGAAGCAG CCGAGCATTGGGAAAAGCAAAGTTCAAACAAACTCTATGACAATAAAGAAGGCAGGGCCTGAGACCCCAGGCGAAAAGAAAACCTAACGT CCCTGGGTAACCTAATGGCCACTGGCTAGCAGCACACAATCTCGCCAGGGAAAATCTGAGGCCACACAGGAGAGAATATACAGCCTGCAG AGAGTGCGTGGCAATCCTTACTCCCAGCCGACTGTGCGCCAAGATGCTTCTAAACCCATCACCTGCTGTCTTCACTCAAATGATTTCAGA ACAGGATTTGCGACCAGGTTTATGGGGAGATTGAATCAACGATTGGTCTCAAAGACAGTCCATTCTTTATATACATGTTTAGCATTTTTA CCAACCTCACATCATGTGTATATTTGTGTATTTGCACATGGTTGTGCTGTCGAGGACCTGGTGCTGAGAAGAGTCTGTTCACAGCCAAAA TTCTTCCCACTGTCATTCCTAACCTGGGATTTCTAGACACATCCTGCTGTGATGTAAACAGAAATCACGAATTCGCTCACTGGATCAAGT TGTTCCACTGGTGTCTAATACGCTATTGTTGCCGGAGGTGGGTTCTGTGACGTGAAGCCATTTCCCATCATTCAACAGCCAGTTACAATT >58409_58409_9_NEDD4L-ALPK2_NEDD4L_chr18_56033460_ENST00000456173_ALPK2_chr18_56191294_ENST00000361673_length(amino acids)=1040AA_BP=704 MRRALPGRERLQSPVHAVPPQHGTSHSRLLVTWPGAGGDQDFSSPPLLLLGETDHLHLDLPLSPLPTSDELFLPGICDPYVKLSLYVADE NRELALVQTKTIKKTLNPKWNEEFYFRVNPSNHRLLFEVFDENRLTRDDFLGQVDVPLSHLPTEDPTMERPYTFKDFLLRPRSHKSRVKG FLRLKMAYMPKNGGQDEENSDQRDDMEHGWEVVDSNDSASQHQEELPPPPLPPGWEEKVDNLGRTYYVNHNNRTTQWHRPSLMDVSSESD NNIRQINQEAAHRRFRSRRHISEDLEPEPSEGGDVPEPWETISEEVNIAGDSLGLALPPPPASPGSRTSPQELSEELSRRLQITPDSNGE QFSSLIQREPSSRLRSCSVTDAVAEQGHLPPPSVAYVHTTPGLPSGWEERKDAKGRTYYVNHNNRTTTWTRPIMQLAEDGASGSATNSNN HLIEPQIRRPRSLSSPTVTLSAPLEGAKDSPVRRAVKDTLSNPQSPQPSPYNSPKPQHKVTQSFLPPGWEMRIAPNGRPFFIDHNTKTTT WEDPRLKFPVHMRSKTSLNPNDLGPLPPGWEERIHLDGRTFYIDHNSKITQWEDPRLQNPAITGPAVPYSREFKQKYDYFRKKLKKPADI PNRFEMKLHRNNIFEESYRRIMSVKRPDVLKARLWIEFESEKGLDYGGVAREWFFLLSKEMFNPYYGLFEYSATAGDNSTVSFAIVQASP KDQGLYYCCIKNSYGKVTAEFNLTAEVLKQLSSRQDTKGCEEIEFSQLIFKEDFLHDSYFGGRLRGQIATEELHFGEGVHRKAFRSTVMH GLMPVFKPGHACVLKVHNAIAYGTRNNDELIQRNYKLAAQECYVQNTARYYAKIYAAEAQPLEGFGEVPEIIPIFLIHRPENNIPYATVE EELIGEFVKYSIRDGKEINFLRRESEAGQKCCTFQHWVYQKTSGCLLVTDMQGVGMKLTDVGIATLAKGYKGFKGNCSMTFIDQFKALHQ -------------------------------------------------------------- >58409_58409_10_NEDD4L-ALPK2_NEDD4L_chr18_56033460_ENST00000456986_ALPK2_chr18_56191294_ENST00000361673_length(transcript)=3888nt_BP=2300nt