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Center for Computational Systems Medicine
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Fusion Gene Summary

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Fusion Gene ORF analysis

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Fusion Genomic Features

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Fusion Protein Features

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Fusion Gene Sequence

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Fusion Gene PPI analysis

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Related Drugs

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Related Diseases

Fusion gene:NOVA1-CHMP1A (FusionGDB2 ID:59795)

Fusion Gene Summary for NOVA1-CHMP1A

check button Fusion gene summary
Fusion gene informationFusion gene name: NOVA1-CHMP1A
Fusion gene ID: 59795
HgeneTgene
Gene symbol

NOVA1

CHMP1A

Gene ID

4857

5119

Gene nameNOVA alternative splicing regulator 1charged multivesicular body protein 1A
SynonymsNova-1CHMP1|PCH8|PCOLN3|PRSM1|VPS46-1|VPS46A
Cytomap

14q12

16q24.3

Type of geneprotein-codingprotein-coding
DescriptionRNA-binding protein Nova-1neuro-oncological ventral antigen 1onconeural ventral antigen 1paraneoplastic Ri antigenventral neuron-specific protein 1charged multivesicular body protein 1acharged multivesicular body protein 1/chromatin modifying protein 1chromatin modifying protein 1Aprocollagen (type III) N-endopeptidaseprotease, metallo, 1, 33kDvacuolar protein sorting-associated protein 46-1
Modification date2020032720200313
UniProtAcc.

Q9HD42

Ensembl transtripts involved in fusion geneENST00000267422, ENST00000344429, 
ENST00000539517, ENST00000465357, 
ENST00000547619, ENST00000551754, 
ENST00000574031, 		ENST00000547614, 
ENST00000253475, ENST00000397901, 
ENST00000535997, ENST00000550102, 
Fusion gene scores* DoF score7 X 5 X 5=17545 X 11 X 21=10395
# samples 848
** MAII scorelog2(8/175*10)=-1.12928301694497
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0		log2(48/10395*10)=-4.43671154213721
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0
Context

PubMed: NOVA1 [Title/Abstract] AND CHMP1A [Title/Abstract] AND fusion [Title/Abstract]

Most frequent breakpointNOVA1(26941526)-CHMP1A(89713739), # samples:3
Anticipated loss of major functional domain due to fusion event.NOVA1-CHMP1A seems lost the major protein functional domain in Hgene partner, which is a essential gene due to the frame-shifted ORF.
* DoF score (Degree of Frequency) = # partners X # break points X # cancer types
** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)

check button Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez
PartnerGeneGO IDGO termPubMed ID
TgeneCHMP1A

GO:0007076

mitotic chromosome condensation

11559747

TgeneCHMP1A

GO:0016192

vesicle-mediated transport

11559748

TgeneCHMP1A

GO:0016458

gene silencing

11559747

TgeneCHMP1A

GO:0045892

negative regulation of transcription, DNA-templated

11559747


check buttonFusion gene breakpoints across NOVA1 (5'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check buttonFusion gene breakpoints across CHMP1A (3'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check button Fusion gene information from two resources (ChiTars 5.0 and ChimerDB 4.0)
* All genome coordinats were lifted-over on hg19.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
SourceDiseaseSampleHgeneHchrHbpHstrandTgeneTchrTbpTstrand
ChimerDB4GBMTCGA-02-2483-01ANOVA1chr14

26941526

-CHMP1Achr16

89713739

-
ChimerDB4GBMTCGA-06-0210-02ANOVA1chr14

26941526

-CHMP1Achr16

89713739

-
ChimerDB4GBMTCGA-12-0618-01ANOVA1chr14

26941526

-CHMP1Achr16

89713739

-


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Fusion Gene ORF analysis for NOVA1-CHMP1A

check button Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
ORFHenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrand
5CDS-5UTRENST00000267422ENST00000547614NOVA1chr14

