FusionGDB Logo

Home

Download

Statistics

Examples

Help

Contact
Center for Computational Systems Medicine
leaf

Fusion Gene Summary

leaf

Fusion Gene ORF analysis

leaf

Fusion Genomic Features

leaf

Fusion Protein Features

leaf

Fusion Gene Sequence

leaf

Fusion Gene PPI analysis

leaf

Related Drugs

leaf

Related Diseases

Fusion gene:NIPBL-NUP155 (FusionGDB2 ID:59208)

Fusion Gene Summary for NIPBL-NUP155

check button Fusion gene summary
Fusion gene informationFusion gene name: NIPBL-NUP155
Fusion gene ID: 59208
HgeneTgene
Gene symbol

NIPBL

NUP155

Gene ID

25836

9631

Gene nameNIPBL cohesin loading factornucleoporin 155
SynonymsCDLS|CDLS1|IDN3|IDN3-B|Scc2ATFB15|N155
Cytomap

5p13.2

5p13.2

Type of geneprotein-codingprotein-coding
Descriptionnipped-B-like proteinNipped-B homologSCC2 homologdelanginsister chromatid cohesion 2 homolognuclear pore complex protein Nup155155 kDa nucleoporinnucleoporin 155kDnucleoporin 155kDa
Modification date2020031320200329
UniProtAcc

Q6KC79

.
Ensembl transtripts involved in fusion geneENST00000282516, ENST00000448238, 
ENST00000504430, 		ENST00000502533, 
ENST00000513532, ENST00000231498, 
ENST00000381843, 
Fusion gene scores* DoF score26 X 13 X 16=54085 X 7 X 5=175
# samples 437
** MAII scorelog2(43/5408*10)=-3.65268658669272
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0		log2(7/175*10)=-1.32192809488736
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0
Context

PubMed: NIPBL [Title/Abstract] AND NUP155 [Title/Abstract] AND fusion [Title/Abstract]

Most frequent breakpointNIPBL(36877280)-NUP155(37309369), # samples:2
Anticipated loss of major functional domain due to fusion event.
* DoF score (Degree of Frequency) = # partners X # break points X # cancer types
** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)

check button Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez
PartnerGeneGO IDGO termPubMed ID
HgeneNIPBL

GO:0000122

negative regulation of transcription by RNA polymerase II

18854353

HgeneNIPBL

GO:0031065

positive regulation of histone deacetylation

18854353

HgeneNIPBL

GO:0045892

negative regulation of transcription, DNA-templated

18854353

HgeneNIPBL

GO:0071921

cohesin loading

22628566

TgeneNUP155

GO:0006998

nuclear envelope organization

19070573


check buttonFusion gene breakpoints across NIPBL (5'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check buttonFusion gene breakpoints across NUP155 (3'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check button Fusion gene information from two resources (ChiTars 5.0 and ChimerDB 4.0)
* All genome coordinats were lifted-over on hg19.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
SourceDiseaseSampleHgeneHchrHbpHstrandTgeneTchrTbpTstrand
ChimerDB4BRCATCGA-BH-A1FMNIPBLchr5

37027514

+NUP155chr5

37310845

-
ChimerDB4SKCMTCGA-D3-A1Q3-06ANIPBLchr5

36877280

-NUP155chr5

37309369

-
ChimerDB4SKCMTCGA-D3-A1Q3-06ANIPBLchr5

36877280

+NUP155chr5

37309369

-
ChimerDB4SKCMTCGA-D3-A1Q3-06ANIPBLchr5

36877280

+NUP155chr5

37310845

-


Top

Fusion Gene ORF analysis for NIPBL-NUP155

check button Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
ORFHenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrand
5CDS-intronENST00000282516ENST00000502533NIPBLchr5

37027514

+NUP155chr5

37310845

-
5CDS-intronENST00000282516ENST00000513532NIPBLchr5

37027514

+NUP155chr5

37310845

-
5CDS-intronENST00000448238ENST00000502533NIPBLchr5

37027514

+NUP155chr5

37310845

-
5CDS-intronENST00000448238ENST00000513532NIPBLchr5

37027514

+NUP155chr5

37310845

-
5UTR-3CDSENST00000282516ENST00000231498NIPBLchr5

36877280

+NUP155chr5

37309369

-
5UTR-3CDSENST00000282516ENST00000231498NIPBLchr5

36877280

+NUP155chr5

37310845

-
5UTR-3CDSENST00000282516ENST00000381843NIPBLchr5

36877280

+NUP155chr5

37309369

-
5UTR-3CDSENST00000282516ENST00000381843NIPBLchr5

36877280

+NUP155chr5

37310845

-
5UTR-3CDSENST00000282516ENST00000513532NIPBLchr5

36877280

+NUP155chr5

37309369

-
5UTR-3CDSENST00000448238ENST00000231498NIPBLchr5

36877280

+NUP155chr5

37309369

-
5UTR-3CDSENST00000448238ENST00000231498NIPBLchr5

36877280

+NUP155chr5

37310845

-
5UTR-3CDSENST00000448238ENST00000381843NIPBLchr5

36877280

+NUP155chr5

37309369

-
5UTR-3CDSENST00000448238ENST00000381843NIPBLchr5

36877280

+NUP155chr5

37310845

-
5UTR-3CDSENST00000448238ENST00000513532NIPBLchr5

36877280

+NUP155chr5

37309369

-
5UTR-5UTRENST00000282516ENST00000502533NIPBLchr5

36877280

+NUP155chr5

37309369

-
5UTR-5UTRENST00000448238ENST00000502533NIPBLchr5

36877280

+NUP155chr5

37309369

-
5UTR-intronENST00000282516ENST00000502533NIPBLchr5

36877280

+NUP155chr5

37310845

-
5UTR-intronENST00000282516ENST00000513532NIPBLchr5

36877280

+NUP155chr5

37310845

-
5UTR-intronENST00000448238ENST00000502533NIPBLchr5

36877280

+NUP155chr5

37310845

-
5UTR-intronENST00000448238ENST00000513532NIPBLchr5

36877280

+NUP155chr5

37310845

-
In-frameENST00000282516ENST00000231498NIPBLchr5

37027514

+NUP155chr5

37310845

-
In-frameENST00000282516ENST00000381843NIPBLchr5

37027514

+NUP155chr5

37310845

-
In-frameENST00000448238ENST00000231498NIPBLchr5

37027514

+NUP155chr5

37310845

-
In-frameENST00000448238ENST00000381843NIPBLchr5

37027514

+NUP155chr5

37310845

-
intron-3CDSENST00000504430ENST00000231498NIPBLchr5

37027514

+NUP155chr5

37310845

-
intron-3CDSENST00000504430ENST00000231498NIPBLchr5

36877280

+NUP155chr5

37309369

-
intron-3CDSENST00000504430ENST00000231498NIPBLchr5

36877280

+NUP155chr5

37310845

-
intron-3CDSENST00000504430ENST00000381843NIPBLchr5

37027514

+NUP155chr5

37310845

-
intron-3CDSENST00000504430ENST00000381843NIPBLchr5

36877280

+NUP155chr5

37309369

-
intron-3CDSENST00000504430ENST00000381843NIPBLchr5

36877280

+NUP155chr5

37310845

-
intron-3CDSENST00000504430ENST00000513532NIPBLchr5

36877280

+NUP155chr5

37309369

-
intron-5UTRENST00000504430ENST00000502533NIPBLchr5

36877280

+NUP155chr5

37309369

-
intron-intronENST00000504430ENST00000502533NIPBLchr5

37027514

+NUP155chr5

37310845

-
intron-intronENST00000504430ENST00000502533NIPBLchr5

36877280

+NUP155chr5

37310845

-
intron-intronENST00000504430ENST00000513532NIPBLchr5

37027514

+NUP155chr5

37310845

-
intron-intronENST00000504430ENST00000513532NIPBLchr5

36877280

+NUP155chr5

37310845

-

check buttonORFfinder result based on the fusion transcript sequence of in-frame fusion genes.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandSeq length
(transcript)		BP loci
(transcript)		Predicted start
(transcript)		Predicted stop
(transcript)		Seq length
(amino acids)
ENST00000282516NIPBLchr537027514+ENST00000231498NUP155chr537310845-11864636149981002533
ENST00000282516NIPBLchr537027514+ENST00000381843NUP155chr537310845-8162636149981002533
ENST00000448238NIPBLchr537027514+ENST00000231498NUP155chr537310845-11833633046880692533
ENST00000448238NIPBLchr537027514+ENST00000381843NUP155chr537310845-8131633046880692533

check buttonDeepORF prediction of the coding potential based on the fusion transcript sequence of in-frame fusion genes. DeepORF is a coding potential classifier based on convolutional neural network by comparing the real Ribo-seq data. If the no-coding score < 0.5 and coding score > 0.5, then the in-frame fusion transcript is predicted as being likely translated.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandNo-coding scoreCoding score
ENST00000282516ENST00000231498NIPBLchr537027514+NUP155chr537310845-0.0003879470.99961203
ENST00000282516ENST00000381843NIPBLchr537027514+NUP155chr537310845-0.0006926220.9993074
ENST00000448238ENST00000231498NIPBLchr537027514+NUP155chr537310845-0.0003808020.9996191
ENST00000448238ENST00000381843NIPBLchr537027514+NUP155chr537310845-0.0006841680.99931586

Top

Fusion Genomic Features for NIPBL-NUP155


check buttonFusionAI prediction of the potential fusion gene breakpoint based on the pre-mature RNA sequence context (+/- 5kb of individual partner genes, total 20kb length sequence). FusionAI is a fusion gene breakpoint classifier based on convolutional neural network by comparing the fusion positive and negative sequence context of ~ 20K fusion gene data. From here, we can have the relative potentency of the 20K genomic sequence how individual sequnce will be likely used as the gene fusion breakpoints.
HgeneHchrHbpHstrandTgeneTchrTbpTstrand1-pp (fusion gene breakpoint)

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions. We integrated a total of 44 different types of human genomic feature loci information across five big categories including virus integration sites, repeats, structural variants, chromatin states, and gene expression regulation. More details are in help page.
genomic feature

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions that are ovelapped with the top 1% feature importance score regions. More details are in help page.

Top

Fusion Protein Features for NIPBL-NUP155


check button Four levels of functional features of fusion genes
Go to FGviewer search page for the most frequent breakpoint (https://ccsmweb.uth.edu/FGviewer/chr5:36877280/chr5:37309369)
- FGviewer provides the online visualization of the retention search of the protein functional features across DNA, RNA, protein, and pathological levels.
- How to search
1. Put your fusion gene symbol.
2. Press the tab key until there will be shown the breakpoint information filled.
4. Go down and press 'Search' tab twice.
4. Go down to have the hyperlink of the search result.
5. Click the hyperlink.
6. See the FGviewer result for your fusion gene.
FGviewer

check buttonMain function of each fusion partner protein. (from UniProt)
HgeneTgene
NIPBL

Q6KC79

.
FUNCTION: Plays an important role in the loading of the cohesin complex on to DNA. Forms a heterodimeric complex (also known as cohesin loading complex) with MAU2/SCC4 which mediates the loading of the cohesin complex onto chromatin (PubMed:22628566, PubMed:28914604). Plays a role in cohesin loading at sites of DNA damage. Its recruitment to double-strand breaks (DSBs) sites occurs in a CBX3-, RNF8- and RNF168-dependent manner whereas its recruitment to UV irradiation-induced DNA damage sites occurs in a ATM-, ATR-, RNF8- and RNF168-dependent manner (PubMed:28167679). Along with ZNF609, promotes cortical neuron migration during brain development by regulating the transcription of crucial genes in this process. Preferentially binds promoters containing paused RNA polymerase II. Up-regulates the expression of SEMA3A, NRP1, PLXND1 and GABBR2 genes, among others (By similarity). {ECO:0000250|UniProtKB:Q6KCD5, ECO:0000269|PubMed:22628566, ECO:0000269|PubMed:28167679, ECO:0000269|PubMed:28914604}.FUNCTION: Transcriptional activator which is required for calcium-dependent dendritic growth and branching in cortical neurons. Recruits CREB-binding protein (CREBBP) to nuclear bodies. Component of the CREST-BRG1 complex, a multiprotein complex that regulates promoter activation by orchestrating a calcium-dependent release of a repressor complex and a recruitment of an activator complex. In resting neurons, transcription of the c-FOS promoter is inhibited by BRG1-dependent recruitment of a phospho-RB1-HDAC1 repressor complex. Upon calcium influx, RB1 is dephosphorylated by calcineurin, which leads to release of the repressor complex. At the same time, there is increased recruitment of CREBBP to the promoter by a CREST-dependent mechanism, which leads to transcriptional activation. The CREST-BRG1 complex also binds to the NR2B promoter, and activity-dependent induction of NR2B expression involves a release of HDAC1 and recruitment of CREBBP (By similarity). {ECO:0000250}.

check buttonRetention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at

download page


* Minus value of BPloci means that the break pointn is located before the CDS.
- In-frame and retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneNIPBLchr5:37027514chr5:37310845ENST00000282516+3247418_46219542805.0Compositional biasNote=Gln-rich
HgeneNIPBLchr5:37027514chr5:37310845ENST00000448238+3246418_46219542698.0Compositional biasNote=Gln-rich
HgeneNIPBLchr5:37027514chr5:37310845ENST00000282516+3247996_100919542805.0MotifPxVxL motif
HgeneNIPBLchr5:37027514chr5:37310845ENST00000448238+3246996_100919542698.0MotifPxVxL motif
HgeneNIPBLchr5:37027514chr5:37310845ENST00000282516+32471767_180519542805.0RepeatNote=HEAT 1
HgeneNIPBLchr5:37027514chr5:37310845ENST00000282516+32471843_188119542805.0RepeatNote=HEAT 2
HgeneNIPBLchr5:37027514chr5:37310845ENST00000448238+32461767_180519542698.0RepeatNote=HEAT 1
HgeneNIPBLchr5:37027514chr5:37310845ENST00000448238+32461843_188119542698.0RepeatNote=HEAT 2

- In-frame and not-retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneNIPBLchr5:37027514chr5:37310845ENST00000282516+32471945_198419542805.0RepeatNote=HEAT 3
HgeneNIPBLchr5:37027514chr5:37310845ENST00000282516+32472227_226719542805.0RepeatNote=HEAT 4
HgeneNIPBLchr5:37027514chr5:37310845ENST00000282516+32472313_235119542805.0RepeatNote=HEAT 5
HgeneNIPBLchr5:37027514chr5:37310845ENST00000448238+32461945_198419542698.0RepeatNote=HEAT 3
HgeneNIPBLchr5:37027514chr5:37310845ENST00000448238+32462227_226719542698.0RepeatNote=HEAT 4
HgeneNIPBLchr5:37027514chr5:37310845ENST00000448238+32462313_235119542698.0RepeatNote=HEAT 5
TgeneNUP155chr5:37027514chr5:37310845ENST000002314982135585_6558121392.0Compositional biasNote=Pro-rich
TgeneNUP155chr5:37027514chr5:37310845ENST000003818432135585_6557531333.0Compositional biasNote=Pro-rich