ATTTTGACCGCTATTTAGAAGAGTGACCTCATAAATCTTTTAGCAAAGTAGACACACATACCTACCACATTTCTTAAAAGTAGATTCGTA TTTTGATTTGAGATTGTTGAAAAGCATGGTATGTTTGGAGTGCACTTAGTTATGTCCCATCTCATAAAGACTGTTGAGCTCTCTGCACTG CTGATGATGAAGCATTGCATGAACCCAGAAAACGGGGATGCCAAAGCACAGGGCTTAGGTGCTGTTCCTTGCGTCATCAGCAGAGGTCTG TCCACTTTGTAGAAGGGAGAGTCCCGTATTCTCAGAGTAAAAGTTGTTTCTGGAATTGATCTCGCCAAAAAGGACATCTTTGGAGCCAGT GATCCGTATGTGAAACTTTCATTGTACGTAGCGGATGAGAATAGAGAACTTGCTTTGGTCCAGACAAAAACAATTAAAAAGACACTGAAC CCAAAATGGAATGAAGAATTTTATTTCAGGGTAAACCCATCTAATCACAGACTCCTATTTGAAGTATTTGACGAAAATAGACTGACACGA GACGACTTCCTGGGCCAGGTGGACGTGCCCCTTAGTCACCTTCCGACAGAAGATCCAACCATGGAGCGACCCTATACATTTAAGGACTTT CTCCTCAGACCAAGAAGTCATAAGTCTCGAGTTAAGGGATTTTTGCGATTGAAAATGGCCTATATGCCAAAAAATGGAGGTCAAGATGAA GAAAACAGTGACCAGAGGGATGACATGGAGCATGGATGGGAAGTTGTTGACTCAAATGACTCGGCTTCTCAGCACCAAGAGGAACTTCCT CCTCCTCCTCTGCCTCCCGGGTGGGAAGAAAAAGTGGACAATTTAGGCCGAACTTACTATGTCAACCACAACAACCGGACCACTCAGTGG CACAGACCAAGCCTGATGGACGTGTCCTCGGAGTCGGACAATAACATCAGACAGATCAACCAGGAGGCAGCACACCGGCGCTTCCGCTCC CGCAGGCACATCAGCGAAGACTTGGAGCCCGAGCCCTCGGAGGGCGGGGATGTCCCCGAGCCTTGGGAGACCATTTCAGAGGAAGTGAAT ATCGCTGGAGACTCTCTCGGTCTGGCTCTGCCCCCACCACCGGCCTCCCCAGGATCTCGGACCAGCCCTCAGGAGCTGTCAGAGGAACTA AGCAGAAGGCTTCAGATCACTCCAGACTCCAATGGGGAACAGTTCAGCTCTTTGATTCAAAGAGAACCCTCCTCAAGGTTGAGGTCATGC AGTGTCACCGACGCAGTTGCAGAACAGGGCCATCTACCACCGCCCAGTGCCCCAGCTGGGAGAGCGCGTTCATCAACTGTCACGGGTGGT GAGGAACCAACGCCATCAGTGGCCTATGTACATACCACGCCGGGTCTGCCTTCAGGCTGGGAAGAAAGAAAAGATGCTAAGGGGCGCACA TACTATGTCAATCATAACAATCGAACCACAACTTGGACTCGACCTATCATGCAGCTTGCAGAAGATGGTGCGTCCGGATCAGCCACAAAC AGTAACAACCATCTAATCGAGCCTCAGATCCGCCGGCCTCGTAGCCTCAGCTCGCCAACAGTAACTTTATCTGCCCCGCTGGAGGGTGCC AAGGACTCACCCGTACGTCGGGCTGTGAAAGACACCCTTTCCAACCCACAGTCCCCACAGCCATCACCTTACAACTCCCCCAAACCACAA CACAAAGTCACACAGAGCTTCTTGCCACCCGGCTGGGAAATGAGGATAGCGCCAAACGGCCGGCCCTTCTTCATTGATCATAACACAAAG