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Center for Computational Systems Medicine
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Fusion Gene Summary

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Fusion Gene ORF analysis

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Fusion Genomic Features

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Fusion Protein Features

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Fusion Gene Sequence

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Fusion Gene PPI analysis

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Related Drugs

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Fusion gene:NIN-NEMF (FusionGDB2 ID:59159)

Fusion Gene Summary for NIN-NEMF

check button Fusion gene summary
Fusion gene informationFusion gene name: NIN-NEMF
Fusion gene ID: 59159
HgeneTgene
Gene symbol

NIN

NEMF

Gene ID

51199

9147

Gene namenineinnuclear export mediator factor
SynonymsSCKL7NY-CO-1|SDCCAG1
Cytomap

14q22.1

14q21.3

Type of geneprotein-codingprotein-coding
Descriptionnineinglycogen synthase kinase 3 beta-interacting proteinhNineinninein (GSK3B interacting protein)ninein centrosomal proteinnuclear export mediator factor NEMFantigen NY-CO-1serologically defined colon cancer antigen 1
Modification date2020032820200313
UniProtAcc

Q8N4C6

O60524

Ensembl transtripts involved in fusion geneENST00000245441, ENST00000324330, 
ENST00000382041, ENST00000382043, 
ENST00000389868, ENST00000453196, 
ENST00000530997, ENST00000486200, 
ENST00000546046, ENST00000556925, 
ENST00000382135, ENST00000545773, 
ENST00000556672, ENST00000298310, 
Fusion gene scores* DoF score16 X 18 X 9=25926 X 8 X 4=192
# samples 209
** MAII scorelog2(20/2592*10)=-3.6959938131099
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0
log2(9/192*10)=-1.09310940439148
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0
Context

PubMed: NIN [Title/Abstract] AND NEMF [Title/Abstract] AND fusion [Title/Abstract]

Most frequent breakpointNIN(51273455)-NEMF(50292673), # samples:2
Anticipated loss of major functional domain due to fusion event.NIN-NEMF seems lost the major protein functional domain in Hgene partner, which is a CGC due to the frame-shifted ORF.
NIN-NEMF seems lost the major protein functional domain in Hgene partner, which is a essential gene due to the frame-shifted ORF.
NIN-NEMF seems lost the major protein functional domain in Tgene partner, which is a essential gene due to the frame-shifted ORF.
* DoF score (Degree of Frequency) = # partners X # break points X # cancer types
** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)

check button Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez
PartnerGeneGO IDGO termPubMed ID

check buttonFusion gene breakpoints across NIN (5'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check buttonFusion gene breakpoints across NEMF (3'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check button Fusion gene information from two resources (ChiTars 5.0 and ChimerDB 4.0)
* All genome coordinats were lifted-over on hg19.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
SourceDiseaseSampleHgeneHchrHbpHstrandTgeneTchrTbpTstrand
ChimerDB4BRCATCGA-BH-A1FE-01ANINchr14

51273455

-NEMFchr14

50292673

-


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Fusion Gene ORF analysis for NIN-NEMF

check button Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
ORFHenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrand
5CDS-5UTRENST00000245441ENST00000546046NINchr14

