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Center for Computational Systems Medicine
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Fusion Gene Summary

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Fusion Gene ORF analysis

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Fusion Genomic Features

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Fusion Protein Features

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Fusion Gene Sequence

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Fusion Gene PPI analysis

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Related Drugs

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Related Diseases

Fusion gene:NINL-NAA20 (FusionGDB2 ID:59154)

Fusion Gene Summary for NINL-NAA20

check button Fusion gene summary
Fusion gene informationFusion gene name: NINL-NAA20
Fusion gene ID: 59154
HgeneTgene
Gene symbol

NINL

NAA20

Gene ID

22981

51126

Gene nameninein likeN-alpha-acetyltransferase 20, NatB catalytic subunit
SynonymsNLPNAT3|NAT3P|NAT5|NAT5P|dJ1002M8.1
Cytomap

20p11.21

20p11.23

Type of geneprotein-codingprotein-coding
Descriptionninein-like proteinN-alpha-acetyltransferase 20N-acetyltransferase 3 homologN-acetyltransferase 5 (ARD1 homolog, S. cerevisiae)N-acetyltransferase 5 (GCN5-related, putative)N-acetyltransferase 5, ARD1 subunit (arrest-defective 1, S. cerevisiae, homolog)N-terminal acety
Modification date2020031320200320
UniProtAcc

Q9Y2I6

P61599

Ensembl transtripts involved in fusion geneENST00000278886, ENST00000422516, 
ENST00000464285, 		ENST00000310450, 
ENST00000398602, ENST00000484480, 
ENST00000334982, 
Fusion gene scores* DoF score6 X 6 X 6=2163 X 4 X 2=24
# samples 84
** MAII scorelog2(8/216*10)=-1.43295940727611
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0		log2(4/24*10)=0.736965594166206
effective Gene in Pan-Cancer Fusion Genes (eGinPCFGs).
DoF>8 and MAII>0
Context

PubMed: NINL [Title/Abstract] AND NAA20 [Title/Abstract] AND fusion [Title/Abstract]

Most frequent breakpointNINL(25507044)-NAA20(20007428), # samples:3
Anticipated loss of major functional domain due to fusion event.
* DoF score (Degree of Frequency) = # partners X # break points X # cancer types
** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)

check button Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez
PartnerGeneGO IDGO termPubMed ID

check buttonFusion gene breakpoints across NINL (5'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check buttonFusion gene breakpoints across NAA20 (3'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check button Fusion gene information from two resources (ChiTars 5.0 and ChimerDB 4.0)
* All genome coordinats were lifted-over on hg19.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
SourceDiseaseSampleHgeneHchrHbpHstrandTgeneTchrTbpTstrand
ChimerDB4PRADTCGA-G9-6351-01ANINLchr20

25507044

-NAA20chr20

20007428

+
ChimerDB4PRADTCGA-G9-6351NINLchr20

25507043

-NAA20chr20

20007427

+
ChimerDB4PRADTCGA-G9-6351NINLchr20

25507044

-NAA20chr20

20007428

+


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Fusion Gene ORF analysis for NINL-NAA20

check button Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
ORFHenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrand
5CDS-3UTRENST00000278886ENST00000310450NINLchr20

