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Center for Computational Systems Medicine
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Fusion Gene Summary

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Fusion Gene ORF analysis

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Fusion Genomic Features

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Fusion Protein Features

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Fusion Gene Sequence

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Fusion Gene PPI analysis

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Related Drugs

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Related Diseases

Fusion gene:NPLOC4-PLCE1 (FusionGDB2 ID:59956)

Fusion Gene Summary for NPLOC4-PLCE1

check button Fusion gene summary
Fusion gene informationFusion gene name: NPLOC4-PLCE1
Fusion gene ID: 59956
HgeneTgene
Gene symbol

NPLOC4

PLCE1

Gene ID

55666

51196

Gene nameNPL4 homolog, ubiquitin recognition factorphospholipase C epsilon 1
SynonymsNPL4NPHS3|PLCE|PPLC
Cytomap

17q25.3

10q23.33

Type of geneprotein-codingprotein-coding
Descriptionnuclear protein localization protein 4 homologNPLOC4 ubiquitin recognition factornuclear protein localization 4 homolog1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase epsilon-1PLC-epsilon-1pancreas-enriched phospholipase Cphosphoinositide phospholipase Cphosphoinositide phospholipase C-epsilon-1phosphoinositide-specific phospholipase C epsilon-1
Modification date2020031320200313
UniProtAcc

Q8TAT6

.
Ensembl transtripts involved in fusion geneENST00000331134, ENST00000374747, 
ENST00000574344, ENST00000539314, 
ENST00000572760, ENST00000573876, 
ENST00000464214, ENST00000260766, 
ENST00000371375, ENST00000371380, 
ENST00000371385, 
Fusion gene scores* DoF score19 X 17 X 11=35537 X 8 X 6=336
# samples 308
** MAII scorelog2(30/3553*10)=-3.56600328283534
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0		log2(8/336*10)=-2.0703893278914
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0
Context

PubMed: NPLOC4 [Title/Abstract] AND PLCE1 [Title/Abstract] AND fusion [Title/Abstract]

Most frequent breakpointNPLOC4(79577235)-PLCE1(96081657), # samples:1
Anticipated loss of major functional domain due to fusion event.
* DoF score (Degree of Frequency) = # partners X # break points X # cancer types
** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)

check button Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez
PartnerGeneGO IDGO termPubMed ID
TgenePLCE1

GO:0000187

activation of MAPK activity

11022047

TgenePLCE1

GO:0007200

phospholipase C-activating G protein-coupled receptor signaling pathway

11022047|11022048

TgenePLCE1

GO:0007265

Ras protein signal transduction

11022048

TgenePLCE1

GO:0008277

regulation of G protein-coupled receptor signaling pathway

11022047

TgenePLCE1

GO:0045859

regulation of protein kinase activity

11022047

TgenePLCE1

GO:0046578

regulation of Ras protein signal transduction

11022047


check buttonFusion gene breakpoints across NPLOC4 (5'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check buttonFusion gene breakpoints across PLCE1 (3'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check button Fusion gene information from two resources (ChiTars 5.0 and ChimerDB 4.0)
* All genome coordinats were lifted-over on hg19.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
SourceDiseaseSampleHgeneHchrHbpHstrandTgeneTchrTbpTstrand
ChimerDB4OVTCGA-59-2363NPLOC4chr17

79577235

-PLCE1chr10

96081657

+


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Fusion Gene ORF analysis for NPLOC4-PLCE1

check button Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
ORFHenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrand
5CDS-intronENST00000331134ENST00000464214NPLOC4chr17

