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Center for Computational Systems Medicine
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Fusion Gene Summary

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Fusion Gene ORF analysis

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Fusion Genomic Features

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Fusion Protein Features

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Fusion Gene Sequence

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Fusion Gene PPI analysis

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Related Drugs

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Related Diseases

Fusion gene:NOL8-FXN (FusionGDB2 ID:59570)

Fusion Gene Summary for NOL8-FXN

check button Fusion gene summary
Fusion gene informationFusion gene name: NOL8-FXN
Fusion gene ID: 59570
HgeneTgene
Gene symbol

NOL8

FXN

Gene ID

55035

2395

Gene namenucleolar protein 8frataxin
SynonymsC9orf34|NOP132|bA62C3.3|bA62C3.4CyaY|FA|FARR|FRDA|X25
Cytomap

9q22.31

9q21.11

Type of geneprotein-codingprotein-coding
Descriptionnucleolar protein 8nucleolar protein Nop132frataxin, mitochondrialFriedreich ataxia protein
Modification date2020031320200315
UniProtAcc

Q76FK4

Q16595

Ensembl transtripts involved in fusion geneENST00000358855, ENST00000442668, 
ENST00000535387, ENST00000542053, 
ENST00000545558, ENST00000543985, 
ENST00000498653, ENST00000377270, 
ENST00000396364, ENST00000396366, 
Fusion gene scores* DoF score2 X 2 X 2=88 X 8 X 7=448
# samples 210
** MAII scorelog2(2/8*10)=1.32192809488736log2(10/448*10)=-2.16349873228288
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0
Context

PubMed: NOL8 [Title/Abstract] AND FXN [Title/Abstract] AND fusion [Title/Abstract]

Most frequent breakpointNOL8(95076549)-FXN(71661301), # samples:3
Anticipated loss of major functional domain due to fusion event.NOL8-FXN seems lost the major protein functional domain in Hgene partner, which is a essential gene due to the frame-shifted ORF.
NOL8-FXN seems lost the major protein functional domain in Tgene partner, which is a cell metabolism gene due to the frame-shifted ORF.
NOL8-FXN seems lost the major protein functional domain in Tgene partner, which is a tumor suppressor due to the frame-shifted ORF.
* DoF score (Degree of Frequency) = # partners X # break points X # cancer types
** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)

check button Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez
PartnerGeneGO IDGO termPubMed ID
TgeneFXN

GO:0010722

regulation of ferrochelatase activity

15123683

TgeneFXN

GO:0016226

iron-sulfur cluster assembly

29491838

TgeneFXN

GO:0016540

protein autoprocessing

12785837

TgeneFXN

GO:0018283

iron incorporation into metallo-sulfur cluster

12785837

TgeneFXN

GO:0051349

positive regulation of lyase activity

20053667

TgeneFXN

GO:0070301

cellular response to hydrogen peroxide

15641778


check buttonFusion gene breakpoints across NOL8 (5'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check buttonFusion gene breakpoints across FXN (3'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check button Fusion gene information from two resources (ChiTars 5.0 and ChimerDB 4.0)
* All genome coordinats were lifted-over on hg19.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
SourceDiseaseSampleHgeneHchrHbpHstrandTgeneTchrTbpTstrand
ChimerDB4TGCTTCGA-2G-AAM4-01ANOL8chr9

95076549

-FXNchr9

71661301

+
ChimerDB4TGCTTCGA-2G-AAM4NOL8chr9

95076549

-FXNchr9

71661301

+


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Fusion Gene ORF analysis for NOL8-FXN

check button Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
ORFHenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrand
5CDS-5UTRENST00000358855ENST00000498653NOL8chr9

95076549

-FXNchr9

71661301

+
5CDS-5UTRENST00000442668ENST00000498653NOL8chr9

95076549

-FXNchr9

71661301

+
5CDS-5UTRENST00000535387ENST00000498653NOL8chr9

95076549

-FXNchr9

71661301

+
5CDS-5UTRENST00000542053ENST00000498653NOL8chr9

95076549

-FXNchr9

71661301

+
5CDS-5UTRENST00000545558ENST00000498653NOL8chr9

95076549

-FXNchr9

71661301

+
Frame-shiftENST00000358855ENST00000377270NOL8chr9

95076549

-FXNchr9

71661301

+
Frame-shiftENST00000358855ENST00000396364NOL8chr9

95076549

-FXNchr9

71661301

+
Frame-shiftENST00000358855ENST00000396366NOL8chr9

95076549

-FXNchr9

71661301

+
Frame-shiftENST00000442668ENST00000377270NOL8chr9

95076549

-FXNchr9

71661301

+
Frame-shiftENST00000442668ENST00000396364NOL8chr9

95076549

-FXNchr9

71661301

+
Frame-shiftENST00000442668ENST00000396366NOL8chr9

95076549

-FXNchr9

71661301

+
Frame-shiftENST00000542053ENST00000377270NOL8chr9

95076549

-FXNchr9

71661301

+
Frame-shiftENST00000542053ENST00000396364NOL8chr9

95076549

-FXNchr9

71661301

+
Frame-shiftENST00000542053ENST00000396366NOL8chr9

95076549

-FXNchr9

71661301

+
In-frameENST00000535387ENST00000377270NOL8chr9

95076549

-FXNchr9

71661301

+
In-frameENST00000535387ENST00000396364NOL8chr9

95076549

-FXNchr9

71661301

+
In-frameENST00000535387ENST00000396366NOL8chr9

95076549

-FXNchr9

71661301

+
In-frameENST00000545558ENST00000377270NOL8chr9

95076549

-FXNchr9

71661301

+
In-frameENST00000545558ENST00000396364NOL8chr9

95076549

-FXNchr9

71661301

+
In-frameENST00000545558ENST00000396366NOL8chr9

95076549

-FXNchr9

71661301

+
intron-3CDSENST00000543985ENST00000377270NOL8chr9

95076549

-FXNchr9

71661301

+
intron-3CDSENST00000543985ENST00000396364NOL8chr9

95076549

-FXNchr9

71661301

+
intron-3CDSENST00000543985ENST00000396366NOL8chr9

95076549

-FXNchr9

71661301

+
intron-5UTRENST00000543985ENST00000498653NOL8chr9

95076549

-FXNchr9

71661301

+

check buttonORFfinder result based on the fusion transcript sequence of in-frame fusion genes.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandSeq length
(transcript)		BP loci
(transcript)		Predicted start
(transcript)		Predicted stop
(transcript)		Seq length
(amino acids)
ENST00000545558NOL8chr995076549-ENST00000396364FXNchr971661301+344628514933201902
ENST00000545558NOL8chr995076549-ENST00000377270FXNchr971661301+477028514933318941
ENST00000545558NOL8chr995076549-ENST00000396366FXNchr971661301+358728514933276927
ENST00000535387NOL8chr995076549-ENST00000396364FXNchr971661301+2953235802708902
ENST00000535387NOL8chr995076549-ENST00000377270FXNchr971661301+4277235802825941
ENST00000535387NOL8chr995076549-ENST00000396366FXNchr971661301+3094235802783927

check buttonDeepORF prediction of the coding potential based on the fusion transcript sequence of in-frame fusion genes. DeepORF is a coding potential classifier based on convolutional neural network by comparing the real Ribo-seq data. If the no-coding score < 0.5 and coding score > 0.5, then the in-frame fusion transcript is predicted as being likely translated.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandNo-coding scoreCoding score
ENST00000545558ENST00000396364NOL8chr995076549-FXNchr971661301+0.0007412450.9992587
ENST00000545558ENST00000377270NOL8chr995076549-FXNchr971661301+0.0003589340.99964106
ENST00000545558ENST00000396366NOL8chr995076549-FXNchr971661301+0.0004949480.99950504
ENST00000535387ENST00000396364NOL8chr995076549-FXNchr971661301+0.0011330470.99886703
ENST00000535387ENST00000377270NOL8chr995076549-FXNchr971661301+0.0004372770.9995627
ENST00000535387ENST00000396366NOL8chr995076549-FXNchr971661301+0.0007221490.9992779

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Fusion Genomic Features for NOL8-FXN


check buttonFusionAI prediction of the potential fusion gene breakpoint based on the pre-mature RNA sequence context (+/- 5kb of individual partner genes, total 20kb length sequence). FusionAI is a fusion gene breakpoint classifier based on convolutional neural network by comparing the fusion positive and negative sequence context of ~ 20K fusion gene data. From here, we can have the relative potentency of the 20K genomic sequence how individual sequnce will be likely used as the gene fusion breakpoints.
HgeneHchrHbpHstrandTgeneTchrTbpTstrand1-pp (fusion gene breakpoint)
NOL8chr995076548-FXNchr971661300+4.63E-050.99995375
NOL8chr995076548-FXNchr971661300+4.63E-050.99995375
NOL8chr995076548-FXNchr971661300+4.63E-050.99995375
NOL8chr995076548-FXNchr971661300+4.63E-050.99995375

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions. We integrated a total of 44 different types of human genomic feature loci information across five big categories including virus integration sites, repeats, structural variants, chromatin states, and gene expression regulation. More details are in help page.
genomic feature

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions that are ovelapped with the top 1% feature importance score regions. More details are in help page.
genomic feature of top 1%

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Fusion Protein Features for NOL8-FXN


check button Four levels of functional features of fusion genes
Go to FGviewer search page for the most frequent breakpoint (https://ccsmweb.uth.edu/FGviewer/chr9:95076549/chr9:71661301)
- FGviewer provides the online visualization of the retention search of the protein functional features across DNA, RNA, protein, and pathological levels.
- How to search
1. Put your fusion gene symbol.
2. Press the tab key until there will be shown the breakpoint information filled.
4. Go down and press 'Search' tab twice.
4. Go down to have the hyperlink of the search result.
5. Click the hyperlink.
6. See the FGviewer result for your fusion gene.
FGviewer

check buttonMain function of each fusion partner protein. (from UniProt)
HgeneTgene
NOL8