25507044

-NAA20chr20

20007428

+
5CDS-3UTRENST00000278886ENST00000310450NINLchr20

25507043

-NAA20chr20

20007427

+
5CDS-3UTRENST00000278886ENST00000398602NINLchr20

25507044

-NAA20chr20

20007428

+
5CDS-3UTRENST00000278886ENST00000398602NINLchr20

25507043

-NAA20chr20

20007427

+
5CDS-3UTRENST00000278886ENST00000484480NINLchr20

25507044

-NAA20chr20

20007428

+
5CDS-3UTRENST00000278886ENST00000484480NINLchr20

25507043

-NAA20chr20

20007427

+
5CDS-3UTRENST00000422516ENST00000310450NINLchr20

25507044

-NAA20chr20

20007428

+
5CDS-3UTRENST00000422516ENST00000310450NINLchr20

25507043

-NAA20chr20

20007427

+
5CDS-3UTRENST00000422516ENST00000398602NINLchr20

25507044

-NAA20chr20

20007428

+
5CDS-3UTRENST00000422516ENST00000398602NINLchr20

25507043

-NAA20chr20

20007427

+
5CDS-3UTRENST00000422516ENST00000484480NINLchr20

25507044

-NAA20chr20

20007428

+
5CDS-3UTRENST00000422516ENST00000484480NINLchr20

25507043

-NAA20chr20

20007427

+
In-frameENST00000278886ENST00000334982NINLchr20

25507044

-NAA20chr20

20007428

+
In-frameENST00000278886ENST00000334982NINLchr20

25507043

-NAA20chr20

20007427

+
In-frameENST00000422516ENST00000334982NINLchr20

25507044

-NAA20chr20

20007428

+
In-frameENST00000422516ENST00000334982NINLchr20

25507043

-NAA20chr20

20007427

+
intron-3CDSENST00000464285ENST00000334982NINLchr20

25507044

-NAA20chr20

20007428

+
intron-3CDSENST00000464285ENST00000334982NINLchr20

25507043

-NAA20chr20

20007427

+
intron-3UTRENST00000464285ENST00000310450NINLchr20

25507044

-NAA20chr20

20007428

+
intron-3UTRENST00000464285ENST00000310450NINLchr20

25507043

-NAA20chr20

20007427

+
intron-3UTRENST00000464285ENST00000398602NINLchr20

25507044

-NAA20chr20

20007428

+
intron-3UTRENST00000464285ENST00000398602NINLchr20

25507043

-NAA20chr20

20007427

+
intron-3UTRENST00000464285ENST00000484480NINLchr20

25507044

-NAA20chr20

20007428

+
intron-3UTRENST00000464285ENST00000484480NINLchr20

25507043

-NAA20chr20

20007427

+

check buttonORFfinder result based on the fusion transcript sequence of in-frame fusion genes.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandSeq length
(transcript)		BP loci
(transcript)		Predicted start
(transcript)		Predicted stop
(transcript)		Seq length
(amino acids)
ENST00000278886NINLchr2025507044-ENST00000334982NAA20chr2020007428+1064254256621121
ENST00000422516NINLchr2025507044-ENST00000334982NAA20chr2020007428+1064254256621121
ENST00000278886NINLchr2025507043-ENST00000334982NAA20chr2020007427+1064254256621121
ENST00000422516NINLchr2025507043-ENST00000334982NAA20chr2020007427+1064254256621121

check buttonDeepORF prediction of the coding potential based on the fusion transcript sequence of in-frame fusion genes. DeepORF is a coding potential classifier based on convolutional neural network by comparing the real Ribo-seq data. If the no-coding score < 0.5 and coding score > 0.5, then the in-frame fusion transcript is predicted as being likely translated.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandNo-coding scoreCoding score
ENST00000278886ENST00000334982NINLchr2025507044-NAA20chr2020007428+0.0083232030.9916768
ENST00000422516ENST00000334982NINLchr2025507044-NAA20chr2020007428+0.0083232030.9916768
ENST00000278886ENST00000334982NINLchr2025507043-NAA20chr2020007427+0.0083232030.9916768
ENST00000422516ENST00000334982NINLchr2025507043-NAA20chr2020007427+0.0083232030.9916768

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Fusion Genomic Features for NINL-NAA20


check buttonFusionAI prediction of the potential fusion gene breakpoint based on the pre-mature RNA sequence context (+/- 5kb of individual partner genes, total 20kb length sequence). FusionAI is a fusion gene breakpoint classifier based on convolutional neural network by comparing the fusion positive and negative sequence context of ~ 20K fusion gene data. From here, we can have the relative potentency of the 20K genomic sequence how individual sequnce will be likely used as the gene fusion breakpoints.
HgeneHchrHbpHstrandTgeneTchrTbpTstrand1-pp (fusion gene breakpoint)
NINLchr2025507043-NAA20chr2020007427+1.74E-060.9999982
NINLchr2025507043-NAA20chr2020007427+1.74E-060.9999982
NINLchr2025507043-NAA20chr2020007427+1.74E-060.9999982
NINLchr2025507043-NAA20chr2020007427+1.74E-060.9999982

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions. We integrated a total of 44 different types of human genomic feature loci information across five big categories including virus integration sites, repeats, structural variants, chromatin states, and gene expression regulation. More details are in help page.
genomic feature

