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Center for Computational Systems Medicine
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Fusion Gene Summary

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Fusion Gene ORF analysis

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Fusion Genomic Features

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Fusion Protein Features

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Fusion Gene Sequence

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Fusion Gene PPI analysis

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Related Drugs

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Related Diseases

Fusion gene:NLK-LGALS9 (FusionGDB2 ID:59350)

Fusion Gene Summary for NLK-LGALS9

check button Fusion gene summary
Fusion gene informationFusion gene name: NLK-LGALS9
Fusion gene ID: 59350
HgeneTgene
Gene symbol

NLK

LGALS9

Gene ID

51701

3965

Gene namenemo like kinasegalectin 9
Synonyms-HUAT|LGALS9A
Cytomap

17q11.2

17q11.2

Type of geneprotein-codingprotein-coding
Descriptionserine/threonine-protein kinase NLKgalectin-9ecalectingal-9lectin, galactoside-binding, soluble, 9tumor antigen HOM-HD-21urate transporter/channel protein
Modification date2020031320200315
UniProtAcc

Q9UBE8

Q3B8N2

Ensembl transtripts involved in fusion geneENST00000583517, ENST00000407008, 
ENST00000582037, 		ENST00000302228, 
ENST00000310394, ENST00000313648, 
ENST00000395473, ENST00000448970, 
ENST00000413914, 
Fusion gene scores* DoF score18 X 10 X 9=16208 X 8 X 5=320
# samples 209
** MAII scorelog2(20/1620*10)=-3.01792190799726
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0		log2(9/320*10)=-1.83007499855769
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0
Context

PubMed: NLK [Title/Abstract] AND LGALS9 [Title/Abstract] AND fusion [Title/Abstract]

Most frequent breakpointNLK(26370357)-LGALS9(25967598), # samples:2
Anticipated loss of major functional domain due to fusion event.
* DoF score (Degree of Frequency) = # partners X # break points X # cancer types
** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)

check button Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez
PartnerGeneGO IDGO termPubMed ID
HgeneNLK

GO:0050821

protein stabilization

25512613

TgeneLGALS9

GO:0006954

inflammatory response

23817958

TgeneLGALS9

GO:0007565

female pregnancy

23242525

TgeneLGALS9

GO:0010628

positive regulation of gene expression

16116184

TgeneLGALS9

GO:0010629

negative regulation of gene expression

23408620

TgeneLGALS9

GO:0032673

regulation of interleukin-4 production

16116184

TgeneLGALS9

GO:0032674

regulation of interleukin-5 production

16116184

TgeneLGALS9

GO:0032689

negative regulation of interferon-gamma production

23408620

TgeneLGALS9

GO:0032753

positive regulation of interleukin-4 production

20209097

TgeneLGALS9

GO:0032834

positive regulation of CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation involved in immune response

20209097

TgeneLGALS9

GO:0034134

toll-like receptor 2 signaling pathway

16116184

TgeneLGALS9

GO:0034142

toll-like receptor 4 signaling pathway

16116184

TgeneLGALS9

GO:0038066

p38MAPK cascade

16116184

TgeneLGALS9

GO:0045953

negative regulation of natural killer cell mediated cytotoxicity

23408620

TgeneLGALS9

GO:0046598

positive regulation of viral entry into host cell

21670307

TgeneLGALS9

GO:0050718

positive regulation of interleukin-1 beta secretion

20209097

TgeneLGALS9

GO:0060135

maternal process involved in female pregnancy

25578313

TgeneLGALS9

GO:0070241

positive regulation of activated T cell autonomous cell death

20209097

TgeneLGALS9

GO:0070371

ERK1 and ERK2 cascade

16116184

TgeneLGALS9

GO:0070555

response to interleukin-1

23817958

TgeneLGALS9

GO:0071346

cellular response to interferon-gamma

23817958

TgeneLGALS9

GO:0071636

positive regulation of transforming growth factor beta production

20209097

TgeneLGALS9

GO:1902715

positive regulation of interferon-gamma secretion

20209097

TgeneLGALS9

GO:1904469

positive regulation of tumor necrosis factor secretion

20209097

TgeneLGALS9

GO:2000562

negative regulation of CD4-positive, alpha-beta T cell proliferation

20209097

TgeneLGALS9

GO:2000563

positive regulation of CD4-positive, alpha-beta T cell proliferation

16116184

TgeneLGALS9

GO:2000667

positive regulation of interleukin-13 secretion

20209097

TgeneLGALS9

GO:2000670

positive regulation of dendritic cell apoptotic process

16116184

TgeneLGALS9

GO:2001181

positive regulation of interleukin-10 secretion

16116184|20209097

TgeneLGALS9

GO:2001190

positive regulation of T cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell

16116184


check buttonFusion gene breakpoints across NLK (5'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check buttonFusion gene breakpoints across LGALS9 (3'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check button Fusion gene information from two resources (ChiTars 5.0 and ChimerDB 4.0)
* All genome coordinats were lifted-over on hg19.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
SourceDiseaseSampleHgeneHchrHbpHstrandTgeneTchrTbpTstrand
ChimerDB4BRCATCGA-AR-A1AJ-01ANLKchr17

26370357

+LGALS9chr17

25967598

+


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Fusion Gene ORF analysis for NLK-LGALS9

check button Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
ORFHenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrand
3UTR-3CDSENST00000583517ENST00000302228NLKchr17

26370357

+LGALS9chr17

25967598

+
3UTR-3CDSENST00000583517ENST00000310394NLKchr17

26370357

+LGALS9chr17

25967598

+
3UTR-3CDSENST00000583517ENST00000313648NLKchr17

26370357

+LGALS9chr17

25967598

+
3UTR-3CDSENST00000583517ENST00000395473NLKchr17

26370357

+LGALS9chr17

25967598

+
3UTR-3UTRENST00000583517ENST00000448970NLKchr17

26370357

+LGALS9chr17

25967598

+
3UTR-intronENST00000583517ENST00000413914NLKchr17

26370357

+LGALS9chr17

25967598

+
5CDS-3UTRENST00000407008ENST00000448970NLKchr17

26370357

+LGALS9chr17

25967598

+
5CDS-3UTRENST00000582037ENST00000448970NLKchr17

26370357

+LGALS9chr17

25967598

+
5CDS-intronENST00000407008ENST00000413914NLKchr17

26370357

+LGALS9chr17

25967598

+
5CDS-intronENST00000582037ENST00000413914NLKchr17

26370357

+LGALS9chr17

25967598

+
In-frameENST00000407008ENST00000302228NLKchr17

26370357

+LGALS9chr17

25967598

+
In-frameENST00000407008ENST00000310394NLKchr17

26370357

+LGALS9chr17

25967598

+
In-frameENST00000407008ENST00000313648NLKchr17

26370357

+LGALS9chr17

25967598

+
In-frameENST00000407008ENST00000395473NLKchr17

26370357

+LGALS9chr17

25967598

+
In-frameENST00000582037ENST00000302228NLKchr17

26370357

+LGALS9chr17

25967598

+
In-frameENST00000582037ENST00000310394NLKchr17

26370357

+LGALS9chr17

25967598

+
In-frameENST00000582037ENST00000313648NLKchr17

26370357

+LGALS9chr17

25967598

+
In-frameENST00000582037ENST00000395473NLKchr17

26370357

+LGALS9chr17

25967598

+

check buttonORFfinder result based on the fusion transcript sequence of in-frame fusion genes.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandSeq length
(transcript)		BP loci
(transcript)		Predicted start
(transcript)		Predicted stop
(transcript)		Seq length
(amino acids)
ENST00000407008NLKchr1726370357+ENST00000310394LGALS9chr1725967598+255211767181980420
ENST00000407008NLKchr1726370357+ENST00000395473LGALS9chr1725967598+269111767182112464
ENST00000407008NLKchr1726370357+ENST00000302228LGALS9chr1725967598+259511767182016432
ENST00000407008NLKchr1726370357+ENST00000313648LGALS9chr1725967598+230511767181785355
ENST00000582037NLKchr1726370357+ENST00000310394LGALS9chr1725967598+1869493351297420
ENST00000582037NLKchr1726370357+ENST00000395473LGALS9chr1725967598+2008493351429464
ENST00000582037NLKchr1726370357+ENST00000302228LGALS9chr1725967598+1912493351333432
ENST00000582037NLKchr1726370357+ENST00000313648LGALS9chr1725967598+1622493351102355