Top

Fusion Gene Sequence for NIPBL-NUP155


check button For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. To have fusion amino acid sequence, we ran ORFfinder and chose the longest ORF among the all predicted ones.
>59208_59208_1_NIPBL-NUP155_NIPBL_chr5_37027514_ENST00000282516_NUP155_chr5_37310845_ENST00000231498_length(transcript)=11864nt_BP=6361nt
TCCGGTCGGCATTTTGTTCTGAGAGGGAGAGACGGAACGAGAGAGAGACACACACAGGGCTCCTTCCCCCCGCCCTCCCCCCCCTCCCTC
CGTCGGTACCGACTCACCCGACACCACCAAGCCGCAGGGAGGGACGCCCCCGCCGACAGGAGAATTGGTTCCCGGGCCCGCGGCGATGCC
CCCCCGGTAGCTCGGGCCCGTGGTCGGGTGTTTGTGAGTGTTTCTATGTGGGAGAAGGAGGAGGAGGAGGAAGAAGAAGCAACGATTTGT
CTTCTCGGCTGGTCTCCCCCCGGCTCTACATGTTCCCCGCACTGAGGAGACGGAAGAGGAGCCGTAGCCACCCCCCCTCCCGGCCCGGAT
TATAGTCTCTCGCCACAGCGGCCTCGGCCTCCCCTTGGATTCAGACGCCGATTCGCCCAGTGTTTGGGAAATGGGAAGTAATGACAGCTG
GCACCTGAACTAAGTACTTTTATAGGCAACACCATTCCAGAAATTCAGGATGAATGGGGATATGCCCCATGTCCCCATTACTACTCTTGC
GGGGATTGCTAGTCTCACAGACCTCCTGAACCAGCTGCCTCTTCCATCTCCTTTACCTGCTACAACTACAAAGAGCCTTCTCTTTAATGC
ACGAATAGCAGAAGAGGTGAACTGCCTTTTGGCTTGTAGGGATGACAATTTGGTTTCACAGCTTGTCCATAGCCTCAACCAGGTATCAAC
AGATCACATAGAGTTGAAAGATAACCTTGGCAGTGATGACCCAGAAGGTGACATACCAGTCTTGTTGCAGGCCGTCCTGGCAAGGAGTCC
TAATGTTTTCAGGGAGAAAAGCATGCAGAACAGATATGTACAAAGTGGAATGATGATGTCTCAGTATAAACTTTCTCAGAATTCCATGCA
CAGTAGTCCTGCATCTTCCAATTATCAACAAACCACTATCTCACATAGCCCCTCCAGCCGGTTTGTGCCACCACAGACAAGCTCTGGGAA
CAGATTTATGCCACAGCAAAATAGCCCAGTGCCTAGTCCATACGCCCCACAAAGCCCTGCAGGATACATGCCATATTCCCATCCTTCAAG
TTACACAACACATCCACAGATGCAACAAGCATCGGTATCAAGTCCCATTGTTGCAGGTGGTTTGAGAAACATACATGATAATAAAGTTTC
TGGTCCGTTGTCTGGCAATTCAGCTAATCATCATGCTGATAATCCTAGACATGGTTCAAGTGAGGACTACCTACACATGGTGCACAGGCT
AAGTAGTGACGATGGAGATTCTTCAACAATGAGGAATGCTGCATCTTTTCCCTTGAGATCTCCACAGCCAGTATGCTCCCCTGCTGGAAG
TGAAGGAACTCCTAAAGGCTCAAGACCACCTTTAATCCTACAATCTCAGTCTCTACCTTGTTCATCACCTCGAGATGTTCCACCAGATAT
CTTGCTAGATTCTCCAGAAAGAAAACAAAAGAAGCAGAAGAAAATGAAATTAGGCAAGGATGAAAAAGAGCAGAGTGAGAAAGCGGCAAT
GTATGATATAATTAGTTCTCCATCCAAGGACTCTACTAAACTTACATTAAGACTTTCTCGTGTAAGGTCTTCAGACATGGACCAGCAAGA
GGATATGATTTCTGGTGTGGAAAATAGCAATGTTTCAGAAAATGATATTCCTTTTAATGTGCAGTACCCAGGACAGACTTCAAAAACACC
CATTACTCCACAAGATATAAACCGCCCACTAAATGCTGCTCAATGTTTGTCGCAGCAAGAACAAACAGCATTCCTTCCAGCAAATCAAGT
GCCTGTTTTACAACAGAACACTTCAGTTGCTGCAAAACAACCCCAGACTTCTGTGGTACAGAATCAACAACAGATATCACAACAGGGACC
TATATATGATGAAGTGGAATTGGATGCATTGGCTGAAATTGAGCGAATAGAGAGAGAATCAGCTATTGAAAGGGAGCGCTTCTCAAAAGA
AGTTCAAGATAAAGATAAGCCTTTGAAAAAAAGAAAACAAGATTCTTACCCACAGGAGGCTGGGGGTGCTACAGGAGGTAATAGACCAGC
TTCTCAGGAGACGGGTTCTACGGGAAATGGGTCAAGGCCAGCATTAATGGTTAGCATTGATCTTCATCAGGCAGGAAGAGTGGACTCTCA
GGCTTCTATAACTCAGGATTCAGACTCCATAAAAAAGCCTGAAGAAATCAAACAATGTAATGATGCACCTGTTTCTGTTCTTCAGGAAGA
TATTGTTGGAAGTCTTAAATCTACACCAGAAAACCATCCTGAGACACCTAAAAAAAAGTCTGATCCTGAGCTTTCAAAGAGTGAAATGAA
ACAAAGTGAAAGTAGATTAGCAGAATCTAAACCAAATGAAAACCGATTGGTGGAGACAAAATCAAGTGAAAATAAGTTAGAAACTAAAGT
TGAGACCCAAACAGAAGAACTTAAACAGAATGAGAGCAGAACAACTGAATGCAAACAAAACGAGAGCACCATAGTTGAGCCTAAACAAAA
TGAAAATAGACTGTCTGACACAAAACCAAATGACAACAAACAAAATAATGGCAGATCAGAAACAACAAAATCAAGGCCTGAAACCCCAAA
GCAAAAGGGTGAAAGCCGGCCTGAGACTCCAAAACAAAAGAGTGATGGGCATCCTGAAACCCCAAAACAGAAGGGTGATGGAAGGCCTGA
AACTCCAAAGCAAAAAGGTGAGAGCCGCCCTGAAACTCCAAAGCAAAAAAATGAAGGGCGACCTGAAACACCAAAACACAGGCATGACAA
TAGGAGGGATTCTGGAAAGCCATCTACAGAGAAAAAACCTGAAGTGTCTAAACATAAACAAGATACTAAATCTGACTCACCTCGGTTAAA
ATCAGAACGAGCTGAAGCCTTAAAGCAGAGACCTGATGGGCGATCTGTTTCTGAGTCACTAAGACGTGACCATGATAATAAACAAAAATC
AGATGACAGGGGTGAATCAGAGCGACATCGAGGGGATCAGTCTAGGGTTCGAAGACCAGAAACATTGAGATCCTCTAGTAGAAATGAACA
TGGCATTAAATCTGATAGTTCAAAAACTGATAAACTAGAACGAAAACACAGGCATGAATCAGGGGACTCAAGGGAAAGACCATCTTCTGG
GGAACAAAAATCAAGACCTGACAGTCCTCGTGTTAAACAAGGAGATTCTAATAAATCAAGATCTGATAAACTTGGTTTTAAATCACCAAC
TAGTAAAGATGACAAAAGGACAGAGGGTAACAAGAGTAAAGTAGACACTAATAAAGCACACCCTGACAATAAGGCAGAATTTCCAAGTTA
TTTGTTGGGGGGCAGGTCTGGTGCGTTGAAAAATTTTGTCATTCCGAAAATCAAGAGGGATAAAGATGGCAATGTTACTCAGGAGACAAA
GAAAATGGAAATGAAAGGAGAGCCGAAAGACAAAGTAGAAAAAATAGGATTAGTTGAAGATCTAAATAAAGGAGCTAAGCCTGTAGTTGT
GCTACAAAAACTGTCTTTGGATGATGTTCAGAAACTTATTAAAGATAGAGAGGACAAATCAAGAAGTTCCCTTAAACCTATCAAGAATAA
ACCATCAAAGTCAAATAAAGGTAGTATAGATCAATCAGTGTTAAAAGAATTACCCCCTGAACTCCTGGCAGAAATTGAGTCCACCATGCC
ACTTTGTGAACGTGTGAAAATGAACAAACGCAAGCGTAGCACAGTTAATGAAAAGCCAAAATATGCTGAAATCAGTTCAGATGAAGATAA
TGATAGTGATGAAGCTTTTGAATCCTCTAGGAAACGACATAAAAAAGATGATGATAAAGCTTGGGAATATGAAGAGCGTGACAGAAGAAG
CTCTGGGGATCATAGGAGAAGTGGCCACTCTCATGAAGGAAGAAGGAGTTCAGGTGGTGGTCGTTATCGAAACCGAAGTCCGTCAGATTC
TGACATGGAAGATTATTCTCCTCCTCCCAGCCTTAGTGAGGTTGCTAGGAAAATGAAGAAAAAAGAAAAACAGAAGAAAAGGAAAGCATA
TGAACCAAAACTAACACCTGAAGAAATGATGGACTCTTCAACTTTTAAGAGATTCACAGCCTCAATAGAGAATATTTTGGATAATTTGGA
AGATATGGATTTTACTGCGTTTGGTGATGATGATGAAATTCCTCAGGAACTGCTCTTAGGAAAACATCAGCTTAATGAACTTGGCAGTGA
ATCTGCTAAAATAAAAGCAATGGGTATAATGGATAAGCTTTCAACTGACAAAACTGTGAAAGTCTTAAATATCTTGGAGAAGAATATTCA
GGATGGGTCAAAGCTTTCCACTTTGTTAAATCATAATAACGATACTGAAGAAGAAGAAAGGTTATGGAGAGACCTTATTATGGAGAGAGT
TACAAAATCAGCGGATGCTTGTCTTACAACTATCAACATTATGACATCCCCTAACATGCCAAAAGCTGTGTACATTGAGGATGTAATTGA
AAGAGTTATACAGTACACTAAATTTCATTTGCAGAATACACTTTATCCTCAGTATGATCCTGTTTACAGATTAGATCCTCATGGAGGAGG
CTTATTAAGTTCAAAAGCAAAACGGGCTAAATGTTCTACCCATAAGCAGAGAGTAATAGTAATGCTTTATAACAAAGTTTGTGACATTGT
TAGCAGCTTATCAGAATTGCTAGAGATACAACTTCTTACAGACACAACAATTCTTCAGGTTTCATCTATGGGAATAACACCATTTTTTGT
GGAAAATGTCAGTGAACTACAGTTGTGTGCCATTAAGTTAGTCACTGCAGTATTCTCAAGATATGAAAAACATAGGCAGTTAATTTTGGA
AGAAATTTTTACTTCACTTGCAAGATTACCAACCAGCAAGAGGAGTTTAAGGAACTTCAGGTTAAACAGTAGTGATATGGATGGAGAACC
TATGTATATTCAGATGGTTACAGCACTGGTTTTACAACTTATTCAGTGTGTGGTACACTTACCATCATCAGAGAAGGACTCTAATGCAGA
AGAAGATTCAAATAAAAAAATTGACCAGGATGTTGTCATTACTAACTCTTATGAAACAGCTATGCGAACAGCCCAAAACTTCCTCTCCAT
CTTCCTTAAAAAATGTGGTAGTAAGCAAGGTGAAGAAGATTACAGACCACTGTTTGAAAATTTTGTTCAAGACCTTCTTTCAACAGTCAA
TAAGCCTGAATGGCCAGCTGCTGAACTACTCCTTAGTTTGTTAGGGAGACTGTTGGTTCATCAGTTCAGTAACAAGTCAACAGAGATGGC
TTTAAGAGTGGCATCTCTTGATTACCTTGGAACTGTTGCTGCACGGCTAAGAAAAGATGCTGTTACAAGCAAAATGGATCAAGGATCTAT
AGAACGCATTTTAAAACAGGTTTCAGGAGGGGAAGATGAAATCCAACAATTACAAAAAGCATTGCTTGATTACTTGGATGAAAACACTGA
GACTGATCCTTCACTAGTGTTTTCTCGTAAATTCTATATAGCCCAGTGGTTTCGAGACACAACTCTGGAAACAGAAAAAGCAATGAAATC
ACAAAAAGATGAAGAATCATCTGAAGGAACACATCATGCAAAGGAAATTGAGACAACTGGCCAAATTATGCATCGAGCTGAAAACCGAAA
AAAGTTTCTTAGAAGCATTATCAAAACCACACCTTCTCAGTTTAGCACATTAAAGATGAACTCTGATACTGTGGACTATGATGATGCTTG
CTTGATTGTTCGATACTTGGCCTCCATGAGGCCGTTTGCCCAGAGCTTTGATATTTATTTGACACAGATCCTACGAGTTCTTGGTGAAAA
TGCAATTGCTGTTCGAACAAAAGCCATGAAGTGTTTGTCTGAGGTTGTTGCTGTAGACCCCAGTATTCTAGCAAGGCTTGATATGCAACG
AGGTGTTCATGGACGATTGATGGATAATTCGACTAGTGTCCGAGAAGCAGCAGTAGAATTACTAGGTCGATTTGTCCTTTGTCGACCTCA
GCTTGCTGAACAGTATTATGATATGCTGATTGAAAGAATATTGGATACTGGTATCAGTGTCAGGAAAAGAGTAATAAAGATTCTCAGAGA
CATTTGTATTGAACAACCAACATTTCCAAAAATCACAGAAATGTGTGTAAAAATGATTCGCAGAGTCAATGATGAAGAGGGCATTAAGAA
ATTAGTAAATGAAACATTCCAGAAACTCTGGTTTACTCCAACTCCACACAATGACAAAGAAGCAATGACAAGGAAAATTTTAAACATTAC
CGATGTGGTTGCAGCATGCAGAGATACTGGATATGACTGGTTTGAGCAACTGCTTCAAAACGAACTTCAAGAGCAGCTGAAGATCACCAC
CTTTAAAGATCTTGTAATCAGGGACAAAGAACTCACAGGGGCATTAATTGCTTCTCTTATCAACTGCTACATCAGAGATAATGCCGCTGT
TGATGGCATTAGTTTACATTTACAGGATATCTGCCCACTTCTATATAGCACTGATGATGCAATTTGTTCTAAGGCAAATGAGCTTCTCCA
GCGTTCCCGACAAGTTCAAAATAAGACTGAAAAAGAAAGAATGTTAAGGGAATCATTAAAGGAATATCAAAAAATTAGCAATCAAGTGGA
CCTTTCCAATGTTTGTGCTCAGTATAGACAAGTGAGATTTTATGAGGGTGTGGTGGAACTTTCTCTTACGGCTGCAGAGAAAAAAGATCC
TCAAGGTCTTGGGCTTCATTTCTATAAACATGGAGAACCAGAAGAAGACATAGTTGGACTTCAGGCCTTCCAAGAAAGATTAAACAGTTA
CAAATGCATTACAGACACACTTCAAGAACTGGTAAATCAAAGTAAGGCCGCTCCTCAGTCTCCCAGTGTACCCAAAAAACCTGGTCCTCC
AGTGTTGTCATCTGATCCAAATATGCTGAGTAATGAAGAAGCAGGACATCATTTTGAACAAATGCTTAAATTGTCACAGCGATCCAAGGA
TGAGCTCTTTAGTATTGCCCTTTATAATTGGCTAATACAAGTCGACCTTGCAGATAAGCTGCTACAGGTTGCTTCTCCATTTCTGGAGCC
ACATCTAGTCCGAATGGCCAAAGTTGATCAAAACAGAGTTCGTTATATGGATTTACTCTGGCGGTATTACGAGAAGAACAGAAGTTTCAG
TAATGCTGCTCGTGTACTGTCCAGACTGGCTGACATGCATAGCACAGAAATTTCACTTCAGCAGCGACTAGAGTACATTGCTCGAGCCAT
TCTTAGTGCCAAAAGTTCCACTGCCATTTCATCAATAGCTGCCGATGGTGAATTTCTTCATGAATTAGAAGAAAAAATGGAGGTTGCTAG
GATCCAACTTCAGATACAGGAGACACTACAAAGGCAGTATTCCCATCATTCTTCTGTACAGGATGCAGTTTCTCAGCTGGATTCTGAGCT
GATGGACATAACTAAGCTTTATGGGGAATTTGCTGACCCATTTAAACTTGCAGAGTGCAAACTTGCAATAATTCATTGTGCCGGTTATTC
AGACCCTATATTGGTGCAGACACTTTGGCAAGATATCATAGAGAAAGAATTGAGTGACAGTGTGACATTGAGCTCCTCGGATAGAATGCA
TGCTCTTAGTCTCAAGATTGTTCTCCTTGGCAAAATTTATGCTGGCACACCACGCTTCTTTCCTTTAGATTTTATTGTACAGTTTTTAGA
ACAGCAGGTTTGTACTTTGAACTGGGATGTGGGCTTCGTAATACAGACAATGAATGAAATTGGAGTACCATTACCTAGACTACTAGAAGT
TTATGATCAGTTGTTCAAATCACGGGATCCATTCTGGAACAGAATGAAGAAGCCACTGCACCTTTTGGATTGTATACATGTATTATTGAT
AAGATATGTTGAGAATCCCAGCCAAGTTTTAAATTGTGAAAGGAGAAGATTTACAAATCTCTGCCTGGATGCTGTTTGTGGTTACCTTGT
TGAGCTCCAGTCTATGAGCTCGTCAGTAGCAGTACAAGCCATCACTGGGAATTTTAAATCTCTTCAAGCTAAATTAGAACGGCTTCATTA
ATTACTGTGATATACTTTCATCCGTTTTATGATCTGTAAAATAAAAACTCAGCTGGGTCCAGATATCAGGTGTTCTAAATCTAAGAATGT
AAGAACAATCTTAATAGAAATATGTTTTTAATAAGTGGCTAATATCTACAAATAGTACCTTTGCTAAATGAATTCTTTTTTATGACTATT
TTGTTTTTTAGTAATTGGGTGAAAAAACAACTGAAATGAGATTATTTATTATTTTAACATAAGGATTAAAAAAATTTAGAAACTCTTATT
TTGAATTGTACTGCAGGCAGAAATTTCGAATTTATATTATTCATTTTCAAGTTAGTCCAAGGATATTGGCATTAAAACTCCACTAGGCGG
CCAGGCACAGTGACTTACACCTGTAATCCCAGCACTTTGGGAGGCCAAGGTGGGCGAATCACGAGGCCAAGAGTTTGAGACCAACCTGGC
CAACATGGTGAAACCCCATCTCTACTAAAAATACAAAAAAAAATAGCCAGGCGTGGTGGCGGGCGCCTGTAATCCCAGCTACTCGGGAGG
CTGAGGGAGGCGAATCACTTGAACCCGGGAGGCAGAGGTTTCAGTGAGTCAAAATCGCACCATTGCACTCCAGCCCAGGCAACAGGGCGA
GACTCTGTCTCAAAAAACAAAAAAACCTCAAATAGGCTAAGCAGATCCATTCCCATAATAGTGGATTCTAAAACCGTCCTTAAATAGGCA
AATAACTGACTTTTTCAAAACTTTTTTTAGGTGTTGGGTTCACCCTTGAAAGAACTGTCCTCTAACAACTGGTTTTGTCAGTTAAAGCCC
TTGAGAATTGACATAGCTATATACCTGGTTGAGCAGGTGATAAAACTTGTAACTAATGTTGTGTCCTGAAAACCTACACAGGGAGGTACT
GTTTTCCCTTAGTGTCTACCTGGCTGCTTGGCCTTGTGACTACTGATTCCATTAGAGCAGTGGTTCTCAAAGTATGTGCTCCAAACCAGA
AGCATCAGCATCAGCATCAGCATCACCTAGGAATTTGTTAGAAATGCAAATTCTCGAGCCCCAACCCAGACCTACTGAATCAAAAACGTG
GGGGATGAGGCCCTGCTTTCTATGTTTTAACAAGCTCTCCAGGAGATTTTGGTGCATGTCAAATTTGAAAGCCACTGCAGTAAAGGATAC
TGCTACCTTCCATAGTTTATGGACTGAGCTACCTATCTGGCTCCTCCTCTGTGAATAACCACACACACAAATTTTGCCCAAGGCACACAA
TATATAAAGCAAAACTGTTAGTAATGTACTTTTTAATTATTCCTTAACAAAATAGAATAACCAAACCAAATGCTTCAAAGTAATAGCAAC
AAGAGAGAAGAAGAGTGGGAATGACCAGAGCTAACAAAACACTCTATTCCTTTCTCTCTTTTTTTTTTTTTTGGAGACAGAATCTCACCC
TGTAGCCCAGCCTGGAGTGCAGTGGTGCGATCCCGGCTCACTGCAACCTCTGCCTCACAGGTTTGAAGCAATTTGCCTGCCTCAGCCTCT
CGAGTAGCTGGGATTGCAGGTGTGCGCCACCATACCCAGCTAATTTTTGTATTTTTAGTAGAGATGGGTTTCACCATGTTGGCCAGGCTG
GTCTTGAACTCCTGACCTCAAGTGATCTGCCCGCCTCCACCTCCCAAAGTGTTGAGATTACAGACGTGAGCCAATGTGCCTGGCCTATTC
CCTTCTCTCTTTATGCTACCACAAATAATTACCTTCTGTTTATTGTAAGTGATGCATGTCTAACAATTTGTACAATACATTTTGAATATA
TTTTTCCTTCCATTATTGTCTTTTCCCAAGACCATAGGGTTGCCTTCTCTACATTTGTTCTCTTAGAATTCAGCTCCCTTTTCCCTATAA
TCTTCTAATGTAGAATATTTAATAGAATGCCAGAACGTCACTCAGTGGGTACTACTACCTCTTATTTTTCAACTTTTCAGTTTCTTAAGT
TTAGCGTTTTTTGAATATGTAAAGTGAATGTATGCGATACATTAATTCGTTTTATAAATTTAAAATTCTGTCATGTCTACTTAAAAGGAA
GGCCTTGTCTGAATGTTGTAATTTAGGTGTGACTCCAGTTCTGCTAGAGATAAGAACTTCATTTTTGTTTTAAGCACATTTACATACTAG
CAATATGTTGTTATATATACTCAGCTCACAACATTGAAAGTACATGTTTTAAAAGGGCTGTAGGCTTCCATGGTTAGATGGTCTGTTAGA
GTCAGAAATCTGAACACTGTCCTTTTATTCACACAGCATGCTTTGAGAGGTTTTAGGAATTCCAGCCCCACAACAGATGCTTGCAATACC
TTTTGGGGGGTAAGATTCCTAAGAGAGAAGAAATTAGGTCCCCTCATTTTTACCCTTGGAACAGTGTTTCTAAAACTTTCACATTCAGAA
CAATCAGCCGGATAGCCTGTTATGACAGATTCTTGAGTTCCATCTGTAGTGTCATGCTGATCCTGGCAGTCAGTGGATCAGAGTTGGAGT
AGCATTTATCCACTGTATTAGTATACTTTGTACTTGGTGTTTGTTCAACGCATTACTTTTTTGAATTTTTTTGTTTTTTGAAGACAAGGG
CTTGCCCTGGAGTGCAGTGGCATGATCTTGGCTCACTGCAGCCTCGAGCTCCTGGGCTCAACTCAGTCTTCCCACCTCATCCTCTTAAAT
AGCTGGGACTACAGGCACGTGCTGCTACACCCTGCTATTGTCTGTTTGTTTGTTTGAGACTGAGTTTTGCTCTTGTTGCCCAGGCTGGAG
TGCAATGGCACAATCTTGGCTCACCACAGCCTTTTTTATGAGACTGAGTTTTGCTCTTGTTGCCCAGGCTGGAGTGCAATGGCACGATCT
TGGCTCACCACAACCTCCACTTCCTGGGTTCAAGCAATTCTTCTGCCTCAGCCTCCCGAGTAGCTGAGATTACAGGCATGCGCCACCATG
CCTGGCTAATTTTTTTTTTTTGTATTTTTAGTAGAGATGGGGTTTCACCGTGTTGGTCAGGCTGGTCTTGAACTCCTGACCTCAGGTGAT
CCACCCCCCTTGGCCTCCCAAAGAGCTGGGATTACAGGCATGAGCCACTGCGCCTAGCCCCACCCCCCCTACTTTTTTTTTTTTTTTTTT
TTTAATTTTTTGTGTAGCCAAAAGATCTCACTCTGTTGCCCAGACTGCTCTCAAAACTCCTGGCCTTAAGTGATTCCCCTGCCTCAGTCT
CCCAAAGTGCTGGGATTATAGGCATGAGCCACCATGCCTGTCCATTATTTCTTTATAGTGACTATTATATGTAGGCAATGTATAATTGGT
AGAACATAGTCTATGAAACAGTGCGTTAATTGTGGGCAGTGAAGAATCATTGAAGTTGTGAAATTTGTATTTTAACTAGATCATTGTAGT
ATGGCAAAACGGTTAGGAAAGAGAAAGCTATCTTGACTAACTGTTTATGCTATGAGATACTGACTGATGTACATGTACATTTAGTGTTTC
TTTAGGTATACCTGACTTATTCATTGAACACCTATCCACTGATCTCAAAAGTATTCCTCAGGGTAGTCTCCATTCCTGTCATTTTTCCTC
CTATTCATGAGACGGAAAAATTATGACCATGGTACAGAGTTGTATCAAGGAAATGAAGAACTAGAACATTGAATTGAAAGGTTTTGAAAG