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions that are ovelapped with the top 1% feature importance score regions. More details are in help page.
genomic feature of top 1%

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Fusion Protein Features for NINL-NAA20


check button Four levels of functional features of fusion genes
Go to FGviewer search page for the most frequent breakpoint (https://ccsmweb.uth.edu/FGviewer/chr20:25507044/chr20:20007428)
- FGviewer provides the online visualization of the retention search of the protein functional features across DNA, RNA, protein, and pathological levels.
- How to search
1. Put your fusion gene symbol.
2. Press the tab key until there will be shown the breakpoint information filled.
4. Go down and press 'Search' tab twice.
4. Go down to have the hyperlink of the search result.
5. Click the hyperlink.
6. See the FGviewer result for your fusion gene.
FGviewer

check buttonMain function of each fusion partner protein. (from UniProt)
HgeneTgene
NINL

Q9Y2I6

NAA20

P61599

FUNCTION: Involved in the microtubule organization in interphase cells. Overexpression induces the fragmentation of the Golgi, and causes lysosomes to disperse toward the cell periphery; it also interferes with mitotic spindle assembly. May play a role in ovarian carcinogenesis. {ECO:0000269|PubMed:12852856, ECO:0000269|PubMed:16254247, ECO:0000269|PubMed:18538832}.FUNCTION: Catalytic subunit of the NatB complex which catalyzes acetylation of the N-terminal methionine residues of peptides beginning with Met-Asp, Met-Glu, Met-Asn and Met-Gln. Proteins with cell cycle functions are overrepresented in the pool of NatB substrates. Required for maintaining the structure and function of actomyosin fibers and for proper cellular migration. {ECO:0000269|PubMed:18570629}.

check buttonRetention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at

download page


* Minus value of BPloci means that the break pointn is located before the CDS.
- In-frame and retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneNINLchr20:25507043chr20:20007427ENST00000278886-2247_42601383.0DomainEF-hand 1
HgeneNINLchr20:25507043chr20:20007427ENST00000422516-2237_42601034.0DomainEF-hand 1
HgeneNINLchr20:25507044chr20:20007428ENST00000278886-2247_42601383.0DomainEF-hand 1
HgeneNINLchr20:25507044chr20:20007428ENST00000422516-2237_42601034.0DomainEF-hand 1