check buttonDeepORF prediction of the coding potential based on the fusion transcript sequence of in-frame fusion genes. DeepORF is a coding potential classifier based on convolutional neural network by comparing the real Ribo-seq data. If the no-coding score < 0.5 and coding score > 0.5, then the in-frame fusion transcript is predicted as being likely translated.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandNo-coding scoreCoding score
ENST00000407008ENST00000310394NLKchr1726370357+LGALS9chr1725967598+0.117267480.8827325
ENST00000407008ENST00000395473NLKchr1726370357+LGALS9chr1725967598+0.119932640.8800674
ENST00000407008ENST00000302228NLKchr1726370357+LGALS9chr1725967598+0.1121008840.8878991
ENST00000407008ENST00000313648NLKchr1726370357+LGALS9chr1725967598+0.229709790.7702902
ENST00000582037ENST00000310394NLKchr1726370357+LGALS9chr1725967598+0.167522530.83247745
ENST00000582037ENST00000395473NLKchr1726370357+LGALS9chr1725967598+0.176923690.8230763
ENST00000582037ENST00000302228NLKchr1726370357+LGALS9chr1725967598+0.167144050.8328559
ENST00000582037ENST00000313648NLKchr1726370357+LGALS9chr1725967598+0.19419040.8058096

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Fusion Genomic Features for NLK-LGALS9


check buttonFusionAI prediction of the potential fusion gene breakpoint based on the pre-mature RNA sequence context (+/- 5kb of individual partner genes, total 20kb length sequence). FusionAI is a fusion gene breakpoint classifier based on convolutional neural network by comparing the fusion positive and negative sequence context of ~ 20K fusion gene data. From here, we can have the relative potentency of the 20K genomic sequence how individual sequnce will be likely used as the gene fusion breakpoints.
HgeneHchrHbpHstrandTgeneTchrTbpTstrand1-pp (fusion gene breakpoint)
NLKchr1726370357+LGALS9chr1725967597+0.0091402950.9908597
NLKchr1726370357+LGALS9chr1725967597+0.0091402950.9908597

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions. We integrated a total of 44 different types of human genomic feature loci information across five big categories including virus integration sites, repeats, structural variants, chromatin states, and gene expression regulation. More details are in help page.
genomic feature

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions that are ovelapped with the top 1% feature importance score regions. More details are in help page.
genomic feature of top 1%

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Fusion Protein Features for NLK-LGALS9


check button Four levels of functional features of fusion genes
Go to FGviewer search page for the most frequent breakpoint (https://ccsmweb.uth.edu/FGviewer/chr17:26370357/chr17:25967598)
- FGviewer provides the online visualization of the retention search of the protein functional features across DNA, RNA, protein, and pathological levels.
- How to search
1. Put your fusion gene symbol.
2. Press the tab key until there will be shown the breakpoint information filled.
4. Go down and press 'Search' tab twice.
4. Go down to have the hyperlink of the search result.
5. Click the hyperlink.
6. See the FGviewer result for your fusion gene.
FGviewer

check buttonMain function of each fusion partner protein. (from UniProt)
HgeneTgene
NLK

Q9UBE8

LGALS9

Q3B8N2

FUNCTION: Serine/threonine-protein kinase that regulates a number of transcription factors with key roles in cell fate determination. Positive effector of the non-canonical Wnt signaling pathway, acting downstream of WNT5A, MAP3K7/TAK1 and HIPK2. Negative regulator of the canonical Wnt/beta-catenin signaling pathway. Binds to and phosphorylates TCF7L2/TCF4 and LEF1, promoting the dissociation of the TCF7L2/LEF1/beta-catenin complex from DNA, as well as the ubiquitination and subsequent proteolysis of LEF1. Together these effects inhibit the transcriptional activation of canonical Wnt/beta-catenin target genes. Negative regulator of the Notch signaling pathway. Binds to and phosphorylates NOTCH1, thereby preventing the formation of a transcriptionally active ternary complex of NOTCH1, RBPJ/RBPSUH and MAML1. Negative regulator of the MYB family of transcription factors. Phosphorylation of MYB leads to its subsequent proteolysis while phosphorylation of MYBL1 and MYBL2 inhibits their interaction with the coactivator CREBBP. Other transcription factors may also be inhibited by direct phosphorylation of CREBBP itself. Acts downstream of IL6 and MAP3K7/TAK1 to phosphorylate STAT3, which is in turn required for activation of NLK by MAP3K7/TAK1. Upon IL1B stimulus, cooperates with ATF5 to activate the transactivation activity of C/EBP subfamily members. Phosphorylates ATF5 but also stabilizes ATF5 protein levels in a kinase-independent manner (PubMed:25512613). {ECO:0000250|UniProtKB:O54949, ECO:0000269|PubMed:12482967, ECO:0000269|PubMed:14960582, ECO:0000269|PubMed:15004007, ECO:0000269|PubMed:15764709, ECO:0000269|PubMed:20061393, ECO:0000269|PubMed:20118921, ECO:0000269|PubMed:20874444, ECO:0000269|PubMed:21454679, ECO:0000269|PubMed:25512613}.FUNCTION: Binds galactosides. {ECO:0000250}.

check buttonRetention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at

download page


* Minus value of BPloci means that the break pointn is located before the CDS.
- In-frame and retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneNLKchr17:26370357chr17:25967598ENST00000407008+111106_111152528.0Compositional biasNote=Poly-Ala
HgeneNLKchr17:26370357chr17:25967598ENST00000407008+111115_119152528.0Compositional biasNote=Poly-Ala
HgeneNLKchr17:26370357chr17:25967598ENST00000407008+11122_25152528.0Compositional biasNote=Poly-Ala
HgeneNLKchr17:26370357chr17:25967598ENST00000407008+11127_34152528.0Compositional biasNote=Poly-His
HgeneNLKchr17:26370357chr17:25967598ENST00000407008+11142_48152528.0Compositional biasNote=Poly-His
HgeneNLKchr17:26370357chr17:25967598ENST00000407008+11171_83152528.0Compositional biasNote=Poly-Ala
HgeneNLKchr17:26370357chr17:25967598ENST00000407008+111144_152152528.0Nucleotide bindingATP
TgeneLGALS9chr17:26370357chr17:25967598ENST00000302228110227_35543324.0DomainGalectin 2
TgeneLGALS9chr17:26370357chr17:25967598ENST00000395473111227_35543356.0DomainGalectin 2
TgeneLGALS9chr17:26370357chr17:25967598ENST00000302228110287_29343324.0RegionBeta-galactoside binding 2
TgeneLGALS9chr17:26370357chr17:25967598ENST0000030222811082_8843324.0RegionNote=Beta-galactoside binding 1
TgeneLGALS9chr17:26370357chr17:25967598ENST00000395473111287_29343356.0RegionBeta-galactoside binding 2
TgeneLGALS9chr17:26370357chr17:25967598ENST0000039547311182_8843356.0RegionNote=Beta-galactoside binding 1

- In-frame and not-retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneNLKchr17:26370357chr17:25967598ENST00000407008+111138_427152528.0DomainProtein kinase
HgeneNLKchr17:26370357chr17:25967598ENST00000407008+111298_300152528.0MotifNote=TQE
HgeneNLKchr17:26370357chr17:25967598ENST00000407008+111428_527152528.0RegionRequired for homodimerization and kinase activation and localization to the nucleus
TgeneLGALS9chr17:26370357chr17:25967598ENST0000030222811017_14843324.0DomainGalectin 1
TgeneLGALS9chr17:26370357chr17:25967598ENST0000039547311117_14843356.0DomainGalectin 1