>59208_59208_1_NIPBL-NUP155_NIPBL_chr5_37027514_ENST00000282516_NUP155_chr5_37310845_ENST00000231498_length(amino acids)=2533AA_BP=1954
MNGDMPHVPITTLAGIASLTDLLNQLPLPSPLPATTTKSLLFNARIAEEVNCLLACRDDNLVSQLVHSLNQVSTDHIELKDNLGSDDPEG
DIPVLLQAVLARSPNVFREKSMQNRYVQSGMMMSQYKLSQNSMHSSPASSNYQQTTISHSPSSRFVPPQTSSGNRFMPQQNSPVPSPYAP
QSPAGYMPYSHPSSYTTHPQMQQASVSSPIVAGGLRNIHDNKVSGPLSGNSANHHADNPRHGSSEDYLHMVHRLSSDDGDSSTMRNAASF
PLRSPQPVCSPAGSEGTPKGSRPPLILQSQSLPCSSPRDVPPDILLDSPERKQKKQKKMKLGKDEKEQSEKAAMYDIISSPSKDSTKLTL
RLSRVRSSDMDQQEDMISGVENSNVSENDIPFNVQYPGQTSKTPITPQDINRPLNAAQCLSQQEQTAFLPANQVPVLQQNTSVAAKQPQT
SVVQNQQQISQQGPIYDEVELDALAEIERIERESAIERERFSKEVQDKDKPLKKRKQDSYPQEAGGATGGNRPASQETGSTGNGSRPALM
VSIDLHQAGRVDSQASITQDSDSIKKPEEIKQCNDAPVSVLQEDIVGSLKSTPENHPETPKKKSDPELSKSEMKQSESRLAESKPNENRL
VETKSSENKLETKVETQTEELKQNESRTTECKQNESTIVEPKQNENRLSDTKPNDNKQNNGRSETTKSRPETPKQKGESRPETPKQKSDG
HPETPKQKGDGRPETPKQKGESRPETPKQKNEGRPETPKHRHDNRRDSGKPSTEKKPEVSKHKQDTKSDSPRLKSERAEALKQRPDGRSV
SESLRRDHDNKQKSDDRGESERHRGDQSRVRRPETLRSSSRNEHGIKSDSSKTDKLERKHRHESGDSRERPSSGEQKSRPDSPRVKQGDS
NKSRSDKLGFKSPTSKDDKRTEGNKSKVDTNKAHPDNKAEFPSYLLGGRSGALKNFVIPKIKRDKDGNVTQETKKMEMKGEPKDKVEKIG
LVEDLNKGAKPVVVLQKLSLDDVQKLIKDREDKSRSSLKPIKNKPSKSNKGSIDQSVLKELPPELLAEIESTMPLCERVKMNKRKRSTVN
EKPKYAEISSDEDNDSDEAFESSRKRHKKDDDKAWEYEERDRRSSGDHRRSGHSHEGRRSSGGGRYRNRSPSDSDMEDYSPPPSLSEVAR
KMKKKEKQKKRKAYEPKLTPEEMMDSSTFKRFTASIENILDNLEDMDFTAFGDDDEIPQELLLGKHQLNELGSESAKIKAMGIMDKLSTD
KTVKVLNILEKNIQDGSKLSTLLNHNNDTEEEERLWRDLIMERVTKSADACLTTINIMTSPNMPKAVYIEDVIERVIQYTKFHLQNTLYP
QYDPVYRLDPHGGGLLSSKAKRAKCSTHKQRVIVMLYNKVCDIVSSLSELLEIQLLTDTTILQVSSMGITPFFVENVSELQLCAIKLVTA
VFSRYEKHRQLILEEIFTSLARLPTSKRSLRNFRLNSSDMDGEPMYIQMVTALVLQLIQCVVHLPSSEKDSNAEEDSNKKIDQDVVITNS
YETAMRTAQNFLSIFLKKCGSKQGEEDYRPLFENFVQDLLSTVNKPEWPAAELLLSLLGRLLVHQFSNKSTEMALRVASLDYLGTVAARL
RKDAVTSKMDQGSIERILKQVSGGEDEIQQLQKALLDYLDENTETDPSLVFSRKFYIAQWFRDTTLETEKAMKSQKDEESSEGTHHAKEI
ETTGQIMHRAENRKKFLRSIIKTTPSQFSTLKMNSDTVDYDDACLIVRYLASMRPFAQSFDIYLTQILRVLGENAIAVRTKAMKCLSEVV
AVDPSILARLDMQRGVHGRLMDNSTSVREAAVELLGRFVLCRPQLAEQYYDMLIERILDTGISVRKRVIKILRDICIEQPTFPKITEMCV
KMIRRVNDEEGIKKLVNETFQKLWFTPTPHNDKEAMTRKILNITDVVAACRDTGYDWFEQLLQNELQEQLKITTFKDLVIRDKELTGALI
ASLINCYIRDNAAVDGISLHLQDICPLLYSTDDAICSKANELLQRSRQVQNKTEKERMLRESLKEYQKISNQVDLSNVCAQYRQVRFYEG
VVELSLTAAEKKDPQGLGLHFYKHGEPEEDIVGLQAFQERLNSYKCITDTLQELVNQSKAAPQSPSVPKKPGPPVLSSDPNMLSNEEAGH
HFEQMLKLSQRSKDELFSIALYNWLIQVDLADKLLQVASPFLEPHLVRMAKVDQNRVRYMDLLWRYYEKNRSFSNAARVLSRLADMHSTE
ISLQQRLEYIARAILSAKSSTAISSIAADGEFLHELEEKMEVARIQLQIQETLQRQYSHHSSVQDAVSQLDSELMDITKLYGEFADPFKL
AECKLAIIHCAGYSDPILVQTLWQDIIEKELSDSVTLSSSDRMHALSLKIVLLGKIYAGTPRFFPLDFIVQFLEQQVCTLNWDVGFVIQT
MNEIGVPLPRLLEVYDQLFKSRDPFWNRMKKPLHLLDCIHVLLIRYVENPSQVLNCERRRFTNLCLDAVCGYLVELQSMSSSVAVQAITG

