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Center for Computational Systems Medicine
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Fusion Gene Summary

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Fusion Gene ORF analysis

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Fusion Genomic Features

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Fusion Protein Features

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Fusion Gene Sequence

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Fusion Gene PPI analysis

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Related Drugs

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Related Diseases

Fusion gene:NOP56-LDLRAD4 (FusionGDB2 ID:59639)

Fusion Gene Summary for NOP56-LDLRAD4

check button Fusion gene summary
Fusion gene informationFusion gene name: NOP56-LDLRAD4
Fusion gene ID: 59639
HgeneTgene
Gene symbol

NOP56

LDLRAD4

Gene ID

10528

753

Gene nameNOP56 ribonucleoproteinlow density lipoprotein receptor class A domain containing 4
SynonymsNOL5A|SCA36C18orf1
Cytomap

20p13

18p11.21

Type of geneprotein-codingprotein-coding
Descriptionnucleolar protein 56NOP56 ribonucleoprotein homolognucleolar protein 5A (56kDa with KKE/D repeat)low-density lipoprotein receptor class A domain-containing protein 4clone 22
Modification date2020031320200320
UniProtAcc

O00567

O15165

Ensembl transtripts involved in fusion geneENST00000329276, ENST00000492135, 
ENST00000585931, ENST00000586765, 
ENST00000590308, ENST00000592991, 
ENST00000359446, ENST00000361205, 
ENST00000399848, ENST00000587757, 
Fusion gene scores* DoF score8 X 5 X 5=20022 X 20 X 7=3080
# samples 824
** MAII scorelog2(8/200*10)=-1.32192809488736
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0		log2(24/3080*10)=-3.68182403997374
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0
Context

PubMed: NOP56 [Title/Abstract] AND LDLRAD4 [Title/Abstract] AND fusion [Title/Abstract]

Most frequent breakpointNOP56(2634039)-LDLRAD4(13621116), # samples:1
Anticipated loss of major functional domain due to fusion event.
* DoF score (Degree of Frequency) = # partners X # break points X # cancer types
** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)

check button Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez
PartnerGeneGO IDGO termPubMed ID
TgeneLDLRAD4

GO:0010991

negative regulation of SMAD protein complex assembly

24627487


check buttonFusion gene breakpoints across NOP56 (5'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check buttonFusion gene breakpoints across LDLRAD4 (3'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check button Fusion gene information from two resources (ChiTars 5.0 and ChimerDB 4.0)
* All genome coordinats were lifted-over on hg19.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
SourceDiseaseSampleHgeneHchrHbpHstrandTgeneTchrTbpTstrand
ChimerDB4GBMTCGA-06-0238-01ANOP56chr20

2634039

+LDLRAD4chr18

13621116

+


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Fusion Gene ORF analysis for NOP56-LDLRAD4

check button Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
ORFHenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrand
5CDS-5UTRENST00000329276ENST00000585931NOP56chr20

2634039

+LDLRAD4chr18

13621116

+
5CDS-5UTRENST00000329276ENST00000586765NOP56chr20

2634039

+LDLRAD4chr18

13621116

+
5CDS-intronENST00000329276ENST00000590308NOP56chr20

2634039

+LDLRAD4chr18

13621116

+
5CDS-intronENST00000329276ENST00000592991NOP56chr20

2634039

+LDLRAD4chr18

13621116

+
In-frameENST00000329276ENST00000359446NOP56chr20

2634039

+LDLRAD4chr18

13621116

+
In-frameENST00000329276ENST00000361205NOP56chr20

2634039

+LDLRAD4chr18

13621116

+
In-frameENST00000329276ENST00000399848NOP56chr20

2634039

+LDLRAD4chr18

13621116

+
In-frameENST00000329276ENST00000587757NOP56chr20

2634039

+LDLRAD4chr18

13621116

+
intron-3CDSENST00000492135ENST00000359446NOP56chr20

2634039

+LDLRAD4chr18

13621116

+
intron-3CDSENST00000492135ENST00000361205NOP56chr20

2634039

+LDLRAD4chr18

13621116

+
intron-3CDSENST00000492135ENST00000399848NOP56chr20

2634039

+LDLRAD4chr18

13621116

+
intron-3CDSENST00000492135ENST00000587757NOP56chr20

2634039

+LDLRAD4chr18

13621116

+
intron-5UTRENST00000492135ENST00000585931NOP56chr20

2634039

+LDLRAD4chr18

13621116

+
intron-5UTRENST00000492135ENST00000586765NOP56chr20

2634039

+LDLRAD4chr18

13621116

+
intron-intronENST00000492135ENST00000590308NOP56chr20

2634039

+LDLRAD4chr18

13621116

+
intron-intronENST00000492135ENST00000592991NOP56chr20

2634039

+LDLRAD4chr18

13621116

+

check buttonORFfinder result based on the fusion transcript sequence of in-frame fusion genes.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandSeq length
(transcript)		BP loci
(transcript)		Predicted start
(transcript)		Predicted stop
(transcript)		Seq length
(amino acids)
ENST00000329276NOP56chr202634039+ENST00000361205LDLRAD4chr1813621116+85617245161463315
ENST00000329276NOP56chr202634039+ENST00000399848LDLRAD4chr1813621116+85087245161409297
ENST00000329276NOP56chr202634039+ENST00000359446LDLRAD4chr1813621116+85617245161463315
ENST00000329276NOP56chr202634039+ENST00000587757LDLRAD4chr1813621116+15847245161463315

check buttonDeepORF prediction of the coding potential based on the fusion transcript sequence of in-frame fusion genes. DeepORF is a coding potential classifier based on convolutional neural network by comparing the real Ribo-seq data. If the no-coding score < 0.5 and coding score > 0.5, then the in-frame fusion transcript is predicted as being likely translated.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandNo-coding scoreCoding score
ENST00000329276ENST00000361205NOP56chr202634039+LDLRAD4chr1813621116+0.0005038950.9994961
ENST00000329276ENST00000399848NOP56chr202634039+LDLRAD4chr1813621116+0.0005058710.9994941
ENST00000329276ENST00000359446NOP56chr202634039+LDLRAD4chr1813621116+0.0005038950.9994961
ENST00000329276ENST00000587757NOP56chr202634039+LDLRAD4chr1813621116+0.0087592390.9912408

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Fusion Genomic Features for NOP56-LDLRAD4


check buttonFusionAI prediction of the potential fusion gene breakpoint based on the pre-mature RNA sequence context (+/- 5kb of individual partner genes, total 20kb length sequence). FusionAI is a fusion gene breakpoint classifier based on convolutional neural network by comparing the fusion positive and negative sequence context of ~ 20K fusion gene data. From here, we can have the relative potentency of the 20K genomic sequence how individual sequnce will be likely used as the gene fusion breakpoints.
HgeneHchrHbpHstrandTgeneTchrTbpTstrand1-pp (fusion gene breakpoint)
NOP56chr202634039+LDLRAD4chr1813621115+3.58E-101
NOP56chr202634039+LDLRAD4chr1813621115+3.58E-101

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions. We integrated a total of 44 different types of human genomic feature loci information across five big categories including virus integration sites, repeats, structural variants, chromatin states, and gene expression regulation. More details are in help page.
genomic feature

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions that are ovelapped with the top 1% feature importance score regions. More details are in help page.
genomic feature of top 1%

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Fusion Protein Features for NOP56-LDLRAD4


check button Four levels of functional features of fusion genes
Go to FGviewer search page for the most frequent breakpoint (https://ccsmweb.uth.edu/FGviewer/chr20:2634039/chr18:13621116)
- FGviewer provides the online visualization of the retention search of the protein functional features across DNA, RNA, protein, and pathological levels.
- How to search
1. Put your fusion gene symbol.
2. Press the tab key until there will be shown the breakpoint information filled.
4. Go down and press 'Search' tab twice.
4. Go down to have the hyperlink of the search result.
5. Click the hyperlink.
6. See the FGviewer result for your fusion gene.
FGviewer

check buttonMain function of each fusion partner protein. (from UniProt)
HgeneTgene
NOP56

O00567

LDLRAD4

O15165

FUNCTION: Involved in the early to middle stages of 60S ribosomal subunit biogenesis. Core component of box C/D small nucleolar ribonucleoprotein (snoRNP) particles. Required for the biogenesis of box C/D snoRNAs such U3, U8 and U14 snoRNAs. {ECO:0000269|PubMed:12777385, ECO:0000269|PubMed:15574333}.FUNCTION: Functions as a negative regulator of TGF-beta signaling and thereby probably plays a role in cell proliferation, differentiation, apoptosis, motility, extracellular matrix production and immunosuppression. In the canonical TGF-beta pathway, ZFYVE9/SARA recruits the intracellular signal transducer and transcriptional modulators SMAD2 and SMAD3 to the TGF-beta receptor. Phosphorylated by the receptor, SMAD2 and SMAD3 then form a heteromeric complex with SMAD4 that translocates to the nucleus to regulate transcription. Through interaction with SMAD2 and SMAD3, LDLRAD4 may compete with ZFYVE9 and SMAD4 and prevent propagation of the intracellular signal. {ECO:0000269|PubMed:24627487}.

