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Center for Computational Systems Medicine
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Fusion Gene Summary

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Fusion Gene ORF analysis

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Fusion Genomic Features

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Fusion Protein Features

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Fusion Gene Sequence

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Fusion Gene PPI analysis

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Related Drugs

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Related Diseases

Fusion gene:NFATC3-SPATA33 (FusionGDB2 ID:58810)

Fusion Gene Summary for NFATC3-SPATA33

check button Fusion gene summary
Fusion gene informationFusion gene name: NFATC3-SPATA33
Fusion gene ID: 58810
HgeneTgene
Gene symbol

NFATC3

SPATA33

Gene ID

4775

124045

Gene namenuclear factor of activated T cells 3spermatogenesis associated 33
SynonymsNF-AT4c|NFAT4|NFATXC16orf55
Cytomap

16q22.1

16q24.3

Type of geneprotein-codingprotein-coding
Descriptionnuclear factor of activated T-cells, cytoplasmic 3NF-ATc3T cell transcription factor NFAT4nuclear factor of activated T-cells c3 isoform IE-Xanuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 3spermatogenesis-associated protein 33
Modification date2020031320200313
UniProtAcc

Q12968

Q96N06

Ensembl transtripts involved in fusion geneENST00000535127, ENST00000329524, 
ENST00000346183, ENST00000349223, 
ENST00000575270, 		ENST00000301031, 
ENST00000579310, ENST00000566857, 
ENST00000568929, 
Fusion gene scores* DoF score9 X 4 X 9=3243 X 1 X 3=9
# samples 113
** MAII scorelog2(11/324*10)=-1.55849028935997
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0		log2(3/9*10)=1.73696559416621
effective Gene in Pan-Cancer Fusion Genes (eGinPCFGs).
DoF>8 and MAII>0
Context

PubMed: NFATC3 [Title/Abstract] AND SPATA33 [Title/Abstract] AND fusion [Title/Abstract]

Most frequent breakpointNFATC3(68225678)-SPATA33(89735694), # samples:2
Anticipated loss of major functional domain due to fusion event.NFATC3-SPATA33 seems lost the major protein functional domain in Hgene partner, which is a transcription factor due to the frame-shifted ORF.
* DoF score (Degree of Frequency) = # partners X # break points X # cancer types
** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)

check button Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez
PartnerGeneGO IDGO termPubMed ID
HgeneNFATC3

GO:0045944

positive regulation of transcription by RNA polymerase II

18815128

HgeneNFATC3

GO:1905064

negative regulation of vascular smooth muscle cell differentiation

23853098


check buttonFusion gene breakpoints across NFATC3 (5'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check buttonFusion gene breakpoints across SPATA33 (3'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check button Fusion gene information from two resources (ChiTars 5.0 and ChimerDB 4.0)
* All genome coordinats were lifted-over on hg19.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
SourceDiseaseSampleHgeneHchrHbpHstrandTgeneTchrTbpTstrand
ChimerDB4PRADTCGA-M7-A724-01ANFATC3chr16

68225678

+SPATA33chr16

89735694

+
ChimerDB4PRADTCGA-M7-A724NFATC3chr16

68225678

+SPATA33chr16

89735694

+


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Fusion Gene ORF analysis for NFATC3-SPATA33

check button Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
ORFHenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrand
3UTR-3CDSENST00000535127ENST00000301031NFATC3chr16

68225678

+SPATA33chr16

89735694

+
3UTR-3CDSENST00000535127ENST00000579310NFATC3chr16

68225678

+SPATA33chr16

89735694

+
3UTR-intronENST00000535127ENST00000566857NFATC3chr16

68225678

+SPATA33chr16

89735694

+
3UTR-intronENST00000535127ENST00000568929NFATC3chr16

68225678

+SPATA33chr16

89735694

+
5CDS-intronENST00000329524ENST00000566857NFATC3chr16

68225678

+SPATA33chr16

89735694

+
5CDS-intronENST00000329524ENST00000568929NFATC3chr16

68225678

+SPATA33chr16

89735694

+
5CDS-intronENST00000346183ENST00000566857NFATC3chr16

68225678

+SPATA33chr16

89735694

+
5CDS-intronENST00000346183ENST00000568929NFATC3chr16

68225678

+SPATA33chr16

89735694

+
5CDS-intronENST00000349223ENST00000566857NFATC3chr16

68225678

+SPATA33chr16

89735694

+
5CDS-intronENST00000349223ENST00000568929NFATC3chr16

68225678

+SPATA33chr16

89735694

+
5CDS-intronENST00000575270ENST00000566857NFATC3chr16

68225678

+SPATA33chr16

89735694

+
5CDS-intronENST00000575270ENST00000568929NFATC3chr16

68225678

+SPATA33chr16

89735694

+
Frame-shiftENST00000329524ENST00000301031NFATC3chr16

68225678

+SPATA33chr16

89735694

+
Frame-shiftENST00000346183ENST00000301031NFATC3chr16

68225678

+SPATA33chr16

89735694

+
Frame-shiftENST00000349223ENST00000301031NFATC3chr16

68225678

+SPATA33chr16

89735694

+
Frame-shiftENST00000575270ENST00000301031NFATC3chr16

68225678

+SPATA33chr16

89735694

+
In-frameENST00000329524ENST00000579310NFATC3chr16

68225678

+SPATA33chr16

89735694

+
In-frameENST00000346183ENST00000579310NFATC3chr16

68225678

+SPATA33chr16

89735694

+
In-frameENST00000349223ENST00000579310NFATC3chr16

68225678

+SPATA33chr16

89735694

+
In-frameENST00000575270ENST00000579310NFATC3chr16

68225678

+SPATA33chr16

89735694

+

check buttonORFfinder result based on the fusion transcript sequence of in-frame fusion genes.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandSeq length
(transcript)		BP loci
(transcript)		Predicted start
(transcript)		Predicted stop
(transcript)		Seq length
(amino acids)
ENST00000575270NFATC3chr1668225678+ENST00000579310SPATA33chr1689735694+4456344433836551105
ENST00000349223NFATC3chr1668225678+ENST00000579310SPATA33chr1689735694+4342333022435411105
ENST00000329524NFATC3chr1668225678+ENST00000579310SPATA33chr1689735694+414231302433411105
ENST00000346183NFATC3chr1668225678+ENST00000579310SPATA33chr1689735694+414231302433411105

check buttonDeepORF prediction of the coding potential based on the fusion transcript sequence of in-frame fusion genes. DeepORF is a coding potential classifier based on convolutional neural network by comparing the real Ribo-seq data. If the no-coding score < 0.5 and coding score > 0.5, then the in-frame fusion transcript is predicted as being likely translated.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandNo-coding scoreCoding score
ENST00000575270ENST00000579310NFATC3chr1668225678+SPATA33chr1689735694+0.0024437330.9975562
ENST00000349223ENST00000579310NFATC3chr1668225678+SPATA33chr1689735694+0.0022536520.9977463
ENST00000329524ENST00000579310NFATC3chr1668225678+SPATA33chr1689735694+0.0017152320.99828476
ENST00000346183ENST00000579310NFATC3chr1668225678+SPATA33chr1689735694+0.0017152320.99828476

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Fusion Genomic Features for NFATC3-SPATA33


check buttonFusionAI prediction of the potential fusion gene breakpoint based on the pre-mature RNA sequence context (+/- 5kb of individual partner genes, total 20kb length sequence). FusionAI is a fusion gene breakpoint classifier based on convolutional neural network by comparing the fusion positive and negative sequence context of ~ 20K fusion gene data. From here, we can have the relative potentency of the 20K genomic sequence how individual sequnce will be likely used as the gene fusion breakpoints.
HgeneHchrHbpHstrandTgeneTchrTbpTstrand1-pp (fusion gene breakpoint)
NFATC3chr1668225678+SPATA33chr1689735693+5.06E-060.999995
NFATC3chr1668225678+SPATA33chr1689735693+5.06E-060.999995
NFATC3chr1668225678+SPATA33chr1689735693+5.06E-060.999995
NFATC3chr1668225678+SPATA33chr1689735693+5.06E-060.999995