--------------------------------------------------------------
>59208_59208_2_NIPBL-NUP155_NIPBL_chr5_37027514_ENST00000282516_NUP155_chr5_37310845_ENST00000381843_length(transcript)=8162nt_BP=6361nt
TCCGGTCGGCATTTTGTTCTGAGAGGGAGAGACGGAACGAGAGAGAGACACACACAGGGCTCCTTCCCCCCGCCCTCCCCCCCCTCCCTC
CGTCGGTACCGACTCACCCGACACCACCAAGCCGCAGGGAGGGACGCCCCCGCCGACAGGAGAATTGGTTCCCGGGCCCGCGGCGATGCC
CCCCCGGTAGCTCGGGCCCGTGGTCGGGTGTTTGTGAGTGTTTCTATGTGGGAGAAGGAGGAGGAGGAGGAAGAAGAAGCAACGATTTGT
CTTCTCGGCTGGTCTCCCCCCGGCTCTACATGTTCCCCGCACTGAGGAGACGGAAGAGGAGCCGTAGCCACCCCCCCTCCCGGCCCGGAT
TATAGTCTCTCGCCACAGCGGCCTCGGCCTCCCCTTGGATTCAGACGCCGATTCGCCCAGTGTTTGGGAAATGGGAAGTAATGACAGCTG
GCACCTGAACTAAGTACTTTTATAGGCAACACCATTCCAGAAATTCAGGATGAATGGGGATATGCCCCATGTCCCCATTACTACTCTTGC
GGGGATTGCTAGTCTCACAGACCTCCTGAACCAGCTGCCTCTTCCATCTCCTTTACCTGCTACAACTACAAAGAGCCTTCTCTTTAATGC
ACGAATAGCAGAAGAGGTGAACTGCCTTTTGGCTTGTAGGGATGACAATTTGGTTTCACAGCTTGTCCATAGCCTCAACCAGGTATCAAC
AGATCACATAGAGTTGAAAGATAACCTTGGCAGTGATGACCCAGAAGGTGACATACCAGTCTTGTTGCAGGCCGTCCTGGCAAGGAGTCC
TAATGTTTTCAGGGAGAAAAGCATGCAGAACAGATATGTACAAAGTGGAATGATGATGTCTCAGTATAAACTTTCTCAGAATTCCATGCA
CAGTAGTCCTGCATCTTCCAATTATCAACAAACCACTATCTCACATAGCCCCTCCAGCCGGTTTGTGCCACCACAGACAAGCTCTGGGAA
CAGATTTATGCCACAGCAAAATAGCCCAGTGCCTAGTCCATACGCCCCACAAAGCCCTGCAGGATACATGCCATATTCCCATCCTTCAAG
TTACACAACACATCCACAGATGCAACAAGCATCGGTATCAAGTCCCATTGTTGCAGGTGGTTTGAGAAACATACATGATAATAAAGTTTC
TGGTCCGTTGTCTGGCAATTCAGCTAATCATCATGCTGATAATCCTAGACATGGTTCAAGTGAGGACTACCTACACATGGTGCACAGGCT
AAGTAGTGACGATGGAGATTCTTCAACAATGAGGAATGCTGCATCTTTTCCCTTGAGATCTCCACAGCCAGTATGCTCCCCTGCTGGAAG
TGAAGGAACTCCTAAAGGCTCAAGACCACCTTTAATCCTACAATCTCAGTCTCTACCTTGTTCATCACCTCGAGATGTTCCACCAGATAT
CTTGCTAGATTCTCCAGAAAGAAAACAAAAGAAGCAGAAGAAAATGAAATTAGGCAAGGATGAAAAAGAGCAGAGTGAGAAAGCGGCAAT
GTATGATATAATTAGTTCTCCATCCAAGGACTCTACTAAACTTACATTAAGACTTTCTCGTGTAAGGTCTTCAGACATGGACCAGCAAGA
GGATATGATTTCTGGTGTGGAAAATAGCAATGTTTCAGAAAATGATATTCCTTTTAATGTGCAGTACCCAGGACAGACTTCAAAAACACC
CATTACTCCACAAGATATAAACCGCCCACTAAATGCTGCTCAATGTTTGTCGCAGCAAGAACAAACAGCATTCCTTCCAGCAAATCAAGT
GCCTGTTTTACAACAGAACACTTCAGTTGCTGCAAAACAACCCCAGACTTCTGTGGTACAGAATCAACAACAGATATCACAACAGGGACC
TATATATGATGAAGTGGAATTGGATGCATTGGCTGAAATTGAGCGAATAGAGAGAGAATCAGCTATTGAAAGGGAGCGCTTCTCAAAAGA
AGTTCAAGATAAAGATAAGCCTTTGAAAAAAAGAAAACAAGATTCTTACCCACAGGAGGCTGGGGGTGCTACAGGAGGTAATAGACCAGC
TTCTCAGGAGACGGGTTCTACGGGAAATGGGTCAAGGCCAGCATTAATGGTTAGCATTGATCTTCATCAGGCAGGAAGAGTGGACTCTCA
GGCTTCTATAACTCAGGATTCAGACTCCATAAAAAAGCCTGAAGAAATCAAACAATGTAATGATGCACCTGTTTCTGTTCTTCAGGAAGA
TATTGTTGGAAGTCTTAAATCTACACCAGAAAACCATCCTGAGACACCTAAAAAAAAGTCTGATCCTGAGCTTTCAAAGAGTGAAATGAA
ACAAAGTGAAAGTAGATTAGCAGAATCTAAACCAAATGAAAACCGATTGGTGGAGACAAAATCAAGTGAAAATAAGTTAGAAACTAAAGT
TGAGACCCAAACAGAAGAACTTAAACAGAATGAGAGCAGAACAACTGAATGCAAACAAAACGAGAGCACCATAGTTGAGCCTAAACAAAA
TGAAAATAGACTGTCTGACACAAAACCAAATGACAACAAACAAAATAATGGCAGATCAGAAACAACAAAATCAAGGCCTGAAACCCCAAA
GCAAAAGGGTGAAAGCCGGCCTGAGACTCCAAAACAAAAGAGTGATGGGCATCCTGAAACCCCAAAACAGAAGGGTGATGGAAGGCCTGA
AACTCCAAAGCAAAAAGGTGAGAGCCGCCCTGAAACTCCAAAGCAAAAAAATGAAGGGCGACCTGAAACACCAAAACACAGGCATGACAA
TAGGAGGGATTCTGGAAAGCCATCTACAGAGAAAAAACCTGAAGTGTCTAAACATAAACAAGATACTAAATCTGACTCACCTCGGTTAAA
ATCAGAACGAGCTGAAGCCTTAAAGCAGAGACCTGATGGGCGATCTGTTTCTGAGTCACTAAGACGTGACCATGATAATAAACAAAAATC
AGATGACAGGGGTGAATCAGAGCGACATCGAGGGGATCAGTCTAGGGTTCGAAGACCAGAAACATTGAGATCCTCTAGTAGAAATGAACA
TGGCATTAAATCTGATAGTTCAAAAACTGATAAACTAGAACGAAAACACAGGCATGAATCAGGGGACTCAAGGGAAAGACCATCTTCTGG
GGAACAAAAATCAAGACCTGACAGTCCTCGTGTTAAACAAGGAGATTCTAATAAATCAAGATCTGATAAACTTGGTTTTAAATCACCAAC
TAGTAAAGATGACAAAAGGACAGAGGGTAACAAGAGTAAAGTAGACACTAATAAAGCACACCCTGACAATAAGGCAGAATTTCCAAGTTA
TTTGTTGGGGGGCAGGTCTGGTGCGTTGAAAAATTTTGTCATTCCGAAAATCAAGAGGGATAAAGATGGCAATGTTACTCAGGAGACAAA
GAAAATGGAAATGAAAGGAGAGCCGAAAGACAAAGTAGAAAAAATAGGATTAGTTGAAGATCTAAATAAAGGAGCTAAGCCTGTAGTTGT
GCTACAAAAACTGTCTTTGGATGATGTTCAGAAACTTATTAAAGATAGAGAGGACAAATCAAGAAGTTCCCTTAAACCTATCAAGAATAA
ACCATCAAAGTCAAATAAAGGTAGTATAGATCAATCAGTGTTAAAAGAATTACCCCCTGAACTCCTGGCAGAAATTGAGTCCACCATGCC
ACTTTGTGAACGTGTGAAAATGAACAAACGCAAGCGTAGCACAGTTAATGAAAAGCCAAAATATGCTGAAATCAGTTCAGATGAAGATAA
TGATAGTGATGAAGCTTTTGAATCCTCTAGGAAACGACATAAAAAAGATGATGATAAAGCTTGGGAATATGAAGAGCGTGACAGAAGAAG
CTCTGGGGATCATAGGAGAAGTGGCCACTCTCATGAAGGAAGAAGGAGTTCAGGTGGTGGTCGTTATCGAAACCGAAGTCCGTCAGATTC
TGACATGGAAGATTATTCTCCTCCTCCCAGCCTTAGTGAGGTTGCTAGGAAAATGAAGAAAAAAGAAAAACAGAAGAAAAGGAAAGCATA
TGAACCAAAACTAACACCTGAAGAAATGATGGACTCTTCAACTTTTAAGAGATTCACAGCCTCAATAGAGAATATTTTGGATAATTTGGA
AGATATGGATTTTACTGCGTTTGGTGATGATGATGAAATTCCTCAGGAACTGCTCTTAGGAAAACATCAGCTTAATGAACTTGGCAGTGA
ATCTGCTAAAATAAAAGCAATGGGTATAATGGATAAGCTTTCAACTGACAAAACTGTGAAAGTCTTAAATATCTTGGAGAAGAATATTCA
GGATGGGTCAAAGCTTTCCACTTTGTTAAATCATAATAACGATACTGAAGAAGAAGAAAGGTTATGGAGAGACCTTATTATGGAGAGAGT
TACAAAATCAGCGGATGCTTGTCTTACAACTATCAACATTATGACATCCCCTAACATGCCAAAAGCTGTGTACATTGAGGATGTAATTGA
AAGAGTTATACAGTACACTAAATTTCATTTGCAGAATACACTTTATCCTCAGTATGATCCTGTTTACAGATTAGATCCTCATGGAGGAGG
CTTATTAAGTTCAAAAGCAAAACGGGCTAAATGTTCTACCCATAAGCAGAGAGTAATAGTAATGCTTTATAACAAAGTTTGTGACATTGT
TAGCAGCTTATCAGAATTGCTAGAGATACAACTTCTTACAGACACAACAATTCTTCAGGTTTCATCTATGGGAATAACACCATTTTTTGT
GGAAAATGTCAGTGAACTACAGTTGTGTGCCATTAAGTTAGTCACTGCAGTATTCTCAAGATATGAAAAACATAGGCAGTTAATTTTGGA
AGAAATTTTTACTTCACTTGCAAGATTACCAACCAGCAAGAGGAGTTTAAGGAACTTCAGGTTAAACAGTAGTGATATGGATGGAGAACC
TATGTATATTCAGATGGTTACAGCACTGGTTTTACAACTTATTCAGTGTGTGGTACACTTACCATCATCAGAGAAGGACTCTAATGCAGA
AGAAGATTCAAATAAAAAAATTGACCAGGATGTTGTCATTACTAACTCTTATGAAACAGCTATGCGAACAGCCCAAAACTTCCTCTCCAT
CTTCCTTAAAAAATGTGGTAGTAAGCAAGGTGAAGAAGATTACAGACCACTGTTTGAAAATTTTGTTCAAGACCTTCTTTCAACAGTCAA
TAAGCCTGAATGGCCAGCTGCTGAACTACTCCTTAGTTTGTTAGGGAGACTGTTGGTTCATCAGTTCAGTAACAAGTCAACAGAGATGGC
TTTAAGAGTGGCATCTCTTGATTACCTTGGAACTGTTGCTGCACGGCTAAGAAAAGATGCTGTTACAAGCAAAATGGATCAAGGATCTAT
AGAACGCATTTTAAAACAGGTTTCAGGAGGGGAAGATGAAATCCAACAATTACAAAAAGCATTGCTTGATTACTTGGATGAAAACACTGA
GACTGATCCTTCACTAGTGTTTTCTCGTAAATTCTATATAGCCCAGTGGTTTCGAGACACAACTCTGGAAACAGAAAAAGCAATGAAATC
ACAAAAAGATGAAGAATCATCTGAAGGAACACATCATGCAAAGGAAATTGAGACAACTGGCCAAATTATGCATCGAGCTGAAAACCGAAA
AAAGTTTCTTAGAAGCATTATCAAAACCACACCTTCTCAGTTTAGCACATTAAAGATGAACTCTGATACTGTGGACTATGATGATGCTTG
CTTGATTGTTCGATACTTGGCCTCCATGAGGCCGTTTGCCCAGAGCTTTGATATTTATTTGACACAGATCCTACGAGTTCTTGGTGAAAA
TGCAATTGCTGTTCGAACAAAAGCCATGAAGTGTTTGTCTGAGGTTGTTGCTGTAGACCCCAGTATTCTAGCAAGGCTTGATATGCAACG
AGGTGTTCATGGACGATTGATGGATAATTCGACTAGTGTCCGAGAAGCAGCAGTAGAATTACTAGGTCGATTTGTCCTTTGTCGACCTCA
GCTTGCTGAACAGTATTATGATATGCTGATTGAAAGAATATTGGATACTGGTATCAGTGTCAGGAAAAGAGTAATAAAGATTCTCAGAGA
CATTTGTATTGAACAACCAACATTTCCAAAAATCACAGAAATGTGTGTAAAAATGATTCGCAGAGTCAATGATGAAGAGGGCATTAAGAA
ATTAGTAAATGAAACATTCCAGAAACTCTGGTTTACTCCAACTCCACACAATGACAAAGAAGCAATGACAAGGAAAATTTTAAACATTAC
CGATGTGGTTGCAGCATGCAGAGATACTGGATATGACTGGTTTGAGCAACTGCTTCAAAACGAACTTCAAGAGCAGCTGAAGATCACCAC
CTTTAAAGATCTTGTAATCAGGGACAAAGAACTCACAGGGGCATTAATTGCTTCTCTTATCAACTGCTACATCAGAGATAATGCCGCTGT
TGATGGCATTAGTTTACATTTACAGGATATCTGCCCACTTCTATATAGCACTGATGATGCAATTTGTTCTAAGGCAAATGAGCTTCTCCA
GCGTTCCCGACAAGTTCAAAATAAGACTGAAAAAGAAAGAATGTTAAGGGAATCATTAAAGGAATATCAAAAAATTAGCAATCAAGTGGA
CCTTTCCAATGTTTGTGCTCAGTATAGACAAGTGAGATTTTATGAGGGTGTGGTGGAACTTTCTCTTACGGCTGCAGAGAAAAAAGATCC
TCAAGGTCTTGGGCTTCATTTCTATAAACATGGAGAACCAGAAGAAGACATAGTTGGACTTCAGGCCTTCCAAGAAAGATTAAACAGTTA
CAAATGCATTACAGACACACTTCAAGAACTGGTAAATCAAAGTAAGGCCGCTCCTCAGTCTCCCAGTGTACCCAAAAAACCTGGTCCTCC
AGTGTTGTCATCTGATCCAAATATGCTGAGTAATGAAGAAGCAGGACATCATTTTGAACAAATGCTTAAATTGTCACAGCGATCCAAGGA
TGAGCTCTTTAGTATTGCCCTTTATAATTGGCTAATACAAGTCGACCTTGCAGATAAGCTGCTACAGGTTGCTTCTCCATTTCTGGAGCC
ACATCTAGTCCGAATGGCCAAAGTTGATCAAAACAGAGTTCGTTATATGGATTTACTCTGGCGGTATTACGAGAAGAACAGAAGTTTCAG
TAATGCTGCTCGTGTACTGTCCAGACTGGCTGACATGCATAGCACAGAAATTTCACTTCAGCAGCGACTAGAGTACATTGCTCGAGCCAT
TCTTAGTGCCAAAAGTTCCACTGCCATTTCATCAATAGCTGCCGATGGTGAATTTCTTCATGAATTAGAAGAAAAAATGGAGGTTGCTAG
GATCCAACTTCAGATACAGGAGACACTACAAAGGCAGTATTCCCATCATTCTTCTGTACAGGATGCAGTTTCTCAGCTGGATTCTGAGCT
GATGGACATAACTAAGCTTTATGGGGAATTTGCTGACCCATTTAAACTTGCAGAGTGCAAACTTGCAATAATTCATTGTGCCGGTTATTC
AGACCCTATATTGGTGCAGACACTTTGGCAAGATATCATAGAGAAAGAATTGAGTGACAGTGTGACATTGAGCTCCTCGGATAGAATGCA
TGCTCTTAGTCTCAAGATTGTTCTCCTTGGCAAAATTTATGCTGGCACACCACGCTTCTTTCCTTTAGATTTTATTGTACAGTTTTTAGA
ACAGCAGGTTTGTACTTTGAACTGGGATGTGGGCTTCGTAATACAGACAATGAATGAAATTGGAGTACCATTACCTAGACTACTAGAAGT
TTATGATCAGTTGTTCAAATCACGGGATCCATTCTGGAACAGAATGAAGAAGCCACTGCACCTTTTGGATTGTATACATGTATTATTGAT
AAGATATGTTGAGAATCCCAGCCAAGTTTTAAATTGTGAAAGGAGAAGATTTACAAATCTCTGCCTGGATGCTGTTTGTGGTTACCTTGT
TGAGCTCCAGTCTATGAGCTCGTCAGTAGCAGTACAAGCCATCACTGGGAATTTTAAATCTCTTCAAGCTAAATTAGAACGGCTTCATTA