check buttonRetention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at

download page


* Minus value of BPloci means that the break pointn is located before the CDS.
- In-frame and retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
TgeneLDLRAD4chr20:2634039chr18:13621116ENST000005859310416_480230.0DomainLDL-receptor class A
TgeneLDLRAD4chr20:2634039chr18:13621116ENST0000035944626180_18360307.0MotifNote=PPxY motif 1
TgeneLDLRAD4chr20:2634039chr18:13621116ENST0000035944626252_25560307.0MotifNote=PPxY motif 2
TgeneLDLRAD4chr20:2634039chr18:13621116ENST0000036120537180_18360307.0MotifNote=PPxY motif 1
TgeneLDLRAD4chr20:2634039chr18:13621116ENST0000036120537252_25560307.0MotifNote=PPxY motif 2
TgeneLDLRAD4chr20:2634039chr18:13621116ENST0000039984836180_18360289.0MotifNote=PPxY motif 1
TgeneLDLRAD4chr20:2634039chr18:13621116ENST0000039984836252_25560289.0MotifNote=PPxY motif 2
TgeneLDLRAD4chr20:2634039chr18:13621116ENST0000058593104180_1830230.0MotifNote=PPxY motif 1
TgeneLDLRAD4chr20:2634039chr18:13621116ENST0000058593104252_2550230.0MotifNote=PPxY motif 2
TgeneLDLRAD4chr20:2634039chr18:13621116ENST0000058676503180_18323252.0MotifNote=PPxY motif 1
TgeneLDLRAD4chr20:2634039chr18:13621116ENST0000058676503252_25523252.0MotifNote=PPxY motif 2
TgeneLDLRAD4chr20:2634039chr18:13621116ENST0000058775704180_18323270.0MotifNote=PPxY motif 1
TgeneLDLRAD4chr20:2634039chr18:13621116ENST0000058775704252_25523270.0MotifNote=PPxY motif 2
TgeneLDLRAD4chr20:2634039chr18:13621116ENST000003594462686_30660307.0Topological domainCytoplasmic
TgeneLDLRAD4chr20:2634039chr18:13621116ENST000003612053786_30660307.0Topological domainCytoplasmic
TgeneLDLRAD4chr20:2634039chr18:13621116ENST000003998483686_30660289.0Topological domainCytoplasmic
TgeneLDLRAD4chr20:2634039chr18:13621116ENST00000585931041_640230.0Topological domainLumenal
TgeneLDLRAD4chr20:2634039chr18:13621116ENST000005859310486_3060230.0Topological domainCytoplasmic
TgeneLDLRAD4chr20:2634039chr18:13621116ENST000005867650386_30623252.0Topological domainCytoplasmic
TgeneLDLRAD4chr20:2634039chr18:13621116ENST000005877570486_30623270.0Topological domainCytoplasmic
TgeneLDLRAD4chr20:2634039chr18:13621116ENST000003594462665_8560307.0TransmembraneHelical
TgeneLDLRAD4chr20:2634039chr18:13621116ENST000003612053765_8560307.0TransmembraneHelical
TgeneLDLRAD4chr20:2634039chr18:13621116ENST000003998483665_8560289.0TransmembraneHelical
TgeneLDLRAD4chr20:2634039chr18:13621116ENST000005859310465_850230.0TransmembraneHelical
TgeneLDLRAD4chr20:2634039chr18:13621116ENST000005867650365_8523252.0TransmembraneHelical
TgeneLDLRAD4chr20:2634039chr18:13621116ENST000005877570465_8523270.0TransmembraneHelical

- In-frame and not-retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneNOP56chr20:2634039chr18:13621116ENST00000329276+312438_58969595.0Compositional biasNote=Lys-rich
HgeneNOP56chr20:2634039chr18:13621116ENST00000329276+312292_41069595.0DomainNop
TgeneLDLRAD4chr20:2634039chr18:13621116ENST000003594462616_4860307.0DomainLDL-receptor class A
TgeneLDLRAD4chr20:2634039chr18:13621116ENST000003612053716_4860307.0DomainLDL-receptor class A
TgeneLDLRAD4chr20:2634039chr18:13621116ENST000003998483616_4860289.0DomainLDL-receptor class A
TgeneLDLRAD4chr20:2634039chr18:13621116ENST000005867650316_4823252.0DomainLDL-receptor class A
TgeneLDLRAD4chr20:2634039chr18:13621116ENST000005877570416_4823270.0DomainLDL-receptor class A
TgeneLDLRAD4chr20:2634039chr18:13621116ENST00000359446261_6460307.0Topological domainLumenal
TgeneLDLRAD4chr20:2634039chr18:13621116ENST00000361205371_6460307.0Topological domainLumenal
TgeneLDLRAD4chr20:2634039chr18:13621116ENST00000399848361_6460289.0Topological domainLumenal
TgeneLDLRAD4chr20:2634039chr18:13621116ENST00000586765031_6423252.0Topological domainLumenal
TgeneLDLRAD4chr20:2634039chr18:13621116ENST00000587757041_6423270.0Topological domainLumenal


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Fusion Gene Sequence for NOP56-LDLRAD4


