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Center for Computational Systems Medicine
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Fusion Gene Summary

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Fusion Gene ORF analysis

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Fusion Genomic Features

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Fusion Protein Features

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Fusion Gene Sequence

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Fusion Gene PPI analysis

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Related Drugs

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Related Diseases

Fusion gene:NEDD4L-TBC1D17 (FusionGDB2 ID:58431)

Fusion Gene Summary for NEDD4L-TBC1D17

check button Fusion gene summary
Fusion gene informationFusion gene name: NEDD4L-TBC1D17
Fusion gene ID: 58431
HgeneTgene
Gene symbol

NEDD4L

TBC1D17

Gene ID

23327

79735

Gene nameNEDD4 like E3 ubiquitin protein ligaseTBC1 domain family member 17
SynonymsNEDD4-2|NEDD4.2|PVNH7|RSP5|hNEDD4-2-
Cytomap

18q21.31

19q13.33

Type of geneprotein-codingprotein-coding
DescriptionE3 ubiquitin-protein ligase NEDD4-likeHECT-type E3 ubiquitin transferase NED4Lneural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligaseubiquitin-protein ligase Rsp5TBC1 domain family member 17
Modification date2020032920200313
UniProtAcc

Q96PU5

.
Ensembl transtripts involved in fusion geneENST00000256830, ENST00000356462, 
ENST00000357895, ENST00000382850, 
ENST00000400345, ENST00000586263, 
ENST00000256832, ENST00000431212, 
ENST00000435432, ENST00000456173, 
ENST00000456986, ENST00000588516, 
ENST00000589054, 		ENST00000598789, 
ENST00000535102, ENST00000221543, 
Fusion gene scores* DoF score28 X 18 X 11=55448 X 40 X 11=3520
# samples 3532
** MAII scorelog2(35/5544*10)=-3.98550043030488
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0		log2(32/3520*10)=-3.4594316186373
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0
Context

PubMed: NEDD4L [Title/Abstract] AND TBC1D17 [Title/Abstract] AND fusion [Title/Abstract]

Most frequent breakpointNEDD4L(55919286)-TBC1D17(50381755), # samples:2
Anticipated loss of major functional domain due to fusion event.
* DoF score (Degree of Frequency) = # partners X # break points X # cancer types
** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)

check button Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez
PartnerGeneGO IDGO termPubMed ID
HgeneNEDD4L

GO:0003254

regulation of membrane depolarization

15217910

HgeneNEDD4L

GO:0006511

ubiquitin-dependent protein catabolic process

21463633

HgeneNEDD4L

GO:0010038

response to metal ion

11244092

HgeneNEDD4L

GO:0016567

protein ubiquitination

15217910|25631046

HgeneNEDD4L

GO:0034765

regulation of ion transmembrane transport

17289006

HgeneNEDD4L

GO:0042391

regulation of membrane potential

17289006

HgeneNEDD4L

GO:0043161

proteasome-mediated ubiquitin-dependent protein catabolic process

21463633

HgeneNEDD4L

GO:0060306

regulation of membrane repolarization

21463633

HgeneNEDD4L

GO:0070936

protein K48-linked ubiquitination

21463633

HgeneNEDD4L

GO:1901016

regulation of potassium ion transmembrane transporter activity

17289006

HgeneNEDD4L

GO:1901017

negative regulation of potassium ion transmembrane transporter activity

21463633

HgeneNEDD4L

GO:1901380

negative regulation of potassium ion transmembrane transport

21463633

HgeneNEDD4L

GO:1902306

negative regulation of sodium ion transmembrane transport

15217910

HgeneNEDD4L

GO:1903861

positive regulation of dendrite extension

23999003

HgeneNEDD4L

GO:2000009

negative regulation of protein localization to cell surface

21463633

HgeneNEDD4L

GO:2000650

negative regulation of sodium ion transmembrane transporter activity

15217910


check buttonFusion gene breakpoints across NEDD4L (5'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check buttonFusion gene breakpoints across TBC1D17 (3'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check button Fusion gene information from two resources (ChiTars 5.0 and ChimerDB 4.0)
* All genome coordinats were lifted-over on hg19.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
SourceDiseaseSampleHgeneHchrHbpHstrandTgeneTchrTbpTstrand
ChimerDB4OVTCGA-24-1551-01ANEDD4Lchr18

55919286

+TBC1D17chr19

50381400

+
ChimerDB4OVTCGA-24-1551-01ANEDD4Lchr18

55919286

+TBC1D17chr19

50381755

+


Top

Fusion Gene ORF analysis for NEDD4L-TBC1D17

check button Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
ORFHenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrand
5CDS-3UTRENST00000256830ENST00000598789NEDD4Lchr18

55919286

+TBC1D17chr19

50381400

+
5CDS-3UTRENST00000256830ENST00000598789NEDD4Lchr18

55919286

+TBC1D17chr19

50381755

+
5CDS-3UTRENST00000356462ENST00000598789NEDD4Lchr18

55919286

+TBC1D17chr19

50381400

+
5CDS-3UTRENST00000356462ENST00000598789NEDD4Lchr18

55919286

+TBC1D17chr19

50381755

+
5CDS-3UTRENST00000357895ENST00000598789NEDD4Lchr18

55919286

+TBC1D17chr19

50381400

+
5CDS-3UTRENST00000357895ENST00000598789NEDD4Lchr18

55919286

+TBC1D17chr19

50381755

+
5CDS-3UTRENST00000382850ENST00000598789NEDD4Lchr18

55919286

+TBC1D17chr19

50381400

+
5CDS-3UTRENST00000382850ENST00000598789NEDD4Lchr18

55919286

+TBC1D17chr19

50381755

+
5CDS-3UTRENST00000400345ENST00000598789NEDD4Lchr18

55919286

+TBC1D17chr19

50381400

+
5CDS-3UTRENST00000400345ENST00000598789NEDD4Lchr18

55919286

+TBC1D17chr19

50381755

+
5CDS-3UTRENST00000586263ENST00000598789NEDD4Lchr18

55919286

+TBC1D17chr19

50381400

+
5CDS-3UTRENST00000586263ENST00000598789NEDD4Lchr18

55919286

+TBC1D17chr19

50381755

+
5CDS-intronENST00000256830ENST00000535102NEDD4Lchr18

55919286

+TBC1D17chr19

50381400

+
5CDS-intronENST00000356462ENST00000535102NEDD4Lchr18

55919286

+TBC1D17chr19

50381400

+
5CDS-intronENST00000357895ENST00000535102NEDD4Lchr18

55919286

+TBC1D17chr19

50381400

+
5CDS-intronENST00000382850ENST00000535102NEDD4Lchr18

55919286

+TBC1D17chr19

50381400

+
5CDS-intronENST00000400345ENST00000535102NEDD4Lchr18

55919286

+TBC1D17chr19

50381400

+
5CDS-intronENST00000586263ENST00000535102NEDD4Lchr18

55919286

+TBC1D17chr19

50381400

+
5UTR-3CDSENST00000256832ENST00000221543NEDD4Lchr18

55919286

+TBC1D17chr19

50381400

+
5UTR-3CDSENST00000256832ENST00000221543NEDD4Lchr18

55919286

+TBC1D17chr19

50381755

+
5UTR-3CDSENST00000256832ENST00000535102NEDD4Lchr18

55919286

+TBC1D17chr19

50381755

+
5UTR-3CDSENST00000431212ENST00000221543NEDD4Lchr18

55919286

+TBC1D17chr19

50381400

+
5UTR-3CDSENST00000431212ENST00000221543NEDD4Lchr18

55919286

+TBC1D17chr19

50381755

+
5UTR-3CDSENST00000431212ENST00000535102NEDD4Lchr18

55919286

+TBC1D17chr19

50381755

+
5UTR-3CDSENST00000435432ENST00000221543NEDD4Lchr18

55919286

+TBC1D17chr19

50381400

+
5UTR-3CDSENST00000435432ENST00000221543NEDD4Lchr18

55919286

+TBC1D17chr19

50381755

+
5UTR-3CDSENST00000435432ENST00000535102NEDD4Lchr18

55919286

+TBC1D17chr19

50381755

+
5UTR-3CDSENST00000456173ENST00000221543NEDD4Lchr18

55919286

+TBC1D17chr19

50381400

+
5UTR-3CDSENST00000456173ENST00000221543NEDD4Lchr18

55919286

+TBC1D17chr19

50381755

+
5UTR-3CDSENST00000456173ENST00000535102NEDD4Lchr18

55919286

+TBC1D17chr19

50381755

+
5UTR-3CDSENST00000456986ENST00000221543NEDD4Lchr18

55919286

+TBC1D17chr19

50381400

+
5UTR-3CDSENST00000456986ENST00000221543NEDD4Lchr18

55919286

+TBC1D17chr19

50381755

+
5UTR-3CDSENST00000456986ENST00000535102NEDD4Lchr18

55919286

+TBC1D17chr19

50381755

+
5UTR-3UTRENST00000256832ENST00000598789NEDD4Lchr18

55919286

+TBC1D17chr19

50381400

+
5UTR-3UTRENST00000256832ENST00000598789NEDD4Lchr18

55919286

+TBC1D17chr19

50381755

+
5UTR-3UTRENST00000431212ENST00000598789NEDD4Lchr18

55919286

+TBC1D17chr19

50381400

+
5UTR-3UTRENST00000431212ENST00000598789NEDD4Lchr18

55919286

+TBC1D17chr19

50381755

+
5UTR-3UTRENST00000435432ENST00000598789NEDD4Lchr18

55919286

+TBC1D17chr19

50381400

+
5UTR-3UTRENST00000435432ENST00000598789NEDD4Lchr18

55919286

+TBC1D17chr19

50381755

+
5UTR-3UTRENST00000456173ENST00000598789NEDD4Lchr18

55919286

+TBC1D17chr19

50381400

+
5UTR-3UTRENST00000456173ENST00000598789NEDD4Lchr18

55919286

+TBC1D17chr19

50381755

+
5UTR-3UTRENST00000456986ENST00000598789NEDD4Lchr18

55919286

+TBC1D17chr19

50381400

+
5UTR-3UTRENST00000456986ENST00000598789NEDD4Lchr18

55919286

+TBC1D17chr19

50381755

+
5UTR-intronENST00000256832ENST00000535102NEDD4Lchr18

55919286

+TBC1D17chr19

50381400

+
5UTR-intronENST00000431212ENST00000535102NEDD4Lchr18

55919286

+TBC1D17chr19

50381400

+
5UTR-intronENST00000435432ENST00000535102NEDD4Lchr18

55919286

+TBC1D17chr19

50381400

+
5UTR-intronENST00000456173ENST00000535102NEDD4Lchr18

55919286

+TBC1D17chr19

50381400

+
5UTR-intronENST00000456986ENST00000535102NEDD4Lchr18

55919286

+TBC1D17chr19

50381400

+
In-frameENST00000256830ENST00000221543NEDD4Lchr18

55919286

+TBC1D17chr19

50381400

+
In-frameENST00000256830ENST00000221543NEDD4Lchr18

55919286

+TBC1D17chr19

50381755

+
In-frameENST00000256830ENST00000535102NEDD4Lchr18

55919286

+TBC1D17chr19

50381755

+
In-frameENST00000356462ENST00000221543NEDD4Lchr18

55919286

+TBC1D17chr19

50381400

+
In-frameENST00000356462ENST00000221543NEDD4Lchr18

55919286

+TBC1D17chr19

50381755

+
In-frameENST00000356462ENST00000535102NEDD4Lchr18

55919286

+TBC1D17chr19

50381755

+
In-frameENST00000357895ENST00000221543NEDD4Lchr18

55919286

+TBC1D17chr19

50381400

+
In-frameENST00000357895ENST00000221543NEDD4Lchr18

55919286

+TBC1D17chr19

50381755

+
In-frameENST00000357895ENST00000535102NEDD4Lchr18

55919286

+TBC1D17chr19

50381755

+
In-frameENST00000382850ENST00000221543NEDD4Lchr18

55919286

+TBC1D17chr19

50381400

+
In-frameENST00000382850ENST00000221543NEDD4Lchr18

55919286

+TBC1D17chr19

50381755

+
In-frameENST00000382850ENST00000535102NEDD4Lchr18

55919286

+TBC1D17chr19

50381755

+
In-frameENST00000400345ENST00000221543NEDD4Lchr18

55919286

+TBC1D17chr19

50381400

+
In-frameENST00000400345ENST00000221543NEDD4Lchr18

55919286

+TBC1D17chr19

50381755

+
In-frameENST00000400345ENST00000535102NEDD4Lchr18

55919286

+TBC1D17chr19

50381755

+
In-frameENST00000586263ENST00000221543NEDD4Lchr18

55919286

+TBC1D17chr19

50381400

+
In-frameENST00000586263ENST00000221543NEDD4Lchr18

55919286

+TBC1D17chr19

50381755

+
In-frameENST00000586263ENST00000535102NEDD4Lchr18

55919286

+TBC1D17chr19

50381755

+
intron-3CDSENST00000588516ENST00000221543NEDD4Lchr18

55919286

+TBC1D17chr19

50381400

+
intron-3CDSENST00000588516ENST00000221543NEDD4Lchr18

55919286

+TBC1D17chr19

50381755

+
intron-3CDSENST00000588516ENST00000535102NEDD4Lchr18

55919286

+TBC1D17chr19

50381755

+
intron-3CDSENST00000589054ENST00000221543NEDD4Lchr18

55919286

+TBC1D17chr19

50381400

+
intron-3CDSENST00000589054ENST00000221543NEDD4Lchr18

55919286

+TBC1D17chr19

50381755

+
intron-3CDSENST00000589054ENST00000535102NEDD4Lchr18

55919286

+TBC1D17chr19

50381755

+
intron-3UTRENST00000588516ENST00000598789NEDD4Lchr18

55919286

+TBC1D17chr19

50381400

+
intron-3UTRENST00000588516ENST00000598789NEDD4Lchr18

55919286

+TBC1D17chr19

50381755

+
intron-3UTRENST00000589054ENST00000598789NEDD4Lchr18

55919286

+TBC1D17chr19

50381400

+
intron-3UTRENST00000589054ENST00000598789NEDD4Lchr18

55919286

+TBC1D17chr19

50381755

+
intron-intronENST00000588516ENST00000535102NEDD4Lchr18

55919286

+TBC1D17chr19

50381400

+
intron-intronENST00000589054ENST00000535102NEDD4Lchr18

55919286

+TBC1D17chr19

50381400

+

check buttonORFfinder result based on the fusion transcript sequence of in-frame fusion genes.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandSeq length
(transcript)		BP loci
(transcript)		Predicted start
(transcript)		Predicted stop
(transcript)		Seq length
(amino acids)
ENST00000356462NEDD4Lchr1855919286+ENST00000221543TBC1D17chr1950381755+25385912102417735
ENST00000356462NEDD4Lchr1855919286+ENST00000535102TBC1D17chr1950381755+25375912102417735
ENST00000400345NEDD4Lchr1855919286+ENST00000221543TBC1D17chr1950381755+25275801992406735
ENST00000400345NEDD4Lchr1855919286+ENST00000535102TBC1D17chr1950381755+25265801992406735
ENST00000382850NEDD4Lchr1855919286+ENST00000221543TBC1D17chr1950381755+2357410292236735
ENST00000382850NEDD4Lchr1855919286+ENST00000535102TBC1D17chr1950381755+2356410292236735
ENST00000256830NEDD4Lchr1855919286+ENST00000221543TBC1D17chr1950381755+224429702123707
ENST00000256830NEDD4Lchr1855919286+ENST00000535102TBC1D17chr1950381755+224329702123707
ENST00000357895NEDD4Lchr1855919286+ENST00000221543TBC1D17chr1950381755+24234762032302699
ENST00000357895NEDD4Lchr1855919286+ENST00000535102TBC1D17chr1950381755+24224762032302699
ENST00000586263NEDD4Lchr1855919286+ENST00000221543TBC1D17chr1950381755+24194721992298699
ENST00000586263NEDD4Lchr1855919286+ENST00000535102TBC1D17chr1950381755+24184721992298699
ENST00000356462NEDD4Lchr1855919286+ENST00000221543TBC1D17chr1950381400+26375912102516768
ENST00000400345NEDD4Lchr1855919286+ENST00000221543TBC1D17chr1950381400+26265801992505768
ENST00000382850NEDD4Lchr1855919286+ENST00000221543TBC1D17chr1950381400+2456410292335768
ENST00000256830NEDD4Lchr1855919286+ENST00000221543TBC1D17chr1950381400+234329702222740
ENST00000357895NEDD4Lchr1855919286+ENST00000221543TBC1D17chr1950381400+25224762032401732
ENST00000586263NEDD4Lchr1855919286+ENST00000221543TBC1D17chr1950381400+25184721992397732

check buttonDeepORF prediction of the coding potential based on the fusion transcript sequence of in-frame fusion genes. DeepORF is a coding potential classifier based on convolutional neural network by comparing the real Ribo-seq data. If the no-coding score < 0.5 and coding score > 0.5, then the in-frame fusion transcript is predicted as being likely translated.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandNo-coding scoreCoding score
ENST00000356462ENST00000221543NEDD4Lchr1855919286+TBC1D17chr1950381755+0.0157833530.9842166
ENST00000356462ENST00000535102NEDD4Lchr1855919286+TBC1D17chr1950381755+0.0156809050.98431903
ENST00000400345ENST00000221543NEDD4Lchr1855919286+TBC1D17chr1950381755+0.0152116340.9847884
ENST00000400345ENST00000535102NEDD4Lchr1855919286+TBC1D17chr1950381755+0.0151180130.98488194
ENST00000382850ENST00000221543NEDD4Lchr1855919286+TBC1D17chr1950381755+0.0171704940.9828295
ENST00000382850ENST00000535102NEDD4Lchr1855919286+TBC1D17chr1950381755+0.0170780890.98292184
ENST00000256830ENST00000221543NEDD4Lchr1855919286+TBC1D17chr1950381755+0.0170921650.98290783
ENST00000256830ENST00000535102NEDD4Lchr1855919286+TBC1D17chr1950381755+0.0169795640.9830205
ENST00000357895ENST00000221543NEDD4Lchr1855919286+TBC1D17chr1950381755+0.0152854040.98471457
ENST00000357895ENST00000535102NEDD4Lchr1855919286+TBC1D17chr1950381755+0.0152239460.9847761
ENST00000586263ENST00000221543NEDD4Lchr1855919286+TBC1D17chr1950381755+0.0151855180.98481447
ENST00000586263ENST00000535102NEDD4Lchr1855919286+TBC1D17chr1950381755+0.0151243220.98487574
ENST00000356462ENST00000221543NEDD4Lchr1855919286+TBC1D17chr1950381400+0.0131490230.9868509
ENST00000400345ENST00000221543NEDD4Lchr1855919286+TBC1D17chr1950381400+0.0126698650.9873302
ENST00000382850ENST00000221543NEDD4Lchr1855919286+TBC1D17chr1950381400+0.0143267390.9856733
ENST00000256830ENST00000221543NEDD4Lchr1855919286+TBC1D17chr1950381400+0.0141553670.9858446
ENST00000357895ENST00000221543NEDD4Lchr1855919286+TBC1D17chr1950381400+0.006319360.9936806
ENST00000586263ENST00000221543NEDD4Lchr1855919286+TBC1D17chr1950381400+0.0062950960.99370486

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Fusion Genomic Features for NEDD4L-TBC1D17


check buttonFusionAI prediction of the potential fusion gene breakpoint based on the pre-mature RNA sequence context (+/- 5kb of individual partner genes, total 20kb length sequence). FusionAI is a fusion gene breakpoint classifier based on convolutional neural network by comparing the fusion positive and negative sequence context of ~ 20K fusion gene data. From here, we can have the relative potentency of the 20K genomic sequence how individual sequnce will be likely used as the gene fusion breakpoints.
HgeneHchrHbpHstrandTgeneTchrTbpTstrand1-pp (fusion gene breakpoint)
NEDD4Lchr1855919286+TBC1D17chr1950381754+0.0008125720.9991874
NEDD4Lchr1855919286+TBC1D17chr1950381399+4.88E-050.99995124
NEDD4Lchr1855919286+TBC1D17chr1950381754+0.0008125720.9991874
NEDD4Lchr1855919286+TBC1D17chr1950381399+4.88E-050.99995124

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions. We integrated a total of 44 different types of human genomic feature loci information across five big categories including virus integration sites, repeats, structural variants, chromatin states, and gene expression regulation. More details are in help page.
genomic feature

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions that are ovelapped with the top 1% feature importance score regions. More details are in help page.
genomic feature of top 1%

Top

Fusion Protein Features for NEDD4L-TBC1D17


check button Four levels of functional features of fusion genes
Go to FGviewer search page for the most frequent breakpoint (https://ccsmweb.uth.edu/FGviewer/chr18:55919286/chr19:50381755)
- FGviewer provides the online visualization of the retention search of the protein functional features across DNA, RNA, protein, and pathological levels.
- How to search
1. Put your fusion gene symbol.
2. Press the tab key until there will be shown the breakpoint information filled.
4. Go down and press 'Search' tab twice.
4. Go down to have the hyperlink of the search result.
5. Click the hyperlink.
6. See the FGviewer result for your fusion gene.
FGviewer

check buttonMain function of each fusion partner protein. (from UniProt)
HgeneTgene
NEDD4L