- In-frame and not-retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneNINLchr20:25507043chr20:20007427ENST00000278886-224246_257601383.0Calcium bindingOntology_term=ECO:0000255
HgeneNINLchr20:25507043chr20:20007427ENST00000422516-223246_257601034.0Calcium bindingOntology_term=ECO:0000255
HgeneNINLchr20:25507044chr20:20007428ENST00000278886-224246_257601383.0Calcium bindingOntology_term=ECO:0000255
HgeneNINLchr20:25507044chr20:20007428ENST00000422516-223246_257601034.0Calcium bindingOntology_term=ECO:0000255
HgeneNINLchr20:25507043chr20:20007427ENST00000278886-2241046_1375601383.0Coiled coilOntology_term=ECO:0000255
HgeneNINLchr20:25507043chr20:20007427ENST00000278886-224384_424601383.0Coiled coilOntology_term=ECO:0000255
HgeneNINLchr20:25507043chr20:20007427ENST00000278886-224484_579601383.0Coiled coilOntology_term=ECO:0000255
HgeneNINLchr20:25507043chr20:20007427ENST00000278886-224616_699601383.0Coiled coilOntology_term=ECO:0000255
HgeneNINLchr20:25507043chr20:20007427ENST00000422516-2231046_1375601034.0Coiled coilOntology_term=ECO:0000255
HgeneNINLchr20:25507043chr20:20007427ENST00000422516-223384_424601034.0Coiled coilOntology_term=ECO:0000255
HgeneNINLchr20:25507043chr20:20007427ENST00000422516-223484_579601034.0Coiled coilOntology_term=ECO:0000255
HgeneNINLchr20:25507043chr20:20007427ENST00000422516-223616_699601034.0Coiled coilOntology_term=ECO:0000255
HgeneNINLchr20:25507044chr20:20007428ENST00000278886-2241046_1375601383.0Coiled coilOntology_term=ECO:0000255
HgeneNINLchr20:25507044chr20:20007428ENST00000278886-224384_424601383.0Coiled coilOntology_term=ECO:0000255
HgeneNINLchr20:25507044chr20:20007428ENST00000278886-224484_579601383.0Coiled coilOntology_term=ECO:0000255
HgeneNINLchr20:25507044chr20:20007428ENST00000278886-224616_699601383.0Coiled coilOntology_term=ECO:0000255
HgeneNINLchr20:25507044chr20:20007428ENST00000422516-2231046_1375601034.0Coiled coilOntology_term=ECO:0000255
HgeneNINLchr20:25507044chr20:20007428ENST00000422516-223384_424601034.0Coiled coilOntology_term=ECO:0000255
HgeneNINLchr20:25507044chr20:20007428ENST00000422516-223484_579601034.0Coiled coilOntology_term=ECO:0000255
HgeneNINLchr20:25507044chr20:20007428ENST00000422516-223616_699601034.0Coiled coilOntology_term=ECO:0000255
HgeneNINLchr20:25507043chr20:20007427ENST00000278886-224296_299601383.0Compositional biasNote=Poly-Thr
HgeneNINLchr20:25507043chr20:20007427ENST00000278886-224805_810601383.0Compositional biasNote=Poly-Glu
HgeneNINLchr20:25507043chr20:20007427ENST00000422516-223296_299601034.0Compositional biasNote=Poly-Thr
HgeneNINLchr20:25507043chr20:20007427ENST00000422516-223805_810601034.0Compositional biasNote=Poly-Glu
HgeneNINLchr20:25507044chr20:20007428ENST00000278886-224296_299601383.0Compositional biasNote=Poly-Thr
HgeneNINLchr20:25507044chr20:20007428ENST00000278886-224805_810601383.0Compositional biasNote=Poly-Glu
HgeneNINLchr20:25507044chr20:20007428ENST00000422516-223296_299601034.0Compositional biasNote=Poly-Thr
HgeneNINLchr20:25507044chr20:20007428ENST00000422516-223805_810601034.0Compositional biasNote=Poly-Glu
HgeneNINLchr20:25507043chr20:20007427ENST00000278886-224196_231601383.0DomainEF-hand 3
HgeneNINLchr20:25507043chr20:20007427ENST00000278886-224233_268601383.0DomainEF-hand 4
HgeneNINLchr20:25507043chr20:20007427ENST00000278886-22441_76601383.0DomainEF-hand 2
HgeneNINLchr20:25507043chr20:20007427ENST00000422516-223196_231601034.0DomainEF-hand 3
HgeneNINLchr20:25507043chr20:20007427ENST00000422516-223233_268601034.0DomainEF-hand 4
HgeneNINLchr20:25507043chr20:20007427ENST00000422516-22341_76601034.0DomainEF-hand 2
HgeneNINLchr20:25507044chr20:20007428ENST00000278886-224196_231601383.0DomainEF-hand 3
HgeneNINLchr20:25507044chr20:20007428ENST00000278886-224233_268601383.0DomainEF-hand 4
HgeneNINLchr20:25507044chr20:20007428ENST00000278886-22441_76601383.0DomainEF-hand 2
HgeneNINLchr20:25507044chr20:20007428ENST00000422516-223196_231601034.0DomainEF-hand 3
HgeneNINLchr20:25507044chr20:20007428ENST00000422516-223233_268601034.0DomainEF-hand 4
HgeneNINLchr20:25507044chr20:20007428ENST00000422516-22341_76601034.0DomainEF-hand 2
HgeneNINLchr20:25507043chr20:20007427ENST00000278886-224633_641601383.0MotifNote=D-box
HgeneNINLchr20:25507043chr20:20007427ENST00000422516-223633_641601034.0MotifNote=D-box
HgeneNINLchr20:25507044chr20:20007428ENST00000278886-224633_641601383.0MotifNote=D-box
HgeneNINLchr20:25507044chr20:20007428ENST00000422516-223633_641601034.0MotifNote=D-box
TgeneNAA20chr20:25507043chr20:20007427ENST00000310450252_15756112.0DomainN-acetyltransferase
TgeneNAA20chr20:25507043chr20:20007427ENST00000334982262_15756179.0DomainN-acetyltransferase
TgeneNAA20chr20:25507044chr20:20007428ENST00000310450252_15756112.0DomainN-acetyltransferase
TgeneNAA20chr20:25507044chr20:20007428ENST00000334982262_15756179.0DomainN-acetyltransferase