>59208_59208_2_NIPBL-NUP155_NIPBL_chr5_37027514_ENST00000282516_NUP155_chr5_37310845_ENST00000381843_length(amino acids)=2533AA_BP=1954
MNGDMPHVPITTLAGIASLTDLLNQLPLPSPLPATTTKSLLFNARIAEEVNCLLACRDDNLVSQLVHSLNQVSTDHIELKDNLGSDDPEG
DIPVLLQAVLARSPNVFREKSMQNRYVQSGMMMSQYKLSQNSMHSSPASSNYQQTTISHSPSSRFVPPQTSSGNRFMPQQNSPVPSPYAP
QSPAGYMPYSHPSSYTTHPQMQQASVSSPIVAGGLRNIHDNKVSGPLSGNSANHHADNPRHGSSEDYLHMVHRLSSDDGDSSTMRNAASF
PLRSPQPVCSPAGSEGTPKGSRPPLILQSQSLPCSSPRDVPPDILLDSPERKQKKQKKMKLGKDEKEQSEKAAMYDIISSPSKDSTKLTL
RLSRVRSSDMDQQEDMISGVENSNVSENDIPFNVQYPGQTSKTPITPQDINRPLNAAQCLSQQEQTAFLPANQVPVLQQNTSVAAKQPQT
SVVQNQQQISQQGPIYDEVELDALAEIERIERESAIERERFSKEVQDKDKPLKKRKQDSYPQEAGGATGGNRPASQETGSTGNGSRPALM
VSIDLHQAGRVDSQASITQDSDSIKKPEEIKQCNDAPVSVLQEDIVGSLKSTPENHPETPKKKSDPELSKSEMKQSESRLAESKPNENRL
VETKSSENKLETKVETQTEELKQNESRTTECKQNESTIVEPKQNENRLSDTKPNDNKQNNGRSETTKSRPETPKQKGESRPETPKQKSDG
HPETPKQKGDGRPETPKQKGESRPETPKQKNEGRPETPKHRHDNRRDSGKPSTEKKPEVSKHKQDTKSDSPRLKSERAEALKQRPDGRSV
SESLRRDHDNKQKSDDRGESERHRGDQSRVRRPETLRSSSRNEHGIKSDSSKTDKLERKHRHESGDSRERPSSGEQKSRPDSPRVKQGDS
NKSRSDKLGFKSPTSKDDKRTEGNKSKVDTNKAHPDNKAEFPSYLLGGRSGALKNFVIPKIKRDKDGNVTQETKKMEMKGEPKDKVEKIG
LVEDLNKGAKPVVVLQKLSLDDVQKLIKDREDKSRSSLKPIKNKPSKSNKGSIDQSVLKELPPELLAEIESTMPLCERVKMNKRKRSTVN
EKPKYAEISSDEDNDSDEAFESSRKRHKKDDDKAWEYEERDRRSSGDHRRSGHSHEGRRSSGGGRYRNRSPSDSDMEDYSPPPSLSEVAR
KMKKKEKQKKRKAYEPKLTPEEMMDSSTFKRFTASIENILDNLEDMDFTAFGDDDEIPQELLLGKHQLNELGSESAKIKAMGIMDKLSTD
KTVKVLNILEKNIQDGSKLSTLLNHNNDTEEEERLWRDLIMERVTKSADACLTTINIMTSPNMPKAVYIEDVIERVIQYTKFHLQNTLYP
QYDPVYRLDPHGGGLLSSKAKRAKCSTHKQRVIVMLYNKVCDIVSSLSELLEIQLLTDTTILQVSSMGITPFFVENVSELQLCAIKLVTA
VFSRYEKHRQLILEEIFTSLARLPTSKRSLRNFRLNSSDMDGEPMYIQMVTALVLQLIQCVVHLPSSEKDSNAEEDSNKKIDQDVVITNS
YETAMRTAQNFLSIFLKKCGSKQGEEDYRPLFENFVQDLLSTVNKPEWPAAELLLSLLGRLLVHQFSNKSTEMALRVASLDYLGTVAARL
RKDAVTSKMDQGSIERILKQVSGGEDEIQQLQKALLDYLDENTETDPSLVFSRKFYIAQWFRDTTLETEKAMKSQKDEESSEGTHHAKEI
ETTGQIMHRAENRKKFLRSIIKTTPSQFSTLKMNSDTVDYDDACLIVRYLASMRPFAQSFDIYLTQILRVLGENAIAVRTKAMKCLSEVV
AVDPSILARLDMQRGVHGRLMDNSTSVREAAVELLGRFVLCRPQLAEQYYDMLIERILDTGISVRKRVIKILRDICIEQPTFPKITEMCV
KMIRRVNDEEGIKKLVNETFQKLWFTPTPHNDKEAMTRKILNITDVVAACRDTGYDWFEQLLQNELQEQLKITTFKDLVIRDKELTGALI
ASLINCYIRDNAAVDGISLHLQDICPLLYSTDDAICSKANELLQRSRQVQNKTEKERMLRESLKEYQKISNQVDLSNVCAQYRQVRFYEG
VVELSLTAAEKKDPQGLGLHFYKHGEPEEDIVGLQAFQERLNSYKCITDTLQELVNQSKAAPQSPSVPKKPGPPVLSSDPNMLSNEEAGH
HFEQMLKLSQRSKDELFSIALYNWLIQVDLADKLLQVASPFLEPHLVRMAKVDQNRVRYMDLLWRYYEKNRSFSNAARVLSRLADMHSTE
ISLQQRLEYIARAILSAKSSTAISSIAADGEFLHELEEKMEVARIQLQIQETLQRQYSHHSSVQDAVSQLDSELMDITKLYGEFADPFKL
AECKLAIIHCAGYSDPILVQTLWQDIIEKELSDSVTLSSSDRMHALSLKIVLLGKIYAGTPRFFPLDFIVQFLEQQVCTLNWDVGFVIQT
MNEIGVPLPRLLEVYDQLFKSRDPFWNRMKKPLHLLDCIHVLLIRYVENPSQVLNCERRRFTNLCLDAVCGYLVELQSMSSSVAVQAITG