26941526

-CHMP1Achr16

89713739

-
5CDS-5UTRENST00000344429ENST00000547614NOVA1chr14

26941526

-CHMP1Achr16

89713739

-
5CDS-5UTRENST00000539517ENST00000547614NOVA1chr14

26941526

-CHMP1Achr16

89713739

-
Frame-shiftENST00000267422ENST00000253475NOVA1chr14

26941526

-CHMP1Achr16

89713739

-
Frame-shiftENST00000267422ENST00000397901NOVA1chr14

26941526

-CHMP1Achr16

89713739

-
Frame-shiftENST00000267422ENST00000535997NOVA1chr14

26941526

-CHMP1Achr16

89713739

-
Frame-shiftENST00000267422ENST00000550102NOVA1chr14

26941526

-CHMP1Achr16

89713739

-
Frame-shiftENST00000344429ENST00000253475NOVA1chr14

26941526

-CHMP1Achr16

89713739

-
Frame-shiftENST00000539517ENST00000253475NOVA1chr14

26941526

-CHMP1Achr16

89713739

-
In-frameENST00000344429ENST00000397901NOVA1chr14

26941526

-CHMP1Achr16

89713739

-
In-frameENST00000344429ENST00000535997NOVA1chr14

26941526

-CHMP1Achr16

89713739

-
In-frameENST00000344429ENST00000550102NOVA1chr14

26941526

-CHMP1Achr16

89713739

-
In-frameENST00000539517ENST00000397901NOVA1chr14

26941526

-CHMP1Achr16

89713739

-
In-frameENST00000539517ENST00000535997NOVA1chr14

26941526

-CHMP1Achr16

89713739

-
In-frameENST00000539517ENST00000550102NOVA1chr14

26941526

-CHMP1Achr16

89713739

-
intron-3CDSENST00000465357ENST00000253475NOVA1chr14

26941526

-CHMP1Achr16

89713739

-
intron-3CDSENST00000465357ENST00000397901NOVA1chr14

26941526

-CHMP1Achr16

89713739

-
intron-3CDSENST00000465357ENST00000535997NOVA1chr14

26941526

-CHMP1Achr16

89713739

-
intron-3CDSENST00000465357ENST00000550102NOVA1chr14

26941526

-CHMP1Achr16

89713739

-
intron-3CDSENST00000547619ENST00000253475NOVA1chr14

26941526

-CHMP1Achr16

89713739

-
intron-3CDSENST00000547619ENST00000397901NOVA1chr14

26941526

-CHMP1Achr16

89713739

-
intron-3CDSENST00000547619ENST00000535997NOVA1chr14

26941526

-CHMP1Achr16

89713739

-
intron-3CDSENST00000547619ENST00000550102NOVA1chr14

26941526

-CHMP1Achr16

89713739

-
intron-3CDSENST00000551754ENST00000253475NOVA1chr14

26941526

-CHMP1Achr16

89713739

-
intron-3CDSENST00000551754ENST00000397901NOVA1chr14

26941526

-CHMP1Achr16

89713739

-
intron-3CDSENST00000551754ENST00000535997NOVA1chr14

26941526

-CHMP1Achr16

89713739

-
intron-3CDSENST00000551754ENST00000550102NOVA1chr14

26941526

-CHMP1Achr16

89713739

-
intron-3CDSENST00000574031ENST00000253475NOVA1chr14

26941526

-CHMP1Achr16

89713739

-
intron-3CDSENST00000574031ENST00000397901NOVA1chr14

26941526

-CHMP1Achr16

89713739

-
intron-3CDSENST00000574031ENST00000535997NOVA1chr14

26941526

-CHMP1Achr16

89713739

-
intron-3CDSENST00000574031ENST00000550102NOVA1chr14

26941526

-CHMP1Achr16

89713739

-
intron-5UTRENST00000465357ENST00000547614NOVA1chr14

26941526

-CHMP1Achr16

89713739

-
intron-5UTRENST00000547619ENST00000547614NOVA1chr14

26941526

-CHMP1Achr16

89713739

-
intron-5UTRENST00000551754ENST00000547614NOVA1chr14

26941526

-CHMP1Achr16

89713739

-
intron-5UTRENST00000574031ENST00000547614NOVA1chr14

26941526

-CHMP1Achr16

89713739

-

check buttonORFfinder result based on the fusion transcript sequence of in-frame fusion genes.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandSeq length
(transcript)		BP loci
(transcript)		Predicted start
(transcript)		Predicted stop
(transcript)		Seq length
(amino acids)
ENST00000539517NOVA1chr1426941526-ENST00000397901CHMP1Achr1689713739-28118373181175285
ENST00000539517NOVA1chr1426941526-ENST00000535997CHMP1Achr1689713739-27798373181175285
ENST00000539517NOVA1chr1426941526-ENST00000550102CHMP1Achr1689713739-13538373181175285
ENST00000344429NOVA1chr1426941526-ENST00000397901CHMP1Achr1689713739-24975234861285
ENST00000344429NOVA1chr1426941526-ENST00000535997CHMP1Achr1689713739-24655234861285
ENST00000344429NOVA1chr1426941526-ENST00000550102CHMP1Achr1689713739-10395234861285

check buttonDeepORF prediction of the coding potential based on the fusion transcript sequence of in-frame fusion genes. DeepORF is a coding potential classifier based on convolutional neural network by comparing the real Ribo-seq data. If the no-coding score < 0.5 and coding score > 0.5, then the in-frame fusion transcript is predicted as being likely translated.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandNo-coding scoreCoding score
ENST00000539517ENST00000397901NOVA1chr1426941526-CHMP1Achr1689713739-0.0056449240.9943551
ENST00000539517ENST00000535997NOVA1chr1426941526-CHMP1Achr1689713739-0.0058581470.9941419
ENST00000539517ENST00000550102NOVA1chr1426941526-CHMP1Achr1689713739-0.0063040280.99369603
ENST00000344429ENST00000397901NOVA1chr1426941526-CHMP1Achr1689713739-0.0058494560.99415046
ENST00000344429ENST00000535997NOVA1chr1426941526-CHMP1Achr1689713739-0.0059552340.99404484
ENST00000344429ENST00000550102NOVA1chr1426941526-CHMP1Achr1689713739-0.0032562350.9967437

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Fusion Genomic Features for NOVA1-CHMP1A


check buttonFusionAI prediction of the potential fusion gene breakpoint based on the pre-mature RNA sequence context (+/- 5kb of individual partner genes, total 20kb length sequence). FusionAI is a fusion gene breakpoint classifier based on convolutional neural network by comparing the fusion positive and negative sequence context of ~ 20K fusion gene data. From here, we can have the relative potentency of the 20K genomic sequence how individual sequnce will be likely used as the gene fusion breakpoints.
HgeneHchrHbpHstrandTgeneTchrTbpTstrand1-pp (fusion gene breakpoint)

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions. We integrated a total of 44 different types of human genomic feature loci information across five big categories including virus integration sites, repeats, structural variants, chromatin states, and gene expression regulation. More details are in help page.
genomic feature

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions that are ovelapped with the top 1% feature importance score regions. More details are in help page.

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Fusion Protein Features for NOVA1-CHMP1A


check button Four levels of functional features of fusion genes
Go to FGviewer search page for the most frequent breakpoint (https://ccsmweb.uth.edu/FGviewer/chr14:26941526/chr16:89713739)
- FGviewer provides the online visualization of the retention search of the protein functional features across DNA, RNA, protein, and pathological levels.
- How to search
1. Put your fusion gene symbol.
2. Press the tab key until there will be shown the breakpoint information filled.
4. Go down and press 'Search' tab twice.
4. Go down to have the hyperlink of the search result.
5. Click the hyperlink.
6. See the FGviewer result for your fusion gene.
FGviewer

check buttonMain function of each fusion partner protein. (from UniProt)
HgeneTgene
.CHMP1A

Q9HD42

FUNCTION: Transcriptional activator which is required for calcium-dependent dendritic growth and branching in cortical neurons. Recruits CREB-binding protein (CREBBP) to nuclear bodies. Component of the CREST-BRG1 complex, a multiprotein complex that regulates promoter activation by orchestrating a calcium-dependent release of a repressor complex and a recruitment of an activator complex. In resting neurons, transcription of the c-FOS promoter is inhibited by BRG1-dependent recruitment of a phospho-RB1-HDAC1 repressor complex. Upon calcium influx, RB1 is dephosphorylated by calcineurin, which leads to release of the repressor complex. At the same time, there is increased recruitment of CREBBP to the promoter by a CREST-dependent mechanism, which leads to transcriptional activation. The CREST-BRG1 complex also binds to the NR2B promoter, and activity-dependent induction of NR2B expression involves a release of HDAC1 and recruitment of CREBBP (By similarity). {ECO:0000250}.FUNCTION: Probable peripherally associated component of the endosomal sorting required for transport complex III (ESCRT-III) which is involved in multivesicular bodies (MVBs) formation and sorting of endosomal cargo proteins into MVBs. MVBs contain intraluminal vesicles (ILVs) that are generated by invagination and scission from the limiting membrane of the endosome and mostly are delivered to lysosomes enabling degradation of membrane proteins, such as stimulated growth factor receptors, lysosomal enzymes and lipids. The MVB pathway appears to require the sequential function of ESCRT-O, -I,-II and -III complexes. ESCRT-III proteins mostly dissociate from the invaginating membrane before the ILV is released. The ESCRT machinery also functions in topologically equivalent membrane fission events, such as the terminal stages of cytokinesis and the budding of enveloped viruses (HIV-1 and other lentiviruses). ESCRT-III proteins are believed to mediate the necessary vesicle extrusion and/or membrane fission activities, possibly in conjunction with the AAA ATPase VPS4. Involved in cytokinesis. Involved in recruiting VPS4A and/or VPS4B to the midbody of dividing cells. May also be involved in chromosome condensation. Targets the Polycomb group (PcG) protein BMI1/PCGF4 to regions of condensed chromatin. May play a role in stable cell cycle progression and in PcG gene silencing. {ECO:0000269|PubMed:11559747, ECO:0000269|PubMed:11559748, ECO:0000269|PubMed:19129479, ECO:0000269|PubMed:23045692}.