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Fusion Gene Sequence for NINL-NAA20


check button For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. To have fusion amino acid sequence, we ran ORFfinder and chose the longest ORF among the all predicted ones.
>59154_59154_1_NINL-NAA20_NINL_chr20_25507043_ENST00000278886_NAA20_chr20_20007427_ENST00000334982_length(transcript)=1064nt_BP=254nt
GCGGTACGGGGGTGGTGCCGCGCTCCTGGCCCCGCGCGGGCGGACGGCGGAGGCGCCTCCCAGCCTGCTATGGGATGGATGAAGAAGAGA
ACCACTATGTCTCGCAGCTCAGGGAAGTCTACAGCAGCTGCGACACCACGGGGACTGGCTTTCTGGACCGCCAGGAGCTGACCCAGCTCT
GCCTTAAGCTTCACCTGGAGCAGCAGCTGCCCGTCCTCCTGCAGACGCTTCTCGGAAACGACCATTTCGCCAGGTTATGGGTAAAGCAGA
AGGCTCAGTAGCTAGGGAAGAATGGCACGGGCACGTCACAGCTCTGTCTGTTGCCCCAGAATTTCGACGCCTTGGTTTGGCTGCTAAACT
TATGGAGTTACTAGAGGAGATTTCAGAAAGAAAGGGTGGATTTTTTGTGGATCTCTTTGTAAGAGTATCTAACCAAGTTGCAGTTAACAT
GTACAAGCAGTTGGGCTACAGTGTATATAGGACGGTCATAGAGTACTATTCGGCCAGCAACGGGGAGCCTGATGAGGACGCTTATGATAT
GAGGAAAGCACTTTCCAGGGATACTGAGAAGAAATCCATCATACCATTACCTCATCCTGTGAGGCCTGAAGACATTGAATAACCCTGGGC
AGTGGTTCTTAGGCAGATACTCTAGATGCTTTATGGACAATATTATTTTCATTGGATGATTCTGGAGCTCTATTAGGAGAAAAGTAATCA
TTTTAGGTCTTAAAGACTTCAAGAAAATACAGGTTATCAATTTATTTTAAATCTCATTGTTTCCAGTTAGCAATATCATACCTATTAAAG
CTGTTCATTGTAACAAAATTCAATCAAAAAGGCAGCTAGGTCAGAAGGAAACATACCACTCTCATGGTTCATAGTATTCACTGTATGTAT
GCTAGGGAAAAGACTTGCTCCAGTCTCCTCCTCAGTTCTGTGCCTGAGAACCACTGCTGCATATATTTGTTTTTAAATTTTGTATTGAAC

>59154_59154_1_NINL-NAA20_NINL_chr20_25507043_ENST00000278886_NAA20_chr20_20007427_ENST00000334982_length(amino acids)=121AA_BP=0
MGKAEGSVAREEWHGHVTALSVAPEFRRLGLAAKLMELLEEISERKGGFFVDLFVRVSNQVAVNMYKQLGYSVYRTVIEYYSASNGEPDE