ACTACAACCTGGGAAGATCCACGTTTGAAATTTCCAGTACATATGCGGTCAAAGACATCTTTAAACCCCAATGACCTTGGCCCCCTTCCT CCTGGCTGGGAAGAAAGAATTCACTTGGATGGCCGAACGTTTTATATTGATCATAATAGCAAAATTACTCAGTGGGAAGACCCAAGACTG CAGAACCCAGCTATTACTGGTCCGGCTGTCCCTTACTCCAGAGAATTTAAGCAGAAATATGACTACTTCAGGAAGAAATTAAAGAAACCT GCTGATATCCCCAATAGGTTTGAAATGAAACTTCACAGAAATAACATATTTGAAGAGTCCTATCGGAGAATTATGTCCGTGAAAAGACCA GATGTCCTAAAAGCTAGACTGTGGATTGAGTTTGAATCAGAGAAAGGTCTTGACTATGGGGGTGTGGCCAGAGAATGGTTCTTCTTACTG TCCAAAGAGATGTTCAACCCCTACTACGGCCTCTTTGAGTACTCTGCCACTGCAGGGGACAACTCCACTGTTTCCTTTGCCATCGTGCAA GCCAGTCCGAAGGACCAGGGACTCTATTACTGCTGCATCAAGAACAGCTACGGAAAAGTGACTGCTGAATTTAACCTCACAGCTGAAGTT CTCAAACAGCTGTCAAGTCGCCAGGATACTAAAGGATGTGAAGAGATTGAATTCAGCCAACTCATCTTCAAAGAAGACTTCCTCCATGAC AGCTACTTTGGGGGCCGCCTGCGTGGTCAGATCGCCACGGAGGAGCTGCACTTTGGAGAAGGGGTTCACCGCAAAGCCTTCCGCAGCACA GTGATGCACGGCCTCATGCCTGTCTTCAAACCTGGCCATGCCTGTGTGCTTAAGGTGCACAATGCCATTGCCTATGGGACCAGAAATAAT GATGAGCTCATCCAAAGGAACTACAAACTCGCTGCCCAGGAATGCTATGTTCAAAATACTGCCAGGTATTATGCCAAGATCTACGCTGCT GAAGCACAGCCTCTGGAAGGCTTTGGAGAAGTACCTGAGATCATTCCTATTTTTCTTATCCATCGGCCTGAGAACAATATCCCGTATGCT ACAGTGGAGGAGGAGCTGATTGGAGAATTTGTGAAGTATTCCATCAGGGATGGGAAAGAAATAAACTTCTTGAGAAGAGAATCAGAAGCT GGTCAGAAATGTTGCACCTTCCAGCACTGGGTGTACCAGAAAACAAGTGGCTGCCTCCTGGTGACGGACATGCAAGGTGTAGGAATGAAG CTAACTGACGTTGGCATAGCAACGCTGGCTAAAGGGTACAAGGGATTTAAAGGCAACTGTTCCATGACCTTCATTGATCAGTTTAAAGCA CTACACCAGTGTAACAAGTATTGCAAAATGCTGGGACTGAAATCCCTTCAAAACAACAACCAGAAACAGAAGCAGCCGAGCATTGGGAAA AGCAAAGTTCAAACAAACTCTATGACAATAAAGAAGGCAGGGCCTGAGACCCCAGGCGAAAAGAAAACCTAACGTCCCTGGGTAACCTAA TGGCCACTGGCTAGCAGCACACAATCTCGCCAGGGAAAATCTGAGGCCACACAGGAGAGAATATACAGCCTGCAGAGAGTGCGTGGCAAT CCTTACTCCCAGCCGACTGTGCGCCAAGATGCTTCTAAACCCATCACCTGCTGTCTTCACTCAAATGATTTCAGAACAGGATTTGCGACC AGGTTTATGGGGAGATTGAATCAACGATTGGTCTCAAAGACAGTCCATTCTTTATATACATGTTTAGCATTTTTACCAACCTCACATCAT