check buttonRetention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at

download page


* Minus value of BPloci means that the break pointn is located before the CDS.
- In-frame and retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneNOVA1chr14:26941526chr16:89713739ENST00000344429-4549_116173182.0DomainKH 1
HgeneNOVA1chr14:26941526chr16:89713739ENST00000539517-4549_116173508.0DomainKH 1
HgeneNOVA1chr14:26941526chr16:89713739ENST00000344429-4527_43173182.0MotifBipartite nuclear localization signal
HgeneNOVA1chr14:26941526chr16:89713739ENST00000539517-4527_43173508.0MotifBipartite nuclear localization signal
TgeneCHMP1Achr14:26941526chr16:89713739ENST0000039790137102_12484197.0Coiled coilOntology_term=ECO:0000255
TgeneCHMP1Achr14:26941526chr16:89713739ENST0000039790137185_19584197.0MotifNote=MIT-interacting motif

- In-frame and not-retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneNOVA1chr14:26941526chr16:89713739ENST00000344429-45273_409173182.0Compositional biasNote=Ala-rich
HgeneNOVA1chr14:26941526chr16:89713739ENST00000465357-14273_4090484.0Compositional biasNote=Ala-rich
HgeneNOVA1chr14:26941526chr16:89713739ENST00000539517-45273_409173508.0Compositional biasNote=Ala-rich
HgeneNOVA1chr14:26941526chr16:89713739ENST00000344429-45171_237173182.0DomainKH 2
HgeneNOVA1chr14:26941526chr16:89713739ENST00000344429-45421_488173182.0DomainKH 3
HgeneNOVA1chr14:26941526chr16:89713739ENST00000465357-14171_2370484.0DomainKH 2
HgeneNOVA1chr14:26941526chr16:89713739ENST00000465357-14421_4880484.0DomainKH 3
HgeneNOVA1chr14:26941526chr16:89713739ENST00000465357-1449_1160484.0DomainKH 1
HgeneNOVA1chr14:26941526chr16:89713739ENST00000539517-45171_237173508.0DomainKH 2
HgeneNOVA1chr14:26941526chr16:89713739ENST00000539517-45421_488173508.0DomainKH 3
HgeneNOVA1chr14:26941526chr16:89713739ENST00000465357-1427_430484.0MotifBipartite nuclear localization signal
TgeneCHMP1Achr14:26941526chr16:89713739ENST00000397901375_4784197.0Coiled coilOntology_term=ECO:0000255


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Fusion Gene Sequence for NOVA1-CHMP1A


check button For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. To have fusion amino acid sequence, we ran ORFfinder and chose the longest ORF among the all predicted ones.
>59795_59795_1_NOVA1-CHMP1A_NOVA1_chr14_26941526_ENST00000344429_CHMP1A_chr16_89713739_ENST00000397901_length(transcript)=2497nt_BP=523nt
AAACATGATGGCGGCAGCTCCCATCCAGCAGAACGGGACCCACACTGGGGTTCCCATAGACCTGGACCCGCCGGACTCGCGGAAAAGGCC
GCTGGAAGCCCCCCCTGAAGCCGGCAGCACCAAGAGGACCAATACGGGCGAAGACGGCCAGTATTTTCTAAAGGTTCTCATACCTAGTTA
TGCTGCTGGATCTATAATTGGGAAGGGAGGACAGACAATTGTTCAGTTGCAAAAAGAAACTGGAGCCACCATCAAGCTGTCTAAGTCCAA
AGATTTTTACCCAGGTACTACTGAGCGAGTGTGCTTGATCCAGGGAACGGTTGAAGCACTGAATGCAGTTCATGGATTCATTGCAGAAAA
AATTCGAGAAATGCCCCAAAATGTGGCCAAGACAGAACCAGTCAGCATTCTACAACCCCAGACCACCGTTAATCCAGATCGCATCAAACA
AACATTGCCATCTTCCCCAACTACCACCAAGTCCTCTCCATCTGATCCCATGACCACCTCCAGAGCTAATCAGGTGACCAAGAATATGGC
CCAGGTGACCAAAGCCCTGGACAAGGCCCTGAGCACCATGGACCTGCAGAAGGTCTCCTCAGTGATGGACAGGTTCGAGCAGCAGGTGCA
GAACCTGGACGTCCATACATCGGTGATGGAGGACTCCATGAGCTCGGCCACCACCCTGACCACGCCGCAGGAGCAGGTGGACAGCCTCAT
CATGCAGATCGCCGAGGAGAATGGCCTGGAGGTGCTGGACCAGCTCAGCCAGCTGCCCGAGGGCGCCTCTGCCGTGGGCGAGAGCTCTGT
GCGCAGCCAGGAGGACCAGCTGTCACGGAGGTTGGCCGCCTTGAGGAACTAGCCGTGCCCCGCCGGTGTGCACCGCCTCTGCCCCGTGAT
GTGCTGGAAGGCTCCTGTCCTCTCCCCACCGCGTCTTGCCTTTGTGCTGACCCCGCGGGGCTGCGGCCGGCAGCCACTCTGCGTCTCTCA
CCTGCCAGGCCTGCGTGGCCTTAGGGTTGTTCCTGTTCTTTTAGGTTGGGCGGTGGGTCTGTGTCCTGGTGTTGAGTTTCTGCAAATTTC
TGGGGGTGATTTCTGTGACTCTGGGCCCACAGCGGGGAGGCCAAGAGGGGCCCTGTGGACTTTCACCCAGCACTGTGGGGGCCTTCAGAC
TCTGGGGCAGCAGACATGCTGCTTCCCATCAGCCAGAGGGGGTCAGGGCTGCCCTGTTGCCAAACAACTCCCTGAGGCCTCTCCGCACCA
CCTCAGCGGGCAGGAGGTCCCACCATGTGGACAGACATAGCCCAAGGAGGCACCACAGGTCTATGTGTGCTGGGGGATGTCAGGTGCCAC
CCAACGCTGTCCTGGTGGTATTTACAATGACATCCTCCTCCTCCATCACTCCAGGGGTGGTGTCTCGGCCGCCCCTACCAGCTGGCTGAG
CCCCCTGGCCTCCTGCGCTCCCTCACTTCCCTCAGTTCCCAAAGCTGCCCAGTCCATGGGGACAGAACCGTCACTCAGATCCACATTCAA
GTGTGCCCACCCTGCAGTCTTCATCCTCACTCAGCTGCTGCCTCTGGAGGTGCCTTTGGCCACATGTGCTGTGCTGTTTGTCTCCTCGAC
AGGGAGCCTGTCCACCAGCAGGCTGCGGTCCCAGCGGGTGCGTCTGCAGCTCCTCCCCTTGGGCAGCCTGGTTCTCCCGGAGGACCTTTC
CTTGGGGCCCTGCTTCATGACGATGCTGCCTGTGTCACCCTCTACCATCTGTAAACAACTGGGTGCCTTCCCCGACCACACCCCAATGCC
TTCCCAGCTTGGAAGCCAAGGCAGCTGATGAAGGGAGCTCAGGAGAGCCGTCTTCAGCTGGGCTGGGGTTGGGGCTGCTGTGAGGAAAAC
CTGCCATTGTGGCCCTGGAGAGTCACCAGCAGCTCTTGGGAAGGACTTGCTGGGAGGCTGAGAGAGGCTTTGGGCACAGCCTGCTGTCTT
TTCCATTTCCTAAAGTTTACTTCATTGTCTTGAGGCTTCCAGGTTTTGTTTTTGTTTTTGCCAAAGTAGAAAAGGCAGGTGGTGGGCGGC
TGGCAGGGAGTGCGGGTCCCCGCCCCTCTTCAGTCCTGCCCTCCCCTCCTCAGTCCTGCCCACCCCGTGCAGCCCATGCTGAGGCTGCAG
TGGTGTCGTGGGTGTTACGTGCAGGAACGTGGAGACCCTGACGTGGGCTCACTGCGTTTGGTTTTCTTTTCAGAACTTGGGAGCCCCCAG
GGAGGGGCTAGTGTTGGTAGGTCCTAGACGTGGTTCCCTCCAGCCTCCCCAAAATCAACCCTGGTGTTGAGAGAACGTCCTTCTGTCCAT
CGTGGGTAACAGCCTTGGGGAGGGTGCAGAGCTCTGCAGAGCCATGGGCCAGGTGGGGCTGCCTCAGTCCTGTCCCCTTGGGCACTGAGG