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions. We integrated a total of 44 different types of human genomic feature loci information across five big categories including virus integration sites, repeats, structural variants, chromatin states, and gene expression regulation. More details are in help page.
genomic feature

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions that are ovelapped with the top 1% feature importance score regions. More details are in help page.
genomic feature of top 1%

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Fusion Protein Features for NFATC3-SPATA33


check button Four levels of functional features of fusion genes
Go to FGviewer search page for the most frequent breakpoint (https://ccsmweb.uth.edu/FGviewer/chr16:68225678/chr16:89735694)
- FGviewer provides the online visualization of the retention search of the protein functional features across DNA, RNA, protein, and pathological levels.
- How to search
1. Put your fusion gene symbol.
2. Press the tab key until there will be shown the breakpoint information filled.
4. Go down and press 'Search' tab twice.
4. Go down to have the hyperlink of the search result.
5. Click the hyperlink.
6. See the FGviewer result for your fusion gene.
FGviewer

check buttonMain function of each fusion partner protein. (from UniProt)
HgeneTgene
NFATC3

Q12968

SPATA33

Q96N06

FUNCTION: Acts as a regulator of transcriptional activation. Plays a role in the inducible expression of cytokine genes in T-cells, especially in the induction of the IL-2 (PubMed:18815128). Along with NFATC4, involved in embryonic heart development (By similarity). {ECO:0000250|UniProtKB:P97305, ECO:0000269|PubMed:18815128}.

check buttonRetention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at

download page


* Minus value of BPloci means that the break pointn is located before the CDS.
- In-frame and retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneNFATC3chr16:68225678chr16:89735694ENST00000329524+91124_2910351996.6666666666667Compositional biasNote=Poly-Pro
HgeneNFATC3chr16:68225678chr16:89735694ENST00000346183+91024_2910351076.0Compositional biasNote=Poly-Pro
HgeneNFATC3chr16:68225678chr16:89735694ENST00000349223+91124_2910351066.0Compositional biasNote=Poly-Pro
HgeneNFATC3chr16:68225678chr16:89735694ENST00000329524+911444_45110351996.6666666666667DNA binding.
HgeneNFATC3chr16:68225678chr16:89735694ENST00000346183+910444_45110351076.0DNA binding.
HgeneNFATC3chr16:68225678chr16:89735694ENST00000349223+911444_45110351066.0DNA binding.
HgeneNFATC3chr16:68225678chr16:89735694ENST00000329524+911415_59610351996.6666666666667DomainRHD
HgeneNFATC3chr16:68225678chr16:89735694ENST00000346183+910415_59610351076.0DomainRHD
HgeneNFATC3chr16:68225678chr16:89735694ENST00000349223+911415_59610351066.0DomainRHD
HgeneNFATC3chr16:68225678chr16:89735694ENST00000329524+911273_27510351996.6666666666667MotifNote=Nuclear localization signal
HgeneNFATC3chr16:68225678chr16:89735694ENST00000329524+911686_68810351996.6666666666667MotifNote=Nuclear localization signal
HgeneNFATC3chr16:68225678chr16:89735694ENST00000346183+910273_27510351076.0MotifNote=Nuclear localization signal
HgeneNFATC3chr16:68225678chr16:89735694ENST00000346183+910686_68810351076.0MotifNote=Nuclear localization signal
HgeneNFATC3chr16:68225678chr16:89735694ENST00000349223+911273_27510351066.0MotifNote=Nuclear localization signal
HgeneNFATC3chr16:68225678chr16:89735694ENST00000349223+911686_68810351066.0MotifNote=Nuclear localization signal
HgeneNFATC3chr16:68225678chr16:89735694ENST00000329524+911109_11410351996.6666666666667RegionNote=Calcineurin-binding
HgeneNFATC3chr16:68225678chr16:89735694ENST00000329524+911207_30810351996.6666666666667RegionNote=3 X SP repeats
HgeneNFATC3chr16:68225678chr16:89735694ENST00000346183+910109_11410351076.0RegionNote=Calcineurin-binding
HgeneNFATC3chr16:68225678chr16:89735694ENST00000346183+910207_30810351076.0RegionNote=3 X SP repeats
HgeneNFATC3chr16:68225678chr16:89735694ENST00000349223+911109_11410351066.0RegionNote=Calcineurin-binding
HgeneNFATC3chr16:68225678chr16:89735694ENST00000349223+911207_30810351066.0RegionNote=3 X SP repeats
HgeneNFATC3chr16:68225678chr16:89735694ENST00000329524+911207_22310351996.6666666666667RepeatNote=1
HgeneNFATC3chr16:68225678chr16:89735694ENST00000329524+911236_25210351996.6666666666667RepeatNote=2
HgeneNFATC3chr16:68225678chr16:89735694ENST00000329524+911292_30810351996.6666666666667RepeatNote=3
HgeneNFATC3chr16:68225678chr16:89735694ENST00000346183+910207_22310351076.0RepeatNote=1
HgeneNFATC3chr16:68225678chr16:89735694ENST00000346183+910236_25210351076.0RepeatNote=2
HgeneNFATC3chr16:68225678chr16:89735694ENST00000346183+910292_30810351076.0RepeatNote=3
HgeneNFATC3chr16:68225678chr16:89735694ENST00000349223+911207_22310351066.0RepeatNote=1
HgeneNFATC3chr16:68225678chr16:89735694ENST00000349223+911236_25210351066.0RepeatNote=2
HgeneNFATC3chr16:68225678chr16:89735694ENST00000349223+911292_30810351066.0RepeatNote=3

- In-frame and not-retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneNFATC3chr16:68225678chr16:89735694ENST00000329524+9111032_104110351996.6666666666667MotifNote=Nuclear export signal
HgeneNFATC3chr16:68225678chr16:89735694ENST00000346183+9101032_104110351076.0MotifNote=Nuclear export signal
HgeneNFATC3chr16:68225678chr16:89735694ENST00000349223+9111032_104110351066.0MotifNote=Nuclear export signal


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Fusion Gene Sequence for NFATC3-SPATA33