GTGTATATTTGTGTATTTGCACATGGTTGTGCTGTCGAGGACCTGGTGCTGAGAAGAGTCTGTTCACAGCCAAAATTCTTCCCACTGTCA TTCCTAACCTGGGATTTCTAGACACATCCTGCTGTGATGTAAACAGAAATCACGAATTCGCTCACTGGATCAAGTTGTTCCACTGGTGTC TAATACGCTATTGTTGCCGGAGGTGGGTTCTGTGACGTGAAGCCATTTCCCATCATTCAACAGCCAGTTACAATTTTCTGTTTAATTAAA >58409_58409_10_NEDD4L-ALPK2_NEDD4L_chr18_56033460_ENST00000456986_ALPK2_chr18_56191294_ENST00000361673_length(amino acids)=976AA_BP=640 MYVADENRELALVQTKTIKKTLNPKWNEEFYFRVNPSNHRLLFEVFDENRLTRDDFLGQVDVPLSHLPTEDPTMERPYTFKDFLLRPRSH KSRVKGFLRLKMAYMPKNGGQDEENSDQRDDMEHGWEVVDSNDSASQHQEELPPPPLPPGWEEKVDNLGRTYYVNHNNRTTQWHRPSLMD VSSESDNNIRQINQEAAHRRFRSRRHISEDLEPEPSEGGDVPEPWETISEEVNIAGDSLGLALPPPPASPGSRTSPQELSEELSRRLQIT PDSNGEQFSSLIQREPSSRLRSCSVTDAVAEQGHLPPPSAPAGRARSSTVTGGEEPTPSVAYVHTTPGLPSGWEERKDAKGRTYYVNHNN RTTTWTRPIMQLAEDGASGSATNSNNHLIEPQIRRPRSLSSPTVTLSAPLEGAKDSPVRRAVKDTLSNPQSPQPSPYNSPKPQHKVTQSF LPPGWEMRIAPNGRPFFIDHNTKTTTWEDPRLKFPVHMRSKTSLNPNDLGPLPPGWEERIHLDGRTFYIDHNSKITQWEDPRLQNPAITG PAVPYSREFKQKYDYFRKKLKKPADIPNRFEMKLHRNNIFEESYRRIMSVKRPDVLKARLWIEFESEKGLDYGGVAREWFFLLSKEMFNP YYGLFEYSATAGDNSTVSFAIVQASPKDQGLYYCCIKNSYGKVTAEFNLTAEVLKQLSSRQDTKGCEEIEFSQLIFKEDFLHDSYFGGRL RGQIATEELHFGEGVHRKAFRSTVMHGLMPVFKPGHACVLKVHNAIAYGTRNNDELIQRNYKLAAQECYVQNTARYYAKIYAAEAQPLEG FGEVPEIIPIFLIHRPENNIPYATVEEELIGEFVKYSIRDGKEINFLRRESEAGQKCCTFQHWVYQKTSGCLLVTDMQGVGMKLTDVGIA -------------------------------------------------------------- >58409_58409_11_NEDD4L-ALPK2_NEDD4L_chr18_56033460_ENST00000586263_ALPK2_chr18_56191294_ENST00000361673_length(transcript)=3766nt_BP=2178nt TTTCCAGAGAGGAACAACCGTGTAGACTGCTTTCCTGGGAGTCAAGTTAAAACTTCTCTCCTGTGACCTTGTCACCCGGCAGTGGAAAGT TACCCTTGGCTGCAGCCACGACTTCCGCATACTCTTCAGAACTTGCTCTGCCCTTGAGTTTTCCAGCTTTCCTTTAATGCACTAAACCTT TAATATTGTATTCTCCTAAATGAGACGTCTCGCATTTGAGCAGGGAGAGTCCCGTATTCTCAGAGTAAAAGTTGTTTCTGGAATTGATCT CGCCAAAAAGGACATCTTTGGAGCCAGTGATCCGTATGTGAAACTTTCATTGTACGTAGCGGATGAGAATAGAGAACTTGCTTTGGTCCA