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Fusion Gene Sequence for NLK-LGALS9


check button For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. To have fusion amino acid sequence, we ran ORFfinder and chose the longest ORF among the all predicted ones.
>59350_59350_1_NLK-LGALS9_NLK_chr17_26370357_ENST00000407008_LGALS9_chr17_25967598_ENST00000302228_length(transcript)=2595nt_BP=1176nt
CCCCGGCTCTCTTTCTCCTCTCTGTCCTGCTGTCGCCTCCTCTCCTCACTCCAGCCTCCTTCCCTGGCTTATTCTGCCCAGGAAAGTTTG
GAACCCCCGCCCCCCCTCCCCAATCAGGTCAACCTGACTAGGAGTAGGGGGAGATGTAGGAAGGCCTGAGAGTTCGGGGGGGGGGAAGCT
GGAAGCTGGTTTCCCAGAAAATTTCCCCCCATCTTCTCCATTTAGGGTGGTGGGAATTTTTTTTAATCCTGTTTTTGAGGAGGTGGTAGG
TGTTTAGAAAAGGATGTGGGAATGGAAGGGGTAGATGAGTCAACCCTCTTTCAAGATTCCAAGGGTGGTGTGTTACCTGATCCTTTTCGT
GTGTGGAGTTCAGGGGGTCGGGAGGTTTGGCCTTTATTCCCACATTCAAAGTTGGAACCTCCCCCAAATTAAGAATGGAGTTTTAGTACC
CACTTGTGGCAGGAATCCTGGGGGGAAGGGGTCCTTTTTTCCTTTTTCTTTTCTTTTTTCCCTTTTTTTTCCTTTTGGCAACCCACACCC
TTCCACACACGCTCACCCCAAAATTAAACACCAAGATCCTCTAACTTGTTTGGATTGACTGATGAAGACATAAAGCTCTATGTTTTTTGA
GGTGGAGTGAGTGGTTTTTCTTCATTTTTAAATGGCCAAATGACAGCTTGACCCAGTTTGCTTTCCAATCAAAGGGCATTTATTTTGAAT
GTCTCTTTGTGGCGCAAGAGCCAACGCAAAAATGATGGCGGCTTACAATGGCGGTACATCTGCAGCAGCAGCAGGTCACCACCACCACCA
TCACCACCACCTTCCACACCTCCCTCCTCCTCACCTGCACCACCACCACCACCCTCAACACCATCTTCATCCGGGGTCGGCTGCCGCTGT
ACACCCTGTACAGCAGCACACCTCTTCGGCAGCTGCGGCAGCCGCAGCAGCGGCTGCAGCTGCAGCCATGTTAAACCCTGGGCAACAACA
GCCATATTTCCCATCACCGGCACCGGGGCAGGCTCCTGGACCAGCTGCAGCAGCCCCAGCTCAGGTACAGGCTGCCGCAGCTGCTACAGT
TAAGGCGCACCATCATCAGCACTCGCATCATCCACAGCAGCAGCTGGATATTGAGCCGGATAGACCTATTGGATATGGAGCCTTTGGTGT
TGTCTGGTTTGCTGTGAACTTTCAGACTGGCTTCAGTGGAAATGACATTGCCTTCCACTTCAACCCTCGGTTTGAAGATGGAGGGTACGT
GGTGTGCAACACGAGGCAGAACGGAAGCTGGGGGCCCGAGGAGAGGAAGACACACATGCCTTTCCAGAAGGGGATGCCCTTTGACCTCTG
CTTCCTGGTGCAGAGCTCAGATTTCAAGGTGATGGTGAACGGGATCCTCTTCGTGCAGTACTTCCACCGCGTGCCCTTCCACCGTGTGGA
CACCATCTCCGTCAATGGCTCTGTGCAGCTGTCCTACATCAGCTTCCAGCCTCCCGGCGTGTGGCCTGCCAACCCGGCTCCCATTACCCA
GACAGTCATCCACACAGTGCAGAGCGCCCCTGGACAGATGTTCTCTACTCCCGCCATCCCACCTATGATGTACCCCCACCCCGCCTATCC
GATGCCTTTCATCACCACCATTCTGGGAGGGCTGTACCCATCCAAGTCCATCCTCCTGTCAGGCACTGTCCTGCCCAGTGCTCAGAGGTT
CCACATCAACCTGTGCTCTGGGAACCACATCGCCTTCCACCTGAACCCCCGTTTTGATGAGAATGCTGTGGTCCGCAACACCCAGATCGA
CAACTCCTGGGGGTCTGAGGAGCGAAGTCTGCCCCGAAAAATGCCCTTCGTCCGTGGCCAGAGCTTCTCAGTGTGGATCTTGTGTGAAGC
TCACTGCCTCAAGGTGGCCGTGGATGGTCAGCACCTGTTTGAATACTACCATCGCCTGAGGAACCTGCCCACCATCAACAGACTGGAAGT
GGGGGGCGACATCCAGCTGACCCATGTGCAGACATAGGCGGCTTCCTGGCCCTGGGGCCGGGGGCTGGGGTGTGGGGCAGTCTGGGTCCT
CTCATCATCCCCACTTCCCAGGCCCAGCCTTTCCAACCCTGCCTGGGATCTGGGCTTTAATGCAGAGGCCATGTCCTTGTCTGGTCCTGC
TTCTGGCTACAGCCACCCTGGAACGGAGAAGGCAGCTGACGGGGATTGCCTTCCTCAGCCGCAGCAGCACCTGGGGCTCCAGCTGCTGGA
ATCCTACCATCCCAGGAGGCAGGCACAGCCAGGGAGAGGGGAGGAGTGGGCAGTGAAGATGAAGCCCCATGCTCAGTCCCCTCCCATCCC
CCACGCAGCTCCACCCCAGTCCCAAGCCACCAGCTGTCTGCTCCTGGTGGGAGGTGGCCTCCTCAGCCCCTCCTCTCTGACCTTTAACCT
CACTCTCACCTTGCACCGTGCACCAACCCTTCACCCCTCCTGGAAAGCAGGCCTGATGGCTTCCCACTGGCCTCCACCACCTGACCAGAG

>59350_59350_1_NLK-LGALS9_NLK_chr17_26370357_ENST00000407008_LGALS9_chr17_25967598_ENST00000302228_length(amino acids)=432AA_BP=153
MSLCGARANAKMMAAYNGGTSAAAAGHHHHHHHHLPHLPPPHLHHHHHPQHHLHPGSAAAVHPVQQHTSSAAAAAAAAAAAAAMLNPGQQ
QPYFPSPAPGQAPGPAAAAPAQVQAAAAATVKAHHHQHSHHPQQQLDIEPDRPIGYGAFGVVWFAVNFQTGFSGNDIAFHFNPRFEDGGY
VVCNTRQNGSWGPEERKTHMPFQKGMPFDLCFLVQSSDFKVMVNGILFVQYFHRVPFHRVDTISVNGSVQLSYISFQPPGVWPANPAPIT
QTVIHTVQSAPGQMFSTPAIPPMMYPHPAYPMPFITTILGGLYPSKSILLSGTVLPSAQRFHINLCSGNHIAFHLNPRFDENAVVRNTQI