check button For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. To have fusion amino acid sequence, we ran ORFfinder and chose the longest ORF among the all predicted ones.
>59639_59639_1_NOP56-LDLRAD4_NOP56_chr20_2634039_ENST00000329276_LDLRAD4_chr18_13621116_ENST00000359446_length(transcript)=8561nt_BP=724nt
GGCTCGTCCCCGAGTAGGGGACGGGAACGCCTGGGTCCCGGGGACGTGGGGCGCAGGGTCTGGGGCCCGAGGCCACGGACGAAGCGGGAA
GCCGGCTAGGCAGCGGTCTCTGTCTGGGATGGACGCCGCGCCCCACGCGGACCTCCCGCCCCGACTTCACCCAGCTCTGCTGCCCGTAAC
TCATATGACAAGAACATCAGGAACCGGACTATTACCCCGAAAGGGCCTTCCCAAGTCGTTTCGCCGCCTGCAGTGCCCGACCGGGGGCCG
CGCGTCCCCGGCAACCACGCCCGCCCGCGCAGCTGCAGAGGCCGGAAAAGGCCCGCTCGCCCGCGCTCGGCACCACCCAGCCCGCGCTCC
GGGCGATACCACCCTGGGCGGCCCCTCCAAAGGCCGGAGATGGTGTCGTCCCCGGCCTCCGATTGGTCGGGGGGGCGGGGGCGTGGCCTC
TGGAGCCTGGTTCCGCGCGCCGGAGCGCGCTAGCCGCATTGCGAGCCGAACCCGGGAGCTGGCGCCATGGTGCTGTTGCACGTGCTGTTT
GAGCACGCGGTCGGCTACGCGCTGCTGGCGCTGAAGGAAGTGGAGGAGATCAGTCTGCTGCAGCCGCAGGTGGAGGAGTCTGTGCTCAAC
CTGGGCAAATTCCACAGCATCGTTCGTCTGGTGGCCTTTTGTCCCTTTGCCTCATCCCAGGTTGCCTTGGAAAATGCCAACGCCGTGTCT
GAAGCGGAGCTGGAGTTCGCCCAAATCATCATCATCGTCGTGGTGGTCACGGTGATGGTGGTGGTCATCGTCTGCCTGCTGAACCACTAC
AAAGTCTCCACGCGGTCCTTCATCAACCGCCCGAACCAGAGCCGGAGGCGGGAGGACGGGCTGCCGCAGGAAGGGTGCCTGTGGCCTTCA
GACAGCGCCGCACCGCGGCTGGGCGCCTCGGAGATCATGCATGCCCCGCGGTCCAGGGACAGGTTCACAGCGCCGTCCTTCATCCAGAGG
GATCGCTTCAGCCGCTTCCAGCCCACCTACCCCTATGTGCAGCACGAGATTGATCTTCCTCCCACCATCTCCCTGTCCGACGGTGAAGAG
CCACCTCCTTACCAGGGGCCCTGCACCCTGCAGCTCCGGGACCCTGAACAGCAGATGGAACTCAACCGAGAGTCCGTGAGGGCCCCACCC
AACCGAACCATATTTGACAGTGATTTAATAGACATTGCTATGTATAGCGGGGGTCCATGCCCACCCAGCAGCAACTCGGGCATCAGTGCA
AGCACCTGCAGCAGTAACGGGAGGATGGAGGGGCCACCCCCCACATACAGCGAGGTGATGGGCCACCACCCAGGCGCCTCTTTCCTCCAT
CACCAGCGCAGCAACGCACACAGGGGCAGCAGACTGCAGTTTCAGCAGAACAATGCAGAGAGCACAATAGTACCCATCAAAGGCAAAGAT
AGGAAGCCTGGGAACCTGGTCTGATTCCTTCCAACGTGCACTTCAGCTGGAGAAAGAAACCAAGAAGGGAAGCGGCCGCTGGGCCCCTCC
TGCGCACAGTGTTGTTCAGTTTCACATGGTACAAATAAGTAAAACCAAATGAGCAAACACGGTCTTTGTTTCTGATTCCTTTTAGGGGAA
TTGCATGCAAACTAGACTGAAATGATACAAACTTCCATCTGGTCTGACCGCAAACAGTGTTTATTTGGGGACAGGGGTTGGGATGGGGGT
GTGGGCAGGGGAAAACAGAGAACGGGATGCTTTGAAGATACCATGAAATAAAACCCACAGAGGTATTTGATGTATTTAATTGTGAAAGGA
GACTTTGCAGATAAATGAGGCCAGAATGGCATGTTTTATAATTAACTGAATAAAGAAGGAAGCATTATTATATATTATTGTGGGGAAGAA
CCAGCCAGTTCGCTTTTTCTCCTAAGGTGTGGAACTTTTATTTTGTTTTAAAAATATGAATCAAAATTCCTGTGTTGTGTGCCAAGGTAT
AAAGTGGAGAAGTTAGATGAGTGCAAGGAGCTCCTTTGTGTTGTGATGATGTGTTTTAAAAGTTGCACTATCTTAATGTTGAAAATATTT
ACAAGGGAACTGTTTTACGTGAAGTTCTGTATGTTGTCTTTTCACCTGTGGATTGTAATCAGGCCCAAGGAATATCCTGGAGTGGTCCCC
AGAAGCATCCAAGAAAAGATATTTGGGGACGTAGCCTAACATTTTACCAACTTACGTAAATCAAAAAAGTCATTATTGTTGCAGGAGTTT
GCATCAAATAGCAGTGCATCGCTGAAGCTTTTGGAGACTTTTGGATGGAAGATAAGATAGGGAAGATTAAGTTCCAGCATTTCTGACTTG
TTATTTTGAGTTACTCTGCTACTCTTAGGCTGCATAGTTTATGAGAAAATGAACACATGCATTTATGGATCCAGTATCATGCAGTGCTGC
CCTCATCCTCCAGCAGTGCAATTTCTTCAGTAATTTAGATTTTTTTCACTATAGCATGAAATATATTCAAATACATACCTTATTTTATGC
AATAAATTGTTTAAAATGCAAGGTGGTTATTCTGCATACTGTTGAAATATGTGACTCCTCAGTATATTCCCATTGCCTCTCCCCCTTTCC
TCGACAGCTTAGTTCAGTTCTGCAGGGCTGCTCAGTTCACAGGAGGCTCCCAGCAGCCACCCCACATCCAGCCTACACAGAACTTCGTGT
GGGAGTGGTGTGGGTGGTGGTTTCTTATGCTTTGGAAGCCCCTAGAAATAATGACGGAAGAATGCCATGTTGCTGATCGTGGTAATAAGC
CATTGTGGGTTATTGTATGTCACTAGTATTAGCATAGCATTCTTAAAGGAATGCAGTGCTCAAAACCTACCCAAATTCCCGCAGGATTCT
ACCAAACCCTTCCCCAGGCCAGCTTTTGTACTGAAGGCAAGAACTGGACAGTCAGAGAACAGTGGAGGGGGCAAGTGACTGAAGAGCACC
GGGTAAAAAGCACAACATGCAGTTAAAATGCAACTAGAAAACTAATTTTAAATATTGTTAGTTTTAATATTCCTGATATTTACAAATATT
CATTCTTATATACAATGAAAAAAATAACTTTCTTCTGCAGATGTAAGCACTGGCTTTTATAAGAGCAGCAGCCAACACGTTTAGCAGACA
CTGCGCGTGGAGAAGGGCTTATCTGCAGTACACTCTGCCATGTGGAGGGTGGGCCTCTGTGGCCTCTTCACATAACAAGATGAGCTGGAA
TGATGATTCCATGACTCCCACCTATGCAGCCTTAAAGCCAAATCCGCGTGTGTGTGTTTGTGTCTGTCTGTGGGTCTCGAAGGTGATCCG
TCGGTGCGGTGGCTCTGTGCTGTAACTGGAGAGACTGTTCCAAACCCCAAGAGTTGTCTGATCCTAGTCTGTTCCCTTCTGCTTCTTACC
TCTGTAGATAGGTCACTGGTTTTTGTTTGTTTGTTTTGAGGATTGGAATTTCCATTACATTCATCCTTTGCACACAGTAACATCCACAGA
ACTAGTCCAACTCTTAAAAGGAGAGAGGAAAAACACAGGCACCAGTTGTCAGCTCATGCTTACAACCTGTGTGGAAGTATATACAGTTGA
GAGTCACAGTGGAGGTTCTGAGACTGGATTCAGTCTTGTTCCAGTGACAGTTGGAAGGCCTCTGCTGGAGAGACACCAGCTCTCAGGGCA
GAGATTGGCTTGGGGCCAGAAGGACCCTCCCCAACCCTGGAGACACCCTGAAGGTTCACTGGCTCTCCAGATTAGCCTCTCTTCCTCTGT
CAGGCAAAGATGAGGAGCCCGTGTTCCCATCGGGCCCTGCTGGCAGGGACTTGCAGTGGATTCTTGGTCAGGTGTGCCCACAGATGCGGA
GGCGAGGTGAGTGATTCCATCATTTCAGTTCTCACCTGCAGTTTTGGTGAAGCAGGAGATGCACCCCACAGCTCTAGCTCTCAAATGGCT
TCACAGTCCTTACTTCTCTACCTGCCTCAAGAAGGGGCTCAGAGCAGAGACTTGTGAATTCCTTAGTAACTGTGAGTATATGAATGTGTT
GCACATGTCCACAGTATTGGCGAGATAATTACATAATTCAGATACCTTTAATCATCTTTCAAGAAAGAGGCTCCTCCCATTCAACCACCC
TAGAGAACTGCCTTTGTTAAATAGTTATTTAAAGACTCATACATATCAAACCATGACTTTGAAAGGTCTTCGAGGCTGGGGCTCTGTAAT
GAATTAGTTTAAAAGCCAAGGTCATAACATGAATTGATGGTCAATTTCCCTTCAGCAGAAGGAAAAGGTGATTTAGATCAGTAGCTCTTT
TGAAGGTTGTGGCTGACCTGTTCATACCGTGTCGCCTCATGGCTAGTGTGGCGTTGAAAGAGTAGCGACTGGGAAGATACAACTTACACA
GTGGGGCCTATTGTTCTTTCAAGAACCCTTTTTTTAGCTTATAGAACCCATGGGTCCAGTTTAGTAACGAGTGATTTAGGCAATCAATGA
TAGGTTTATAATCTTAGATTATTCCAGCAAAGTGTGGATTGCATTGTTAGGAAGAACATTTGGTGGGAATGAACACTCCTGGGCATACCG
CTGACTTTTGTCCCTTGTTCCCGGTGTAGGAGACCCAAGGCATCTTGAATCCCATCTATAAGAACACAATCTTCCAGCATACGTTTGCTT
TTTCAGAAACTCTAGCATTCTCTTTAAATACTGACGCAATCCTTAATGGAAAAGAGATTTCATGAAGCAAATTATGTATTTCAATAGTTC
TTCTATTTTTAGTGTCCAAAATTTACTAATACAGAAGCTTGACAAGCATGTCCTCACCCTCCCCACCACATAAACACATGGACACACACC
CAAGCCACAAGAAATCCCAAGAGAGCAGAAGCGAATTTTTAAAAGATTTATCGTGAGGACTGCATTTCCATTCACTAATTTTGGCTCAAA
CTTATGAGGCAGGAAATAGGGGCCAACAGTAAATGGGGGAGGCCTCCTGACACCAGCAGAGGAATTTTGTACCCAGGCGAGGACTTCTTG
AACTTCTGCGTATCTCCGTTTGATCTCTTTCACCTTTATTTCATCTTCATAAGAATGAGAAAGGCTCAAAAGGAAGCACTTTTAGAAATC
TTCTCTGACCTAGAAGAATCCATCCAAATCCCTGCCTTCCTCTCTGAACCAACAGTTCCCTTCTCTGACAGGGGCCATCCTCTATCTTCC
ATCCAGCGGCTCTTCTTTTTAGGAAGGCTCTGGTGCAGAGCACTTCAAATATGTCCTCAGGCCAGATACTGATTGCTAGTAGAGAGACAC
CCGGCACCCAGTCCGAAGCCCTCCCTCAAAGGACCGGCTCATGGCGTTGGTCACTGGCAGGCTCAGAGACATTCTGCTGTGGGCGCAGGG
AGCCCGGCCCCCCATGCAGCCATGACTGGATGCGCCCCCATCTCGGGGGCTTGCTGCACTGCTTGTTTATTGAATTTTGCTACTTAGAAT
GGCAACATTAACTTTGTGTACCATTCATTTTTTAAAAATTTTCCAAAGCTCGGCAGTGTATGAAAGAAAAAACTGGGAAAGATACTTGGT
TTCTGTTAACTTTTGTGTTGCTTGCTTAAGTGATTAAAGCCAGTGCTTGGAGCCAAGCCTTCATGCCACGAACATGCTCCACAGCCTGCC
CTTTGCTCTCCTGCTCACACTGACCAAGAATGCCGCGTGCTTGGCCTACTGAGGTGAAAGGACAATTGAATGACAGGTGGGCAAAGGGAG
AACTTCCCCTTCTTGGTGCGAGGAAAGTCACAAATTTAAAAATGTTGCTTCCAGCCCAGATCCTAAATGCTAGTTCTCAGCAGCTGCGTG
GCTTACCGTTCGCCATTTCCACCACCGCCAGCTGCCAGCACCGCTACAGATCACAGAGATGTGAACAGACAATGGAAAGCACTCTTAGCC
TTGCAGTGGTCTACATTTTTTAGGAACCAATATTTCAGCATTCTTTATTACCCGGCACGCTGTGTCCTTTGCAGAGTTCAAGTTTATGTT
ACTGCCAGGGTCAGACAGTCATTTGCTGCTGCTGCTGCTGCTGCTGCTTCTCGAACTGGATGCATTAGGAAGCTGCTGTCTGAGTGTAGG
AATGTCTTGCTAAGAAAGCAATGTCTTCCTTCATCCTTTTCTTTCTTCCCTCTGCGTGTCCTTGTTTTTGTGTAATGCGGGAGAGGGTTA
GAGCTATAGAGATTATATATACACTATCCGTGCACATTATATATATGTAGATATACCCCTATCATGTCAGAGATCTGCATGTCAGTTTTT
CAGCAACTAAGGTGCCTCATGTTCTGAGTTCAGCAGATATAGGAACCAAGCCGCCCCCTCCTGCACTTGATGCTCCCACCTTTGTTGTGC
CTCACTTAAAATGGTGCTTTTTTCAGTTGTCTGTCTTTTCTTATGTTTTTATTTGTAAGGTGCTGTATATAAGTTGAATATATTATGCAC
ATATCCTACCCAATGGGTAGAACAAAAAGTTGTTAATACTGTAATATAATGTATAGATGATACCAATTTTAACAGAAATGGCATAGAATT
TGTGAATGCCTATGTGCTTTGTCCTCTTTTGTAAGGAAATTTGCAAATGGATGCATACAGATTAAAGTCTATGTAGTTTATTTTCCTATT
AAATATCAATATTATAACACAAGAGAAAGAAGTGTGAACAAACAAGCAACAGTTTATGACCAGCGTATATATAGCAATGGAAAGTTGCAT
CTTTGCTGTGAAAACACTTTAAAGAAAATACTTTTTAAAAAATCCCACAGCTTTTTGGTTGCCACTAGACGCTTCTTATTTTAATCATTT
TAGTAATGCTCAGCTGGACCAGTGTTAGTTATATTTGAGTCAGAAAAATGTTGTTTTTCAACTTGCTTTATAATCTCCTGCATCTATCTC
CTGCTGTAGCATCACGAAGGTGTCAGGCAACAGTGAAAAGTGCACATTTTTGTTGTTGCAGAAACTGTGTCAGAGGAATAAGTAAATCAG
CCTGCAGCAGAAGACTTTGTTCAGCTCCAGAGGCATCTGTGACCGTCTGTGTCCAAGTCTCTCTGTGCCTTTTTCTTTTACAAACTGAAG
CTGTGGAGCCAATGAAGTAACAGTAGAGATTGTAGGGAAAGAATACCTCAGGAAAAACAAATACACTTACAAGAAGACCCTGTTCTTAGA
AAATGTGTTTAGTTATGGGTTAGCACTAGAAGAGACTTGGCTGTCAGCCAGCCAAGTGAAGGACCTCTCATCCATTCCCATTCATGTCCC
ATCATAATACGGACCCAAAAAGCAAACTCGGTTTTGCCATCAGTTAGAAATTACGTTTTGGATTGTATATTGTTACATCTCTCTTCCGGC
TTAGTTTTTAGTGTCTGATTGTGACCTCTGCATTTATCTTCAAATACCCTAATTTTAAAACAAAAGAACAAGAAAAGTTTATAACACCAT
GTTCACTAAAACCACGGTTGAATCTTGGGTGTGGGCATCCTTTCGAGTGTTGTCCATAAGAGCAGTTCGTGGAATTTTGCCCATCTGACC
CATATTATCAGCTTATTCTGCCACCAGAGTAGAGTCTAATAAATTCCAAAGTTTTTATTTGCTCCATGGTGTATGTTCTGACTTTGAAAA
TGTCAGATTCTATAATCATACCCCTAACATCCAGGAAACAAATGACAGATTATCTTTAAACTGAAATTGACTCTACAATGCAACCCTTAA
TGCTGAATGGATTAAAAAAGTCAGCCCTTTTAGTATCTGTTTGAAAGGGCCGTAAAAAGTTGACACTTTTGTTGTTGTGGATCCTGCGTG
TCTAGACCCACGTGTTGTTTCCATCGTATACTGTAGGGTGCACCCCTTGGGATTCATCATTAAGAACTGAGGCTCACTGTTGTCAGAAAC
AAAGCTCCCACCCCCCAGGTTCAACCTTGTGGGAGAACTGTTGAGCATGAGAATGTTCTAGACTCAGAGGTACTAAAATTTGTTACCACA
TCATTGCTTCCTTTCTACAGGACGAATTGAGGCTTAAACTTTACTGTTAATGATACTGGTTCATTTTAATGTGCTTGTTGGTATGTTGCT
ATTTTTCATTTCATAGCTTTCAAAAATCATGCTAATTGTATACTTGTCTAGTTTAAGGCTATTTTAAAATATGTACAATACTATTCACAG
CATTTAGTTCGTTTAATTTTTATTATAAAGCAATCTACTAAAAAAGTACAACTGTATTTGAACTTTTCAATAGTTGTTTGTGAGCTATGA
TAATCAAAAGTCATTAAAGTCTTTTTTAACAAACATTCGTGCTTACTTTTCAACATAATTCCCAGTTATATACAGAAAAAGATTTCCACC
TGTCACGTATCTGCCTCTTTTACCTGAGCAATGGTGTAGTTCTTAGACCTAAGGTCTGTAATTGCAATACTTTTAAAGAAAGATGTTGCT
CTAAGTGCTGTTTGTTAGTTATGAAATCAGATTTTTCTGCTTGTTCTTAATGCTGTGGTCAAACCATAGCACAAAATCATTAAAAATAAT