>59795_59795_1_NOVA1-CHMP1A_NOVA1_chr14_26941526_ENST00000344429_CHMP1A_chr16_89713739_ENST00000397901_length(amino acids)=285AA_BP=172
MMAAAPIQQNGTHTGVPIDLDPPDSRKRPLEAPPEAGSTKRTNTGEDGQYFLKVLIPSYAAGSIIGKGGQTIVQLQKETGATIKLSKSKD
FYPGTTERVCLIQGTVEALNAVHGFIAEKIREMPQNVAKTEPVSILQPQTTVNPDRIKQTLPSSPTTTKSSPSDPMTTSRANQVTKNMAQ
VTKALDKALSTMDLQKVSSVMDRFEQQVQNLDVHTSVMEDSMSSATTLTTPQEQVDSLIMQIAEENGLEVLDQLSQLPEGASAVGESSVR

--------------------------------------------------------------
>59795_59795_2_NOVA1-CHMP1A_NOVA1_chr14_26941526_ENST00000344429_CHMP1A_chr16_89713739_ENST00000535997_length(transcript)=2465nt_BP=523nt
AAACATGATGGCGGCAGCTCCCATCCAGCAGAACGGGACCCACACTGGGGTTCCCATAGACCTGGACCCGCCGGACTCGCGGAAAAGGCC
GCTGGAAGCCCCCCCTGAAGCCGGCAGCACCAAGAGGACCAATACGGGCGAAGACGGCCAGTATTTTCTAAAGGTTCTCATACCTAGTTA
TGCTGCTGGATCTATAATTGGGAAGGGAGGACAGACAATTGTTCAGTTGCAAAAAGAAACTGGAGCCACCATCAAGCTGTCTAAGTCCAA
AGATTTTTACCCAGGTACTACTGAGCGAGTGTGCTTGATCCAGGGAACGGTTGAAGCACTGAATGCAGTTCATGGATTCATTGCAGAAAA
AATTCGAGAAATGCCCCAAAATGTGGCCAAGACAGAACCAGTCAGCATTCTACAACCCCAGACCACCGTTAATCCAGATCGCATCAAACA
AACATTGCCATCTTCCCCAACTACCACCAAGTCCTCTCCATCTGATCCCATGACCACCTCCAGAGCTAATCAGGTGACCAAGAATATGGC
CCAGGTGACCAAAGCCCTGGACAAGGCCCTGAGCACCATGGACCTGCAGAAGGTCTCCTCAGTGATGGACAGGTTCGAGCAGCAGGTGCA
GAACCTGGACGTCCATACATCGGTGATGGAGGACTCCATGAGCTCGGCCACCACCCTGACCACGCCGCAGGAGCAGGTGGACAGCCTCAT
CATGCAGATCGCCGAGGAGAATGGCCTGGAGGTGCTGGACCAGCTCAGCCAGCTGCCCGAGGGCGCCTCTGCCGTGGGCGAGAGCTCTGT
GCGCAGCCAGGAGGACCAGCTGTCACGGAGGTTGGCCGCCTTGAGGAACTAGCCGTGCCCCGCCGGTGTGCACCGCCTCTGCCCCGTGAT
GTGCTGGAAGGCTCCTGTCCTCTCCCCACCGCGTCTTGCCTTTGTGCTGACCCCGCGGGGCTGCGGCCGGCAGCCACTCTGCGTCTCTCA
CCTGCCAGGCCTGCGTGGCCTTAGGGTTGTTCCTGTTCTTTTAGGTTGGGCGGTGGGTCTGTGTCCTGGTGTTGAGTTTCTGCAAATTTC
TGGGGGTGATTTCTGTGACTCTGGGCCCACAGCGGGGAGGCCAAGAGGGGCCCTGTGGACTTTCACCCAGCACTGTGGGGGCCTTCAGAC
TCTGGGGCAGCAGACATGCTGCTTCCCATCAGCCAGAGGGGGTCAGGGCTGCCCTGTTGCCAAACAACTCCCTGAGGCCTCTCCGCACCA
CCTCAGCGGGCAGGAGGTCCCACCATGTGGACAGACATAGCCCAAGGAGGCACCACAGGTCTATGTGTGCTGGGGGATGTCAGGTGCCAC
CCAACGCTGTCCTGGTGGTATTTACAATGACATCCTCCTCCTCCATCACTCCAGGGGTGGTGTCTCGGCCGCCCCTACCAGCTGGCTGAG
CCCCCTGGCCTCCTGCGCTCCCTCACTTCCCTCAGTTCCCAAAGCTGCCCAGTCCATGGGGACAGAACCGTCACTCAGATCCACATTCAA
GTGTGCCCACCCTGCAGTCTTCATCCTCACTCAGCTGCTGCCTCTGGAGGTGCCTTTGGCCACATGTGCTGTGCTGTTTGTCTCCTCGAC
AGGGAGCCTGTCCACCAGCAGGCTGCGGTCCCAGCGGGTGCGTCTGCAGCTCCTCCCCTTGGGCAGCCTGGTTCTCCCGGAGGACCTTTC
CTTGGGGCCCTGCTTCATGACGATGCTGCCTGTGTCACCCTCTACCATCTGTAAACAACTGGGTGCCTTCCCCGACCACACCCCAATGCC
TTCCCAGCTTGGAAGCCAAGGCAGCTGATGAAGGGAGCTCAGGAGAGCCGTCTTCAGCTGGGCTGGGGTTGGGGCTGCTGTGAGGAAAAC
CTGCCATTGTGGCCCTGGAGAGTCACCAGCAGCTCTTGGGAAGGACTTGCTGGGAGGCTGAGAGAGGCTTTGGGCACAGCCTGCTGTCTT
TTCCATTTCCTAAAGTTTACTTCATTGTCTTGAGGCTTCCAGGTTTTGTTTTTGTTTTTGCCAAAGTAGAAAAGGCAGGTGGTGGGCGGC
TGGCAGGGAGTGCGGGTCCCCGCCCCTCTTCAGTCCTGCCCTCCCCTCCTCAGTCCTGCCCACCCCGTGCAGCCCATGCTGAGGCTGCAG
TGGTGTCGTGGGTGTTACGTGCAGGAACGTGGAGACCCTGACGTGGGCTCACTGCGTTTGGTTTTCTTTTCAGAACTTGGGAGCCCCCAG
GGAGGGGCTAGTGTTGGTAGGTCCTAGACGTGGTTCCCTCCAGCCTCCCCAAAATCAACCCTGGTGTTGAGAGAACGTCCTTCTGTCCAT
CGTGGGTAACAGCCTTGGGGAGGGTGCAGAGCTCTGCAGAGCCATGGGCCAGGTGGGGCTGCCTCAGTCCTGTCCCCTTGGGCACTGAGG