79577235

-PLCE1chr10

96081657

+
5CDS-intronENST00000374747ENST00000464214NPLOC4chr17

79577235

-PLCE1chr10

96081657

+
5UTR-3CDSENST00000574344ENST00000260766NPLOC4chr17

79577235

-PLCE1chr10

96081657

+
5UTR-3CDSENST00000574344ENST00000371375NPLOC4chr17

79577235

-PLCE1chr10

96081657

+
5UTR-3CDSENST00000574344ENST00000371380NPLOC4chr17

79577235

-PLCE1chr10

96081657

+
5UTR-3CDSENST00000574344ENST00000371385NPLOC4chr17

79577235

-PLCE1chr10

96081657

+
5UTR-intronENST00000574344ENST00000464214NPLOC4chr17

79577235

-PLCE1chr10

96081657

+
In-frameENST00000331134ENST00000260766NPLOC4chr17

79577235

-PLCE1chr10

96081657

+
In-frameENST00000331134ENST00000371375NPLOC4chr17

79577235

-PLCE1chr10

96081657

+
In-frameENST00000331134ENST00000371380NPLOC4chr17

79577235

-PLCE1chr10

96081657

+
In-frameENST00000331134ENST00000371385NPLOC4chr17

79577235

-PLCE1chr10

96081657

+
In-frameENST00000374747ENST00000260766NPLOC4chr17

79577235

-PLCE1chr10

96081657

+
In-frameENST00000374747ENST00000371375NPLOC4chr17

79577235

-PLCE1chr10

96081657

+
In-frameENST00000374747ENST00000371380NPLOC4chr17

79577235

-PLCE1chr10

96081657

+
In-frameENST00000374747ENST00000371385NPLOC4chr17

79577235

-PLCE1chr10

96081657

+
intron-3CDSENST00000539314ENST00000260766NPLOC4chr17

79577235

-PLCE1chr10

96081657

+
intron-3CDSENST00000539314ENST00000371375NPLOC4chr17

79577235

-PLCE1chr10

96081657

+
intron-3CDSENST00000539314ENST00000371380NPLOC4chr17

79577235

-PLCE1chr10

96081657

+
intron-3CDSENST00000539314ENST00000371385NPLOC4chr17

79577235

-PLCE1chr10

96081657

+
intron-3CDSENST00000572760ENST00000260766NPLOC4chr17

79577235

-PLCE1chr10

96081657

+
intron-3CDSENST00000572760ENST00000371375NPLOC4chr17

79577235

-PLCE1chr10

96081657

+
intron-3CDSENST00000572760ENST00000371380NPLOC4chr17

79577235

-PLCE1chr10

96081657

+
intron-3CDSENST00000572760ENST00000371385NPLOC4chr17

79577235

-PLCE1chr10

96081657

+
intron-3CDSENST00000573876ENST00000260766NPLOC4chr17

79577235

-PLCE1chr10

96081657

+
intron-3CDSENST00000573876ENST00000371375NPLOC4chr17

79577235

-PLCE1chr10

96081657

+
intron-3CDSENST00000573876ENST00000371380NPLOC4chr17

79577235

-PLCE1chr10

96081657

+
intron-3CDSENST00000573876ENST00000371385NPLOC4chr17

79577235

-PLCE1chr10

96081657

+
intron-intronENST00000539314ENST00000464214NPLOC4chr17

79577235

-PLCE1chr10

96081657

+
intron-intronENST00000572760ENST00000464214NPLOC4chr17

79577235

-PLCE1chr10

96081657

+
intron-intronENST00000573876ENST00000464214NPLOC4chr17

79577235

-PLCE1chr10

96081657

+

check buttonORFfinder result based on the fusion transcript sequence of in-frame fusion genes.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandSeq length
(transcript)		BP loci
(transcript)		Predicted start
(transcript)		Predicted stop
(transcript)		Seq length
(amino acids)
ENST00000331134NPLOC4chr1779577235-ENST00000260766PLCE1chr1096081657+166765131217404
ENST00000331134NPLOC4chr1779577235-ENST00000371380PLCE1chr1096081657+609865131217404
ENST00000331134NPLOC4chr1779577235-ENST00000371385PLCE1chr1096081657+166765131217404
ENST00000331134NPLOC4chr1779577235-ENST00000371375PLCE1chr1096081657+174765131217404
ENST00000374747NPLOC4chr1779577235-ENST00000260766PLCE1chr1096081657+158156511131376
ENST00000374747NPLOC4chr1779577235-ENST00000371380PLCE1chr1096081657+601256511131376
ENST00000374747NPLOC4chr1779577235-ENST00000371385PLCE1chr1096081657+158156511131376
ENST00000374747NPLOC4chr1779577235-ENST00000371375PLCE1chr1096081657+166156511131376

check buttonDeepORF prediction of the coding potential based on the fusion transcript sequence of in-frame fusion genes. DeepORF is a coding potential classifier based on convolutional neural network by comparing the real Ribo-seq data. If the no-coding score < 0.5 and coding score > 0.5, then the in-frame fusion transcript is predicted as being likely translated.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandNo-coding scoreCoding score
ENST00000331134ENST00000260766NPLOC4chr1779577235-PLCE1chr1096081657+0.0046275130.9953725
ENST00000331134ENST00000371380NPLOC4chr1779577235-PLCE1chr1096081657+0.000506160.99949384
ENST00000331134ENST00000371385NPLOC4chr1779577235-PLCE1chr1096081657+0.0046275130.9953725
ENST00000331134ENST00000371375NPLOC4chr1779577235-PLCE1chr1096081657+0.0080433970.9919566
ENST00000374747ENST00000260766NPLOC4chr1779577235-PLCE1chr1096081657+0.0036496380.9963503
ENST00000374747ENST00000371380NPLOC4chr1779577235-PLCE1chr1096081657+0.0004902370.9995098
ENST00000374747ENST00000371385NPLOC4chr1779577235-PLCE1chr1096081657+0.0036496380.9963503
ENST00000374747ENST00000371375NPLOC4chr1779577235-PLCE1chr1096081657+0.0071889740.992811

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Fusion Genomic Features for NPLOC4-PLCE1


check buttonFusionAI prediction of the potential fusion gene breakpoint based on the pre-mature RNA sequence context (+/- 5kb of individual partner genes, total 20kb length sequence). FusionAI is a fusion gene breakpoint classifier based on convolutional neural network by comparing the fusion positive and negative sequence context of ~ 20K fusion gene data. From here, we can have the relative potentency of the 20K genomic sequence how individual sequnce will be likely used as the gene fusion breakpoints.
HgeneHchrHbpHstrandTgeneTchrTbpTstrand1-pp (fusion gene breakpoint)
NPLOC4chr1779577235-PLCE1chr1096081657+2.07E-070.99999976
NPLOC4chr1779577235-PLCE1chr1096081657+2.07E-070.99999976

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions. We integrated a total of 44 different types of human genomic feature loci information across five big categories including virus integration sites, repeats, structural variants, chromatin states, and gene expression regulation. More details are in help page.
genomic feature

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions that are ovelapped with the top 1% feature importance score regions. More details are in help page.
genomic feature of top 1%

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Fusion Protein Features for NPLOC4-PLCE1


check button Four levels of functional features of fusion genes
Go to FGviewer search page for the most frequent breakpoint (https://ccsmweb.uth.edu/FGviewer/chr17:79577235/chr10:96081657)
- FGviewer provides the online visualization of the retention search of the protein functional features across DNA, RNA, protein, and pathological levels.
- How to search
1. Put your fusion gene symbol.
2. Press the tab key until there will be shown the breakpoint information filled.
4. Go down and press 'Search' tab twice.
4. Go down to have the hyperlink of the search result.
5. Click the hyperlink.
6. See the FGviewer result for your fusion gene.
FGviewer

check buttonMain function of each fusion partner protein. (from UniProt)
HgeneTgene
NPLOC4