Q96PU5

.
FUNCTION: E3 ubiquitin-protein ligase which accepts ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfers the ubiquitin to targeted substrates. Inhibits TGF-beta signaling by triggering SMAD2 and TGFBR1 ubiquitination and proteasome-dependent degradation. Promotes ubiquitination and internalization of various plasma membrane channels such as ENaC, SCN2A/Nav1.2, SCN3A/Nav1.3, SCN5A/Nav1.5, SCN9A/Nav1.7, SCN10A/Nav1.8, KCNA3/Kv1.3, KCNH2, EAAT1, KCNQ2/Kv7.2, KCNQ3/Kv7.3 or CLC5 (PubMed:26363003, PubMed:27445338). Promotes ubiquitination and degradation of SGK1 and TNK2. Ubiquitinates BRAT1 and this ubiquitination is enhanced in the presence of NDFIP1 (PubMed:25631046). Plays a role in dendrite formation by melanocytes (PubMed:23999003). Involved in the regulation of TOR signaling (PubMed:27694961). Ubiquitinates and regulates protein levels of NTRK1 once this one is activated by NGF (PubMed:27445338). {ECO:0000250|UniProtKB:Q8CFI0, ECO:0000269|PubMed:12911626, ECO:0000269|PubMed:15040001, ECO:0000269|PubMed:15217910, ECO:0000269|PubMed:15489223, ECO:0000269|PubMed:15496141, ECO:0000269|PubMed:15576372, ECO:0000269|PubMed:19144635, ECO:0000269|PubMed:23999003, ECO:0000269|PubMed:25631046, ECO:0000269|PubMed:26363003, ECO:0000269|PubMed:27445338, ECO:0000269|PubMed:27694961}.FUNCTION: Transcriptional activator which is required for calcium-dependent dendritic growth and branching in cortical neurons. Recruits CREB-binding protein (CREBBP) to nuclear bodies. Component of the CREST-BRG1 complex, a multiprotein complex that regulates promoter activation by orchestrating a calcium-dependent release of a repressor complex and a recruitment of an activator complex. In resting neurons, transcription of the c-FOS promoter is inhibited by BRG1-dependent recruitment of a phospho-RB1-HDAC1 repressor complex. Upon calcium influx, RB1 is dephosphorylated by calcineurin, which leads to release of the repressor complex. At the same time, there is increased recruitment of CREBBP to the promoter by a CREST-dependent mechanism, which leads to transcriptional activation. The CREST-BRG1 complex also binds to the NR2B promoter, and activity-dependent induction of NR2B expression involves a release of HDAC1 and recruitment of CREBBP (By similarity). {ECO:0000250}.

check buttonRetention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at

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* Minus value of BPloci means that the break pointn is located before the CDS.
- In-frame and retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
TgeneTBC1D17chr18:55919286chr19:50381400ENST00000221543017596_6317649.0Compositional biasNote=Pro-rich
TgeneTBC1D17chr18:55919286chr19:50381400ENST00000535102016596_6310616.0Compositional biasNote=Pro-rich
TgeneTBC1D17chr18:55919286chr19:50381755ENST00000221543117596_63140649.0Compositional biasNote=Pro-rich
TgeneTBC1D17chr18:55919286chr19:50381755ENST00000535102016596_6317616.0Compositional biasNote=Pro-rich
TgeneTBC1D17chr18:55919286chr19:50381400ENST00000221543017310_5207649.0DomainRab-GAP TBC
TgeneTBC1D17chr18:55919286chr19:50381400ENST00000535102016310_5200616.0DomainRab-GAP TBC
TgeneTBC1D17chr18:55919286chr19:50381755ENST00000221543117310_52040649.0DomainRab-GAP TBC
TgeneTBC1D17chr18:55919286chr19:50381755ENST00000535102016310_5207616.0DomainRab-GAP TBC

- In-frame and not-retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneNEDD4Lchr18:55919286chr19:50381400ENST00000256830+528193_22699872.0DomainWW 1
HgeneNEDD4Lchr18:55919286chr19:50381400ENST00000256830+528385_41899872.0DomainWW 2
HgeneNEDD4Lchr18:55919286chr19:50381400ENST00000256830+528497_53099872.0DomainWW 3
HgeneNEDD4Lchr18:55919286chr19:50381400ENST00000256830+5284_12699872.0DomainC2
HgeneNEDD4Lchr18:55919286chr19:50381400ENST00000256830+528548_58199872.0DomainWW 4
HgeneNEDD4Lchr18:55919286chr19:50381400ENST00000256830+528640_97499872.0DomainHECT
HgeneNEDD4Lchr18:55919286chr19:50381400ENST00000356462+529193_22699912.0DomainWW 1
HgeneNEDD4Lchr18:55919286chr19:50381400ENST00000356462+529385_41899912.0DomainWW 2
HgeneNEDD4Lchr18:55919286chr19:50381400ENST00000356462+529497_53099912.0DomainWW 3
HgeneNEDD4Lchr18:55919286chr19:50381400ENST00000356462+5294_12699912.0DomainC2
HgeneNEDD4Lchr18:55919286chr19:50381400ENST00000356462+529548_58199912.0DomainWW 4
HgeneNEDD4Lchr18:55919286chr19:50381400ENST00000356462+529640_97499912.0DomainHECT
HgeneNEDD4Lchr18:55919286chr19:50381400ENST00000357895+531193_22691968.0DomainWW 1
HgeneNEDD4Lchr18:55919286chr19:50381400ENST00000357895+531385_41891968.0DomainWW 2
HgeneNEDD4Lchr18:55919286chr19:50381400ENST00000357895+531497_53091968.0DomainWW 3
HgeneNEDD4Lchr18:55919286chr19:50381400ENST00000357895+5314_12691968.0DomainC2
HgeneNEDD4Lchr18:55919286chr19:50381400ENST00000357895+531548_58191968.0DomainWW 4
HgeneNEDD4Lchr18:55919286chr19:50381400ENST00000357895+531640_97491968.0DomainHECT
HgeneNEDD4Lchr18:55919286chr19:50381400ENST00000382850+530193_22699956.0DomainWW 1
HgeneNEDD4Lchr18:55919286chr19:50381400ENST00000382850+530385_41899956.0DomainWW 2
HgeneNEDD4Lchr18:55919286chr19:50381400ENST00000382850+530497_53099956.0DomainWW 3
HgeneNEDD4Lchr18:55919286chr19:50381400ENST00000382850+5304_12699956.0DomainC2
HgeneNEDD4Lchr18:55919286chr19:50381400ENST00000382850+530548_58199956.0DomainWW 4
HgeneNEDD4Lchr18:55919286chr19:50381400ENST00000382850+530640_97499956.0DomainHECT
HgeneNEDD4Lchr18:55919286chr19:50381400ENST00000400345+531193_22699976.0DomainWW 1
HgeneNEDD4Lchr18:55919286chr19:50381400ENST00000400345+531385_41899976.0DomainWW 2
HgeneNEDD4Lchr18:55919286chr19:50381400ENST00000400345+531497_53099976.0DomainWW 3
HgeneNEDD4Lchr18:55919286chr19:50381400ENST00000400345+5314_12699976.0DomainC2
HgeneNEDD4Lchr18:55919286chr19:50381400ENST00000400345+531548_58199976.0DomainWW 4
HgeneNEDD4Lchr18:55919286chr19:50381400ENST00000400345+531640_97499976.0DomainHECT
HgeneNEDD4Lchr18:55919286chr19:50381400ENST00000431212+430193_2260855.0DomainWW 1
HgeneNEDD4Lchr18:55919286chr19:50381400ENST00000431212+430385_4180855.0DomainWW 2
HgeneNEDD4Lchr18:55919286chr19:50381400ENST00000431212+430497_5300855.0DomainWW 3
HgeneNEDD4Lchr18:55919286chr19:50381400ENST00000431212+4304_1260855.0DomainC2
HgeneNEDD4Lchr18:55919286chr19:50381400ENST00000431212+430548_5810855.0DomainWW 4
HgeneNEDD4Lchr18:55919286chr19:50381400ENST00000431212+430640_9740855.0DomainHECT
HgeneNEDD4Lchr18:55919286chr19:50381400ENST00000435432+631193_2260835.0DomainWW 1
HgeneNEDD4Lchr18:55919286chr19:50381400ENST00000435432+631385_4180835.0DomainWW 2
HgeneNEDD4Lchr18:55919286chr19:50381400ENST00000435432+631497_5300835.0DomainWW 3
HgeneNEDD4Lchr18:55919286chr19:50381400ENST00000435432+6314_1260835.0DomainC2
HgeneNEDD4Lchr18:55919286chr19:50381400ENST00000435432+631548_5810835.0DomainWW 4
HgeneNEDD4Lchr18:55919286chr19:50381400ENST00000435432+631640_9740835.0DomainHECT
HgeneNEDD4Lchr18:55919286chr19:50381400ENST00000456173+429193_2260835.0DomainWW 1
HgeneNEDD4Lchr18:55919286chr19:50381400ENST00000456173+429385_4180835.0DomainWW 2
HgeneNEDD4Lchr18:55919286chr19:50381400ENST00000456173+429497_5300835.0DomainWW 3
HgeneNEDD4Lchr18:55919286chr19:50381400ENST00000456173+4294_1260835.0DomainC2
HgeneNEDD4Lchr18:55919286chr19:50381400ENST00000456173+429548_5810835.0DomainWW 4
HgeneNEDD4Lchr18:55919286chr19:50381400ENST00000456173+429640_9740835.0DomainHECT
HgeneNEDD4Lchr18:55919286chr19:50381400ENST00000456986+531193_2260855.0DomainWW 1
HgeneNEDD4Lchr18:55919286chr19:50381400ENST00000456986+531385_4180855.0DomainWW 2
HgeneNEDD4Lchr18:55919286chr19:50381400ENST00000456986+531497_5300855.0DomainWW 3
HgeneNEDD4Lchr18:55919286chr19:50381400ENST00000456986+5314_1260855.0DomainC2
HgeneNEDD4Lchr18:55919286chr19:50381400ENST00000456986+531548_5810855.0DomainWW 4
HgeneNEDD4Lchr18:55919286chr19:50381400ENST00000456986+531640_9740855.0DomainHECT
HgeneNEDD4Lchr18:55919286chr19:50381400ENST00000586263+530193_22691948.0DomainWW 1
HgeneNEDD4Lchr18:55919286chr19:50381400ENST00000586263+530385_41891948.0DomainWW 2
HgeneNEDD4Lchr18:55919286chr19:50381400ENST00000586263+530497_53091948.0DomainWW 3
HgeneNEDD4Lchr18:55919286chr19:50381400ENST00000586263+5304_12691948.0DomainC2
HgeneNEDD4Lchr18:55919286chr19:50381400ENST00000586263+530548_58191948.0DomainWW 4
HgeneNEDD4Lchr18:55919286chr19:50381400ENST00000586263+530640_97491948.0DomainHECT
HgeneNEDD4Lchr18:55919286chr19:50381755ENST00000256830+528193_22699872.0DomainWW 1
HgeneNEDD4Lchr18:55919286chr19:50381755ENST00000256830+528385_41899872.0DomainWW 2
HgeneNEDD4Lchr18:55919286chr19:50381755ENST00000256830+528497_53099872.0DomainWW 3
HgeneNEDD4Lchr18:55919286chr19:50381755ENST00000256830+5284_12699872.0DomainC2
HgeneNEDD4Lchr18:55919286chr19:50381755ENST00000256830+528548_58199872.0DomainWW 4
HgeneNEDD4Lchr18:55919286chr19:50381755ENST00000256830+528640_97499872.0DomainHECT
HgeneNEDD4Lchr18:55919286chr19:50381755ENST00000356462+529193_22699912.0DomainWW 1
HgeneNEDD4Lchr18:55919286chr19:50381755ENST00000356462+529385_41899912.0DomainWW 2
HgeneNEDD4Lchr18:55919286chr19:50381755ENST00000356462+529497_53099912.0DomainWW 3
HgeneNEDD4Lchr18:55919286chr19:50381755ENST00000356462+5294_12699912.0DomainC2
HgeneNEDD4Lchr18:55919286chr19:50381755ENST00000356462+529548_58199912.0DomainWW 4
HgeneNEDD4Lchr18:55919286chr19:50381755ENST00000356462+529640_97499912.0DomainHECT
HgeneNEDD4Lchr18:55919286chr19:50381755ENST00000357895+531193_22691968.0DomainWW 1
HgeneNEDD4Lchr18:55919286chr19:50381755ENST00000357895+531385_41891968.0DomainWW 2
HgeneNEDD4Lchr18:55919286chr19:50381755ENST00000357895+531497_53091968.0DomainWW 3
HgeneNEDD4Lchr18:55919286chr19:50381755ENST00000357895+5314_12691968.0DomainC2
HgeneNEDD4Lchr18:55919286chr19:50381755ENST00000357895+531548_58191968.0DomainWW 4
HgeneNEDD4Lchr18:55919286chr19:50381755ENST00000357895+531640_97491968.0DomainHECT
HgeneNEDD4Lchr18:55919286chr19:50381755ENST00000382850+530193_22699956.0DomainWW 1
HgeneNEDD4Lchr18:55919286chr19:50381755ENST00000382850+530385_41899956.0DomainWW 2
HgeneNEDD4Lchr18:55919286chr19:50381755ENST00000382850+530497_53099956.0DomainWW 3
HgeneNEDD4Lchr18:55919286chr19:50381755ENST00000382850+5304_12699956.0DomainC2
HgeneNEDD4Lchr18:55919286chr19:50381755ENST00000382850+530548_58199956.0DomainWW 4
HgeneNEDD4Lchr18:55919286chr19:50381755ENST00000382850+530640_97499956.0DomainHECT
HgeneNEDD4Lchr18:55919286chr19:50381755ENST00000400345+531193_22699976.0DomainWW 1
HgeneNEDD4Lchr18:55919286chr19:50381755ENST00000400345+531385_41899976.0DomainWW 2
HgeneNEDD4Lchr18:55919286chr19:50381755ENST00000400345+531497_53099976.0DomainWW 3
HgeneNEDD4Lchr18:55919286chr19:50381755ENST00000400345+5314_12699976.0DomainC2
HgeneNEDD4Lchr18:55919286chr19:50381755ENST00000400345+531548_58199976.0DomainWW 4
HgeneNEDD4Lchr18:55919286chr19:50381755ENST00000400345+531640_97499976.0DomainHECT
HgeneNEDD4Lchr18:55919286chr19:50381755ENST00000431212+430193_2260855.0DomainWW 1
HgeneNEDD4Lchr18:55919286chr19:50381755ENST00000431212+430385_4180855.0DomainWW 2
HgeneNEDD4Lchr18:55919286chr19:50381755ENST00000431212+430497_5300855.0DomainWW 3
HgeneNEDD4Lchr18:55919286chr19:50381755ENST00000431212+4304_1260855.0DomainC2
HgeneNEDD4Lchr18:55919286chr19:50381755ENST00000431212+430548_5810855.0DomainWW 4
HgeneNEDD4Lchr18:55919286chr19:50381755ENST00000431212+430640_9740855.0DomainHECT
HgeneNEDD4Lchr18:55919286chr19:50381755ENST00000435432+631193_2260835.0DomainWW 1
HgeneNEDD4Lchr18:55919286chr19:50381755ENST00000435432+631385_4180835.0DomainWW 2
HgeneNEDD4Lchr18:55919286chr19:50381755ENST00000435432+631497_5300835.0DomainWW 3
HgeneNEDD4Lchr18:55919286chr19:50381755ENST00000435432+6314_1260835.0DomainC2
HgeneNEDD4Lchr18:55919286chr19:50381755ENST00000435432+631548_5810835.0DomainWW 4
HgeneNEDD4Lchr18:55919286chr19:50381755ENST00000435432+631640_9740835.0DomainHECT
HgeneNEDD4Lchr18:55919286chr19:50381755ENST00000456173+429193_2260835.0DomainWW 1
HgeneNEDD4Lchr18:55919286chr19:50381755ENST00000456173+429385_4180835.0DomainWW 2
HgeneNEDD4Lchr18:55919286chr19:50381755ENST00000456173+429497_5300835.0DomainWW 3
HgeneNEDD4Lchr18:55919286chr19:50381755ENST00000456173+4294_1260835.0DomainC2
HgeneNEDD4Lchr18:55919286chr19:50381755ENST00000456173+429548_5810835.0DomainWW 4
HgeneNEDD4Lchr18:55919286chr19:50381755ENST00000456173+429640_9740835.0DomainHECT
HgeneNEDD4Lchr18:55919286chr19:50381755ENST00000456986+531193_2260855.0DomainWW 1
HgeneNEDD4Lchr18:55919286chr19:50381755ENST00000456986+531385_4180855.0DomainWW 2
HgeneNEDD4Lchr18:55919286chr19:50381755ENST00000456986+531497_5300855.0DomainWW 3
HgeneNEDD4Lchr18:55919286chr19:50381755ENST00000456986+5314_1260855.0DomainC2
HgeneNEDD4Lchr18:55919286chr19:50381755ENST00000456986+531548_5810855.0DomainWW 4
HgeneNEDD4Lchr18:55919286chr19:50381755ENST00000456986+531640_9740855.0DomainHECT
HgeneNEDD4Lchr18:55919286chr19:50381755ENST00000586263+530193_22691948.0DomainWW 1
HgeneNEDD4Lchr18:55919286chr19:50381755ENST00000586263+530385_41891948.0DomainWW 2
HgeneNEDD4Lchr18:55919286chr19:50381755ENST00000586263+530497_53091948.0DomainWW 3
HgeneNEDD4Lchr18:55919286chr19:50381755ENST00000586263+5304_12691948.0DomainC2
HgeneNEDD4Lchr18:55919286chr19:50381755ENST00000586263+530548_58191948.0DomainWW 4
HgeneNEDD4Lchr18:55919286chr19:50381755ENST00000586263+530640_97491948.0DomainHECT


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Fusion Gene Sequence for NEDD4L-TBC1D17


check button For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. To have fusion amino acid sequence, we ran ORFfinder and chose the longest ORF among the all predicted ones.
>58431_58431_1_NEDD4L-TBC1D17_NEDD4L_chr18_55919286_ENST00000256830_TBC1D17_chr19_50381400_ENST00000221543_length(transcript)=2343nt_BP=297nt
ATGGCGACCGGGCTCGGGGAGCCGGTCTATGGACTTTCCGAAGACGAGGGAGAGTCCCGTATTCTCAGAGTAAAAGTTGTTTCTGGAATT
GATCTCGCCAAAAAGGACATCTTTGGAGCCAGTGATCCGTATGTGAAACTTTCATTGTACGTAGCGGATGAGAATAGAGAACTTGCTTTG
GTCCAGACAAAAACAATTAAAAAGACACTGAACCCAAAATGGAATGAAGAATTTTATTTCAGGGTAAACCCATCTAATCACAGACTCCTA
TTTGAAGTATTTGACGAAAATAGACTGGTGGTGTTTGAGAAGGGCGGAGTGTACCTGCACACCAGCGCTAAGAAGTATCAGGACCGAGAC
TCTCTCATCGCTGGTGTCATCCGTGTCGTGGAAAAGGACAATGACGTCCTCCTGCACTGGGCTCCTGTAGAGGAGGCTGGAGATTCCACC
CAAATCCTCTTCTCCAAGAAGGACTCCAGTGGGGGTGACTCATGTGCTTCTGAGGAGGAACCAACCTTTGACCCCGACTATGAACCTGAC
TGGGCTGTCATCAGCACTGTGCGGCCACAGCTCTGCCACTCAGAGCCCACGAGAGGTGCAGAGCCCAGCTGCCCCCAGGGCTCCTGGGCC
TTCTCAGTGAGTCTGGGGGAGCTAAAGTCCATCCGCCGCTCCAAGCCAGGCCTCAGCTGGGCCTACCTGGTTCTGGTGACCCAGGCTGGA
GGTTCCCTGCCCGCACTGCACTTCCACCGCGGGGGCACCCGCGCCCTGCTCCGCGTCCTCAGCCGCTACCTGCTGTTGGCCAGCTCCCCG
CAGGACTCCCGCCTCTACCTTGTCTTCCCCCACGACTCCTCTGCTCTCTCCAACTCCTTCCACCACCTGCAGCTCTTTGACCAGGACAGC
TCCAATGTGGTGTCACGCTTCCTCCAGGATCCCTACTCCACCACCTTCAGCAGCTTCTCCCGAGTGACCAACTTCTTCCGGGGTGCCCTG
CAGCCACAGCCTGAGGGAGCCGCCTCCGACCTTCCCCCGCCACCCGACGATGAGCCCGAGCCTGGATTCGAGGTCATTTCCTGTGTGGAG
CTGGGGCCTCGGCCAACCGTGGAGCGGGGCCCTCCAGTTACAGAGGAGGAGTGGGCACGCCACGTGGGCCCTGAAGGTCGCCTGCAGCAG
GTCCCTGAGCTGAAGAACCGGATCTTCTCGGGGGGTCTGAGCCCCAGCCTGCGGCGCGAGGCCTGGAAGTTCCTCCTAGGGTACCTCAGC
TGGGAAGGCACAGCTGAGGAGCACAAGGCCCACATACGCAAGAAAACGGATGAGTATTTCCGCATGAAGCTGCAGTGGAAATCTGTGAGC
CCTGAGCAGGAGCGGAGAAACTCACTTCTGCATGGATACCGCAGCCTCATCGAAAGGGATGTGAGCCGCACTGACAGGACCAACAAGTTC
TACGAGGGTCCCGAGAACCCGGGGCTGGGCCTGCTGAACGATATCCTCCTCACCTACTGCATGTATCACTTCGACCTCGGCTACGTCCAG
GGCATGAGTGATCTTCTCTCCCCGATCCTCTACGTCATTCAGAACGAGGTGGATGCTTTCTGGTGTTTCTGTGGCTTCATGGAGCTCGTG
CAAGGGAACTTTGAAGAGAGCCAGGAGACCATGAAGCGGCAACTCGGGCGACTGCTGCTGCTCCTGAGGGTGCTGGACCCCCTGCTCTGC
GACTTCCTGGATTCCCAGGACTCCGGCTCTCTCTGCTTCTGTTTCCGGTGGCTGCTCATCTGGTTCAAGAGGGAATTCCCCTTCCCGGAT
GTCCTTCGGCTGTGGGAGGTGCTGTGGACAGGGCTCCCTGGCCCCAATCTGCACCTGCTGGTGGCCTGCGCCATCCTGGACATGGAGAGG
GACACCCTCATGCTGTCCGGCTTCGGCTCCAATGAGATCCTCAAGCACATCAACGAGCTGACTATGAAGCTGAGCGTGGAGGACGTGCTG
ACCCGCGCCGAGGCCCTGCACCGCCAGCTAACCGCCTGCCCCGAGCTGCCCCACAACGTGCAGGAGATCCTGGGGCTGGCCCCGCCCGCA
GAGCCCCACAGCCCCTCGCCCACCGCCTCCCCGCTGCCTCTGTCGCCCACCCGGGCCCCGCCCACCCCGCCGCCCTCCACGGACACAGCC
CCGCAGCCCGACAGCAGCCTGGAGATCCTGCCCGAGGAGGAGGACGAGGGCGCCGACTCCTAACCCCGCCAGGCAGCCTCGTTCTGCACA
GGCACTTTAGCCCGAGCCAGGCACACCTGCGAGGGGGCAGGTGTGCTCCGCCGCCCTGCTGATAAGCTGGCTTCATTAAACTGACACTTC