>59639_59639_1_NOP56-LDLRAD4_NOP56_chr20_2634039_ENST00000329276_LDLRAD4_chr18_13621116_ENST00000359446_length(amino acids)=315AA_BP=69
MVLLHVLFEHAVGYALLALKEVEEISLLQPQVEESVLNLGKFHSIVRLVAFCPFASSQVALENANAVSEAELEFAQIIIIVVVVTVMVVV
IVCLLNHYKVSTRSFINRPNQSRRREDGLPQEGCLWPSDSAAPRLGASEIMHAPRSRDRFTAPSFIQRDRFSRFQPTYPYVQHEIDLPPT
ISLSDGEEPPPYQGPCTLQLRDPEQQMELNRESVRAPPNRTIFDSDLIDIAMYSGGPCPPSSNSGISASTCSSNGRMEGPPPTYSEVMGH

--------------------------------------------------------------
>59639_59639_2_NOP56-LDLRAD4_NOP56_chr20_2634039_ENST00000329276_LDLRAD4_chr18_13621116_ENST00000361205_length(transcript)=8561nt_BP=724nt
GGCTCGTCCCCGAGTAGGGGACGGGAACGCCTGGGTCCCGGGGACGTGGGGCGCAGGGTCTGGGGCCCGAGGCCACGGACGAAGCGGGAA
GCCGGCTAGGCAGCGGTCTCTGTCTGGGATGGACGCCGCGCCCCACGCGGACCTCCCGCCCCGACTTCACCCAGCTCTGCTGCCCGTAAC
TCATATGACAAGAACATCAGGAACCGGACTATTACCCCGAAAGGGCCTTCCCAAGTCGTTTCGCCGCCTGCAGTGCCCGACCGGGGGCCG
CGCGTCCCCGGCAACCACGCCCGCCCGCGCAGCTGCAGAGGCCGGAAAAGGCCCGCTCGCCCGCGCTCGGCACCACCCAGCCCGCGCTCC
GGGCGATACCACCCTGGGCGGCCCCTCCAAAGGCCGGAGATGGTGTCGTCCCCGGCCTCCGATTGGTCGGGGGGGCGGGGGCGTGGCCTC
TGGAGCCTGGTTCCGCGCGCCGGAGCGCGCTAGCCGCATTGCGAGCCGAACCCGGGAGCTGGCGCCATGGTGCTGTTGCACGTGCTGTTT
GAGCACGCGGTCGGCTACGCGCTGCTGGCGCTGAAGGAAGTGGAGGAGATCAGTCTGCTGCAGCCGCAGGTGGAGGAGTCTGTGCTCAAC
CTGGGCAAATTCCACAGCATCGTTCGTCTGGTGGCCTTTTGTCCCTTTGCCTCATCCCAGGTTGCCTTGGAAAATGCCAACGCCGTGTCT
GAAGCGGAGCTGGAGTTCGCCCAAATCATCATCATCGTCGTGGTGGTCACGGTGATGGTGGTGGTCATCGTCTGCCTGCTGAACCACTAC
AAAGTCTCCACGCGGTCCTTCATCAACCGCCCGAACCAGAGCCGGAGGCGGGAGGACGGGCTGCCGCAGGAAGGGTGCCTGTGGCCTTCA
GACAGCGCCGCACCGCGGCTGGGCGCCTCGGAGATCATGCATGCCCCGCGGTCCAGGGACAGGTTCACAGCGCCGTCCTTCATCCAGAGG
GATCGCTTCAGCCGCTTCCAGCCCACCTACCCCTATGTGCAGCACGAGATTGATCTTCCTCCCACCATCTCCCTGTCCGACGGTGAAGAG
CCACCTCCTTACCAGGGGCCCTGCACCCTGCAGCTCCGGGACCCTGAACAGCAGATGGAACTCAACCGAGAGTCCGTGAGGGCCCCACCC
AACCGAACCATATTTGACAGTGATTTAATAGACATTGCTATGTATAGCGGGGGTCCATGCCCACCCAGCAGCAACTCGGGCATCAGTGCA
AGCACCTGCAGCAGTAACGGGAGGATGGAGGGGCCACCCCCCACATACAGCGAGGTGATGGGCCACCACCCAGGCGCCTCTTTCCTCCAT
CACCAGCGCAGCAACGCACACAGGGGCAGCAGACTGCAGTTTCAGCAGAACAATGCAGAGAGCACAATAGTACCCATCAAAGGCAAAGAT
AGGAAGCCTGGGAACCTGGTCTGATTCCTTCCAACGTGCACTTCAGCTGGAGAAAGAAACCAAGAAGGGAAGCGGCCGCTGGGCCCCTCC
TGCGCACAGTGTTGTTCAGTTTCACATGGTACAAATAAGTAAAACCAAATGAGCAAACACGGTCTTTGTTTCTGATTCCTTTTAGGGGAA
TTGCATGCAAACTAGACTGAAATGATACAAACTTCCATCTGGTCTGACCGCAAACAGTGTTTATTTGGGGACAGGGGTTGGGATGGGGGT
GTGGGCAGGGGAAAACAGAGAACGGGATGCTTTGAAGATACCATGAAATAAAACCCACAGAGGTATTTGATGTATTTAATTGTGAAAGGA
GACTTTGCAGATAAATGAGGCCAGAATGGCATGTTTTATAATTAACTGAATAAAGAAGGAAGCATTATTATATATTATTGTGGGGAAGAA
CCAGCCAGTTCGCTTTTTCTCCTAAGGTGTGGAACTTTTATTTTGTTTTAAAAATATGAATCAAAATTCCTGTGTTGTGTGCCAAGGTAT
AAAGTGGAGAAGTTAGATGAGTGCAAGGAGCTCCTTTGTGTTGTGATGATGTGTTTTAAAAGTTGCACTATCTTAATGTTGAAAATATTT
ACAAGGGAACTGTTTTACGTGAAGTTCTGTATGTTGTCTTTTCACCTGTGGATTGTAATCAGGCCCAAGGAATATCCTGGAGTGGTCCCC
AGAAGCATCCAAGAAAAGATATTTGGGGACGTAGCCTAACATTTTACCAACTTACGTAAATCAAAAAAGTCATTATTGTTGCAGGAGTTT
GCATCAAATAGCAGTGCATCGCTGAAGCTTTTGGAGACTTTTGGATGGAAGATAAGATAGGGAAGATTAAGTTCCAGCATTTCTGACTTG
TTATTTTGAGTTACTCTGCTACTCTTAGGCTGCATAGTTTATGAGAAAATGAACACATGCATTTATGGATCCAGTATCATGCAGTGCTGC
CCTCATCCTCCAGCAGTGCAATTTCTTCAGTAATTTAGATTTTTTTCACTATAGCATGAAATATATTCAAATACATACCTTATTTTATGC
AATAAATTGTTTAAAATGCAAGGTGGTTATTCTGCATACTGTTGAAATATGTGACTCCTCAGTATATTCCCATTGCCTCTCCCCCTTTCC
TCGACAGCTTAGTTCAGTTCTGCAGGGCTGCTCAGTTCACAGGAGGCTCCCAGCAGCCACCCCACATCCAGCCTACACAGAACTTCGTGT
GGGAGTGGTGTGGGTGGTGGTTTCTTATGCTTTGGAAGCCCCTAGAAATAATGACGGAAGAATGCCATGTTGCTGATCGTGGTAATAAGC
CATTGTGGGTTATTGTATGTCACTAGTATTAGCATAGCATTCTTAAAGGAATGCAGTGCTCAAAACCTACCCAAATTCCCGCAGGATTCT
ACCAAACCCTTCCCCAGGCCAGCTTTTGTACTGAAGGCAAGAACTGGACAGTCAGAGAACAGTGGAGGGGGCAAGTGACTGAAGAGCACC
GGGTAAAAAGCACAACATGCAGTTAAAATGCAACTAGAAAACTAATTTTAAATATTGTTAGTTTTAATATTCCTGATATTTACAAATATT
CATTCTTATATACAATGAAAAAAATAACTTTCTTCTGCAGATGTAAGCACTGGCTTTTATAAGAGCAGCAGCCAACACGTTTAGCAGACA
CTGCGCGTGGAGAAGGGCTTATCTGCAGTACACTCTGCCATGTGGAGGGTGGGCCTCTGTGGCCTCTTCACATAACAAGATGAGCTGGAA
TGATGATTCCATGACTCCCACCTATGCAGCCTTAAAGCCAAATCCGCGTGTGTGTGTTTGTGTCTGTCTGTGGGTCTCGAAGGTGATCCG
TCGGTGCGGTGGCTCTGTGCTGTAACTGGAGAGACTGTTCCAAACCCCAAGAGTTGTCTGATCCTAGTCTGTTCCCTTCTGCTTCTTACC
TCTGTAGATAGGTCACTGGTTTTTGTTTGTTTGTTTTGAGGATTGGAATTTCCATTACATTCATCCTTTGCACACAGTAACATCCACAGA
ACTAGTCCAACTCTTAAAAGGAGAGAGGAAAAACACAGGCACCAGTTGTCAGCTCATGCTTACAACCTGTGTGGAAGTATATACAGTTGA
GAGTCACAGTGGAGGTTCTGAGACTGGATTCAGTCTTGTTCCAGTGACAGTTGGAAGGCCTCTGCTGGAGAGACACCAGCTCTCAGGGCA
GAGATTGGCTTGGGGCCAGAAGGACCCTCCCCAACCCTGGAGACACCCTGAAGGTTCACTGGCTCTCCAGATTAGCCTCTCTTCCTCTGT
CAGGCAAAGATGAGGAGCCCGTGTTCCCATCGGGCCCTGCTGGCAGGGACTTGCAGTGGATTCTTGGTCAGGTGTGCCCACAGATGCGGA
GGCGAGGTGAGTGATTCCATCATTTCAGTTCTCACCTGCAGTTTTGGTGAAGCAGGAGATGCACCCCACAGCTCTAGCTCTCAAATGGCT