Q76FK4

FXN

Q16595

FUNCTION: Plays an essential role in the survival of diffuse-type gastric cancer cells. Acts as a nucleolar anchoring protein for DDX47. May be involved in regulation of gene expression at the post-transcriptional level or in ribosome biogenesis in cancer cells. {ECO:0000269|PubMed:14660641, ECO:0000269|PubMed:15132771, ECO:0000269|PubMed:16963496}.FUNCTION: Promotes the biosynthesis of heme and assembly and repair of iron-sulfur clusters by delivering Fe(2+) to proteins involved in these pathways. May play a role in the protection against iron-catalyzed oxidative stress through its ability to catalyze the oxidation of Fe(2+) to Fe(3+); the oligomeric form but not the monomeric form has in vitro ferroxidase activity. May be able to store large amounts of iron in the form of a ferrihydrite mineral by oligomerization; however, the physiological relevance is unsure as reports are conflicting and the function has only been shown using heterologous overexpression systems. Modulates the RNA-binding activity of ACO1. {ECO:0000269|PubMed:12785837, ECO:0000269|PubMed:15247478, ECO:0000269|PubMed:15641778, ECO:0000269|PubMed:16239244, ECO:0000269|PubMed:16608849, ECO:0000269|PubMed:20053667}.

check buttonRetention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at

download page


* Minus value of BPloci means that the break pointn is located before the CDS.
- In-frame and retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneNOL8chr9:95076549chr9:71661301ENST00000442668-717753_7797861168.0Coiled coilOntology_term=ECO:0000255
HgeneNOL8chr9:95076549chr9:71661301ENST00000535387-615753_7797861130.0Coiled coilOntology_term=ECO:0000255
HgeneNOL8chr9:95076549chr9:71661301ENST00000545558-717753_7797861168.0Coiled coilOntology_term=ECO:0000255
HgeneNOL8chr9:95076549chr9:71661301ENST00000358855-8188_897181100.0DomainRRM
HgeneNOL8chr9:95076549chr9:71661301ENST00000442668-7178_897861168.0DomainRRM
HgeneNOL8chr9:95076549chr9:71661301ENST00000535387-6158_897861130.0DomainRRM
HgeneNOL8chr9:95076549chr9:71661301ENST00000542053-6168_897181100.0DomainRRM
HgeneNOL8chr9:95076549chr9:71661301ENST00000545558-7178_897861168.0DomainRRM

- In-frame and not-retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneNOL8chr9:95076549chr9:71661301ENST00000358855-818753_7797181100.0Coiled coilOntology_term=ECO:0000255
HgeneNOL8chr9:95076549chr9:71661301ENST00000358855-818886_9247181100.0Coiled coilOntology_term=ECO:0000255
HgeneNOL8chr9:95076549chr9:71661301ENST00000442668-717886_9247861168.0Coiled coilOntology_term=ECO:0000255
HgeneNOL8chr9:95076549chr9:71661301ENST00000535387-615886_9247861130.0Coiled coilOntology_term=ECO:0000255
HgeneNOL8chr9:95076549chr9:71661301ENST00000542053-616753_7797181100.0Coiled coilOntology_term=ECO:0000255
HgeneNOL8chr9:95076549chr9:71661301ENST00000542053-616886_9247181100.0Coiled coilOntology_term=ECO:0000255
HgeneNOL8chr9:95076549chr9:71661301ENST00000545558-717886_9247861168.0Coiled coilOntology_term=ECO:0000255
HgeneNOL8chr9:95076549chr9:71661301ENST00000358855-8181113_11167181100.0Compositional biasPoly-Phe
HgeneNOL8chr9:95076549chr9:71661301ENST00000442668-7171113_11167861168.0Compositional biasPoly-Phe
HgeneNOL8chr9:95076549chr9:71661301ENST00000535387-6151113_11167861130.0Compositional biasPoly-Phe
HgeneNOL8chr9:95076549chr9:71661301ENST00000542053-6161113_11167181100.0Compositional biasPoly-Phe
HgeneNOL8chr9:95076549chr9:71661301ENST00000545558-7171113_11167861168.0Compositional biasPoly-Phe


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Fusion Gene Sequence for NOL8-FXN


check button For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. To have fusion amino acid sequence, we ran ORFfinder and chose the longest ORF among the all predicted ones.
>59570_59570_1_NOL8-FXN_NOL8_chr9_95076549_ENST00000535387_FXN_chr9_71661301_ENST00000377270_length(transcript)=4277nt_BP=2358nt
ATGAAAGTGAACAGAGAAACGAAGCGCCTTTATGTGGGTGGCCTTAGCCAGGACATTTCTGAGGCAGACCTACAAAATCAGTTCAGCAGA
TTTGGAGAAGTTTCGGATGTGGAGATCATCACACGGAAAGATGACCAAGGAAACCCACAGAAAGTTTTTGCATATATCAACATCAGTGTA
GCAGAAGCGGACCTGAAAAAATGTATGTCTGTTTTAAATAAAACAAAATGGAAAGGTGGAACATTACAAATTCAACTAGCAAAAGAAAGC
TTTCTGCACAGATTGGCCCAAGAGAGAGAAGCAGCAAAAGCTAAGAAAGAAGAATCAACAACAGGTAACGCCAACTTGTTAGAAAAGACA
GGAGGAGTGGATTTCCATATGAAAGCTGTGCCAGGGACAGAAGTGCCAGGGCATAAGAATTGGGTTGTGAGCAAATTTGGAAGAGTCTTA
CCTGTTCTTCACCTTAAAAATCAACATAAACGTAAAATCATCAAATATGATCCCTCAAAATACTGCCACAACCTGAAGAAGATAGGGGAG
GATTTCTCAAACACCATTCCTATATCCAGCCTGACTTGGGAATTAGAAGGAGGGAATGACCCTATGAGTAAGAAACGGCGAGGAGAGTTC
TCTGACTTTCATGGCCCTCCCAAGAAGATAATAAAAGTGCAGAAGGATGAGAGTTCCACTGGGTCTCTGGCCATGAGTACAAGGCCCAGG
AGGGTAATAGAGAGACCACCCTTAACACAGCAACAGGCTGCACAAAAAAGAACTTGTGATTCCATTACTCCTTCTAAATCATCTCCTGTA
CCTGTTTCTGATACTCAGAAACTTAAAAATCTACCTTTTAAGACTTCTGGCTTGGAAACTGCCAAGAAGAGAAACAGCATTTCTGATGAT
GATACTGATTCTGAAGATGAATTGAGAATGATGATTGCGAAAGAGGAAAACTTACAGAGAACTACACAACCCTCAATAAATGAATCTGAA
AGTGATCCTTTTGAAGTTGTAAGGGATGATTTCAAATCAGGCGTTCACAAACTGCATTCTTTAATAGGTTTAGGTATCAAAAATCGTGTC
TCTTGCCATGATAGTGATGATGATATTATGAGAAATGATCGTGAGTATGACTCAGGAGATACAGATGAAATTATTGCGATGAAAAAAAAT
GTTGCTAAGGTCAAAAACAGTACAGAATTTTCACAAATGGAAAAATCTACGAAGAAAACTTCTTTCAAAAATAGAGAAAACTGTGAGCTT
TCTGATCACTGTATTAAACTACAAAAAAGAAAAAGCAATGTAGAGTCAGCCCTCAGTCATGGATTAAAGTCTCTTAATCGTAAATCTCCC
TCTCACTCCAGTAGCAGTGAAGATGCTGATTCTGCATCAGAATTAGCTGACTCTGAAGGAGGTGAGGAGTATAATGCCATGATGAAAAAC
TGCCTTCGTGTGAATCTCACTTTAGCTGATTTGGAACAATTGGCTGGCAGTGATCTGAAGGTTCCAAATGAAGATACTAAGAGTGATGGA
CCAGAAACCACCACCCAATGCAAGTTTGACAGAGGCTCCAAGAGCCCCAAGACTCCCACTGGCCTCCGCAGAGGCCGACAGTGTATTCGT
CCTGCGGAGATTGTGGCTTCCCTGTTAGAAGGAGAGGAGAACACCTGTGGCAAACAGAAACCAAAGGAAAACAATTTAAAGCCAAAATTT
CAGGCTTTCAAGGGAGTAGGCTGTCTATATGAAAAGGAGTCAATGAAAAAATCCTTGAAAGACAGTGTTGCCTCTAACAATAAAGATCAG
AATTCCATGAAACATGAGGATCCCAGTATCATATCCATGGAAGATGGGTCCCCATATGTTAATGGCTCATTAGGTGAAGTGACTCCATGC
CAACATGCAAAGAAGGCGAATGGCCCAAACTATATTCAGCCTCAAAAAAGACAGACCACTTTTGAAAGCCAGGATCGCAAGGCAGTGTCC
CCTAGCAGTTCTGAAAAGAGAAGTAAGAATCCTATTTCTAGGCCATTAGAAGGTAAGAAGTCCTTAAGTCTTAGTGCAAAGACTCACAAC
ATAGGCTTTGACAAAGACAGCTGCCATAGTACCACAAAGACAGAAGCTTCACAGGAAGAGCGGTCTGATTCAAGCGGCCTCACATCTCTC
AAGAAATCACCAAAGGTCTCATCCAAGGACACTCGGGAAATCAAAACTGATTTCTCACTTTCTATTAGTAATTCGTCAGATGTGAGTGCT
AAAGATAAGCATGCTGAAGACAATGAGAAGCGTTTGGCAGCCTTGGAAGCGAGGCAAAAAGCAAAAGAAGTGCAGAAGAAGCTGGTGCAT
AATGCTCTGGCAAATTTGAGTTCGAACCAACGTGGCCTCAACCAGATTTGGAATGTCAAAAAGCAGAGTGTCTATTTGATGAATTTGAGG
AAATCTGGAACTTTGGGCCACCCAGGCTCTCTAGATGAGACCACCTATGAAAGACTAGCAGAGGAAACGCTGGACTCTTTAGCAGAGTTT
TTTGAAGACCTTGCAGACAAGCCATACACGTTTGAGGACTATGATGTCTCCTTTGGGAGTGGTGTCTTAACTGTCAAACTGGGTGGAGAT
CTAGGAACCTATGTGATCAACAAGCAGACGCCAAACAAGCAAATCTGGCTATCTTCTCCATCCAGTGGACCTAAGCGTTATGACTGGACT
GGGAAAAACTGGGTGTACTCCCACGACGGCGTGTCCCTCCATGAGCTGCTGGCCGCAGAGCTCACTAAAGCCTTAAAAACCAAACTGGAC
TTGTCTTCCTTGGCCTATTCCGGAAAAGATGCTTGATGCCCAGCCCCGTTTTAAGGACATTAAAAGCTATCAGGCCAAGACCCCAGCTTC
ATTATGCAGCTGAGGTCTGTTTTTTGTTGTTGTTGTTGTTTATTTTTTTTATTCCTGCTTTTGAGGACAGTTGGGCTATGTGTCACAGCT
CTGTAGAAAGAATGTGTTGCCTCCTACCTTGCCCCCAAGTTCTGATTTTTAATTTCTATGGAAGATTTTTTGGATTGTCGGATTTCCTCC
CTCACATGATACCCCTTATCTTTTATAATGTCTTATGCCTATACCTGAATATAACAACCTTTAAAAAAGCAAAATAATAAGAAGGAAAAA
TTCCAGGAGGGAAAATGAATTGTCTTCACTCTTCATTCTTTGAAGGATTTACTGCAAGAAGTACATGAAGAGCAGCTGGTCAACCTGCTC
ACTGTTCTATCTCCAAATGAGACACATTAAAGGGTAGCCTACAAATGTTTTCAGGCTTCTTTCAAAGTGTAAGCACTTCTGAGCTCTTTA
GCATTGAAGTGTCGAAAGCAACTCACACGGGAAGATCATTTCTTATTTGTGCTCTGTGACTGCCAAGGTGTGGCCTGCACTGGGTTGTCC
AGGGAGACCTAGTGCTGTTTCTCCCACATATTCACATACGTGTCTGTGTGTATATATATTTTTTCAATTTAAAGGTTAGTATGGAATCAG
CTGCTACAAGAATGCAAAAAATCTTCCAAAGACAAGAAAAGAGGAAAAAAAGCCGTTTTCATGAGCTGAGTGATGTAGCGTAACAAACAA
AATCATGGAGCTGAGGAGGTGCCTTGTAAACATGAAGGGGCAGATAAAGGAAGGAGATACTCATGTTGATAAAGAGAGCCCTGGTCCTAG
ACATAGTTCAGCCACAAAGTAGTTGTCCCTTTGTGGACAAGTTTCCCAAATTCCCTGGACCTCTGCTTCCCCATCTGTTAAATGAGAGAA
TAGAGTATGGTTGATTCCCAGCATTCAGTGGTCCTGTCAAGCAACCTAACAGGCTAGTTCTAATTCCCTATTGGGTAGATGAGGGGATGA
CAAAGAACAGTTTTTAAGCTATATAGGAAACATTGTTATTGGTGTTGCCCTATCGTGATTTCAGTTGAATTCATGTGAAAATAATAGCCA
TCCTTGGCCTGGCGCGGTGGCTCACACCTGTAATCCCAGCACTTTTGGAGGCCAAGGTGGGTGGATCACCTGAGGTCAGGAGTTCAAGAC
CAGCCTGGCCAACATGATGAAACCCCGTCTCTACTAAAAATACAAAAAATTAGCCGGGCATGATGGCAGGTGCCTGTAATCCCAGCTACT
TGGGAGGCTGAAGCGGAAGAATCGCTTGAACCCAGAGGTGGAGGTTGCAGTGAGCCGAGATCGTGCCATTGCACTGTAACCTGGGTGACT