check button For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. To have fusion amino acid sequence, we ran ORFfinder and chose the longest ORF among the all predicted ones.
>58810_58810_1_NFATC3-SPATA33_NFATC3_chr16_68225678_ENST00000329524_SPATA33_chr16_89735694_ENST00000579310_length(transcript)=4142nt_BP=3130nt
GCTGCAGCACCCTGGGCCACGCCGATGACTACTGCAAACTGTGGCGCCCACGACGAGCTCGACTTCAAACTCGTCTTTGGCGAGGACGGG
GCGCCGGCGCCGCCGCCCCCGGGCTCGCGGCCTGCAGATCTTGAGCCAGATGATTGTGCATCCATTTACATCTTTAATGTAGATCCACCT
CCATCTACTTTAACCACACCACTTTGCTTACCACATCATGGATTACCGTCTCACTCTTCTGTTTTGTCACCATCGTTTCAGCTCCAAAGT
CACAAAAACTATGAAGGAACTTGTGAGATTCCTGAATCTAAATATAGCCCATTAGGTGGTCCCAAACCCTTTGAGTGCCCAAGTATTCAA
ATTACATCTATCTCTCCTAACTGTCATCAAGAATTAGATGCACATGAAGATGACCTACAGATAAATGACCCAGAACGGGAATTTTTGGAA
AGGCCTTCTAGAGATCATCTCTATCTTCCTCTTGAGCCATCCTACCGGGAGTCTTCTCTTAGTCCTAGTCCTGCCAGCAGCATCTCTTCT
AGGAGTTGGTTCTCTGATGCATCTTCTTGTGAATCGCTTTCACATATTTATGATGATGTGGACTCAGAGTTGAATGAAGCTGCAGCCCGA
TTTACCCTTGGATCCCCTCTGACTTCTCCTGGTGGCTCTCCAGGGGGCTGCCCTGGAGAAGAAACTTGGCATCAACAGTATGGACTTGGA
CACTCATTATCACCCAGGCAATCTCCTTGCCACTCTCCTAGATCCAGTGTCACTGATGAGAATTGGCTGAGCCCCAGGCCAGCCTCAGGA
CCCTCATCAAGGCCCACATCCCCCTGTGGGAAACGGAGGCACTCCAGTGCTGAAGTTTGTTATGCTGGGTCCCTTTCACCCCATCACTCA
CCTGTTCCTTCACCTGGTCACTCCCCCAGGGGAAGTGTGACAGAAGATACGTGGCTCAATGCTTCTGTCCATGGTGGGTCAGGCCTTGGC
CCTGCAGTTTTTCCATTTCAGTACTGTGTAGAGACTGACATCCCTCTCAAAACAAGGAAAACTTCTGAAGATCAAGCTGCCATACTACCA
GGAAAATTAGAGCTGTGTTCAGATGACCAAGGGAGTTTATCACCAGCCCGGGAGACTTCAATAGATGATGGCCTTGGATCTCAGTATCCT
TTAAAGAAAGATTCATGTGGTGATCAGTTTCTTTCAGTTCCTTCACCCTTTACCTGGAGCAAACCAAAGCCTGGCCACACCCCTATATTT
CGCACATCTTCATTACCTCCACTAGACTGGCCTTTACCAGCTCATTTTGGACAATGTGAACTGAAAATAGAAGTGCAACCTAAAACTCAT
CATCGAGCCCATTATGAAACTGAAGGTAGCCGAGGGGCAGTAAAAGCATCTACTGGGGGACATCCTGTTGTGAAGCTCCTGGGCTATAAC
GAAAAGCCAATAAATCTACAAATGTTTATTGGGACAGCAGATGATCGATATTTACGACCTCATGCATTTTACCAGGTGCATCGAATCACT
GGGAAGACAGTCGCTACTGCAAGCCAAGAGATAATAATTGCCAGTACAAAAGTTCTGGAAATTCCACTTCTTCCTGAAAATAATATGTCA
GCCAGTATTGATTGTGCAGGTATTTTGAAACTCCGCAATTCAGATATAGAACTTCGAAAAGGAGAAACTGATATTGGCAGAAAGAATACT
AGAGTACGACTTGTGTTTCGTGTACACATCCCACAGCCCAGTGGAAAAGTCCTTTCTCTGCAGATAGCCTCTATACCCGTTGAGTGCTCC
CAGCGGTCTGCTCAAGAACTTCCTCATATTGAGAAGTACAGTATCAACAGTTGTTCTGTAAATGGAGGTCATGAAATGGTTGTGACTGGA
TCTAATTTTCTTCCAGAATCCAAAATCATTTTTCTTGAAAAAGGACAAGATGGACGACCTCAGTGGGAGGTAGAAGGGAAGATAATCAGG
GAAAAATGTCAAGGGGCTCACATTGTCCTTGAAGTTCCTCCATATCATAACCCAGCAGTTACAGCTGCAGTGCAGGTGCACTTTTATCTT
TGCAATGGCAAGAGGAAAAAAAGCCAGTCTCAACGTTTTACTTATACACCAGTTTTGATGAAGCAAGAACACAGAGAAGAGATTGATTTG
TCTTCAGTTCCATCTTTGCCTGTGCCTCATCCTGCTCAGACCCAGAGGCCTTCCTCTGATTCAGGGTGTTCACATGACAGTGTACTGTCA
GGACAGAGAAGTTTGATTTGCTCCATCCCACAAACATATGCATCCATGGTGACCTCATCCCATCTGCCACAGTTGCAGTGTAGAGATGAG
AGTGTTAGTAAAGAACAGCATATGATTCCTTCTCCAATTGTACACCAGCCTTTTCAAGTCACACCAACACCTCCTGTGGGGTCTTCCTAT
CAGCCTATGCAAACTAATGTTGTGTACAATGGACCAACTTGTCTTCCTATTAATGCTGCCTCTAGTCAAGAATTTGATTCAGTTTTGTTT
CAGCAGGATGCAACTCTTTCTGGTTTAGTGAATCTTGGCTGTCAACCACTGTCATCCATACCATTTCATTCTTCAAATTCAGGCTCAACA
GGACATCTCTTAGCCCATACACCTCATTCTGTGCATACCCTGCCTCATCTGCAATCAATGGGATATCATTGTTCAAATACAGGACAAAGA
TCTCTTTCTTCTCCAGTGGCTGACCAGATTACAGGTCAGCCTTCGTCTCAGTTACAACCTATTACATATGGTCCTTCACATTCAGGGTCT
GCTACAACAGCTTCCCCAGCAGCTTCTCATCCCTTGGCTAGTTCACCGCTTTCTGGGCCACCATCTCCTCAGCTTCAGCCTATGCCTTAC
CAATCTCCTAGCTCAGGAACTGCCTCATCACCGTCTCCAGCCACCAGAATGCATTCTGGACAGCACTCAACTCAAGCACAAAGTACGGGC
CAGGGGGGTCTTTCTGCACCTTCATCCTTAATATGTCACAGTTTGTGTGATCCAGCGTCATTTCCACCTGATGGGGCAACTGTGAGCATT
AAACCTGAACCAGAAGATCGAGAGCCTAACTTTGCAACCATTGGTCTGCAGGACATCACTTTAGATGATGAGAAACCTGATGTAAAGCAA
AAGTCCAGCAGGAAGAAAGTGGTCGTTCCACAGATCATCATCACGCGAGCGTCGAATGAGACGCTAGTCAGTTGCAGTTCCAGCGGGAGT
GACCAGCAGAGAACCATTCGGGAGCCGGAGGACTGGGGCCCCTACCGGCGGCACAGGAACCCCAGTACAGCAGACGCCTATAATTCACAT
CTCAAAGAATAAACAAGCACCTTTGCATGGCACTCGCTACTCCCTGCGATAGGCGTCTCGGGAACAGCCGCCTCACCCTGTGAGAAGCCG
AGGCCCCTTCTCCAGTGCTCTCGGGGAGGTTGCACCAGGCCCACCCCACCCTGTGAGAAACTGCAGCCCCCTTCTCCAGTGCTTTCGGGG
AGGGTGCACCAGGCCCGCCCCACCTTGTGAGAAGCCGTGGCCCCCTTCTCCAGTGCTCTCAGGGAGGGTGCACCAGGCCTGCCCCCGCCG
TGAGAAACTGCAGTCCCCTTCTCCAGTGCTCTCGGGGAGGGTGCACCAGGCCCACCCCACCCTGTGAGAACCTGCAGCCCCCTTCTCCAA
TGCTCTCGGGGAGGGTACACCAGGGTTGCCCCACCCTGTGAGAAGCCACCGCCCCCTTCTCCAGTGCTCTCGGGGAGGGTGCACCAGGGC
TGCCCCACGCTGTAAGAAGCCGCCGCCCCCTTCTCCAGTGCTCTCCAGCCCGCCCCACCCTGTGAGAAGCCATGGCCCCTTCTCCAGTGC
TTTTGGGGAGGGTGCACCAGGGCCACCCCACCCTGTGAGAAGCCGTGGCCCCCTTCTCCAGTGCTTTCGGGGAGGGTACACCAGGCCCGC
CCCACCCTGTGAGAAGCCGTGGCCCCCTTCTCCCGTGCTCTCAGGGAGGGTGCACCAGGCCTGCCCCCGCCTTGAGAAACTGCAGCCCCC
TTCTCCAGTGCTCTGGGGGAGGGTGCACCAGGCCTGCCCACCCTGTGAGAAACTGCACCCCCTTCTCCAGTGCTCTCGGGGAGGGTGCAC