TCACAGTCCTTACTTCTCTACCTGCCTCAAGAAGGGGCTCAGAGCAGAGACTTGTGAATTCCTTAGTAACTGTGAGTATATGAATGTGTT
GCACATGTCCACAGTATTGGCGAGATAATTACATAATTCAGATACCTTTAATCATCTTTCAAGAAAGAGGCTCCTCCCATTCAACCACCC
TAGAGAACTGCCTTTGTTAAATAGTTATTTAAAGACTCATACATATCAAACCATGACTTTGAAAGGTCTTCGAGGCTGGGGCTCTGTAAT
GAATTAGTTTAAAAGCCAAGGTCATAACATGAATTGATGGTCAATTTCCCTTCAGCAGAAGGAAAAGGTGATTTAGATCAGTAGCTCTTT
TGAAGGTTGTGGCTGACCTGTTCATACCGTGTCGCCTCATGGCTAGTGTGGCGTTGAAAGAGTAGCGACTGGGAAGATACAACTTACACA
GTGGGGCCTATTGTTCTTTCAAGAACCCTTTTTTTAGCTTATAGAACCCATGGGTCCAGTTTAGTAACGAGTGATTTAGGCAATCAATGA
TAGGTTTATAATCTTAGATTATTCCAGCAAAGTGTGGATTGCATTGTTAGGAAGAACATTTGGTGGGAATGAACACTCCTGGGCATACCG
CTGACTTTTGTCCCTTGTTCCCGGTGTAGGAGACCCAAGGCATCTTGAATCCCATCTATAAGAACACAATCTTCCAGCATACGTTTGCTT
TTTCAGAAACTCTAGCATTCTCTTTAAATACTGACGCAATCCTTAATGGAAAAGAGATTTCATGAAGCAAATTATGTATTTCAATAGTTC
TTCTATTTTTAGTGTCCAAAATTTACTAATACAGAAGCTTGACAAGCATGTCCTCACCCTCCCCACCACATAAACACATGGACACACACC
CAAGCCACAAGAAATCCCAAGAGAGCAGAAGCGAATTTTTAAAAGATTTATCGTGAGGACTGCATTTCCATTCACTAATTTTGGCTCAAA
CTTATGAGGCAGGAAATAGGGGCCAACAGTAAATGGGGGAGGCCTCCTGACACCAGCAGAGGAATTTTGTACCCAGGCGAGGACTTCTTG
AACTTCTGCGTATCTCCGTTTGATCTCTTTCACCTTTATTTCATCTTCATAAGAATGAGAAAGGCTCAAAAGGAAGCACTTTTAGAAATC
TTCTCTGACCTAGAAGAATCCATCCAAATCCCTGCCTTCCTCTCTGAACCAACAGTTCCCTTCTCTGACAGGGGCCATCCTCTATCTTCC
ATCCAGCGGCTCTTCTTTTTAGGAAGGCTCTGGTGCAGAGCACTTCAAATATGTCCTCAGGCCAGATACTGATTGCTAGTAGAGAGACAC
CCGGCACCCAGTCCGAAGCCCTCCCTCAAAGGACCGGCTCATGGCGTTGGTCACTGGCAGGCTCAGAGACATTCTGCTGTGGGCGCAGGG
AGCCCGGCCCCCCATGCAGCCATGACTGGATGCGCCCCCATCTCGGGGGCTTGCTGCACTGCTTGTTTATTGAATTTTGCTACTTAGAAT
GGCAACATTAACTTTGTGTACCATTCATTTTTTAAAAATTTTCCAAAGCTCGGCAGTGTATGAAAGAAAAAACTGGGAAAGATACTTGGT
TTCTGTTAACTTTTGTGTTGCTTGCTTAAGTGATTAAAGCCAGTGCTTGGAGCCAAGCCTTCATGCCACGAACATGCTCCACAGCCTGCC
CTTTGCTCTCCTGCTCACACTGACCAAGAATGCCGCGTGCTTGGCCTACTGAGGTGAAAGGACAATTGAATGACAGGTGGGCAAAGGGAG
AACTTCCCCTTCTTGGTGCGAGGAAAGTCACAAATTTAAAAATGTTGCTTCCAGCCCAGATCCTAAATGCTAGTTCTCAGCAGCTGCGTG
GCTTACCGTTCGCCATTTCCACCACCGCCAGCTGCCAGCACCGCTACAGATCACAGAGATGTGAACAGACAATGGAAAGCACTCTTAGCC
TTGCAGTGGTCTACATTTTTTAGGAACCAATATTTCAGCATTCTTTATTACCCGGCACGCTGTGTCCTTTGCAGAGTTCAAGTTTATGTT
ACTGCCAGGGTCAGACAGTCATTTGCTGCTGCTGCTGCTGCTGCTGCTTCTCGAACTGGATGCATTAGGAAGCTGCTGTCTGAGTGTAGG
AATGTCTTGCTAAGAAAGCAATGTCTTCCTTCATCCTTTTCTTTCTTCCCTCTGCGTGTCCTTGTTTTTGTGTAATGCGGGAGAGGGTTA
GAGCTATAGAGATTATATATACACTATCCGTGCACATTATATATATGTAGATATACCCCTATCATGTCAGAGATCTGCATGTCAGTTTTT
CAGCAACTAAGGTGCCTCATGTTCTGAGTTCAGCAGATATAGGAACCAAGCCGCCCCCTCCTGCACTTGATGCTCCCACCTTTGTTGTGC
CTCACTTAAAATGGTGCTTTTTTCAGTTGTCTGTCTTTTCTTATGTTTTTATTTGTAAGGTGCTGTATATAAGTTGAATATATTATGCAC
ATATCCTACCCAATGGGTAGAACAAAAAGTTGTTAATACTGTAATATAATGTATAGATGATACCAATTTTAACAGAAATGGCATAGAATT
TGTGAATGCCTATGTGCTTTGTCCTCTTTTGTAAGGAAATTTGCAAATGGATGCATACAGATTAAAGTCTATGTAGTTTATTTTCCTATT
AAATATCAATATTATAACACAAGAGAAAGAAGTGTGAACAAACAAGCAACAGTTTATGACCAGCGTATATATAGCAATGGAAAGTTGCAT
CTTTGCTGTGAAAACACTTTAAAGAAAATACTTTTTAAAAAATCCCACAGCTTTTTGGTTGCCACTAGACGCTTCTTATTTTAATCATTT
TAGTAATGCTCAGCTGGACCAGTGTTAGTTATATTTGAGTCAGAAAAATGTTGTTTTTCAACTTGCTTTATAATCTCCTGCATCTATCTC
CTGCTGTAGCATCACGAAGGTGTCAGGCAACAGTGAAAAGTGCACATTTTTGTTGTTGCAGAAACTGTGTCAGAGGAATAAGTAAATCAG
CCTGCAGCAGAAGACTTTGTTCAGCTCCAGAGGCATCTGTGACCGTCTGTGTCCAAGTCTCTCTGTGCCTTTTTCTTTTACAAACTGAAG
CTGTGGAGCCAATGAAGTAACAGTAGAGATTGTAGGGAAAGAATACCTCAGGAAAAACAAATACACTTACAAGAAGACCCTGTTCTTAGA
AAATGTGTTTAGTTATGGGTTAGCACTAGAAGAGACTTGGCTGTCAGCCAGCCAAGTGAAGGACCTCTCATCCATTCCCATTCATGTCCC
ATCATAATACGGACCCAAAAAGCAAACTCGGTTTTGCCATCAGTTAGAAATTACGTTTTGGATTGTATATTGTTACATCTCTCTTCCGGC
TTAGTTTTTAGTGTCTGATTGTGACCTCTGCATTTATCTTCAAATACCCTAATTTTAAAACAAAAGAACAAGAAAAGTTTATAACACCAT
GTTCACTAAAACCACGGTTGAATCTTGGGTGTGGGCATCCTTTCGAGTGTTGTCCATAAGAGCAGTTCGTGGAATTTTGCCCATCTGACC
CATATTATCAGCTTATTCTGCCACCAGAGTAGAGTCTAATAAATTCCAAAGTTTTTATTTGCTCCATGGTGTATGTTCTGACTTTGAAAA
TGTCAGATTCTATAATCATACCCCTAACATCCAGGAAACAAATGACAGATTATCTTTAAACTGAAATTGACTCTACAATGCAACCCTTAA
TGCTGAATGGATTAAAAAAGTCAGCCCTTTTAGTATCTGTTTGAAAGGGCCGTAAAAAGTTGACACTTTTGTTGTTGTGGATCCTGCGTG
TCTAGACCCACGTGTTGTTTCCATCGTATACTGTAGGGTGCACCCCTTGGGATTCATCATTAAGAACTGAGGCTCACTGTTGTCAGAAAC
AAAGCTCCCACCCCCCAGGTTCAACCTTGTGGGAGAACTGTTGAGCATGAGAATGTTCTAGACTCAGAGGTACTAAAATTTGTTACCACA
TCATTGCTTCCTTTCTACAGGACGAATTGAGGCTTAAACTTTACTGTTAATGATACTGGTTCATTTTAATGTGCTTGTTGGTATGTTGCT
ATTTTTCATTTCATAGCTTTCAAAAATCATGCTAATTGTATACTTGTCTAGTTTAAGGCTATTTTAAAATATGTACAATACTATTCACAG
CATTTAGTTCGTTTAATTTTTATTATAAAGCAATCTACTAAAAAAGTACAACTGTATTTGAACTTTTCAATAGTTGTTTGTGAGCTATGA
TAATCAAAAGTCATTAAAGTCTTTTTTAACAAACATTCGTGCTTACTTTTCAACATAATTCCCAGTTATATACAGAAAAAGATTTCCACC
TGTCACGTATCTGCCTCTTTTACCTGAGCAATGGTGTAGTTCTTAGACCTAAGGTCTGTAATTGCAATACTTTTAAAGAAAGATGTTGCT
CTAAGTGCTGTTTGTTAGTTATGAAATCAGATTTTTCTGCTTGTTCTTAATGCTGTGGTCAAACCATAGCACAAAATCATTAAAAATAAT