>59570_59570_1_NOL8-FXN_NOL8_chr9_95076549_ENST00000535387_FXN_chr9_71661301_ENST00000377270_length(amino acids)=941AA_BP=786
MKVNRETKRLYVGGLSQDISEADLQNQFSRFGEVSDVEIITRKDDQGNPQKVFAYINISVAEADLKKCMSVLNKTKWKGGTLQIQLAKES
FLHRLAQEREAAKAKKEESTTGNANLLEKTGGVDFHMKAVPGTEVPGHKNWVVSKFGRVLPVLHLKNQHKRKIIKYDPSKYCHNLKKIGE
DFSNTIPISSLTWELEGGNDPMSKKRRGEFSDFHGPPKKIIKVQKDESSTGSLAMSTRPRRVIERPPLTQQQAAQKRTCDSITPSKSSPV
PVSDTQKLKNLPFKTSGLETAKKRNSISDDDTDSEDELRMMIAKEENLQRTTQPSINESESDPFEVVRDDFKSGVHKLHSLIGLGIKNRV
SCHDSDDDIMRNDREYDSGDTDEIIAMKKNVAKVKNSTEFSQMEKSTKKTSFKNRENCELSDHCIKLQKRKSNVESALSHGLKSLNRKSP
SHSSSSEDADSASELADSEGGEEYNAMMKNCLRVNLTLADLEQLAGSDLKVPNEDTKSDGPETTTQCKFDRGSKSPKTPTGLRRGRQCIR
PAEIVASLLEGEENTCGKQKPKENNLKPKFQAFKGVGCLYEKESMKKSLKDSVASNNKDQNSMKHEDPSIISMEDGSPYVNGSLGEVTPC
QHAKKANGPNYIQPQKRQTTFESQDRKAVSPSSSEKRSKNPISRPLEGKKSLSLSAKTHNIGFDKDSCHSTTKTEASQEERSDSSGLTSL
KKSPKVSSKDTREIKTDFSLSISNSSDVSAKDKHAEDNEKRLAALEARQKAKEVQKKLVHNALANLSSNQRGLNQIWNVKKQSVYLMNLR
KSGTLGHPGSLDETTYERLAEETLDSLAEFFEDLADKPYTFEDYDVSFGSGVLTVKLGGDLGTYVINKQTPNKQIWLSSPSSGPKRYDWT

--------------------------------------------------------------
>59570_59570_2_NOL8-FXN_NOL8_chr9_95076549_ENST00000535387_FXN_chr9_71661301_ENST00000396364_length(transcript)=2953nt_BP=2358nt
ATGAAAGTGAACAGAGAAACGAAGCGCCTTTATGTGGGTGGCCTTAGCCAGGACATTTCTGAGGCAGACCTACAAAATCAGTTCAGCAGA
TTTGGAGAAGTTTCGGATGTGGAGATCATCACACGGAAAGATGACCAAGGAAACCCACAGAAAGTTTTTGCATATATCAACATCAGTGTA
GCAGAAGCGGACCTGAAAAAATGTATGTCTGTTTTAAATAAAACAAAATGGAAAGGTGGAACATTACAAATTCAACTAGCAAAAGAAAGC
TTTCTGCACAGATTGGCCCAAGAGAGAGAAGCAGCAAAAGCTAAGAAAGAAGAATCAACAACAGGTAACGCCAACTTGTTAGAAAAGACA
GGAGGAGTGGATTTCCATATGAAAGCTGTGCCAGGGACAGAAGTGCCAGGGCATAAGAATTGGGTTGTGAGCAAATTTGGAAGAGTCTTA
CCTGTTCTTCACCTTAAAAATCAACATAAACGTAAAATCATCAAATATGATCCCTCAAAATACTGCCACAACCTGAAGAAGATAGGGGAG
GATTTCTCAAACACCATTCCTATATCCAGCCTGACTTGGGAATTAGAAGGAGGGAATGACCCTATGAGTAAGAAACGGCGAGGAGAGTTC
TCTGACTTTCATGGCCCTCCCAAGAAGATAATAAAAGTGCAGAAGGATGAGAGTTCCACTGGGTCTCTGGCCATGAGTACAAGGCCCAGG
AGGGTAATAGAGAGACCACCCTTAACACAGCAACAGGCTGCACAAAAAAGAACTTGTGATTCCATTACTCCTTCTAAATCATCTCCTGTA
CCTGTTTCTGATACTCAGAAACTTAAAAATCTACCTTTTAAGACTTCTGGCTTGGAAACTGCCAAGAAGAGAAACAGCATTTCTGATGAT
GATACTGATTCTGAAGATGAATTGAGAATGATGATTGCGAAAGAGGAAAACTTACAGAGAACTACACAACCCTCAATAAATGAATCTGAA
AGTGATCCTTTTGAAGTTGTAAGGGATGATTTCAAATCAGGCGTTCACAAACTGCATTCTTTAATAGGTTTAGGTATCAAAAATCGTGTC
TCTTGCCATGATAGTGATGATGATATTATGAGAAATGATCGTGAGTATGACTCAGGAGATACAGATGAAATTATTGCGATGAAAAAAAAT
GTTGCTAAGGTCAAAAACAGTACAGAATTTTCACAAATGGAAAAATCTACGAAGAAAACTTCTTTCAAAAATAGAGAAAACTGTGAGCTT
TCTGATCACTGTATTAAACTACAAAAAAGAAAAAGCAATGTAGAGTCAGCCCTCAGTCATGGATTAAAGTCTCTTAATCGTAAATCTCCC
TCTCACTCCAGTAGCAGTGAAGATGCTGATTCTGCATCAGAATTAGCTGACTCTGAAGGAGGTGAGGAGTATAATGCCATGATGAAAAAC
TGCCTTCGTGTGAATCTCACTTTAGCTGATTTGGAACAATTGGCTGGCAGTGATCTGAAGGTTCCAAATGAAGATACTAAGAGTGATGGA
CCAGAAACCACCACCCAATGCAAGTTTGACAGAGGCTCCAAGAGCCCCAAGACTCCCACTGGCCTCCGCAGAGGCCGACAGTGTATTCGT
CCTGCGGAGATTGTGGCTTCCCTGTTAGAAGGAGAGGAGAACACCTGTGGCAAACAGAAACCAAAGGAAAACAATTTAAAGCCAAAATTT
CAGGCTTTCAAGGGAGTAGGCTGTCTATATGAAAAGGAGTCAATGAAAAAATCCTTGAAAGACAGTGTTGCCTCTAACAATAAAGATCAG
AATTCCATGAAACATGAGGATCCCAGTATCATATCCATGGAAGATGGGTCCCCATATGTTAATGGCTCATTAGGTGAAGTGACTCCATGC
CAACATGCAAAGAAGGCGAATGGCCCAAACTATATTCAGCCTCAAAAAAGACAGACCACTTTTGAAAGCCAGGATCGCAAGGCAGTGTCC
CCTAGCAGTTCTGAAAAGAGAAGTAAGAATCCTATTTCTAGGCCATTAGAAGGTAAGAAGTCCTTAAGTCTTAGTGCAAAGACTCACAAC
ATAGGCTTTGACAAAGACAGCTGCCATAGTACCACAAAGACAGAAGCTTCACAGGAAGAGCGGTCTGATTCAAGCGGCCTCACATCTCTC
AAGAAATCACCAAAGGTCTCATCCAAGGACACTCGGGAAATCAAAACTGATTTCTCACTTTCTATTAGTAATTCGTCAGATGTGAGTGCT
AAAGATAAGCATGCTGAAGACAATGAGAAGCGTTTGGCAGCCTTGGAAGCGAGGCAAAAAGCAAAAGAAGTGCAGAAGAAGCTGGTGCAT
AATGCTCTGGCAAATTTGAGTTCGAACCAACGTGGCCTCAACCAGATTTGGAATGTCAAAAAGCAGAGTGTCTATTTGATGAATTTGAGG
AAATCTGGAACTTTGGGCCACCCAGGCTCTCTAGATGAGACCACCTATGAAAGACTAGCAGAGGAAACGCTGGACTCTTTAGCAGAGTTT
TTTGAAGACCTTGCAGACAAGCCATACACGTTTGAGGACTATGATGTCTCCTTTGGGAGTGGTGTCTTAACTGTCAAACTGGGTGGAGAT
CTAGGAACCTATGTGATCAACAAGCAGACGCCAAACAAGCAAATCTGGCTATCTTCTCCATCCAGGTTAACGTGGCTCCTGTGGCTGTTC
CATCCCTGAGGAAAAGTGAGGACCATGCTCTCCAAACAGGCCATGTGCTGGACTACCTCTGTTTCTGTCTCCTGGGATTCCAATCAGCAA
GTGAGCAACGAAGCAACCCAGACAGTGTGGTTCATAGGATGGCTGGGTAAGTGGCTGTTTGTTTTTTCCTTACTGTGGATATGTATCAGT