GACAAAAACAATTAAAAAGACACTGAACCCAAAATGGAATGAAGAATTTTATTTCAGGGTAAACCCATCTAATCACAGACTCCTATTTGA AGTATTTGACGAAAATAGACTGACACGAGACGACTTCCTGGGCCAGGTGGACGTGCCCCTTAGTCACCTTCCGACAGAAGATCCAACCAT GGAGCGACCCTATACATTTAAGGACTTTCTCCTCAGACCAAGAAGTCATAAGTCTCGAGTTAAGGGATTTTTGCGATTGAAAATGGCCTA TATGCCAAAAAATGGAGGTCAAGATGAAGAAAACAGTGACCAGAGGGATGACATGGAGCATGGATGGGAAGTTGTTGACTCAAATGACTC GGCTTCTCAGCACCAAGAGGAACTTCCTCCTCCTCCTCTGCCTCCCGGGTGGGAAGAAAAAGTGGACAATTTAGGCCGAACTTACTATGT CAACCACAACAACCGGACCACTCAGTGGCACAGACCAAGCCTGATGGACGTGTCCTCGGAGTCGGACAATAACATCAGACAGATCAACCA GGAGGCAGCACACCGGCGCTTCCGCTCCCGCAGGCACATCAGCGAAGACTTGGAGCCCGAGCCCTCGGAGGGCGGGGATGTCCCCGAGCC TTGGGAGACCATTTCAGAGGAAGTGAATATCGCTGGAGACTCTCTCGGTCTGGCTCTGCCCCCACCACCGGCCTCCCCAGGATCTCGGAC CAGCCCTCAGGAGCTGTCAGAGGAACTAAGCAGAAGGCTTCAGATCACTCCAGACTCCAATGGGGAACAGTTCAGCTCTTTGATTCAAAG AGAACCCTCCTCAAGGTTGAGGTCATGCAGTGTCACCGACGCAGTTGCAGAACAGGGCCATCTACCACCGCCATCAGTGGCCTATGTACA TACCACGCCGGGTCTGCCTTCAGGCTGGGAAGAAAGAAAAGATGCTAAGGGGCGCACATACTATGTCAATCATAACAATCGAACCACAAC TTGGACTCGACCTATCATGCAGCTTGCAGAAGATGGTGCGTCCGGATCAGCCACAAACAGTAACAACCATCTAATCGAGCCTCAGATCCG CCGGCCTCGTAGCCTCAGCTCGCCAACAGTAACTTTATCTGCCCCGCTGGAGGGTGCCAAGGACTCACCCGTACGTCGGGCTGTGAAAGA CACCCTTTCCAACCCACAGTCCCCACAGCCATCACCTTACAACTCCCCCAAACCACAACACAAAGTCACACAGAGCTTCTTGCCACCCGG CTGGGAAATGAGGATAGCGCCAAACGGCCGGCCCTTCTTCATTGATCATAACACAAAGACTACAACCTGGGAAGATCCACGTTTGAAATT TCCAGTACATATGCGGTCAAAGACATCTTTAAACCCCAATGACCTTGGCCCCCTTCCTCCTGGCTGGGAAGAAAGAATTCACTTGGATGG CCGAACGTTTTATATTGATCATAATAGCAAAATTACTCAGTGGGAAGACCCAAGACTGCAGAACCCAGCTATTACTGGTCCGGCTGTCCC TTACTCCAGAGAATTTAAGCAGAAATATGACTACTTCAGGAAGAAATTAAAGAAACCTGCTGATATCCCCAATAGGTTTGAAATGAAACT TCACAGAAATAACATATTTGAAGAGTCCTATCGGAGAATTATGTCCGTGAAAAGACCAGATGTCCTAAAAGCTAGACTGTGGATTGAGTT TGAATCAGAGAAAGGTCTTGACTATGGGGGTGTGGCCAGAGAATGGTTCTTCTTACTGTCCAAAGAGATGTTCAACCCCTACTACGGCCT CTTTGAGTACTCTGCCACTGCAGGGGACAACTCCACTGTTTCCTTTGCCATCGTGCAAGCCAGTCCGAAGGACCAGGGACTCTATTACTG