>58810_58810_1_NFATC3-SPATA33_NFATC3_chr16_68225678_ENST00000329524_SPATA33_chr16_89735694_ENST00000579310_length(amino acids)=1105AA_BP=1035
MTTANCGAHDELDFKLVFGEDGAPAPPPPGSRPADLEPDDCASIYIFNVDPPPSTLTTPLCLPHHGLPSHSSVLSPSFQLQSHKNYEGTC
EIPESKYSPLGGPKPFECPSIQITSISPNCHQELDAHEDDLQINDPEREFLERPSRDHLYLPLEPSYRESSLSPSPASSISSRSWFSDAS
SCESLSHIYDDVDSELNEAAARFTLGSPLTSPGGSPGGCPGEETWHQQYGLGHSLSPRQSPCHSPRSSVTDENWLSPRPASGPSSRPTSP
CGKRRHSSAEVCYAGSLSPHHSPVPSPGHSPRGSVTEDTWLNASVHGGSGLGPAVFPFQYCVETDIPLKTRKTSEDQAAILPGKLELCSD
DQGSLSPARETSIDDGLGSQYPLKKDSCGDQFLSVPSPFTWSKPKPGHTPIFRTSSLPPLDWPLPAHFGQCELKIEVQPKTHHRAHYETE
GSRGAVKASTGGHPVVKLLGYNEKPINLQMFIGTADDRYLRPHAFYQVHRITGKTVATASQEIIIASTKVLEIPLLPENNMSASIDCAGI
LKLRNSDIELRKGETDIGRKNTRVRLVFRVHIPQPSGKVLSLQIASIPVECSQRSAQELPHIEKYSINSCSVNGGHEMVVTGSNFLPESK
IIFLEKGQDGRPQWEVEGKIIREKCQGAHIVLEVPPYHNPAVTAAVQVHFYLCNGKRKKSQSQRFTYTPVLMKQEHREEIDLSSVPSLPV
PHPAQTQRPSSDSGCSHDSVLSGQRSLICSIPQTYASMVTSSHLPQLQCRDESVSKEQHMIPSPIVHQPFQVTPTPPVGSSYQPMQTNVV
YNGPTCLPINAASSQEFDSVLFQQDATLSGLVNLGCQPLSSIPFHSSNSGSTGHLLAHTPHSVHTLPHLQSMGYHCSNTGQRSLSSPVAD
QITGQPSSQLQPITYGPSHSGSATTASPAASHPLASSPLSGPPSPQLQPMPYQSPSSGTASSPSPATRMHSGQHSTQAQSTGQGGLSAPS
SLICHSLCDPASFPPDGATVSIKPEPEDREPNFATIGLQDITLDDEKPDVKQKSSRKKVVVPQIIITRASNETLVSCSSSGSDQQRTIRE

--------------------------------------------------------------
>58810_58810_2_NFATC3-SPATA33_NFATC3_chr16_68225678_ENST00000346183_SPATA33_chr16_89735694_ENST00000579310_length(transcript)=4142nt_BP=3130nt
GCTGCAGCACCCTGGGCCACGCCGATGACTACTGCAAACTGTGGCGCCCACGACGAGCTCGACTTCAAACTCGTCTTTGGCGAGGACGGG
GCGCCGGCGCCGCCGCCCCCGGGCTCGCGGCCTGCAGATCTTGAGCCAGATGATTGTGCATCCATTTACATCTTTAATGTAGATCCACCT
CCATCTACTTTAACCACACCACTTTGCTTACCACATCATGGATTACCGTCTCACTCTTCTGTTTTGTCACCATCGTTTCAGCTCCAAAGT
CACAAAAACTATGAAGGAACTTGTGAGATTCCTGAATCTAAATATAGCCCATTAGGTGGTCCCAAACCCTTTGAGTGCCCAAGTATTCAA
ATTACATCTATCTCTCCTAACTGTCATCAAGAATTAGATGCACATGAAGATGACCTACAGATAAATGACCCAGAACGGGAATTTTTGGAA
AGGCCTTCTAGAGATCATCTCTATCTTCCTCTTGAGCCATCCTACCGGGAGTCTTCTCTTAGTCCTAGTCCTGCCAGCAGCATCTCTTCT
AGGAGTTGGTTCTCTGATGCATCTTCTTGTGAATCGCTTTCACATATTTATGATGATGTGGACTCAGAGTTGAATGAAGCTGCAGCCCGA
TTTACCCTTGGATCCCCTCTGACTTCTCCTGGTGGCTCTCCAGGGGGCTGCCCTGGAGAAGAAACTTGGCATCAACAGTATGGACTTGGA
CACTCATTATCACCCAGGCAATCTCCTTGCCACTCTCCTAGATCCAGTGTCACTGATGAGAATTGGCTGAGCCCCAGGCCAGCCTCAGGA
CCCTCATCAAGGCCCACATCCCCCTGTGGGAAACGGAGGCACTCCAGTGCTGAAGTTTGTTATGCTGGGTCCCTTTCACCCCATCACTCA
CCTGTTCCTTCACCTGGTCACTCCCCCAGGGGAAGTGTGACAGAAGATACGTGGCTCAATGCTTCTGTCCATGGTGGGTCAGGCCTTGGC
CCTGCAGTTTTTCCATTTCAGTACTGTGTAGAGACTGACATCCCTCTCAAAACAAGGAAAACTTCTGAAGATCAAGCTGCCATACTACCA
GGAAAATTAGAGCTGTGTTCAGATGACCAAGGGAGTTTATCACCAGCCCGGGAGACTTCAATAGATGATGGCCTTGGATCTCAGTATCCT
TTAAAGAAAGATTCATGTGGTGATCAGTTTCTTTCAGTTCCTTCACCCTTTACCTGGAGCAAACCAAAGCCTGGCCACACCCCTATATTT
CGCACATCTTCATTACCTCCACTAGACTGGCCTTTACCAGCTCATTTTGGACAATGTGAACTGAAAATAGAAGTGCAACCTAAAACTCAT
CATCGAGCCCATTATGAAACTGAAGGTAGCCGAGGGGCAGTAAAAGCATCTACTGGGGGACATCCTGTTGTGAAGCTCCTGGGCTATAAC
GAAAAGCCAATAAATCTACAAATGTTTATTGGGACAGCAGATGATCGATATTTACGACCTCATGCATTTTACCAGGTGCATCGAATCACT
GGGAAGACAGTCGCTACTGCAAGCCAAGAGATAATAATTGCCAGTACAAAAGTTCTGGAAATTCCACTTCTTCCTGAAAATAATATGTCA
GCCAGTATTGATTGTGCAGGTATTTTGAAACTCCGCAATTCAGATATAGAACTTCGAAAAGGAGAAACTGATATTGGCAGAAAGAATACT
AGAGTACGACTTGTGTTTCGTGTACACATCCCACAGCCCAGTGGAAAAGTCCTTTCTCTGCAGATAGCCTCTATACCCGTTGAGTGCTCC
CAGCGGTCTGCTCAAGAACTTCCTCATATTGAGAAGTACAGTATCAACAGTTGTTCTGTAAATGGAGGTCATGAAATGGTTGTGACTGGA
TCTAATTTTCTTCCAGAATCCAAAATCATTTTTCTTGAAAAAGGACAAGATGGACGACCTCAGTGGGAGGTAGAAGGGAAGATAATCAGG
GAAAAATGTCAAGGGGCTCACATTGTCCTTGAAGTTCCTCCATATCATAACCCAGCAGTTACAGCTGCAGTGCAGGTGCACTTTTATCTT
TGCAATGGCAAGAGGAAAAAAAGCCAGTCTCAACGTTTTACTTATACACCAGTTTTGATGAAGCAAGAACACAGAGAAGAGATTGATTTG
TCTTCAGTTCCATCTTTGCCTGTGCCTCATCCTGCTCAGACCCAGAGGCCTTCCTCTGATTCAGGGTGTTCACATGACAGTGTACTGTCA
GGACAGAGAAGTTTGATTTGCTCCATCCCACAAACATATGCATCCATGGTGACCTCATCCCATCTGCCACAGTTGCAGTGTAGAGATGAG
AGTGTTAGTAAAGAACAGCATATGATTCCTTCTCCAATTGTACACCAGCCTTTTCAAGTCACACCAACACCTCCTGTGGGGTCTTCCTAT
CAGCCTATGCAAACTAATGTTGTGTACAATGGACCAACTTGTCTTCCTATTAATGCTGCCTCTAGTCAAGAATTTGATTCAGTTTTGTTT
CAGCAGGATGCAACTCTTTCTGGTTTAGTGAATCTTGGCTGTCAACCACTGTCATCCATACCATTTCATTCTTCAAATTCAGGCTCAACA
GGACATCTCTTAGCCCATACACCTCATTCTGTGCATACCCTGCCTCATCTGCAATCAATGGGATATCATTGTTCAAATACAGGACAAAGA
TCTCTTTCTTCTCCAGTGGCTGACCAGATTACAGGTCAGCCTTCGTCTCAGTTACAACCTATTACATATGGTCCTTCACATTCAGGGTCT
GCTACAACAGCTTCCCCAGCAGCTTCTCATCCCTTGGCTAGTTCACCGCTTTCTGGGCCACCATCTCCTCAGCTTCAGCCTATGCCTTAC
CAATCTCCTAGCTCAGGAACTGCCTCATCACCGTCTCCAGCCACCAGAATGCATTCTGGACAGCACTCAACTCAAGCACAAAGTACGGGC
CAGGGGGGTCTTTCTGCACCTTCATCCTTAATATGTCACAGTTTGTGTGATCCAGCGTCATTTCCACCTGATGGGGCAACTGTGAGCATT
AAACCTGAACCAGAAGATCGAGAGCCTAACTTTGCAACCATTGGTCTGCAGGACATCACTTTAGATGATGAGAAACCTGATGTAAAGCAA
AAGTCCAGCAGGAAGAAAGTGGTCGTTCCACAGATCATCATCACGCGAGCGTCGAATGAGACGCTAGTCAGTTGCAGTTCCAGCGGGAGT
GACCAGCAGAGAACCATTCGGGAGCCGGAGGACTGGGGCCCCTACCGGCGGCACAGGAACCCCAGTACAGCAGACGCCTATAATTCACAT
CTCAAAGAATAAACAAGCACCTTTGCATGGCACTCGCTACTCCCTGCGATAGGCGTCTCGGGAACAGCCGCCTCACCCTGTGAGAAGCCG
AGGCCCCTTCTCCAGTGCTCTCGGGGAGGTTGCACCAGGCCCACCCCACCCTGTGAGAAACTGCAGCCCCCTTCTCCAGTGCTTTCGGGG
AGGGTGCACCAGGCCCGCCCCACCTTGTGAGAAGCCGTGGCCCCCTTCTCCAGTGCTCTCAGGGAGGGTGCACCAGGCCTGCCCCCGCCG
TGAGAAACTGCAGTCCCCTTCTCCAGTGCTCTCGGGGAGGGTGCACCAGGCCCACCCCACCCTGTGAGAACCTGCAGCCCCCTTCTCCAA
TGCTCTCGGGGAGGGTACACCAGGGTTGCCCCACCCTGTGAGAAGCCACCGCCCCCTTCTCCAGTGCTCTCGGGGAGGGTGCACCAGGGC
TGCCCCACGCTGTAAGAAGCCGCCGCCCCCTTCTCCAGTGCTCTCCAGCCCGCCCCACCCTGTGAGAAGCCATGGCCCCTTCTCCAGTGC
TTTTGGGGAGGGTGCACCAGGGCCACCCCACCCTGTGAGAAGCCGTGGCCCCCTTCTCCAGTGCTTTCGGGGAGGGTACACCAGGCCCGC
CCCACCCTGTGAGAAGCCGTGGCCCCCTTCTCCCGTGCTCTCAGGGAGGGTGCACCAGGCCTGCCCCCGCCTTGAGAAACTGCAGCCCCC
TTCTCCAGTGCTCTGGGGGAGGGTGCACCAGGCCTGCCCACCCTGTGAGAAACTGCACCCCCTTCTCCAGTGCTCTCGGGGAGGGTGCAC