Q8TAT6

.
FUNCTION: The ternary complex containing UFD1, VCP and NPLOC4 binds ubiquitinated proteins and is necessary for the export of misfolded proteins from the ER to the cytoplasm, where they are degraded by the proteasome. The NPLOC4-UFD1-VCP complex regulates spindle disassembly at the end of mitosis and is necessary for the formation of a closed nuclear envelope (By similarity). Acts as a negative regulator of type I interferon production via the complex formed with VCP and UFD1, which binds to DDX58/RIG-I and recruits RNF125 to promote ubiquitination and degradation of DDX58/RIG-I (PubMed:26471729). {ECO:0000250|UniProtKB:Q9ES54, ECO:0000269|PubMed:26471729}.FUNCTION: Transcriptional activator which is required for calcium-dependent dendritic growth and branching in cortical neurons. Recruits CREB-binding protein (CREBBP) to nuclear bodies. Component of the CREST-BRG1 complex, a multiprotein complex that regulates promoter activation by orchestrating a calcium-dependent release of a repressor complex and a recruitment of an activator complex. In resting neurons, transcription of the c-FOS promoter is inhibited by BRG1-dependent recruitment of a phospho-RB1-HDAC1 repressor complex. Upon calcium influx, RB1 is dephosphorylated by calcineurin, which leads to release of the repressor complex. At the same time, there is increased recruitment of CREBBP to the promoter by a CREST-dependent mechanism, which leads to transcriptional activation. The CREST-BRG1 complex also binds to the NR2B promoter, and activity-dependent induction of NR2B expression involves a release of HDAC1 and recruitment of CREBBP (By similarity). {ECO:0000250}.

check buttonRetention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at

download page


* Minus value of BPloci means that the break pointn is located before the CDS.
- In-frame and retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
TgenePLCE1chr17:79577235chr10:96081657ENST0000026076628332135_223821142354.6666666666665DomainRas-associating 2
TgenePLCE1chr17:79577235chr10:96081657ENST0000037137527311851_197618061995.0DomainC2
TgenePLCE1chr17:79577235chr10:96081657ENST0000037137527312012_211418061995.0DomainRas-associating 1
TgenePLCE1chr17:79577235chr10:96081657ENST0000037137527312135_223818061995.0DomainRas-associating 2
TgenePLCE1chr17:79577235chr10:96081657ENST0000037138027322135_223821143441.3333333333335DomainRas-associating 2
TgenePLCE1chr17:79577235chr10:96081657ENST0000037138527321851_197618062035.3333333333333DomainC2
TgenePLCE1chr17:79577235chr10:96081657ENST0000037138527322012_211418062035.3333333333333DomainRas-associating 1
TgenePLCE1chr17:79577235chr10:96081657ENST0000037138527322135_223818062035.3333333333333DomainRas-associating 2

- In-frame and not-retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneNPLOC4chr17:79577235chr10:96081657ENST00000331134-517226_363145609.0DomainMPN
HgeneNPLOC4chr17:79577235chr10:96081657ENST00000374747-516226_363145618.0DomainMPN
HgeneNPLOC4chr17:79577235chr10:96081657ENST00000331134-517580_608145609.0Zinc fingerRanBP2-type
HgeneNPLOC4chr17:79577235chr10:96081657ENST00000374747-516580_608145618.0Zinc fingerRanBP2-type
TgenePLCE1chr17:79577235chr10:96081657ENST0000026076628331392_154021142354.6666666666665DomainPI-PLC X-box
TgenePLCE1chr17:79577235chr10:96081657ENST0000026076628331730_184621142354.6666666666665DomainPI-PLC Y-box
TgenePLCE1chr17:79577235chr10:96081657ENST0000026076628331851_197621142354.6666666666665DomainC2
TgenePLCE1chr17:79577235chr10:96081657ENST0000026076628332012_211421142354.6666666666665DomainRas-associating 1
TgenePLCE1chr17:79577235chr10:96081657ENST000002607662833531_79021142354.6666666666665DomainRas-GEF
TgenePLCE1chr17:79577235chr10:96081657ENST0000037137527311392_154018061995.0DomainPI-PLC X-box
TgenePLCE1chr17:79577235chr10:96081657ENST0000037137527311730_184618061995.0DomainPI-PLC Y-box
TgenePLCE1chr17:79577235chr10:96081657ENST000003713752731531_79018061995.0DomainRas-GEF
TgenePLCE1chr17:79577235chr10:96081657ENST0000037138027321392_154021143441.3333333333335DomainPI-PLC X-box
TgenePLCE1chr17:79577235chr10:96081657ENST0000037138027321730_184621143441.3333333333335DomainPI-PLC Y-box
TgenePLCE1chr17:79577235chr10:96081657ENST0000037138027321851_197621143441.3333333333335DomainC2
TgenePLCE1chr17:79577235chr10:96081657ENST0000037138027322012_211421143441.3333333333335DomainRas-associating 1
TgenePLCE1chr17:79577235chr10:96081657ENST000003713802732531_79021143441.3333333333335DomainRas-GEF
TgenePLCE1chr17:79577235chr10:96081657ENST0000037138527321392_154018062035.3333333333333DomainPI-PLC X-box
TgenePLCE1chr17:79577235chr10:96081657ENST0000037138527321730_184618062035.3333333333333DomainPI-PLC Y-box
TgenePLCE1chr17:79577235chr10:96081657ENST000003713852732531_79018062035.3333333333333DomainRas-GEF
TgenePLCE1chr17:79577235chr10:96081657ENST0000026076628331686_176421142354.6666666666665RegionRequired for activation by RHOA%2C RHOB%2C GNA12%2C GNA13 and G-beta gamma
TgenePLCE1chr17:79577235chr10:96081657ENST0000037137527311686_176418061995.0RegionRequired for activation by RHOA%2C RHOB%2C GNA12%2C GNA13 and G-beta gamma
TgenePLCE1chr17:79577235chr10:96081657ENST0000037138027321686_176421143441.3333333333335RegionRequired for activation by RHOA%2C RHOB%2C GNA12%2C GNA13 and G-beta gamma
TgenePLCE1chr17:79577235chr10:96081657ENST0000037138527321686_176418062035.3333333333333RegionRequired for activation by RHOA%2C RHOB%2C GNA12%2C GNA13 and G-beta gamma