--------------------------------------------------------------
>59154_59154_2_NINL-NAA20_NINL_chr20_25507043_ENST00000422516_NAA20_chr20_20007427_ENST00000334982_length(transcript)=1064nt_BP=254nt
GCGGTACGGGGGTGGTGCCGCGCTCCTGGCCCCGCGCGGGCGGACGGCGGAGGCGCCTCCCAGCCTGCTATGGGATGGATGAAGAAGAGA
ACCACTATGTCTCGCAGCTCAGGGAAGTCTACAGCAGCTGCGACACCACGGGGACTGGCTTTCTGGACCGCCAGGAGCTGACCCAGCTCT
GCCTTAAGCTTCACCTGGAGCAGCAGCTGCCCGTCCTCCTGCAGACGCTTCTCGGAAACGACCATTTCGCCAGGTTATGGGTAAAGCAGA
AGGCTCAGTAGCTAGGGAAGAATGGCACGGGCACGTCACAGCTCTGTCTGTTGCCCCAGAATTTCGACGCCTTGGTTTGGCTGCTAAACT
TATGGAGTTACTAGAGGAGATTTCAGAAAGAAAGGGTGGATTTTTTGTGGATCTCTTTGTAAGAGTATCTAACCAAGTTGCAGTTAACAT
GTACAAGCAGTTGGGCTACAGTGTATATAGGACGGTCATAGAGTACTATTCGGCCAGCAACGGGGAGCCTGATGAGGACGCTTATGATAT
GAGGAAAGCACTTTCCAGGGATACTGAGAAGAAATCCATCATACCATTACCTCATCCTGTGAGGCCTGAAGACATTGAATAACCCTGGGC
AGTGGTTCTTAGGCAGATACTCTAGATGCTTTATGGACAATATTATTTTCATTGGATGATTCTGGAGCTCTATTAGGAGAAAAGTAATCA
TTTTAGGTCTTAAAGACTTCAAGAAAATACAGGTTATCAATTTATTTTAAATCTCATTGTTTCCAGTTAGCAATATCATACCTATTAAAG
CTGTTCATTGTAACAAAATTCAATCAAAAAGGCAGCTAGGTCAGAAGGAAACATACCACTCTCATGGTTCATAGTATTCACTGTATGTAT
GCTAGGGAAAAGACTTGCTCCAGTCTCCTCCTCAGTTCTGTGCCTGAGAACCACTGCTGCATATATTTGTTTTTAAATTTTGTATTGAAC

>59154_59154_2_NINL-NAA20_NINL_chr20_25507043_ENST00000422516_NAA20_chr20_20007427_ENST00000334982_length(amino acids)=121AA_BP=0
MGKAEGSVAREEWHGHVTALSVAPEFRRLGLAAKLMELLEEISERKGGFFVDLFVRVSNQVAVNMYKQLGYSVYRTVIEYYSASNGEPDE

--------------------------------------------------------------
>59154_59154_3_NINL-NAA20_NINL_chr20_25507044_ENST00000278886_NAA20_chr20_20007428_ENST00000334982_length(transcript)=1064nt_BP=254nt
GCGGTACGGGGGTGGTGCCGCGCTCCTGGCCCCGCGCGGGCGGACGGCGGAGGCGCCTCCCAGCCTGCTATGGGATGGATGAAGAAGAGA
ACCACTATGTCTCGCAGCTCAGGGAAGTCTACAGCAGCTGCGACACCACGGGGACTGGCTTTCTGGACCGCCAGGAGCTGACCCAGCTCT
GCCTTAAGCTTCACCTGGAGCAGCAGCTGCCCGTCCTCCTGCAGACGCTTCTCGGAAACGACCATTTCGCCAGGTTATGGGTAAAGCAGA
AGGCTCAGTAGCTAGGGAAGAATGGCACGGGCACGTCACAGCTCTGTCTGTTGCCCCAGAATTTCGACGCCTTGGTTTGGCTGCTAAACT
TATGGAGTTACTAGAGGAGATTTCAGAAAGAAAGGGTGGATTTTTTGTGGATCTCTTTGTAAGAGTATCTAACCAAGTTGCAGTTAACAT
GTACAAGCAGTTGGGCTACAGTGTATATAGGACGGTCATAGAGTACTATTCGGCCAGCAACGGGGAGCCTGATGAGGACGCTTATGATAT
GAGGAAAGCACTTTCCAGGGATACTGAGAAGAAATCCATCATACCATTACCTCATCCTGTGAGGCCTGAAGACATTGAATAACCCTGGGC
AGTGGTTCTTAGGCAGATACTCTAGATGCTTTATGGACAATATTATTTTCATTGGATGATTCTGGAGCTCTATTAGGAGAAAAGTAATCA
TTTTAGGTCTTAAAGACTTCAAGAAAATACAGGTTATCAATTTATTTTAAATCTCATTGTTTCCAGTTAGCAATATCATACCTATTAAAG
CTGTTCATTGTAACAAAATTCAATCAAAAAGGCAGCTAGGTCAGAAGGAAACATACCACTCTCATGGTTCATAGTATTCACTGTATGTAT
GCTAGGGAAAAGACTTGCTCCAGTCTCCTCCTCAGTTCTGTGCCTGAGAACCACTGCTGCATATATTTGTTTTTAAATTTTGTATTGAAC