>58431_58431_1_NEDD4L-TBC1D17_NEDD4L_chr18_55919286_ENST00000256830_TBC1D17_chr19_50381400_ENST00000221543_length(amino acids)=740AA_BP=99
MATGLGEPVYGLSEDEGESRILRVKVVSGIDLAKKDIFGASDPYVKLSLYVADENRELALVQTKTIKKTLNPKWNEEFYFRVNPSNHRLL
FEVFDENRLVVFEKGGVYLHTSAKKYQDRDSLIAGVIRVVEKDNDVLLHWAPVEEAGDSTQILFSKKDSSGGDSCASEEEPTFDPDYEPD
WAVISTVRPQLCHSEPTRGAEPSCPQGSWAFSVSLGELKSIRRSKPGLSWAYLVLVTQAGGSLPALHFHRGGTRALLRVLSRYLLLASSP
QDSRLYLVFPHDSSALSNSFHHLQLFDQDSSNVVSRFLQDPYSTTFSSFSRVTNFFRGALQPQPEGAASDLPPPPDDEPEPGFEVISCVE
LGPRPTVERGPPVTEEEWARHVGPEGRLQQVPELKNRIFSGGLSPSLRREAWKFLLGYLSWEGTAEEHKAHIRKKTDEYFRMKLQWKSVS
PEQERRNSLLHGYRSLIERDVSRTDRTNKFYEGPENPGLGLLNDILLTYCMYHFDLGYVQGMSDLLSPILYVIQNEVDAFWCFCGFMELV
QGNFEESQETMKRQLGRLLLLLRVLDPLLCDFLDSQDSGSLCFCFRWLLIWFKREFPFPDVLRLWEVLWTGLPGPNLHLLVACAILDMER
DTLMLSGFGSNEILKHINELTMKLSVEDVLTRAEALHRQLTACPELPHNVQEILGLAPPAEPHSPSPTASPLPLSPTRAPPTPPPSTDTA

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>58431_58431_2_NEDD4L-TBC1D17_NEDD4L_chr18_55919286_ENST00000256830_TBC1D17_chr19_50381755_ENST00000221543_length(transcript)=2244nt_BP=297nt
ATGGCGACCGGGCTCGGGGAGCCGGTCTATGGACTTTCCGAAGACGAGGGAGAGTCCCGTATTCTCAGAGTAAAAGTTGTTTCTGGAATT
GATCTCGCCAAAAAGGACATCTTTGGAGCCAGTGATCCGTATGTGAAACTTTCATTGTACGTAGCGGATGAGAATAGAGAACTTGCTTTG
GTCCAGACAAAAACAATTAAAAAGACACTGAACCCAAAATGGAATGAAGAATTTTATTTCAGGGTAAACCCATCTAATCACAGACTCCTA
TTTGAAGTATTTGACGAAAATAGACTGGACAATGACGTCCTCCTGCACTGGGCTCCTGTAGAGGAGGCTGGAGATTCCACCCAAATCCTC
TTCTCCAAGAAGGACTCCAGTGGGGGTGACTCATGTGCTTCTGAGGAGGAACCAACCTTTGACCCCGACTATGAACCTGACTGGGCTGTC
ATCAGCACTGTGCGGCCACAGCTCTGCCACTCAGAGCCCACGAGAGGTGCAGAGCCCAGCTGCCCCCAGGGCTCCTGGGCCTTCTCAGTG
AGTCTGGGGGAGCTAAAGTCCATCCGCCGCTCCAAGCCAGGCCTCAGCTGGGCCTACCTGGTTCTGGTGACCCAGGCTGGAGGTTCCCTG
CCCGCACTGCACTTCCACCGCGGGGGCACCCGCGCCCTGCTCCGCGTCCTCAGCCGCTACCTGCTGTTGGCCAGCTCCCCGCAGGACTCC
CGCCTCTACCTTGTCTTCCCCCACGACTCCTCTGCTCTCTCCAACTCCTTCCACCACCTGCAGCTCTTTGACCAGGACAGCTCCAATGTG
GTGTCACGCTTCCTCCAGGATCCCTACTCCACCACCTTCAGCAGCTTCTCCCGAGTGACCAACTTCTTCCGGGGTGCCCTGCAGCCACAG
CCTGAGGGAGCCGCCTCCGACCTTCCCCCGCCACCCGACGATGAGCCCGAGCCTGGATTCGAGGTCATTTCCTGTGTGGAGCTGGGGCCT
CGGCCAACCGTGGAGCGGGGCCCTCCAGTTACAGAGGAGGAGTGGGCACGCCACGTGGGCCCTGAAGGTCGCCTGCAGCAGGTCCCTGAG
CTGAAGAACCGGATCTTCTCGGGGGGTCTGAGCCCCAGCCTGCGGCGCGAGGCCTGGAAGTTCCTCCTAGGGTACCTCAGCTGGGAAGGC
ACAGCTGAGGAGCACAAGGCCCACATACGCAAGAAAACGGATGAGTATTTCCGCATGAAGCTGCAGTGGAAATCTGTGAGCCCTGAGCAG
GAGCGGAGAAACTCACTTCTGCATGGATACCGCAGCCTCATCGAAAGGGATGTGAGCCGCACTGACAGGACCAACAAGTTCTACGAGGGT
CCCGAGAACCCGGGGCTGGGCCTGCTGAACGATATCCTCCTCACCTACTGCATGTATCACTTCGACCTCGGCTACGTCCAGGGCATGAGT
GATCTTCTCTCCCCGATCCTCTACGTCATTCAGAACGAGGTGGATGCTTTCTGGTGTTTCTGTGGCTTCATGGAGCTCGTGCAAGGGAAC
TTTGAAGAGAGCCAGGAGACCATGAAGCGGCAACTCGGGCGACTGCTGCTGCTCCTGAGGGTGCTGGACCCCCTGCTCTGCGACTTCCTG
GATTCCCAGGACTCCGGCTCTCTCTGCTTCTGTTTCCGGTGGCTGCTCATCTGGTTCAAGAGGGAATTCCCCTTCCCGGATGTCCTTCGG
CTGTGGGAGGTGCTGTGGACAGGGCTCCCTGGCCCCAATCTGCACCTGCTGGTGGCCTGCGCCATCCTGGACATGGAGAGGGACACCCTC
ATGCTGTCCGGCTTCGGCTCCAATGAGATCCTCAAGCACATCAACGAGCTGACTATGAAGCTGAGCGTGGAGGACGTGCTGACCCGCGCC
GAGGCCCTGCACCGCCAGCTAACCGCCTGCCCCGAGCTGCCCCACAACGTGCAGGAGATCCTGGGGCTGGCCCCGCCCGCAGAGCCCCAC
AGCCCCTCGCCCACCGCCTCCCCGCTGCCTCTGTCGCCCACCCGGGCCCCGCCCACCCCGCCGCCCTCCACGGACACAGCCCCGCAGCCC
GACAGCAGCCTGGAGATCCTGCCCGAGGAGGAGGACGAGGGCGCCGACTCCTAACCCCGCCAGGCAGCCTCGTTCTGCACAGGCACTTTA

>58431_58431_2_NEDD4L-TBC1D17_NEDD4L_chr18_55919286_ENST00000256830_TBC1D17_chr19_50381755_ENST00000221543_length(amino acids)=707AA_BP=99
MATGLGEPVYGLSEDEGESRILRVKVVSGIDLAKKDIFGASDPYVKLSLYVADENRELALVQTKTIKKTLNPKWNEEFYFRVNPSNHRLL
FEVFDENRLDNDVLLHWAPVEEAGDSTQILFSKKDSSGGDSCASEEEPTFDPDYEPDWAVISTVRPQLCHSEPTRGAEPSCPQGSWAFSV
SLGELKSIRRSKPGLSWAYLVLVTQAGGSLPALHFHRGGTRALLRVLSRYLLLASSPQDSRLYLVFPHDSSALSNSFHHLQLFDQDSSNV
VSRFLQDPYSTTFSSFSRVTNFFRGALQPQPEGAASDLPPPPDDEPEPGFEVISCVELGPRPTVERGPPVTEEEWARHVGPEGRLQQVPE
LKNRIFSGGLSPSLRREAWKFLLGYLSWEGTAEEHKAHIRKKTDEYFRMKLQWKSVSPEQERRNSLLHGYRSLIERDVSRTDRTNKFYEG
PENPGLGLLNDILLTYCMYHFDLGYVQGMSDLLSPILYVIQNEVDAFWCFCGFMELVQGNFEESQETMKRQLGRLLLLLRVLDPLLCDFL
DSQDSGSLCFCFRWLLIWFKREFPFPDVLRLWEVLWTGLPGPNLHLLVACAILDMERDTLMLSGFGSNEILKHINELTMKLSVEDVLTRA

--------------------------------------------------------------
>58431_58431_3_NEDD4L-TBC1D17_NEDD4L_chr18_55919286_ENST00000256830_TBC1D17_chr19_50381755_ENST00000535102_length(transcript)=2243nt_BP=297nt
ATGGCGACCGGGCTCGGGGAGCCGGTCTATGGACTTTCCGAAGACGAGGGAGAGTCCCGTATTCTCAGAGTAAAAGTTGTTTCTGGAATT
GATCTCGCCAAAAAGGACATCTTTGGAGCCAGTGATCCGTATGTGAAACTTTCATTGTACGTAGCGGATGAGAATAGAGAACTTGCTTTG
GTCCAGACAAAAACAATTAAAAAGACACTGAACCCAAAATGGAATGAAGAATTTTATTTCAGGGTAAACCCATCTAATCACAGACTCCTA
TTTGAAGTATTTGACGAAAATAGACTGGACAATGACGTCCTCCTGCACTGGGCTCCTGTAGAGGAGGCTGGAGATTCCACCCAAATCCTC
TTCTCCAAGAAGGACTCCAGTGGGGGTGACTCATGTGCTTCTGAGGAGGAACCAACCTTTGACCCCGACTATGAACCTGACTGGGCTGTC
ATCAGCACTGTGCGGCCACAGCTCTGCCACTCAGAGCCCACGAGAGGTGCAGAGCCCAGCTGCCCCCAGGGCTCCTGGGCCTTCTCAGTG
AGTCTGGGGGAGCTAAAGTCCATCCGCCGCTCCAAGCCAGGCCTCAGCTGGGCCTACCTGGTTCTGGTGACCCAGGCTGGAGGTTCCCTG
CCCGCACTGCACTTCCACCGCGGGGGCACCCGCGCCCTGCTCCGCGTCCTCAGCCGCTACCTGCTGTTGGCCAGCTCCCCGCAGGACTCC
CGCCTCTACCTTGTCTTCCCCCACGACTCCTCTGCTCTCTCCAACTCCTTCCACCACCTGCAGCTCTTTGACCAGGACAGCTCCAATGTG
GTGTCACGCTTCCTCCAGGATCCCTACTCCACCACCTTCAGCAGCTTCTCCCGAGTGACCAACTTCTTCCGGGGTGCCCTGCAGCCACAG
CCTGAGGGAGCCGCCTCCGACCTTCCCCCGCCACCCGACGATGAGCCCGAGCCTGGATTCGAGGTCATTTCCTGTGTGGAGCTGGGGCCT
CGGCCAACCGTGGAGCGGGGCCCTCCAGTTACAGAGGAGGAGTGGGCACGCCACGTGGGCCCTGAAGGTCGCCTGCAGCAGGTCCCTGAG
CTGAAGAACCGGATCTTCTCGGGGGGTCTGAGCCCCAGCCTGCGGCGCGAGGCCTGGAAGTTCCTCCTAGGGTACCTCAGCTGGGAAGGC
ACAGCTGAGGAGCACAAGGCCCACATACGCAAGAAAACGGATGAGTATTTCCGCATGAAGCTGCAGTGGAAATCTGTGAGCCCTGAGCAG
GAGCGGAGAAACTCACTTCTGCATGGATACCGCAGCCTCATCGAAAGGGATGTGAGCCGCACTGACAGGACCAACAAGTTCTACGAGGGT
CCCGAGAACCCGGGGCTGGGCCTGCTGAACGATATCCTCCTCACCTACTGCATGTATCACTTCGACCTCGGCTACGTCCAGGGCATGAGT
GATCTTCTCTCCCCGATCCTCTACGTCATTCAGAACGAGGTGGATGCTTTCTGGTGTTTCTGTGGCTTCATGGAGCTCGTGCAAGGGAAC
TTTGAAGAGAGCCAGGAGACCATGAAGCGGCAACTCGGGCGACTGCTGCTGCTCCTGAGGGTGCTGGACCCCCTGCTCTGCGACTTCCTG
GATTCCCAGGACTCCGGCTCTCTCTGCTTCTGTTTCCGGTGGCTGCTCATCTGGTTCAAGAGGGAATTCCCCTTCCCGGATGTCCTTCGG
CTGTGGGAGGTGCTGTGGACAGGGCTCCCTGGCCCCAATCTGCACCTGCTGGTGGCCTGCGCCATCCTGGACATGGAGAGGGACACCCTC
ATGCTGTCCGGCTTCGGCTCCAATGAGATCCTCAAGCACATCAACGAGCTGACTATGAAGCTGAGCGTGGAGGACGTGCTGACCCGCGCC
GAGGCCCTGCACCGCCAGCTAACCGCCTGCCCCGAGCTGCCCCACAACGTGCAGGAGATCCTGGGGCTGGCCCCGCCCGCAGAGCCCCAC
AGCCCCTCGCCCACCGCCTCCCCGCTGCCTCTGTCGCCCACCCGGGCCCCGCCCACCCCGCCGCCCTCCACGGACACAGCCCCGCAGCCC
GACAGCAGCCTGGAGATCCTGCCCGAGGAGGAGGACGAGGGCGCCGACTCCTAACCCCGCCAGGCAGCCTCGTTCTGCACAGGCACTTTA

>58431_58431_3_NEDD4L-TBC1D17_NEDD4L_chr18_55919286_ENST00000256830_TBC1D17_chr19_50381755_ENST00000535102_length(amino acids)=707AA_BP=99
MATGLGEPVYGLSEDEGESRILRVKVVSGIDLAKKDIFGASDPYVKLSLYVADENRELALVQTKTIKKTLNPKWNEEFYFRVNPSNHRLL
FEVFDENRLDNDVLLHWAPVEEAGDSTQILFSKKDSSGGDSCASEEEPTFDPDYEPDWAVISTVRPQLCHSEPTRGAEPSCPQGSWAFSV
SLGELKSIRRSKPGLSWAYLVLVTQAGGSLPALHFHRGGTRALLRVLSRYLLLASSPQDSRLYLVFPHDSSALSNSFHHLQLFDQDSSNV
VSRFLQDPYSTTFSSFSRVTNFFRGALQPQPEGAASDLPPPPDDEPEPGFEVISCVELGPRPTVERGPPVTEEEWARHVGPEGRLQQVPE
LKNRIFSGGLSPSLRREAWKFLLGYLSWEGTAEEHKAHIRKKTDEYFRMKLQWKSVSPEQERRNSLLHGYRSLIERDVSRTDRTNKFYEG
PENPGLGLLNDILLTYCMYHFDLGYVQGMSDLLSPILYVIQNEVDAFWCFCGFMELVQGNFEESQETMKRQLGRLLLLLRVLDPLLCDFL
DSQDSGSLCFCFRWLLIWFKREFPFPDVLRLWEVLWTGLPGPNLHLLVACAILDMERDTLMLSGFGSNEILKHINELTMKLSVEDVLTRA

--------------------------------------------------------------
>58431_58431_4_NEDD4L-TBC1D17_NEDD4L_chr18_55919286_ENST00000356462_TBC1D17_chr19_50381400_ENST00000221543_length(transcript)=2637nt_BP=591nt
GCGCCGCCGCCGCGCGCAGTGAGAGGCGCCGGGGCTGCCGCCCGGTGCTCGGCGCGCTCTCGGGAGCCGCCCGCCCGCTGGTCCCGCAGC
CTTCCGGGAGGAAGCGGTGCCGGCAGCGTCCAGGGCGCGCTCTCGGGCACCCTCACCTGCCGGCGCCCGGCCGCTTACCCGGCAGGGCGT
GCGCAGGGTAGGGTGCGGGACCGGGGGGACCTGGAGGCAGAGGGGAGAACCGGCCGTCCGCGCCGCAGCACAGCCGCTGGGAGCGCCTCA
GACCCCGCGCGGGGCGCCGGCTCCATGGCGACCGGGCTCGGGGAGCCGGTCTATGGACTTTCCGAAGACGAGGGAGAGTCCCGTATTCTC
AGAGTAAAAGTTGTTTCTGGAATTGATCTCGCCAAAAAGGACATCTTTGGAGCCAGTGATCCGTATGTGAAACTTTCATTGTACGTAGCG
GATGAGAATAGAGAACTTGCTTTGGTCCAGACAAAAACAATTAAAAAGACACTGAACCCAAAATGGAATGAAGAATTTTATTTCAGGGTA
AACCCATCTAATCACAGACTCCTATTTGAAGTATTTGACGAAAATAGACTGGTGGTGTTTGAGAAGGGCGGAGTGTACCTGCACACCAGC
GCTAAGAAGTATCAGGACCGAGACTCTCTCATCGCTGGTGTCATCCGTGTCGTGGAAAAGGACAATGACGTCCTCCTGCACTGGGCTCCT
GTAGAGGAGGCTGGAGATTCCACCCAAATCCTCTTCTCCAAGAAGGACTCCAGTGGGGGTGACTCATGTGCTTCTGAGGAGGAACCAACC
TTTGACCCCGACTATGAACCTGACTGGGCTGTCATCAGCACTGTGCGGCCACAGCTCTGCCACTCAGAGCCCACGAGAGGTGCAGAGCCC
AGCTGCCCCCAGGGCTCCTGGGCCTTCTCAGTGAGTCTGGGGGAGCTAAAGTCCATCCGCCGCTCCAAGCCAGGCCTCAGCTGGGCCTAC
CTGGTTCTGGTGACCCAGGCTGGAGGTTCCCTGCCCGCACTGCACTTCCACCGCGGGGGCACCCGCGCCCTGCTCCGCGTCCTCAGCCGC
TACCTGCTGTTGGCCAGCTCCCCGCAGGACTCCCGCCTCTACCTTGTCTTCCCCCACGACTCCTCTGCTCTCTCCAACTCCTTCCACCAC
CTGCAGCTCTTTGACCAGGACAGCTCCAATGTGGTGTCACGCTTCCTCCAGGATCCCTACTCCACCACCTTCAGCAGCTTCTCCCGAGTG
ACCAACTTCTTCCGGGGTGCCCTGCAGCCACAGCCTGAGGGAGCCGCCTCCGACCTTCCCCCGCCACCCGACGATGAGCCCGAGCCTGGA
TTCGAGGTCATTTCCTGTGTGGAGCTGGGGCCTCGGCCAACCGTGGAGCGGGGCCCTCCAGTTACAGAGGAGGAGTGGGCACGCCACGTG
GGCCCTGAAGGTCGCCTGCAGCAGGTCCCTGAGCTGAAGAACCGGATCTTCTCGGGGGGTCTGAGCCCCAGCCTGCGGCGCGAGGCCTGG
AAGTTCCTCCTAGGGTACCTCAGCTGGGAAGGCACAGCTGAGGAGCACAAGGCCCACATACGCAAGAAAACGGATGAGTATTTCCGCATG
AAGCTGCAGTGGAAATCTGTGAGCCCTGAGCAGGAGCGGAGAAACTCACTTCTGCATGGATACCGCAGCCTCATCGAAAGGGATGTGAGC
CGCACTGACAGGACCAACAAGTTCTACGAGGGTCCCGAGAACCCGGGGCTGGGCCTGCTGAACGATATCCTCCTCACCTACTGCATGTAT
CACTTCGACCTCGGCTACGTCCAGGGCATGAGTGATCTTCTCTCCCCGATCCTCTACGTCATTCAGAACGAGGTGGATGCTTTCTGGTGT
TTCTGTGGCTTCATGGAGCTCGTGCAAGGGAACTTTGAAGAGAGCCAGGAGACCATGAAGCGGCAACTCGGGCGACTGCTGCTGCTCCTG
AGGGTGCTGGACCCCCTGCTCTGCGACTTCCTGGATTCCCAGGACTCCGGCTCTCTCTGCTTCTGTTTCCGGTGGCTGCTCATCTGGTTC
AAGAGGGAATTCCCCTTCCCGGATGTCCTTCGGCTGTGGGAGGTGCTGTGGACAGGGCTCCCTGGCCCCAATCTGCACCTGCTGGTGGCC
TGCGCCATCCTGGACATGGAGAGGGACACCCTCATGCTGTCCGGCTTCGGCTCCAATGAGATCCTCAAGCACATCAACGAGCTGACTATG
AAGCTGAGCGTGGAGGACGTGCTGACCCGCGCCGAGGCCCTGCACCGCCAGCTAACCGCCTGCCCCGAGCTGCCCCACAACGTGCAGGAG
ATCCTGGGGCTGGCCCCGCCCGCAGAGCCCCACAGCCCCTCGCCCACCGCCTCCCCGCTGCCTCTGTCGCCCACCCGGGCCCCGCCCACC
CCGCCGCCCTCCACGGACACAGCCCCGCAGCCCGACAGCAGCCTGGAGATCCTGCCCGAGGAGGAGGACGAGGGCGCCGACTCCTAACCC
CGCCAGGCAGCCTCGTTCTGCACAGGCACTTTAGCCCGAGCCAGGCACACCTGCGAGGGGGCAGGTGTGCTCCGCCGCCCTGCTGATAAG