--------------------------------------------------------------
>59350_59350_2_NLK-LGALS9_NLK_chr17_26370357_ENST00000407008_LGALS9_chr17_25967598_ENST00000310394_length(transcript)=2552nt_BP=1176nt
CCCCGGCTCTCTTTCTCCTCTCTGTCCTGCTGTCGCCTCCTCTCCTCACTCCAGCCTCCTTCCCTGGCTTATTCTGCCCAGGAAAGTTTG
GAACCCCCGCCCCCCCTCCCCAATCAGGTCAACCTGACTAGGAGTAGGGGGAGATGTAGGAAGGCCTGAGAGTTCGGGGGGGGGGAAGCT
GGAAGCTGGTTTCCCAGAAAATTTCCCCCCATCTTCTCCATTTAGGGTGGTGGGAATTTTTTTTAATCCTGTTTTTGAGGAGGTGGTAGG
TGTTTAGAAAAGGATGTGGGAATGGAAGGGGTAGATGAGTCAACCCTCTTTCAAGATTCCAAGGGTGGTGTGTTACCTGATCCTTTTCGT
GTGTGGAGTTCAGGGGGTCGGGAGGTTTGGCCTTTATTCCCACATTCAAAGTTGGAACCTCCCCCAAATTAAGAATGGAGTTTTAGTACC
CACTTGTGGCAGGAATCCTGGGGGGAAGGGGTCCTTTTTTCCTTTTTCTTTTCTTTTTTCCCTTTTTTTTCCTTTTGGCAACCCACACCC
TTCCACACACGCTCACCCCAAAATTAAACACCAAGATCCTCTAACTTGTTTGGATTGACTGATGAAGACATAAAGCTCTATGTTTTTTGA
GGTGGAGTGAGTGGTTTTTCTTCATTTTTAAATGGCCAAATGACAGCTTGACCCAGTTTGCTTTCCAATCAAAGGGCATTTATTTTGAAT
GTCTCTTTGTGGCGCAAGAGCCAACGCAAAAATGATGGCGGCTTACAATGGCGGTACATCTGCAGCAGCAGCAGGTCACCACCACCACCA
TCACCACCACCTTCCACACCTCCCTCCTCCTCACCTGCACCACCACCACCACCCTCAACACCATCTTCATCCGGGGTCGGCTGCCGCTGT
ACACCCTGTACAGCAGCACACCTCTTCGGCAGCTGCGGCAGCCGCAGCAGCGGCTGCAGCTGCAGCCATGTTAAACCCTGGGCAACAACA
GCCATATTTCCCATCACCGGCACCGGGGCAGGCTCCTGGACCAGCTGCAGCAGCCCCAGCTCAGGTACAGGCTGCCGCAGCTGCTACAGT
TAAGGCGCACCATCATCAGCACTCGCATCATCCACAGCAGCAGCTGGATATTGAGCCGGATAGACCTATTGGATATGGAGCCTTTGGTGT
TGTCTGGTTTGCTGTGAACTTTCAGACTGGCTTCAGTGGAAATGACATTGCCTTCCACTTCAACCCTCGGTTTGAAGATGGAGGGTACGT
GGTGTGCAACACGAGGCAGAACGGAAGCTGGGGGCCCGAGGAGAGGAAGACACACATGCCTTTCCAGAAGGGGATGCCCTTTGACCTCTG
CTTCCTGGTGCAGAGCTCAGATTTCAAGGTGATGGTGAACGGGATCCTCTTCGTGCAGTACTTCCACCGCGTGCCCTTCCACCGTGTGGA
CACCATCTCCGTCAATGGCTCTGTGCAGCTGTCCTACATCAGCTTCCAGACCCAGACAGTCATCCACACAGTGCAGAGCGCCCCTGGACA
GATGTTCTCTACTCCCGCCATCCCACCTATGATGTACCCCCACCCCGCCTATCCGATGCCTTTCATCACCACCATTCTGGGAGGGCTGTA
CCCATCCAAGTCCATCCTCCTGTCAGGCACTGTCCTGCCCAGTGCTCAGAGGTTCCACATCAACCTGTGCTCTGGGAACCACATCGCCTT
CCACCTGAACCCCCGTTTTGATGAGAATGCTGTGGTCCGCAACACCCAGATCGACAACTCCTGGGGGTCTGAGGAGCGAAGTCTGCCCCG
AAAAATGCCCTTCGTCCGTGGCCAGAGCTTCTCAGTGTGGATCTTGTGTGAAGCTCACTGCCTCAAGGTGGCCGTGGATGGTCAGCACCT
GTTTGAATACTACCATCGCCTGAGGAACCTGCCCACCATCAACAGACTGGAAGTGGGGGGCGACATCCAGCTGACCCATGTGCAGACATA
GGCGGCTTCCTGGCCCTGGGGCCGGGGGCTGGGGTGTGGGGCAGTCTGGGTCCTCTCATCATCCCCACTTCCCAGGCCCAGCCTTTCCAA
CCCTGCCTGGGATCTGGGCTTTAATGCAGAGGCCATGTCCTTGTCTGGTCCTGCTTCTGGCTACAGCCACCCTGGAACGGAGAAGGCAGC
TGACGGGGATTGCCTTCCTCAGCCGCAGCAGCACCTGGGGCTCCAGCTGCTGGAATCCTACCATCCCAGGAGGCAGGCACAGCCAGGGAG
AGGGGAGGAGTGGGCAGTGAAGATGAAGCCCCATGCTCAGTCCCCTCCCATCCCCCACGCAGCTCCACCCCAGTCCCAAGCCACCAGCTG
TCTGCTCCTGGTGGGAGGTGGCCTCCTCAGCCCCTCCTCTCTGACCTTTAACCTCACTCTCACCTTGCACCGTGCACCAACCCTTCACCC
CTCCTGGAAAGCAGGCCTGATGGCTTCCCACTGGCCTCCACCACCTGACCAGAGTGTTCTCTTCAGAGGACTGGCTCCTTTCCCAGTGTC

>59350_59350_2_NLK-LGALS9_NLK_chr17_26370357_ENST00000407008_LGALS9_chr17_25967598_ENST00000310394_length(amino acids)=420AA_BP=153
MSLCGARANAKMMAAYNGGTSAAAAGHHHHHHHHLPHLPPPHLHHHHHPQHHLHPGSAAAVHPVQQHTSSAAAAAAAAAAAAAMLNPGQQ
QPYFPSPAPGQAPGPAAAAPAQVQAAAAATVKAHHHQHSHHPQQQLDIEPDRPIGYGAFGVVWFAVNFQTGFSGNDIAFHFNPRFEDGGY
VVCNTRQNGSWGPEERKTHMPFQKGMPFDLCFLVQSSDFKVMVNGILFVQYFHRVPFHRVDTISVNGSVQLSYISFQTQTVIHTVQSAPG
QMFSTPAIPPMMYPHPAYPMPFITTILGGLYPSKSILLSGTVLPSAQRFHINLCSGNHIAFHLNPRFDENAVVRNTQIDNSWGSEERSLP

--------------------------------------------------------------
>59350_59350_3_NLK-LGALS9_NLK_chr17_26370357_ENST00000407008_LGALS9_chr17_25967598_ENST00000313648_length(transcript)=2305nt_BP=1176nt
CCCCGGCTCTCTTTCTCCTCTCTGTCCTGCTGTCGCCTCCTCTCCTCACTCCAGCCTCCTTCCCTGGCTTATTCTGCCCAGGAAAGTTTG
GAACCCCCGCCCCCCCTCCCCAATCAGGTCAACCTGACTAGGAGTAGGGGGAGATGTAGGAAGGCCTGAGAGTTCGGGGGGGGGGAAGCT
GGAAGCTGGTTTCCCAGAAAATTTCCCCCCATCTTCTCCATTTAGGGTGGTGGGAATTTTTTTTAATCCTGTTTTTGAGGAGGTGGTAGG
TGTTTAGAAAAGGATGTGGGAATGGAAGGGGTAGATGAGTCAACCCTCTTTCAAGATTCCAAGGGTGGTGTGTTACCTGATCCTTTTCGT
GTGTGGAGTTCAGGGGGTCGGGAGGTTTGGCCTTTATTCCCACATTCAAAGTTGGAACCTCCCCCAAATTAAGAATGGAGTTTTAGTACC
CACTTGTGGCAGGAATCCTGGGGGGAAGGGGTCCTTTTTTCCTTTTTCTTTTCTTTTTTCCCTTTTTTTTCCTTTTGGCAACCCACACCC
TTCCACACACGCTCACCCCAAAATTAAACACCAAGATCCTCTAACTTGTTTGGATTGACTGATGAAGACATAAAGCTCTATGTTTTTTGA
GGTGGAGTGAGTGGTTTTTCTTCATTTTTAAATGGCCAAATGACAGCTTGACCCAGTTTGCTTTCCAATCAAAGGGCATTTATTTTGAAT
GTCTCTTTGTGGCGCAAGAGCCAACGCAAAAATGATGGCGGCTTACAATGGCGGTACATCTGCAGCAGCAGCAGGTCACCACCACCACCA
TCACCACCACCTTCCACACCTCCCTCCTCCTCACCTGCACCACCACCACCACCCTCAACACCATCTTCATCCGGGGTCGGCTGCCGCTGT
ACACCCTGTACAGCAGCACACCTCTTCGGCAGCTGCGGCAGCCGCAGCAGCGGCTGCAGCTGCAGCCATGTTAAACCCTGGGCAACAACA
GCCATATTTCCCATCACCGGCACCGGGGCAGGCTCCTGGACCAGCTGCAGCAGCCCCAGCTCAGGTACAGGCTGCCGCAGCTGCTACAGT
TAAGGCGCACCATCATCAGCACTCGCATCATCCACAGCAGCAGCTGGATATTGAGCCGGATAGACCTATTGGATATGGAGCCTTTGGTGT
TGTCTGGTTTGCTGTGAACTTTCAGACTGGCTTCAGTGGAAATGACATTGCCTTCCACTTCAACCCTCGGTTTGAAGATGGAGGGTACGT
GGTGTGCAACACGAGGCAGAACGGAAGCTGGGGGCCCGAGGAGAGGAAGACACACATGCCTTTCCAGAAGGGGATGCCCTTTGACCTCTG
CTTCCTGGTGCAGAGCTCAGATTTCAAGGTGATGGTGAACGGGATCCTCTTCGTGCAGTACTTCCACCGCGTGCCCTTCCACCGTGTGGA
CACCATCTCCGTCAATGGCTCTGTGCAGCTGTCCTACATCAGCTTCCAGCCTCCCGGCGTGTGGCCTGCCAACCCGGCTCCCATTACCCA
GACAGTCATCCACACAGTGCAGAGCGCCCCTGGACAGATGTTCTCTACTCCCGCCATCCCACCTATGATGTACCCCCACCCCGCCTATCC
GATGCCTTTCATCACCACCATTCTGGGAGGGCTGTACCCATCCAAGTCCATCCTCCTGTCAGGCACTGTCCTGCCCAGTGCTCAGAGGTG
TGGATCTTGTGTGAAGCTCACTGCCTCAAGGTGGCCGTGGATGGTCAGCACCTGTTTGAATACTACCATCGCCTGAGGAACCTGCCCACC
ATCAACAGACTGGAAGTGGGGGGCGACATCCAGCTGACCCATGTGCAGACATAGGCGGCTTCCTGGCCCTGGGGCCGGGGGCTGGGGTGT
GGGGCAGTCTGGGTCCTCTCATCATCCCCACTTCCCAGGCCCAGCCTTTCCAACCCTGCCTGGGATCTGGGCTTTAATGCAGAGGCCATG
TCCTTGTCTGGTCCTGCTTCTGGCTACAGCCACCCTGGAACGGAGAAGGCAGCTGACGGGGATTGCCTTCCTCAGCCGCAGCAGCACCTG
GGGCTCCAGCTGCTGGAATCCTACCATCCCAGGAGGCAGGCACAGCCAGGGAGAGGGGAGGAGTGGGCAGTGAAGATGAAGCCCCATGCT
CAGTCCCCTCCCATCCCCCACGCAGCTCCACCCCAGTCCCAAGCCACCAGCTGTCTGCTCCTGGTGGGAGGTGGCCTCCTCAGCCCCTCC