51273455

-NEMFchr14

50292673

-
5CDS-5UTRENST00000245441ENST00000556925NINchr14

51273455

-NEMFchr14

50292673

-
5CDS-5UTRENST00000324330ENST00000546046NINchr14

51273455

-NEMFchr14

50292673

-
5CDS-5UTRENST00000324330ENST00000556925NINchr14

51273455

-NEMFchr14

50292673

-
5CDS-5UTRENST00000382041ENST00000546046NINchr14

51273455

-NEMFchr14

50292673

-
5CDS-5UTRENST00000382041ENST00000556925NINchr14

51273455

-NEMFchr14

50292673

-
5CDS-5UTRENST00000382043ENST00000546046NINchr14

51273455

-NEMFchr14

50292673

-
5CDS-5UTRENST00000382043ENST00000556925NINchr14

51273455

-NEMFchr14

50292673

-
5CDS-5UTRENST00000389868ENST00000546046NINchr14

51273455

-NEMFchr14

50292673

-
5CDS-5UTRENST00000389868ENST00000556925NINchr14

51273455

-NEMFchr14

50292673

-
5CDS-5UTRENST00000453196ENST00000546046NINchr14

51273455

-NEMFchr14

50292673

-
5CDS-5UTRENST00000453196ENST00000556925NINchr14

51273455

-NEMFchr14

50292673

-
5CDS-5UTRENST00000530997ENST00000546046NINchr14

51273455

-NEMFchr14

50292673

-
5CDS-5UTRENST00000530997ENST00000556925NINchr14

51273455

-NEMFchr14

50292673

-
5CDS-intronENST00000245441ENST00000382135NINchr14

51273455

-NEMFchr14

50292673

-
5CDS-intronENST00000245441ENST00000545773NINchr14

51273455

-NEMFchr14

50292673

-
5CDS-intronENST00000245441ENST00000556672NINchr14

51273455

-NEMFchr14

50292673

-
5CDS-intronENST00000324330ENST00000382135NINchr14

51273455

-NEMFchr14

50292673

-
5CDS-intronENST00000324330ENST00000545773NINchr14

51273455

-NEMFchr14

50292673

-
5CDS-intronENST00000324330ENST00000556672NINchr14

51273455

-NEMFchr14

50292673

-
5CDS-intronENST00000382041ENST00000382135NINchr14

51273455

-NEMFchr14

50292673

-
5CDS-intronENST00000382041ENST00000545773NINchr14

51273455

-NEMFchr14

50292673

-
5CDS-intronENST00000382041ENST00000556672NINchr14

51273455

-NEMFchr14

50292673

-
5CDS-intronENST00000382043ENST00000382135NINchr14

51273455

-NEMFchr14

50292673

-
5CDS-intronENST00000382043ENST00000545773NINchr14

51273455

-NEMFchr14

50292673

-
5CDS-intronENST00000382043ENST00000556672NINchr14

51273455

-NEMFchr14

50292673

-
5CDS-intronENST00000389868ENST00000382135NINchr14

51273455

-NEMFchr14

50292673

-
5CDS-intronENST00000389868ENST00000545773NINchr14

51273455

-NEMFchr14

50292673

-
5CDS-intronENST00000389868ENST00000556672NINchr14

51273455

-NEMFchr14

50292673

-
5CDS-intronENST00000453196ENST00000382135NINchr14

51273455

-NEMFchr14

50292673

-
5CDS-intronENST00000453196ENST00000545773NINchr14

51273455

-NEMFchr14

50292673

-
5CDS-intronENST00000453196ENST00000556672NINchr14

51273455

-NEMFchr14

50292673

-
5CDS-intronENST00000530997ENST00000382135NINchr14

51273455

-NEMFchr14

50292673

-
5CDS-intronENST00000530997ENST00000545773NINchr14

51273455

-NEMFchr14

50292673

-
5CDS-intronENST00000530997ENST00000556672NINchr14

51273455

-NEMFchr14

50292673

-
Frame-shiftENST00000245441ENST00000298310NINchr14

51273455

-NEMFchr14

50292673

-
Frame-shiftENST00000382041ENST00000298310NINchr14

51273455

-NEMFchr14

50292673

-
Frame-shiftENST00000453196ENST00000298310NINchr14

51273455

-NEMFchr14

50292673

-
Frame-shiftENST00000530997ENST00000298310NINchr14

51273455

-NEMFchr14

50292673

-
In-frameENST00000324330ENST00000298310NINchr14

51273455

-NEMFchr14

50292673

-
In-frameENST00000382043ENST00000298310NINchr14

51273455

-NEMFchr14

50292673

-
In-frameENST00000389868ENST00000298310NINchr14

51273455

-NEMFchr14

50292673

-
intron-3CDSENST00000486200ENST00000298310NINchr14

51273455

-NEMFchr14

50292673

-
intron-5UTRENST00000486200ENST00000546046NINchr14

51273455

-NEMFchr14

50292673

-
intron-5UTRENST00000486200ENST00000556925NINchr14

51273455

-NEMFchr14

50292673

-
intron-intronENST00000486200ENST00000382135NINchr14

51273455

-NEMFchr14

50292673

-
intron-intronENST00000486200ENST00000545773NINchr14

51273455

-NEMFchr14

50292673

-
intron-intronENST00000486200ENST00000556672NINchr14

51273455

-NEMFchr14

50292673

-

check buttonORFfinder result based on the fusion transcript sequence of in-frame fusion genes.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandSeq length
(transcript)
BP loci
(transcript)
Predicted start
(transcript)
Predicted stop
(transcript)
Seq length
(amino acids)
ENST00000389868NINchr1451273455-ENST00000298310NEMFchr1450292673-35564564322198588
ENST00000382043NINchr1451273455-ENST00000298310NEMFchr1450292673-34023022782044588
ENST00000324330NINchr1451273455-ENST00000298310NEMFchr1450292673-35564564322198588

check buttonDeepORF prediction of the coding potential based on the fusion transcript sequence of in-frame fusion genes. DeepORF is a coding potential classifier based on convolutional neural network by comparing the real Ribo-seq data. If the no-coding score < 0.5 and coding score > 0.5, then the in-frame fusion transcript is predicted as being likely translated.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandNo-coding scoreCoding score
ENST00000389868ENST00000298310NINchr1451273455-NEMFchr1450292673-0.0003108780.9996891
ENST00000382043ENST00000298310NINchr1451273455-NEMFchr1450292673-0.0003458370.9996542
ENST00000324330ENST00000298310NINchr1451273455-NEMFchr1450292673-0.0003108780.9996891

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Fusion Genomic Features for NIN-NEMF


check buttonFusionAI prediction of the potential fusion gene breakpoint based on the pre-mature RNA sequence context (+/- 5kb of individual partner genes, total 20kb length sequence). FusionAI is a fusion gene breakpoint classifier based on convolutional neural network by comparing the fusion positive and negative sequence context of ~ 20K fusion gene data. From here, we can have the relative potentency of the 20K genomic sequence how individual sequnce will be likely used as the gene fusion breakpoints.
HgeneHchrHbpHstrandTgeneTchrTbpTstrand1-pp (fusion gene breakpoint)

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions. We integrated a total of 44 different types of human genomic feature loci information across five big categories including virus integration sites, repeats, structural variants, chromatin states, and gene expression regulation. More details are in help page.
genomic feature

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions that are ovelapped with the top 1% feature importance score regions. More details are in help page.

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Fusion Protein Features for NIN-NEMF


check button Four levels of functional features of fusion genes
Go to FGviewer search page for the most frequent breakpoint (https://ccsmweb.uth.edu/FGviewer/chr14:51273455/chr14:50292673)
- FGviewer provides the online visualization of the retention search of the protein functional features across DNA, RNA, protein, and pathological levels.
- How to search
1. Put your fusion gene symbol.
2. Press the tab key until there will be shown the breakpoint information filled.
4. Go down and press 'Search' tab twice.
4. Go down to have the hyperlink of the search result.
5. Click the hyperlink.
6. See the FGviewer result for your fusion gene.
FGviewer

check buttonMain function of each fusion partner protein. (from UniProt)
HgeneTgene
NIN

Q8N4C6

NEMF

O60524

FUNCTION: Centrosomal protein required in the positioning and anchorage of the microtubule minus-end in epithelial cells (PubMed:15190203, PubMed:23386061). May also act as a centrosome maturation factor (PubMed:11956314). May play a role in microtubule nucleation, by recruiting the gamma-tubulin ring complex to the centrosome (PubMed:15190203). Overexpression does not perturb nucleation or elongation of microtubules but suppresses release of microtubules (PubMed:15190203). Required for centriole organization and microtubule anchoring at the mother centriole (PubMed:23386061). {ECO:0000269|PubMed:11956314, ECO:0000269|PubMed:15190203, ECO:0000269|PubMed:23386061}.FUNCTION: Component of the ribosome quality control complex (RQC), a ribosome-associated complex that mediates ubiquitination and extraction of incompletely synthesized nascent chains for proteasomal degradation. NEMF is responsible for selective recognition of stalled 60S subunits by recognizing an exposed, nascent chain-conjugated tRNA moiety. NEMF is important for the stable association of LTN1 to the complex (PubMed:25578875). May indirectly play a role in nuclear export (PubMed:16103875). {ECO:0000269|PubMed:16103875, ECO:0000269|PubMed:25578875}.