>58431_58431_4_NEDD4L-TBC1D17_NEDD4L_chr18_55919286_ENST00000356462_TBC1D17_chr19_50381400_ENST00000221543_length(amino acids)=768AA_BP=127
MEAEGRTGRPRRSTAAGSASDPARGAGSMATGLGEPVYGLSEDEGESRILRVKVVSGIDLAKKDIFGASDPYVKLSLYVADENRELALVQ
TKTIKKTLNPKWNEEFYFRVNPSNHRLLFEVFDENRLVVFEKGGVYLHTSAKKYQDRDSLIAGVIRVVEKDNDVLLHWAPVEEAGDSTQI
LFSKKDSSGGDSCASEEEPTFDPDYEPDWAVISTVRPQLCHSEPTRGAEPSCPQGSWAFSVSLGELKSIRRSKPGLSWAYLVLVTQAGGS
LPALHFHRGGTRALLRVLSRYLLLASSPQDSRLYLVFPHDSSALSNSFHHLQLFDQDSSNVVSRFLQDPYSTTFSSFSRVTNFFRGALQP
QPEGAASDLPPPPDDEPEPGFEVISCVELGPRPTVERGPPVTEEEWARHVGPEGRLQQVPELKNRIFSGGLSPSLRREAWKFLLGYLSWE
GTAEEHKAHIRKKTDEYFRMKLQWKSVSPEQERRNSLLHGYRSLIERDVSRTDRTNKFYEGPENPGLGLLNDILLTYCMYHFDLGYVQGM
SDLLSPILYVIQNEVDAFWCFCGFMELVQGNFEESQETMKRQLGRLLLLLRVLDPLLCDFLDSQDSGSLCFCFRWLLIWFKREFPFPDVL
RLWEVLWTGLPGPNLHLLVACAILDMERDTLMLSGFGSNEILKHINELTMKLSVEDVLTRAEALHRQLTACPELPHNVQEILGLAPPAEP

--------------------------------------------------------------
>58431_58431_5_NEDD4L-TBC1D17_NEDD4L_chr18_55919286_ENST00000356462_TBC1D17_chr19_50381755_ENST00000221543_length(transcript)=2538nt_BP=591nt
GCGCCGCCGCCGCGCGCAGTGAGAGGCGCCGGGGCTGCCGCCCGGTGCTCGGCGCGCTCTCGGGAGCCGCCCGCCCGCTGGTCCCGCAGC
CTTCCGGGAGGAAGCGGTGCCGGCAGCGTCCAGGGCGCGCTCTCGGGCACCCTCACCTGCCGGCGCCCGGCCGCTTACCCGGCAGGGCGT
GCGCAGGGTAGGGTGCGGGACCGGGGGGACCTGGAGGCAGAGGGGAGAACCGGCCGTCCGCGCCGCAGCACAGCCGCTGGGAGCGCCTCA
GACCCCGCGCGGGGCGCCGGCTCCATGGCGACCGGGCTCGGGGAGCCGGTCTATGGACTTTCCGAAGACGAGGGAGAGTCCCGTATTCTC
AGAGTAAAAGTTGTTTCTGGAATTGATCTCGCCAAAAAGGACATCTTTGGAGCCAGTGATCCGTATGTGAAACTTTCATTGTACGTAGCG
GATGAGAATAGAGAACTTGCTTTGGTCCAGACAAAAACAATTAAAAAGACACTGAACCCAAAATGGAATGAAGAATTTTATTTCAGGGTA
AACCCATCTAATCACAGACTCCTATTTGAAGTATTTGACGAAAATAGACTGGACAATGACGTCCTCCTGCACTGGGCTCCTGTAGAGGAG
GCTGGAGATTCCACCCAAATCCTCTTCTCCAAGAAGGACTCCAGTGGGGGTGACTCATGTGCTTCTGAGGAGGAACCAACCTTTGACCCC
GACTATGAACCTGACTGGGCTGTCATCAGCACTGTGCGGCCACAGCTCTGCCACTCAGAGCCCACGAGAGGTGCAGAGCCCAGCTGCCCC
CAGGGCTCCTGGGCCTTCTCAGTGAGTCTGGGGGAGCTAAAGTCCATCCGCCGCTCCAAGCCAGGCCTCAGCTGGGCCTACCTGGTTCTG
GTGACCCAGGCTGGAGGTTCCCTGCCCGCACTGCACTTCCACCGCGGGGGCACCCGCGCCCTGCTCCGCGTCCTCAGCCGCTACCTGCTG
TTGGCCAGCTCCCCGCAGGACTCCCGCCTCTACCTTGTCTTCCCCCACGACTCCTCTGCTCTCTCCAACTCCTTCCACCACCTGCAGCTC
TTTGACCAGGACAGCTCCAATGTGGTGTCACGCTTCCTCCAGGATCCCTACTCCACCACCTTCAGCAGCTTCTCCCGAGTGACCAACTTC
TTCCGGGGTGCCCTGCAGCCACAGCCTGAGGGAGCCGCCTCCGACCTTCCCCCGCCACCCGACGATGAGCCCGAGCCTGGATTCGAGGTC
ATTTCCTGTGTGGAGCTGGGGCCTCGGCCAACCGTGGAGCGGGGCCCTCCAGTTACAGAGGAGGAGTGGGCACGCCACGTGGGCCCTGAA
GGTCGCCTGCAGCAGGTCCCTGAGCTGAAGAACCGGATCTTCTCGGGGGGTCTGAGCCCCAGCCTGCGGCGCGAGGCCTGGAAGTTCCTC
CTAGGGTACCTCAGCTGGGAAGGCACAGCTGAGGAGCACAAGGCCCACATACGCAAGAAAACGGATGAGTATTTCCGCATGAAGCTGCAG
TGGAAATCTGTGAGCCCTGAGCAGGAGCGGAGAAACTCACTTCTGCATGGATACCGCAGCCTCATCGAAAGGGATGTGAGCCGCACTGAC
AGGACCAACAAGTTCTACGAGGGTCCCGAGAACCCGGGGCTGGGCCTGCTGAACGATATCCTCCTCACCTACTGCATGTATCACTTCGAC
CTCGGCTACGTCCAGGGCATGAGTGATCTTCTCTCCCCGATCCTCTACGTCATTCAGAACGAGGTGGATGCTTTCTGGTGTTTCTGTGGC
TTCATGGAGCTCGTGCAAGGGAACTTTGAAGAGAGCCAGGAGACCATGAAGCGGCAACTCGGGCGACTGCTGCTGCTCCTGAGGGTGCTG
GACCCCCTGCTCTGCGACTTCCTGGATTCCCAGGACTCCGGCTCTCTCTGCTTCTGTTTCCGGTGGCTGCTCATCTGGTTCAAGAGGGAA
TTCCCCTTCCCGGATGTCCTTCGGCTGTGGGAGGTGCTGTGGACAGGGCTCCCTGGCCCCAATCTGCACCTGCTGGTGGCCTGCGCCATC
CTGGACATGGAGAGGGACACCCTCATGCTGTCCGGCTTCGGCTCCAATGAGATCCTCAAGCACATCAACGAGCTGACTATGAAGCTGAGC
GTGGAGGACGTGCTGACCCGCGCCGAGGCCCTGCACCGCCAGCTAACCGCCTGCCCCGAGCTGCCCCACAACGTGCAGGAGATCCTGGGG
CTGGCCCCGCCCGCAGAGCCCCACAGCCCCTCGCCCACCGCCTCCCCGCTGCCTCTGTCGCCCACCCGGGCCCCGCCCACCCCGCCGCCC
TCCACGGACACAGCCCCGCAGCCCGACAGCAGCCTGGAGATCCTGCCCGAGGAGGAGGACGAGGGCGCCGACTCCTAACCCCGCCAGGCA
GCCTCGTTCTGCACAGGCACTTTAGCCCGAGCCAGGCACACCTGCGAGGGGGCAGGTGTGCTCCGCCGCCCTGCTGATAAGCTGGCTTCA

>58431_58431_5_NEDD4L-TBC1D17_NEDD4L_chr18_55919286_ENST00000356462_TBC1D17_chr19_50381755_ENST00000221543_length(amino acids)=735AA_BP=127
MEAEGRTGRPRRSTAAGSASDPARGAGSMATGLGEPVYGLSEDEGESRILRVKVVSGIDLAKKDIFGASDPYVKLSLYVADENRELALVQ
TKTIKKTLNPKWNEEFYFRVNPSNHRLLFEVFDENRLDNDVLLHWAPVEEAGDSTQILFSKKDSSGGDSCASEEEPTFDPDYEPDWAVIS
TVRPQLCHSEPTRGAEPSCPQGSWAFSVSLGELKSIRRSKPGLSWAYLVLVTQAGGSLPALHFHRGGTRALLRVLSRYLLLASSPQDSRL
YLVFPHDSSALSNSFHHLQLFDQDSSNVVSRFLQDPYSTTFSSFSRVTNFFRGALQPQPEGAASDLPPPPDDEPEPGFEVISCVELGPRP
TVERGPPVTEEEWARHVGPEGRLQQVPELKNRIFSGGLSPSLRREAWKFLLGYLSWEGTAEEHKAHIRKKTDEYFRMKLQWKSVSPEQER
RNSLLHGYRSLIERDVSRTDRTNKFYEGPENPGLGLLNDILLTYCMYHFDLGYVQGMSDLLSPILYVIQNEVDAFWCFCGFMELVQGNFE
ESQETMKRQLGRLLLLLRVLDPLLCDFLDSQDSGSLCFCFRWLLIWFKREFPFPDVLRLWEVLWTGLPGPNLHLLVACAILDMERDTLML
SGFGSNEILKHINELTMKLSVEDVLTRAEALHRQLTACPELPHNVQEILGLAPPAEPHSPSPTASPLPLSPTRAPPTPPPSTDTAPQPDS

--------------------------------------------------------------
>58431_58431_6_NEDD4L-TBC1D17_NEDD4L_chr18_55919286_ENST00000356462_TBC1D17_chr19_50381755_ENST00000535102_length(transcript)=2537nt_BP=591nt
GCGCCGCCGCCGCGCGCAGTGAGAGGCGCCGGGGCTGCCGCCCGGTGCTCGGCGCGCTCTCGGGAGCCGCCCGCCCGCTGGTCCCGCAGC
CTTCCGGGAGGAAGCGGTGCCGGCAGCGTCCAGGGCGCGCTCTCGGGCACCCTCACCTGCCGGCGCCCGGCCGCTTACCCGGCAGGGCGT
GCGCAGGGTAGGGTGCGGGACCGGGGGGACCTGGAGGCAGAGGGGAGAACCGGCCGTCCGCGCCGCAGCACAGCCGCTGGGAGCGCCTCA
GACCCCGCGCGGGGCGCCGGCTCCATGGCGACCGGGCTCGGGGAGCCGGTCTATGGACTTTCCGAAGACGAGGGAGAGTCCCGTATTCTC
AGAGTAAAAGTTGTTTCTGGAATTGATCTCGCCAAAAAGGACATCTTTGGAGCCAGTGATCCGTATGTGAAACTTTCATTGTACGTAGCG
GATGAGAATAGAGAACTTGCTTTGGTCCAGACAAAAACAATTAAAAAGACACTGAACCCAAAATGGAATGAAGAATTTTATTTCAGGGTA
AACCCATCTAATCACAGACTCCTATTTGAAGTATTTGACGAAAATAGACTGGACAATGACGTCCTCCTGCACTGGGCTCCTGTAGAGGAG
GCTGGAGATTCCACCCAAATCCTCTTCTCCAAGAAGGACTCCAGTGGGGGTGACTCATGTGCTTCTGAGGAGGAACCAACCTTTGACCCC
GACTATGAACCTGACTGGGCTGTCATCAGCACTGTGCGGCCACAGCTCTGCCACTCAGAGCCCACGAGAGGTGCAGAGCCCAGCTGCCCC
CAGGGCTCCTGGGCCTTCTCAGTGAGTCTGGGGGAGCTAAAGTCCATCCGCCGCTCCAAGCCAGGCCTCAGCTGGGCCTACCTGGTTCTG
GTGACCCAGGCTGGAGGTTCCCTGCCCGCACTGCACTTCCACCGCGGGGGCACCCGCGCCCTGCTCCGCGTCCTCAGCCGCTACCTGCTG
TTGGCCAGCTCCCCGCAGGACTCCCGCCTCTACCTTGTCTTCCCCCACGACTCCTCTGCTCTCTCCAACTCCTTCCACCACCTGCAGCTC
TTTGACCAGGACAGCTCCAATGTGGTGTCACGCTTCCTCCAGGATCCCTACTCCACCACCTTCAGCAGCTTCTCCCGAGTGACCAACTTC
TTCCGGGGTGCCCTGCAGCCACAGCCTGAGGGAGCCGCCTCCGACCTTCCCCCGCCACCCGACGATGAGCCCGAGCCTGGATTCGAGGTC
ATTTCCTGTGTGGAGCTGGGGCCTCGGCCAACCGTGGAGCGGGGCCCTCCAGTTACAGAGGAGGAGTGGGCACGCCACGTGGGCCCTGAA
GGTCGCCTGCAGCAGGTCCCTGAGCTGAAGAACCGGATCTTCTCGGGGGGTCTGAGCCCCAGCCTGCGGCGCGAGGCCTGGAAGTTCCTC
CTAGGGTACCTCAGCTGGGAAGGCACAGCTGAGGAGCACAAGGCCCACATACGCAAGAAAACGGATGAGTATTTCCGCATGAAGCTGCAG
TGGAAATCTGTGAGCCCTGAGCAGGAGCGGAGAAACTCACTTCTGCATGGATACCGCAGCCTCATCGAAAGGGATGTGAGCCGCACTGAC
AGGACCAACAAGTTCTACGAGGGTCCCGAGAACCCGGGGCTGGGCCTGCTGAACGATATCCTCCTCACCTACTGCATGTATCACTTCGAC
CTCGGCTACGTCCAGGGCATGAGTGATCTTCTCTCCCCGATCCTCTACGTCATTCAGAACGAGGTGGATGCTTTCTGGTGTTTCTGTGGC
TTCATGGAGCTCGTGCAAGGGAACTTTGAAGAGAGCCAGGAGACCATGAAGCGGCAACTCGGGCGACTGCTGCTGCTCCTGAGGGTGCTG
GACCCCCTGCTCTGCGACTTCCTGGATTCCCAGGACTCCGGCTCTCTCTGCTTCTGTTTCCGGTGGCTGCTCATCTGGTTCAAGAGGGAA
TTCCCCTTCCCGGATGTCCTTCGGCTGTGGGAGGTGCTGTGGACAGGGCTCCCTGGCCCCAATCTGCACCTGCTGGTGGCCTGCGCCATC
CTGGACATGGAGAGGGACACCCTCATGCTGTCCGGCTTCGGCTCCAATGAGATCCTCAAGCACATCAACGAGCTGACTATGAAGCTGAGC
GTGGAGGACGTGCTGACCCGCGCCGAGGCCCTGCACCGCCAGCTAACCGCCTGCCCCGAGCTGCCCCACAACGTGCAGGAGATCCTGGGG
CTGGCCCCGCCCGCAGAGCCCCACAGCCCCTCGCCCACCGCCTCCCCGCTGCCTCTGTCGCCCACCCGGGCCCCGCCCACCCCGCCGCCC
TCCACGGACACAGCCCCGCAGCCCGACAGCAGCCTGGAGATCCTGCCCGAGGAGGAGGACGAGGGCGCCGACTCCTAACCCCGCCAGGCA
GCCTCGTTCTGCACAGGCACTTTAGCCCGAGCCAGGCACACCTGCGAGGGGGCAGGTGTGCTCCGCCGCCCTGCTGATAAGCTGGCTTCA

>58431_58431_6_NEDD4L-TBC1D17_NEDD4L_chr18_55919286_ENST00000356462_TBC1D17_chr19_50381755_ENST00000535102_length(amino acids)=735AA_BP=127
MEAEGRTGRPRRSTAAGSASDPARGAGSMATGLGEPVYGLSEDEGESRILRVKVVSGIDLAKKDIFGASDPYVKLSLYVADENRELALVQ
TKTIKKTLNPKWNEEFYFRVNPSNHRLLFEVFDENRLDNDVLLHWAPVEEAGDSTQILFSKKDSSGGDSCASEEEPTFDPDYEPDWAVIS
TVRPQLCHSEPTRGAEPSCPQGSWAFSVSLGELKSIRRSKPGLSWAYLVLVTQAGGSLPALHFHRGGTRALLRVLSRYLLLASSPQDSRL
YLVFPHDSSALSNSFHHLQLFDQDSSNVVSRFLQDPYSTTFSSFSRVTNFFRGALQPQPEGAASDLPPPPDDEPEPGFEVISCVELGPRP
TVERGPPVTEEEWARHVGPEGRLQQVPELKNRIFSGGLSPSLRREAWKFLLGYLSWEGTAEEHKAHIRKKTDEYFRMKLQWKSVSPEQER
RNSLLHGYRSLIERDVSRTDRTNKFYEGPENPGLGLLNDILLTYCMYHFDLGYVQGMSDLLSPILYVIQNEVDAFWCFCGFMELVQGNFE
ESQETMKRQLGRLLLLLRVLDPLLCDFLDSQDSGSLCFCFRWLLIWFKREFPFPDVLRLWEVLWTGLPGPNLHLLVACAILDMERDTLML
SGFGSNEILKHINELTMKLSVEDVLTRAEALHRQLTACPELPHNVQEILGLAPPAEPHSPSPTASPLPLSPTRAPPTPPPSTDTAPQPDS

--------------------------------------------------------------
>58431_58431_7_NEDD4L-TBC1D17_NEDD4L_chr18_55919286_ENST00000357895_TBC1D17_chr19_50381400_ENST00000221543_length(transcript)=2522nt_BP=476nt
GCCATTTCCAGAGAGGAACAACCGTGTAGACTGCTTTCCTGGGAGTCAAGTTAAAACTTCTCTCCTGTGACCTTGTCACCCGGCAGTGGA
AAGTTACCCTTGGCTGCAGCCACGACTTCCGCATACTCTTCAGAACTTGCTCTGCCCTTGAGTTTTCCAGCTTTCCTTTAATGCACTAAA
CCTTTAATATTGTATTCTCCTAAATGAGACGTCTCGCATTTGAGCAGGGAGAGTCCCGTATTCTCAGAGTAAAAGTTGTTTCTGGAATTG
ATCTCGCCAAAAAGGACATCTTTGGAGCCAGTGATCCGTATGTGAAACTTTCATTGTACGTAGCGGATGAGAATAGAGAACTTGCTTTGG
TCCAGACAAAAACAATTAAAAAGACACTGAACCCAAAATGGAATGAAGAATTTTATTTCAGGGTAAACCCATCTAATCACAGACTCCTAT
TTGAAGTATTTGACGAAAATAGACTGGTGGTGTTTGAGAAGGGCGGAGTGTACCTGCACACCAGCGCTAAGAAGTATCAGGACCGAGACT
CTCTCATCGCTGGTGTCATCCGTGTCGTGGAAAAGGACAATGACGTCCTCCTGCACTGGGCTCCTGTAGAGGAGGCTGGAGATTCCACCC
AAATCCTCTTCTCCAAGAAGGACTCCAGTGGGGGTGACTCATGTGCTTCTGAGGAGGAACCAACCTTTGACCCCGACTATGAACCTGACT
GGGCTGTCATCAGCACTGTGCGGCCACAGCTCTGCCACTCAGAGCCCACGAGAGGTGCAGAGCCCAGCTGCCCCCAGGGCTCCTGGGCCT
TCTCAGTGAGTCTGGGGGAGCTAAAGTCCATCCGCCGCTCCAAGCCAGGCCTCAGCTGGGCCTACCTGGTTCTGGTGACCCAGGCTGGAG
GTTCCCTGCCCGCACTGCACTTCCACCGCGGGGGCACCCGCGCCCTGCTCCGCGTCCTCAGCCGCTACCTGCTGTTGGCCAGCTCCCCGC
AGGACTCCCGCCTCTACCTTGTCTTCCCCCACGACTCCTCTGCTCTCTCCAACTCCTTCCACCACCTGCAGCTCTTTGACCAGGACAGCT
CCAATGTGGTGTCACGCTTCCTCCAGGATCCCTACTCCACCACCTTCAGCAGCTTCTCCCGAGTGACCAACTTCTTCCGGGGTGCCCTGC
AGCCACAGCCTGAGGGAGCCGCCTCCGACCTTCCCCCGCCACCCGACGATGAGCCCGAGCCTGGATTCGAGGTCATTTCCTGTGTGGAGC
TGGGGCCTCGGCCAACCGTGGAGCGGGGCCCTCCAGTTACAGAGGAGGAGTGGGCACGCCACGTGGGCCCTGAAGGTCGCCTGCAGCAGG
TCCCTGAGCTGAAGAACCGGATCTTCTCGGGGGGTCTGAGCCCCAGCCTGCGGCGCGAGGCCTGGAAGTTCCTCCTAGGGTACCTCAGCT
GGGAAGGCACAGCTGAGGAGCACAAGGCCCACATACGCAAGAAAACGGATGAGTATTTCCGCATGAAGCTGCAGTGGAAATCTGTGAGCC
CTGAGCAGGAGCGGAGAAACTCACTTCTGCATGGATACCGCAGCCTCATCGAAAGGGATGTGAGCCGCACTGACAGGACCAACAAGTTCT
ACGAGGGTCCCGAGAACCCGGGGCTGGGCCTGCTGAACGATATCCTCCTCACCTACTGCATGTATCACTTCGACCTCGGCTACGTCCAGG
GCATGAGTGATCTTCTCTCCCCGATCCTCTACGTCATTCAGAACGAGGTGGATGCTTTCTGGTGTTTCTGTGGCTTCATGGAGCTCGTGC
AAGGGAACTTTGAAGAGAGCCAGGAGACCATGAAGCGGCAACTCGGGCGACTGCTGCTGCTCCTGAGGGTGCTGGACCCCCTGCTCTGCG
ACTTCCTGGATTCCCAGGACTCCGGCTCTCTCTGCTTCTGTTTCCGGTGGCTGCTCATCTGGTTCAAGAGGGAATTCCCCTTCCCGGATG
TCCTTCGGCTGTGGGAGGTGCTGTGGACAGGGCTCCCTGGCCCCAATCTGCACCTGCTGGTGGCCTGCGCCATCCTGGACATGGAGAGGG
ACACCCTCATGCTGTCCGGCTTCGGCTCCAATGAGATCCTCAAGCACATCAACGAGCTGACTATGAAGCTGAGCGTGGAGGACGTGCTGA
CCCGCGCCGAGGCCCTGCACCGCCAGCTAACCGCCTGCCCCGAGCTGCCCCACAACGTGCAGGAGATCCTGGGGCTGGCCCCGCCCGCAG
AGCCCCACAGCCCCTCGCCCACCGCCTCCCCGCTGCCTCTGTCGCCCACCCGGGCCCCGCCCACCCCGCCGCCCTCCACGGACACAGCCC
CGCAGCCCGACAGCAGCCTGGAGATCCTGCCCGAGGAGGAGGACGAGGGCGCCGACTCCTAACCCCGCCAGGCAGCCTCGTTCTGCACAG
GCACTTTAGCCCGAGCCAGGCACACCTGCGAGGGGGCAGGTGTGCTCCGCCGCCCTGCTGATAAGCTGGCTTCATTAAACTGACACTTCT