>59639_59639_2_NOP56-LDLRAD4_NOP56_chr20_2634039_ENST00000329276_LDLRAD4_chr18_13621116_ENST00000361205_length(amino acids)=315AA_BP=69
MVLLHVLFEHAVGYALLALKEVEEISLLQPQVEESVLNLGKFHSIVRLVAFCPFASSQVALENANAVSEAELEFAQIIIIVVVVTVMVVV
IVCLLNHYKVSTRSFINRPNQSRRREDGLPQEGCLWPSDSAAPRLGASEIMHAPRSRDRFTAPSFIQRDRFSRFQPTYPYVQHEIDLPPT
ISLSDGEEPPPYQGPCTLQLRDPEQQMELNRESVRAPPNRTIFDSDLIDIAMYSGGPCPPSSNSGISASTCSSNGRMEGPPPTYSEVMGH

--------------------------------------------------------------
>59639_59639_3_NOP56-LDLRAD4_NOP56_chr20_2634039_ENST00000329276_LDLRAD4_chr18_13621116_ENST00000399848_length(transcript)=8508nt_BP=724nt
GGCTCGTCCCCGAGTAGGGGACGGGAACGCCTGGGTCCCGGGGACGTGGGGCGCAGGGTCTGGGGCCCGAGGCCACGGACGAAGCGGGAA
GCCGGCTAGGCAGCGGTCTCTGTCTGGGATGGACGCCGCGCCCCACGCGGACCTCCCGCCCCGACTTCACCCAGCTCTGCTGCCCGTAAC
TCATATGACAAGAACATCAGGAACCGGACTATTACCCCGAAAGGGCCTTCCCAAGTCGTTTCGCCGCCTGCAGTGCCCGACCGGGGGCCG
CGCGTCCCCGGCAACCACGCCCGCCCGCGCAGCTGCAGAGGCCGGAAAAGGCCCGCTCGCCCGCGCTCGGCACCACCCAGCCCGCGCTCC
GGGCGATACCACCCTGGGCGGCCCCTCCAAAGGCCGGAGATGGTGTCGTCCCCGGCCTCCGATTGGTCGGGGGGGCGGGGGCGTGGCCTC
TGGAGCCTGGTTCCGCGCGCCGGAGCGCGCTAGCCGCATTGCGAGCCGAACCCGGGAGCTGGCGCCATGGTGCTGTTGCACGTGCTGTTT
GAGCACGCGGTCGGCTACGCGCTGCTGGCGCTGAAGGAAGTGGAGGAGATCAGTCTGCTGCAGCCGCAGGTGGAGGAGTCTGTGCTCAAC
CTGGGCAAATTCCACAGCATCGTTCGTCTGGTGGCCTTTTGTCCCTTTGCCTCATCCCAGGTTGCCTTGGAAAATGCCAACGCCGTGTCT
GAAGCGGAGCTGGAGTTCGCCCAAATCATCATCATCGTCGTGGTGGTCACGGTGATGGTGGTGGTCATCGTCTGCCTGCTGAACCACTAC
AAAGTCTCCACGCGGTCCTTCATCAACCGCCCGAACCAGAGCCGGAGGCGGGAGGACGGGCTGCCGCAGATCATGCATGCCCCGCGGTCC
AGGGACAGGTTCACAGCGCCGTCCTTCATCCAGAGGGATCGCTTCAGCCGCTTCCAGCCCACCTACCCCTATGTGCAGCACGAGATTGAT
CTTCCTCCCACCATCTCCCTGTCCGACGGTGAAGAGCCACCTCCTTACCAGGGGCCCTGCACCCTGCAGCTCCGGGACCCTGAACAGCAG
ATGGAACTCAACCGAGAGTCCGTGAGGGCCCCACCCAACCGAACCATATTTGACAGTGATTTAATAGACATTGCTATGTATAGCGGGGGT
CCATGCCCACCCAGCAGCAACTCGGGCATCAGTGCAAGCACCTGCAGCAGTAACGGGAGGATGGAGGGGCCACCCCCCACATACAGCGAG
GTGATGGGCCACCACCCAGGCGCCTCTTTCCTCCATCACCAGCGCAGCAACGCACACAGGGGCAGCAGACTGCAGTTTCAGCAGAACAAT
GCAGAGAGCACAATAGTACCCATCAAAGGCAAAGATAGGAAGCCTGGGAACCTGGTCTGATTCCTTCCAACGTGCACTTCAGCTGGAGAA
AGAAACCAAGAAGGGAAGCGGCCGCTGGGCCCCTCCTGCGCACAGTGTTGTTCAGTTTCACATGGTACAAATAAGTAAAACCAAATGAGC
AAACACGGTCTTTGTTTCTGATTCCTTTTAGGGGAATTGCATGCAAACTAGACTGAAATGATACAAACTTCCATCTGGTCTGACCGCAAA
CAGTGTTTATTTGGGGACAGGGGTTGGGATGGGGGTGTGGGCAGGGGAAAACAGAGAACGGGATGCTTTGAAGATACCATGAAATAAAAC
CCACAGAGGTATTTGATGTATTTAATTGTGAAAGGAGACTTTGCAGATAAATGAGGCCAGAATGGCATGTTTTATAATTAACTGAATAAA
GAAGGAAGCATTATTATATATTATTGTGGGGAAGAACCAGCCAGTTCGCTTTTTCTCCTAAGGTGTGGAACTTTTATTTTGTTTTAAAAA
TATGAATCAAAATTCCTGTGTTGTGTGCCAAGGTATAAAGTGGAGAAGTTAGATGAGTGCAAGGAGCTCCTTTGTGTTGTGATGATGTGT
TTTAAAAGTTGCACTATCTTAATGTTGAAAATATTTACAAGGGAACTGTTTTACGTGAAGTTCTGTATGTTGTCTTTTCACCTGTGGATT
GTAATCAGGCCCAAGGAATATCCTGGAGTGGTCCCCAGAAGCATCCAAGAAAAGATATTTGGGGACGTAGCCTAACATTTTACCAACTTA
CGTAAATCAAAAAAGTCATTATTGTTGCAGGAGTTTGCATCAAATAGCAGTGCATCGCTGAAGCTTTTGGAGACTTTTGGATGGAAGATA
AGATAGGGAAGATTAAGTTCCAGCATTTCTGACTTGTTATTTTGAGTTACTCTGCTACTCTTAGGCTGCATAGTTTATGAGAAAATGAAC
ACATGCATTTATGGATCCAGTATCATGCAGTGCTGCCCTCATCCTCCAGCAGTGCAATTTCTTCAGTAATTTAGATTTTTTTCACTATAG
CATGAAATATATTCAAATACATACCTTATTTTATGCAATAAATTGTTTAAAATGCAAGGTGGTTATTCTGCATACTGTTGAAATATGTGA
CTCCTCAGTATATTCCCATTGCCTCTCCCCCTTTCCTCGACAGCTTAGTTCAGTTCTGCAGGGCTGCTCAGTTCACAGGAGGCTCCCAGC
AGCCACCCCACATCCAGCCTACACAGAACTTCGTGTGGGAGTGGTGTGGGTGGTGGTTTCTTATGCTTTGGAAGCCCCTAGAAATAATGA
CGGAAGAATGCCATGTTGCTGATCGTGGTAATAAGCCATTGTGGGTTATTGTATGTCACTAGTATTAGCATAGCATTCTTAAAGGAATGC
AGTGCTCAAAACCTACCCAAATTCCCGCAGGATTCTACCAAACCCTTCCCCAGGCCAGCTTTTGTACTGAAGGCAAGAACTGGACAGTCA
GAGAACAGTGGAGGGGGCAAGTGACTGAAGAGCACCGGGTAAAAAGCACAACATGCAGTTAAAATGCAACTAGAAAACTAATTTTAAATA
TTGTTAGTTTTAATATTCCTGATATTTACAAATATTCATTCTTATATACAATGAAAAAAATAACTTTCTTCTGCAGATGTAAGCACTGGC
TTTTATAAGAGCAGCAGCCAACACGTTTAGCAGACACTGCGCGTGGAGAAGGGCTTATCTGCAGTACACTCTGCCATGTGGAGGGTGGGC
CTCTGTGGCCTCTTCACATAACAAGATGAGCTGGAATGATGATTCCATGACTCCCACCTATGCAGCCTTAAAGCCAAATCCGCGTGTGTG
TGTTTGTGTCTGTCTGTGGGTCTCGAAGGTGATCCGTCGGTGCGGTGGCTCTGTGCTGTAACTGGAGAGACTGTTCCAAACCCCAAGAGT
TGTCTGATCCTAGTCTGTTCCCTTCTGCTTCTTACCTCTGTAGATAGGTCACTGGTTTTTGTTTGTTTGTTTTGAGGATTGGAATTTCCA
TTACATTCATCCTTTGCACACAGTAACATCCACAGAACTAGTCCAACTCTTAAAAGGAGAGAGGAAAAACACAGGCACCAGTTGTCAGCT
CATGCTTACAACCTGTGTGGAAGTATATACAGTTGAGAGTCACAGTGGAGGTTCTGAGACTGGATTCAGTCTTGTTCCAGTGACAGTTGG
AAGGCCTCTGCTGGAGAGACACCAGCTCTCAGGGCAGAGATTGGCTTGGGGCCAGAAGGACCCTCCCCAACCCTGGAGACACCCTGAAGG
TTCACTGGCTCTCCAGATTAGCCTCTCTTCCTCTGTCAGGCAAAGATGAGGAGCCCGTGTTCCCATCGGGCCCTGCTGGCAGGGACTTGC
AGTGGATTCTTGGTCAGGTGTGCCCACAGATGCGGAGGCGAGGTGAGTGATTCCATCATTTCAGTTCTCACCTGCAGTTTTGGTGAAGCA
GGAGATGCACCCCACAGCTCTAGCTCTCAAATGGCTTCACAGTCCTTACTTCTCTACCTGCCTCAAGAAGGGGCTCAGAGCAGAGACTTG