>59154_59154_3_NINL-NAA20_NINL_chr20_25507044_ENST00000278886_NAA20_chr20_20007428_ENST00000334982_length(amino acids)=121AA_BP=0
MGKAEGSVAREEWHGHVTALSVAPEFRRLGLAAKLMELLEEISERKGGFFVDLFVRVSNQVAVNMYKQLGYSVYRTVIEYYSASNGEPDE

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>59154_59154_4_NINL-NAA20_NINL_chr20_25507044_ENST00000422516_NAA20_chr20_20007428_ENST00000334982_length(transcript)=1064nt_BP=254nt
GCGGTACGGGGGTGGTGCCGCGCTCCTGGCCCCGCGCGGGCGGACGGCGGAGGCGCCTCCCAGCCTGCTATGGGATGGATGAAGAAGAGA
ACCACTATGTCTCGCAGCTCAGGGAAGTCTACAGCAGCTGCGACACCACGGGGACTGGCTTTCTGGACCGCCAGGAGCTGACCCAGCTCT
GCCTTAAGCTTCACCTGGAGCAGCAGCTGCCCGTCCTCCTGCAGACGCTTCTCGGAAACGACCATTTCGCCAGGTTATGGGTAAAGCAGA
AGGCTCAGTAGCTAGGGAAGAATGGCACGGGCACGTCACAGCTCTGTCTGTTGCCCCAGAATTTCGACGCCTTGGTTTGGCTGCTAAACT
TATGGAGTTACTAGAGGAGATTTCAGAAAGAAAGGGTGGATTTTTTGTGGATCTCTTTGTAAGAGTATCTAACCAAGTTGCAGTTAACAT
GTACAAGCAGTTGGGCTACAGTGTATATAGGACGGTCATAGAGTACTATTCGGCCAGCAACGGGGAGCCTGATGAGGACGCTTATGATAT
GAGGAAAGCACTTTCCAGGGATACTGAGAAGAAATCCATCATACCATTACCTCATCCTGTGAGGCCTGAAGACATTGAATAACCCTGGGC
AGTGGTTCTTAGGCAGATACTCTAGATGCTTTATGGACAATATTATTTTCATTGGATGATTCTGGAGCTCTATTAGGAGAAAAGTAATCA
TTTTAGGTCTTAAAGACTTCAAGAAAATACAGGTTATCAATTTATTTTAAATCTCATTGTTTCCAGTTAGCAATATCATACCTATTAAAG
CTGTTCATTGTAACAAAATTCAATCAAAAAGGCAGCTAGGTCAGAAGGAAACATACCACTCTCATGGTTCATAGTATTCACTGTATGTAT
GCTAGGGAAAAGACTTGCTCCAGTCTCCTCCTCAGTTCTGTGCCTGAGAACCACTGCTGCATATATTTGTTTTTAAATTTTGTATTGAAC

>59154_59154_4_NINL-NAA20_NINL_chr20_25507044_ENST00000422516_NAA20_chr20_20007428_ENST00000334982_length(amino acids)=121AA_BP=0
MGKAEGSVAREEWHGHVTALSVAPEFRRLGLAAKLMELLEEISERKGGFFVDLFVRVSNQVAVNMYKQLGYSVYRTVIEYYSASNGEPDE

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Fusion Gene PPI Analysis for NINL-NAA20


check button Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in

ChiPPI page.


check button Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160)
HgeneHgene's interactorsTgeneTgene's interactors


check button - Retained PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenStill interaction with


check button - Lost PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


check button - Retained PPIs, but lost function due to frame-shift fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


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Related Drugs for NINL-NAA20


check button Drugs targeting genes involved in this fusion gene.
(DrugBank Version 5.1.8 2021-05-08)
PartnerGeneUniProtAccDrugBank IDDrug nameDrug activityDrug typeDrug status

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Related Diseases for NINL-NAA20


check button Diseases associated with fusion partners.
(DisGeNet 4.0)
PartnerGeneDisease IDDisease name# pubmedsSource