CTGCATCAAGAACAGCTACGGAAAAGTGACTGCTGAATTTAACCTCACAGCTGAAGTTCTCAAACAGCTGTCAAGTCGCCAGGATACTAA AGGATGTGAAGAGATTGAATTCAGCCAACTCATCTTCAAAGAAGACTTCCTCCATGACAGCTACTTTGGGGGCCGCCTGCGTGGTCAGAT CGCCACGGAGGAGCTGCACTTTGGAGAAGGGGTTCACCGCAAAGCCTTCCGCAGCACAGTGATGCACGGCCTCATGCCTGTCTTCAAACC TGGCCATGCCTGTGTGCTTAAGGTGCACAATGCCATTGCCTATGGGACCAGAAATAATGATGAGCTCATCCAAAGGAACTACAAACTCGC TGCCCAGGAATGCTATGTTCAAAATACTGCCAGGTATTATGCCAAGATCTACGCTGCTGAAGCACAGCCTCTGGAAGGCTTTGGAGAAGT ACCTGAGATCATTCCTATTTTTCTTATCCATCGGCCTGAGAACAATATCCCGTATGCTACAGTGGAGGAGGAGCTGATTGGAGAATTTGT GAAGTATTCCATCAGGGATGGGAAAGAAATAAACTTCTTGAGAAGAGAATCAGAAGCTGGTCAGAAATGTTGCACCTTCCAGCACTGGGT GTACCAGAAAACAAGTGGCTGCCTCCTGGTGACGGACATGCAAGGTGTAGGAATGAAGCTAACTGACGTTGGCATAGCAACGCTGGCTAA AGGGTACAAGGGATTTAAAGGCAACTGTTCCATGACCTTCATTGATCAGTTTAAAGCACTACACCAGTGTAACAAGTATTGCAAAATGCT GGGACTGAAATCCCTTCAAAACAACAACCAGAAACAGAAGCAGCCGAGCATTGGGAAAAGCAAAGTTCAAACAAACTCTATGACAATAAA GAAGGCAGGGCCTGAGACCCCAGGCGAAAAGAAAACCTAACGTCCCTGGGTAACCTAATGGCCACTGGCTAGCAGCACACAATCTCGCCA GGGAAAATCTGAGGCCACACAGGAGAGAATATACAGCCTGCAGAGAGTGCGTGGCAATCCTTACTCCCAGCCGACTGTGCGCCAAGATGC TTCTAAACCCATCACCTGCTGTCTTCACTCAAATGATTTCAGAACAGGATTTGCGACCAGGTTTATGGGGAGATTGAATCAACGATTGGT CTCAAAGACAGTCCATTCTTTATATACATGTTTAGCATTTTTACCAACCTCACATCATGTGTATATTTGTGTATTTGCACATGGTTGTGC TGTCGAGGACCTGGTGCTGAGAAGAGTCTGTTCACAGCCAAAATTCTTCCCACTGTCATTCCTAACCTGGGATTTCTAGACACATCCTGC TGTGATGTAAACAGAAATCACGAATTCGCTCACTGGATCAAGTTGTTCCACTGGTGTCTAATACGCTATTGTTGCCGGAGGTGGGTTCTG >58409_58409_11_NEDD4L-ALPK2_NEDD4L_chr18_56033460_ENST00000586263_ALPK2_chr18_56191294_ENST00000361673_length(amino acids)=996AA_BP=660 MRRLAFEQGESRILRVKVVSGIDLAKKDIFGASDPYVKLSLYVADENRELALVQTKTIKKTLNPKWNEEFYFRVNPSNHRLLFEVFDENR LTRDDFLGQVDVPLSHLPTEDPTMERPYTFKDFLLRPRSHKSRVKGFLRLKMAYMPKNGGQDEENSDQRDDMEHGWEVVDSNDSASQHQE ELPPPPLPPGWEEKVDNLGRTYYVNHNNRTTQWHRPSLMDVSSESDNNIRQINQEAAHRRFRSRRHISEDLEPEPSEGGDVPEPWETISE