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Fusion Gene Sequence for NPLOC4-PLCE1


check button For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. To have fusion amino acid sequence, we ran ORFfinder and chose the longest ORF among the all predicted ones.
>59956_59956_1_NPLOC4-PLCE1_NPLOC4_chr17_79577235_ENST00000331134_PLCE1_chr10_96081657_ENST00000260766_length(transcript)=1667nt_BP=651nt
AACCTGGTTTCCCGGCCTCGCGCCCGAGGGGAGCGTATTGAGCGAGGCACCGGGACGTCGGCGGCTGGCGGAGCCGGGCGGGCGAAGCTG
GAGCGGCGGTGGCGGCGGCGTAGGGAGGCCGGGGCCGGGGCTGAGGCCGCGGCCGGGTCTGCGAGGCCCTTGGGGCGGCAGGCGGCGGCG
GCCCGGGGCTCGAGCCCGGAGGCAGGAGCAGCCGCCATGGCCGAGAGCATCATAATTCGTGTCCAGTCCCCGGATGGAGTGAAGCGGATC
ACAGCAACAAAGAGAGAAACAGCAGCAACATTTTTGAAAAAGGTTGCAAAGGAGTTTGGCTTCCAAAATAATGGCTTCTCGGTTTACATC
AATAGAAACAAGACCGGAGAGATAACAGCCTCCTCCAACAAATCCCTCAACTTGCTAAAAATCAAGCATGGCGATTTGTTGTTCCTGTTT
CCCTCGAGCCTTGCTGGGCCCTCATCTGAAATGGAGACGTCAGTTCCACCGGGCTTCAAAGTCTTTGGCGCTCCCAACGTGGTGGAGGAT
GAGATTGATCAGTACCTCAGCAAACAGGACGGGAAGATTTACAGAAGCCGAGACCCACAGCTATGCCGCCACGGCCCTTTGGGGAAATGC
GTGCACTGCGTCCCTCTAGAGAACCTAGAAGAGAAAAACATTGTTCAAGATGACAAAGAGGTGATCTTGAGCTCAGAGGAGGAGAGTTTC
TTTGTCCAAGTGCATGATGTTTCTCCAGAGCAACCTCGAACAGTCATCAAAGCACCCCGCGTCAGCACTGCACAGGATGTCATTCAGCAG
ACCTTATGCAAAGCCAAATATTCCTACAGCATCCTGAGCAACCCCAATCCAAGCGACTATGTGCTTTTGGAAGAGGTGGTGAAAGACACT
ACCAACAAGAAGACTACCACACCAAAGTCCTCTCAGCGGGTCCTTCTGGATCAGGAGTGTGTGTTTCAAGCCCAAAGCAAGTGGAAAGGT
GCAGGAAAATTCATCCTTAAGCTAAAGGAGCAGGTGCAGGCATCTCGAGAAGATAAAAAGAAAGGCATTTCTTTCGCAAGTGAACTCAAG
AAGCTCACCAAGTCAACTAAACAGCCCCGAGGACTTACATCACCTTCTCAGCTCTTGACCTCAGAAAGTATCCAAACCAAGGAGGAGAAA
CCTGTGGGTGGCTTGTCCTCCAGTGACACAATGGATTACCGACAGTGACTAAGGGCAGCATGTTTAACCCAGGTGAAGATCTTTAAGCAA
GAAGTTAAAGAGTGAACATGGTGGAAAAAATATAATTATTTTCATCAGACTTAAACTGGAAATTGATGATTTCTGAACTGAAGCCTTCAC
ACATGTGAGATCCATGCTGAGGAGAAGCAAAATGGCACAGGGCTAGTTGCCACCAACCAATTTACTGATGAATGAAGCCCAGGGGACTGC
CATTTTATAAATGTCAGCAGTTGGAAAAATCGTCACGAATTGACTTAGAGCAAGGGTCAGCAAGCTTGTCTGTAAAGGGCCAAACAGTAA
ATATTTTAGGGCTGGGGGCCATAAAATATGTTGCAACCACCCAATTCTGCCATTGTAGTGCAAAAGCAGCCATAGACAACACATACATGA

>59956_59956_1_NPLOC4-PLCE1_NPLOC4_chr17_79577235_ENST00000331134_PLCE1_chr10_96081657_ENST00000260766_length(amino acids)=404AA_BP=216
MVSRPRARGERIERGTGTSAAGGAGRAKLERRWRRRREAGAGAEAAAGSARPLGRQAAAARGSSPEAGAAAMAESIIIRVQSPDGVKRIT
ATKRETAATFLKKVAKEFGFQNNGFSVYINRNKTGEITASSNKSLNLLKIKHGDLLFLFPSSLAGPSSEMETSVPPGFKVFGAPNVVEDE
IDQYLSKQDGKIYRSRDPQLCRHGPLGKCVHCVPLENLEEKNIVQDDKEVILSSEEESFFVQVHDVSPEQPRTVIKAPRVSTAQDVIQQT
LCKAKYSYSILSNPNPSDYVLLEEVVKDTTNKKTTTPKSSQRVLLDQECVFQAQSKWKGAGKFILKLKEQVQASREDKKKGISFASELKK