>59350_59350_3_NLK-LGALS9_NLK_chr17_26370357_ENST00000407008_LGALS9_chr17_25967598_ENST00000313648_length(amino acids)=355AA_BP=153
MSLCGARANAKMMAAYNGGTSAAAAGHHHHHHHHLPHLPPPHLHHHHHPQHHLHPGSAAAVHPVQQHTSSAAAAAAAAAAAAAMLNPGQQ
QPYFPSPAPGQAPGPAAAAPAQVQAAAAATVKAHHHQHSHHPQQQLDIEPDRPIGYGAFGVVWFAVNFQTGFSGNDIAFHFNPRFEDGGY
VVCNTRQNGSWGPEERKTHMPFQKGMPFDLCFLVQSSDFKVMVNGILFVQYFHRVPFHRVDTISVNGSVQLSYISFQPPGVWPANPAPIT

--------------------------------------------------------------
>59350_59350_4_NLK-LGALS9_NLK_chr17_26370357_ENST00000407008_LGALS9_chr17_25967598_ENST00000395473_length(transcript)=2691nt_BP=1176nt
CCCCGGCTCTCTTTCTCCTCTCTGTCCTGCTGTCGCCTCCTCTCCTCACTCCAGCCTCCTTCCCTGGCTTATTCTGCCCAGGAAAGTTTG
GAACCCCCGCCCCCCCTCCCCAATCAGGTCAACCTGACTAGGAGTAGGGGGAGATGTAGGAAGGCCTGAGAGTTCGGGGGGGGGGAAGCT
GGAAGCTGGTTTCCCAGAAAATTTCCCCCCATCTTCTCCATTTAGGGTGGTGGGAATTTTTTTTAATCCTGTTTTTGAGGAGGTGGTAGG
TGTTTAGAAAAGGATGTGGGAATGGAAGGGGTAGATGAGTCAACCCTCTTTCAAGATTCCAAGGGTGGTGTGTTACCTGATCCTTTTCGT
GTGTGGAGTTCAGGGGGTCGGGAGGTTTGGCCTTTATTCCCACATTCAAAGTTGGAACCTCCCCCAAATTAAGAATGGAGTTTTAGTACC
CACTTGTGGCAGGAATCCTGGGGGGAAGGGGTCCTTTTTTCCTTTTTCTTTTCTTTTTTCCCTTTTTTTTCCTTTTGGCAACCCACACCC
TTCCACACACGCTCACCCCAAAATTAAACACCAAGATCCTCTAACTTGTTTGGATTGACTGATGAAGACATAAAGCTCTATGTTTTTTGA
GGTGGAGTGAGTGGTTTTTCTTCATTTTTAAATGGCCAAATGACAGCTTGACCCAGTTTGCTTTCCAATCAAAGGGCATTTATTTTGAAT
GTCTCTTTGTGGCGCAAGAGCCAACGCAAAAATGATGGCGGCTTACAATGGCGGTACATCTGCAGCAGCAGCAGGTCACCACCACCACCA
TCACCACCACCTTCCACACCTCCCTCCTCCTCACCTGCACCACCACCACCACCCTCAACACCATCTTCATCCGGGGTCGGCTGCCGCTGT
ACACCCTGTACAGCAGCACACCTCTTCGGCAGCTGCGGCAGCCGCAGCAGCGGCTGCAGCTGCAGCCATGTTAAACCCTGGGCAACAACA
GCCATATTTCCCATCACCGGCACCGGGGCAGGCTCCTGGACCAGCTGCAGCAGCCCCAGCTCAGGTACAGGCTGCCGCAGCTGCTACAGT
TAAGGCGCACCATCATCAGCACTCGCATCATCCACAGCAGCAGCTGGATATTGAGCCGGATAGACCTATTGGATATGGAGCCTTTGGTGT
TGTCTGGTTTGCTGTGAACTTTCAGACTGGCTTCAGTGGAAATGACATTGCCTTCCACTTCAACCCTCGGTTTGAAGATGGAGGGTACGT
GGTGTGCAACACGAGGCAGAACGGAAGCTGGGGGCCCGAGGAGAGGAAGACACACATGCCTTTCCAGAAGGGGATGCCCTTTGACCTCTG
CTTCCTGGTGCAGAGCTCAGATTTCAAGGTGATGGTGAACGGGATCCTCTTCGTGCAGTACTTCCACCGCGTGCCCTTCCACCGTGTGGA
CACCATCTCCGTCAATGGCTCTGTGCAGCTGTCCTACATCAGCTTCCAGAACCCCCGCACAGTCCCTGTTCAGCCTGCCTTCTCCACGGT
GCCGTTCTCCCAGCCTGTCTGTTTCCCACCCAGGCCCAGGGGGCGCAGACAAAAACCTCCCGGCGTGTGGCCTGCCAACCCGGCTCCCAT
TACCCAGACAGTCATCCACACAGTGCAGAGCGCCCCTGGACAGATGTTCTCTACTCCCGCCATCCCACCTATGATGTACCCCCACCCCGC
CTATCCGATGCCTTTCATCACCACCATTCTGGGAGGGCTGTACCCATCCAAGTCCATCCTCCTGTCAGGCACTGTCCTGCCCAGTGCTCA
GAGGTTCCACATCAACCTGTGCTCTGGGAACCACATCGCCTTCCACCTGAACCCCCGTTTTGATGAGAATGCTGTGGTCCGCAACACCCA
GATCGACAACTCCTGGGGGTCTGAGGAGCGAAGTCTGCCCCGAAAAATGCCCTTCGTCCGTGGCCAGAGCTTCTCAGTGTGGATCTTGTG
TGAAGCTCACTGCCTCAAGGTGGCCGTGGATGGTCAGCACCTGTTTGAATACTACCATCGCCTGAGGAACCTGCCCACCATCAACAGACT
GGAAGTGGGGGGCGACATCCAGCTGACCCATGTGCAGACATAGGCGGCTTCCTGGCCCTGGGGCCGGGGGCTGGGGTGTGGGGCAGTCTG
GGTCCTCTCATCATCCCCACTTCCCAGGCCCAGCCTTTCCAACCCTGCCTGGGATCTGGGCTTTAATGCAGAGGCCATGTCCTTGTCTGG
TCCTGCTTCTGGCTACAGCCACCCTGGAACGGAGAAGGCAGCTGACGGGGATTGCCTTCCTCAGCCGCAGCAGCACCTGGGGCTCCAGCT
GCTGGAATCCTACCATCCCAGGAGGCAGGCACAGCCAGGGAGAGGGGAGGAGTGGGCAGTGAAGATGAAGCCCCATGCTCAGTCCCCTCC
CATCCCCCACGCAGCTCCACCCCAGTCCCAAGCCACCAGCTGTCTGCTCCTGGTGGGAGGTGGCCTCCTCAGCCCCTCCTCTCTGACCTT
TAACCTCACTCTCACCTTGCACCGTGCACCAACCCTTCACCCCTCCTGGAAAGCAGGCCTGATGGCTTCCCACTGGCCTCCACCACCTGA