>59570_59570_2_NOL8-FXN_NOL8_chr9_95076549_ENST00000535387_FXN_chr9_71661301_ENST00000396364_length(amino acids)=902AA_BP=786
MKVNRETKRLYVGGLSQDISEADLQNQFSRFGEVSDVEIITRKDDQGNPQKVFAYINISVAEADLKKCMSVLNKTKWKGGTLQIQLAKES
FLHRLAQEREAAKAKKEESTTGNANLLEKTGGVDFHMKAVPGTEVPGHKNWVVSKFGRVLPVLHLKNQHKRKIIKYDPSKYCHNLKKIGE
DFSNTIPISSLTWELEGGNDPMSKKRRGEFSDFHGPPKKIIKVQKDESSTGSLAMSTRPRRVIERPPLTQQQAAQKRTCDSITPSKSSPV
PVSDTQKLKNLPFKTSGLETAKKRNSISDDDTDSEDELRMMIAKEENLQRTTQPSINESESDPFEVVRDDFKSGVHKLHSLIGLGIKNRV
SCHDSDDDIMRNDREYDSGDTDEIIAMKKNVAKVKNSTEFSQMEKSTKKTSFKNRENCELSDHCIKLQKRKSNVESALSHGLKSLNRKSP
SHSSSSEDADSASELADSEGGEEYNAMMKNCLRVNLTLADLEQLAGSDLKVPNEDTKSDGPETTTQCKFDRGSKSPKTPTGLRRGRQCIR
PAEIVASLLEGEENTCGKQKPKENNLKPKFQAFKGVGCLYEKESMKKSLKDSVASNNKDQNSMKHEDPSIISMEDGSPYVNGSLGEVTPC
QHAKKANGPNYIQPQKRQTTFESQDRKAVSPSSSEKRSKNPISRPLEGKKSLSLSAKTHNIGFDKDSCHSTTKTEASQEERSDSSGLTSL
KKSPKVSSKDTREIKTDFSLSISNSSDVSAKDKHAEDNEKRLAALEARQKAKEVQKKLVHNALANLSSNQRGLNQIWNVKKQSVYLMNLR
KSGTLGHPGSLDETTYERLAEETLDSLAEFFEDLADKPYTFEDYDVSFGSGVLTVKLGGDLGTYVINKQTPNKQIWLSSPSRLTWLLWLF

--------------------------------------------------------------
>59570_59570_3_NOL8-FXN_NOL8_chr9_95076549_ENST00000535387_FXN_chr9_71661301_ENST00000396366_length(transcript)=3094nt_BP=2358nt
ATGAAAGTGAACAGAGAAACGAAGCGCCTTTATGTGGGTGGCCTTAGCCAGGACATTTCTGAGGCAGACCTACAAAATCAGTTCAGCAGA
TTTGGAGAAGTTTCGGATGTGGAGATCATCACACGGAAAGATGACCAAGGAAACCCACAGAAAGTTTTTGCATATATCAACATCAGTGTA
GCAGAAGCGGACCTGAAAAAATGTATGTCTGTTTTAAATAAAACAAAATGGAAAGGTGGAACATTACAAATTCAACTAGCAAAAGAAAGC
TTTCTGCACAGATTGGCCCAAGAGAGAGAAGCAGCAAAAGCTAAGAAAGAAGAATCAACAACAGGTAACGCCAACTTGTTAGAAAAGACA
GGAGGAGTGGATTTCCATATGAAAGCTGTGCCAGGGACAGAAGTGCCAGGGCATAAGAATTGGGTTGTGAGCAAATTTGGAAGAGTCTTA
CCTGTTCTTCACCTTAAAAATCAACATAAACGTAAAATCATCAAATATGATCCCTCAAAATACTGCCACAACCTGAAGAAGATAGGGGAG
GATTTCTCAAACACCATTCCTATATCCAGCCTGACTTGGGAATTAGAAGGAGGGAATGACCCTATGAGTAAGAAACGGCGAGGAGAGTTC
TCTGACTTTCATGGCCCTCCCAAGAAGATAATAAAAGTGCAGAAGGATGAGAGTTCCACTGGGTCTCTGGCCATGAGTACAAGGCCCAGG
AGGGTAATAGAGAGACCACCCTTAACACAGCAACAGGCTGCACAAAAAAGAACTTGTGATTCCATTACTCCTTCTAAATCATCTCCTGTA
CCTGTTTCTGATACTCAGAAACTTAAAAATCTACCTTTTAAGACTTCTGGCTTGGAAACTGCCAAGAAGAGAAACAGCATTTCTGATGAT
GATACTGATTCTGAAGATGAATTGAGAATGATGATTGCGAAAGAGGAAAACTTACAGAGAACTACACAACCCTCAATAAATGAATCTGAA
AGTGATCCTTTTGAAGTTGTAAGGGATGATTTCAAATCAGGCGTTCACAAACTGCATTCTTTAATAGGTTTAGGTATCAAAAATCGTGTC
TCTTGCCATGATAGTGATGATGATATTATGAGAAATGATCGTGAGTATGACTCAGGAGATACAGATGAAATTATTGCGATGAAAAAAAAT
GTTGCTAAGGTCAAAAACAGTACAGAATTTTCACAAATGGAAAAATCTACGAAGAAAACTTCTTTCAAAAATAGAGAAAACTGTGAGCTT
TCTGATCACTGTATTAAACTACAAAAAAGAAAAAGCAATGTAGAGTCAGCCCTCAGTCATGGATTAAAGTCTCTTAATCGTAAATCTCCC
TCTCACTCCAGTAGCAGTGAAGATGCTGATTCTGCATCAGAATTAGCTGACTCTGAAGGAGGTGAGGAGTATAATGCCATGATGAAAAAC
TGCCTTCGTGTGAATCTCACTTTAGCTGATTTGGAACAATTGGCTGGCAGTGATCTGAAGGTTCCAAATGAAGATACTAAGAGTGATGGA
CCAGAAACCACCACCCAATGCAAGTTTGACAGAGGCTCCAAGAGCCCCAAGACTCCCACTGGCCTCCGCAGAGGCCGACAGTGTATTCGT
CCTGCGGAGATTGTGGCTTCCCTGTTAGAAGGAGAGGAGAACACCTGTGGCAAACAGAAACCAAAGGAAAACAATTTAAAGCCAAAATTT
CAGGCTTTCAAGGGAGTAGGCTGTCTATATGAAAAGGAGTCAATGAAAAAATCCTTGAAAGACAGTGTTGCCTCTAACAATAAAGATCAG
AATTCCATGAAACATGAGGATCCCAGTATCATATCCATGGAAGATGGGTCCCCATATGTTAATGGCTCATTAGGTGAAGTGACTCCATGC
CAACATGCAAAGAAGGCGAATGGCCCAAACTATATTCAGCCTCAAAAAAGACAGACCACTTTTGAAAGCCAGGATCGCAAGGCAGTGTCC
CCTAGCAGTTCTGAAAAGAGAAGTAAGAATCCTATTTCTAGGCCATTAGAAGGTAAGAAGTCCTTAAGTCTTAGTGCAAAGACTCACAAC
ATAGGCTTTGACAAAGACAGCTGCCATAGTACCACAAAGACAGAAGCTTCACAGGAAGAGCGGTCTGATTCAAGCGGCCTCACATCTCTC
AAGAAATCACCAAAGGTCTCATCCAAGGACACTCGGGAAATCAAAACTGATTTCTCACTTTCTATTAGTAATTCGTCAGATGTGAGTGCT
AAAGATAAGCATGCTGAAGACAATGAGAAGCGTTTGGCAGCCTTGGAAGCGAGGCAAAAAGCAAAAGAAGTGCAGAAGAAGCTGGTGCAT
AATGCTCTGGCAAATTTGAGTTCGAACCAACGTGGCCTCAACCAGATTTGGAATGTCAAAAAGCAGAGTGTCTATTTGATGAATTTGAGG
AAATCTGGAACTTTGGGCCACCCAGGCTCTCTAGATGAGACCACCTATGAAAGACTAGCAGAGGAAACGCTGGACTCTTTAGCAGAGTTT
TTTGAAGACCTTGCAGACAAGCCATACACGTTTGAGGACTATGATGTCTCCTTTGGGAGTGGTGTCTTAACTGTCAAACTGGGTGGAGAT
CTAGGAACCTATGTGATCAACAAGCAGACGCCAAACAAGCAAATCTGGCTATCTTCTCCATCCAGGTATGTAGTGGACCTAAGCGTTATG
ACTGGACTGGGAAAAACTGGGTGTACTCCCACGACGGCGTGTCCCTCCATGAGCTGCTGGCCGCAGAGCTCACTAAAGCCTTAAAAACCA
AACTGGACTTGTCTTCCTTGGCCTATTCCGGAAAAGATGCTTGATGCCCAGCCCCGTTTTAAGGACATTAAAAGCTATCAGGCCAAGACC
CCAGCTTCATTATGCAGCTGAGGTCTGTTTTTTGTTGTTGTTGTTGTTTATTTTTTTTATTCCTGCTTTTGAGGACAGTTGGGCTATGTG
TCACAGCTCTGTAGAAAGAATGTGTTGCCTCCTACCTTGCCCCCAAGTTCTGATTTTTAATTTCTATGGAAGATTTTTTGGATTGTCGGA