--------------------------------------------------------------
>59956_59956_2_NPLOC4-PLCE1_NPLOC4_chr17_79577235_ENST00000331134_PLCE1_chr10_96081657_ENST00000371375_length(transcript)=1747nt_BP=651nt
AACCTGGTTTCCCGGCCTCGCGCCCGAGGGGAGCGTATTGAGCGAGGCACCGGGACGTCGGCGGCTGGCGGAGCCGGGCGGGCGAAGCTG
GAGCGGCGGTGGCGGCGGCGTAGGGAGGCCGGGGCCGGGGCTGAGGCCGCGGCCGGGTCTGCGAGGCCCTTGGGGCGGCAGGCGGCGGCG
GCCCGGGGCTCGAGCCCGGAGGCAGGAGCAGCCGCCATGGCCGAGAGCATCATAATTCGTGTCCAGTCCCCGGATGGAGTGAAGCGGATC
ACAGCAACAAAGAGAGAAACAGCAGCAACATTTTTGAAAAAGGTTGCAAAGGAGTTTGGCTTCCAAAATAATGGCTTCTCGGTTTACATC
AATAGAAACAAGACCGGAGAGATAACAGCCTCCTCCAACAAATCCCTCAACTTGCTAAAAATCAAGCATGGCGATTTGTTGTTCCTGTTT
CCCTCGAGCCTTGCTGGGCCCTCATCTGAAATGGAGACGTCAGTTCCACCGGGCTTCAAAGTCTTTGGCGCTCCCAACGTGGTGGAGGAT
GAGATTGATCAGTACCTCAGCAAACAGGACGGGAAGATTTACAGAAGCCGAGACCCACAGCTATGCCGCCACGGCCCTTTGGGGAAATGC
GTGCACTGCGTCCCTCTAGAGAACCTAGAAGAGAAAAACATTGTTCAAGATGACAAAGAGGTGATCTTGAGCTCAGAGGAGGAGAGTTTC
TTTGTCCAAGTGCATGATGTTTCTCCAGAGCAACCTCGAACAGTCATCAAAGCACCCCGCGTCAGCACTGCACAGGATGTCATTCAGCAG
ACCTTATGCAAAGCCAAATATTCCTACAGCATCCTGAGCAACCCCAATCCAAGCGACTATGTGCTTTTGGAAGAGGTGGTGAAAGACACT
ACCAACAAGAAGACTACCACACCAAAGTCCTCTCAGCGGGTCCTTCTGGATCAGGAGTGTGTGTTTCAAGCCCAAAGCAAGTGGAAAGGT
GCAGGAAAATTCATCCTTAAGCTAAAGGAGCAGGTGCAGGCATCTCGAGAAGATAAAAAGAAAGGCATTTCTTTCGCAAGTGAACTCAAG
AAGCTCACCAAGTCAACTAAACAGCCCCGAGGACTTACATCACCTTCTCAGCTCTTGACCTCAGAAAGTATCCAAACCAAGGAGGAGAAA
CCTGTGGGTGGCTTGTCCTCCAGTGACACAATGGATTACCGACAGTGACTAAGGGCAGCATGTTTAACCCAGGTATAGTAAGTCATTGCA
CCATCCTGGAACAGGGCTTAACTTAAACTACTTTGTAAGGAAGGCATAATTAGTACAATGTCTTTTATCTTTTCCAACAGGAGGATGTCC
CTTGAAGGCAGGTAGGAATGGGACCTTAAAACAGGAAAAGGGCTCTGAAGATATGTGTAACATGATATGCTATTGAACACCGCCTATAAA
GAAAAAGGGAAAGAGGCTGGGCGTGGTGGCGCATGCCTGTAATCCCAGCACTTTGGGAGGCCAAGGCAGGCAGATCACCTGAGGTCAGTT
CAAGACCAGCCTGACCAACATGGAGAAACCCCGTCTCTACTAAAAATACAAAATTAGCTGGGCATGGTGGTGCATGCCTATAATCCCAGC
TACTGGGGAGGCTGAGGCAGGAGAATCACTTGAACTTGGAAGGCAGAGGTTGCAGTGAGCTGAGATCACACCATTGCACTCCAGCCTGGG

>59956_59956_2_NPLOC4-PLCE1_NPLOC4_chr17_79577235_ENST00000331134_PLCE1_chr10_96081657_ENST00000371375_length(amino acids)=404AA_BP=216
MVSRPRARGERIERGTGTSAAGGAGRAKLERRWRRRREAGAGAEAAAGSARPLGRQAAAARGSSPEAGAAAMAESIIIRVQSPDGVKRIT
ATKRETAATFLKKVAKEFGFQNNGFSVYINRNKTGEITASSNKSLNLLKIKHGDLLFLFPSSLAGPSSEMETSVPPGFKVFGAPNVVEDE
IDQYLSKQDGKIYRSRDPQLCRHGPLGKCVHCVPLENLEEKNIVQDDKEVILSSEEESFFVQVHDVSPEQPRTVIKAPRVSTAQDVIQQT
LCKAKYSYSILSNPNPSDYVLLEEVVKDTTNKKTTTPKSSQRVLLDQECVFQAQSKWKGAGKFILKLKEQVQASREDKKKGISFASELKK