>59350_59350_4_NLK-LGALS9_NLK_chr17_26370357_ENST00000407008_LGALS9_chr17_25967598_ENST00000395473_length(amino acids)=464AA_BP=153
MSLCGARANAKMMAAYNGGTSAAAAGHHHHHHHHLPHLPPPHLHHHHHPQHHLHPGSAAAVHPVQQHTSSAAAAAAAAAAAAAMLNPGQQ
QPYFPSPAPGQAPGPAAAAPAQVQAAAAATVKAHHHQHSHHPQQQLDIEPDRPIGYGAFGVVWFAVNFQTGFSGNDIAFHFNPRFEDGGY
VVCNTRQNGSWGPEERKTHMPFQKGMPFDLCFLVQSSDFKVMVNGILFVQYFHRVPFHRVDTISVNGSVQLSYISFQNPRTVPVQPAFST
VPFSQPVCFPPRPRGRRQKPPGVWPANPAPITQTVIHTVQSAPGQMFSTPAIPPMMYPHPAYPMPFITTILGGLYPSKSILLSGTVLPSA
QRFHINLCSGNHIAFHLNPRFDENAVVRNTQIDNSWGSEERSLPRKMPFVRGQSFSVWILCEAHCLKVAVDGQHLFEYYHRLRNLPTINR

--------------------------------------------------------------
>59350_59350_5_NLK-LGALS9_NLK_chr17_26370357_ENST00000582037_LGALS9_chr17_25967598_ENST00000302228_length(transcript)=1912nt_BP=493nt
CAGTTTGCTTTCCAATCAAAGGGCATTTATTTTGAATGTCTCTTTGTGGCGCAAGAGCCAACGCAAAAATGATGGCGGCTTACAATGGCG
GTACATCTGCAGCAGCAGCAGGTCACCACCACCACCATCACCACCACCTTCCACACCTCCCTCCTCCTCACCTGCACCACCACCACCACC
CTCAACACCATCTTCATCCGGGGTCGGCTGCCGCTGTACACCCTGTACAGCAGCACACCTCTTCGGCAGCTGCGGCAGCCGCAGCAGCGG
CTGCAGCTGCAGCCATGTTAAACCCTGGGCAACAACAGCCATATTTCCCATCACCGGCACCGGGGCAGGCTCCTGGACCAGCTGCAGCAG
CCCCAGCTCAGGTACAGGCTGCCGCAGCTGCTACAGTTAAGGCGCACCATCATCAGCACTCGCATCATCCACAGCAGCAGCTGGATATTG
AGCCGGATAGACCTATTGGATATGGAGCCTTTGGTGTTGTCTGGTTTGCTGTGAACTTTCAGACTGGCTTCAGTGGAAATGACATTGCCT
TCCACTTCAACCCTCGGTTTGAAGATGGAGGGTACGTGGTGTGCAACACGAGGCAGAACGGAAGCTGGGGGCCCGAGGAGAGGAAGACAC
ACATGCCTTTCCAGAAGGGGATGCCCTTTGACCTCTGCTTCCTGGTGCAGAGCTCAGATTTCAAGGTGATGGTGAACGGGATCCTCTTCG
TGCAGTACTTCCACCGCGTGCCCTTCCACCGTGTGGACACCATCTCCGTCAATGGCTCTGTGCAGCTGTCCTACATCAGCTTCCAGCCTC
CCGGCGTGTGGCCTGCCAACCCGGCTCCCATTACCCAGACAGTCATCCACACAGTGCAGAGCGCCCCTGGACAGATGTTCTCTACTCCCG
CCATCCCACCTATGATGTACCCCCACCCCGCCTATCCGATGCCTTTCATCACCACCATTCTGGGAGGGCTGTACCCATCCAAGTCCATCC
TCCTGTCAGGCACTGTCCTGCCCAGTGCTCAGAGGTTCCACATCAACCTGTGCTCTGGGAACCACATCGCCTTCCACCTGAACCCCCGTT
TTGATGAGAATGCTGTGGTCCGCAACACCCAGATCGACAACTCCTGGGGGTCTGAGGAGCGAAGTCTGCCCCGAAAAATGCCCTTCGTCC
GTGGCCAGAGCTTCTCAGTGTGGATCTTGTGTGAAGCTCACTGCCTCAAGGTGGCCGTGGATGGTCAGCACCTGTTTGAATACTACCATC
GCCTGAGGAACCTGCCCACCATCAACAGACTGGAAGTGGGGGGCGACATCCAGCTGACCCATGTGCAGACATAGGCGGCTTCCTGGCCCT
GGGGCCGGGGGCTGGGGTGTGGGGCAGTCTGGGTCCTCTCATCATCCCCACTTCCCAGGCCCAGCCTTTCCAACCCTGCCTGGGATCTGG
GCTTTAATGCAGAGGCCATGTCCTTGTCTGGTCCTGCTTCTGGCTACAGCCACCCTGGAACGGAGAAGGCAGCTGACGGGGATTGCCTTC
CTCAGCCGCAGCAGCACCTGGGGCTCCAGCTGCTGGAATCCTACCATCCCAGGAGGCAGGCACAGCCAGGGAGAGGGGAGGAGTGGGCAG
TGAAGATGAAGCCCCATGCTCAGTCCCCTCCCATCCCCCACGCAGCTCCACCCCAGTCCCAAGCCACCAGCTGTCTGCTCCTGGTGGGAG
GTGGCCTCCTCAGCCCCTCCTCTCTGACCTTTAACCTCACTCTCACCTTGCACCGTGCACCAACCCTTCACCCCTCCTGGAAAGCAGGCC
TGATGGCTTCCCACTGGCCTCCACCACCTGACCAGAGTGTTCTCTTCAGAGGACTGGCTCCTTTCCCAGTGTCCTTAAAATAAAGAAATG

>59350_59350_5_NLK-LGALS9_NLK_chr17_26370357_ENST00000582037_LGALS9_chr17_25967598_ENST00000302228_length(amino acids)=432AA_BP=153
MSLCGARANAKMMAAYNGGTSAAAAGHHHHHHHHLPHLPPPHLHHHHHPQHHLHPGSAAAVHPVQQHTSSAAAAAAAAAAAAAMLNPGQQ
QPYFPSPAPGQAPGPAAAAPAQVQAAAAATVKAHHHQHSHHPQQQLDIEPDRPIGYGAFGVVWFAVNFQTGFSGNDIAFHFNPRFEDGGY
VVCNTRQNGSWGPEERKTHMPFQKGMPFDLCFLVQSSDFKVMVNGILFVQYFHRVPFHRVDTISVNGSVQLSYISFQPPGVWPANPAPIT
QTVIHTVQSAPGQMFSTPAIPPMMYPHPAYPMPFITTILGGLYPSKSILLSGTVLPSAQRFHINLCSGNHIAFHLNPRFDENAVVRNTQI