>58810_58810_2_NFATC3-SPATA33_NFATC3_chr16_68225678_ENST00000346183_SPATA33_chr16_89735694_ENST00000579310_length(amino acids)=1105AA_BP=1035
MTTANCGAHDELDFKLVFGEDGAPAPPPPGSRPADLEPDDCASIYIFNVDPPPSTLTTPLCLPHHGLPSHSSVLSPSFQLQSHKNYEGTC
EIPESKYSPLGGPKPFECPSIQITSISPNCHQELDAHEDDLQINDPEREFLERPSRDHLYLPLEPSYRESSLSPSPASSISSRSWFSDAS
SCESLSHIYDDVDSELNEAAARFTLGSPLTSPGGSPGGCPGEETWHQQYGLGHSLSPRQSPCHSPRSSVTDENWLSPRPASGPSSRPTSP
CGKRRHSSAEVCYAGSLSPHHSPVPSPGHSPRGSVTEDTWLNASVHGGSGLGPAVFPFQYCVETDIPLKTRKTSEDQAAILPGKLELCSD
DQGSLSPARETSIDDGLGSQYPLKKDSCGDQFLSVPSPFTWSKPKPGHTPIFRTSSLPPLDWPLPAHFGQCELKIEVQPKTHHRAHYETE
GSRGAVKASTGGHPVVKLLGYNEKPINLQMFIGTADDRYLRPHAFYQVHRITGKTVATASQEIIIASTKVLEIPLLPENNMSASIDCAGI
LKLRNSDIELRKGETDIGRKNTRVRLVFRVHIPQPSGKVLSLQIASIPVECSQRSAQELPHIEKYSINSCSVNGGHEMVVTGSNFLPESK
IIFLEKGQDGRPQWEVEGKIIREKCQGAHIVLEVPPYHNPAVTAAVQVHFYLCNGKRKKSQSQRFTYTPVLMKQEHREEIDLSSVPSLPV
PHPAQTQRPSSDSGCSHDSVLSGQRSLICSIPQTYASMVTSSHLPQLQCRDESVSKEQHMIPSPIVHQPFQVTPTPPVGSSYQPMQTNVV
YNGPTCLPINAASSQEFDSVLFQQDATLSGLVNLGCQPLSSIPFHSSNSGSTGHLLAHTPHSVHTLPHLQSMGYHCSNTGQRSLSSPVAD
QITGQPSSQLQPITYGPSHSGSATTASPAASHPLASSPLSGPPSPQLQPMPYQSPSSGTASSPSPATRMHSGQHSTQAQSTGQGGLSAPS
SLICHSLCDPASFPPDGATVSIKPEPEDREPNFATIGLQDITLDDEKPDVKQKSSRKKVVVPQIIITRASNETLVSCSSSGSDQQRTIRE