>59570_59570_3_NOL8-FXN_NOL8_chr9_95076549_ENST00000535387_FXN_chr9_71661301_ENST00000396366_length(amino acids)=927AA_BP=786
MKVNRETKRLYVGGLSQDISEADLQNQFSRFGEVSDVEIITRKDDQGNPQKVFAYINISVAEADLKKCMSVLNKTKWKGGTLQIQLAKES
FLHRLAQEREAAKAKKEESTTGNANLLEKTGGVDFHMKAVPGTEVPGHKNWVVSKFGRVLPVLHLKNQHKRKIIKYDPSKYCHNLKKIGE
DFSNTIPISSLTWELEGGNDPMSKKRRGEFSDFHGPPKKIIKVQKDESSTGSLAMSTRPRRVIERPPLTQQQAAQKRTCDSITPSKSSPV
PVSDTQKLKNLPFKTSGLETAKKRNSISDDDTDSEDELRMMIAKEENLQRTTQPSINESESDPFEVVRDDFKSGVHKLHSLIGLGIKNRV
SCHDSDDDIMRNDREYDSGDTDEIIAMKKNVAKVKNSTEFSQMEKSTKKTSFKNRENCELSDHCIKLQKRKSNVESALSHGLKSLNRKSP
SHSSSSEDADSASELADSEGGEEYNAMMKNCLRVNLTLADLEQLAGSDLKVPNEDTKSDGPETTTQCKFDRGSKSPKTPTGLRRGRQCIR
PAEIVASLLEGEENTCGKQKPKENNLKPKFQAFKGVGCLYEKESMKKSLKDSVASNNKDQNSMKHEDPSIISMEDGSPYVNGSLGEVTPC
QHAKKANGPNYIQPQKRQTTFESQDRKAVSPSSSEKRSKNPISRPLEGKKSLSLSAKTHNIGFDKDSCHSTTKTEASQEERSDSSGLTSL
KKSPKVSSKDTREIKTDFSLSISNSSDVSAKDKHAEDNEKRLAALEARQKAKEVQKKLVHNALANLSSNQRGLNQIWNVKKQSVYLMNLR
KSGTLGHPGSLDETTYERLAEETLDSLAEFFEDLADKPYTFEDYDVSFGSGVLTVKLGGDLGTYVINKQTPNKQIWLSSPSRYVVDLSVM