>58431_58431_7_NEDD4L-TBC1D17_NEDD4L_chr18_55919286_ENST00000357895_TBC1D17_chr19_50381400_ENST00000221543_length(amino acids)=732AA_BP=91
MRRLAFEQGESRILRVKVVSGIDLAKKDIFGASDPYVKLSLYVADENRELALVQTKTIKKTLNPKWNEEFYFRVNPSNHRLLFEVFDENR
LVVFEKGGVYLHTSAKKYQDRDSLIAGVIRVVEKDNDVLLHWAPVEEAGDSTQILFSKKDSSGGDSCASEEEPTFDPDYEPDWAVISTVR
PQLCHSEPTRGAEPSCPQGSWAFSVSLGELKSIRRSKPGLSWAYLVLVTQAGGSLPALHFHRGGTRALLRVLSRYLLLASSPQDSRLYLV
FPHDSSALSNSFHHLQLFDQDSSNVVSRFLQDPYSTTFSSFSRVTNFFRGALQPQPEGAASDLPPPPDDEPEPGFEVISCVELGPRPTVE
RGPPVTEEEWARHVGPEGRLQQVPELKNRIFSGGLSPSLRREAWKFLLGYLSWEGTAEEHKAHIRKKTDEYFRMKLQWKSVSPEQERRNS
LLHGYRSLIERDVSRTDRTNKFYEGPENPGLGLLNDILLTYCMYHFDLGYVQGMSDLLSPILYVIQNEVDAFWCFCGFMELVQGNFEESQ
ETMKRQLGRLLLLLRVLDPLLCDFLDSQDSGSLCFCFRWLLIWFKREFPFPDVLRLWEVLWTGLPGPNLHLLVACAILDMERDTLMLSGF
GSNEILKHINELTMKLSVEDVLTRAEALHRQLTACPELPHNVQEILGLAPPAEPHSPSPTASPLPLSPTRAPPTPPPSTDTAPQPDSSLE

--------------------------------------------------------------
>58431_58431_8_NEDD4L-TBC1D17_NEDD4L_chr18_55919286_ENST00000357895_TBC1D17_chr19_50381755_ENST00000221543_length(transcript)=2423nt_BP=476nt
GCCATTTCCAGAGAGGAACAACCGTGTAGACTGCTTTCCTGGGAGTCAAGTTAAAACTTCTCTCCTGTGACCTTGTCACCCGGCAGTGGA
AAGTTACCCTTGGCTGCAGCCACGACTTCCGCATACTCTTCAGAACTTGCTCTGCCCTTGAGTTTTCCAGCTTTCCTTTAATGCACTAAA
CCTTTAATATTGTATTCTCCTAAATGAGACGTCTCGCATTTGAGCAGGGAGAGTCCCGTATTCTCAGAGTAAAAGTTGTTTCTGGAATTG
ATCTCGCCAAAAAGGACATCTTTGGAGCCAGTGATCCGTATGTGAAACTTTCATTGTACGTAGCGGATGAGAATAGAGAACTTGCTTTGG
TCCAGACAAAAACAATTAAAAAGACACTGAACCCAAAATGGAATGAAGAATTTTATTTCAGGGTAAACCCATCTAATCACAGACTCCTAT
TTGAAGTATTTGACGAAAATAGACTGGACAATGACGTCCTCCTGCACTGGGCTCCTGTAGAGGAGGCTGGAGATTCCACCCAAATCCTCT
TCTCCAAGAAGGACTCCAGTGGGGGTGACTCATGTGCTTCTGAGGAGGAACCAACCTTTGACCCCGACTATGAACCTGACTGGGCTGTCA
TCAGCACTGTGCGGCCACAGCTCTGCCACTCAGAGCCCACGAGAGGTGCAGAGCCCAGCTGCCCCCAGGGCTCCTGGGCCTTCTCAGTGA
GTCTGGGGGAGCTAAAGTCCATCCGCCGCTCCAAGCCAGGCCTCAGCTGGGCCTACCTGGTTCTGGTGACCCAGGCTGGAGGTTCCCTGC
CCGCACTGCACTTCCACCGCGGGGGCACCCGCGCCCTGCTCCGCGTCCTCAGCCGCTACCTGCTGTTGGCCAGCTCCCCGCAGGACTCCC
GCCTCTACCTTGTCTTCCCCCACGACTCCTCTGCTCTCTCCAACTCCTTCCACCACCTGCAGCTCTTTGACCAGGACAGCTCCAATGTGG
TGTCACGCTTCCTCCAGGATCCCTACTCCACCACCTTCAGCAGCTTCTCCCGAGTGACCAACTTCTTCCGGGGTGCCCTGCAGCCACAGC
CTGAGGGAGCCGCCTCCGACCTTCCCCCGCCACCCGACGATGAGCCCGAGCCTGGATTCGAGGTCATTTCCTGTGTGGAGCTGGGGCCTC
GGCCAACCGTGGAGCGGGGCCCTCCAGTTACAGAGGAGGAGTGGGCACGCCACGTGGGCCCTGAAGGTCGCCTGCAGCAGGTCCCTGAGC
TGAAGAACCGGATCTTCTCGGGGGGTCTGAGCCCCAGCCTGCGGCGCGAGGCCTGGAAGTTCCTCCTAGGGTACCTCAGCTGGGAAGGCA
CAGCTGAGGAGCACAAGGCCCACATACGCAAGAAAACGGATGAGTATTTCCGCATGAAGCTGCAGTGGAAATCTGTGAGCCCTGAGCAGG
AGCGGAGAAACTCACTTCTGCATGGATACCGCAGCCTCATCGAAAGGGATGTGAGCCGCACTGACAGGACCAACAAGTTCTACGAGGGTC
CCGAGAACCCGGGGCTGGGCCTGCTGAACGATATCCTCCTCACCTACTGCATGTATCACTTCGACCTCGGCTACGTCCAGGGCATGAGTG
ATCTTCTCTCCCCGATCCTCTACGTCATTCAGAACGAGGTGGATGCTTTCTGGTGTTTCTGTGGCTTCATGGAGCTCGTGCAAGGGAACT
TTGAAGAGAGCCAGGAGACCATGAAGCGGCAACTCGGGCGACTGCTGCTGCTCCTGAGGGTGCTGGACCCCCTGCTCTGCGACTTCCTGG
ATTCCCAGGACTCCGGCTCTCTCTGCTTCTGTTTCCGGTGGCTGCTCATCTGGTTCAAGAGGGAATTCCCCTTCCCGGATGTCCTTCGGC
TGTGGGAGGTGCTGTGGACAGGGCTCCCTGGCCCCAATCTGCACCTGCTGGTGGCCTGCGCCATCCTGGACATGGAGAGGGACACCCTCA
TGCTGTCCGGCTTCGGCTCCAATGAGATCCTCAAGCACATCAACGAGCTGACTATGAAGCTGAGCGTGGAGGACGTGCTGACCCGCGCCG
AGGCCCTGCACCGCCAGCTAACCGCCTGCCCCGAGCTGCCCCACAACGTGCAGGAGATCCTGGGGCTGGCCCCGCCCGCAGAGCCCCACA
GCCCCTCGCCCACCGCCTCCCCGCTGCCTCTGTCGCCCACCCGGGCCCCGCCCACCCCGCCGCCCTCCACGGACACAGCCCCGCAGCCCG
ACAGCAGCCTGGAGATCCTGCCCGAGGAGGAGGACGAGGGCGCCGACTCCTAACCCCGCCAGGCAGCCTCGTTCTGCACAGGCACTTTAG

>58431_58431_8_NEDD4L-TBC1D17_NEDD4L_chr18_55919286_ENST00000357895_TBC1D17_chr19_50381755_ENST00000221543_length(amino acids)=699AA_BP=91
MRRLAFEQGESRILRVKVVSGIDLAKKDIFGASDPYVKLSLYVADENRELALVQTKTIKKTLNPKWNEEFYFRVNPSNHRLLFEVFDENR
LDNDVLLHWAPVEEAGDSTQILFSKKDSSGGDSCASEEEPTFDPDYEPDWAVISTVRPQLCHSEPTRGAEPSCPQGSWAFSVSLGELKSI
RRSKPGLSWAYLVLVTQAGGSLPALHFHRGGTRALLRVLSRYLLLASSPQDSRLYLVFPHDSSALSNSFHHLQLFDQDSSNVVSRFLQDP
YSTTFSSFSRVTNFFRGALQPQPEGAASDLPPPPDDEPEPGFEVISCVELGPRPTVERGPPVTEEEWARHVGPEGRLQQVPELKNRIFSG
GLSPSLRREAWKFLLGYLSWEGTAEEHKAHIRKKTDEYFRMKLQWKSVSPEQERRNSLLHGYRSLIERDVSRTDRTNKFYEGPENPGLGL
LNDILLTYCMYHFDLGYVQGMSDLLSPILYVIQNEVDAFWCFCGFMELVQGNFEESQETMKRQLGRLLLLLRVLDPLLCDFLDSQDSGSL
CFCFRWLLIWFKREFPFPDVLRLWEVLWTGLPGPNLHLLVACAILDMERDTLMLSGFGSNEILKHINELTMKLSVEDVLTRAEALHRQLT

--------------------------------------------------------------
>58431_58431_9_NEDD4L-TBC1D17_NEDD4L_chr18_55919286_ENST00000357895_TBC1D17_chr19_50381755_ENST00000535102_length(transcript)=2422nt_BP=476nt
GCCATTTCCAGAGAGGAACAACCGTGTAGACTGCTTTCCTGGGAGTCAAGTTAAAACTTCTCTCCTGTGACCTTGTCACCCGGCAGTGGA
AAGTTACCCTTGGCTGCAGCCACGACTTCCGCATACTCTTCAGAACTTGCTCTGCCCTTGAGTTTTCCAGCTTTCCTTTAATGCACTAAA
CCTTTAATATTGTATTCTCCTAAATGAGACGTCTCGCATTTGAGCAGGGAGAGTCCCGTATTCTCAGAGTAAAAGTTGTTTCTGGAATTG
ATCTCGCCAAAAAGGACATCTTTGGAGCCAGTGATCCGTATGTGAAACTTTCATTGTACGTAGCGGATGAGAATAGAGAACTTGCTTTGG
TCCAGACAAAAACAATTAAAAAGACACTGAACCCAAAATGGAATGAAGAATTTTATTTCAGGGTAAACCCATCTAATCACAGACTCCTAT
TTGAAGTATTTGACGAAAATAGACTGGACAATGACGTCCTCCTGCACTGGGCTCCTGTAGAGGAGGCTGGAGATTCCACCCAAATCCTCT
TCTCCAAGAAGGACTCCAGTGGGGGTGACTCATGTGCTTCTGAGGAGGAACCAACCTTTGACCCCGACTATGAACCTGACTGGGCTGTCA
TCAGCACTGTGCGGCCACAGCTCTGCCACTCAGAGCCCACGAGAGGTGCAGAGCCCAGCTGCCCCCAGGGCTCCTGGGCCTTCTCAGTGA
GTCTGGGGGAGCTAAAGTCCATCCGCCGCTCCAAGCCAGGCCTCAGCTGGGCCTACCTGGTTCTGGTGACCCAGGCTGGAGGTTCCCTGC
CCGCACTGCACTTCCACCGCGGGGGCACCCGCGCCCTGCTCCGCGTCCTCAGCCGCTACCTGCTGTTGGCCAGCTCCCCGCAGGACTCCC
GCCTCTACCTTGTCTTCCCCCACGACTCCTCTGCTCTCTCCAACTCCTTCCACCACCTGCAGCTCTTTGACCAGGACAGCTCCAATGTGG
TGTCACGCTTCCTCCAGGATCCCTACTCCACCACCTTCAGCAGCTTCTCCCGAGTGACCAACTTCTTCCGGGGTGCCCTGCAGCCACAGC
CTGAGGGAGCCGCCTCCGACCTTCCCCCGCCACCCGACGATGAGCCCGAGCCTGGATTCGAGGTCATTTCCTGTGTGGAGCTGGGGCCTC
GGCCAACCGTGGAGCGGGGCCCTCCAGTTACAGAGGAGGAGTGGGCACGCCACGTGGGCCCTGAAGGTCGCCTGCAGCAGGTCCCTGAGC
TGAAGAACCGGATCTTCTCGGGGGGTCTGAGCCCCAGCCTGCGGCGCGAGGCCTGGAAGTTCCTCCTAGGGTACCTCAGCTGGGAAGGCA
CAGCTGAGGAGCACAAGGCCCACATACGCAAGAAAACGGATGAGTATTTCCGCATGAAGCTGCAGTGGAAATCTGTGAGCCCTGAGCAGG
AGCGGAGAAACTCACTTCTGCATGGATACCGCAGCCTCATCGAAAGGGATGTGAGCCGCACTGACAGGACCAACAAGTTCTACGAGGGTC
CCGAGAACCCGGGGCTGGGCCTGCTGAACGATATCCTCCTCACCTACTGCATGTATCACTTCGACCTCGGCTACGTCCAGGGCATGAGTG
ATCTTCTCTCCCCGATCCTCTACGTCATTCAGAACGAGGTGGATGCTTTCTGGTGTTTCTGTGGCTTCATGGAGCTCGTGCAAGGGAACT
TTGAAGAGAGCCAGGAGACCATGAAGCGGCAACTCGGGCGACTGCTGCTGCTCCTGAGGGTGCTGGACCCCCTGCTCTGCGACTTCCTGG
ATTCCCAGGACTCCGGCTCTCTCTGCTTCTGTTTCCGGTGGCTGCTCATCTGGTTCAAGAGGGAATTCCCCTTCCCGGATGTCCTTCGGC
TGTGGGAGGTGCTGTGGACAGGGCTCCCTGGCCCCAATCTGCACCTGCTGGTGGCCTGCGCCATCCTGGACATGGAGAGGGACACCCTCA
TGCTGTCCGGCTTCGGCTCCAATGAGATCCTCAAGCACATCAACGAGCTGACTATGAAGCTGAGCGTGGAGGACGTGCTGACCCGCGCCG
AGGCCCTGCACCGCCAGCTAACCGCCTGCCCCGAGCTGCCCCACAACGTGCAGGAGATCCTGGGGCTGGCCCCGCCCGCAGAGCCCCACA
GCCCCTCGCCCACCGCCTCCCCGCTGCCTCTGTCGCCCACCCGGGCCCCGCCCACCCCGCCGCCCTCCACGGACACAGCCCCGCAGCCCG
ACAGCAGCCTGGAGATCCTGCCCGAGGAGGAGGACGAGGGCGCCGACTCCTAACCCCGCCAGGCAGCCTCGTTCTGCACAGGCACTTTAG

>58431_58431_9_NEDD4L-TBC1D17_NEDD4L_chr18_55919286_ENST00000357895_TBC1D17_chr19_50381755_ENST00000535102_length(amino acids)=699AA_BP=91
MRRLAFEQGESRILRVKVVSGIDLAKKDIFGASDPYVKLSLYVADENRELALVQTKTIKKTLNPKWNEEFYFRVNPSNHRLLFEVFDENR
LDNDVLLHWAPVEEAGDSTQILFSKKDSSGGDSCASEEEPTFDPDYEPDWAVISTVRPQLCHSEPTRGAEPSCPQGSWAFSVSLGELKSI
RRSKPGLSWAYLVLVTQAGGSLPALHFHRGGTRALLRVLSRYLLLASSPQDSRLYLVFPHDSSALSNSFHHLQLFDQDSSNVVSRFLQDP
YSTTFSSFSRVTNFFRGALQPQPEGAASDLPPPPDDEPEPGFEVISCVELGPRPTVERGPPVTEEEWARHVGPEGRLQQVPELKNRIFSG
GLSPSLRREAWKFLLGYLSWEGTAEEHKAHIRKKTDEYFRMKLQWKSVSPEQERRNSLLHGYRSLIERDVSRTDRTNKFYEGPENPGLGL
LNDILLTYCMYHFDLGYVQGMSDLLSPILYVIQNEVDAFWCFCGFMELVQGNFEESQETMKRQLGRLLLLLRVLDPLLCDFLDSQDSGSL
CFCFRWLLIWFKREFPFPDVLRLWEVLWTGLPGPNLHLLVACAILDMERDTLMLSGFGSNEILKHINELTMKLSVEDVLTRAEALHRQLT

--------------------------------------------------------------
>58431_58431_10_NEDD4L-TBC1D17_NEDD4L_chr18_55919286_ENST00000382850_TBC1D17_chr19_50381400_ENST00000221543_length(transcript)=2456nt_BP=410nt
CGCAGGGTAGGGTGCGGGACCGGGGGGACCTGGAGGCAGAGGGGAGAACCGGCCGTCCGCGCCGCAGCACAGCCGCTGGGAGCGCCTCAG
ACCCCGCGCGGGGCGCCGGCTCCATGGCGACCGGGCTCGGGGAGCCGGTCTATGGACTTTCCGAAGACGAGGGAGAGTCCCGTATTCTCA
GAGTAAAAGTTGTTTCTGGAATTGATCTCGCCAAAAAGGACATCTTTGGAGCCAGTGATCCGTATGTGAAACTTTCATTGTACGTAGCGG
ATGAGAATAGAGAACTTGCTTTGGTCCAGACAAAAACAATTAAAAAGACACTGAACCCAAAATGGAATGAAGAATTTTATTTCAGGGTAA
ACCCATCTAATCACAGACTCCTATTTGAAGTATTTGACGAAAATAGACTGGTGGTGTTTGAGAAGGGCGGAGTGTACCTGCACACCAGCG
CTAAGAAGTATCAGGACCGAGACTCTCTCATCGCTGGTGTCATCCGTGTCGTGGAAAAGGACAATGACGTCCTCCTGCACTGGGCTCCTG
TAGAGGAGGCTGGAGATTCCACCCAAATCCTCTTCTCCAAGAAGGACTCCAGTGGGGGTGACTCATGTGCTTCTGAGGAGGAACCAACCT
TTGACCCCGACTATGAACCTGACTGGGCTGTCATCAGCACTGTGCGGCCACAGCTCTGCCACTCAGAGCCCACGAGAGGTGCAGAGCCCA
GCTGCCCCCAGGGCTCCTGGGCCTTCTCAGTGAGTCTGGGGGAGCTAAAGTCCATCCGCCGCTCCAAGCCAGGCCTCAGCTGGGCCTACC
TGGTTCTGGTGACCCAGGCTGGAGGTTCCCTGCCCGCACTGCACTTCCACCGCGGGGGCACCCGCGCCCTGCTCCGCGTCCTCAGCCGCT
ACCTGCTGTTGGCCAGCTCCCCGCAGGACTCCCGCCTCTACCTTGTCTTCCCCCACGACTCCTCTGCTCTCTCCAACTCCTTCCACCACC
TGCAGCTCTTTGACCAGGACAGCTCCAATGTGGTGTCACGCTTCCTCCAGGATCCCTACTCCACCACCTTCAGCAGCTTCTCCCGAGTGA
CCAACTTCTTCCGGGGTGCCCTGCAGCCACAGCCTGAGGGAGCCGCCTCCGACCTTCCCCCGCCACCCGACGATGAGCCCGAGCCTGGAT
TCGAGGTCATTTCCTGTGTGGAGCTGGGGCCTCGGCCAACCGTGGAGCGGGGCCCTCCAGTTACAGAGGAGGAGTGGGCACGCCACGTGG
GCCCTGAAGGTCGCCTGCAGCAGGTCCCTGAGCTGAAGAACCGGATCTTCTCGGGGGGTCTGAGCCCCAGCCTGCGGCGCGAGGCCTGGA
AGTTCCTCCTAGGGTACCTCAGCTGGGAAGGCACAGCTGAGGAGCACAAGGCCCACATACGCAAGAAAACGGATGAGTATTTCCGCATGA
AGCTGCAGTGGAAATCTGTGAGCCCTGAGCAGGAGCGGAGAAACTCACTTCTGCATGGATACCGCAGCCTCATCGAAAGGGATGTGAGCC
GCACTGACAGGACCAACAAGTTCTACGAGGGTCCCGAGAACCCGGGGCTGGGCCTGCTGAACGATATCCTCCTCACCTACTGCATGTATC
ACTTCGACCTCGGCTACGTCCAGGGCATGAGTGATCTTCTCTCCCCGATCCTCTACGTCATTCAGAACGAGGTGGATGCTTTCTGGTGTT
TCTGTGGCTTCATGGAGCTCGTGCAAGGGAACTTTGAAGAGAGCCAGGAGACCATGAAGCGGCAACTCGGGCGACTGCTGCTGCTCCTGA
GGGTGCTGGACCCCCTGCTCTGCGACTTCCTGGATTCCCAGGACTCCGGCTCTCTCTGCTTCTGTTTCCGGTGGCTGCTCATCTGGTTCA
AGAGGGAATTCCCCTTCCCGGATGTCCTTCGGCTGTGGGAGGTGCTGTGGACAGGGCTCCCTGGCCCCAATCTGCACCTGCTGGTGGCCT
GCGCCATCCTGGACATGGAGAGGGACACCCTCATGCTGTCCGGCTTCGGCTCCAATGAGATCCTCAAGCACATCAACGAGCTGACTATGA
AGCTGAGCGTGGAGGACGTGCTGACCCGCGCCGAGGCCCTGCACCGCCAGCTAACCGCCTGCCCCGAGCTGCCCCACAACGTGCAGGAGA
TCCTGGGGCTGGCCCCGCCCGCAGAGCCCCACAGCCCCTCGCCCACCGCCTCCCCGCTGCCTCTGTCGCCCACCCGGGCCCCGCCCACCC
CGCCGCCCTCCACGGACACAGCCCCGCAGCCCGACAGCAGCCTGGAGATCCTGCCCGAGGAGGAGGACGAGGGCGCCGACTCCTAACCCC
GCCAGGCAGCCTCGTTCTGCACAGGCACTTTAGCCCGAGCCAGGCACACCTGCGAGGGGGCAGGTGTGCTCCGCCGCCCTGCTGATAAGC