check buttonRetention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at

download page


* Minus value of BPloci means that the break pointn is located before the CDS.
- In-frame and retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneNINchr14:51273455chr14:50292673ENST00000245441-43142_77882134.0DomainEF-hand 2
HgeneNINchr14:51273455chr14:50292673ENST00000245441-4318_43882134.0DomainEF-hand 1
HgeneNINchr14:51273455chr14:50292673ENST00000382041-43042_77882091.0DomainEF-hand 2
HgeneNINchr14:51273455chr14:50292673ENST00000382041-4308_43882091.0DomainEF-hand 1
HgeneNINchr14:51273455chr14:50292673ENST00000382043-32842_77881378.0DomainEF-hand 2
HgeneNINchr14:51273455chr14:50292673ENST00000382043-3288_43881378.0DomainEF-hand 1
HgeneNINchr14:51273455chr14:50292673ENST00000530997-22942_77882134.0DomainEF-hand 2
HgeneNINchr14:51273455chr14:50292673ENST00000530997-2298_43882134.0DomainEF-hand 1
TgeneNEMFchr14:51273455chr14:50292673ENST000002983101433869_8944961077.0Coiled coilOntology_term=ECO:0000255
TgeneNEMFchr14:51273455chr14:50292673ENST0000038213509296_3590277.0Coiled coilOntology_term=ECO:0000255
TgeneNEMFchr14:51273455chr14:50292673ENST0000038213509483_5140277.0Coiled coilOntology_term=ECO:0000255
TgeneNEMFchr14:51273455chr14:50292673ENST0000038213509869_8940277.0Coiled coilOntology_term=ECO:0000255
TgeneNEMFchr14:51273455chr14:50292673ENST000005457731332483_5144541035.0Coiled coilOntology_term=ECO:0000255
TgeneNEMFchr14:51273455chr14:50292673ENST000005457731332869_8944541035.0Coiled coilOntology_term=ECO:0000255
TgeneNEMFchr14:51273455chr14:50292673ENST000005460461432869_8944961056.0Coiled coilOntology_term=ECO:0000255

- In-frame and not-retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneNINchr14:51273455chr14:50292673ENST00000245441-4311068_1099882134.0Coiled coilOntology_term=ECO:0000255
HgeneNINchr14:51273455chr14:50292673ENST00000245441-4311181_1341882134.0Coiled coilOntology_term=ECO:0000255
HgeneNINchr14:51273455chr14:50292673ENST00000245441-4311441_1816882134.0Coiled coilOntology_term=ECO:0000255
HgeneNINchr14:51273455chr14:50292673ENST00000245441-4311854_1885882134.0Coiled coilOntology_term=ECO:0000255
HgeneNINchr14:51273455chr14:50292673ENST00000245441-4311922_2067882134.0Coiled coilOntology_term=ECO:0000255
HgeneNINchr14:51273455chr14:50292673ENST00000245441-431357_570882134.0Coiled coilOntology_term=ECO:0000255
HgeneNINchr14:51273455chr14:50292673ENST00000245441-431625_1027882134.0Coiled coilOntology_term=ECO:0000255
HgeneNINchr14:51273455chr14:50292673ENST00000382041-4301068_1099882091.0Coiled coilOntology_term=ECO:0000255
HgeneNINchr14:51273455chr14:50292673ENST00000382041-4301181_1341882091.0Coiled coilOntology_term=ECO:0000255
HgeneNINchr14:51273455chr14:50292673ENST00000382041-4301441_1816882091.0Coiled coilOntology_term=ECO:0000255
HgeneNINchr14:51273455chr14:50292673ENST00000382041-4301854_1885882091.0Coiled coilOntology_term=ECO:0000255
HgeneNINchr14:51273455chr14:50292673ENST00000382041-4301922_2067882091.0Coiled coilOntology_term=ECO:0000255
HgeneNINchr14:51273455chr14:50292673ENST00000382041-430357_570882091.0Coiled coilOntology_term=ECO:0000255
HgeneNINchr14:51273455chr14:50292673ENST00000382041-430625_1027882091.0Coiled coilOntology_term=ECO:0000255
HgeneNINchr14:51273455chr14:50292673ENST00000382043-3281068_1099881378.0Coiled coilOntology_term=ECO:0000255
HgeneNINchr14:51273455chr14:50292673ENST00000382043-3281181_1341881378.0Coiled coilOntology_term=ECO:0000255
HgeneNINchr14:51273455chr14:50292673ENST00000382043-3281441_1816881378.0Coiled coilOntology_term=ECO:0000255
HgeneNINchr14:51273455chr14:50292673ENST00000382043-3281854_1885881378.0Coiled coilOntology_term=ECO:0000255
HgeneNINchr14:51273455chr14:50292673ENST00000382043-3281922_2067881378.0Coiled coilOntology_term=ECO:0000255
HgeneNINchr14:51273455chr14:50292673ENST00000382043-328357_570881378.0Coiled coilOntology_term=ECO:0000255
HgeneNINchr14:51273455chr14:50292673ENST00000382043-328625_1027881378.0Coiled coilOntology_term=ECO:0000255
HgeneNINchr14:51273455chr14:50292673ENST00000530997-2291068_1099882134.0Coiled coilOntology_term=ECO:0000255
HgeneNINchr14:51273455chr14:50292673ENST00000530997-2291181_1341882134.0Coiled coilOntology_term=ECO:0000255
HgeneNINchr14:51273455chr14:50292673ENST00000530997-2291441_1816882134.0Coiled coilOntology_term=ECO:0000255
HgeneNINchr14:51273455chr14:50292673ENST00000530997-2291854_1885882134.0Coiled coilOntology_term=ECO:0000255
HgeneNINchr14:51273455chr14:50292673ENST00000530997-2291922_2067882134.0Coiled coilOntology_term=ECO:0000255
HgeneNINchr14:51273455chr14:50292673ENST00000530997-229357_570882134.0Coiled coilOntology_term=ECO:0000255
HgeneNINchr14:51273455chr14:50292673ENST00000530997-229625_1027882134.0Coiled coilOntology_term=ECO:0000255
HgeneNINchr14:51273455chr14:50292673ENST00000245441-431182_217882134.0DomainEF-hand 3
HgeneNINchr14:51273455chr14:50292673ENST00000245441-431219_252882134.0DomainEF-hand 4
HgeneNINchr14:51273455chr14:50292673ENST00000245441-431317_352882134.0DomainEF-hand 5
HgeneNINchr14:51273455chr14:50292673ENST00000382041-430182_217882091.0DomainEF-hand 3
HgeneNINchr14:51273455chr14:50292673ENST00000382041-430219_252882091.0DomainEF-hand 4
HgeneNINchr14:51273455chr14:50292673ENST00000382041-430317_352882091.0DomainEF-hand 5
HgeneNINchr14:51273455chr14:50292673ENST00000382043-328182_217881378.0DomainEF-hand 3
HgeneNINchr14:51273455chr14:50292673ENST00000382043-328219_252881378.0DomainEF-hand 4
HgeneNINchr14:51273455chr14:50292673ENST00000382043-328317_352881378.0DomainEF-hand 5
HgeneNINchr14:51273455chr14:50292673ENST00000530997-229182_217882134.0DomainEF-hand 3
HgeneNINchr14:51273455chr14:50292673ENST00000530997-229219_252882134.0DomainEF-hand 4
HgeneNINchr14:51273455chr14:50292673ENST00000530997-229317_352882134.0DomainEF-hand 5
HgeneNINchr14:51273455chr14:50292673ENST00000245441-431245_252882134.0Nucleotide bindingGTP
HgeneNINchr14:51273455chr14:50292673ENST00000245441-431300_304882134.0Nucleotide bindingGTP
HgeneNINchr14:51273455chr14:50292673ENST00000245441-431420_423882134.0Nucleotide bindingGTP
HgeneNINchr14:51273455chr14:50292673ENST00000382041-430245_252882091.0Nucleotide bindingGTP
HgeneNINchr14:51273455chr14:50292673ENST00000382041-430300_304882091.0Nucleotide bindingGTP
HgeneNINchr14:51273455chr14:50292673ENST00000382041-430420_423882091.0Nucleotide bindingGTP
HgeneNINchr14:51273455chr14:50292673ENST00000382043-328245_252881378.0Nucleotide bindingGTP
HgeneNINchr14:51273455chr14:50292673ENST00000382043-328300_304881378.0Nucleotide bindingGTP
HgeneNINchr14:51273455chr14:50292673ENST00000382043-328420_423881378.0Nucleotide bindingGTP
HgeneNINchr14:51273455chr14:50292673ENST00000530997-229245_252882134.0Nucleotide bindingGTP
HgeneNINchr14:51273455chr14:50292673ENST00000530997-229300_304882134.0Nucleotide bindingGTP
HgeneNINchr14:51273455chr14:50292673ENST00000530997-229420_423882134.0Nucleotide bindingGTP
TgeneNEMFchr14:51273455chr14:50292673ENST000002983101433296_3594961077.0Coiled coilOntology_term=ECO:0000255
TgeneNEMFchr14:51273455chr14:50292673ENST000002983101433483_5144961077.0Coiled coilOntology_term=ECO:0000255
TgeneNEMFchr14:51273455chr14:50292673ENST000005457731332296_3594541035.0Coiled coilOntology_term=ECO:0000255
TgeneNEMFchr14:51273455chr14:50292673ENST000005460461432296_3594961056.0Coiled coilOntology_term=ECO:0000255
TgeneNEMFchr14:51273455chr14:50292673ENST000005460461432483_5144961056.0Coiled coilOntology_term=ECO:0000255