--------------------------------------------------------------
>59956_59956_3_NPLOC4-PLCE1_NPLOC4_chr17_79577235_ENST00000331134_PLCE1_chr10_96081657_ENST00000371380_length(transcript)=6098nt_BP=651nt
AACCTGGTTTCCCGGCCTCGCGCCCGAGGGGAGCGTATTGAGCGAGGCACCGGGACGTCGGCGGCTGGCGGAGCCGGGCGGGCGAAGCTG
GAGCGGCGGTGGCGGCGGCGTAGGGAGGCCGGGGCCGGGGCTGAGGCCGCGGCCGGGTCTGCGAGGCCCTTGGGGCGGCAGGCGGCGGCG
GCCCGGGGCTCGAGCCCGGAGGCAGGAGCAGCCGCCATGGCCGAGAGCATCATAATTCGTGTCCAGTCCCCGGATGGAGTGAAGCGGATC
ACAGCAACAAAGAGAGAAACAGCAGCAACATTTTTGAAAAAGGTTGCAAAGGAGTTTGGCTTCCAAAATAATGGCTTCTCGGTTTACATC
AATAGAAACAAGACCGGAGAGATAACAGCCTCCTCCAACAAATCCCTCAACTTGCTAAAAATCAAGCATGGCGATTTGTTGTTCCTGTTT
CCCTCGAGCCTTGCTGGGCCCTCATCTGAAATGGAGACGTCAGTTCCACCGGGCTTCAAAGTCTTTGGCGCTCCCAACGTGGTGGAGGAT
GAGATTGATCAGTACCTCAGCAAACAGGACGGGAAGATTTACAGAAGCCGAGACCCACAGCTATGCCGCCACGGCCCTTTGGGGAAATGC
GTGCACTGCGTCCCTCTAGAGAACCTAGAAGAGAAAAACATTGTTCAAGATGACAAAGAGGTGATCTTGAGCTCAGAGGAGGAGAGTTTC
TTTGTCCAAGTGCATGATGTTTCTCCAGAGCAACCTCGAACAGTCATCAAAGCACCCCGCGTCAGCACTGCACAGGATGTCATTCAGCAG
ACCTTATGCAAAGCCAAATATTCCTACAGCATCCTGAGCAACCCCAATCCAAGCGACTATGTGCTTTTGGAAGAGGTGGTGAAAGACACT
ACCAACAAGAAGACTACCACACCAAAGTCCTCTCAGCGGGTCCTTCTGGATCAGGAGTGTGTGTTTCAAGCCCAAAGCAAGTGGAAAGGT
GCAGGAAAATTCATCCTTAAGCTAAAGGAGCAGGTGCAGGCATCTCGAGAAGATAAAAAGAAAGGCATTTCTTTCGCAAGTGAACTCAAG
AAGCTCACCAAGTCAACTAAACAGCCCCGAGGACTTACATCACCTTCTCAGCTCTTGACCTCAGAAAGTATCCAAACCAAGGAGGAGAAA
CCTGTGGGTGGCTTGTCCTCCAGTGACACAATGGATTACCGACAGTGACTAAGGGCAGCATGTTTAACCCAGGTGAAGATCTTTAAGCAA
GAAGTTAAAGAGTGAACATGGTGGAAAAAATATAATTATTTTCATCAGACTTAAACTGGAAATTGATGATTTCTGAACTGAAGCCTTCAC
ACATGTGAGATCCATGCTGAGGAGAAGCAAAATGGCACAGGGCTAGTTGCCACCAACCAATTTACTGATGAATGAAGCCCAGGGGACTGC
CATTTTATAAATGTCAGCAGTTGGAAAAATCGTCACGAATTGACTTAGAGCAAGGGTCAGCAAGCTTGTCTGTAAAGGGCCAAACAGTAA
ATATTTTAGGGCTGGGGGCCATAAAATATGTTGCAACCACCCAATTCTGCCATTGTAGTGCAAAAGCAGCCATAGACAACACATACATGA
ACGAACGTGGCTGTATTCCAATAAAACTTTATTTATGGACACTGAAATTGGAATTTCATATATTTTTCACATGTCACAAATACTCTTGTT
TTGACTTTTTTTCAACCATTTAAAAACTTAAAAACTATTCTTAATTCAGGGGCCATACAAAAACAGGTGGCAGGCTAGATTTGGCCCAAG
GACCTTAATTTGCCAACACAACTAAGAGAAGAGAACTGGGAACAAGGAGCACAAAGATCTGAAAACAGGAAAGGAAGTTTAGCCATACAT
TTTATGGCCGAGAATTAGAAGCTTAGAATTAGAAGCTTTGGGGCATTTCAAGTGTAAATATGTCCTATAACATAAGAGTCATTAAAATTC
AATTTAGTTCCTGTATTGTGTACCACAGTGCACTCCTCTTTAGGATTTTTTTACATATAGAAATAATATTGGGTTTTTTTTAAGGTTATT
GCCTATTCAGTTAATAGGGTTGCTTTAAAAAAGGTTATTGCTTAATCATAGATTAGATTACTCATTTTTGGTTTTCAAAATGAATTTAGA
ATGACGTATAATTTAATATCTACTGAATTGCAATGTCTTAACAAGAAACCTAACAATTTTTTAAAGCAAAAGTAGATTGAGTTGGCGTTT
AAATTTATTTTGCAAGGTTTGTACTGACACTATACTTATATATTTATTATACATCGCTCTCTTGATATTGCCATGGATTAGAAGCATTAG
TTCTCAGTACTTGAAGACAAACTTCTAAAAAGAAAATATATGCTCTGAACATCTGAAATGGGCTAGACTTTCAAGTAAAATTGCTTCATT
TCTCATTAACTGAAGAGCTATTGATCCAAGTCATACTTGCCATTTAATGTAAATTATTTTTAAACTTTGCTGTACAAAACCATTAAGTGT
AAAGGATTCTTCATATTCTTAGTATGAAGCAAATTATGAATTTTAAAAATGAAATATGTATTCCTCTAAAACCCAAACTTTTATCTTTCC
ATTGGTATCTTTGAATTTTAAGACACTTTTCTTCAAATTACAAAACACTAAAACTCACTCCTAAACTTCACTTTGAGAAACTTTTTTAAC
CAATTATAAAAATAAAACCATCCCCATGTGTTTCTTGCATATTCTAAAAACAGAAGTGTTAAAAATACACCACACAGGCTGGGCAGAGTG
GCTCACGCCTGTAACTCCAGCACTTTGGGAGGCCAAGATGGGCGGATCAGGACAGAGAATGAGGCCATCCTGGCCAACATGGTGAAACCC