>59795_59795_2_NOVA1-CHMP1A_NOVA1_chr14_26941526_ENST00000344429_CHMP1A_chr16_89713739_ENST00000535997_length(amino acids)=285AA_BP=172
MMAAAPIQQNGTHTGVPIDLDPPDSRKRPLEAPPEAGSTKRTNTGEDGQYFLKVLIPSYAAGSIIGKGGQTIVQLQKETGATIKLSKSKD
FYPGTTERVCLIQGTVEALNAVHGFIAEKIREMPQNVAKTEPVSILQPQTTVNPDRIKQTLPSSPTTTKSSPSDPMTTSRANQVTKNMAQ
VTKALDKALSTMDLQKVSSVMDRFEQQVQNLDVHTSVMEDSMSSATTLTTPQEQVDSLIMQIAEENGLEVLDQLSQLPEGASAVGESSVR

--------------------------------------------------------------
>59795_59795_3_NOVA1-CHMP1A_NOVA1_chr14_26941526_ENST00000344429_CHMP1A_chr16_89713739_ENST00000550102_length(transcript)=1039nt_BP=523nt
AAACATGATGGCGGCAGCTCCCATCCAGCAGAACGGGACCCACACTGGGGTTCCCATAGACCTGGACCCGCCGGACTCGCGGAAAAGGCC
GCTGGAAGCCCCCCCTGAAGCCGGCAGCACCAAGAGGACCAATACGGGCGAAGACGGCCAGTATTTTCTAAAGGTTCTCATACCTAGTTA
TGCTGCTGGATCTATAATTGGGAAGGGAGGACAGACAATTGTTCAGTTGCAAAAAGAAACTGGAGCCACCATCAAGCTGTCTAAGTCCAA
AGATTTTTACCCAGGTACTACTGAGCGAGTGTGCTTGATCCAGGGAACGGTTGAAGCACTGAATGCAGTTCATGGATTCATTGCAGAAAA
AATTCGAGAAATGCCCCAAAATGTGGCCAAGACAGAACCAGTCAGCATTCTACAACCCCAGACCACCGTTAATCCAGATCGCATCAAACA
AACATTGCCATCTTCCCCAACTACCACCAAGTCCTCTCCATCTGATCCCATGACCACCTCCAGAGCTAATCAGGTGACCAAGAATATGGC
CCAGGTGACCAAAGCCCTGGACAAGGCCCTGAGCACCATGGACCTGCAGAAGGTCTCCTCAGTGATGGACAGGTTCGAGCAGCAGGTGCA
GAACCTGGACGTCCATACATCGGTGATGGAGGACTCCATGAGCTCGGCCACCACCCTGACCACGCCGCAGGAGCAGGTGGACAGCCTCAT
CATGCAGATCGCCGAGGAGAATGGCCTGGAGGTGCTGGACCAGCTCAGCCAGCTGCCCGAGGGCGCCTCTGCCGTGGGCGAGAGCTCTGT
GCGCAGCCAGGAGGACCAGCTGTCACGGAGGTTGGCCGCCTTGAGGAACTAGCCGTGCCCCGCCGGTGTGCACCGCCTCTGCCCCGTGAT
GTGCTGGAAGGCTCCTGTCCTCTCCCCACCGCGTCTTGCCTTTGTGCTGACCCCGCGGGGCTGCGGCCGGCAGCCACTCTGCGTCTCTCA

>59795_59795_3_NOVA1-CHMP1A_NOVA1_chr14_26941526_ENST00000344429_CHMP1A_chr16_89713739_ENST00000550102_length(amino acids)=285AA_BP=172
MMAAAPIQQNGTHTGVPIDLDPPDSRKRPLEAPPEAGSTKRTNTGEDGQYFLKVLIPSYAAGSIIGKGGQTIVQLQKETGATIKLSKSKD
FYPGTTERVCLIQGTVEALNAVHGFIAEKIREMPQNVAKTEPVSILQPQTTVNPDRIKQTLPSSPTTTKSSPSDPMTTSRANQVTKNMAQ
VTKALDKALSTMDLQKVSSVMDRFEQQVQNLDVHTSVMEDSMSSATTLTTPQEQVDSLIMQIAEENGLEVLDQLSQLPEGASAVGESSVR