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Fusion Gene Sequence for NIN-NEMF


check button For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. To have fusion amino acid sequence, we ran ORFfinder and chose the longest ORF among the all predicted ones.
>59159_59159_1_NIN-NEMF_NIN_chr14_51273455_ENST00000324330_NEMF_chr14_50292673_ENST00000298310_length(transcript)=3556nt_BP=456nt
CCGAGCCGGGAGCCGAGCGCGCTGGGCGCGGCCGTCCCGCTGCCGCCGCCAAGCCCGGAGTGCGCCAGCGGCCATGGTTCCCGCGGCGGC
GCCGGGCGCCTGAGCCCCGGGACGCAAGCGCTGGAGGCGGGCTGCCGGCTGTGCGGGCGCTCCGGAGAGACCGACAGAAGGTGAGCACTG
TGGGCTATGGGATGGATGAGGTGGAGCAGGACCAGCATGAGGCCCGACTCAAGGAGCTGTTTGACAGTTTTGACACGACGGGCACAGGGT
CCCTGGGGCAGGAGGAACTCACCGACCTTTGCCACATGTTGAGCTTGGAGGAGGTGGCCCCAGTGCTGCAGCAGACATTACTTCAGGACA
ACCTCTTGGGCAGGGTACATTTTGACCAATTTAAAGAAGCATTAATACTCATCTTGTCCAGAACTCTGTCAAATGAAGAACACTTTCAAG
AACCAGGCATTCAAGTCAGCAGAAAAGAAAACAAAGCAAACATTAAAAGAAGTTCAGACTGTTACCTCTATTCAAAAAGCAAGAAAAGTA
TATTGGTTTGAGAAATTTCTGTGGTTCATTAGCTCAGAGAACTATCTAATTATAGGTGGACGAGATCAGCAACAGAATGAAATAATTGTG
AAAAGATACTTGACACCAGGAGACATTTATGTACATGCTGATCTTCATGGAGCTACTAGCTGTGTAATTAAGAATCCAACAGGAGAACCC
ATCCCCCCACGGACCTTGACTGAAGCTGGCACAATGGCACTTTGCTACAGTGCTGCTTGGGATGCACGAGTTATCACTAGTGCTTGGTGG
GTGTACCATCATCAGGTATCTAAAACAGCACCAACTGGAGAATATTTGACAACAGGAAGCTTCATGATAAGAGGAAAAAAGAATTTTCTT
CCTCCCTCATATCTAATGATGGGGTTTAGCTTCCTTTTTAAGGTAGATGAGTCTTGTGTTTGGAGACATCAGGGTGAACGAAAAGTCAGA
GTACAGGATGAAGACATGGAGACACTGGCAAGTTGTACAAGTGAACTCATATCAGAAGAAATGGAACAATTAGATGGAGGTGACACGAGC
AGTGATGAGGATAAAGAAGAACATGAAACTCCTGTGGAAGTAGAACTCATGACTCAGGTTGACCAAGAGGATATCACTCTTCAGAGTGGC
AGAGATGAACTAAATGAGGAGCTCATTCAGGAAGAAAGCTCTGAAGACGAAGGAGAATATGAAGAGGTTAGAAAAGATCAGGATTCTGTT
GGTGAAATGAAGGATGAAGGGGAAGAGACATTAAATTATCCTGATACTACCATTGACTTGTCTCACCTTCAACCCCAAAGGTCCATCCAG
AAATTGGCTTCAAAAGAGGAATCTTCTAATTCTAGTGACAGTAAATCACAGAGCCGGAGACATTTGTCAGCCAAGGAAAGAAGGGAAATG
AAAAAGAAAAAACTTCCAAGTGACTCAGGAGATTTAGAAGCGTTAGAGGGAAAGGATAAAGAAAAAGAAAGTACTGTACACATTGAAACT
CATCAGAACACAAGCAAAAATGTTGCGGCTGTGCAGCCAATGAAACGAGGACAAAAGAGTAAAATGAAAAAAATGAAAGAAAAATACAAA
GACCAGGATGAAGAAGACCGTGAACTTATCATGAAGTTGCTGGGGTCTGCAGGTTCAAACAAAGAAGAAAAAGGGAAGAAGGGGAAGAAA
GGAAAAACAAAGGACGAACCTGTGAAGAAACAGCCCCAGAAACCTAGAGGTGGACAGAGGGTCTCTGACAACATTAAGAAAGAAACTCCG
TTCCTTGAGGTTATAACTCATGAGTTACAAGACTTTGCTGTAGATGATCCACATGATGACAAGGAAGAGCAAGATCTGGATCAACAGGGA
AATGAGGAAAACCTATTTGATTCTTTGACAGGCCAGCCACATCCTGAAGATGTACTACTGTTTGCCATTCCAATATGTGCCCCTTACACC
ACCATGACAAACTACAAATATAAAGTGAAACTTACTCCTGGAGTGCAGAAAAAGGGAAAAGCTGCAAAAACAGCCTTGAATAGTTTCATG
CATTCCAAAGAAGCAACAGCAAGAGAAAAAGACTTATTCCGCAGCGTAAAGGACACAGATTTATCAAGAAACATTCCTGGCAAAGTGAAA
GTGTCTGCACCCAATCTTCTGAATGTAAAAAGGAAATAGCTGAAATGAAATTCTAAAATATTTGAGAAGAGCCAATTTTATAGCCTTTTG
GAAGTTCAAAGATGAAAGCACCATGTATCAGGATTTCCGCATTATAAAAATGAACTAAACATTGCCTTGCTATATTCACCAAAAGGACTT
ACTTCTTGTTTTTTCCCAGTTTTATATAGAGGAAACACTGTCTATGATAGGATTTCCAAAAGTATTTGTGGACAGTTAAATGCTAATTAA
TATACATCTGTAGTTATTCTACATTTTCTTGAAATTTGGGAGGTTAATACCAAGTATTCATTTCATGATGTAAAGAAACTGAACAGTGAA
GTGGCTTGATTGCTTAAACTATTGACTTGGTAAGTCTACTGTATATAACATCTAATATATATATTACAGGCCAAATGAACTAAACATTGC
CTTGCTATATTCACCAAAAGGACTTAATTCTTGTTTTTTTCCCAGTTTTATATAGAGGAAACACTATGATAGGATTTCCTAAAGTATTTG
TGGACAGTTAAATGCTAATTATATACATCTGTAGTTATTCTACATTTTCTTGAAATTTGGGAGGTTAATACCAAGTATTCATTTCATGAT
GTAAAGAAACTGAACAGTGAAGTGGCTTGATTGCTTAAACTATTGACTTGGTAAGTCTACTGTATATAACATCTAATATATATATATTAT
AGGCCAGCTACAAGGGGTTTAAATATTTAGGATTGTGTCTTGAAAACTAAGTATTGGAGTGGATTTTCTTCTGCTTTCATTGATACTTGT
CAGAAAAAAATATTAGACCAAAATGTAAAATATAAGTAATAATTCTCATGACTCAGCTTAATCATTTCTATTCATTTGTAGACCTTCAGG
TTTGATCTTAATTTTTTCCTTGTAATCTGATTCAGTTCTGTACCATTTTAATTTCCACCTTTAGTAATTAATTACCAATATAGCACGTTA
GAGTATCTTAACCTATAATACCAGAAGCGCATTTTAGGCTTACCACTAAAGACTCTAACCCACTTTTCCTCTGTCTCTTAACAGAATGGA
AAATGATGTCATCATTATTTCCATTCCTTCATGAGCTATAAAACCTATTAATTAAAAAAAAACTTTTTAATTGACTGGACAGCACCTGCC
TGTATTCAGCATGACCACTTGCTCCAGCCCCTACACTGAAGCATTAAGGTCAAAGTACTGAACAGTTGTTGGTCCCTCCACACTTTGTTT
TTCCAGCTTCGTCATAATGTGAATATTAATGTTTAAAAAAAAAAACCTTTATTATATTGTATTTACAACACTAGGTTACATAACTATAGA

>59159_59159_1_NIN-NEMF_NIN_chr14_51273455_ENST00000324330_NEMF_chr14_50292673_ENST00000298310_length(amino acids)=588AA_BP=8
MKNTFKNQAFKSAEKKTKQTLKEVQTVTSIQKARKVYWFEKFLWFISSENYLIIGGRDQQQNEIIVKRYLTPGDIYVHADLHGATSCVIK
NPTGEPIPPRTLTEAGTMALCYSAAWDARVITSAWWVYHHQVSKTAPTGEYLTTGSFMIRGKKNFLPPSYLMMGFSFLFKVDESCVWRHQ
GERKVRVQDEDMETLASCTSELISEEMEQLDGGDTSSDEDKEEHETPVEVELMTQVDQEDITLQSGRDELNEELIQEESSEDEGEYEEVR
KDQDSVGEMKDEGEETLNYPDTTIDLSHLQPQRSIQKLASKEESSNSSDSKSQSRRHLSAKERREMKKKKLPSDSGDLEALEGKDKEKES
TVHIETHQNTSKNVAAVQPMKRGQKSKMKKMKEKYKDQDEEDRELIMKLLGSAGSNKEEKGKKGKKGKTKDEPVKKQPQKPRGGQRVSDN
IKKETPFLEVITHELQDFAVDDPHDDKEEQDLDQQGNEENLFDSLTGQPHPEDVLLFAIPICAPYTTMTNYKYKVKLTPGVQKKGKAAKT