AATCTCTACTAAAAGTACAAAAATTAGCTGAGCGTGGTGGCACGTGCCTGTAATCCCAGCTACTCGGGAGGCTGAGGCAGGAGAATCACT
TGAACCTGGGAGGTGGAGGCTGCAGTGAGCCAAGATCGCACCACCACGCTCCAGCCTGGTGACAGAGCGAGACTCCGTCTCAAAAAAAAA
AAAAAAAAAAAAAAAAAAAAAAAAAACACCATACAGCTTTCATGTCATTGAAAGTTCTTACTGGGTCAAAGCCTTAAGGCTAGAACTACC
ATTTTCTTGTCAACAGAATTCAGGCTATTCCAGTTTGATGTAATCTATACAGTAGTACAGTTTTAAGTCAAATATTCATTCTAACAAATG
CACAATGCTGCTCCATTTTAAAAATATTCCGGAAACACTTTATCAAGCCTCTATAAGTGAACATGCCAAACAGTTTGCCCTACCACGTGT
TGAAAACTGAGTTGCTGGTCTAAGTGGCTAGAGGCCAAATGAAAACTGTGCAGAGTAACAAGATGAAAAGACTCGTCTCTTTAGGTTTAT
CACATTTGATTCTGATGCTAAGCGCTGCCCCACTCCTCCTCCATGACCTTTAACACAGGTGTATGTTTTACAACATAAATCTGAGACTGA
AGTTGAGACCAGGTTGTTTAGCAAGTGAGAGAATCCAGCCTACTGCCTAGGTTGCATCCCAATTTAGTTGTTTATCACATTTTGAGGTGA
AAGTACATACTTCATTGTATTTGAGTCTTTGGGATTACAGAAAGAACACATTGTTTCAAAATGTAAAGAGTTGGCTGGGCACAGTGGCTC
ATGCCTGTAATCCCAACACTCTGGGAGGCTGAGGTGGGTGGATCACCTGAGGTCTGGAGTTCGAGGCCAACATGGTGAAACCCGTCTCTA
CTAAAAATACAAAAATTAGCTGGGTACTAAAAATACAAAAATTAGTGGTGGTGGGCACCTGTAAATCCCAGCTATTGGGGAGGCTGAGGC
AGGAGAGAATTGCCTGAACTCAAGACGCAGAGGTTGCAGTGAGTGGAGACTGTGCCACTGCACTCCAGCCTGGGTACAAGAGTGAGACTC
CATCTCAAAAAAAAAAAAAAAAAGTAAAGAGTCTAGTCTACTATTATACACAAATGGCCAGCACAATCTGATGTTGGCTGAAAATATTTA
AGTTTTATTTAAAGCTTTCTGAATTAAACAGCTATATTATGCCAAGTGAAAGAAATTATCCTAAATAGCCACTATGACTATACCCATTAC
CATTTCACACTTTTTAGGCCACCAGAAATCTGGGTAGCAAACTCTTCTCATTAAAGTTGATGTGGACAAGAATCTAAATATGCAAGTTGG
GGTCATTACAAAATTTTAAGAAGCATCACTGAAAGTGAAGAGAAAGGAGCATGAATTCTGTCACTCTATTCAGTGATGCCAAATCTGTAG
GAATGATCCTATCTGGGTAGAAAGTGCCCTTTGAGGGGTAAAGCTTCTTTTCATGTCATCATTAGCAAGTAAAAGTTATTTACAAATTCT
CCAGTTGGGAGTCAATATGAAGTCTAGACTCAACAAAAGTTGAGTTACAAGTGACTTGTTTTTAATCAAACTTGCTTTCTTTTATGGGAG
GCTTTTATGCCTCCCATCTCAATACCTCTGGAGACACTGGAAGCTCATTAATGAAAGTGGGCCCTCTATGATATGTATCAATTTACCTTT
TGCTAACTACATCGTCCCCTTCCTTTCTTCTCTCCTCTTCCAATATCTCTATAGACTTCTGTCCTCTGCCCAGAGACCCACAGGCCTTGC
TTAATTCTGGAAAGTTATCAGGGCTTGCTTACTGGCCCAATAAAATTGAATTAACTCTAAAACACAAAACTCCACATCTATGCTCCCATG
CTAGTAAAGAAGAGTAGGATTTTCCTGGCTGGTGTCTTTGATCTTACATTGGCAGCCTGCAGGGAAAGTGCTCTCATGGTGAAAGTCTCT
GACCCCTTTTCAGTTGCTTATATATCAGCAGTGAGGCCAGAAAAGATATACCTGGGACCCCAAAAAAGTTAGAGAGAAAAGGGAGATTGT
CTCTTATACAGAGTCTAGACTTGGGTCAATATTCCCCATGATCCATTGTTAATAATTTATGTGTTCTCTGCCATCCTTATGTAGCAGCTT
CCTAAAAGCAATCCTTGGCTGATGGCTATGGATTCTGACATAGGAATACCTGAAATGAGTCCCTTTGAAACACATACTGAGTCTCTATGA
TTACCAAGTTATTCTTTTTTTTTTTTTTTTTTTTGAGGCAAAGTCTCACTCTGTTGCCCAGCCTGGAGTGCAGTGGTACGATCTCGACTC
ACCACAACCTCCACCTCCCAGGTTCAAGTGATTCTCCTGCCTCAGCCTCCCAAGTAGCTGGGACTACAGGTGTGCGCCATGTCCGTCTAA
TTTTTTTTATTTTCAGTAGAGACGGGGGTTTCACTATGTTGGTAAGGCTGGTCTCGAACTCCTGACCTCGTGATCCACCCGCCTCAGCCT
CCCAAAGTGCTGGGATTACAGGCGTGAGCCACCACACCTGGCCTACCTACTCTTATACATCTCTTAGATTCAAAACATACTATGCACAAG
CCTGTCACCAAACAGATCTCTGAAACCTTCCCTATTGCAGATGACATAGGTCTCTAAACTTTTGACACAAGTAATTCTAACACTGAATTG
GGTACTGTCGCATTTTTCAAAAGCGTTATGTGGATGATTTGACTCAGCATGGAAGACTGAGGTTGTCTTACACCCATTATTTCCCACCCC
ACTCTTAAGTGCCAGCATAGTGCTAAACACACAGTAGGTGCTCATTATTTGTCTAGTTAAAAAACAAATTAAGGCTGTAGCTTAATATAG
CCTCAGGATATGTGTGTGCCTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTTTAAACATAAGCTTACATATAAGCGTA
TGTAAGTTAATGCACAAATATATTTCCTCAAATTCACATAGGATACTCAAATATAGATGTATAATTTTGTAGTCCCACTGTGATTCTCCA
TATGTATAACAAGAAAATTAAAGGCATAATACAGCTGTGAAATAGCTGATGAGTTTCTATTTTAAGCTGATTTTTCACCAGAAGTATAGT