--------------------------------------------------------------
>59208_59208_3_NIPBL-NUP155_NIPBL_chr5_37027514_ENST00000448238_NUP155_chr5_37310845_ENST00000231498_length(transcript)=11833nt_BP=6330nt
ACGGAACGAGAGAGAGACACACACAGGGCTCCTTCCCCCCGCCCTCCCCCCCCTCCCTCCGTCGGTACCGACTCACCCGACACCACCAAG
CCGCAGGGAGGGACGCCCCCGCCGACAGGAGAATTGGTTCCCGGGCCCGCGGCGATGCCCCCCCGGTAGCTCGGGCCCGTGGTCGGGTGT
TTGTGAGTGTTTCTATGTGGGAGAAGGAGGAGGAGGAGGAAGAAGAAGCAACGATTTGTCTTCTCGGCTGGTCTCCCCCCGGCTCTACAT
GTTCCCCGCACTGAGGAGACGGAAGAGGAGCCGTAGCCACCCCCCCTCCCGGCCCGGATTATAGTCTCTCGCCACAGCGGCCTCGGCCTC
CCCTTGGATTCAGACGCCGATTCGCCCAGTGTTTGGGAAATGGGAAGTAATGACAGCTGGCACCTGAACTAAGTACTTTTATAGGCAACA
CCATTCCAGAAATTCAGGATGAATGGGGATATGCCCCATGTCCCCATTACTACTCTTGCGGGGATTGCTAGTCTCACAGACCTCCTGAAC
CAGCTGCCTCTTCCATCTCCTTTACCTGCTACAACTACAAAGAGCCTTCTCTTTAATGCACGAATAGCAGAAGAGGTGAACTGCCTTTTG
GCTTGTAGGGATGACAATTTGGTTTCACAGCTTGTCCATAGCCTCAACCAGGTATCAACAGATCACATAGAGTTGAAAGATAACCTTGGC
AGTGATGACCCAGAAGGTGACATACCAGTCTTGTTGCAGGCCGTCCTGGCAAGGAGTCCTAATGTTTTCAGGGAGAAAAGCATGCAGAAC
AGATATGTACAAAGTGGAATGATGATGTCTCAGTATAAACTTTCTCAGAATTCCATGCACAGTAGTCCTGCATCTTCCAATTATCAACAA
ACCACTATCTCACATAGCCCCTCCAGCCGGTTTGTGCCACCACAGACAAGCTCTGGGAACAGATTTATGCCACAGCAAAATAGCCCAGTG
CCTAGTCCATACGCCCCACAAAGCCCTGCAGGATACATGCCATATTCCCATCCTTCAAGTTACACAACACATCCACAGATGCAACAAGCA
TCGGTATCAAGTCCCATTGTTGCAGGTGGTTTGAGAAACATACATGATAATAAAGTTTCTGGTCCGTTGTCTGGCAATTCAGCTAATCAT
CATGCTGATAATCCTAGACATGGTTCAAGTGAGGACTACCTACACATGGTGCACAGGCTAAGTAGTGACGATGGAGATTCTTCAACAATG
AGGAATGCTGCATCTTTTCCCTTGAGATCTCCACAGCCAGTATGCTCCCCTGCTGGAAGTGAAGGAACTCCTAAAGGCTCAAGACCACCT
TTAATCCTACAATCTCAGTCTCTACCTTGTTCATCACCTCGAGATGTTCCACCAGATATCTTGCTAGATTCTCCAGAAAGAAAACAAAAG
AAGCAGAAGAAAATGAAATTAGGCAAGGATGAAAAAGAGCAGAGTGAGAAAGCGGCAATGTATGATATAATTAGTTCTCCATCCAAGGAC
TCTACTAAACTTACATTAAGACTTTCTCGTGTAAGGTCTTCAGACATGGACCAGCAAGAGGATATGATTTCTGGTGTGGAAAATAGCAAT
GTTTCAGAAAATGATATTCCTTTTAATGTGCAGTACCCAGGACAGACTTCAAAAACACCCATTACTCCACAAGATATAAACCGCCCACTA
AATGCTGCTCAATGTTTGTCGCAGCAAGAACAAACAGCATTCCTTCCAGCAAATCAAGTGCCTGTTTTACAACAGAACACTTCAGTTGCT
GCAAAACAACCCCAGACTTCTGTGGTACAGAATCAACAACAGATATCACAACAGGGACCTATATATGATGAAGTGGAATTGGATGCATTG
GCTGAAATTGAGCGAATAGAGAGAGAATCAGCTATTGAAAGGGAGCGCTTCTCAAAAGAAGTTCAAGATAAAGATAAGCCTTTGAAAAAA
AGAAAACAAGATTCTTACCCACAGGAGGCTGGGGGTGCTACAGGAGGTAATAGACCAGCTTCTCAGGAGACGGGTTCTACGGGAAATGGG
TCAAGGCCAGCATTAATGGTTAGCATTGATCTTCATCAGGCAGGAAGAGTGGACTCTCAGGCTTCTATAACTCAGGATTCAGACTCCATA
AAAAAGCCTGAAGAAATCAAACAATGTAATGATGCACCTGTTTCTGTTCTTCAGGAAGATATTGTTGGAAGTCTTAAATCTACACCAGAA
AACCATCCTGAGACACCTAAAAAAAAGTCTGATCCTGAGCTTTCAAAGAGTGAAATGAAACAAAGTGAAAGTAGATTAGCAGAATCTAAA
CCAAATGAAAACCGATTGGTGGAGACAAAATCAAGTGAAAATAAGTTAGAAACTAAAGTTGAGACCCAAACAGAAGAACTTAAACAGAAT
GAGAGCAGAACAACTGAATGCAAACAAAACGAGAGCACCATAGTTGAGCCTAAACAAAATGAAAATAGACTGTCTGACACAAAACCAAAT
GACAACAAACAAAATAATGGCAGATCAGAAACAACAAAATCAAGGCCTGAAACCCCAAAGCAAAAGGGTGAAAGCCGGCCTGAGACTCCA
AAACAAAAGAGTGATGGGCATCCTGAAACCCCAAAACAGAAGGGTGATGGAAGGCCTGAAACTCCAAAGCAAAAAGGTGAGAGCCGCCCT
GAAACTCCAAAGCAAAAAAATGAAGGGCGACCTGAAACACCAAAACACAGGCATGACAATAGGAGGGATTCTGGAAAGCCATCTACAGAG
AAAAAACCTGAAGTGTCTAAACATAAACAAGATACTAAATCTGACTCACCTCGGTTAAAATCAGAACGAGCTGAAGCCTTAAAGCAGAGA
CCTGATGGGCGATCTGTTTCTGAGTCACTAAGACGTGACCATGATAATAAACAAAAATCAGATGACAGGGGTGAATCAGAGCGACATCGA
GGGGATCAGTCTAGGGTTCGAAGACCAGAAACATTGAGATCCTCTAGTAGAAATGAACATGGCATTAAATCTGATAGTTCAAAAACTGAT
AAACTAGAACGAAAACACAGGCATGAATCAGGGGACTCAAGGGAAAGACCATCTTCTGGGGAACAAAAATCAAGACCTGACAGTCCTCGT
GTTAAACAAGGAGATTCTAATAAATCAAGATCTGATAAACTTGGTTTTAAATCACCAACTAGTAAAGATGACAAAAGGACAGAGGGTAAC
AAGAGTAAAGTAGACACTAATAAAGCACACCCTGACAATAAGGCAGAATTTCCAAGTTATTTGTTGGGGGGCAGGTCTGGTGCGTTGAAA
AATTTTGTCATTCCGAAAATCAAGAGGGATAAAGATGGCAATGTTACTCAGGAGACAAAGAAAATGGAAATGAAAGGAGAGCCGAAAGAC
AAAGTAGAAAAAATAGGATTAGTTGAAGATCTAAATAAAGGAGCTAAGCCTGTAGTTGTGCTACAAAAACTGTCTTTGGATGATGTTCAG
AAACTTATTAAAGATAGAGAGGACAAATCAAGAAGTTCCCTTAAACCTATCAAGAATAAACCATCAAAGTCAAATAAAGGTAGTATAGAT
CAATCAGTGTTAAAAGAATTACCCCCTGAACTCCTGGCAGAAATTGAGTCCACCATGCCACTTTGTGAACGTGTGAAAATGAACAAACGC
AAGCGTAGCACAGTTAATGAAAAGCCAAAATATGCTGAAATCAGTTCAGATGAAGATAATGATAGTGATGAAGCTTTTGAATCCTCTAGG
AAACGACATAAAAAAGATGATGATAAAGCTTGGGAATATGAAGAGCGTGACAGAAGAAGCTCTGGGGATCATAGGAGAAGTGGCCACTCT
CATGAAGGAAGAAGGAGTTCAGGTGGTGGTCGTTATCGAAACCGAAGTCCGTCAGATTCTGACATGGAAGATTATTCTCCTCCTCCCAGC
CTTAGTGAGGTTGCTAGGAAAATGAAGAAAAAAGAAAAACAGAAGAAAAGGAAAGCATATGAACCAAAACTAACACCTGAAGAAATGATG
GACTCTTCAACTTTTAAGAGATTCACAGCCTCAATAGAGAATATTTTGGATAATTTGGAAGATATGGATTTTACTGCGTTTGGTGATGAT
GATGAAATTCCTCAGGAACTGCTCTTAGGAAAACATCAGCTTAATGAACTTGGCAGTGAATCTGCTAAAATAAAAGCAATGGGTATAATG
GATAAGCTTTCAACTGACAAAACTGTGAAAGTCTTAAATATCTTGGAGAAGAATATTCAGGATGGGTCAAAGCTTTCCACTTTGTTAAAT
CATAATAACGATACTGAAGAAGAAGAAAGGTTATGGAGAGACCTTATTATGGAGAGAGTTACAAAATCAGCGGATGCTTGTCTTACAACT
ATCAACATTATGACATCCCCTAACATGCCAAAAGCTGTGTACATTGAGGATGTAATTGAAAGAGTTATACAGTACACTAAATTTCATTTG
CAGAATACACTTTATCCTCAGTATGATCCTGTTTACAGATTAGATCCTCATGGAGGAGGCTTATTAAGTTCAAAAGCAAAACGGGCTAAA
TGTTCTACCCATAAGCAGAGAGTAATAGTAATGCTTTATAACAAAGTTTGTGACATTGTTAGCAGCTTATCAGAATTGCTAGAGATACAA
CTTCTTACAGACACAACAATTCTTCAGGTTTCATCTATGGGAATAACACCATTTTTTGTGGAAAATGTCAGTGAACTACAGTTGTGTGCC
ATTAAGTTAGTCACTGCAGTATTCTCAAGATATGAAAAACATAGGCAGTTAATTTTGGAAGAAATTTTTACTTCACTTGCAAGATTACCA
ACCAGCAAGAGGAGTTTAAGGAACTTCAGGTTAAACAGTAGTGATATGGATGGAGAACCTATGTATATTCAGATGGTTACAGCACTGGTT
TTACAACTTATTCAGTGTGTGGTACACTTACCATCATCAGAGAAGGACTCTAATGCAGAAGAAGATTCAAATAAAAAAATTGACCAGGAT
GTTGTCATTACTAACTCTTATGAAACAGCTATGCGAACAGCCCAAAACTTCCTCTCCATCTTCCTTAAAAAATGTGGTAGTAAGCAAGGT
GAAGAAGATTACAGACCACTGTTTGAAAATTTTGTTCAAGACCTTCTTTCAACAGTCAATAAGCCTGAATGGCCAGCTGCTGAACTACTC
CTTAGTTTGTTAGGGAGACTGTTGGTTCATCAGTTCAGTAACAAGTCAACAGAGATGGCTTTAAGAGTGGCATCTCTTGATTACCTTGGA
ACTGTTGCTGCACGGCTAAGAAAAGATGCTGTTACAAGCAAAATGGATCAAGGATCTATAGAACGCATTTTAAAACAGGTTTCAGGAGGG
GAAGATGAAATCCAACAATTACAAAAAGCATTGCTTGATTACTTGGATGAAAACACTGAGACTGATCCTTCACTAGTGTTTTCTCGTAAA
TTCTATATAGCCCAGTGGTTTCGAGACACAACTCTGGAAACAGAAAAAGCAATGAAATCACAAAAAGATGAAGAATCATCTGAAGGAACA
CATCATGCAAAGGAAATTGAGACAACTGGCCAAATTATGCATCGAGCTGAAAACCGAAAAAAGTTTCTTAGAAGCATTATCAAAACCACA
CCTTCTCAGTTTAGCACATTAAAGATGAACTCTGATACTGTGGACTATGATGATGCTTGCTTGATTGTTCGATACTTGGCCTCCATGAGG
CCGTTTGCCCAGAGCTTTGATATTTATTTGACACAGATCCTACGAGTTCTTGGTGAAAATGCAATTGCTGTTCGAACAAAAGCCATGAAG
TGTTTGTCTGAGGTTGTTGCTGTAGACCCCAGTATTCTAGCAAGGCTTGATATGCAACGAGGTGTTCATGGACGATTGATGGATAATTCG
ACTAGTGTCCGAGAAGCAGCAGTAGAATTACTAGGTCGATTTGTCCTTTGTCGACCTCAGCTTGCTGAACAGTATTATGATATGCTGATT
GAAAGAATATTGGATACTGGTATCAGTGTCAGGAAAAGAGTAATAAAGATTCTCAGAGACATTTGTATTGAACAACCAACATTTCCAAAA
ATCACAGAAATGTGTGTAAAAATGATTCGCAGAGTCAATGATGAAGAGGGCATTAAGAAATTAGTAAATGAAACATTCCAGAAACTCTGG
TTTACTCCAACTCCACACAATGACAAAGAAGCAATGACAAGGAAAATTTTAAACATTACCGATGTGGTTGCAGCATGCAGAGATACTGGA
TATGACTGGTTTGAGCAACTGCTTCAAAACGAACTTCAAGAGCAGCTGAAGATCACCACCTTTAAAGATCTTGTAATCAGGGACAAAGAA
CTCACAGGGGCATTAATTGCTTCTCTTATCAACTGCTACATCAGAGATAATGCCGCTGTTGATGGCATTAGTTTACATTTACAGGATATC
TGCCCACTTCTATATAGCACTGATGATGCAATTTGTTCTAAGGCAAATGAGCTTCTCCAGCGTTCCCGACAAGTTCAAAATAAGACTGAA
AAAGAAAGAATGTTAAGGGAATCATTAAAGGAATATCAAAAAATTAGCAATCAAGTGGACCTTTCCAATGTTTGTGCTCAGTATAGACAA
GTGAGATTTTATGAGGGTGTGGTGGAACTTTCTCTTACGGCTGCAGAGAAAAAAGATCCTCAAGGTCTTGGGCTTCATTTCTATAAACAT
GGAGAACCAGAAGAAGACATAGTTGGACTTCAGGCCTTCCAAGAAAGATTAAACAGTTACAAATGCATTACAGACACACTTCAAGAACTG
GTAAATCAAAGTAAGGCCGCTCCTCAGTCTCCCAGTGTACCCAAAAAACCTGGTCCTCCAGTGTTGTCATCTGATCCAAATATGCTGAGT
AATGAAGAAGCAGGACATCATTTTGAACAAATGCTTAAATTGTCACAGCGATCCAAGGATGAGCTCTTTAGTATTGCCCTTTATAATTGG
CTAATACAAGTCGACCTTGCAGATAAGCTGCTACAGGTTGCTTCTCCATTTCTGGAGCCACATCTAGTCCGAATGGCCAAAGTTGATCAA
AACAGAGTTCGTTATATGGATTTACTCTGGCGGTATTACGAGAAGAACAGAAGTTTCAGTAATGCTGCTCGTGTACTGTCCAGACTGGCT
GACATGCATAGCACAGAAATTTCACTTCAGCAGCGACTAGAGTACATTGCTCGAGCCATTCTTAGTGCCAAAAGTTCCACTGCCATTTCA
TCAATAGCTGCCGATGGTGAATTTCTTCATGAATTAGAAGAAAAAATGGAGGTTGCTAGGATCCAACTTCAGATACAGGAGACACTACAA
AGGCAGTATTCCCATCATTCTTCTGTACAGGATGCAGTTTCTCAGCTGGATTCTGAGCTGATGGACATAACTAAGCTTTATGGGGAATTT
GCTGACCCATTTAAACTTGCAGAGTGCAAACTTGCAATAATTCATTGTGCCGGTTATTCAGACCCTATATTGGTGCAGACACTTTGGCAA
GATATCATAGAGAAAGAATTGAGTGACAGTGTGACATTGAGCTCCTCGGATAGAATGCATGCTCTTAGTCTCAAGATTGTTCTCCTTGGC
AAAATTTATGCTGGCACACCACGCTTCTTTCCTTTAGATTTTATTGTACAGTTTTTAGAACAGCAGGTTTGTACTTTGAACTGGGATGTG
GGCTTCGTAATACAGACAATGAATGAAATTGGAGTACCATTACCTAGACTACTAGAAGTTTATGATCAGTTGTTCAAATCACGGGATCCA
TTCTGGAACAGAATGAAGAAGCCACTGCACCTTTTGGATTGTATACATGTATTATTGATAAGATATGTTGAGAATCCCAGCCAAGTTTTA
AATTGTGAAAGGAGAAGATTTACAAATCTCTGCCTGGATGCTGTTTGTGGTTACCTTGTTGAGCTCCAGTCTATGAGCTCGTCAGTAGCA
GTACAAGCCATCACTGGGAATTTTAAATCTCTTCAAGCTAAATTAGAACGGCTTCATTAATTACTGTGATATACTTTCATCCGTTTTATG
ATCTGTAAAATAAAAACTCAGCTGGGTCCAGATATCAGGTGTTCTAAATCTAAGAATGTAAGAACAATCTTAATAGAAATATGTTTTTAA
TAAGTGGCTAATATCTACAAATAGTACCTTTGCTAAATGAATTCTTTTTTATGACTATTTTGTTTTTTAGTAATTGGGTGAAAAAACAAC
TGAAATGAGATTATTTATTATTTTAACATAAGGATTAAAAAAATTTAGAAACTCTTATTTTGAATTGTACTGCAGGCAGAAATTTCGAAT
TTATATTATTCATTTTCAAGTTAGTCCAAGGATATTGGCATTAAAACTCCACTAGGCGGCCAGGCACAGTGACTTACACCTGTAATCCCA
GCACTTTGGGAGGCCAAGGTGGGCGAATCACGAGGCCAAGAGTTTGAGACCAACCTGGCCAACATGGTGAAACCCCATCTCTACTAAAAA
TACAAAAAAAAATAGCCAGGCGTGGTGGCGGGCGCCTGTAATCCCAGCTACTCGGGAGGCTGAGGGAGGCGAATCACTTGAACCCGGGAG
GCAGAGGTTTCAGTGAGTCAAAATCGCACCATTGCACTCCAGCCCAGGCAACAGGGCGAGACTCTGTCTCAAAAAACAAAAAAACCTCAA
ATAGGCTAAGCAGATCCATTCCCATAATAGTGGATTCTAAAACCGTCCTTAAATAGGCAAATAACTGACTTTTTCAAAACTTTTTTTAGG
TGTTGGGTTCACCCTTGAAAGAACTGTCCTCTAACAACTGGTTTTGTCAGTTAAAGCCCTTGAGAATTGACATAGCTATATACCTGGTTG
AGCAGGTGATAAAACTTGTAACTAATGTTGTGTCCTGAAAACCTACACAGGGAGGTACTGTTTTCCCTTAGTGTCTACCTGGCTGCTTGG
CCTTGTGACTACTGATTCCATTAGAGCAGTGGTTCTCAAAGTATGTGCTCCAAACCAGAAGCATCAGCATCAGCATCAGCATCACCTAGG
AATTTGTTAGAAATGCAAATTCTCGAGCCCCAACCCAGACCTACTGAATCAAAAACGTGGGGGATGAGGCCCTGCTTTCTATGTTTTAAC
AAGCTCTCCAGGAGATTTTGGTGCATGTCAAATTTGAAAGCCACTGCAGTAAAGGATACTGCTACCTTCCATAGTTTATGGACTGAGCTA
CCTATCTGGCTCCTCCTCTGTGAATAACCACACACACAAATTTTGCCCAAGGCACACAATATATAAAGCAAAACTGTTAGTAATGTACTT
TTTAATTATTCCTTAACAAAATAGAATAACCAAACCAAATGCTTCAAAGTAATAGCAACAAGAGAGAAGAAGAGTGGGAATGACCAGAGC
TAACAAAACACTCTATTCCTTTCTCTCTTTTTTTTTTTTTTGGAGACAGAATCTCACCCTGTAGCCCAGCCTGGAGTGCAGTGGTGCGAT
CCCGGCTCACTGCAACCTCTGCCTCACAGGTTTGAAGCAATTTGCCTGCCTCAGCCTCTCGAGTAGCTGGGATTGCAGGTGTGCGCCACC
ATACCCAGCTAATTTTTGTATTTTTAGTAGAGATGGGTTTCACCATGTTGGCCAGGCTGGTCTTGAACTCCTGACCTCAAGTGATCTGCC
CGCCTCCACCTCCCAAAGTGTTGAGATTACAGACGTGAGCCAATGTGCCTGGCCTATTCCCTTCTCTCTTTATGCTACCACAAATAATTA
CCTTCTGTTTATTGTAAGTGATGCATGTCTAACAATTTGTACAATACATTTTGAATATATTTTTCCTTCCATTATTGTCTTTTCCCAAGA
CCATAGGGTTGCCTTCTCTACATTTGTTCTCTTAGAATTCAGCTCCCTTTTCCCTATAATCTTCTAATGTAGAATATTTAATAGAATGCC
AGAACGTCACTCAGTGGGTACTACTACCTCTTATTTTTCAACTTTTCAGTTTCTTAAGTTTAGCGTTTTTTGAATATGTAAAGTGAATGT
ATGCGATACATTAATTCGTTTTATAAATTTAAAATTCTGTCATGTCTACTTAAAAGGAAGGCCTTGTCTGAATGTTGTAATTTAGGTGTG
ACTCCAGTTCTGCTAGAGATAAGAACTTCATTTTTGTTTTAAGCACATTTACATACTAGCAATATGTTGTTATATATACTCAGCTCACAA
CATTGAAAGTACATGTTTTAAAAGGGCTGTAGGCTTCCATGGTTAGATGGTCTGTTAGAGTCAGAAATCTGAACACTGTCCTTTTATTCA
CACAGCATGCTTTGAGAGGTTTTAGGAATTCCAGCCCCACAACAGATGCTTGCAATACCTTTTGGGGGGTAAGATTCCTAAGAGAGAAGA
AATTAGGTCCCCTCATTTTTACCCTTGGAACAGTGTTTCTAAAACTTTCACATTCAGAACAATCAGCCGGATAGCCTGTTATGACAGATT
CTTGAGTTCCATCTGTAGTGTCATGCTGATCCTGGCAGTCAGTGGATCAGAGTTGGAGTAGCATTTATCCACTGTATTAGTATACTTTGT
ACTTGGTGTTTGTTCAACGCATTACTTTTTTGAATTTTTTTGTTTTTTGAAGACAAGGGCTTGCCCTGGAGTGCAGTGGCATGATCTTGG
CTCACTGCAGCCTCGAGCTCCTGGGCTCAACTCAGTCTTCCCACCTCATCCTCTTAAATAGCTGGGACTACAGGCACGTGCTGCTACACC
CTGCTATTGTCTGTTTGTTTGTTTGAGACTGAGTTTTGCTCTTGTTGCCCAGGCTGGAGTGCAATGGCACAATCTTGGCTCACCACAGCC
TTTTTTATGAGACTGAGTTTTGCTCTTGTTGCCCAGGCTGGAGTGCAATGGCACGATCTTGGCTCACCACAACCTCCACTTCCTGGGTTC
AAGCAATTCTTCTGCCTCAGCCTCCCGAGTAGCTGAGATTACAGGCATGCGCCACCATGCCTGGCTAATTTTTTTTTTTTGTATTTTTAG
TAGAGATGGGGTTTCACCGTGTTGGTCAGGCTGGTCTTGAACTCCTGACCTCAGGTGATCCACCCCCCTTGGCCTCCCAAAGAGCTGGGA
TTACAGGCATGAGCCACTGCGCCTAGCCCCACCCCCCCTACTTTTTTTTTTTTTTTTTTTTTAATTTTTTGTGTAGCCAAAAGATCTCAC
TCTGTTGCCCAGACTGCTCTCAAAACTCCTGGCCTTAAGTGATTCCCCTGCCTCAGTCTCCCAAAGTGCTGGGATTATAGGCATGAGCCA
CCATGCCTGTCCATTATTTCTTTATAGTGACTATTATATGTAGGCAATGTATAATTGGTAGAACATAGTCTATGAAACAGTGCGTTAATT
GTGGGCAGTGAAGAATCATTGAAGTTGTGAAATTTGTATTTTAACTAGATCATTGTAGTATGGCAAAACGGTTAGGAAAGAGAAAGCTAT
CTTGACTAACTGTTTATGCTATGAGATACTGACTGATGTACATGTACATTTAGTGTTTCTTTAGGTATACCTGACTTATTCATTGAACAC
CTATCCACTGATCTCAAAAGTATTCCTCAGGGTAGTCTCCATTCCTGTCATTTTTCCTCCTATTCATGAGACGGAAAAATTATGACCATG
GTACAGAGTTGTATCAAGGAAATGAAGAACTAGAACATTGAATTGAAAGGTTTTGAAAGGGTTCACAATTTCTTTTCATTTTCTATTAAT