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>59159_59159_2_NIN-NEMF_NIN_chr14_51273455_ENST00000382043_NEMF_chr14_50292673_ENST00000298310_length(transcript)=3402nt_BP=302nt
GAGAGACCGACAGAAGGTGAGCACTGTGGGCTATGGGATGGATGAGGTGGAGCAGGACCAGCATGAGGCCCGACTCAAGGAGCTGTTTGA
CAGTTTTGACACGACGGGCACAGGGTCCCTGGGGCAGGAGGAACTCACCGACCTTTGCCACATGTTGAGCTTGGAGGAGGTGGCCCCAGT
GCTGCAGCAGACATTACTTCAGGACAACCTCTTGGGCAGGGTACATTTTGACCAATTTAAAGAAGCATTAATACTCATCTTGTCCAGAAC
TCTGTCAAATGAAGAACACTTTCAAGAACCAGGCATTCAAGTCAGCAGAAAAGAAAACAAAGCAAACATTAAAAGAAGTTCAGACTGTTA
CCTCTATTCAAAAAGCAAGAAAAGTATATTGGTTTGAGAAATTTCTGTGGTTCATTAGCTCAGAGAACTATCTAATTATAGGTGGACGAG
ATCAGCAACAGAATGAAATAATTGTGAAAAGATACTTGACACCAGGAGACATTTATGTACATGCTGATCTTCATGGAGCTACTAGCTGTG
TAATTAAGAATCCAACAGGAGAACCCATCCCCCCACGGACCTTGACTGAAGCTGGCACAATGGCACTTTGCTACAGTGCTGCTTGGGATG
CACGAGTTATCACTAGTGCTTGGTGGGTGTACCATCATCAGGTATCTAAAACAGCACCAACTGGAGAATATTTGACAACAGGAAGCTTCA
TGATAAGAGGAAAAAAGAATTTTCTTCCTCCCTCATATCTAATGATGGGGTTTAGCTTCCTTTTTAAGGTAGATGAGTCTTGTGTTTGGA
GACATCAGGGTGAACGAAAAGTCAGAGTACAGGATGAAGACATGGAGACACTGGCAAGTTGTACAAGTGAACTCATATCAGAAGAAATGG
AACAATTAGATGGAGGTGACACGAGCAGTGATGAGGATAAAGAAGAACATGAAACTCCTGTGGAAGTAGAACTCATGACTCAGGTTGACC
AAGAGGATATCACTCTTCAGAGTGGCAGAGATGAACTAAATGAGGAGCTCATTCAGGAAGAAAGCTCTGAAGACGAAGGAGAATATGAAG
AGGTTAGAAAAGATCAGGATTCTGTTGGTGAAATGAAGGATGAAGGGGAAGAGACATTAAATTATCCTGATACTACCATTGACTTGTCTC
ACCTTCAACCCCAAAGGTCCATCCAGAAATTGGCTTCAAAAGAGGAATCTTCTAATTCTAGTGACAGTAAATCACAGAGCCGGAGACATT
TGTCAGCCAAGGAAAGAAGGGAAATGAAAAAGAAAAAACTTCCAAGTGACTCAGGAGATTTAGAAGCGTTAGAGGGAAAGGATAAAGAAA
AAGAAAGTACTGTACACATTGAAACTCATCAGAACACAAGCAAAAATGTTGCGGCTGTGCAGCCAATGAAACGAGGACAAAAGAGTAAAA
TGAAAAAAATGAAAGAAAAATACAAAGACCAGGATGAAGAAGACCGTGAACTTATCATGAAGTTGCTGGGGTCTGCAGGTTCAAACAAAG
AAGAAAAAGGGAAGAAGGGGAAGAAAGGAAAAACAAAGGACGAACCTGTGAAGAAACAGCCCCAGAAACCTAGAGGTGGACAGAGGGTCT
CTGACAACATTAAGAAAGAAACTCCGTTCCTTGAGGTTATAACTCATGAGTTACAAGACTTTGCTGTAGATGATCCACATGATGACAAGG
AAGAGCAAGATCTGGATCAACAGGGAAATGAGGAAAACCTATTTGATTCTTTGACAGGCCAGCCACATCCTGAAGATGTACTACTGTTTG
CCATTCCAATATGTGCCCCTTACACCACCATGACAAACTACAAATATAAAGTGAAACTTACTCCTGGAGTGCAGAAAAAGGGAAAAGCTG
CAAAAACAGCCTTGAATAGTTTCATGCATTCCAAAGAAGCAACAGCAAGAGAAAAAGACTTATTCCGCAGCGTAAAGGACACAGATTTAT
CAAGAAACATTCCTGGCAAAGTGAAAGTGTCTGCACCCAATCTTCTGAATGTAAAAAGGAAATAGCTGAAATGAAATTCTAAAATATTTG
AGAAGAGCCAATTTTATAGCCTTTTGGAAGTTCAAAGATGAAAGCACCATGTATCAGGATTTCCGCATTATAAAAATGAACTAAACATTG
CCTTGCTATATTCACCAAAAGGACTTACTTCTTGTTTTTTCCCAGTTTTATATAGAGGAAACACTGTCTATGATAGGATTTCCAAAAGTA
TTTGTGGACAGTTAAATGCTAATTAATATACATCTGTAGTTATTCTACATTTTCTTGAAATTTGGGAGGTTAATACCAAGTATTCATTTC
ATGATGTAAAGAAACTGAACAGTGAAGTGGCTTGATTGCTTAAACTATTGACTTGGTAAGTCTACTGTATATAACATCTAATATATATAT
TACAGGCCAAATGAACTAAACATTGCCTTGCTATATTCACCAAAAGGACTTAATTCTTGTTTTTTTCCCAGTTTTATATAGAGGAAACAC
TATGATAGGATTTCCTAAAGTATTTGTGGACAGTTAAATGCTAATTATATACATCTGTAGTTATTCTACATTTTCTTGAAATTTGGGAGG
TTAATACCAAGTATTCATTTCATGATGTAAAGAAACTGAACAGTGAAGTGGCTTGATTGCTTAAACTATTGACTTGGTAAGTCTACTGTA
TATAACATCTAATATATATATATTATAGGCCAGCTACAAGGGGTTTAAATATTTAGGATTGTGTCTTGAAAACTAAGTATTGGAGTGGAT
TTTCTTCTGCTTTCATTGATACTTGTCAGAAAAAAATATTAGACCAAAATGTAAAATATAAGTAATAATTCTCATGACTCAGCTTAATCA
TTTCTATTCATTTGTAGACCTTCAGGTTTGATCTTAATTTTTTCCTTGTAATCTGATTCAGTTCTGTACCATTTTAATTTCCACCTTTAG
TAATTAATTACCAATATAGCACGTTAGAGTATCTTAACCTATAATACCAGAAGCGCATTTTAGGCTTACCACTAAAGACTCTAACCCACT
TTTCCTCTGTCTCTTAACAGAATGGAAAATGATGTCATCATTATTTCCATTCCTTCATGAGCTATAAAACCTATTAATTAAAAAAAAACT
TTTTAATTGACTGGACAGCACCTGCCTGTATTCAGCATGACCACTTGCTCCAGCCCCTACACTGAAGCATTAAGGTCAAAGTACTGAACA
GTTGTTGGTCCCTCCACACTTTGTTTTTCCAGCTTCGTCATAATGTGAATATTAATGTTTAAAAAAAAAAACCTTTATTATATTGTATTT