--------------------------------------------------------------
>58810_58810_3_NFATC3-SPATA33_NFATC3_chr16_68225678_ENST00000349223_SPATA33_chr16_89735694_ENST00000579310_length(transcript)=4342nt_BP=3330nt
GCACCGGTGGCGGGCGGCTGCGGTTCCTGGTGCTGCTCGGCGCGCGGCCAGCTTTCGGAACGGAACGCTCGGCGTCGCGGGCCCCGCCCG
GAAAGTTTGCCGTGGAGTCGCGACCTCTTGGCCCGCGCGGCCCGGCATGAAGCGGCGTTGAGGAGCTGCTGCCGCCGCTTGCCGCTGCCG
CCGCCGCCGCCTGAGGAGGAGCTGCAGCACCCTGGGCCACGCCGATGACTACTGCAAACTGTGGCGCCCACGACGAGCTCGACTTCAAAC
TCGTCTTTGGCGAGGACGGGGCGCCGGCGCCGCCGCCCCCGGGCTCGCGGCCTGCAGATCTTGAGCCAGATGATTGTGCATCCATTTACA
TCTTTAATGTAGATCCACCTCCATCTACTTTAACCACACCACTTTGCTTACCACATCATGGATTACCGTCTCACTCTTCTGTTTTGTCAC
CATCGTTTCAGCTCCAAAGTCACAAAAACTATGAAGGAACTTGTGAGATTCCTGAATCTAAATATAGCCCATTAGGTGGTCCCAAACCCT
TTGAGTGCCCAAGTATTCAAATTACATCTATCTCTCCTAACTGTCATCAAGAATTAGATGCACATGAAGATGACCTACAGATAAATGACC
CAGAACGGGAATTTTTGGAAAGGCCTTCTAGAGATCATCTCTATCTTCCTCTTGAGCCATCCTACCGGGAGTCTTCTCTTAGTCCTAGTC
CTGCCAGCAGCATCTCTTCTAGGAGTTGGTTCTCTGATGCATCTTCTTGTGAATCGCTTTCACATATTTATGATGATGTGGACTCAGAGT
TGAATGAAGCTGCAGCCCGATTTACCCTTGGATCCCCTCTGACTTCTCCTGGTGGCTCTCCAGGGGGCTGCCCTGGAGAAGAAACTTGGC
ATCAACAGTATGGACTTGGACACTCATTATCACCCAGGCAATCTCCTTGCCACTCTCCTAGATCCAGTGTCACTGATGAGAATTGGCTGA
GCCCCAGGCCAGCCTCAGGACCCTCATCAAGGCCCACATCCCCCTGTGGGAAACGGAGGCACTCCAGTGCTGAAGTTTGTTATGCTGGGT
CCCTTTCACCCCATCACTCACCTGTTCCTTCACCTGGTCACTCCCCCAGGGGAAGTGTGACAGAAGATACGTGGCTCAATGCTTCTGTCC
ATGGTGGGTCAGGCCTTGGCCCTGCAGTTTTTCCATTTCAGTACTGTGTAGAGACTGACATCCCTCTCAAAACAAGGAAAACTTCTGAAG
ATCAAGCTGCCATACTACCAGGAAAATTAGAGCTGTGTTCAGATGACCAAGGGAGTTTATCACCAGCCCGGGAGACTTCAATAGATGATG
GCCTTGGATCTCAGTATCCTTTAAAGAAAGATTCATGTGGTGATCAGTTTCTTTCAGTTCCTTCACCCTTTACCTGGAGCAAACCAAAGC
CTGGCCACACCCCTATATTTCGCACATCTTCATTACCTCCACTAGACTGGCCTTTACCAGCTCATTTTGGACAATGTGAACTGAAAATAG
AAGTGCAACCTAAAACTCATCATCGAGCCCATTATGAAACTGAAGGTAGCCGAGGGGCAGTAAAAGCATCTACTGGGGGACATCCTGTTG
TGAAGCTCCTGGGCTATAACGAAAAGCCAATAAATCTACAAATGTTTATTGGGACAGCAGATGATCGATATTTACGACCTCATGCATTTT
ACCAGGTGCATCGAATCACTGGGAAGACAGTCGCTACTGCAAGCCAAGAGATAATAATTGCCAGTACAAAAGTTCTGGAAATTCCACTTC
TTCCTGAAAATAATATGTCAGCCAGTATTGATTGTGCAGGTATTTTGAAACTCCGCAATTCAGATATAGAACTTCGAAAAGGAGAAACTG
ATATTGGCAGAAAGAATACTAGAGTACGACTTGTGTTTCGTGTACACATCCCACAGCCCAGTGGAAAAGTCCTTTCTCTGCAGATAGCCT
CTATACCCGTTGAGTGCTCCCAGCGGTCTGCTCAAGAACTTCCTCATATTGAGAAGTACAGTATCAACAGTTGTTCTGTAAATGGAGGTC
ATGAAATGGTTGTGACTGGATCTAATTTTCTTCCAGAATCCAAAATCATTTTTCTTGAAAAAGGACAAGATGGACGACCTCAGTGGGAGG
TAGAAGGGAAGATAATCAGGGAAAAATGTCAAGGGGCTCACATTGTCCTTGAAGTTCCTCCATATCATAACCCAGCAGTTACAGCTGCAG
TGCAGGTGCACTTTTATCTTTGCAATGGCAAGAGGAAAAAAAGCCAGTCTCAACGTTTTACTTATACACCAGTTTTGATGAAGCAAGAAC
ACAGAGAAGAGATTGATTTGTCTTCAGTTCCATCTTTGCCTGTGCCTCATCCTGCTCAGACCCAGAGGCCTTCCTCTGATTCAGGGTGTT
CACATGACAGTGTACTGTCAGGACAGAGAAGTTTGATTTGCTCCATCCCACAAACATATGCATCCATGGTGACCTCATCCCATCTGCCAC
AGTTGCAGTGTAGAGATGAGAGTGTTAGTAAAGAACAGCATATGATTCCTTCTCCAATTGTACACCAGCCTTTTCAAGTCACACCAACAC
CTCCTGTGGGGTCTTCCTATCAGCCTATGCAAACTAATGTTGTGTACAATGGACCAACTTGTCTTCCTATTAATGCTGCCTCTAGTCAAG
AATTTGATTCAGTTTTGTTTCAGCAGGATGCAACTCTTTCTGGTTTAGTGAATCTTGGCTGTCAACCACTGTCATCCATACCATTTCATT
CTTCAAATTCAGGCTCAACAGGACATCTCTTAGCCCATACACCTCATTCTGTGCATACCCTGCCTCATCTGCAATCAATGGGATATCATT
GTTCAAATACAGGACAAAGATCTCTTTCTTCTCCAGTGGCTGACCAGATTACAGGTCAGCCTTCGTCTCAGTTACAACCTATTACATATG
GTCCTTCACATTCAGGGTCTGCTACAACAGCTTCCCCAGCAGCTTCTCATCCCTTGGCTAGTTCACCGCTTTCTGGGCCACCATCTCCTC
AGCTTCAGCCTATGCCTTACCAATCTCCTAGCTCAGGAACTGCCTCATCACCGTCTCCAGCCACCAGAATGCATTCTGGACAGCACTCAA
CTCAAGCACAAAGTACGGGCCAGGGGGGTCTTTCTGCACCTTCATCCTTAATATGTCACAGTTTGTGTGATCCAGCGTCATTTCCACCTG
ATGGGGCAACTGTGAGCATTAAACCTGAACCAGAAGATCGAGAGCCTAACTTTGCAACCATTGGTCTGCAGGACATCACTTTAGATGATG
AGAAACCTGATGTAAAGCAAAAGTCCAGCAGGAAGAAAGTGGTCGTTCCACAGATCATCATCACGCGAGCGTCGAATGAGACGCTAGTCA
GTTGCAGTTCCAGCGGGAGTGACCAGCAGAGAACCATTCGGGAGCCGGAGGACTGGGGCCCCTACCGGCGGCACAGGAACCCCAGTACAG
CAGACGCCTATAATTCACATCTCAAAGAATAAACAAGCACCTTTGCATGGCACTCGCTACTCCCTGCGATAGGCGTCTCGGGAACAGCCG
CCTCACCCTGTGAGAAGCCGAGGCCCCTTCTCCAGTGCTCTCGGGGAGGTTGCACCAGGCCCACCCCACCCTGTGAGAAACTGCAGCCCC
CTTCTCCAGTGCTTTCGGGGAGGGTGCACCAGGCCCGCCCCACCTTGTGAGAAGCCGTGGCCCCCTTCTCCAGTGCTCTCAGGGAGGGTG
CACCAGGCCTGCCCCCGCCGTGAGAAACTGCAGTCCCCTTCTCCAGTGCTCTCGGGGAGGGTGCACCAGGCCCACCCCACCCTGTGAGAA
CCTGCAGCCCCCTTCTCCAATGCTCTCGGGGAGGGTACACCAGGGTTGCCCCACCCTGTGAGAAGCCACCGCCCCCTTCTCCAGTGCTCT
CGGGGAGGGTGCACCAGGGCTGCCCCACGCTGTAAGAAGCCGCCGCCCCCTTCTCCAGTGCTCTCCAGCCCGCCCCACCCTGTGAGAAGC
CATGGCCCCTTCTCCAGTGCTTTTGGGGAGGGTGCACCAGGGCCACCCCACCCTGTGAGAAGCCGTGGCCCCCTTCTCCAGTGCTTTCGG
GGAGGGTACACCAGGCCCGCCCCACCCTGTGAGAAGCCGTGGCCCCCTTCTCCCGTGCTCTCAGGGAGGGTGCACCAGGCCTGCCCCCGC
CTTGAGAAACTGCAGCCCCCTTCTCCAGTGCTCTGGGGGAGGGTGCACCAGGCCTGCCCACCCTGTGAGAAACTGCACCCCCTTCTCCAG