TGAATTCCTTAGTAACTGTGAGTATATGAATGTGTTGCACATGTCCACAGTATTGGCGAGATAATTACATAATTCAGATACCTTTAATCA
TCTTTCAAGAAAGAGGCTCCTCCCATTCAACCACCCTAGAGAACTGCCTTTGTTAAATAGTTATTTAAAGACTCATACATATCAAACCAT
GACTTTGAAAGGTCTTCGAGGCTGGGGCTCTGTAATGAATTAGTTTAAAAGCCAAGGTCATAACATGAATTGATGGTCAATTTCCCTTCA
GCAGAAGGAAAAGGTGATTTAGATCAGTAGCTCTTTTGAAGGTTGTGGCTGACCTGTTCATACCGTGTCGCCTCATGGCTAGTGTGGCGT
TGAAAGAGTAGCGACTGGGAAGATACAACTTACACAGTGGGGCCTATTGTTCTTTCAAGAACCCTTTTTTTAGCTTATAGAACCCATGGG
TCCAGTTTAGTAACGAGTGATTTAGGCAATCAATGATAGGTTTATAATCTTAGATTATTCCAGCAAAGTGTGGATTGCATTGTTAGGAAG
AACATTTGGTGGGAATGAACACTCCTGGGCATACCGCTGACTTTTGTCCCTTGTTCCCGGTGTAGGAGACCCAAGGCATCTTGAATCCCA
TCTATAAGAACACAATCTTCCAGCATACGTTTGCTTTTTCAGAAACTCTAGCATTCTCTTTAAATACTGACGCAATCCTTAATGGAAAAG
AGATTTCATGAAGCAAATTATGTATTTCAATAGTTCTTCTATTTTTAGTGTCCAAAATTTACTAATACAGAAGCTTGACAAGCATGTCCT
CACCCTCCCCACCACATAAACACATGGACACACACCCAAGCCACAAGAAATCCCAAGAGAGCAGAAGCGAATTTTTAAAAGATTTATCGT
GAGGACTGCATTTCCATTCACTAATTTTGGCTCAAACTTATGAGGCAGGAAATAGGGGCCAACAGTAAATGGGGGAGGCCTCCTGACACC
AGCAGAGGAATTTTGTACCCAGGCGAGGACTTCTTGAACTTCTGCGTATCTCCGTTTGATCTCTTTCACCTTTATTTCATCTTCATAAGA
ATGAGAAAGGCTCAAAAGGAAGCACTTTTAGAAATCTTCTCTGACCTAGAAGAATCCATCCAAATCCCTGCCTTCCTCTCTGAACCAACA
GTTCCCTTCTCTGACAGGGGCCATCCTCTATCTTCCATCCAGCGGCTCTTCTTTTTAGGAAGGCTCTGGTGCAGAGCACTTCAAATATGT
CCTCAGGCCAGATACTGATTGCTAGTAGAGAGACACCCGGCACCCAGTCCGAAGCCCTCCCTCAAAGGACCGGCTCATGGCGTTGGTCAC
TGGCAGGCTCAGAGACATTCTGCTGTGGGCGCAGGGAGCCCGGCCCCCCATGCAGCCATGACTGGATGCGCCCCCATCTCGGGGGCTTGC
TGCACTGCTTGTTTATTGAATTTTGCTACTTAGAATGGCAACATTAACTTTGTGTACCATTCATTTTTTAAAAATTTTCCAAAGCTCGGC
AGTGTATGAAAGAAAAAACTGGGAAAGATACTTGGTTTCTGTTAACTTTTGTGTTGCTTGCTTAAGTGATTAAAGCCAGTGCTTGGAGCC
AAGCCTTCATGCCACGAACATGCTCCACAGCCTGCCCTTTGCTCTCCTGCTCACACTGACCAAGAATGCCGCGTGCTTGGCCTACTGAGG
TGAAAGGACAATTGAATGACAGGTGGGCAAAGGGAGAACTTCCCCTTCTTGGTGCGAGGAAAGTCACAAATTTAAAAATGTTGCTTCCAG
CCCAGATCCTAAATGCTAGTTCTCAGCAGCTGCGTGGCTTACCGTTCGCCATTTCCACCACCGCCAGCTGCCAGCACCGCTACAGATCAC
AGAGATGTGAACAGACAATGGAAAGCACTCTTAGCCTTGCAGTGGTCTACATTTTTTAGGAACCAATATTTCAGCATTCTTTATTACCCG
GCACGCTGTGTCCTTTGCAGAGTTCAAGTTTATGTTACTGCCAGGGTCAGACAGTCATTTGCTGCTGCTGCTGCTGCTGCTGCTTCTCGA
ACTGGATGCATTAGGAAGCTGCTGTCTGAGTGTAGGAATGTCTTGCTAAGAAAGCAATGTCTTCCTTCATCCTTTTCTTTCTTCCCTCTG
CGTGTCCTTGTTTTTGTGTAATGCGGGAGAGGGTTAGAGCTATAGAGATTATATATACACTATCCGTGCACATTATATATATGTAGATAT
ACCCCTATCATGTCAGAGATCTGCATGTCAGTTTTTCAGCAACTAAGGTGCCTCATGTTCTGAGTTCAGCAGATATAGGAACCAAGCCGC
CCCCTCCTGCACTTGATGCTCCCACCTTTGTTGTGCCTCACTTAAAATGGTGCTTTTTTCAGTTGTCTGTCTTTTCTTATGTTTTTATTT
GTAAGGTGCTGTATATAAGTTGAATATATTATGCACATATCCTACCCAATGGGTAGAACAAAAAGTTGTTAATACTGTAATATAATGTAT
AGATGATACCAATTTTAACAGAAATGGCATAGAATTTGTGAATGCCTATGTGCTTTGTCCTCTTTTGTAAGGAAATTTGCAAATGGATGC
ATACAGATTAAAGTCTATGTAGTTTATTTTCCTATTAAATATCAATATTATAACACAAGAGAAAGAAGTGTGAACAAACAAGCAACAGTT
TATGACCAGCGTATATATAGCAATGGAAAGTTGCATCTTTGCTGTGAAAACACTTTAAAGAAAATACTTTTTAAAAAATCCCACAGCTTT
TTGGTTGCCACTAGACGCTTCTTATTTTAATCATTTTAGTAATGCTCAGCTGGACCAGTGTTAGTTATATTTGAGTCAGAAAAATGTTGT
TTTTCAACTTGCTTTATAATCTCCTGCATCTATCTCCTGCTGTAGCATCACGAAGGTGTCAGGCAACAGTGAAAAGTGCACATTTTTGTT
GTTGCAGAAACTGTGTCAGAGGAATAAGTAAATCAGCCTGCAGCAGAAGACTTTGTTCAGCTCCAGAGGCATCTGTGACCGTCTGTGTCC
AAGTCTCTCTGTGCCTTTTTCTTTTACAAACTGAAGCTGTGGAGCCAATGAAGTAACAGTAGAGATTGTAGGGAAAGAATACCTCAGGAA
AAACAAATACACTTACAAGAAGACCCTGTTCTTAGAAAATGTGTTTAGTTATGGGTTAGCACTAGAAGAGACTTGGCTGTCAGCCAGCCA
AGTGAAGGACCTCTCATCCATTCCCATTCATGTCCCATCATAATACGGACCCAAAAAGCAAACTCGGTTTTGCCATCAGTTAGAAATTAC
GTTTTGGATTGTATATTGTTACATCTCTCTTCCGGCTTAGTTTTTAGTGTCTGATTGTGACCTCTGCATTTATCTTCAAATACCCTAATT
TTAAAACAAAAGAACAAGAAAAGTTTATAACACCATGTTCACTAAAACCACGGTTGAATCTTGGGTGTGGGCATCCTTTCGAGTGTTGTC
CATAAGAGCAGTTCGTGGAATTTTGCCCATCTGACCCATATTATCAGCTTATTCTGCCACCAGAGTAGAGTCTAATAAATTCCAAAGTTT
TTATTTGCTCCATGGTGTATGTTCTGACTTTGAAAATGTCAGATTCTATAATCATACCCCTAACATCCAGGAAACAAATGACAGATTATC
TTTAAACTGAAATTGACTCTACAATGCAACCCTTAATGCTGAATGGATTAAAAAAGTCAGCCCTTTTAGTATCTGTTTGAAAGGGCCGTA
AAAAGTTGACACTTTTGTTGTTGTGGATCCTGCGTGTCTAGACCCACGTGTTGTTTCCATCGTATACTGTAGGGTGCACCCCTTGGGATT
CATCATTAAGAACTGAGGCTCACTGTTGTCAGAAACAAAGCTCCCACCCCCCAGGTTCAACCTTGTGGGAGAACTGTTGAGCATGAGAAT
GTTCTAGACTCAGAGGTACTAAAATTTGTTACCACATCATTGCTTCCTTTCTACAGGACGAATTGAGGCTTAAACTTTACTGTTAATGAT
ACTGGTTCATTTTAATGTGCTTGTTGGTATGTTGCTATTTTTCATTTCATAGCTTTCAAAAATCATGCTAATTGTATACTTGTCTAGTTT
AAGGCTATTTTAAAATATGTACAATACTATTCACAGCATTTAGTTCGTTTAATTTTTATTATAAAGCAATCTACTAAAAAAGTACAACTG
TATTTGAACTTTTCAATAGTTGTTTGTGAGCTATGATAATCAAAAGTCATTAAAGTCTTTTTTAACAAACATTCGTGCTTACTTTTCAAC
ATAATTCCCAGTTATATACAGAAAAAGATTTCCACCTGTCACGTATCTGCCTCTTTTACCTGAGCAATGGTGTAGTTCTTAGACCTAAGG
TCTGTAATTGCAATACTTTTAAAGAAAGATGTTGCTCTAAGTGCTGTTTGTTAGTTATGAAATCAGATTTTTCTGCTTGTTCTTAATGCT