>59159_59159_2_NIN-NEMF_NIN_chr14_51273455_ENST00000382043_NEMF_chr14_50292673_ENST00000298310_length(amino acids)=588AA_BP=8
MKNTFKNQAFKSAEKKTKQTLKEVQTVTSIQKARKVYWFEKFLWFISSENYLIIGGRDQQQNEIIVKRYLTPGDIYVHADLHGATSCVIK
NPTGEPIPPRTLTEAGTMALCYSAAWDARVITSAWWVYHHQVSKTAPTGEYLTTGSFMIRGKKNFLPPSYLMMGFSFLFKVDESCVWRHQ
GERKVRVQDEDMETLASCTSELISEEMEQLDGGDTSSDEDKEEHETPVEVELMTQVDQEDITLQSGRDELNEELIQEESSEDEGEYEEVR
KDQDSVGEMKDEGEETLNYPDTTIDLSHLQPQRSIQKLASKEESSNSSDSKSQSRRHLSAKERREMKKKKLPSDSGDLEALEGKDKEKES
TVHIETHQNTSKNVAAVQPMKRGQKSKMKKMKEKYKDQDEEDRELIMKLLGSAGSNKEEKGKKGKKGKTKDEPVKKQPQKPRGGQRVSDN
IKKETPFLEVITHELQDFAVDDPHDDKEEQDLDQQGNEENLFDSLTGQPHPEDVLLFAIPICAPYTTMTNYKYKVKLTPGVQKKGKAAKT