>58810_58810_3_NFATC3-SPATA33_NFATC3_chr16_68225678_ENST00000349223_SPATA33_chr16_89735694_ENST00000579310_length(amino acids)=1105AA_BP=1035
MTTANCGAHDELDFKLVFGEDGAPAPPPPGSRPADLEPDDCASIYIFNVDPPPSTLTTPLCLPHHGLPSHSSVLSPSFQLQSHKNYEGTC
EIPESKYSPLGGPKPFECPSIQITSISPNCHQELDAHEDDLQINDPEREFLERPSRDHLYLPLEPSYRESSLSPSPASSISSRSWFSDAS
SCESLSHIYDDVDSELNEAAARFTLGSPLTSPGGSPGGCPGEETWHQQYGLGHSLSPRQSPCHSPRSSVTDENWLSPRPASGPSSRPTSP
CGKRRHSSAEVCYAGSLSPHHSPVPSPGHSPRGSVTEDTWLNASVHGGSGLGPAVFPFQYCVETDIPLKTRKTSEDQAAILPGKLELCSD
DQGSLSPARETSIDDGLGSQYPLKKDSCGDQFLSVPSPFTWSKPKPGHTPIFRTSSLPPLDWPLPAHFGQCELKIEVQPKTHHRAHYETE
GSRGAVKASTGGHPVVKLLGYNEKPINLQMFIGTADDRYLRPHAFYQVHRITGKTVATASQEIIIASTKVLEIPLLPENNMSASIDCAGI
LKLRNSDIELRKGETDIGRKNTRVRLVFRVHIPQPSGKVLSLQIASIPVECSQRSAQELPHIEKYSINSCSVNGGHEMVVTGSNFLPESK
IIFLEKGQDGRPQWEVEGKIIREKCQGAHIVLEVPPYHNPAVTAAVQVHFYLCNGKRKKSQSQRFTYTPVLMKQEHREEIDLSSVPSLPV
PHPAQTQRPSSDSGCSHDSVLSGQRSLICSIPQTYASMVTSSHLPQLQCRDESVSKEQHMIPSPIVHQPFQVTPTPPVGSSYQPMQTNVV
YNGPTCLPINAASSQEFDSVLFQQDATLSGLVNLGCQPLSSIPFHSSNSGSTGHLLAHTPHSVHTLPHLQSMGYHCSNTGQRSLSSPVAD
QITGQPSSQLQPITYGPSHSGSATTASPAASHPLASSPLSGPPSPQLQPMPYQSPSSGTASSPSPATRMHSGQHSTQAQSTGQGGLSAPS
SLICHSLCDPASFPPDGATVSIKPEPEDREPNFATIGLQDITLDDEKPDVKQKSSRKKVVVPQIIITRASNETLVSCSSSGSDQQRTIRE

--------------------------------------------------------------
>58810_58810_4_NFATC3-SPATA33_NFATC3_chr16_68225678_ENST00000575270_SPATA33_chr16_89735694_ENST00000579310_length(transcript)=4456nt_BP=3444nt
GTAGGGGGCGGGGCCGGGCGCGCGGCAGGGCGCGAGAGCGCACCCGCGGCGGCGGTGGCGGCGACTGTGGGGGGGCGGCGGGGAACATTG
GCTAAGCCGACAGTGGAGGCTTAGGCACCGGTGGCGGGCGGCTGCGGTTCCTGGTGCTGCTCGGCGCGCGGCCAGCTTTCGGAACGGAAC
GCTCGGCGTCGCGGGCCCCGCCCGGAAAGTTTGCCGTGGAGTCGCGACCTCTTGGCCCGCGCGGCCCGGCATGAAGCGGCGTTGAGGAGC
TGCTGCCGCCGCTTGCCGCTGCCGCCGCCGCCGCCTGAGGAGGAGCTGCAGCACCCTGGGCCACGCCGATGACTACTGCAAACTGTGGCG
CCCACGACGAGCTCGACTTCAAACTCGTCTTTGGCGAGGACGGGGCGCCGGCGCCGCCGCCCCCGGGCTCGCGGCCTGCAGATCTTGAGC
CAGATGATTGTGCATCCATTTACATCTTTAATGTAGATCCACCTCCATCTACTTTAACCACACCACTTTGCTTACCACATCATGGATTAC
CGTCTCACTCTTCTGTTTTGTCACCATCGTTTCAGCTCCAAAGTCACAAAAACTATGAAGGAACTTGTGAGATTCCTGAATCTAAATATA
GCCCATTAGGTGGTCCCAAACCCTTTGAGTGCCCAAGTATTCAAATTACATCTATCTCTCCTAACTGTCATCAAGAATTAGATGCACATG
AAGATGACCTACAGATAAATGACCCAGAACGGGAATTTTTGGAAAGGCCTTCTAGAGATCATCTCTATCTTCCTCTTGAGCCATCCTACC
GGGAGTCTTCTCTTAGTCCTAGTCCTGCCAGCAGCATCTCTTCTAGGAGTTGGTTCTCTGATGCATCTTCTTGTGAATCGCTTTCACATA
TTTATGATGATGTGGACTCAGAGTTGAATGAAGCTGCAGCCCGATTTACCCTTGGATCCCCTCTGACTTCTCCTGGTGGCTCTCCAGGGG
GCTGCCCTGGAGAAGAAACTTGGCATCAACAGTATGGACTTGGACACTCATTATCACCCAGGCAATCTCCTTGCCACTCTCCTAGATCCA
GTGTCACTGATGAGAATTGGCTGAGCCCCAGGCCAGCCTCAGGACCCTCATCAAGGCCCACATCCCCCTGTGGGAAACGGAGGCACTCCA
GTGCTGAAGTTTGTTATGCTGGGTCCCTTTCACCCCATCACTCACCTGTTCCTTCACCTGGTCACTCCCCCAGGGGAAGTGTGACAGAAG
ATACGTGGCTCAATGCTTCTGTCCATGGTGGGTCAGGCCTTGGCCCTGCAGTTTTTCCATTTCAGTACTGTGTAGAGACTGACATCCCTC
TCAAAACAAGGAAAACTTCTGAAGATCAAGCTGCCATACTACCAGGAAAATTAGAGCTGTGTTCAGATGACCAAGGGAGTTTATCACCAG
CCCGGGAGACTTCAATAGATGATGGCCTTGGATCTCAGTATCCTTTAAAGAAAGATTCATGTGGTGATCAGTTTCTTTCAGTTCCTTCAC
CCTTTACCTGGAGCAAACCAAAGCCTGGCCACACCCCTATATTTCGCACATCTTCATTACCTCCACTAGACTGGCCTTTACCAGCTCATT
TTGGACAATGTGAACTGAAAATAGAAGTGCAACCTAAAACTCATCATCGAGCCCATTATGAAACTGAAGGTAGCCGAGGGGCAGTAAAAG
CATCTACTGGGGGACATCCTGTTGTGAAGCTCCTGGGCTATAACGAAAAGCCAATAAATCTACAAATGTTTATTGGGACAGCAGATGATC
GATATTTACGACCTCATGCATTTTACCAGGTGCATCGAATCACTGGGAAGACAGTCGCTACTGCAAGCCAAGAGATAATAATTGCCAGTA
CAAAAGTTCTGGAAATTCCACTTCTTCCTGAAAATAATATGTCAGCCAGTATTGATTGTGCAGGTATTTTGAAACTCCGCAATTCAGATA
TAGAACTTCGAAAAGGAGAAACTGATATTGGCAGAAAGAATACTAGAGTACGACTTGTGTTTCGTGTACACATCCCACAGCCCAGTGGAA
AAGTCCTTTCTCTGCAGATAGCCTCTATACCCGTTGAGTGCTCCCAGCGGTCTGCTCAAGAACTTCCTCATATTGAGAAGTACAGTATCA
ACAGTTGTTCTGTAAATGGAGGTCATGAAATGGTTGTGACTGGATCTAATTTTCTTCCAGAATCCAAAATCATTTTTCTTGAAAAAGGAC
AAGATGGACGACCTCAGTGGGAGGTAGAAGGGAAGATAATCAGGGAAAAATGTCAAGGGGCTCACATTGTCCTTGAAGTTCCTCCATATC
ATAACCCAGCAGTTACAGCTGCAGTGCAGGTGCACTTTTATCTTTGCAATGGCAAGAGGAAAAAAAGCCAGTCTCAACGTTTTACTTATA
CACCAGTTTTGATGAAGCAAGAACACAGAGAAGAGATTGATTTGTCTTCAGTTCCATCTTTGCCTGTGCCTCATCCTGCTCAGACCCAGA
GGCCTTCCTCTGATTCAGGGTGTTCACATGACAGTGTACTGTCAGGACAGAGAAGTTTGATTTGCTCCATCCCACAAACATATGCATCCA
TGGTGACCTCATCCCATCTGCCACAGTTGCAGTGTAGAGATGAGAGTGTTAGTAAAGAACAGCATATGATTCCTTCTCCAATTGTACACC
AGCCTTTTCAAGTCACACCAACACCTCCTGTGGGGTCTTCCTATCAGCCTATGCAAACTAATGTTGTGTACAATGGACCAACTTGTCTTC
CTATTAATGCTGCCTCTAGTCAAGAATTTGATTCAGTTTTGTTTCAGCAGGATGCAACTCTTTCTGGTTTAGTGAATCTTGGCTGTCAAC
CACTGTCATCCATACCATTTCATTCTTCAAATTCAGGCTCAACAGGACATCTCTTAGCCCATACACCTCATTCTGTGCATACCCTGCCTC
ATCTGCAATCAATGGGATATCATTGTTCAAATACAGGACAAAGATCTCTTTCTTCTCCAGTGGCTGACCAGATTACAGGTCAGCCTTCGT
CTCAGTTACAACCTATTACATATGGTCCTTCACATTCAGGGTCTGCTACAACAGCTTCCCCAGCAGCTTCTCATCCCTTGGCTAGTTCAC
CGCTTTCTGGGCCACCATCTCCTCAGCTTCAGCCTATGCCTTACCAATCTCCTAGCTCAGGAACTGCCTCATCACCGTCTCCAGCCACCA
GAATGCATTCTGGACAGCACTCAACTCAAGCACAAAGTACGGGCCAGGGGGGTCTTTCTGCACCTTCATCCTTAATATGTCACAGTTTGT
GTGATCCAGCGTCATTTCCACCTGATGGGGCAACTGTGAGCATTAAACCTGAACCAGAAGATCGAGAGCCTAACTTTGCAACCATTGGTC
TGCAGGACATCACTTTAGATGATGAGAAACCTGATGTAAAGCAAAAGTCCAGCAGGAAGAAAGTGGTCGTTCCACAGATCATCATCACGC
GAGCGTCGAATGAGACGCTAGTCAGTTGCAGTTCCAGCGGGAGTGACCAGCAGAGAACCATTCGGGAGCCGGAGGACTGGGGCCCCTACC
GGCGGCACAGGAACCCCAGTACAGCAGACGCCTATAATTCACATCTCAAAGAATAAACAAGCACCTTTGCATGGCACTCGCTACTCCCTG
CGATAGGCGTCTCGGGAACAGCCGCCTCACCCTGTGAGAAGCCGAGGCCCCTTCTCCAGTGCTCTCGGGGAGGTTGCACCAGGCCCACCC
CACCCTGTGAGAAACTGCAGCCCCCTTCTCCAGTGCTTTCGGGGAGGGTGCACCAGGCCCGCCCCACCTTGTGAGAAGCCGTGGCCCCCT
TCTCCAGTGCTCTCAGGGAGGGTGCACCAGGCCTGCCCCCGCCGTGAGAAACTGCAGTCCCCTTCTCCAGTGCTCTCGGGGAGGGTGCAC
CAGGCCCACCCCACCCTGTGAGAACCTGCAGCCCCCTTCTCCAATGCTCTCGGGGAGGGTACACCAGGGTTGCCCCACCCTGTGAGAAGC
CACCGCCCCCTTCTCCAGTGCTCTCGGGGAGGGTGCACCAGGGCTGCCCCACGCTGTAAGAAGCCGCCGCCCCCTTCTCCAGTGCTCTCC
AGCCCGCCCCACCCTGTGAGAAGCCATGGCCCCTTCTCCAGTGCTTTTGGGGAGGGTGCACCAGGGCCACCCCACCCTGTGAGAAGCCGT
GGCCCCCTTCTCCAGTGCTTTCGGGGAGGGTACACCAGGCCCGCCCCACCCTGTGAGAAGCCGTGGCCCCCTTCTCCCGTGCTCTCAGGG
AGGGTGCACCAGGCCTGCCCCCGCCTTGAGAAACTGCAGCCCCCTTCTCCAGTGCTCTGGGGGAGGGTGCACCAGGCCTGCCCACCCTGT