--------------------------------------------------------------
>59350_59350_6_NLK-LGALS9_NLK_chr17_26370357_ENST00000582037_LGALS9_chr17_25967598_ENST00000310394_length(transcript)=1869nt_BP=493nt
CAGTTTGCTTTCCAATCAAAGGGCATTTATTTTGAATGTCTCTTTGTGGCGCAAGAGCCAACGCAAAAATGATGGCGGCTTACAATGGCG
GTACATCTGCAGCAGCAGCAGGTCACCACCACCACCATCACCACCACCTTCCACACCTCCCTCCTCCTCACCTGCACCACCACCACCACC
CTCAACACCATCTTCATCCGGGGTCGGCTGCCGCTGTACACCCTGTACAGCAGCACACCTCTTCGGCAGCTGCGGCAGCCGCAGCAGCGG
CTGCAGCTGCAGCCATGTTAAACCCTGGGCAACAACAGCCATATTTCCCATCACCGGCACCGGGGCAGGCTCCTGGACCAGCTGCAGCAG
CCCCAGCTCAGGTACAGGCTGCCGCAGCTGCTACAGTTAAGGCGCACCATCATCAGCACTCGCATCATCCACAGCAGCAGCTGGATATTG
AGCCGGATAGACCTATTGGATATGGAGCCTTTGGTGTTGTCTGGTTTGCTGTGAACTTTCAGACTGGCTTCAGTGGAAATGACATTGCCT
TCCACTTCAACCCTCGGTTTGAAGATGGAGGGTACGTGGTGTGCAACACGAGGCAGAACGGAAGCTGGGGGCCCGAGGAGAGGAAGACAC
ACATGCCTTTCCAGAAGGGGATGCCCTTTGACCTCTGCTTCCTGGTGCAGAGCTCAGATTTCAAGGTGATGGTGAACGGGATCCTCTTCG
TGCAGTACTTCCACCGCGTGCCCTTCCACCGTGTGGACACCATCTCCGTCAATGGCTCTGTGCAGCTGTCCTACATCAGCTTCCAGACCC
AGACAGTCATCCACACAGTGCAGAGCGCCCCTGGACAGATGTTCTCTACTCCCGCCATCCCACCTATGATGTACCCCCACCCCGCCTATC
CGATGCCTTTCATCACCACCATTCTGGGAGGGCTGTACCCATCCAAGTCCATCCTCCTGTCAGGCACTGTCCTGCCCAGTGCTCAGAGGT
TCCACATCAACCTGTGCTCTGGGAACCACATCGCCTTCCACCTGAACCCCCGTTTTGATGAGAATGCTGTGGTCCGCAACACCCAGATCG
ACAACTCCTGGGGGTCTGAGGAGCGAAGTCTGCCCCGAAAAATGCCCTTCGTCCGTGGCCAGAGCTTCTCAGTGTGGATCTTGTGTGAAG
CTCACTGCCTCAAGGTGGCCGTGGATGGTCAGCACCTGTTTGAATACTACCATCGCCTGAGGAACCTGCCCACCATCAACAGACTGGAAG
TGGGGGGCGACATCCAGCTGACCCATGTGCAGACATAGGCGGCTTCCTGGCCCTGGGGCCGGGGGCTGGGGTGTGGGGCAGTCTGGGTCC
TCTCATCATCCCCACTTCCCAGGCCCAGCCTTTCCAACCCTGCCTGGGATCTGGGCTTTAATGCAGAGGCCATGTCCTTGTCTGGTCCTG
CTTCTGGCTACAGCCACCCTGGAACGGAGAAGGCAGCTGACGGGGATTGCCTTCCTCAGCCGCAGCAGCACCTGGGGCTCCAGCTGCTGG
AATCCTACCATCCCAGGAGGCAGGCACAGCCAGGGAGAGGGGAGGAGTGGGCAGTGAAGATGAAGCCCCATGCTCAGTCCCCTCCCATCC
CCCACGCAGCTCCACCCCAGTCCCAAGCCACCAGCTGTCTGCTCCTGGTGGGAGGTGGCCTCCTCAGCCCCTCCTCTCTGACCTTTAACC
TCACTCTCACCTTGCACCGTGCACCAACCCTTCACCCCTCCTGGAAAGCAGGCCTGATGGCTTCCCACTGGCCTCCACCACCTGACCAGA

>59350_59350_6_NLK-LGALS9_NLK_chr17_26370357_ENST00000582037_LGALS9_chr17_25967598_ENST00000310394_length(amino acids)=420AA_BP=153
MSLCGARANAKMMAAYNGGTSAAAAGHHHHHHHHLPHLPPPHLHHHHHPQHHLHPGSAAAVHPVQQHTSSAAAAAAAAAAAAAMLNPGQQ
QPYFPSPAPGQAPGPAAAAPAQVQAAAAATVKAHHHQHSHHPQQQLDIEPDRPIGYGAFGVVWFAVNFQTGFSGNDIAFHFNPRFEDGGY
VVCNTRQNGSWGPEERKTHMPFQKGMPFDLCFLVQSSDFKVMVNGILFVQYFHRVPFHRVDTISVNGSVQLSYISFQTQTVIHTVQSAPG
QMFSTPAIPPMMYPHPAYPMPFITTILGGLYPSKSILLSGTVLPSAQRFHINLCSGNHIAFHLNPRFDENAVVRNTQIDNSWGSEERSLP

--------------------------------------------------------------
>59350_59350_7_NLK-LGALS9_NLK_chr17_26370357_ENST00000582037_LGALS9_chr17_25967598_ENST00000313648_length(transcript)=1622nt_BP=493nt
CAGTTTGCTTTCCAATCAAAGGGCATTTATTTTGAATGTCTCTTTGTGGCGCAAGAGCCAACGCAAAAATGATGGCGGCTTACAATGGCG
GTACATCTGCAGCAGCAGCAGGTCACCACCACCACCATCACCACCACCTTCCACACCTCCCTCCTCCTCACCTGCACCACCACCACCACC
CTCAACACCATCTTCATCCGGGGTCGGCTGCCGCTGTACACCCTGTACAGCAGCACACCTCTTCGGCAGCTGCGGCAGCCGCAGCAGCGG
CTGCAGCTGCAGCCATGTTAAACCCTGGGCAACAACAGCCATATTTCCCATCACCGGCACCGGGGCAGGCTCCTGGACCAGCTGCAGCAG
CCCCAGCTCAGGTACAGGCTGCCGCAGCTGCTACAGTTAAGGCGCACCATCATCAGCACTCGCATCATCCACAGCAGCAGCTGGATATTG
AGCCGGATAGACCTATTGGATATGGAGCCTTTGGTGTTGTCTGGTTTGCTGTGAACTTTCAGACTGGCTTCAGTGGAAATGACATTGCCT
TCCACTTCAACCCTCGGTTTGAAGATGGAGGGTACGTGGTGTGCAACACGAGGCAGAACGGAAGCTGGGGGCCCGAGGAGAGGAAGACAC
ACATGCCTTTCCAGAAGGGGATGCCCTTTGACCTCTGCTTCCTGGTGCAGAGCTCAGATTTCAAGGTGATGGTGAACGGGATCCTCTTCG
TGCAGTACTTCCACCGCGTGCCCTTCCACCGTGTGGACACCATCTCCGTCAATGGCTCTGTGCAGCTGTCCTACATCAGCTTCCAGCCTC
CCGGCGTGTGGCCTGCCAACCCGGCTCCCATTACCCAGACAGTCATCCACACAGTGCAGAGCGCCCCTGGACAGATGTTCTCTACTCCCG
CCATCCCACCTATGATGTACCCCCACCCCGCCTATCCGATGCCTTTCATCACCACCATTCTGGGAGGGCTGTACCCATCCAAGTCCATCC
TCCTGTCAGGCACTGTCCTGCCCAGTGCTCAGAGGTGTGGATCTTGTGTGAAGCTCACTGCCTCAAGGTGGCCGTGGATGGTCAGCACCT
GTTTGAATACTACCATCGCCTGAGGAACCTGCCCACCATCAACAGACTGGAAGTGGGGGGCGACATCCAGCTGACCCATGTGCAGACATA
GGCGGCTTCCTGGCCCTGGGGCCGGGGGCTGGGGTGTGGGGCAGTCTGGGTCCTCTCATCATCCCCACTTCCCAGGCCCAGCCTTTCCAA
CCCTGCCTGGGATCTGGGCTTTAATGCAGAGGCCATGTCCTTGTCTGGTCCTGCTTCTGGCTACAGCCACCCTGGAACGGAGAAGGCAGC
TGACGGGGATTGCCTTCCTCAGCCGCAGCAGCACCTGGGGCTCCAGCTGCTGGAATCCTACCATCCCAGGAGGCAGGCACAGCCAGGGAG
AGGGGAGGAGTGGGCAGTGAAGATGAAGCCCCATGCTCAGTCCCCTCCCATCCCCCACGCAGCTCCACCCCAGTCCCAAGCCACCAGCTG
TCTGCTCCTGGTGGGAGGTGGCCTCCTCAGCCCCTCCTCTCTGACCTTTAACCTCACTCTCACCTTGCACCGTGCACCAACCCTTCACCC