--------------------------------------------------------------
>59159_59159_3_NIN-NEMF_NIN_chr14_51273455_ENST00000389868_NEMF_chr14_50292673_ENST00000298310_length(transcript)=3556nt_BP=456nt
CCGAGCCGGGAGCCGAGCGCGCTGGGCGCGGCCGTCCCGCTGCCGCCGCCAAGCCCGGAGTGCGCCAGCGGCCATGGTTCCCGCGGCGGC
GCCGGGCGCCTGAGCCCCGGGACGCAAGCGCTGGAGGCGGGCTGCCGGCTGTGCGGGCGCTCCGGAGAGACCGACAGAAGGTGAGCACTG
TGGGCTATGGGATGGATGAGGTGGAGCAGGACCAGCATGAGGCCCGACTCAAGGAGCTGTTTGACAGTTTTGACACGACGGGCACAGGGT
CCCTGGGGCAGGAGGAACTCACCGACCTTTGCCACATGTTGAGCTTGGAGGAGGTGGCCCCAGTGCTGCAGCAGACATTACTTCAGGACA
ACCTCTTGGGCAGGGTACATTTTGACCAATTTAAAGAAGCATTAATACTCATCTTGTCCAGAACTCTGTCAAATGAAGAACACTTTCAAG
AACCAGGCATTCAAGTCAGCAGAAAAGAAAACAAAGCAAACATTAAAAGAAGTTCAGACTGTTACCTCTATTCAAAAAGCAAGAAAAGTA
TATTGGTTTGAGAAATTTCTGTGGTTCATTAGCTCAGAGAACTATCTAATTATAGGTGGACGAGATCAGCAACAGAATGAAATAATTGTG
AAAAGATACTTGACACCAGGAGACATTTATGTACATGCTGATCTTCATGGAGCTACTAGCTGTGTAATTAAGAATCCAACAGGAGAACCC
ATCCCCCCACGGACCTTGACTGAAGCTGGCACAATGGCACTTTGCTACAGTGCTGCTTGGGATGCACGAGTTATCACTAGTGCTTGGTGG
GTGTACCATCATCAGGTATCTAAAACAGCACCAACTGGAGAATATTTGACAACAGGAAGCTTCATGATAAGAGGAAAAAAGAATTTTCTT
CCTCCCTCATATCTAATGATGGGGTTTAGCTTCCTTTTTAAGGTAGATGAGTCTTGTGTTTGGAGACATCAGGGTGAACGAAAAGTCAGA
GTACAGGATGAAGACATGGAGACACTGGCAAGTTGTACAAGTGAACTCATATCAGAAGAAATGGAACAATTAGATGGAGGTGACACGAGC
AGTGATGAGGATAAAGAAGAACATGAAACTCCTGTGGAAGTAGAACTCATGACTCAGGTTGACCAAGAGGATATCACTCTTCAGAGTGGC
AGAGATGAACTAAATGAGGAGCTCATTCAGGAAGAAAGCTCTGAAGACGAAGGAGAATATGAAGAGGTTAGAAAAGATCAGGATTCTGTT
GGTGAAATGAAGGATGAAGGGGAAGAGACATTAAATTATCCTGATACTACCATTGACTTGTCTCACCTTCAACCCCAAAGGTCCATCCAG
AAATTGGCTTCAAAAGAGGAATCTTCTAATTCTAGTGACAGTAAATCACAGAGCCGGAGACATTTGTCAGCCAAGGAAAGAAGGGAAATG
AAAAAGAAAAAACTTCCAAGTGACTCAGGAGATTTAGAAGCGTTAGAGGGAAAGGATAAAGAAAAAGAAAGTACTGTACACATTGAAACT
CATCAGAACACAAGCAAAAATGTTGCGGCTGTGCAGCCAATGAAACGAGGACAAAAGAGTAAAATGAAAAAAATGAAAGAAAAATACAAA
GACCAGGATGAAGAAGACCGTGAACTTATCATGAAGTTGCTGGGGTCTGCAGGTTCAAACAAAGAAGAAAAAGGGAAGAAGGGGAAGAAA
GGAAAAACAAAGGACGAACCTGTGAAGAAACAGCCCCAGAAACCTAGAGGTGGACAGAGGGTCTCTGACAACATTAAGAAAGAAACTCCG
TTCCTTGAGGTTATAACTCATGAGTTACAAGACTTTGCTGTAGATGATCCACATGATGACAAGGAAGAGCAAGATCTGGATCAACAGGGA
AATGAGGAAAACCTATTTGATTCTTTGACAGGCCAGCCACATCCTGAAGATGTACTACTGTTTGCCATTCCAATATGTGCCCCTTACACC
ACCATGACAAACTACAAATATAAAGTGAAACTTACTCCTGGAGTGCAGAAAAAGGGAAAAGCTGCAAAAACAGCCTTGAATAGTTTCATG
CATTCCAAAGAAGCAACAGCAAGAGAAAAAGACTTATTCCGCAGCGTAAAGGACACAGATTTATCAAGAAACATTCCTGGCAAAGTGAAA
GTGTCTGCACCCAATCTTCTGAATGTAAAAAGGAAATAGCTGAAATGAAATTCTAAAATATTTGAGAAGAGCCAATTTTATAGCCTTTTG
GAAGTTCAAAGATGAAAGCACCATGTATCAGGATTTCCGCATTATAAAAATGAACTAAACATTGCCTTGCTATATTCACCAAAAGGACTT
ACTTCTTGTTTTTTCCCAGTTTTATATAGAGGAAACACTGTCTATGATAGGATTTCCAAAAGTATTTGTGGACAGTTAAATGCTAATTAA
TATACATCTGTAGTTATTCTACATTTTCTTGAAATTTGGGAGGTTAATACCAAGTATTCATTTCATGATGTAAAGAAACTGAACAGTGAA