--------------------------------------------------------------
>59570_59570_4_NOL8-FXN_NOL8_chr9_95076549_ENST00000545558_FXN_chr9_71661301_ENST00000377270_length(transcript)=4770nt_BP=2851nt
AGAAGTTAGGGGCTGCAGCGGCGCTGGCTTTAGGTGAACGACGTGGTGAGGAGTGGGTTTCGGGCATGAGAAGTCACAGGGCCGTTTCCT
AGTCTCTCTTCACTTCTTTGGGTCTTCTCAGAGAAAGAAGGCTGCCGTGGGTAGGCTGGGGGCGGAGACTATCGGGAAGAGGTAGGCCGA
AGTTCTGCCCAGAATACACGCCATGTGGTGGACGCTGGTTGGGAGTCTCTTCTGGAAAGAGTCTGTCAGCTCTTGGGGAAGGGAAGGGCG
AGAGCTGAGCGCCTGCCGGGTGCTAAACGAAATGAGAGATACTATGATGGGCCCTAGTACCTCTGGAAAAGTTTTCCTGAGTCCCCTGTG
ATACAGCAACCTTCATAGTATAGTGTTAAGAATTCCAAGTTCTGAAGGTAGACCTGCATTATAATCCTGGATTCACTAATTTTCGAAAAT
TACTTTTCCCACTGAAACACACCCAAGTATATGCCCAGCCTTCATGAAAGTGAACAGAGAAACGAAGCGCCTTTATGTGGGTGGCCTTAG
CCAGGACATTTCTGAGGCAGACCTACAAAATCAGTTCAGCAGATTTGGAGAAGTTTCGGATGTGGAGATCATCACACGGAAAGATGACCA
AGGAAACCCACAGAAAGTTTTTGCATATATCAACATCAGTGTAGCAGAAGCGGACCTGAAAAAATGTATGTCTGTTTTAAATAAAACAAA
ATGGAAAGGTGGAACATTACAAATTCAACTAGCAAAAGAAAGCTTTCTGCACAGATTGGCCCAAGAGAGAGAAGCAGCAAAAGCTAAGAA
AGAAGAATCAACAACAGGTAACGCCAACTTGTTAGAAAAGACAGGAGGAGTGGATTTCCATATGAAAGCTGTGCCAGGGACAGAAGTGCC
AGGGCATAAGAATTGGGTTGTGAGCAAATTTGGAAGAGTCTTACCTGTTCTTCACCTTAAAAATCAACATAAACGTAAAATCATCAAATA
TGATCCCTCAAAATACTGCCACAACCTGAAGAAGATAGGGGAGGATTTCTCAAACACCATTCCTATATCCAGCCTGACTTGGGAATTAGA
AGGAGGGAATGACCCTATGAGTAAGAAACGGCGAGGAGAGTTCTCTGACTTTCATGGCCCTCCCAAGAAGATAATAAAAGTGCAGAAGGA
TGAGAGTTCCACTGGGTCTCTGGCCATGAGTACAAGGCCCAGGAGGGTAATAGAGAGACCACCCTTAACACAGCAACAGGCTGCACAAAA
AAGAACTTGTGATTCCATTACTCCTTCTAAATCATCTCCTGTACCTGTTTCTGATACTCAGAAACTTAAAAATCTACCTTTTAAGACTTC
TGGCTTGGAAACTGCCAAGAAGAGAAACAGCATTTCTGATGATGATACTGATTCTGAAGATGAATTGAGAATGATGATTGCGAAAGAGGA
AAACTTACAGAGAACTACACAACCCTCAATAAATGAATCTGAAAGTGATCCTTTTGAAGTTGTAAGGGATGATTTCAAATCAGGCGTTCA
CAAACTGCATTCTTTAATAGGTTTAGGTATCAAAAATCGTGTCTCTTGCCATGATAGTGATGATGATATTATGAGAAATGATCGTGAGTA
TGACTCAGGAGATACAGATGAAATTATTGCGATGAAAAAAAATGTTGCTAAGGTCAAAAACAGTACAGAATTTTCACAAATGGAAAAATC
TACGAAGAAAACTTCTTTCAAAAATAGAGAAAACTGTGAGCTTTCTGATCACTGTATTAAACTACAAAAAAGAAAAAGCAATGTAGAGTC
AGCCCTCAGTCATGGATTAAAGTCTCTTAATCGTAAATCTCCCTCTCACTCCAGTAGCAGTGAAGATGCTGATTCTGCATCAGAATTAGC
TGACTCTGAAGGAGGTGAGGAGTATAATGCCATGATGAAAAACTGCCTTCGTGTGAATCTCACTTTAGCTGATTTGGAACAATTGGCTGG
CAGTGATCTGAAGGTTCCAAATGAAGATACTAAGAGTGATGGACCAGAAACCACCACCCAATGCAAGTTTGACAGAGGCTCCAAGAGCCC
CAAGACTCCCACTGGCCTCCGCAGAGGCCGACAGTGTATTCGTCCTGCGGAGATTGTGGCTTCCCTGTTAGAAGGAGAGGAGAACACCTG
TGGCAAACAGAAACCAAAGGAAAACAATTTAAAGCCAAAATTTCAGGCTTTCAAGGGAGTAGGCTGTCTATATGAAAAGGAGTCAATGAA
AAAATCCTTGAAAGACAGTGTTGCCTCTAACAATAAAGATCAGAATTCCATGAAACATGAGGATCCCAGTATCATATCCATGGAAGATGG
GTCCCCATATGTTAATGGCTCATTAGGTGAAGTGACTCCATGCCAACATGCAAAGAAGGCGAATGGCCCAAACTATATTCAGCCTCAAAA
AAGACAGACCACTTTTGAAAGCCAGGATCGCAAGGCAGTGTCCCCTAGCAGTTCTGAAAAGAGAAGTAAGAATCCTATTTCTAGGCCATT
AGAAGGTAAGAAGTCCTTAAGTCTTAGTGCAAAGACTCACAACATAGGCTTTGACAAAGACAGCTGCCATAGTACCACAAAGACAGAAGC
TTCACAGGAAGAGCGGTCTGATTCAAGCGGCCTCACATCTCTCAAGAAATCACCAAAGGTCTCATCCAAGGACACTCGGGAAATCAAAAC
TGATTTCTCACTTTCTATTAGTAATTCGTCAGATGTGAGTGCTAAAGATAAGCATGCTGAAGACAATGAGAAGCGTTTGGCAGCCTTGGA
AGCGAGGCAAAAAGCAAAAGAAGTGCAGAAGAAGCTGGTGCATAATGCTCTGGCAAATTTGAGTTCGAACCAACGTGGCCTCAACCAGAT
TTGGAATGTCAAAAAGCAGAGTGTCTATTTGATGAATTTGAGGAAATCTGGAACTTTGGGCCACCCAGGCTCTCTAGATGAGACCACCTA
TGAAAGACTAGCAGAGGAAACGCTGGACTCTTTAGCAGAGTTTTTTGAAGACCTTGCAGACAAGCCATACACGTTTGAGGACTATGATGT
CTCCTTTGGGAGTGGTGTCTTAACTGTCAAACTGGGTGGAGATCTAGGAACCTATGTGATCAACAAGCAGACGCCAAACAAGCAAATCTG
GCTATCTTCTCCATCCAGTGGACCTAAGCGTTATGACTGGACTGGGAAAAACTGGGTGTACTCCCACGACGGCGTGTCCCTCCATGAGCT
GCTGGCCGCAGAGCTCACTAAAGCCTTAAAAACCAAACTGGACTTGTCTTCCTTGGCCTATTCCGGAAAAGATGCTTGATGCCCAGCCCC
GTTTTAAGGACATTAAAAGCTATCAGGCCAAGACCCCAGCTTCATTATGCAGCTGAGGTCTGTTTTTTGTTGTTGTTGTTGTTTATTTTT
TTTATTCCTGCTTTTGAGGACAGTTGGGCTATGTGTCACAGCTCTGTAGAAAGAATGTGTTGCCTCCTACCTTGCCCCCAAGTTCTGATT
TTTAATTTCTATGGAAGATTTTTTGGATTGTCGGATTTCCTCCCTCACATGATACCCCTTATCTTTTATAATGTCTTATGCCTATACCTG
AATATAACAACCTTTAAAAAAGCAAAATAATAAGAAGGAAAAATTCCAGGAGGGAAAATGAATTGTCTTCACTCTTCATTCTTTGAAGGA
TTTACTGCAAGAAGTACATGAAGAGCAGCTGGTCAACCTGCTCACTGTTCTATCTCCAAATGAGACACATTAAAGGGTAGCCTACAAATG
TTTTCAGGCTTCTTTCAAAGTGTAAGCACTTCTGAGCTCTTTAGCATTGAAGTGTCGAAAGCAACTCACACGGGAAGATCATTTCTTATT
TGTGCTCTGTGACTGCCAAGGTGTGGCCTGCACTGGGTTGTCCAGGGAGACCTAGTGCTGTTTCTCCCACATATTCACATACGTGTCTGT
GTGTATATATATTTTTTCAATTTAAAGGTTAGTATGGAATCAGCTGCTACAAGAATGCAAAAAATCTTCCAAAGACAAGAAAAGAGGAAA
AAAAGCCGTTTTCATGAGCTGAGTGATGTAGCGTAACAAACAAAATCATGGAGCTGAGGAGGTGCCTTGTAAACATGAAGGGGCAGATAA
AGGAAGGAGATACTCATGTTGATAAAGAGAGCCCTGGTCCTAGACATAGTTCAGCCACAAAGTAGTTGTCCCTTTGTGGACAAGTTTCCC
AAATTCCCTGGACCTCTGCTTCCCCATCTGTTAAATGAGAGAATAGAGTATGGTTGATTCCCAGCATTCAGTGGTCCTGTCAAGCAACCT
AACAGGCTAGTTCTAATTCCCTATTGGGTAGATGAGGGGATGACAAAGAACAGTTTTTAAGCTATATAGGAAACATTGTTATTGGTGTTG
CCCTATCGTGATTTCAGTTGAATTCATGTGAAAATAATAGCCATCCTTGGCCTGGCGCGGTGGCTCACACCTGTAATCCCAGCACTTTTG
GAGGCCAAGGTGGGTGGATCACCTGAGGTCAGGAGTTCAAGACCAGCCTGGCCAACATGATGAAACCCCGTCTCTACTAAAAATACAAAA
AATTAGCCGGGCATGATGGCAGGTGCCTGTAATCCCAGCTACTTGGGAGGCTGAAGCGGAAGAATCGCTTGAACCCAGAGGTGGAGGTTG
CAGTGAGCCGAGATCGTGCCATTGCACTGTAACCTGGGTGACTGAGCAAAACTCTGTCTCAAAATAATAATAACAATATAATAATAATAA

>59570_59570_4_NOL8-FXN_NOL8_chr9_95076549_ENST00000545558_FXN_chr9_71661301_ENST00000377270_length(amino acids)=941AA_BP=786
MKVNRETKRLYVGGLSQDISEADLQNQFSRFGEVSDVEIITRKDDQGNPQKVFAYINISVAEADLKKCMSVLNKTKWKGGTLQIQLAKES
FLHRLAQEREAAKAKKEESTTGNANLLEKTGGVDFHMKAVPGTEVPGHKNWVVSKFGRVLPVLHLKNQHKRKIIKYDPSKYCHNLKKIGE
DFSNTIPISSLTWELEGGNDPMSKKRRGEFSDFHGPPKKIIKVQKDESSTGSLAMSTRPRRVIERPPLTQQQAAQKRTCDSITPSKSSPV
PVSDTQKLKNLPFKTSGLETAKKRNSISDDDTDSEDELRMMIAKEENLQRTTQPSINESESDPFEVVRDDFKSGVHKLHSLIGLGIKNRV
SCHDSDDDIMRNDREYDSGDTDEIIAMKKNVAKVKNSTEFSQMEKSTKKTSFKNRENCELSDHCIKLQKRKSNVESALSHGLKSLNRKSP
SHSSSSEDADSASELADSEGGEEYNAMMKNCLRVNLTLADLEQLAGSDLKVPNEDTKSDGPETTTQCKFDRGSKSPKTPTGLRRGRQCIR
PAEIVASLLEGEENTCGKQKPKENNLKPKFQAFKGVGCLYEKESMKKSLKDSVASNNKDQNSMKHEDPSIISMEDGSPYVNGSLGEVTPC
QHAKKANGPNYIQPQKRQTTFESQDRKAVSPSSSEKRSKNPISRPLEGKKSLSLSAKTHNIGFDKDSCHSTTKTEASQEERSDSSGLTSL
KKSPKVSSKDTREIKTDFSLSISNSSDVSAKDKHAEDNEKRLAALEARQKAKEVQKKLVHNALANLSSNQRGLNQIWNVKKQSVYLMNLR
KSGTLGHPGSLDETTYERLAEETLDSLAEFFEDLADKPYTFEDYDVSFGSGVLTVKLGGDLGTYVINKQTPNKQIWLSSPSSGPKRYDWT