>59350_59350_7_NLK-LGALS9_NLK_chr17_26370357_ENST00000582037_LGALS9_chr17_25967598_ENST00000313648_length(amino acids)=355AA_BP=153
MSLCGARANAKMMAAYNGGTSAAAAGHHHHHHHHLPHLPPPHLHHHHHPQHHLHPGSAAAVHPVQQHTSSAAAAAAAAAAAAAMLNPGQQ
QPYFPSPAPGQAPGPAAAAPAQVQAAAAATVKAHHHQHSHHPQQQLDIEPDRPIGYGAFGVVWFAVNFQTGFSGNDIAFHFNPRFEDGGY
VVCNTRQNGSWGPEERKTHMPFQKGMPFDLCFLVQSSDFKVMVNGILFVQYFHRVPFHRVDTISVNGSVQLSYISFQPPGVWPANPAPIT

--------------------------------------------------------------
>59350_59350_8_NLK-LGALS9_NLK_chr17_26370357_ENST00000582037_LGALS9_chr17_25967598_ENST00000395473_length(transcript)=2008nt_BP=493nt
CAGTTTGCTTTCCAATCAAAGGGCATTTATTTTGAATGTCTCTTTGTGGCGCAAGAGCCAACGCAAAAATGATGGCGGCTTACAATGGCG
GTACATCTGCAGCAGCAGCAGGTCACCACCACCACCATCACCACCACCTTCCACACCTCCCTCCTCCTCACCTGCACCACCACCACCACC
CTCAACACCATCTTCATCCGGGGTCGGCTGCCGCTGTACACCCTGTACAGCAGCACACCTCTTCGGCAGCTGCGGCAGCCGCAGCAGCGG
CTGCAGCTGCAGCCATGTTAAACCCTGGGCAACAACAGCCATATTTCCCATCACCGGCACCGGGGCAGGCTCCTGGACCAGCTGCAGCAG
CCCCAGCTCAGGTACAGGCTGCCGCAGCTGCTACAGTTAAGGCGCACCATCATCAGCACTCGCATCATCCACAGCAGCAGCTGGATATTG
AGCCGGATAGACCTATTGGATATGGAGCCTTTGGTGTTGTCTGGTTTGCTGTGAACTTTCAGACTGGCTTCAGTGGAAATGACATTGCCT
TCCACTTCAACCCTCGGTTTGAAGATGGAGGGTACGTGGTGTGCAACACGAGGCAGAACGGAAGCTGGGGGCCCGAGGAGAGGAAGACAC
ACATGCCTTTCCAGAAGGGGATGCCCTTTGACCTCTGCTTCCTGGTGCAGAGCTCAGATTTCAAGGTGATGGTGAACGGGATCCTCTTCG
TGCAGTACTTCCACCGCGTGCCCTTCCACCGTGTGGACACCATCTCCGTCAATGGCTCTGTGCAGCTGTCCTACATCAGCTTCCAGAACC
CCCGCACAGTCCCTGTTCAGCCTGCCTTCTCCACGGTGCCGTTCTCCCAGCCTGTCTGTTTCCCACCCAGGCCCAGGGGGCGCAGACAAA
AACCTCCCGGCGTGTGGCCTGCCAACCCGGCTCCCATTACCCAGACAGTCATCCACACAGTGCAGAGCGCCCCTGGACAGATGTTCTCTA
CTCCCGCCATCCCACCTATGATGTACCCCCACCCCGCCTATCCGATGCCTTTCATCACCACCATTCTGGGAGGGCTGTACCCATCCAAGT
CCATCCTCCTGTCAGGCACTGTCCTGCCCAGTGCTCAGAGGTTCCACATCAACCTGTGCTCTGGGAACCACATCGCCTTCCACCTGAACC
CCCGTTTTGATGAGAATGCTGTGGTCCGCAACACCCAGATCGACAACTCCTGGGGGTCTGAGGAGCGAAGTCTGCCCCGAAAAATGCCCT
TCGTCCGTGGCCAGAGCTTCTCAGTGTGGATCTTGTGTGAAGCTCACTGCCTCAAGGTGGCCGTGGATGGTCAGCACCTGTTTGAATACT
ACCATCGCCTGAGGAACCTGCCCACCATCAACAGACTGGAAGTGGGGGGCGACATCCAGCTGACCCATGTGCAGACATAGGCGGCTTCCT
GGCCCTGGGGCCGGGGGCTGGGGTGTGGGGCAGTCTGGGTCCTCTCATCATCCCCACTTCCCAGGCCCAGCCTTTCCAACCCTGCCTGGG
ATCTGGGCTTTAATGCAGAGGCCATGTCCTTGTCTGGTCCTGCTTCTGGCTACAGCCACCCTGGAACGGAGAAGGCAGCTGACGGGGATT
GCCTTCCTCAGCCGCAGCAGCACCTGGGGCTCCAGCTGCTGGAATCCTACCATCCCAGGAGGCAGGCACAGCCAGGGAGAGGGGAGGAGT
GGGCAGTGAAGATGAAGCCCCATGCTCAGTCCCCTCCCATCCCCCACGCAGCTCCACCCCAGTCCCAAGCCACCAGCTGTCTGCTCCTGG
TGGGAGGTGGCCTCCTCAGCCCCTCCTCTCTGACCTTTAACCTCACTCTCACCTTGCACCGTGCACCAACCCTTCACCCCTCCTGGAAAG
CAGGCCTGATGGCTTCCCACTGGCCTCCACCACCTGACCAGAGTGTTCTCTTCAGAGGACTGGCTCCTTTCCCAGTGTCCTTAAAATAAA

>59350_59350_8_NLK-LGALS9_NLK_chr17_26370357_ENST00000582037_LGALS9_chr17_25967598_ENST00000395473_length(amino acids)=464AA_BP=153
MSLCGARANAKMMAAYNGGTSAAAAGHHHHHHHHLPHLPPPHLHHHHHPQHHLHPGSAAAVHPVQQHTSSAAAAAAAAAAAAAMLNPGQQ
QPYFPSPAPGQAPGPAAAAPAQVQAAAAATVKAHHHQHSHHPQQQLDIEPDRPIGYGAFGVVWFAVNFQTGFSGNDIAFHFNPRFEDGGY
VVCNTRQNGSWGPEERKTHMPFQKGMPFDLCFLVQSSDFKVMVNGILFVQYFHRVPFHRVDTISVNGSVQLSYISFQNPRTVPVQPAFST
VPFSQPVCFPPRPRGRRQKPPGVWPANPAPITQTVIHTVQSAPGQMFSTPAIPPMMYPHPAYPMPFITTILGGLYPSKSILLSGTVLPSA
QRFHINLCSGNHIAFHLNPRFDENAVVRNTQIDNSWGSEERSLPRKMPFVRGQSFSVWILCEAHCLKVAVDGQHLFEYYHRLRNLPTINR

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Fusion Gene PPI Analysis for NLK-LGALS9


check button Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in

ChiPPI page.


check button Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160)
HgeneHgene's interactorsTgeneTgene's interactors


check button - Retained PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenStill interaction with


check button - Lost PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


check button - Retained PPIs, but lost function due to frame-shift fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


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Related Drugs for NLK-LGALS9


check button Drugs targeting genes involved in this fusion gene.
(DrugBank Version 5.1.8 2021-05-08)
PartnerGeneUniProtAccDrugBank IDDrug nameDrug activityDrug typeDrug status

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Related Diseases for NLK-LGALS9


check button Diseases associated with fusion partners.
(DisGeNet 4.0)
PartnerGeneDisease IDDisease name# pubmedsSource