--------------------------------------------------------------
>59795_59795_4_NOVA1-CHMP1A_NOVA1_chr14_26941526_ENST00000539517_CHMP1A_chr16_89713739_ENST00000397901_length(transcript)=2811nt_BP=837nt
CTCTCCCTTCTCCACTCTCTCCCCCTGTCTCCTTTCTTCTTCTTCTTTCACCCTCCGTCTCTCACACCCCCTCCATTCCCCTGTCTCCTT
TCTGACACTGCACTGCAGCTGCTCCTCAGCCCTGCCCCCTCCCCAGTGAGAACAAACCAGCAACATTGCTTTTTTTCCTAAAGAGATTTA
TATTGATCCGATTAAAAAAAAAAAACCTTAAGAAACCCCAAACGCAAAAAAAAAAAAAAAAAAAAAAGAAAAAAGAAAAGAAAAAGCCAA
AACAAAAGGGAGAACCTTCTCCCGGTAGCAGCGGCAGGAACTGCAAACATGATGGCGGCAGCTCCCATCCAGCAGAACGGGACCCACACT
GGGGTTCCCATAGACCTGGACCCGCCGGACTCGCGGAAAAGGCCGCTGGAAGCCCCCCCTGAAGCCGGCAGCACCAAGAGGACCAATACG
GGCGAAGACGGCCAGTATTTTCTAAAGGTTCTCATACCTAGTTATGCTGCTGGATCTATAATTGGGAAGGGAGGACAGACAATTGTTCAG
TTGCAAAAAGAAACTGGAGCCACCATCAAGCTGTCTAAGTCCAAAGATTTTTACCCAGGTACTACTGAGCGAGTGTGCTTGATCCAGGGA
ACGGTTGAAGCACTGAATGCAGTTCATGGATTCATTGCAGAAAAAATTCGAGAAATGCCCCAAAATGTGGCCAAGACAGAACCAGTCAGC
ATTCTACAACCCCAGACCACCGTTAATCCAGATCGCATCAAACAAACATTGCCATCTTCCCCAACTACCACCAAGTCCTCTCCATCTGAT
CCCATGACCACCTCCAGAGCTAATCAGGTGACCAAGAATATGGCCCAGGTGACCAAAGCCCTGGACAAGGCCCTGAGCACCATGGACCTG
CAGAAGGTCTCCTCAGTGATGGACAGGTTCGAGCAGCAGGTGCAGAACCTGGACGTCCATACATCGGTGATGGAGGACTCCATGAGCTCG
GCCACCACCCTGACCACGCCGCAGGAGCAGGTGGACAGCCTCATCATGCAGATCGCCGAGGAGAATGGCCTGGAGGTGCTGGACCAGCTC
AGCCAGCTGCCCGAGGGCGCCTCTGCCGTGGGCGAGAGCTCTGTGCGCAGCCAGGAGGACCAGCTGTCACGGAGGTTGGCCGCCTTGAGG
AACTAGCCGTGCCCCGCCGGTGTGCACCGCCTCTGCCCCGTGATGTGCTGGAAGGCTCCTGTCCTCTCCCCACCGCGTCTTGCCTTTGTG
CTGACCCCGCGGGGCTGCGGCCGGCAGCCACTCTGCGTCTCTCACCTGCCAGGCCTGCGTGGCCTTAGGGTTGTTCCTGTTCTTTTAGGT
TGGGCGGTGGGTCTGTGTCCTGGTGTTGAGTTTCTGCAAATTTCTGGGGGTGATTTCTGTGACTCTGGGCCCACAGCGGGGAGGCCAAGA
GGGGCCCTGTGGACTTTCACCCAGCACTGTGGGGGCCTTCAGACTCTGGGGCAGCAGACATGCTGCTTCCCATCAGCCAGAGGGGGTCAG
GGCTGCCCTGTTGCCAAACAACTCCCTGAGGCCTCTCCGCACCACCTCAGCGGGCAGGAGGTCCCACCATGTGGACAGACATAGCCCAAG
GAGGCACCACAGGTCTATGTGTGCTGGGGGATGTCAGGTGCCACCCAACGCTGTCCTGGTGGTATTTACAATGACATCCTCCTCCTCCAT
CACTCCAGGGGTGGTGTCTCGGCCGCCCCTACCAGCTGGCTGAGCCCCCTGGCCTCCTGCGCTCCCTCACTTCCCTCAGTTCCCAAAGCT
GCCCAGTCCATGGGGACAGAACCGTCACTCAGATCCACATTCAAGTGTGCCCACCCTGCAGTCTTCATCCTCACTCAGCTGCTGCCTCTG
GAGGTGCCTTTGGCCACATGTGCTGTGCTGTTTGTCTCCTCGACAGGGAGCCTGTCCACCAGCAGGCTGCGGTCCCAGCGGGTGCGTCTG
CAGCTCCTCCCCTTGGGCAGCCTGGTTCTCCCGGAGGACCTTTCCTTGGGGCCCTGCTTCATGACGATGCTGCCTGTGTCACCCTCTACC
ATCTGTAAACAACTGGGTGCCTTCCCCGACCACACCCCAATGCCTTCCCAGCTTGGAAGCCAAGGCAGCTGATGAAGGGAGCTCAGGAGA
GCCGTCTTCAGCTGGGCTGGGGTTGGGGCTGCTGTGAGGAAAACCTGCCATTGTGGCCCTGGAGAGTCACCAGCAGCTCTTGGGAAGGAC
TTGCTGGGAGGCTGAGAGAGGCTTTGGGCACAGCCTGCTGTCTTTTCCATTTCCTAAAGTTTACTTCATTGTCTTGAGGCTTCCAGGTTT
TGTTTTTGTTTTTGCCAAAGTAGAAAAGGCAGGTGGTGGGCGGCTGGCAGGGAGTGCGGGTCCCCGCCCCTCTTCAGTCCTGCCCTCCCC
TCCTCAGTCCTGCCCACCCCGTGCAGCCCATGCTGAGGCTGCAGTGGTGTCGTGGGTGTTACGTGCAGGAACGTGGAGACCCTGACGTGG
GCTCACTGCGTTTGGTTTTCTTTTCAGAACTTGGGAGCCCCCAGGGAGGGGCTAGTGTTGGTAGGTCCTAGACGTGGTTCCCTCCAGCCT
CCCCAAAATCAACCCTGGTGTTGAGAGAACGTCCTTCTGTCCATCGTGGGTAACAGCCTTGGGGAGGGTGCAGAGCTCTGCAGAGCCATG
GGCCAGGTGGGGCTGCCTCAGTCCTGTCCCCTTGGGCACTGAGGAGAGGGGCCCATTCACCTTTCTCCTAGAATGCTGTTGTAAATAAAC