--------------------------------------------------------------
>59570_59570_5_NOL8-FXN_NOL8_chr9_95076549_ENST00000545558_FXN_chr9_71661301_ENST00000396364_length(transcript)=3446nt_BP=2851nt
AGAAGTTAGGGGCTGCAGCGGCGCTGGCTTTAGGTGAACGACGTGGTGAGGAGTGGGTTTCGGGCATGAGAAGTCACAGGGCCGTTTCCT
AGTCTCTCTTCACTTCTTTGGGTCTTCTCAGAGAAAGAAGGCTGCCGTGGGTAGGCTGGGGGCGGAGACTATCGGGAAGAGGTAGGCCGA
AGTTCTGCCCAGAATACACGCCATGTGGTGGACGCTGGTTGGGAGTCTCTTCTGGAAAGAGTCTGTCAGCTCTTGGGGAAGGGAAGGGCG
AGAGCTGAGCGCCTGCCGGGTGCTAAACGAAATGAGAGATACTATGATGGGCCCTAGTACCTCTGGAAAAGTTTTCCTGAGTCCCCTGTG
ATACAGCAACCTTCATAGTATAGTGTTAAGAATTCCAAGTTCTGAAGGTAGACCTGCATTATAATCCTGGATTCACTAATTTTCGAAAAT
TACTTTTCCCACTGAAACACACCCAAGTATATGCCCAGCCTTCATGAAAGTGAACAGAGAAACGAAGCGCCTTTATGTGGGTGGCCTTAG
CCAGGACATTTCTGAGGCAGACCTACAAAATCAGTTCAGCAGATTTGGAGAAGTTTCGGATGTGGAGATCATCACACGGAAAGATGACCA
AGGAAACCCACAGAAAGTTTTTGCATATATCAACATCAGTGTAGCAGAAGCGGACCTGAAAAAATGTATGTCTGTTTTAAATAAAACAAA
ATGGAAAGGTGGAACATTACAAATTCAACTAGCAAAAGAAAGCTTTCTGCACAGATTGGCCCAAGAGAGAGAAGCAGCAAAAGCTAAGAA
AGAAGAATCAACAACAGGTAACGCCAACTTGTTAGAAAAGACAGGAGGAGTGGATTTCCATATGAAAGCTGTGCCAGGGACAGAAGTGCC
AGGGCATAAGAATTGGGTTGTGAGCAAATTTGGAAGAGTCTTACCTGTTCTTCACCTTAAAAATCAACATAAACGTAAAATCATCAAATA
TGATCCCTCAAAATACTGCCACAACCTGAAGAAGATAGGGGAGGATTTCTCAAACACCATTCCTATATCCAGCCTGACTTGGGAATTAGA
AGGAGGGAATGACCCTATGAGTAAGAAACGGCGAGGAGAGTTCTCTGACTTTCATGGCCCTCCCAAGAAGATAATAAAAGTGCAGAAGGA
TGAGAGTTCCACTGGGTCTCTGGCCATGAGTACAAGGCCCAGGAGGGTAATAGAGAGACCACCCTTAACACAGCAACAGGCTGCACAAAA
AAGAACTTGTGATTCCATTACTCCTTCTAAATCATCTCCTGTACCTGTTTCTGATACTCAGAAACTTAAAAATCTACCTTTTAAGACTTC
TGGCTTGGAAACTGCCAAGAAGAGAAACAGCATTTCTGATGATGATACTGATTCTGAAGATGAATTGAGAATGATGATTGCGAAAGAGGA
AAACTTACAGAGAACTACACAACCCTCAATAAATGAATCTGAAAGTGATCCTTTTGAAGTTGTAAGGGATGATTTCAAATCAGGCGTTCA
CAAACTGCATTCTTTAATAGGTTTAGGTATCAAAAATCGTGTCTCTTGCCATGATAGTGATGATGATATTATGAGAAATGATCGTGAGTA
TGACTCAGGAGATACAGATGAAATTATTGCGATGAAAAAAAATGTTGCTAAGGTCAAAAACAGTACAGAATTTTCACAAATGGAAAAATC
TACGAAGAAAACTTCTTTCAAAAATAGAGAAAACTGTGAGCTTTCTGATCACTGTATTAAACTACAAAAAAGAAAAAGCAATGTAGAGTC
AGCCCTCAGTCATGGATTAAAGTCTCTTAATCGTAAATCTCCCTCTCACTCCAGTAGCAGTGAAGATGCTGATTCTGCATCAGAATTAGC
TGACTCTGAAGGAGGTGAGGAGTATAATGCCATGATGAAAAACTGCCTTCGTGTGAATCTCACTTTAGCTGATTTGGAACAATTGGCTGG
CAGTGATCTGAAGGTTCCAAATGAAGATACTAAGAGTGATGGACCAGAAACCACCACCCAATGCAAGTTTGACAGAGGCTCCAAGAGCCC
CAAGACTCCCACTGGCCTCCGCAGAGGCCGACAGTGTATTCGTCCTGCGGAGATTGTGGCTTCCCTGTTAGAAGGAGAGGAGAACACCTG
TGGCAAACAGAAACCAAAGGAAAACAATTTAAAGCCAAAATTTCAGGCTTTCAAGGGAGTAGGCTGTCTATATGAAAAGGAGTCAATGAA
AAAATCCTTGAAAGACAGTGTTGCCTCTAACAATAAAGATCAGAATTCCATGAAACATGAGGATCCCAGTATCATATCCATGGAAGATGG
GTCCCCATATGTTAATGGCTCATTAGGTGAAGTGACTCCATGCCAACATGCAAAGAAGGCGAATGGCCCAAACTATATTCAGCCTCAAAA
AAGACAGACCACTTTTGAAAGCCAGGATCGCAAGGCAGTGTCCCCTAGCAGTTCTGAAAAGAGAAGTAAGAATCCTATTTCTAGGCCATT
AGAAGGTAAGAAGTCCTTAAGTCTTAGTGCAAAGACTCACAACATAGGCTTTGACAAAGACAGCTGCCATAGTACCACAAAGACAGAAGC
TTCACAGGAAGAGCGGTCTGATTCAAGCGGCCTCACATCTCTCAAGAAATCACCAAAGGTCTCATCCAAGGACACTCGGGAAATCAAAAC
TGATTTCTCACTTTCTATTAGTAATTCGTCAGATGTGAGTGCTAAAGATAAGCATGCTGAAGACAATGAGAAGCGTTTGGCAGCCTTGGA
AGCGAGGCAAAAAGCAAAAGAAGTGCAGAAGAAGCTGGTGCATAATGCTCTGGCAAATTTGAGTTCGAACCAACGTGGCCTCAACCAGAT
TTGGAATGTCAAAAAGCAGAGTGTCTATTTGATGAATTTGAGGAAATCTGGAACTTTGGGCCACCCAGGCTCTCTAGATGAGACCACCTA
TGAAAGACTAGCAGAGGAAACGCTGGACTCTTTAGCAGAGTTTTTTGAAGACCTTGCAGACAAGCCATACACGTTTGAGGACTATGATGT
CTCCTTTGGGAGTGGTGTCTTAACTGTCAAACTGGGTGGAGATCTAGGAACCTATGTGATCAACAAGCAGACGCCAAACAAGCAAATCTG
GCTATCTTCTCCATCCAGGTTAACGTGGCTCCTGTGGCTGTTCCATCCCTGAGGAAAAGTGAGGACCATGCTCTCCAAACAGGCCATGTG
CTGGACTACCTCTGTTTCTGTCTCCTGGGATTCCAATCAGCAAGTGAGCAACGAAGCAACCCAGACAGTGTGGTTCATAGGATGGCTGGG
TAAGTGGCTGTTTGTTTTTTCCTTACTGTGGATATGTATCAGTGAAGGAATCTGTAGAACATTCTTGATGGGAACATTTAGTCATATCAA

>59570_59570_5_NOL8-FXN_NOL8_chr9_95076549_ENST00000545558_FXN_chr9_71661301_ENST00000396364_length(amino acids)=902AA_BP=786
MKVNRETKRLYVGGLSQDISEADLQNQFSRFGEVSDVEIITRKDDQGNPQKVFAYINISVAEADLKKCMSVLNKTKWKGGTLQIQLAKES
FLHRLAQEREAAKAKKEESTTGNANLLEKTGGVDFHMKAVPGTEVPGHKNWVVSKFGRVLPVLHLKNQHKRKIIKYDPSKYCHNLKKIGE
DFSNTIPISSLTWELEGGNDPMSKKRRGEFSDFHGPPKKIIKVQKDESSTGSLAMSTRPRRVIERPPLTQQQAAQKRTCDSITPSKSSPV
PVSDTQKLKNLPFKTSGLETAKKRNSISDDDTDSEDELRMMIAKEENLQRTTQPSINESESDPFEVVRDDFKSGVHKLHSLIGLGIKNRV
SCHDSDDDIMRNDREYDSGDTDEIIAMKKNVAKVKNSTEFSQMEKSTKKTSFKNRENCELSDHCIKLQKRKSNVESALSHGLKSLNRKSP
SHSSSSEDADSASELADSEGGEEYNAMMKNCLRVNLTLADLEQLAGSDLKVPNEDTKSDGPETTTQCKFDRGSKSPKTPTGLRRGRQCIR
PAEIVASLLEGEENTCGKQKPKENNLKPKFQAFKGVGCLYEKESMKKSLKDSVASNNKDQNSMKHEDPSIISMEDGSPYVNGSLGEVTPC
QHAKKANGPNYIQPQKRQTTFESQDRKAVSPSSSEKRSKNPISRPLEGKKSLSLSAKTHNIGFDKDSCHSTTKTEASQEERSDSSGLTSL
KKSPKVSSKDTREIKTDFSLSISNSSDVSAKDKHAEDNEKRLAALEARQKAKEVQKKLVHNALANLSSNQRGLNQIWNVKKQSVYLMNLR
KSGTLGHPGSLDETTYERLAEETLDSLAEFFEDLADKPYTFEDYDVSFGSGVLTVKLGGDLGTYVINKQTPNKQIWLSSPSRLTWLLWLF