>59639_59639_3_NOP56-LDLRAD4_NOP56_chr20_2634039_ENST00000329276_LDLRAD4_chr18_13621116_ENST00000399848_length(amino acids)=297AA_BP=69
MVLLHVLFEHAVGYALLALKEVEEISLLQPQVEESVLNLGKFHSIVRLVAFCPFASSQVALENANAVSEAELEFAQIIIIVVVVTVMVVV
IVCLLNHYKVSTRSFINRPNQSRRREDGLPQIMHAPRSRDRFTAPSFIQRDRFSRFQPTYPYVQHEIDLPPTISLSDGEEPPPYQGPCTL
QLRDPEQQMELNRESVRAPPNRTIFDSDLIDIAMYSGGPCPPSSNSGISASTCSSNGRMEGPPPTYSEVMGHHPGASFLHHQRSNAHRGS

--------------------------------------------------------------
>59639_59639_4_NOP56-LDLRAD4_NOP56_chr20_2634039_ENST00000329276_LDLRAD4_chr18_13621116_ENST00000587757_length(transcript)=1584nt_BP=724nt
GGCTCGTCCCCGAGTAGGGGACGGGAACGCCTGGGTCCCGGGGACGTGGGGCGCAGGGTCTGGGGCCCGAGGCCACGGACGAAGCGGGAA
GCCGGCTAGGCAGCGGTCTCTGTCTGGGATGGACGCCGCGCCCCACGCGGACCTCCCGCCCCGACTTCACCCAGCTCTGCTGCCCGTAAC
TCATATGACAAGAACATCAGGAACCGGACTATTACCCCGAAAGGGCCTTCCCAAGTCGTTTCGCCGCCTGCAGTGCCCGACCGGGGGCCG
CGCGTCCCCGGCAACCACGCCCGCCCGCGCAGCTGCAGAGGCCGGAAAAGGCCCGCTCGCCCGCGCTCGGCACCACCCAGCCCGCGCTCC
GGGCGATACCACCCTGGGCGGCCCCTCCAAAGGCCGGAGATGGTGTCGTCCCCGGCCTCCGATTGGTCGGGGGGGCGGGGGCGTGGCCTC
TGGAGCCTGGTTCCGCGCGCCGGAGCGCGCTAGCCGCATTGCGAGCCGAACCCGGGAGCTGGCGCCATGGTGCTGTTGCACGTGCTGTTT
GAGCACGCGGTCGGCTACGCGCTGCTGGCGCTGAAGGAAGTGGAGGAGATCAGTCTGCTGCAGCCGCAGGTGGAGGAGTCTGTGCTCAAC
CTGGGCAAATTCCACAGCATCGTTCGTCTGGTGGCCTTTTGTCCCTTTGCCTCATCCCAGGTTGCCTTGGAAAATGCCAACGCCGTGTCT
GAAGCGGAGCTGGAGTTCGCCCAAATCATCATCATCGTCGTGGTGGTCACGGTGATGGTGGTGGTCATCGTCTGCCTGCTGAACCACTAC
AAAGTCTCCACGCGGTCCTTCATCAACCGCCCGAACCAGAGCCGGAGGCGGGAGGACGGGCTGCCGCAGGAAGGGTGCCTGTGGCCTTCA
GACAGCGCCGCACCGCGGCTGGGCGCCTCGGAGATCATGCATGCCCCGCGGTCCAGGGACAGGTTCACAGCGCCGTCCTTCATCCAGAGG
GATCGCTTCAGCCGCTTCCAGCCCACCTACCCCTATGTGCAGCACGAGATTGATCTTCCTCCCACCATCTCCCTGTCCGACGGTGAAGAG
CCACCTCCTTACCAGGGGCCCTGCACCCTGCAGCTCCGGGACCCTGAACAGCAGATGGAACTCAACCGAGAGTCCGTGAGGGCCCCACCC
AACCGAACCATATTTGACAGTGATTTAATAGACATTGCTATGTATAGCGGGGGTCCATGCCCACCCAGCAGCAACTCGGGCATCAGTGCA
AGCACCTGCAGCAGTAACGGGAGGATGGAGGGGCCACCCCCCACATACAGCGAGGTGATGGGCCACCACCCAGGCGCCTCTTTCCTCCAT
CACCAGCGCAGCAACGCACACAGGGGCAGCAGACTGCAGTTTCAGCAGAACAATGCAGAGAGCACAATAGTACCCATCAAAGGCAAAGAT
AGGAAGCCTGGGAACCTGGTCTGATTCCTTCCAACGTGCACTTCAGCTGGAGAAAGAAACCAAGAAGGGAAGCGGCCGCTGGGCCCCTCC

>59639_59639_4_NOP56-LDLRAD4_NOP56_chr20_2634039_ENST00000329276_LDLRAD4_chr18_13621116_ENST00000587757_length(amino acids)=315AA_BP=69
MVLLHVLFEHAVGYALLALKEVEEISLLQPQVEESVLNLGKFHSIVRLVAFCPFASSQVALENANAVSEAELEFAQIIIIVVVVTVMVVV
IVCLLNHYKVSTRSFINRPNQSRRREDGLPQEGCLWPSDSAAPRLGASEIMHAPRSRDRFTAPSFIQRDRFSRFQPTYPYVQHEIDLPPT
ISLSDGEEPPPYQGPCTLQLRDPEQQMELNRESVRAPPNRTIFDSDLIDIAMYSGGPCPPSSNSGISASTCSSNGRMEGPPPTYSEVMGH

--------------------------------------------------------------

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Fusion Gene PPI Analysis for NOP56-LDLRAD4


check button Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in

ChiPPI page.


check button Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160)
HgeneHgene's interactorsTgeneTgene's interactors


check button - Retained PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenStill interaction with


check button - Lost PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


check button - Retained PPIs, but lost function due to frame-shift fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


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Related Drugs for NOP56-LDLRAD4


check button Drugs targeting genes involved in this fusion gene.
(DrugBank Version 5.1.8 2021-05-08)
PartnerGeneUniProtAccDrugBank IDDrug nameDrug activityDrug typeDrug status

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Related Diseases for NOP56-LDLRAD4


check button Diseases associated with fusion partners.
(DisGeNet 4.0)
PartnerGeneDisease IDDisease name# pubmedsSource