>59795_59795_4_NOVA1-CHMP1A_NOVA1_chr14_26941526_ENST00000539517_CHMP1A_chr16_89713739_ENST00000397901_length(amino acids)=285AA_BP=172
MMAAAPIQQNGTHTGVPIDLDPPDSRKRPLEAPPEAGSTKRTNTGEDGQYFLKVLIPSYAAGSIIGKGGQTIVQLQKETGATIKLSKSKD
FYPGTTERVCLIQGTVEALNAVHGFIAEKIREMPQNVAKTEPVSILQPQTTVNPDRIKQTLPSSPTTTKSSPSDPMTTSRANQVTKNMAQ
VTKALDKALSTMDLQKVSSVMDRFEQQVQNLDVHTSVMEDSMSSATTLTTPQEQVDSLIMQIAEENGLEVLDQLSQLPEGASAVGESSVR

--------------------------------------------------------------
>59795_59795_5_NOVA1-CHMP1A_NOVA1_chr14_26941526_ENST00000539517_CHMP1A_chr16_89713739_ENST00000535997_length(transcript)=2779nt_BP=837nt
CTCTCCCTTCTCCACTCTCTCCCCCTGTCTCCTTTCTTCTTCTTCTTTCACCCTCCGTCTCTCACACCCCCTCCATTCCCCTGTCTCCTT
TCTGACACTGCACTGCAGCTGCTCCTCAGCCCTGCCCCCTCCCCAGTGAGAACAAACCAGCAACATTGCTTTTTTTCCTAAAGAGATTTA
TATTGATCCGATTAAAAAAAAAAAACCTTAAGAAACCCCAAACGCAAAAAAAAAAAAAAAAAAAAAAGAAAAAAGAAAAGAAAAAGCCAA
AACAAAAGGGAGAACCTTCTCCCGGTAGCAGCGGCAGGAACTGCAAACATGATGGCGGCAGCTCCCATCCAGCAGAACGGGACCCACACT
GGGGTTCCCATAGACCTGGACCCGCCGGACTCGCGGAAAAGGCCGCTGGAAGCCCCCCCTGAAGCCGGCAGCACCAAGAGGACCAATACG
GGCGAAGACGGCCAGTATTTTCTAAAGGTTCTCATACCTAGTTATGCTGCTGGATCTATAATTGGGAAGGGAGGACAGACAATTGTTCAG
TTGCAAAAAGAAACTGGAGCCACCATCAAGCTGTCTAAGTCCAAAGATTTTTACCCAGGTACTACTGAGCGAGTGTGCTTGATCCAGGGA
ACGGTTGAAGCACTGAATGCAGTTCATGGATTCATTGCAGAAAAAATTCGAGAAATGCCCCAAAATGTGGCCAAGACAGAACCAGTCAGC
ATTCTACAACCCCAGACCACCGTTAATCCAGATCGCATCAAACAAACATTGCCATCTTCCCCAACTACCACCAAGTCCTCTCCATCTGAT
CCCATGACCACCTCCAGAGCTAATCAGGTGACCAAGAATATGGCCCAGGTGACCAAAGCCCTGGACAAGGCCCTGAGCACCATGGACCTG
CAGAAGGTCTCCTCAGTGATGGACAGGTTCGAGCAGCAGGTGCAGAACCTGGACGTCCATACATCGGTGATGGAGGACTCCATGAGCTCG
GCCACCACCCTGACCACGCCGCAGGAGCAGGTGGACAGCCTCATCATGCAGATCGCCGAGGAGAATGGCCTGGAGGTGCTGGACCAGCTC
AGCCAGCTGCCCGAGGGCGCCTCTGCCGTGGGCGAGAGCTCTGTGCGCAGCCAGGAGGACCAGCTGTCACGGAGGTTGGCCGCCTTGAGG
AACTAGCCGTGCCCCGCCGGTGTGCACCGCCTCTGCCCCGTGATGTGCTGGAAGGCTCCTGTCCTCTCCCCACCGCGTCTTGCCTTTGTG
CTGACCCCGCGGGGCTGCGGCCGGCAGCCACTCTGCGTCTCTCACCTGCCAGGCCTGCGTGGCCTTAGGGTTGTTCCTGTTCTTTTAGGT
TGGGCGGTGGGTCTGTGTCCTGGTGTTGAGTTTCTGCAAATTTCTGGGGGTGATTTCTGTGACTCTGGGCCCACAGCGGGGAGGCCAAGA
GGGGCCCTGTGGACTTTCACCCAGCACTGTGGGGGCCTTCAGACTCTGGGGCAGCAGACATGCTGCTTCCCATCAGCCAGAGGGGGTCAG
GGCTGCCCTGTTGCCAAACAACTCCCTGAGGCCTCTCCGCACCACCTCAGCGGGCAGGAGGTCCCACCATGTGGACAGACATAGCCCAAG
GAGGCACCACAGGTCTATGTGTGCTGGGGGATGTCAGGTGCCACCCAACGCTGTCCTGGTGGTATTTACAATGACATCCTCCTCCTCCAT
CACTCCAGGGGTGGTGTCTCGGCCGCCCCTACCAGCTGGCTGAGCCCCCTGGCCTCCTGCGCTCCCTCACTTCCCTCAGTTCCCAAAGCT
GCCCAGTCCATGGGGACAGAACCGTCACTCAGATCCACATTCAAGTGTGCCCACCCTGCAGTCTTCATCCTCACTCAGCTGCTGCCTCTG
GAGGTGCCTTTGGCCACATGTGCTGTGCTGTTTGTCTCCTCGACAGGGAGCCTGTCCACCAGCAGGCTGCGGTCCCAGCGGGTGCGTCTG
CAGCTCCTCCCCTTGGGCAGCCTGGTTCTCCCGGAGGACCTTTCCTTGGGGCCCTGCTTCATGACGATGCTGCCTGTGTCACCCTCTACC
ATCTGTAAACAACTGGGTGCCTTCCCCGACCACACCCCAATGCCTTCCCAGCTTGGAAGCCAAGGCAGCTGATGAAGGGAGCTCAGGAGA
GCCGTCTTCAGCTGGGCTGGGGTTGGGGCTGCTGTGAGGAAAACCTGCCATTGTGGCCCTGGAGAGTCACCAGCAGCTCTTGGGAAGGAC
TTGCTGGGAGGCTGAGAGAGGCTTTGGGCACAGCCTGCTGTCTTTTCCATTTCCTAAAGTTTACTTCATTGTCTTGAGGCTTCCAGGTTT
TGTTTTTGTTTTTGCCAAAGTAGAAAAGGCAGGTGGTGGGCGGCTGGCAGGGAGTGCGGGTCCCCGCCCCTCTTCAGTCCTGCCCTCCCC
TCCTCAGTCCTGCCCACCCCGTGCAGCCCATGCTGAGGCTGCAGTGGTGTCGTGGGTGTTACGTGCAGGAACGTGGAGACCCTGACGTGG
GCTCACTGCGTTTGGTTTTCTTTTCAGAACTTGGGAGCCCCCAGGGAGGGGCTAGTGTTGGTAGGTCCTAGACGTGGTTCCCTCCAGCCT
CCCCAAAATCAACCCTGGTGTTGAGAGAACGTCCTTCTGTCCATCGTGGGTAACAGCCTTGGGGAGGGTGCAGAGCTCTGCAGAGCCATG