--------------------------------------------------------------
>59570_59570_6_NOL8-FXN_NOL8_chr9_95076549_ENST00000545558_FXN_chr9_71661301_ENST00000396366_length(transcript)=3587nt_BP=2851nt
AGAAGTTAGGGGCTGCAGCGGCGCTGGCTTTAGGTGAACGACGTGGTGAGGAGTGGGTTTCGGGCATGAGAAGTCACAGGGCCGTTTCCT
AGTCTCTCTTCACTTCTTTGGGTCTTCTCAGAGAAAGAAGGCTGCCGTGGGTAGGCTGGGGGCGGAGACTATCGGGAAGAGGTAGGCCGA
AGTTCTGCCCAGAATACACGCCATGTGGTGGACGCTGGTTGGGAGTCTCTTCTGGAAAGAGTCTGTCAGCTCTTGGGGAAGGGAAGGGCG
AGAGCTGAGCGCCTGCCGGGTGCTAAACGAAATGAGAGATACTATGATGGGCCCTAGTACCTCTGGAAAAGTTTTCCTGAGTCCCCTGTG
ATACAGCAACCTTCATAGTATAGTGTTAAGAATTCCAAGTTCTGAAGGTAGACCTGCATTATAATCCTGGATTCACTAATTTTCGAAAAT
TACTTTTCCCACTGAAACACACCCAAGTATATGCCCAGCCTTCATGAAAGTGAACAGAGAAACGAAGCGCCTTTATGTGGGTGGCCTTAG
CCAGGACATTTCTGAGGCAGACCTACAAAATCAGTTCAGCAGATTTGGAGAAGTTTCGGATGTGGAGATCATCACACGGAAAGATGACCA
AGGAAACCCACAGAAAGTTTTTGCATATATCAACATCAGTGTAGCAGAAGCGGACCTGAAAAAATGTATGTCTGTTTTAAATAAAACAAA
ATGGAAAGGTGGAACATTACAAATTCAACTAGCAAAAGAAAGCTTTCTGCACAGATTGGCCCAAGAGAGAGAAGCAGCAAAAGCTAAGAA
AGAAGAATCAACAACAGGTAACGCCAACTTGTTAGAAAAGACAGGAGGAGTGGATTTCCATATGAAAGCTGTGCCAGGGACAGAAGTGCC
AGGGCATAAGAATTGGGTTGTGAGCAAATTTGGAAGAGTCTTACCTGTTCTTCACCTTAAAAATCAACATAAACGTAAAATCATCAAATA
TGATCCCTCAAAATACTGCCACAACCTGAAGAAGATAGGGGAGGATTTCTCAAACACCATTCCTATATCCAGCCTGACTTGGGAATTAGA
AGGAGGGAATGACCCTATGAGTAAGAAACGGCGAGGAGAGTTCTCTGACTTTCATGGCCCTCCCAAGAAGATAATAAAAGTGCAGAAGGA
TGAGAGTTCCACTGGGTCTCTGGCCATGAGTACAAGGCCCAGGAGGGTAATAGAGAGACCACCCTTAACACAGCAACAGGCTGCACAAAA
AAGAACTTGTGATTCCATTACTCCTTCTAAATCATCTCCTGTACCTGTTTCTGATACTCAGAAACTTAAAAATCTACCTTTTAAGACTTC
TGGCTTGGAAACTGCCAAGAAGAGAAACAGCATTTCTGATGATGATACTGATTCTGAAGATGAATTGAGAATGATGATTGCGAAAGAGGA
AAACTTACAGAGAACTACACAACCCTCAATAAATGAATCTGAAAGTGATCCTTTTGAAGTTGTAAGGGATGATTTCAAATCAGGCGTTCA
CAAACTGCATTCTTTAATAGGTTTAGGTATCAAAAATCGTGTCTCTTGCCATGATAGTGATGATGATATTATGAGAAATGATCGTGAGTA
TGACTCAGGAGATACAGATGAAATTATTGCGATGAAAAAAAATGTTGCTAAGGTCAAAAACAGTACAGAATTTTCACAAATGGAAAAATC
TACGAAGAAAACTTCTTTCAAAAATAGAGAAAACTGTGAGCTTTCTGATCACTGTATTAAACTACAAAAAAGAAAAAGCAATGTAGAGTC
AGCCCTCAGTCATGGATTAAAGTCTCTTAATCGTAAATCTCCCTCTCACTCCAGTAGCAGTGAAGATGCTGATTCTGCATCAGAATTAGC
TGACTCTGAAGGAGGTGAGGAGTATAATGCCATGATGAAAAACTGCCTTCGTGTGAATCTCACTTTAGCTGATTTGGAACAATTGGCTGG
CAGTGATCTGAAGGTTCCAAATGAAGATACTAAGAGTGATGGACCAGAAACCACCACCCAATGCAAGTTTGACAGAGGCTCCAAGAGCCC
CAAGACTCCCACTGGCCTCCGCAGAGGCCGACAGTGTATTCGTCCTGCGGAGATTGTGGCTTCCCTGTTAGAAGGAGAGGAGAACACCTG
TGGCAAACAGAAACCAAAGGAAAACAATTTAAAGCCAAAATTTCAGGCTTTCAAGGGAGTAGGCTGTCTATATGAAAAGGAGTCAATGAA
AAAATCCTTGAAAGACAGTGTTGCCTCTAACAATAAAGATCAGAATTCCATGAAACATGAGGATCCCAGTATCATATCCATGGAAGATGG
GTCCCCATATGTTAATGGCTCATTAGGTGAAGTGACTCCATGCCAACATGCAAAGAAGGCGAATGGCCCAAACTATATTCAGCCTCAAAA
AAGACAGACCACTTTTGAAAGCCAGGATCGCAAGGCAGTGTCCCCTAGCAGTTCTGAAAAGAGAAGTAAGAATCCTATTTCTAGGCCATT
AGAAGGTAAGAAGTCCTTAAGTCTTAGTGCAAAGACTCACAACATAGGCTTTGACAAAGACAGCTGCCATAGTACCACAAAGACAGAAGC
TTCACAGGAAGAGCGGTCTGATTCAAGCGGCCTCACATCTCTCAAGAAATCACCAAAGGTCTCATCCAAGGACACTCGGGAAATCAAAAC
TGATTTCTCACTTTCTATTAGTAATTCGTCAGATGTGAGTGCTAAAGATAAGCATGCTGAAGACAATGAGAAGCGTTTGGCAGCCTTGGA
AGCGAGGCAAAAAGCAAAAGAAGTGCAGAAGAAGCTGGTGCATAATGCTCTGGCAAATTTGAGTTCGAACCAACGTGGCCTCAACCAGAT
TTGGAATGTCAAAAAGCAGAGTGTCTATTTGATGAATTTGAGGAAATCTGGAACTTTGGGCCACCCAGGCTCTCTAGATGAGACCACCTA
TGAAAGACTAGCAGAGGAAACGCTGGACTCTTTAGCAGAGTTTTTTGAAGACCTTGCAGACAAGCCATACACGTTTGAGGACTATGATGT
CTCCTTTGGGAGTGGTGTCTTAACTGTCAAACTGGGTGGAGATCTAGGAACCTATGTGATCAACAAGCAGACGCCAAACAAGCAAATCTG
GCTATCTTCTCCATCCAGGTATGTAGTGGACCTAAGCGTTATGACTGGACTGGGAAAAACTGGGTGTACTCCCACGACGGCGTGTCCCTC
CATGAGCTGCTGGCCGCAGAGCTCACTAAAGCCTTAAAAACCAAACTGGACTTGTCTTCCTTGGCCTATTCCGGAAAAGATGCTTGATGC
CCAGCCCCGTTTTAAGGACATTAAAAGCTATCAGGCCAAGACCCCAGCTTCATTATGCAGCTGAGGTCTGTTTTTTGTTGTTGTTGTTGT
TTATTTTTTTTATTCCTGCTTTTGAGGACAGTTGGGCTATGTGTCACAGCTCTGTAGAAAGAATGTGTTGCCTCCTACCTTGCCCCCAAG

>59570_59570_6_NOL8-FXN_NOL8_chr9_95076549_ENST00000545558_FXN_chr9_71661301_ENST00000396366_length(amino acids)=927AA_BP=786
MKVNRETKRLYVGGLSQDISEADLQNQFSRFGEVSDVEIITRKDDQGNPQKVFAYINISVAEADLKKCMSVLNKTKWKGGTLQIQLAKES
FLHRLAQEREAAKAKKEESTTGNANLLEKTGGVDFHMKAVPGTEVPGHKNWVVSKFGRVLPVLHLKNQHKRKIIKYDPSKYCHNLKKIGE
DFSNTIPISSLTWELEGGNDPMSKKRRGEFSDFHGPPKKIIKVQKDESSTGSLAMSTRPRRVIERPPLTQQQAAQKRTCDSITPSKSSPV
PVSDTQKLKNLPFKTSGLETAKKRNSISDDDTDSEDELRMMIAKEENLQRTTQPSINESESDPFEVVRDDFKSGVHKLHSLIGLGIKNRV
SCHDSDDDIMRNDREYDSGDTDEIIAMKKNVAKVKNSTEFSQMEKSTKKTSFKNRENCELSDHCIKLQKRKSNVESALSHGLKSLNRKSP
SHSSSSEDADSASELADSEGGEEYNAMMKNCLRVNLTLADLEQLAGSDLKVPNEDTKSDGPETTTQCKFDRGSKSPKTPTGLRRGRQCIR
PAEIVASLLEGEENTCGKQKPKENNLKPKFQAFKGVGCLYEKESMKKSLKDSVASNNKDQNSMKHEDPSIISMEDGSPYVNGSLGEVTPC
QHAKKANGPNYIQPQKRQTTFESQDRKAVSPSSSEKRSKNPISRPLEGKKSLSLSAKTHNIGFDKDSCHSTTKTEASQEERSDSSGLTSL
KKSPKVSSKDTREIKTDFSLSISNSSDVSAKDKHAEDNEKRLAALEARQKAKEVQKKLVHNALANLSSNQRGLNQIWNVKKQSVYLMNLR
KSGTLGHPGSLDETTYERLAEETLDSLAEFFEDLADKPYTFEDYDVSFGSGVLTVKLGGDLGTYVINKQTPNKQIWLSSPSRYVVDLSVM

--------------------------------------------------------------

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Fusion Gene PPI Analysis for NOL8-FXN


check button Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in

ChiPPI page.


check button Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160)
HgeneHgene's interactorsTgeneTgene's interactors


check button - Retained PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenStill interaction with


check button - Lost PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


check button - Retained PPIs, but lost function due to frame-shift fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


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Related Drugs for NOL8-FXN


check button Drugs targeting genes involved in this fusion gene.
(DrugBank Version 5.1.8 2021-05-08)
PartnerGeneUniProtAccDrugBank IDDrug nameDrug activityDrug typeDrug status

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Related Diseases for NOL8-FXN


check button Diseases associated with fusion partners.
(DisGeNet 4.0)
PartnerGeneDisease IDDisease name# pubmedsSource