EVNIAGDSLGLALPPPPASPGSRTSPQELSEELSRRLQITPDSNGEQFSSLIQREPSSRLRSCSVTDAVAEQGHLPPPSVAYVHTTPGLP SGWEERKDAKGRTYYVNHNNRTTTWTRPIMQLAEDGASGSATNSNNHLIEPQIRRPRSLSSPTVTLSAPLEGAKDSPVRRAVKDTLSNPQ SPQPSPYNSPKPQHKVTQSFLPPGWEMRIAPNGRPFFIDHNTKTTTWEDPRLKFPVHMRSKTSLNPNDLGPLPPGWEERIHLDGRTFYID HNSKITQWEDPRLQNPAITGPAVPYSREFKQKYDYFRKKLKKPADIPNRFEMKLHRNNIFEESYRRIMSVKRPDVLKARLWIEFESEKGL DYGGVAREWFFLLSKEMFNPYYGLFEYSATAGDNSTVSFAIVQASPKDQGLYYCCIKNSYGKVTAEFNLTAEVLKQLSSRQDTKGCEEIE FSQLIFKEDFLHDSYFGGRLRGQIATEELHFGEGVHRKAFRSTVMHGLMPVFKPGHACVLKVHNAIAYGTRNNDELIQRNYKLAAQECYV QNTARYYAKIYAAEAQPLEGFGEVPEIIPIFLIHRPENNIPYATVEEELIGEFVKYSIRDGKEINFLRRESEAGQKCCTFQHWVYQKTSG CLLVTDMQGVGMKLTDVGIATLAKGYKGFKGNCSMTFIDQFKALHQCNKYCKMLGLKSLQNNNQKQKQPSIGKSKVQTNSMTIKKAGPET -------------------------------------------------------------- |
Top |
Fusion Gene PPI Analysis for NEDD4L-ALPK2 |
| Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in |
| Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160) |
| Hgene | Hgene's interactors | Tgene | Tgene's interactors |
| - Retained PPIs in in-frame fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Still interaction with |
| - Lost PPIs in in-frame fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Interaction lost with |
| - Retained PPIs, but lost function due to frame-shift fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Interaction lost with |
Top |
Related Drugs for NEDD4L-ALPK2 |
| Drugs targeting genes involved in this fusion gene. (DrugBank Version 5.1.8 2021-05-08) |
| Partner | Gene | UniProtAcc | DrugBank ID | Drug name | Drug activity | Drug type | Drug status |
Top |
Related Diseases for NEDD4L-ALPK2 |
| Diseases associated with fusion partners. (DisGeNet 4.0) |
| Partner | Gene | Disease ID | Disease name | # pubmeds | Source |
Copyright 2021-Present -The University of Texas Health Science Center at Houston (UTHealth)
Web File Viewing | Emergency Information |Campus Carry|Site Policies