>59208_59208_3_NIPBL-NUP155_NIPBL_chr5_37027514_ENST00000448238_NUP155_chr5_37310845_ENST00000231498_length(amino acids)=2533AA_BP=1954
MNGDMPHVPITTLAGIASLTDLLNQLPLPSPLPATTTKSLLFNARIAEEVNCLLACRDDNLVSQLVHSLNQVSTDHIELKDNLGSDDPEG
DIPVLLQAVLARSPNVFREKSMQNRYVQSGMMMSQYKLSQNSMHSSPASSNYQQTTISHSPSSRFVPPQTSSGNRFMPQQNSPVPSPYAP
QSPAGYMPYSHPSSYTTHPQMQQASVSSPIVAGGLRNIHDNKVSGPLSGNSANHHADNPRHGSSEDYLHMVHRLSSDDGDSSTMRNAASF
PLRSPQPVCSPAGSEGTPKGSRPPLILQSQSLPCSSPRDVPPDILLDSPERKQKKQKKMKLGKDEKEQSEKAAMYDIISSPSKDSTKLTL
RLSRVRSSDMDQQEDMISGVENSNVSENDIPFNVQYPGQTSKTPITPQDINRPLNAAQCLSQQEQTAFLPANQVPVLQQNTSVAAKQPQT
SVVQNQQQISQQGPIYDEVELDALAEIERIERESAIERERFSKEVQDKDKPLKKRKQDSYPQEAGGATGGNRPASQETGSTGNGSRPALM
VSIDLHQAGRVDSQASITQDSDSIKKPEEIKQCNDAPVSVLQEDIVGSLKSTPENHPETPKKKSDPELSKSEMKQSESRLAESKPNENRL
VETKSSENKLETKVETQTEELKQNESRTTECKQNESTIVEPKQNENRLSDTKPNDNKQNNGRSETTKSRPETPKQKGESRPETPKQKSDG
HPETPKQKGDGRPETPKQKGESRPETPKQKNEGRPETPKHRHDNRRDSGKPSTEKKPEVSKHKQDTKSDSPRLKSERAEALKQRPDGRSV
SESLRRDHDNKQKSDDRGESERHRGDQSRVRRPETLRSSSRNEHGIKSDSSKTDKLERKHRHESGDSRERPSSGEQKSRPDSPRVKQGDS
NKSRSDKLGFKSPTSKDDKRTEGNKSKVDTNKAHPDNKAEFPSYLLGGRSGALKNFVIPKIKRDKDGNVTQETKKMEMKGEPKDKVEKIG
LVEDLNKGAKPVVVLQKLSLDDVQKLIKDREDKSRSSLKPIKNKPSKSNKGSIDQSVLKELPPELLAEIESTMPLCERVKMNKRKRSTVN
EKPKYAEISSDEDNDSDEAFESSRKRHKKDDDKAWEYEERDRRSSGDHRRSGHSHEGRRSSGGGRYRNRSPSDSDMEDYSPPPSLSEVAR
KMKKKEKQKKRKAYEPKLTPEEMMDSSTFKRFTASIENILDNLEDMDFTAFGDDDEIPQELLLGKHQLNELGSESAKIKAMGIMDKLSTD
KTVKVLNILEKNIQDGSKLSTLLNHNNDTEEEERLWRDLIMERVTKSADACLTTINIMTSPNMPKAVYIEDVIERVIQYTKFHLQNTLYP
QYDPVYRLDPHGGGLLSSKAKRAKCSTHKQRVIVMLYNKVCDIVSSLSELLEIQLLTDTTILQVSSMGITPFFVENVSELQLCAIKLVTA
VFSRYEKHRQLILEEIFTSLARLPTSKRSLRNFRLNSSDMDGEPMYIQMVTALVLQLIQCVVHLPSSEKDSNAEEDSNKKIDQDVVITNS
YETAMRTAQNFLSIFLKKCGSKQGEEDYRPLFENFVQDLLSTVNKPEWPAAELLLSLLGRLLVHQFSNKSTEMALRVASLDYLGTVAARL
RKDAVTSKMDQGSIERILKQVSGGEDEIQQLQKALLDYLDENTETDPSLVFSRKFYIAQWFRDTTLETEKAMKSQKDEESSEGTHHAKEI
ETTGQIMHRAENRKKFLRSIIKTTPSQFSTLKMNSDTVDYDDACLIVRYLASMRPFAQSFDIYLTQILRVLGENAIAVRTKAMKCLSEVV
AVDPSILARLDMQRGVHGRLMDNSTSVREAAVELLGRFVLCRPQLAEQYYDMLIERILDTGISVRKRVIKILRDICIEQPTFPKITEMCV
KMIRRVNDEEGIKKLVNETFQKLWFTPTPHNDKEAMTRKILNITDVVAACRDTGYDWFEQLLQNELQEQLKITTFKDLVIRDKELTGALI
ASLINCYIRDNAAVDGISLHLQDICPLLYSTDDAICSKANELLQRSRQVQNKTEKERMLRESLKEYQKISNQVDLSNVCAQYRQVRFYEG
VVELSLTAAEKKDPQGLGLHFYKHGEPEEDIVGLQAFQERLNSYKCITDTLQELVNQSKAAPQSPSVPKKPGPPVLSSDPNMLSNEEAGH
HFEQMLKLSQRSKDELFSIALYNWLIQVDLADKLLQVASPFLEPHLVRMAKVDQNRVRYMDLLWRYYEKNRSFSNAARVLSRLADMHSTE
ISLQQRLEYIARAILSAKSSTAISSIAADGEFLHELEEKMEVARIQLQIQETLQRQYSHHSSVQDAVSQLDSELMDITKLYGEFADPFKL
AECKLAIIHCAGYSDPILVQTLWQDIIEKELSDSVTLSSSDRMHALSLKIVLLGKIYAGTPRFFPLDFIVQFLEQQVCTLNWDVGFVIQT
MNEIGVPLPRLLEVYDQLFKSRDPFWNRMKKPLHLLDCIHVLLIRYVENPSQVLNCERRRFTNLCLDAVCGYLVELQSMSSSVAVQAITG