>58431_58431_10_NEDD4L-TBC1D17_NEDD4L_chr18_55919286_ENST00000382850_TBC1D17_chr19_50381400_ENST00000221543_length(amino acids)=768AA_BP=127
MEAEGRTGRPRRSTAAGSASDPARGAGSMATGLGEPVYGLSEDEGESRILRVKVVSGIDLAKKDIFGASDPYVKLSLYVADENRELALVQ
TKTIKKTLNPKWNEEFYFRVNPSNHRLLFEVFDENRLVVFEKGGVYLHTSAKKYQDRDSLIAGVIRVVEKDNDVLLHWAPVEEAGDSTQI
LFSKKDSSGGDSCASEEEPTFDPDYEPDWAVISTVRPQLCHSEPTRGAEPSCPQGSWAFSVSLGELKSIRRSKPGLSWAYLVLVTQAGGS
LPALHFHRGGTRALLRVLSRYLLLASSPQDSRLYLVFPHDSSALSNSFHHLQLFDQDSSNVVSRFLQDPYSTTFSSFSRVTNFFRGALQP
QPEGAASDLPPPPDDEPEPGFEVISCVELGPRPTVERGPPVTEEEWARHVGPEGRLQQVPELKNRIFSGGLSPSLRREAWKFLLGYLSWE
GTAEEHKAHIRKKTDEYFRMKLQWKSVSPEQERRNSLLHGYRSLIERDVSRTDRTNKFYEGPENPGLGLLNDILLTYCMYHFDLGYVQGM
SDLLSPILYVIQNEVDAFWCFCGFMELVQGNFEESQETMKRQLGRLLLLLRVLDPLLCDFLDSQDSGSLCFCFRWLLIWFKREFPFPDVL
RLWEVLWTGLPGPNLHLLVACAILDMERDTLMLSGFGSNEILKHINELTMKLSVEDVLTRAEALHRQLTACPELPHNVQEILGLAPPAEP

--------------------------------------------------------------
>58431_58431_11_NEDD4L-TBC1D17_NEDD4L_chr18_55919286_ENST00000382850_TBC1D17_chr19_50381755_ENST00000221543_length(transcript)=2357nt_BP=410nt
CGCAGGGTAGGGTGCGGGACCGGGGGGACCTGGAGGCAGAGGGGAGAACCGGCCGTCCGCGCCGCAGCACAGCCGCTGGGAGCGCCTCAG
ACCCCGCGCGGGGCGCCGGCTCCATGGCGACCGGGCTCGGGGAGCCGGTCTATGGACTTTCCGAAGACGAGGGAGAGTCCCGTATTCTCA
GAGTAAAAGTTGTTTCTGGAATTGATCTCGCCAAAAAGGACATCTTTGGAGCCAGTGATCCGTATGTGAAACTTTCATTGTACGTAGCGG
ATGAGAATAGAGAACTTGCTTTGGTCCAGACAAAAACAATTAAAAAGACACTGAACCCAAAATGGAATGAAGAATTTTATTTCAGGGTAA
ACCCATCTAATCACAGACTCCTATTTGAAGTATTTGACGAAAATAGACTGGACAATGACGTCCTCCTGCACTGGGCTCCTGTAGAGGAGG
CTGGAGATTCCACCCAAATCCTCTTCTCCAAGAAGGACTCCAGTGGGGGTGACTCATGTGCTTCTGAGGAGGAACCAACCTTTGACCCCG
ACTATGAACCTGACTGGGCTGTCATCAGCACTGTGCGGCCACAGCTCTGCCACTCAGAGCCCACGAGAGGTGCAGAGCCCAGCTGCCCCC
AGGGCTCCTGGGCCTTCTCAGTGAGTCTGGGGGAGCTAAAGTCCATCCGCCGCTCCAAGCCAGGCCTCAGCTGGGCCTACCTGGTTCTGG
TGACCCAGGCTGGAGGTTCCCTGCCCGCACTGCACTTCCACCGCGGGGGCACCCGCGCCCTGCTCCGCGTCCTCAGCCGCTACCTGCTGT
TGGCCAGCTCCCCGCAGGACTCCCGCCTCTACCTTGTCTTCCCCCACGACTCCTCTGCTCTCTCCAACTCCTTCCACCACCTGCAGCTCT
TTGACCAGGACAGCTCCAATGTGGTGTCACGCTTCCTCCAGGATCCCTACTCCACCACCTTCAGCAGCTTCTCCCGAGTGACCAACTTCT
TCCGGGGTGCCCTGCAGCCACAGCCTGAGGGAGCCGCCTCCGACCTTCCCCCGCCACCCGACGATGAGCCCGAGCCTGGATTCGAGGTCA
TTTCCTGTGTGGAGCTGGGGCCTCGGCCAACCGTGGAGCGGGGCCCTCCAGTTACAGAGGAGGAGTGGGCACGCCACGTGGGCCCTGAAG
GTCGCCTGCAGCAGGTCCCTGAGCTGAAGAACCGGATCTTCTCGGGGGGTCTGAGCCCCAGCCTGCGGCGCGAGGCCTGGAAGTTCCTCC
TAGGGTACCTCAGCTGGGAAGGCACAGCTGAGGAGCACAAGGCCCACATACGCAAGAAAACGGATGAGTATTTCCGCATGAAGCTGCAGT
GGAAATCTGTGAGCCCTGAGCAGGAGCGGAGAAACTCACTTCTGCATGGATACCGCAGCCTCATCGAAAGGGATGTGAGCCGCACTGACA
GGACCAACAAGTTCTACGAGGGTCCCGAGAACCCGGGGCTGGGCCTGCTGAACGATATCCTCCTCACCTACTGCATGTATCACTTCGACC
TCGGCTACGTCCAGGGCATGAGTGATCTTCTCTCCCCGATCCTCTACGTCATTCAGAACGAGGTGGATGCTTTCTGGTGTTTCTGTGGCT
TCATGGAGCTCGTGCAAGGGAACTTTGAAGAGAGCCAGGAGACCATGAAGCGGCAACTCGGGCGACTGCTGCTGCTCCTGAGGGTGCTGG
ACCCCCTGCTCTGCGACTTCCTGGATTCCCAGGACTCCGGCTCTCTCTGCTTCTGTTTCCGGTGGCTGCTCATCTGGTTCAAGAGGGAAT
TCCCCTTCCCGGATGTCCTTCGGCTGTGGGAGGTGCTGTGGACAGGGCTCCCTGGCCCCAATCTGCACCTGCTGGTGGCCTGCGCCATCC
TGGACATGGAGAGGGACACCCTCATGCTGTCCGGCTTCGGCTCCAATGAGATCCTCAAGCACATCAACGAGCTGACTATGAAGCTGAGCG
TGGAGGACGTGCTGACCCGCGCCGAGGCCCTGCACCGCCAGCTAACCGCCTGCCCCGAGCTGCCCCACAACGTGCAGGAGATCCTGGGGC
TGGCCCCGCCCGCAGAGCCCCACAGCCCCTCGCCCACCGCCTCCCCGCTGCCTCTGTCGCCCACCCGGGCCCCGCCCACCCCGCCGCCCT
CCACGGACACAGCCCCGCAGCCCGACAGCAGCCTGGAGATCCTGCCCGAGGAGGAGGACGAGGGCGCCGACTCCTAACCCCGCCAGGCAG
CCTCGTTCTGCACAGGCACTTTAGCCCGAGCCAGGCACACCTGCGAGGGGGCAGGTGTGCTCCGCCGCCCTGCTGATAAGCTGGCTTCAT

>58431_58431_11_NEDD4L-TBC1D17_NEDD4L_chr18_55919286_ENST00000382850_TBC1D17_chr19_50381755_ENST00000221543_length(amino acids)=735AA_BP=127
MEAEGRTGRPRRSTAAGSASDPARGAGSMATGLGEPVYGLSEDEGESRILRVKVVSGIDLAKKDIFGASDPYVKLSLYVADENRELALVQ
TKTIKKTLNPKWNEEFYFRVNPSNHRLLFEVFDENRLDNDVLLHWAPVEEAGDSTQILFSKKDSSGGDSCASEEEPTFDPDYEPDWAVIS
TVRPQLCHSEPTRGAEPSCPQGSWAFSVSLGELKSIRRSKPGLSWAYLVLVTQAGGSLPALHFHRGGTRALLRVLSRYLLLASSPQDSRL
YLVFPHDSSALSNSFHHLQLFDQDSSNVVSRFLQDPYSTTFSSFSRVTNFFRGALQPQPEGAASDLPPPPDDEPEPGFEVISCVELGPRP
TVERGPPVTEEEWARHVGPEGRLQQVPELKNRIFSGGLSPSLRREAWKFLLGYLSWEGTAEEHKAHIRKKTDEYFRMKLQWKSVSPEQER
RNSLLHGYRSLIERDVSRTDRTNKFYEGPENPGLGLLNDILLTYCMYHFDLGYVQGMSDLLSPILYVIQNEVDAFWCFCGFMELVQGNFE
ESQETMKRQLGRLLLLLRVLDPLLCDFLDSQDSGSLCFCFRWLLIWFKREFPFPDVLRLWEVLWTGLPGPNLHLLVACAILDMERDTLML
SGFGSNEILKHINELTMKLSVEDVLTRAEALHRQLTACPELPHNVQEILGLAPPAEPHSPSPTASPLPLSPTRAPPTPPPSTDTAPQPDS

--------------------------------------------------------------
>58431_58431_12_NEDD4L-TBC1D17_NEDD4L_chr18_55919286_ENST00000382850_TBC1D17_chr19_50381755_ENST00000535102_length(transcript)=2356nt_BP=410nt
CGCAGGGTAGGGTGCGGGACCGGGGGGACCTGGAGGCAGAGGGGAGAACCGGCCGTCCGCGCCGCAGCACAGCCGCTGGGAGCGCCTCAG
ACCCCGCGCGGGGCGCCGGCTCCATGGCGACCGGGCTCGGGGAGCCGGTCTATGGACTTTCCGAAGACGAGGGAGAGTCCCGTATTCTCA
GAGTAAAAGTTGTTTCTGGAATTGATCTCGCCAAAAAGGACATCTTTGGAGCCAGTGATCCGTATGTGAAACTTTCATTGTACGTAGCGG
ATGAGAATAGAGAACTTGCTTTGGTCCAGACAAAAACAATTAAAAAGACACTGAACCCAAAATGGAATGAAGAATTTTATTTCAGGGTAA
ACCCATCTAATCACAGACTCCTATTTGAAGTATTTGACGAAAATAGACTGGACAATGACGTCCTCCTGCACTGGGCTCCTGTAGAGGAGG
CTGGAGATTCCACCCAAATCCTCTTCTCCAAGAAGGACTCCAGTGGGGGTGACTCATGTGCTTCTGAGGAGGAACCAACCTTTGACCCCG
ACTATGAACCTGACTGGGCTGTCATCAGCACTGTGCGGCCACAGCTCTGCCACTCAGAGCCCACGAGAGGTGCAGAGCCCAGCTGCCCCC
AGGGCTCCTGGGCCTTCTCAGTGAGTCTGGGGGAGCTAAAGTCCATCCGCCGCTCCAAGCCAGGCCTCAGCTGGGCCTACCTGGTTCTGG
TGACCCAGGCTGGAGGTTCCCTGCCCGCACTGCACTTCCACCGCGGGGGCACCCGCGCCCTGCTCCGCGTCCTCAGCCGCTACCTGCTGT
TGGCCAGCTCCCCGCAGGACTCCCGCCTCTACCTTGTCTTCCCCCACGACTCCTCTGCTCTCTCCAACTCCTTCCACCACCTGCAGCTCT
TTGACCAGGACAGCTCCAATGTGGTGTCACGCTTCCTCCAGGATCCCTACTCCACCACCTTCAGCAGCTTCTCCCGAGTGACCAACTTCT
TCCGGGGTGCCCTGCAGCCACAGCCTGAGGGAGCCGCCTCCGACCTTCCCCCGCCACCCGACGATGAGCCCGAGCCTGGATTCGAGGTCA
TTTCCTGTGTGGAGCTGGGGCCTCGGCCAACCGTGGAGCGGGGCCCTCCAGTTACAGAGGAGGAGTGGGCACGCCACGTGGGCCCTGAAG
GTCGCCTGCAGCAGGTCCCTGAGCTGAAGAACCGGATCTTCTCGGGGGGTCTGAGCCCCAGCCTGCGGCGCGAGGCCTGGAAGTTCCTCC
TAGGGTACCTCAGCTGGGAAGGCACAGCTGAGGAGCACAAGGCCCACATACGCAAGAAAACGGATGAGTATTTCCGCATGAAGCTGCAGT
GGAAATCTGTGAGCCCTGAGCAGGAGCGGAGAAACTCACTTCTGCATGGATACCGCAGCCTCATCGAAAGGGATGTGAGCCGCACTGACA
GGACCAACAAGTTCTACGAGGGTCCCGAGAACCCGGGGCTGGGCCTGCTGAACGATATCCTCCTCACCTACTGCATGTATCACTTCGACC
TCGGCTACGTCCAGGGCATGAGTGATCTTCTCTCCCCGATCCTCTACGTCATTCAGAACGAGGTGGATGCTTTCTGGTGTTTCTGTGGCT
TCATGGAGCTCGTGCAAGGGAACTTTGAAGAGAGCCAGGAGACCATGAAGCGGCAACTCGGGCGACTGCTGCTGCTCCTGAGGGTGCTGG
ACCCCCTGCTCTGCGACTTCCTGGATTCCCAGGACTCCGGCTCTCTCTGCTTCTGTTTCCGGTGGCTGCTCATCTGGTTCAAGAGGGAAT
TCCCCTTCCCGGATGTCCTTCGGCTGTGGGAGGTGCTGTGGACAGGGCTCCCTGGCCCCAATCTGCACCTGCTGGTGGCCTGCGCCATCC
TGGACATGGAGAGGGACACCCTCATGCTGTCCGGCTTCGGCTCCAATGAGATCCTCAAGCACATCAACGAGCTGACTATGAAGCTGAGCG
TGGAGGACGTGCTGACCCGCGCCGAGGCCCTGCACCGCCAGCTAACCGCCTGCCCCGAGCTGCCCCACAACGTGCAGGAGATCCTGGGGC
TGGCCCCGCCCGCAGAGCCCCACAGCCCCTCGCCCACCGCCTCCCCGCTGCCTCTGTCGCCCACCCGGGCCCCGCCCACCCCGCCGCCCT
CCACGGACACAGCCCCGCAGCCCGACAGCAGCCTGGAGATCCTGCCCGAGGAGGAGGACGAGGGCGCCGACTCCTAACCCCGCCAGGCAG
CCTCGTTCTGCACAGGCACTTTAGCCCGAGCCAGGCACACCTGCGAGGGGGCAGGTGTGCTCCGCCGCCCTGCTGATAAGCTGGCTTCAT

>58431_58431_12_NEDD4L-TBC1D17_NEDD4L_chr18_55919286_ENST00000382850_TBC1D17_chr19_50381755_ENST00000535102_length(amino acids)=735AA_BP=127
MEAEGRTGRPRRSTAAGSASDPARGAGSMATGLGEPVYGLSEDEGESRILRVKVVSGIDLAKKDIFGASDPYVKLSLYVADENRELALVQ
TKTIKKTLNPKWNEEFYFRVNPSNHRLLFEVFDENRLDNDVLLHWAPVEEAGDSTQILFSKKDSSGGDSCASEEEPTFDPDYEPDWAVIS
TVRPQLCHSEPTRGAEPSCPQGSWAFSVSLGELKSIRRSKPGLSWAYLVLVTQAGGSLPALHFHRGGTRALLRVLSRYLLLASSPQDSRL
YLVFPHDSSALSNSFHHLQLFDQDSSNVVSRFLQDPYSTTFSSFSRVTNFFRGALQPQPEGAASDLPPPPDDEPEPGFEVISCVELGPRP
TVERGPPVTEEEWARHVGPEGRLQQVPELKNRIFSGGLSPSLRREAWKFLLGYLSWEGTAEEHKAHIRKKTDEYFRMKLQWKSVSPEQER
RNSLLHGYRSLIERDVSRTDRTNKFYEGPENPGLGLLNDILLTYCMYHFDLGYVQGMSDLLSPILYVIQNEVDAFWCFCGFMELVQGNFE
ESQETMKRQLGRLLLLLRVLDPLLCDFLDSQDSGSLCFCFRWLLIWFKREFPFPDVLRLWEVLWTGLPGPNLHLLVACAILDMERDTLML
SGFGSNEILKHINELTMKLSVEDVLTRAEALHRQLTACPELPHNVQEILGLAPPAEPHSPSPTASPLPLSPTRAPPTPPPSTDTAPQPDS