>58810_58810_4_NFATC3-SPATA33_NFATC3_chr16_68225678_ENST00000575270_SPATA33_chr16_89735694_ENST00000579310_length(amino acids)=1105AA_BP=1035
MTTANCGAHDELDFKLVFGEDGAPAPPPPGSRPADLEPDDCASIYIFNVDPPPSTLTTPLCLPHHGLPSHSSVLSPSFQLQSHKNYEGTC
EIPESKYSPLGGPKPFECPSIQITSISPNCHQELDAHEDDLQINDPEREFLERPSRDHLYLPLEPSYRESSLSPSPASSISSRSWFSDAS
SCESLSHIYDDVDSELNEAAARFTLGSPLTSPGGSPGGCPGEETWHQQYGLGHSLSPRQSPCHSPRSSVTDENWLSPRPASGPSSRPTSP
CGKRRHSSAEVCYAGSLSPHHSPVPSPGHSPRGSVTEDTWLNASVHGGSGLGPAVFPFQYCVETDIPLKTRKTSEDQAAILPGKLELCSD
DQGSLSPARETSIDDGLGSQYPLKKDSCGDQFLSVPSPFTWSKPKPGHTPIFRTSSLPPLDWPLPAHFGQCELKIEVQPKTHHRAHYETE
GSRGAVKASTGGHPVVKLLGYNEKPINLQMFIGTADDRYLRPHAFYQVHRITGKTVATASQEIIIASTKVLEIPLLPENNMSASIDCAGI
LKLRNSDIELRKGETDIGRKNTRVRLVFRVHIPQPSGKVLSLQIASIPVECSQRSAQELPHIEKYSINSCSVNGGHEMVVTGSNFLPESK
IIFLEKGQDGRPQWEVEGKIIREKCQGAHIVLEVPPYHNPAVTAAVQVHFYLCNGKRKKSQSQRFTYTPVLMKQEHREEIDLSSVPSLPV
PHPAQTQRPSSDSGCSHDSVLSGQRSLICSIPQTYASMVTSSHLPQLQCRDESVSKEQHMIPSPIVHQPFQVTPTPPVGSSYQPMQTNVV
YNGPTCLPINAASSQEFDSVLFQQDATLSGLVNLGCQPLSSIPFHSSNSGSTGHLLAHTPHSVHTLPHLQSMGYHCSNTGQRSLSSPVAD
QITGQPSSQLQPITYGPSHSGSATTASPAASHPLASSPLSGPPSPQLQPMPYQSPSSGTASSPSPATRMHSGQHSTQAQSTGQGGLSAPS
SLICHSLCDPASFPPDGATVSIKPEPEDREPNFATIGLQDITLDDEKPDVKQKSSRKKVVVPQIIITRASNETLVSCSSSGSDQQRTIRE

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Fusion Gene PPI Analysis for NFATC3-SPATA33


check button Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in

ChiPPI page.


check button Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160)
HgeneHgene's interactorsTgeneTgene's interactors


check button - Retained PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenStill interaction with


check button - Lost PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


check button - Retained PPIs, but lost function due to frame-shift fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


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Related Drugs for NFATC3-SPATA33


check button Drugs targeting genes involved in this fusion gene.
(DrugBank Version 5.1.8 2021-05-08)
PartnerGeneUniProtAccDrugBank IDDrug nameDrug activityDrug typeDrug status

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Related Diseases for NFATC3-SPATA33


check button Diseases associated with fusion partners.
(DisGeNet 4.0)
PartnerGeneDisease IDDisease name# pubmedsSource