GTGGCTTGATTGCTTAAACTATTGACTTGGTAAGTCTACTGTATATAACATCTAATATATATATTACAGGCCAAATGAACTAAACATTGC
CTTGCTATATTCACCAAAAGGACTTAATTCTTGTTTTTTTCCCAGTTTTATATAGAGGAAACACTATGATAGGATTTCCTAAAGTATTTG
TGGACAGTTAAATGCTAATTATATACATCTGTAGTTATTCTACATTTTCTTGAAATTTGGGAGGTTAATACCAAGTATTCATTTCATGAT
GTAAAGAAACTGAACAGTGAAGTGGCTTGATTGCTTAAACTATTGACTTGGTAAGTCTACTGTATATAACATCTAATATATATATATTAT
AGGCCAGCTACAAGGGGTTTAAATATTTAGGATTGTGTCTTGAAAACTAAGTATTGGAGTGGATTTTCTTCTGCTTTCATTGATACTTGT
CAGAAAAAAATATTAGACCAAAATGTAAAATATAAGTAATAATTCTCATGACTCAGCTTAATCATTTCTATTCATTTGTAGACCTTCAGG
TTTGATCTTAATTTTTTCCTTGTAATCTGATTCAGTTCTGTACCATTTTAATTTCCACCTTTAGTAATTAATTACCAATATAGCACGTTA
GAGTATCTTAACCTATAATACCAGAAGCGCATTTTAGGCTTACCACTAAAGACTCTAACCCACTTTTCCTCTGTCTCTTAACAGAATGGA
AAATGATGTCATCATTATTTCCATTCCTTCATGAGCTATAAAACCTATTAATTAAAAAAAAACTTTTTAATTGACTGGACAGCACCTGCC
TGTATTCAGCATGACCACTTGCTCCAGCCCCTACACTGAAGCATTAAGGTCAAAGTACTGAACAGTTGTTGGTCCCTCCACACTTTGTTT
TTCCAGCTTCGTCATAATGTGAATATTAATGTTTAAAAAAAAAAACCTTTATTATATTGTATTTACAACACTAGGTTACATAACTATAGA

>59159_59159_3_NIN-NEMF_NIN_chr14_51273455_ENST00000389868_NEMF_chr14_50292673_ENST00000298310_length(amino acids)=588AA_BP=8
MKNTFKNQAFKSAEKKTKQTLKEVQTVTSIQKARKVYWFEKFLWFISSENYLIIGGRDQQQNEIIVKRYLTPGDIYVHADLHGATSCVIK
NPTGEPIPPRTLTEAGTMALCYSAAWDARVITSAWWVYHHQVSKTAPTGEYLTTGSFMIRGKKNFLPPSYLMMGFSFLFKVDESCVWRHQ
GERKVRVQDEDMETLASCTSELISEEMEQLDGGDTSSDEDKEEHETPVEVELMTQVDQEDITLQSGRDELNEELIQEESSEDEGEYEEVR
KDQDSVGEMKDEGEETLNYPDTTIDLSHLQPQRSIQKLASKEESSNSSDSKSQSRRHLSAKERREMKKKKLPSDSGDLEALEGKDKEKES
TVHIETHQNTSKNVAAVQPMKRGQKSKMKKMKEKYKDQDEEDRELIMKLLGSAGSNKEEKGKKGKKGKTKDEPVKKQPQKPRGGQRVSDN
IKKETPFLEVITHELQDFAVDDPHDDKEEQDLDQQGNEENLFDSLTGQPHPEDVLLFAIPICAPYTTMTNYKYKVKLTPGVQKKGKAAKT

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Fusion Gene PPI Analysis for NIN-NEMF


check button Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in

ChiPPI page.


check button Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160)
HgeneHgene's interactorsTgeneTgene's interactors


check button - Retained PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenStill interaction with


check button - Lost PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


check button - Retained PPIs, but lost function due to frame-shift fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


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Related Drugs for NIN-NEMF


check button Drugs targeting genes involved in this fusion gene.
(DrugBank Version 5.1.8 2021-05-08)
PartnerGeneUniProtAccDrugBank IDDrug nameDrug activityDrug typeDrug status

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Related Diseases for NIN-NEMF


check button Diseases associated with fusion partners.
(DisGeNet 4.0)
PartnerGeneDisease IDDisease name# pubmedsSource