--------------------------------------------------------------
>58431_58431_13_NEDD4L-TBC1D17_NEDD4L_chr18_55919286_ENST00000400345_TBC1D17_chr19_50381400_ENST00000221543_length(transcript)=2626nt_BP=580nt
GCGCGCAGTGAGAGGCGCCGGGGCTGCCGCCCGGTGCTCGGCGCGCTCTCGGGAGCCGCCCGCCCGCTGGTCCCGCAGCCTTCCGGGAGG
AAGCGGTGCCGGCAGCGTCCAGGGCGCGCTCTCGGGCACCCTCACCTGCCGGCGCCCGGCCGCTTACCCGGCAGGGCGTGCGCAGGGTAG
GGTGCGGGACCGGGGGGACCTGGAGGCAGAGGGGAGAACCGGCCGTCCGCGCCGCAGCACAGCCGCTGGGAGCGCCTCAGACCCCGCGCG
GGGCGCCGGCTCCATGGCGACCGGGCTCGGGGAGCCGGTCTATGGACTTTCCGAAGACGAGGGAGAGTCCCGTATTCTCAGAGTAAAAGT
TGTTTCTGGAATTGATCTCGCCAAAAAGGACATCTTTGGAGCCAGTGATCCGTATGTGAAACTTTCATTGTACGTAGCGGATGAGAATAG
AGAACTTGCTTTGGTCCAGACAAAAACAATTAAAAAGACACTGAACCCAAAATGGAATGAAGAATTTTATTTCAGGGTAAACCCATCTAA
TCACAGACTCCTATTTGAAGTATTTGACGAAAATAGACTGGTGGTGTTTGAGAAGGGCGGAGTGTACCTGCACACCAGCGCTAAGAAGTA
TCAGGACCGAGACTCTCTCATCGCTGGTGTCATCCGTGTCGTGGAAAAGGACAATGACGTCCTCCTGCACTGGGCTCCTGTAGAGGAGGC
TGGAGATTCCACCCAAATCCTCTTCTCCAAGAAGGACTCCAGTGGGGGTGACTCATGTGCTTCTGAGGAGGAACCAACCTTTGACCCCGA
CTATGAACCTGACTGGGCTGTCATCAGCACTGTGCGGCCACAGCTCTGCCACTCAGAGCCCACGAGAGGTGCAGAGCCCAGCTGCCCCCA
GGGCTCCTGGGCCTTCTCAGTGAGTCTGGGGGAGCTAAAGTCCATCCGCCGCTCCAAGCCAGGCCTCAGCTGGGCCTACCTGGTTCTGGT
GACCCAGGCTGGAGGTTCCCTGCCCGCACTGCACTTCCACCGCGGGGGCACCCGCGCCCTGCTCCGCGTCCTCAGCCGCTACCTGCTGTT
GGCCAGCTCCCCGCAGGACTCCCGCCTCTACCTTGTCTTCCCCCACGACTCCTCTGCTCTCTCCAACTCCTTCCACCACCTGCAGCTCTT
TGACCAGGACAGCTCCAATGTGGTGTCACGCTTCCTCCAGGATCCCTACTCCACCACCTTCAGCAGCTTCTCCCGAGTGACCAACTTCTT
CCGGGGTGCCCTGCAGCCACAGCCTGAGGGAGCCGCCTCCGACCTTCCCCCGCCACCCGACGATGAGCCCGAGCCTGGATTCGAGGTCAT
TTCCTGTGTGGAGCTGGGGCCTCGGCCAACCGTGGAGCGGGGCCCTCCAGTTACAGAGGAGGAGTGGGCACGCCACGTGGGCCCTGAAGG
TCGCCTGCAGCAGGTCCCTGAGCTGAAGAACCGGATCTTCTCGGGGGGTCTGAGCCCCAGCCTGCGGCGCGAGGCCTGGAAGTTCCTCCT
AGGGTACCTCAGCTGGGAAGGCACAGCTGAGGAGCACAAGGCCCACATACGCAAGAAAACGGATGAGTATTTCCGCATGAAGCTGCAGTG
GAAATCTGTGAGCCCTGAGCAGGAGCGGAGAAACTCACTTCTGCATGGATACCGCAGCCTCATCGAAAGGGATGTGAGCCGCACTGACAG
GACCAACAAGTTCTACGAGGGTCCCGAGAACCCGGGGCTGGGCCTGCTGAACGATATCCTCCTCACCTACTGCATGTATCACTTCGACCT
CGGCTACGTCCAGGGCATGAGTGATCTTCTCTCCCCGATCCTCTACGTCATTCAGAACGAGGTGGATGCTTTCTGGTGTTTCTGTGGCTT
CATGGAGCTCGTGCAAGGGAACTTTGAAGAGAGCCAGGAGACCATGAAGCGGCAACTCGGGCGACTGCTGCTGCTCCTGAGGGTGCTGGA
CCCCCTGCTCTGCGACTTCCTGGATTCCCAGGACTCCGGCTCTCTCTGCTTCTGTTTCCGGTGGCTGCTCATCTGGTTCAAGAGGGAATT
CCCCTTCCCGGATGTCCTTCGGCTGTGGGAGGTGCTGTGGACAGGGCTCCCTGGCCCCAATCTGCACCTGCTGGTGGCCTGCGCCATCCT
GGACATGGAGAGGGACACCCTCATGCTGTCCGGCTTCGGCTCCAATGAGATCCTCAAGCACATCAACGAGCTGACTATGAAGCTGAGCGT
GGAGGACGTGCTGACCCGCGCCGAGGCCCTGCACCGCCAGCTAACCGCCTGCCCCGAGCTGCCCCACAACGTGCAGGAGATCCTGGGGCT
GGCCCCGCCCGCAGAGCCCCACAGCCCCTCGCCCACCGCCTCCCCGCTGCCTCTGTCGCCCACCCGGGCCCCGCCCACCCCGCCGCCCTC
CACGGACACAGCCCCGCAGCCCGACAGCAGCCTGGAGATCCTGCCCGAGGAGGAGGACGAGGGCGCCGACTCCTAACCCCGCCAGGCAGC
CTCGTTCTGCACAGGCACTTTAGCCCGAGCCAGGCACACCTGCGAGGGGGCAGGTGTGCTCCGCCGCCCTGCTGATAAGCTGGCTTCATT

>58431_58431_13_NEDD4L-TBC1D17_NEDD4L_chr18_55919286_ENST00000400345_TBC1D17_chr19_50381400_ENST00000221543_length(amino acids)=768AA_BP=127
MEAEGRTGRPRRSTAAGSASDPARGAGSMATGLGEPVYGLSEDEGESRILRVKVVSGIDLAKKDIFGASDPYVKLSLYVADENRELALVQ
TKTIKKTLNPKWNEEFYFRVNPSNHRLLFEVFDENRLVVFEKGGVYLHTSAKKYQDRDSLIAGVIRVVEKDNDVLLHWAPVEEAGDSTQI
LFSKKDSSGGDSCASEEEPTFDPDYEPDWAVISTVRPQLCHSEPTRGAEPSCPQGSWAFSVSLGELKSIRRSKPGLSWAYLVLVTQAGGS
LPALHFHRGGTRALLRVLSRYLLLASSPQDSRLYLVFPHDSSALSNSFHHLQLFDQDSSNVVSRFLQDPYSTTFSSFSRVTNFFRGALQP
QPEGAASDLPPPPDDEPEPGFEVISCVELGPRPTVERGPPVTEEEWARHVGPEGRLQQVPELKNRIFSGGLSPSLRREAWKFLLGYLSWE
GTAEEHKAHIRKKTDEYFRMKLQWKSVSPEQERRNSLLHGYRSLIERDVSRTDRTNKFYEGPENPGLGLLNDILLTYCMYHFDLGYVQGM
SDLLSPILYVIQNEVDAFWCFCGFMELVQGNFEESQETMKRQLGRLLLLLRVLDPLLCDFLDSQDSGSLCFCFRWLLIWFKREFPFPDVL
RLWEVLWTGLPGPNLHLLVACAILDMERDTLMLSGFGSNEILKHINELTMKLSVEDVLTRAEALHRQLTACPELPHNVQEILGLAPPAEP

--------------------------------------------------------------
>58431_58431_14_NEDD4L-TBC1D17_NEDD4L_chr18_55919286_ENST00000400345_TBC1D17_chr19_50381755_ENST00000221543_length(transcript)=2527nt_BP=580nt
GCGCGCAGTGAGAGGCGCCGGGGCTGCCGCCCGGTGCTCGGCGCGCTCTCGGGAGCCGCCCGCCCGCTGGTCCCGCAGCCTTCCGGGAGG
AAGCGGTGCCGGCAGCGTCCAGGGCGCGCTCTCGGGCACCCTCACCTGCCGGCGCCCGGCCGCTTACCCGGCAGGGCGTGCGCAGGGTAG
GGTGCGGGACCGGGGGGACCTGGAGGCAGAGGGGAGAACCGGCCGTCCGCGCCGCAGCACAGCCGCTGGGAGCGCCTCAGACCCCGCGCG
GGGCGCCGGCTCCATGGCGACCGGGCTCGGGGAGCCGGTCTATGGACTTTCCGAAGACGAGGGAGAGTCCCGTATTCTCAGAGTAAAAGT
TGTTTCTGGAATTGATCTCGCCAAAAAGGACATCTTTGGAGCCAGTGATCCGTATGTGAAACTTTCATTGTACGTAGCGGATGAGAATAG
AGAACTTGCTTTGGTCCAGACAAAAACAATTAAAAAGACACTGAACCCAAAATGGAATGAAGAATTTTATTTCAGGGTAAACCCATCTAA
TCACAGACTCCTATTTGAAGTATTTGACGAAAATAGACTGGACAATGACGTCCTCCTGCACTGGGCTCCTGTAGAGGAGGCTGGAGATTC
CACCCAAATCCTCTTCTCCAAGAAGGACTCCAGTGGGGGTGACTCATGTGCTTCTGAGGAGGAACCAACCTTTGACCCCGACTATGAACC
TGACTGGGCTGTCATCAGCACTGTGCGGCCACAGCTCTGCCACTCAGAGCCCACGAGAGGTGCAGAGCCCAGCTGCCCCCAGGGCTCCTG
GGCCTTCTCAGTGAGTCTGGGGGAGCTAAAGTCCATCCGCCGCTCCAAGCCAGGCCTCAGCTGGGCCTACCTGGTTCTGGTGACCCAGGC
TGGAGGTTCCCTGCCCGCACTGCACTTCCACCGCGGGGGCACCCGCGCCCTGCTCCGCGTCCTCAGCCGCTACCTGCTGTTGGCCAGCTC
CCCGCAGGACTCCCGCCTCTACCTTGTCTTCCCCCACGACTCCTCTGCTCTCTCCAACTCCTTCCACCACCTGCAGCTCTTTGACCAGGA
CAGCTCCAATGTGGTGTCACGCTTCCTCCAGGATCCCTACTCCACCACCTTCAGCAGCTTCTCCCGAGTGACCAACTTCTTCCGGGGTGC
CCTGCAGCCACAGCCTGAGGGAGCCGCCTCCGACCTTCCCCCGCCACCCGACGATGAGCCCGAGCCTGGATTCGAGGTCATTTCCTGTGT
GGAGCTGGGGCCTCGGCCAACCGTGGAGCGGGGCCCTCCAGTTACAGAGGAGGAGTGGGCACGCCACGTGGGCCCTGAAGGTCGCCTGCA
GCAGGTCCCTGAGCTGAAGAACCGGATCTTCTCGGGGGGTCTGAGCCCCAGCCTGCGGCGCGAGGCCTGGAAGTTCCTCCTAGGGTACCT
CAGCTGGGAAGGCACAGCTGAGGAGCACAAGGCCCACATACGCAAGAAAACGGATGAGTATTTCCGCATGAAGCTGCAGTGGAAATCTGT
GAGCCCTGAGCAGGAGCGGAGAAACTCACTTCTGCATGGATACCGCAGCCTCATCGAAAGGGATGTGAGCCGCACTGACAGGACCAACAA
GTTCTACGAGGGTCCCGAGAACCCGGGGCTGGGCCTGCTGAACGATATCCTCCTCACCTACTGCATGTATCACTTCGACCTCGGCTACGT
CCAGGGCATGAGTGATCTTCTCTCCCCGATCCTCTACGTCATTCAGAACGAGGTGGATGCTTTCTGGTGTTTCTGTGGCTTCATGGAGCT
CGTGCAAGGGAACTTTGAAGAGAGCCAGGAGACCATGAAGCGGCAACTCGGGCGACTGCTGCTGCTCCTGAGGGTGCTGGACCCCCTGCT
CTGCGACTTCCTGGATTCCCAGGACTCCGGCTCTCTCTGCTTCTGTTTCCGGTGGCTGCTCATCTGGTTCAAGAGGGAATTCCCCTTCCC
GGATGTCCTTCGGCTGTGGGAGGTGCTGTGGACAGGGCTCCCTGGCCCCAATCTGCACCTGCTGGTGGCCTGCGCCATCCTGGACATGGA
GAGGGACACCCTCATGCTGTCCGGCTTCGGCTCCAATGAGATCCTCAAGCACATCAACGAGCTGACTATGAAGCTGAGCGTGGAGGACGT
GCTGACCCGCGCCGAGGCCCTGCACCGCCAGCTAACCGCCTGCCCCGAGCTGCCCCACAACGTGCAGGAGATCCTGGGGCTGGCCCCGCC
CGCAGAGCCCCACAGCCCCTCGCCCACCGCCTCCCCGCTGCCTCTGTCGCCCACCCGGGCCCCGCCCACCCCGCCGCCCTCCACGGACAC
AGCCCCGCAGCCCGACAGCAGCCTGGAGATCCTGCCCGAGGAGGAGGACGAGGGCGCCGACTCCTAACCCCGCCAGGCAGCCTCGTTCTG
CACAGGCACTTTAGCCCGAGCCAGGCACACCTGCGAGGGGGCAGGTGTGCTCCGCCGCCCTGCTGATAAGCTGGCTTCATTAAACTGACA

>58431_58431_14_NEDD4L-TBC1D17_NEDD4L_chr18_55919286_ENST00000400345_TBC1D17_chr19_50381755_ENST00000221543_length(amino acids)=735AA_BP=127
MEAEGRTGRPRRSTAAGSASDPARGAGSMATGLGEPVYGLSEDEGESRILRVKVVSGIDLAKKDIFGASDPYVKLSLYVADENRELALVQ
TKTIKKTLNPKWNEEFYFRVNPSNHRLLFEVFDENRLDNDVLLHWAPVEEAGDSTQILFSKKDSSGGDSCASEEEPTFDPDYEPDWAVIS
TVRPQLCHSEPTRGAEPSCPQGSWAFSVSLGELKSIRRSKPGLSWAYLVLVTQAGGSLPALHFHRGGTRALLRVLSRYLLLASSPQDSRL
YLVFPHDSSALSNSFHHLQLFDQDSSNVVSRFLQDPYSTTFSSFSRVTNFFRGALQPQPEGAASDLPPPPDDEPEPGFEVISCVELGPRP
TVERGPPVTEEEWARHVGPEGRLQQVPELKNRIFSGGLSPSLRREAWKFLLGYLSWEGTAEEHKAHIRKKTDEYFRMKLQWKSVSPEQER
RNSLLHGYRSLIERDVSRTDRTNKFYEGPENPGLGLLNDILLTYCMYHFDLGYVQGMSDLLSPILYVIQNEVDAFWCFCGFMELVQGNFE
ESQETMKRQLGRLLLLLRVLDPLLCDFLDSQDSGSLCFCFRWLLIWFKREFPFPDVLRLWEVLWTGLPGPNLHLLVACAILDMERDTLML
SGFGSNEILKHINELTMKLSVEDVLTRAEALHRQLTACPELPHNVQEILGLAPPAEPHSPSPTASPLPLSPTRAPPTPPPSTDTAPQPDS

--------------------------------------------------------------
>58431_58431_15_NEDD4L-TBC1D17_NEDD4L_chr18_55919286_ENST00000400345_TBC1D17_chr19_50381755_ENST00000535102_length(transcript)=2526nt_BP=580nt
GCGCGCAGTGAGAGGCGCCGGGGCTGCCGCCCGGTGCTCGGCGCGCTCTCGGGAGCCGCCCGCCCGCTGGTCCCGCAGCCTTCCGGGAGG
AAGCGGTGCCGGCAGCGTCCAGGGCGCGCTCTCGGGCACCCTCACCTGCCGGCGCCCGGCCGCTTACCCGGCAGGGCGTGCGCAGGGTAG
GGTGCGGGACCGGGGGGACCTGGAGGCAGAGGGGAGAACCGGCCGTCCGCGCCGCAGCACAGCCGCTGGGAGCGCCTCAGACCCCGCGCG
GGGCGCCGGCTCCATGGCGACCGGGCTCGGGGAGCCGGTCTATGGACTTTCCGAAGACGAGGGAGAGTCCCGTATTCTCAGAGTAAAAGT
TGTTTCTGGAATTGATCTCGCCAAAAAGGACATCTTTGGAGCCAGTGATCCGTATGTGAAACTTTCATTGTACGTAGCGGATGAGAATAG
AGAACTTGCTTTGGTCCAGACAAAAACAATTAAAAAGACACTGAACCCAAAATGGAATGAAGAATTTTATTTCAGGGTAAACCCATCTAA
TCACAGACTCCTATTTGAAGTATTTGACGAAAATAGACTGGACAATGACGTCCTCCTGCACTGGGCTCCTGTAGAGGAGGCTGGAGATTC
CACCCAAATCCTCTTCTCCAAGAAGGACTCCAGTGGGGGTGACTCATGTGCTTCTGAGGAGGAACCAACCTTTGACCCCGACTATGAACC
TGACTGGGCTGTCATCAGCACTGTGCGGCCACAGCTCTGCCACTCAGAGCCCACGAGAGGTGCAGAGCCCAGCTGCCCCCAGGGCTCCTG
GGCCTTCTCAGTGAGTCTGGGGGAGCTAAAGTCCATCCGCCGCTCCAAGCCAGGCCTCAGCTGGGCCTACCTGGTTCTGGTGACCCAGGC
TGGAGGTTCCCTGCCCGCACTGCACTTCCACCGCGGGGGCACCCGCGCCCTGCTCCGCGTCCTCAGCCGCTACCTGCTGTTGGCCAGCTC
CCCGCAGGACTCCCGCCTCTACCTTGTCTTCCCCCACGACTCCTCTGCTCTCTCCAACTCCTTCCACCACCTGCAGCTCTTTGACCAGGA
CAGCTCCAATGTGGTGTCACGCTTCCTCCAGGATCCCTACTCCACCACCTTCAGCAGCTTCTCCCGAGTGACCAACTTCTTCCGGGGTGC
CCTGCAGCCACAGCCTGAGGGAGCCGCCTCCGACCTTCCCCCGCCACCCGACGATGAGCCCGAGCCTGGATTCGAGGTCATTTCCTGTGT
GGAGCTGGGGCCTCGGCCAACCGTGGAGCGGGGCCCTCCAGTTACAGAGGAGGAGTGGGCACGCCACGTGGGCCCTGAAGGTCGCCTGCA
GCAGGTCCCTGAGCTGAAGAACCGGATCTTCTCGGGGGGTCTGAGCCCCAGCCTGCGGCGCGAGGCCTGGAAGTTCCTCCTAGGGTACCT
CAGCTGGGAAGGCACAGCTGAGGAGCACAAGGCCCACATACGCAAGAAAACGGATGAGTATTTCCGCATGAAGCTGCAGTGGAAATCTGT
GAGCCCTGAGCAGGAGCGGAGAAACTCACTTCTGCATGGATACCGCAGCCTCATCGAAAGGGATGTGAGCCGCACTGACAGGACCAACAA
GTTCTACGAGGGTCCCGAGAACCCGGGGCTGGGCCTGCTGAACGATATCCTCCTCACCTACTGCATGTATCACTTCGACCTCGGCTACGT
CCAGGGCATGAGTGATCTTCTCTCCCCGATCCTCTACGTCATTCAGAACGAGGTGGATGCTTTCTGGTGTTTCTGTGGCTTCATGGAGCT
CGTGCAAGGGAACTTTGAAGAGAGCCAGGAGACCATGAAGCGGCAACTCGGGCGACTGCTGCTGCTCCTGAGGGTGCTGGACCCCCTGCT
CTGCGACTTCCTGGATTCCCAGGACTCCGGCTCTCTCTGCTTCTGTTTCCGGTGGCTGCTCATCTGGTTCAAGAGGGAATTCCCCTTCCC
GGATGTCCTTCGGCTGTGGGAGGTGCTGTGGACAGGGCTCCCTGGCCCCAATCTGCACCTGCTGGTGGCCTGCGCCATCCTGGACATGGA
GAGGGACACCCTCATGCTGTCCGGCTTCGGCTCCAATGAGATCCTCAAGCACATCAACGAGCTGACTATGAAGCTGAGCGTGGAGGACGT
GCTGACCCGCGCCGAGGCCCTGCACCGCCAGCTAACCGCCTGCCCCGAGCTGCCCCACAACGTGCAGGAGATCCTGGGGCTGGCCCCGCC
CGCAGAGCCCCACAGCCCCTCGCCCACCGCCTCCCCGCTGCCTCTGTCGCCCACCCGGGCCCCGCCCACCCCGCCGCCCTCCACGGACAC
AGCCCCGCAGCCCGACAGCAGCCTGGAGATCCTGCCCGAGGAGGAGGACGAGGGCGCCGACTCCTAACCCCGCCAGGCAGCCTCGTTCTG
CACAGGCACTTTAGCCCGAGCCAGGCACACCTGCGAGGGGGCAGGTGTGCTCCGCCGCCCTGCTGATAAGCTGGCTTCATTAAACTGACA

>58431_58431_15_NEDD4L-TBC1D17_NEDD4L_chr18_55919286_ENST00000400345_TBC1D17_chr19_50381755_ENST00000535102_length(amino acids)=735AA_BP=127
MEAEGRTGRPRRSTAAGSASDPARGAGSMATGLGEPVYGLSEDEGESRILRVKVVSGIDLAKKDIFGASDPYVKLSLYVADENRELALVQ
TKTIKKTLNPKWNEEFYFRVNPSNHRLLFEVFDENRLDNDVLLHWAPVEEAGDSTQILFSKKDSSGGDSCASEEEPTFDPDYEPDWAVIS
TVRPQLCHSEPTRGAEPSCPQGSWAFSVSLGELKSIRRSKPGLSWAYLVLVTQAGGSLPALHFHRGGTRALLRVLSRYLLLASSPQDSRL
YLVFPHDSSALSNSFHHLQLFDQDSSNVVSRFLQDPYSTTFSSFSRVTNFFRGALQPQPEGAASDLPPPPDDEPEPGFEVISCVELGPRP
TVERGPPVTEEEWARHVGPEGRLQQVPELKNRIFSGGLSPSLRREAWKFLLGYLSWEGTAEEHKAHIRKKTDEYFRMKLQWKSVSPEQER
RNSLLHGYRSLIERDVSRTDRTNKFYEGPENPGLGLLNDILLTYCMYHFDLGYVQGMSDLLSPILYVIQNEVDAFWCFCGFMELVQGNFE
ESQETMKRQLGRLLLLLRVLDPLLCDFLDSQDSGSLCFCFRWLLIWFKREFPFPDVLRLWEVLWTGLPGPNLHLLVACAILDMERDTLML
SGFGSNEILKHINELTMKLSVEDVLTRAEALHRQLTACPELPHNVQEILGLAPPAEPHSPSPTASPLPLSPTRAPPTPPPSTDTAPQPDS