--------------------------------------------------------------
>59208_59208_4_NIPBL-NUP155_NIPBL_chr5_37027514_ENST00000448238_NUP155_chr5_37310845_ENST00000381843_length(transcript)=8131nt_BP=6330nt
ACGGAACGAGAGAGAGACACACACAGGGCTCCTTCCCCCCGCCCTCCCCCCCCTCCCTCCGTCGGTACCGACTCACCCGACACCACCAAG
CCGCAGGGAGGGACGCCCCCGCCGACAGGAGAATTGGTTCCCGGGCCCGCGGCGATGCCCCCCCGGTAGCTCGGGCCCGTGGTCGGGTGT
TTGTGAGTGTTTCTATGTGGGAGAAGGAGGAGGAGGAGGAAGAAGAAGCAACGATTTGTCTTCTCGGCTGGTCTCCCCCCGGCTCTACAT
GTTCCCCGCACTGAGGAGACGGAAGAGGAGCCGTAGCCACCCCCCCTCCCGGCCCGGATTATAGTCTCTCGCCACAGCGGCCTCGGCCTC
CCCTTGGATTCAGACGCCGATTCGCCCAGTGTTTGGGAAATGGGAAGTAATGACAGCTGGCACCTGAACTAAGTACTTTTATAGGCAACA
CCATTCCAGAAATTCAGGATGAATGGGGATATGCCCCATGTCCCCATTACTACTCTTGCGGGGATTGCTAGTCTCACAGACCTCCTGAAC
CAGCTGCCTCTTCCATCTCCTTTACCTGCTACAACTACAAAGAGCCTTCTCTTTAATGCACGAATAGCAGAAGAGGTGAACTGCCTTTTG
GCTTGTAGGGATGACAATTTGGTTTCACAGCTTGTCCATAGCCTCAACCAGGTATCAACAGATCACATAGAGTTGAAAGATAACCTTGGC
AGTGATGACCCAGAAGGTGACATACCAGTCTTGTTGCAGGCCGTCCTGGCAAGGAGTCCTAATGTTTTCAGGGAGAAAAGCATGCAGAAC
AGATATGTACAAAGTGGAATGATGATGTCTCAGTATAAACTTTCTCAGAATTCCATGCACAGTAGTCCTGCATCTTCCAATTATCAACAA
ACCACTATCTCACATAGCCCCTCCAGCCGGTTTGTGCCACCACAGACAAGCTCTGGGAACAGATTTATGCCACAGCAAAATAGCCCAGTG
CCTAGTCCATACGCCCCACAAAGCCCTGCAGGATACATGCCATATTCCCATCCTTCAAGTTACACAACACATCCACAGATGCAACAAGCA
TCGGTATCAAGTCCCATTGTTGCAGGTGGTTTGAGAAACATACATGATAATAAAGTTTCTGGTCCGTTGTCTGGCAATTCAGCTAATCAT
CATGCTGATAATCCTAGACATGGTTCAAGTGAGGACTACCTACACATGGTGCACAGGCTAAGTAGTGACGATGGAGATTCTTCAACAATG
AGGAATGCTGCATCTTTTCCCTTGAGATCTCCACAGCCAGTATGCTCCCCTGCTGGAAGTGAAGGAACTCCTAAAGGCTCAAGACCACCT
TTAATCCTACAATCTCAGTCTCTACCTTGTTCATCACCTCGAGATGTTCCACCAGATATCTTGCTAGATTCTCCAGAAAGAAAACAAAAG
AAGCAGAAGAAAATGAAATTAGGCAAGGATGAAAAAGAGCAGAGTGAGAAAGCGGCAATGTATGATATAATTAGTTCTCCATCCAAGGAC
TCTACTAAACTTACATTAAGACTTTCTCGTGTAAGGTCTTCAGACATGGACCAGCAAGAGGATATGATTTCTGGTGTGGAAAATAGCAAT
GTTTCAGAAAATGATATTCCTTTTAATGTGCAGTACCCAGGACAGACTTCAAAAACACCCATTACTCCACAAGATATAAACCGCCCACTA
AATGCTGCTCAATGTTTGTCGCAGCAAGAACAAACAGCATTCCTTCCAGCAAATCAAGTGCCTGTTTTACAACAGAACACTTCAGTTGCT
GCAAAACAACCCCAGACTTCTGTGGTACAGAATCAACAACAGATATCACAACAGGGACCTATATATGATGAAGTGGAATTGGATGCATTG
GCTGAAATTGAGCGAATAGAGAGAGAATCAGCTATTGAAAGGGAGCGCTTCTCAAAAGAAGTTCAAGATAAAGATAAGCCTTTGAAAAAA
AGAAAACAAGATTCTTACCCACAGGAGGCTGGGGGTGCTACAGGAGGTAATAGACCAGCTTCTCAGGAGACGGGTTCTACGGGAAATGGG
TCAAGGCCAGCATTAATGGTTAGCATTGATCTTCATCAGGCAGGAAGAGTGGACTCTCAGGCTTCTATAACTCAGGATTCAGACTCCATA
AAAAAGCCTGAAGAAATCAAACAATGTAATGATGCACCTGTTTCTGTTCTTCAGGAAGATATTGTTGGAAGTCTTAAATCTACACCAGAA
AACCATCCTGAGACACCTAAAAAAAAGTCTGATCCTGAGCTTTCAAAGAGTGAAATGAAACAAAGTGAAAGTAGATTAGCAGAATCTAAA
CCAAATGAAAACCGATTGGTGGAGACAAAATCAAGTGAAAATAAGTTAGAAACTAAAGTTGAGACCCAAACAGAAGAACTTAAACAGAAT
GAGAGCAGAACAACTGAATGCAAACAAAACGAGAGCACCATAGTTGAGCCTAAACAAAATGAAAATAGACTGTCTGACACAAAACCAAAT
GACAACAAACAAAATAATGGCAGATCAGAAACAACAAAATCAAGGCCTGAAACCCCAAAGCAAAAGGGTGAAAGCCGGCCTGAGACTCCA
AAACAAAAGAGTGATGGGCATCCTGAAACCCCAAAACAGAAGGGTGATGGAAGGCCTGAAACTCCAAAGCAAAAAGGTGAGAGCCGCCCT
GAAACTCCAAAGCAAAAAAATGAAGGGCGACCTGAAACACCAAAACACAGGCATGACAATAGGAGGGATTCTGGAAAGCCATCTACAGAG
AAAAAACCTGAAGTGTCTAAACATAAACAAGATACTAAATCTGACTCACCTCGGTTAAAATCAGAACGAGCTGAAGCCTTAAAGCAGAGA
CCTGATGGGCGATCTGTTTCTGAGTCACTAAGACGTGACCATGATAATAAACAAAAATCAGATGACAGGGGTGAATCAGAGCGACATCGA
GGGGATCAGTCTAGGGTTCGAAGACCAGAAACATTGAGATCCTCTAGTAGAAATGAACATGGCATTAAATCTGATAGTTCAAAAACTGAT
AAACTAGAACGAAAACACAGGCATGAATCAGGGGACTCAAGGGAAAGACCATCTTCTGGGGAACAAAAATCAAGACCTGACAGTCCTCGT
GTTAAACAAGGAGATTCTAATAAATCAAGATCTGATAAACTTGGTTTTAAATCACCAACTAGTAAAGATGACAAAAGGACAGAGGGTAAC
AAGAGTAAAGTAGACACTAATAAAGCACACCCTGACAATAAGGCAGAATTTCCAAGTTATTTGTTGGGGGGCAGGTCTGGTGCGTTGAAA
AATTTTGTCATTCCGAAAATCAAGAGGGATAAAGATGGCAATGTTACTCAGGAGACAAAGAAAATGGAAATGAAAGGAGAGCCGAAAGAC
AAAGTAGAAAAAATAGGATTAGTTGAAGATCTAAATAAAGGAGCTAAGCCTGTAGTTGTGCTACAAAAACTGTCTTTGGATGATGTTCAG
AAACTTATTAAAGATAGAGAGGACAAATCAAGAAGTTCCCTTAAACCTATCAAGAATAAACCATCAAAGTCAAATAAAGGTAGTATAGAT
CAATCAGTGTTAAAAGAATTACCCCCTGAACTCCTGGCAGAAATTGAGTCCACCATGCCACTTTGTGAACGTGTGAAAATGAACAAACGC
AAGCGTAGCACAGTTAATGAAAAGCCAAAATATGCTGAAATCAGTTCAGATGAAGATAATGATAGTGATGAAGCTTTTGAATCCTCTAGG
AAACGACATAAAAAAGATGATGATAAAGCTTGGGAATATGAAGAGCGTGACAGAAGAAGCTCTGGGGATCATAGGAGAAGTGGCCACTCT
CATGAAGGAAGAAGGAGTTCAGGTGGTGGTCGTTATCGAAACCGAAGTCCGTCAGATTCTGACATGGAAGATTATTCTCCTCCTCCCAGC
CTTAGTGAGGTTGCTAGGAAAATGAAGAAAAAAGAAAAACAGAAGAAAAGGAAAGCATATGAACCAAAACTAACACCTGAAGAAATGATG
GACTCTTCAACTTTTAAGAGATTCACAGCCTCAATAGAGAATATTTTGGATAATTTGGAAGATATGGATTTTACTGCGTTTGGTGATGAT
GATGAAATTCCTCAGGAACTGCTCTTAGGAAAACATCAGCTTAATGAACTTGGCAGTGAATCTGCTAAAATAAAAGCAATGGGTATAATG
GATAAGCTTTCAACTGACAAAACTGTGAAAGTCTTAAATATCTTGGAGAAGAATATTCAGGATGGGTCAAAGCTTTCCACTTTGTTAAAT
CATAATAACGATACTGAAGAAGAAGAAAGGTTATGGAGAGACCTTATTATGGAGAGAGTTACAAAATCAGCGGATGCTTGTCTTACAACT
ATCAACATTATGACATCCCCTAACATGCCAAAAGCTGTGTACATTGAGGATGTAATTGAAAGAGTTATACAGTACACTAAATTTCATTTG
CAGAATACACTTTATCCTCAGTATGATCCTGTTTACAGATTAGATCCTCATGGAGGAGGCTTATTAAGTTCAAAAGCAAAACGGGCTAAA
TGTTCTACCCATAAGCAGAGAGTAATAGTAATGCTTTATAACAAAGTTTGTGACATTGTTAGCAGCTTATCAGAATTGCTAGAGATACAA
CTTCTTACAGACACAACAATTCTTCAGGTTTCATCTATGGGAATAACACCATTTTTTGTGGAAAATGTCAGTGAACTACAGTTGTGTGCC
ATTAAGTTAGTCACTGCAGTATTCTCAAGATATGAAAAACATAGGCAGTTAATTTTGGAAGAAATTTTTACTTCACTTGCAAGATTACCA
ACCAGCAAGAGGAGTTTAAGGAACTTCAGGTTAAACAGTAGTGATATGGATGGAGAACCTATGTATATTCAGATGGTTACAGCACTGGTT
TTACAACTTATTCAGTGTGTGGTACACTTACCATCATCAGAGAAGGACTCTAATGCAGAAGAAGATTCAAATAAAAAAATTGACCAGGAT
GTTGTCATTACTAACTCTTATGAAACAGCTATGCGAACAGCCCAAAACTTCCTCTCCATCTTCCTTAAAAAATGTGGTAGTAAGCAAGGT
GAAGAAGATTACAGACCACTGTTTGAAAATTTTGTTCAAGACCTTCTTTCAACAGTCAATAAGCCTGAATGGCCAGCTGCTGAACTACTC
CTTAGTTTGTTAGGGAGACTGTTGGTTCATCAGTTCAGTAACAAGTCAACAGAGATGGCTTTAAGAGTGGCATCTCTTGATTACCTTGGA
ACTGTTGCTGCACGGCTAAGAAAAGATGCTGTTACAAGCAAAATGGATCAAGGATCTATAGAACGCATTTTAAAACAGGTTTCAGGAGGG
GAAGATGAAATCCAACAATTACAAAAAGCATTGCTTGATTACTTGGATGAAAACACTGAGACTGATCCTTCACTAGTGTTTTCTCGTAAA
TTCTATATAGCCCAGTGGTTTCGAGACACAACTCTGGAAACAGAAAAAGCAATGAAATCACAAAAAGATGAAGAATCATCTGAAGGAACA
CATCATGCAAAGGAAATTGAGACAACTGGCCAAATTATGCATCGAGCTGAAAACCGAAAAAAGTTTCTTAGAAGCATTATCAAAACCACA
CCTTCTCAGTTTAGCACATTAAAGATGAACTCTGATACTGTGGACTATGATGATGCTTGCTTGATTGTTCGATACTTGGCCTCCATGAGG
CCGTTTGCCCAGAGCTTTGATATTTATTTGACACAGATCCTACGAGTTCTTGGTGAAAATGCAATTGCTGTTCGAACAAAAGCCATGAAG
TGTTTGTCTGAGGTTGTTGCTGTAGACCCCAGTATTCTAGCAAGGCTTGATATGCAACGAGGTGTTCATGGACGATTGATGGATAATTCG
ACTAGTGTCCGAGAAGCAGCAGTAGAATTACTAGGTCGATTTGTCCTTTGTCGACCTCAGCTTGCTGAACAGTATTATGATATGCTGATT
GAAAGAATATTGGATACTGGTATCAGTGTCAGGAAAAGAGTAATAAAGATTCTCAGAGACATTTGTATTGAACAACCAACATTTCCAAAA
ATCACAGAAATGTGTGTAAAAATGATTCGCAGAGTCAATGATGAAGAGGGCATTAAGAAATTAGTAAATGAAACATTCCAGAAACTCTGG
TTTACTCCAACTCCACACAATGACAAAGAAGCAATGACAAGGAAAATTTTAAACATTACCGATGTGGTTGCAGCATGCAGAGATACTGGA
TATGACTGGTTTGAGCAACTGCTTCAAAACGAACTTCAAGAGCAGCTGAAGATCACCACCTTTAAAGATCTTGTAATCAGGGACAAAGAA
CTCACAGGGGCATTAATTGCTTCTCTTATCAACTGCTACATCAGAGATAATGCCGCTGTTGATGGCATTAGTTTACATTTACAGGATATC
TGCCCACTTCTATATAGCACTGATGATGCAATTTGTTCTAAGGCAAATGAGCTTCTCCAGCGTTCCCGACAAGTTCAAAATAAGACTGAA
AAAGAAAGAATGTTAAGGGAATCATTAAAGGAATATCAAAAAATTAGCAATCAAGTGGACCTTTCCAATGTTTGTGCTCAGTATAGACAA
GTGAGATTTTATGAGGGTGTGGTGGAACTTTCTCTTACGGCTGCAGAGAAAAAAGATCCTCAAGGTCTTGGGCTTCATTTCTATAAACAT
GGAGAACCAGAAGAAGACATAGTTGGACTTCAGGCCTTCCAAGAAAGATTAAACAGTTACAAATGCATTACAGACACACTTCAAGAACTG
GTAAATCAAAGTAAGGCCGCTCCTCAGTCTCCCAGTGTACCCAAAAAACCTGGTCCTCCAGTGTTGTCATCTGATCCAAATATGCTGAGT
AATGAAGAAGCAGGACATCATTTTGAACAAATGCTTAAATTGTCACAGCGATCCAAGGATGAGCTCTTTAGTATTGCCCTTTATAATTGG
CTAATACAAGTCGACCTTGCAGATAAGCTGCTACAGGTTGCTTCTCCATTTCTGGAGCCACATCTAGTCCGAATGGCCAAAGTTGATCAA
AACAGAGTTCGTTATATGGATTTACTCTGGCGGTATTACGAGAAGAACAGAAGTTTCAGTAATGCTGCTCGTGTACTGTCCAGACTGGCT
GACATGCATAGCACAGAAATTTCACTTCAGCAGCGACTAGAGTACATTGCTCGAGCCATTCTTAGTGCCAAAAGTTCCACTGCCATTTCA
TCAATAGCTGCCGATGGTGAATTTCTTCATGAATTAGAAGAAAAAATGGAGGTTGCTAGGATCCAACTTCAGATACAGGAGACACTACAA
AGGCAGTATTCCCATCATTCTTCTGTACAGGATGCAGTTTCTCAGCTGGATTCTGAGCTGATGGACATAACTAAGCTTTATGGGGAATTT
GCTGACCCATTTAAACTTGCAGAGTGCAAACTTGCAATAATTCATTGTGCCGGTTATTCAGACCCTATATTGGTGCAGACACTTTGGCAA
GATATCATAGAGAAAGAATTGAGTGACAGTGTGACATTGAGCTCCTCGGATAGAATGCATGCTCTTAGTCTCAAGATTGTTCTCCTTGGC
AAAATTTATGCTGGCACACCACGCTTCTTTCCTTTAGATTTTATTGTACAGTTTTTAGAACAGCAGGTTTGTACTTTGAACTGGGATGTG
GGCTTCGTAATACAGACAATGAATGAAATTGGAGTACCATTACCTAGACTACTAGAAGTTTATGATCAGTTGTTCAAATCACGGGATCCA
TTCTGGAACAGAATGAAGAAGCCACTGCACCTTTTGGATTGTATACATGTATTATTGATAAGATATGTTGAGAATCCCAGCCAAGTTTTA
AATTGTGAAAGGAGAAGATTTACAAATCTCTGCCTGGATGCTGTTTGTGGTTACCTTGTTGAGCTCCAGTCTATGAGCTCGTCAGTAGCA
GTACAAGCCATCACTGGGAATTTTAAATCTCTTCAAGCTAAATTAGAACGGCTTCATTAATTACTGTGATATACTTTCATCCGTTTTATG

>59208_59208_4_NIPBL-NUP155_NIPBL_chr5_37027514_ENST00000448238_NUP155_chr5_37310845_ENST00000381843_length(amino acids)=2533AA_BP=1954
MNGDMPHVPITTLAGIASLTDLLNQLPLPSPLPATTTKSLLFNARIAEEVNCLLACRDDNLVSQLVHSLNQVSTDHIELKDNLGSDDPEG
DIPVLLQAVLARSPNVFREKSMQNRYVQSGMMMSQYKLSQNSMHSSPASSNYQQTTISHSPSSRFVPPQTSSGNRFMPQQNSPVPSPYAP
QSPAGYMPYSHPSSYTTHPQMQQASVSSPIVAGGLRNIHDNKVSGPLSGNSANHHADNPRHGSSEDYLHMVHRLSSDDGDSSTMRNAASF
PLRSPQPVCSPAGSEGTPKGSRPPLILQSQSLPCSSPRDVPPDILLDSPERKQKKQKKMKLGKDEKEQSEKAAMYDIISSPSKDSTKLTL
RLSRVRSSDMDQQEDMISGVENSNVSENDIPFNVQYPGQTSKTPITPQDINRPLNAAQCLSQQEQTAFLPANQVPVLQQNTSVAAKQPQT
SVVQNQQQISQQGPIYDEVELDALAEIERIERESAIERERFSKEVQDKDKPLKKRKQDSYPQEAGGATGGNRPASQETGSTGNGSRPALM
VSIDLHQAGRVDSQASITQDSDSIKKPEEIKQCNDAPVSVLQEDIVGSLKSTPENHPETPKKKSDPELSKSEMKQSESRLAESKPNENRL
VETKSSENKLETKVETQTEELKQNESRTTECKQNESTIVEPKQNENRLSDTKPNDNKQNNGRSETTKSRPETPKQKGESRPETPKQKSDG
HPETPKQKGDGRPETPKQKGESRPETPKQKNEGRPETPKHRHDNRRDSGKPSTEKKPEVSKHKQDTKSDSPRLKSERAEALKQRPDGRSV
SESLRRDHDNKQKSDDRGESERHRGDQSRVRRPETLRSSSRNEHGIKSDSSKTDKLERKHRHESGDSRERPSSGEQKSRPDSPRVKQGDS
NKSRSDKLGFKSPTSKDDKRTEGNKSKVDTNKAHPDNKAEFPSYLLGGRSGALKNFVIPKIKRDKDGNVTQETKKMEMKGEPKDKVEKIG
LVEDLNKGAKPVVVLQKLSLDDVQKLIKDREDKSRSSLKPIKNKPSKSNKGSIDQSVLKELPPELLAEIESTMPLCERVKMNKRKRSTVN
EKPKYAEISSDEDNDSDEAFESSRKRHKKDDDKAWEYEERDRRSSGDHRRSGHSHEGRRSSGGGRYRNRSPSDSDMEDYSPPPSLSEVAR
KMKKKEKQKKRKAYEPKLTPEEMMDSSTFKRFTASIENILDNLEDMDFTAFGDDDEIPQELLLGKHQLNELGSESAKIKAMGIMDKLSTD
KTVKVLNILEKNIQDGSKLSTLLNHNNDTEEEERLWRDLIMERVTKSADACLTTINIMTSPNMPKAVYIEDVIERVIQYTKFHLQNTLYP
QYDPVYRLDPHGGGLLSSKAKRAKCSTHKQRVIVMLYNKVCDIVSSLSELLEIQLLTDTTILQVSSMGITPFFVENVSELQLCAIKLVTA
VFSRYEKHRQLILEEIFTSLARLPTSKRSLRNFRLNSSDMDGEPMYIQMVTALVLQLIQCVVHLPSSEKDSNAEEDSNKKIDQDVVITNS
YETAMRTAQNFLSIFLKKCGSKQGEEDYRPLFENFVQDLLSTVNKPEWPAAELLLSLLGRLLVHQFSNKSTEMALRVASLDYLGTVAARL
RKDAVTSKMDQGSIERILKQVSGGEDEIQQLQKALLDYLDENTETDPSLVFSRKFYIAQWFRDTTLETEKAMKSQKDEESSEGTHHAKEI
ETTGQIMHRAENRKKFLRSIIKTTPSQFSTLKMNSDTVDYDDACLIVRYLASMRPFAQSFDIYLTQILRVLGENAIAVRTKAMKCLSEVV
AVDPSILARLDMQRGVHGRLMDNSTSVREAAVELLGRFVLCRPQLAEQYYDMLIERILDTGISVRKRVIKILRDICIEQPTFPKITEMCV
KMIRRVNDEEGIKKLVNETFQKLWFTPTPHNDKEAMTRKILNITDVVAACRDTGYDWFEQLLQNELQEQLKITTFKDLVIRDKELTGALI
ASLINCYIRDNAAVDGISLHLQDICPLLYSTDDAICSKANELLQRSRQVQNKTEKERMLRESLKEYQKISNQVDLSNVCAQYRQVRFYEG
VVELSLTAAEKKDPQGLGLHFYKHGEPEEDIVGLQAFQERLNSYKCITDTLQELVNQSKAAPQSPSVPKKPGPPVLSSDPNMLSNEEAGH
HFEQMLKLSQRSKDELFSIALYNWLIQVDLADKLLQVASPFLEPHLVRMAKVDQNRVRYMDLLWRYYEKNRSFSNAARVLSRLADMHSTE
ISLQQRLEYIARAILSAKSSTAISSIAADGEFLHELEEKMEVARIQLQIQETLQRQYSHHSSVQDAVSQLDSELMDITKLYGEFADPFKL
AECKLAIIHCAGYSDPILVQTLWQDIIEKELSDSVTLSSSDRMHALSLKIVLLGKIYAGTPRFFPLDFIVQFLEQQVCTLNWDVGFVIQT
MNEIGVPLPRLLEVYDQLFKSRDPFWNRMKKPLHLLDCIHVLLIRYVENPSQVLNCERRRFTNLCLDAVCGYLVELQSMSSSVAVQAITG

--------------------------------------------------------------

Top

Fusion Gene PPI Analysis for NIPBL-NUP155


check button Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in

ChiPPI page.


check button Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160)
HgeneHgene's interactorsTgeneTgene's interactors


check button - Retained PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenStill interaction with


check button - Lost PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


check button - Retained PPIs, but lost function due to frame-shift fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


Top

Related Drugs for NIPBL-NUP155


check button Drugs targeting genes involved in this fusion gene.
(DrugBank Version 5.1.8 2021-05-08)
PartnerGeneUniProtAccDrugBank IDDrug nameDrug activityDrug typeDrug status

Top

Related Diseases for NIPBL-NUP155


check button Diseases associated with fusion partners.
(DisGeNet 4.0)
PartnerGeneDisease IDDisease name# pubmedsSource