>59795_59795_5_NOVA1-CHMP1A_NOVA1_chr14_26941526_ENST00000539517_CHMP1A_chr16_89713739_ENST00000535997_length(amino acids)=285AA_BP=172
MMAAAPIQQNGTHTGVPIDLDPPDSRKRPLEAPPEAGSTKRTNTGEDGQYFLKVLIPSYAAGSIIGKGGQTIVQLQKETGATIKLSKSKD
FYPGTTERVCLIQGTVEALNAVHGFIAEKIREMPQNVAKTEPVSILQPQTTVNPDRIKQTLPSSPTTTKSSPSDPMTTSRANQVTKNMAQ
VTKALDKALSTMDLQKVSSVMDRFEQQVQNLDVHTSVMEDSMSSATTLTTPQEQVDSLIMQIAEENGLEVLDQLSQLPEGASAVGESSVR

--------------------------------------------------------------
>59795_59795_6_NOVA1-CHMP1A_NOVA1_chr14_26941526_ENST00000539517_CHMP1A_chr16_89713739_ENST00000550102_length(transcript)=1353nt_BP=837nt
CTCTCCCTTCTCCACTCTCTCCCCCTGTCTCCTTTCTTCTTCTTCTTTCACCCTCCGTCTCTCACACCCCCTCCATTCCCCTGTCTCCTT
TCTGACACTGCACTGCAGCTGCTCCTCAGCCCTGCCCCCTCCCCAGTGAGAACAAACCAGCAACATTGCTTTTTTTCCTAAAGAGATTTA
TATTGATCCGATTAAAAAAAAAAAACCTTAAGAAACCCCAAACGCAAAAAAAAAAAAAAAAAAAAAAGAAAAAAGAAAAGAAAAAGCCAA
AACAAAAGGGAGAACCTTCTCCCGGTAGCAGCGGCAGGAACTGCAAACATGATGGCGGCAGCTCCCATCCAGCAGAACGGGACCCACACT
GGGGTTCCCATAGACCTGGACCCGCCGGACTCGCGGAAAAGGCCGCTGGAAGCCCCCCCTGAAGCCGGCAGCACCAAGAGGACCAATACG
GGCGAAGACGGCCAGTATTTTCTAAAGGTTCTCATACCTAGTTATGCTGCTGGATCTATAATTGGGAAGGGAGGACAGACAATTGTTCAG
TTGCAAAAAGAAACTGGAGCCACCATCAAGCTGTCTAAGTCCAAAGATTTTTACCCAGGTACTACTGAGCGAGTGTGCTTGATCCAGGGA
ACGGTTGAAGCACTGAATGCAGTTCATGGATTCATTGCAGAAAAAATTCGAGAAATGCCCCAAAATGTGGCCAAGACAGAACCAGTCAGC
ATTCTACAACCCCAGACCACCGTTAATCCAGATCGCATCAAACAAACATTGCCATCTTCCCCAACTACCACCAAGTCCTCTCCATCTGAT
CCCATGACCACCTCCAGAGCTAATCAGGTGACCAAGAATATGGCCCAGGTGACCAAAGCCCTGGACAAGGCCCTGAGCACCATGGACCTG
CAGAAGGTCTCCTCAGTGATGGACAGGTTCGAGCAGCAGGTGCAGAACCTGGACGTCCATACATCGGTGATGGAGGACTCCATGAGCTCG
GCCACCACCCTGACCACGCCGCAGGAGCAGGTGGACAGCCTCATCATGCAGATCGCCGAGGAGAATGGCCTGGAGGTGCTGGACCAGCTC
AGCCAGCTGCCCGAGGGCGCCTCTGCCGTGGGCGAGAGCTCTGTGCGCAGCCAGGAGGACCAGCTGTCACGGAGGTTGGCCGCCTTGAGG
AACTAGCCGTGCCCCGCCGGTGTGCACCGCCTCTGCCCCGTGATGTGCTGGAAGGCTCCTGTCCTCTCCCCACCGCGTCTTGCCTTTGTG
CTGACCCCGCGGGGCTGCGGCCGGCAGCCACTCTGCGTCTCTCACCTGCCAGGCCTGCGTGGCCTTAGGGTTGTTCCTGTTCTTTTAGGT

>59795_59795_6_NOVA1-CHMP1A_NOVA1_chr14_26941526_ENST00000539517_CHMP1A_chr16_89713739_ENST00000550102_length(amino acids)=285AA_BP=172
MMAAAPIQQNGTHTGVPIDLDPPDSRKRPLEAPPEAGSTKRTNTGEDGQYFLKVLIPSYAAGSIIGKGGQTIVQLQKETGATIKLSKSKD
FYPGTTERVCLIQGTVEALNAVHGFIAEKIREMPQNVAKTEPVSILQPQTTVNPDRIKQTLPSSPTTTKSSPSDPMTTSRANQVTKNMAQ
VTKALDKALSTMDLQKVSSVMDRFEQQVQNLDVHTSVMEDSMSSATTLTTPQEQVDSLIMQIAEENGLEVLDQLSQLPEGASAVGESSVR

--------------------------------------------------------------

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Fusion Gene PPI Analysis for NOVA1-CHMP1A


check button Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in

ChiPPI page.


check button Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160)
HgeneHgene's interactorsTgeneTgene's interactors


check button - Retained PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenStill interaction with


check button - Lost PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


check button - Retained PPIs, but lost function due to frame-shift fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


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Related Drugs for NOVA1-CHMP1A


check button Drugs targeting genes involved in this fusion gene.
(DrugBank Version 5.1.8 2021-05-08)
PartnerGeneUniProtAccDrugBank IDDrug nameDrug activityDrug typeDrug status

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Related Diseases for NOVA1-CHMP1A


check button Diseases associated with fusion partners.
(DisGeNet 4.0)
PartnerGeneDisease IDDisease name# pubmedsSource