--------------------------------------------------------------
>58431_58431_16_NEDD4L-TBC1D17_NEDD4L_chr18_55919286_ENST00000586263_TBC1D17_chr19_50381400_ENST00000221543_length(transcript)=2518nt_BP=472nt
TTTCCAGAGAGGAACAACCGTGTAGACTGCTTTCCTGGGAGTCAAGTTAAAACTTCTCTCCTGTGACCTTGTCACCCGGCAGTGGAAAGT
TACCCTTGGCTGCAGCCACGACTTCCGCATACTCTTCAGAACTTGCTCTGCCCTTGAGTTTTCCAGCTTTCCTTTAATGCACTAAACCTT
TAATATTGTATTCTCCTAAATGAGACGTCTCGCATTTGAGCAGGGAGAGTCCCGTATTCTCAGAGTAAAAGTTGTTTCTGGAATTGATCT
CGCCAAAAAGGACATCTTTGGAGCCAGTGATCCGTATGTGAAACTTTCATTGTACGTAGCGGATGAGAATAGAGAACTTGCTTTGGTCCA
GACAAAAACAATTAAAAAGACACTGAACCCAAAATGGAATGAAGAATTTTATTTCAGGGTAAACCCATCTAATCACAGACTCCTATTTGA
AGTATTTGACGAAAATAGACTGGTGGTGTTTGAGAAGGGCGGAGTGTACCTGCACACCAGCGCTAAGAAGTATCAGGACCGAGACTCTCT
CATCGCTGGTGTCATCCGTGTCGTGGAAAAGGACAATGACGTCCTCCTGCACTGGGCTCCTGTAGAGGAGGCTGGAGATTCCACCCAAAT
CCTCTTCTCCAAGAAGGACTCCAGTGGGGGTGACTCATGTGCTTCTGAGGAGGAACCAACCTTTGACCCCGACTATGAACCTGACTGGGC
TGTCATCAGCACTGTGCGGCCACAGCTCTGCCACTCAGAGCCCACGAGAGGTGCAGAGCCCAGCTGCCCCCAGGGCTCCTGGGCCTTCTC
AGTGAGTCTGGGGGAGCTAAAGTCCATCCGCCGCTCCAAGCCAGGCCTCAGCTGGGCCTACCTGGTTCTGGTGACCCAGGCTGGAGGTTC
CCTGCCCGCACTGCACTTCCACCGCGGGGGCACCCGCGCCCTGCTCCGCGTCCTCAGCCGCTACCTGCTGTTGGCCAGCTCCCCGCAGGA
CTCCCGCCTCTACCTTGTCTTCCCCCACGACTCCTCTGCTCTCTCCAACTCCTTCCACCACCTGCAGCTCTTTGACCAGGACAGCTCCAA
TGTGGTGTCACGCTTCCTCCAGGATCCCTACTCCACCACCTTCAGCAGCTTCTCCCGAGTGACCAACTTCTTCCGGGGTGCCCTGCAGCC
ACAGCCTGAGGGAGCCGCCTCCGACCTTCCCCCGCCACCCGACGATGAGCCCGAGCCTGGATTCGAGGTCATTTCCTGTGTGGAGCTGGG
GCCTCGGCCAACCGTGGAGCGGGGCCCTCCAGTTACAGAGGAGGAGTGGGCACGCCACGTGGGCCCTGAAGGTCGCCTGCAGCAGGTCCC
TGAGCTGAAGAACCGGATCTTCTCGGGGGGTCTGAGCCCCAGCCTGCGGCGCGAGGCCTGGAAGTTCCTCCTAGGGTACCTCAGCTGGGA
AGGCACAGCTGAGGAGCACAAGGCCCACATACGCAAGAAAACGGATGAGTATTTCCGCATGAAGCTGCAGTGGAAATCTGTGAGCCCTGA
GCAGGAGCGGAGAAACTCACTTCTGCATGGATACCGCAGCCTCATCGAAAGGGATGTGAGCCGCACTGACAGGACCAACAAGTTCTACGA
GGGTCCCGAGAACCCGGGGCTGGGCCTGCTGAACGATATCCTCCTCACCTACTGCATGTATCACTTCGACCTCGGCTACGTCCAGGGCAT
GAGTGATCTTCTCTCCCCGATCCTCTACGTCATTCAGAACGAGGTGGATGCTTTCTGGTGTTTCTGTGGCTTCATGGAGCTCGTGCAAGG
GAACTTTGAAGAGAGCCAGGAGACCATGAAGCGGCAACTCGGGCGACTGCTGCTGCTCCTGAGGGTGCTGGACCCCCTGCTCTGCGACTT
CCTGGATTCCCAGGACTCCGGCTCTCTCTGCTTCTGTTTCCGGTGGCTGCTCATCTGGTTCAAGAGGGAATTCCCCTTCCCGGATGTCCT
TCGGCTGTGGGAGGTGCTGTGGACAGGGCTCCCTGGCCCCAATCTGCACCTGCTGGTGGCCTGCGCCATCCTGGACATGGAGAGGGACAC
CCTCATGCTGTCCGGCTTCGGCTCCAATGAGATCCTCAAGCACATCAACGAGCTGACTATGAAGCTGAGCGTGGAGGACGTGCTGACCCG
CGCCGAGGCCCTGCACCGCCAGCTAACCGCCTGCCCCGAGCTGCCCCACAACGTGCAGGAGATCCTGGGGCTGGCCCCGCCCGCAGAGCC
CCACAGCCCCTCGCCCACCGCCTCCCCGCTGCCTCTGTCGCCCACCCGGGCCCCGCCCACCCCGCCGCCCTCCACGGACACAGCCCCGCA
GCCCGACAGCAGCCTGGAGATCCTGCCCGAGGAGGAGGACGAGGGCGCCGACTCCTAACCCCGCCAGGCAGCCTCGTTCTGCACAGGCAC

>58431_58431_16_NEDD4L-TBC1D17_NEDD4L_chr18_55919286_ENST00000586263_TBC1D17_chr19_50381400_ENST00000221543_length(amino acids)=732AA_BP=91
MRRLAFEQGESRILRVKVVSGIDLAKKDIFGASDPYVKLSLYVADENRELALVQTKTIKKTLNPKWNEEFYFRVNPSNHRLLFEVFDENR
LVVFEKGGVYLHTSAKKYQDRDSLIAGVIRVVEKDNDVLLHWAPVEEAGDSTQILFSKKDSSGGDSCASEEEPTFDPDYEPDWAVISTVR
PQLCHSEPTRGAEPSCPQGSWAFSVSLGELKSIRRSKPGLSWAYLVLVTQAGGSLPALHFHRGGTRALLRVLSRYLLLASSPQDSRLYLV
FPHDSSALSNSFHHLQLFDQDSSNVVSRFLQDPYSTTFSSFSRVTNFFRGALQPQPEGAASDLPPPPDDEPEPGFEVISCVELGPRPTVE
RGPPVTEEEWARHVGPEGRLQQVPELKNRIFSGGLSPSLRREAWKFLLGYLSWEGTAEEHKAHIRKKTDEYFRMKLQWKSVSPEQERRNS
LLHGYRSLIERDVSRTDRTNKFYEGPENPGLGLLNDILLTYCMYHFDLGYVQGMSDLLSPILYVIQNEVDAFWCFCGFMELVQGNFEESQ
ETMKRQLGRLLLLLRVLDPLLCDFLDSQDSGSLCFCFRWLLIWFKREFPFPDVLRLWEVLWTGLPGPNLHLLVACAILDMERDTLMLSGF
GSNEILKHINELTMKLSVEDVLTRAEALHRQLTACPELPHNVQEILGLAPPAEPHSPSPTASPLPLSPTRAPPTPPPSTDTAPQPDSSLE

--------------------------------------------------------------
>58431_58431_17_NEDD4L-TBC1D17_NEDD4L_chr18_55919286_ENST00000586263_TBC1D17_chr19_50381755_ENST00000221543_length(transcript)=2419nt_BP=472nt
TTTCCAGAGAGGAACAACCGTGTAGACTGCTTTCCTGGGAGTCAAGTTAAAACTTCTCTCCTGTGACCTTGTCACCCGGCAGTGGAAAGT
TACCCTTGGCTGCAGCCACGACTTCCGCATACTCTTCAGAACTTGCTCTGCCCTTGAGTTTTCCAGCTTTCCTTTAATGCACTAAACCTT
TAATATTGTATTCTCCTAAATGAGACGTCTCGCATTTGAGCAGGGAGAGTCCCGTATTCTCAGAGTAAAAGTTGTTTCTGGAATTGATCT
CGCCAAAAAGGACATCTTTGGAGCCAGTGATCCGTATGTGAAACTTTCATTGTACGTAGCGGATGAGAATAGAGAACTTGCTTTGGTCCA
GACAAAAACAATTAAAAAGACACTGAACCCAAAATGGAATGAAGAATTTTATTTCAGGGTAAACCCATCTAATCACAGACTCCTATTTGA
AGTATTTGACGAAAATAGACTGGACAATGACGTCCTCCTGCACTGGGCTCCTGTAGAGGAGGCTGGAGATTCCACCCAAATCCTCTTCTC
CAAGAAGGACTCCAGTGGGGGTGACTCATGTGCTTCTGAGGAGGAACCAACCTTTGACCCCGACTATGAACCTGACTGGGCTGTCATCAG
CACTGTGCGGCCACAGCTCTGCCACTCAGAGCCCACGAGAGGTGCAGAGCCCAGCTGCCCCCAGGGCTCCTGGGCCTTCTCAGTGAGTCT
GGGGGAGCTAAAGTCCATCCGCCGCTCCAAGCCAGGCCTCAGCTGGGCCTACCTGGTTCTGGTGACCCAGGCTGGAGGTTCCCTGCCCGC
ACTGCACTTCCACCGCGGGGGCACCCGCGCCCTGCTCCGCGTCCTCAGCCGCTACCTGCTGTTGGCCAGCTCCCCGCAGGACTCCCGCCT
CTACCTTGTCTTCCCCCACGACTCCTCTGCTCTCTCCAACTCCTTCCACCACCTGCAGCTCTTTGACCAGGACAGCTCCAATGTGGTGTC
ACGCTTCCTCCAGGATCCCTACTCCACCACCTTCAGCAGCTTCTCCCGAGTGACCAACTTCTTCCGGGGTGCCCTGCAGCCACAGCCTGA
GGGAGCCGCCTCCGACCTTCCCCCGCCACCCGACGATGAGCCCGAGCCTGGATTCGAGGTCATTTCCTGTGTGGAGCTGGGGCCTCGGCC
AACCGTGGAGCGGGGCCCTCCAGTTACAGAGGAGGAGTGGGCACGCCACGTGGGCCCTGAAGGTCGCCTGCAGCAGGTCCCTGAGCTGAA
GAACCGGATCTTCTCGGGGGGTCTGAGCCCCAGCCTGCGGCGCGAGGCCTGGAAGTTCCTCCTAGGGTACCTCAGCTGGGAAGGCACAGC
TGAGGAGCACAAGGCCCACATACGCAAGAAAACGGATGAGTATTTCCGCATGAAGCTGCAGTGGAAATCTGTGAGCCCTGAGCAGGAGCG
GAGAAACTCACTTCTGCATGGATACCGCAGCCTCATCGAAAGGGATGTGAGCCGCACTGACAGGACCAACAAGTTCTACGAGGGTCCCGA
GAACCCGGGGCTGGGCCTGCTGAACGATATCCTCCTCACCTACTGCATGTATCACTTCGACCTCGGCTACGTCCAGGGCATGAGTGATCT
TCTCTCCCCGATCCTCTACGTCATTCAGAACGAGGTGGATGCTTTCTGGTGTTTCTGTGGCTTCATGGAGCTCGTGCAAGGGAACTTTGA
AGAGAGCCAGGAGACCATGAAGCGGCAACTCGGGCGACTGCTGCTGCTCCTGAGGGTGCTGGACCCCCTGCTCTGCGACTTCCTGGATTC
CCAGGACTCCGGCTCTCTCTGCTTCTGTTTCCGGTGGCTGCTCATCTGGTTCAAGAGGGAATTCCCCTTCCCGGATGTCCTTCGGCTGTG
GGAGGTGCTGTGGACAGGGCTCCCTGGCCCCAATCTGCACCTGCTGGTGGCCTGCGCCATCCTGGACATGGAGAGGGACACCCTCATGCT
GTCCGGCTTCGGCTCCAATGAGATCCTCAAGCACATCAACGAGCTGACTATGAAGCTGAGCGTGGAGGACGTGCTGACCCGCGCCGAGGC
CCTGCACCGCCAGCTAACCGCCTGCCCCGAGCTGCCCCACAACGTGCAGGAGATCCTGGGGCTGGCCCCGCCCGCAGAGCCCCACAGCCC
CTCGCCCACCGCCTCCCCGCTGCCTCTGTCGCCCACCCGGGCCCCGCCCACCCCGCCGCCCTCCACGGACACAGCCCCGCAGCCCGACAG
CAGCCTGGAGATCCTGCCCGAGGAGGAGGACGAGGGCGCCGACTCCTAACCCCGCCAGGCAGCCTCGTTCTGCACAGGCACTTTAGCCCG

>58431_58431_17_NEDD4L-TBC1D17_NEDD4L_chr18_55919286_ENST00000586263_TBC1D17_chr19_50381755_ENST00000221543_length(amino acids)=699AA_BP=91
MRRLAFEQGESRILRVKVVSGIDLAKKDIFGASDPYVKLSLYVADENRELALVQTKTIKKTLNPKWNEEFYFRVNPSNHRLLFEVFDENR
LDNDVLLHWAPVEEAGDSTQILFSKKDSSGGDSCASEEEPTFDPDYEPDWAVISTVRPQLCHSEPTRGAEPSCPQGSWAFSVSLGELKSI
RRSKPGLSWAYLVLVTQAGGSLPALHFHRGGTRALLRVLSRYLLLASSPQDSRLYLVFPHDSSALSNSFHHLQLFDQDSSNVVSRFLQDP
YSTTFSSFSRVTNFFRGALQPQPEGAASDLPPPPDDEPEPGFEVISCVELGPRPTVERGPPVTEEEWARHVGPEGRLQQVPELKNRIFSG
GLSPSLRREAWKFLLGYLSWEGTAEEHKAHIRKKTDEYFRMKLQWKSVSPEQERRNSLLHGYRSLIERDVSRTDRTNKFYEGPENPGLGL
LNDILLTYCMYHFDLGYVQGMSDLLSPILYVIQNEVDAFWCFCGFMELVQGNFEESQETMKRQLGRLLLLLRVLDPLLCDFLDSQDSGSL
CFCFRWLLIWFKREFPFPDVLRLWEVLWTGLPGPNLHLLVACAILDMERDTLMLSGFGSNEILKHINELTMKLSVEDVLTRAEALHRQLT

--------------------------------------------------------------
>58431_58431_18_NEDD4L-TBC1D17_NEDD4L_chr18_55919286_ENST00000586263_TBC1D17_chr19_50381755_ENST00000535102_length(transcript)=2418nt_BP=472nt
TTTCCAGAGAGGAACAACCGTGTAGACTGCTTTCCTGGGAGTCAAGTTAAAACTTCTCTCCTGTGACCTTGTCACCCGGCAGTGGAAAGT
TACCCTTGGCTGCAGCCACGACTTCCGCATACTCTTCAGAACTTGCTCTGCCCTTGAGTTTTCCAGCTTTCCTTTAATGCACTAAACCTT
TAATATTGTATTCTCCTAAATGAGACGTCTCGCATTTGAGCAGGGAGAGTCCCGTATTCTCAGAGTAAAAGTTGTTTCTGGAATTGATCT
CGCCAAAAAGGACATCTTTGGAGCCAGTGATCCGTATGTGAAACTTTCATTGTACGTAGCGGATGAGAATAGAGAACTTGCTTTGGTCCA
GACAAAAACAATTAAAAAGACACTGAACCCAAAATGGAATGAAGAATTTTATTTCAGGGTAAACCCATCTAATCACAGACTCCTATTTGA
AGTATTTGACGAAAATAGACTGGACAATGACGTCCTCCTGCACTGGGCTCCTGTAGAGGAGGCTGGAGATTCCACCCAAATCCTCTTCTC
CAAGAAGGACTCCAGTGGGGGTGACTCATGTGCTTCTGAGGAGGAACCAACCTTTGACCCCGACTATGAACCTGACTGGGCTGTCATCAG
CACTGTGCGGCCACAGCTCTGCCACTCAGAGCCCACGAGAGGTGCAGAGCCCAGCTGCCCCCAGGGCTCCTGGGCCTTCTCAGTGAGTCT
GGGGGAGCTAAAGTCCATCCGCCGCTCCAAGCCAGGCCTCAGCTGGGCCTACCTGGTTCTGGTGACCCAGGCTGGAGGTTCCCTGCCCGC
ACTGCACTTCCACCGCGGGGGCACCCGCGCCCTGCTCCGCGTCCTCAGCCGCTACCTGCTGTTGGCCAGCTCCCCGCAGGACTCCCGCCT
CTACCTTGTCTTCCCCCACGACTCCTCTGCTCTCTCCAACTCCTTCCACCACCTGCAGCTCTTTGACCAGGACAGCTCCAATGTGGTGTC
ACGCTTCCTCCAGGATCCCTACTCCACCACCTTCAGCAGCTTCTCCCGAGTGACCAACTTCTTCCGGGGTGCCCTGCAGCCACAGCCTGA
GGGAGCCGCCTCCGACCTTCCCCCGCCACCCGACGATGAGCCCGAGCCTGGATTCGAGGTCATTTCCTGTGTGGAGCTGGGGCCTCGGCC
AACCGTGGAGCGGGGCCCTCCAGTTACAGAGGAGGAGTGGGCACGCCACGTGGGCCCTGAAGGTCGCCTGCAGCAGGTCCCTGAGCTGAA
GAACCGGATCTTCTCGGGGGGTCTGAGCCCCAGCCTGCGGCGCGAGGCCTGGAAGTTCCTCCTAGGGTACCTCAGCTGGGAAGGCACAGC
TGAGGAGCACAAGGCCCACATACGCAAGAAAACGGATGAGTATTTCCGCATGAAGCTGCAGTGGAAATCTGTGAGCCCTGAGCAGGAGCG
GAGAAACTCACTTCTGCATGGATACCGCAGCCTCATCGAAAGGGATGTGAGCCGCACTGACAGGACCAACAAGTTCTACGAGGGTCCCGA
GAACCCGGGGCTGGGCCTGCTGAACGATATCCTCCTCACCTACTGCATGTATCACTTCGACCTCGGCTACGTCCAGGGCATGAGTGATCT
TCTCTCCCCGATCCTCTACGTCATTCAGAACGAGGTGGATGCTTTCTGGTGTTTCTGTGGCTTCATGGAGCTCGTGCAAGGGAACTTTGA
AGAGAGCCAGGAGACCATGAAGCGGCAACTCGGGCGACTGCTGCTGCTCCTGAGGGTGCTGGACCCCCTGCTCTGCGACTTCCTGGATTC
CCAGGACTCCGGCTCTCTCTGCTTCTGTTTCCGGTGGCTGCTCATCTGGTTCAAGAGGGAATTCCCCTTCCCGGATGTCCTTCGGCTGTG
GGAGGTGCTGTGGACAGGGCTCCCTGGCCCCAATCTGCACCTGCTGGTGGCCTGCGCCATCCTGGACATGGAGAGGGACACCCTCATGCT
GTCCGGCTTCGGCTCCAATGAGATCCTCAAGCACATCAACGAGCTGACTATGAAGCTGAGCGTGGAGGACGTGCTGACCCGCGCCGAGGC
CCTGCACCGCCAGCTAACCGCCTGCCCCGAGCTGCCCCACAACGTGCAGGAGATCCTGGGGCTGGCCCCGCCCGCAGAGCCCCACAGCCC
CTCGCCCACCGCCTCCCCGCTGCCTCTGTCGCCCACCCGGGCCCCGCCCACCCCGCCGCCCTCCACGGACACAGCCCCGCAGCCCGACAG
CAGCCTGGAGATCCTGCCCGAGGAGGAGGACGAGGGCGCCGACTCCTAACCCCGCCAGGCAGCCTCGTTCTGCACAGGCACTTTAGCCCG

>58431_58431_18_NEDD4L-TBC1D17_NEDD4L_chr18_55919286_ENST00000586263_TBC1D17_chr19_50381755_ENST00000535102_length(amino acids)=699AA_BP=91
MRRLAFEQGESRILRVKVVSGIDLAKKDIFGASDPYVKLSLYVADENRELALVQTKTIKKTLNPKWNEEFYFRVNPSNHRLLFEVFDENR
LDNDVLLHWAPVEEAGDSTQILFSKKDSSGGDSCASEEEPTFDPDYEPDWAVISTVRPQLCHSEPTRGAEPSCPQGSWAFSVSLGELKSI
RRSKPGLSWAYLVLVTQAGGSLPALHFHRGGTRALLRVLSRYLLLASSPQDSRLYLVFPHDSSALSNSFHHLQLFDQDSSNVVSRFLQDP
YSTTFSSFSRVTNFFRGALQPQPEGAASDLPPPPDDEPEPGFEVISCVELGPRPTVERGPPVTEEEWARHVGPEGRLQQVPELKNRIFSG
GLSPSLRREAWKFLLGYLSWEGTAEEHKAHIRKKTDEYFRMKLQWKSVSPEQERRNSLLHGYRSLIERDVSRTDRTNKFYEGPENPGLGL
LNDILLTYCMYHFDLGYVQGMSDLLSPILYVIQNEVDAFWCFCGFMELVQGNFEESQETMKRQLGRLLLLLRVLDPLLCDFLDSQDSGSL
CFCFRWLLIWFKREFPFPDVLRLWEVLWTGLPGPNLHLLVACAILDMERDTLMLSGFGSNEILKHINELTMKLSVEDVLTRAEALHRQLT

--------------------------------------------------------------

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Fusion Gene PPI Analysis for NEDD4L-TBC1D17


check button Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in

ChiPPI page.


check button Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160)
HgeneHgene's interactorsTgeneTgene's interactors


check button - Retained PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenStill interaction with


check button - Lost PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


check button - Retained PPIs, but lost function due to frame-shift fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


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Related Drugs for NEDD4L-TBC1D17


check button Drugs targeting genes involved in this fusion gene.
(DrugBank Version 5.1.8 2021-05-08)
PartnerGeneUniProtAccDrugBank IDDrug nameDrug activityDrug typeDrug status

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Related Diseases for NEDD4L-TBC1D17


check button Diseases associated with fusion partners.
(DisGeNet 4.0)
PartnerGeneDisease IDDisease name# pubmedsSource