>59956_59956_3_NPLOC4-PLCE1_NPLOC4_chr17_79577235_ENST00000331134_PLCE1_chr10_96081657_ENST00000371380_length(amino acids)=404AA_BP=216
MVSRPRARGERIERGTGTSAAGGAGRAKLERRWRRRREAGAGAEAAAGSARPLGRQAAAARGSSPEAGAAAMAESIIIRVQSPDGVKRIT
ATKRETAATFLKKVAKEFGFQNNGFSVYINRNKTGEITASSNKSLNLLKIKHGDLLFLFPSSLAGPSSEMETSVPPGFKVFGAPNVVEDE
IDQYLSKQDGKIYRSRDPQLCRHGPLGKCVHCVPLENLEEKNIVQDDKEVILSSEEESFFVQVHDVSPEQPRTVIKAPRVSTAQDVIQQT
LCKAKYSYSILSNPNPSDYVLLEEVVKDTTNKKTTTPKSSQRVLLDQECVFQAQSKWKGAGKFILKLKEQVQASREDKKKGISFASELKK

--------------------------------------------------------------
>59956_59956_4_NPLOC4-PLCE1_NPLOC4_chr17_79577235_ENST00000331134_PLCE1_chr10_96081657_ENST00000371385_length(transcript)=1667nt_BP=651nt
AACCTGGTTTCCCGGCCTCGCGCCCGAGGGGAGCGTATTGAGCGAGGCACCGGGACGTCGGCGGCTGGCGGAGCCGGGCGGGCGAAGCTG
GAGCGGCGGTGGCGGCGGCGTAGGGAGGCCGGGGCCGGGGCTGAGGCCGCGGCCGGGTCTGCGAGGCCCTTGGGGCGGCAGGCGGCGGCG
GCCCGGGGCTCGAGCCCGGAGGCAGGAGCAGCCGCCATGGCCGAGAGCATCATAATTCGTGTCCAGTCCCCGGATGGAGTGAAGCGGATC
ACAGCAACAAAGAGAGAAACAGCAGCAACATTTTTGAAAAAGGTTGCAAAGGAGTTTGGCTTCCAAAATAATGGCTTCTCGGTTTACATC
AATAGAAACAAGACCGGAGAGATAACAGCCTCCTCCAACAAATCCCTCAACTTGCTAAAAATCAAGCATGGCGATTTGTTGTTCCTGTTT
CCCTCGAGCCTTGCTGGGCCCTCATCTGAAATGGAGACGTCAGTTCCACCGGGCTTCAAAGTCTTTGGCGCTCCCAACGTGGTGGAGGAT
GAGATTGATCAGTACCTCAGCAAACAGGACGGGAAGATTTACAGAAGCCGAGACCCACAGCTATGCCGCCACGGCCCTTTGGGGAAATGC
GTGCACTGCGTCCCTCTAGAGAACCTAGAAGAGAAAAACATTGTTCAAGATGACAAAGAGGTGATCTTGAGCTCAGAGGAGGAGAGTTTC
TTTGTCCAAGTGCATGATGTTTCTCCAGAGCAACCTCGAACAGTCATCAAAGCACCCCGCGTCAGCACTGCACAGGATGTCATTCAGCAG
ACCTTATGCAAAGCCAAATATTCCTACAGCATCCTGAGCAACCCCAATCCAAGCGACTATGTGCTTTTGGAAGAGGTGGTGAAAGACACT
ACCAACAAGAAGACTACCACACCAAAGTCCTCTCAGCGGGTCCTTCTGGATCAGGAGTGTGTGTTTCAAGCCCAAAGCAAGTGGAAAGGT
GCAGGAAAATTCATCCTTAAGCTAAAGGAGCAGGTGCAGGCATCTCGAGAAGATAAAAAGAAAGGCATTTCTTTCGCAAGTGAACTCAAG
AAGCTCACCAAGTCAACTAAACAGCCCCGAGGACTTACATCACCTTCTCAGCTCTTGACCTCAGAAAGTATCCAAACCAAGGAGGAGAAA
CCTGTGGGTGGCTTGTCCTCCAGTGACACAATGGATTACCGACAGTGACTAAGGGCAGCATGTTTAACCCAGGTGAAGATCTTTAAGCAA
GAAGTTAAAGAGTGAACATGGTGGAAAAAATATAATTATTTTCATCAGACTTAAACTGGAAATTGATGATTTCTGAACTGAAGCCTTCAC
ACATGTGAGATCCATGCTGAGGAGAAGCAAAATGGCACAGGGCTAGTTGCCACCAACCAATTTACTGATGAATGAAGCCCAGGGGACTGC
CATTTTATAAATGTCAGCAGTTGGAAAAATCGTCACGAATTGACTTAGAGCAAGGGTCAGCAAGCTTGTCTGTAAAGGGCCAAACAGTAA
ATATTTTAGGGCTGGGGGCCATAAAATATGTTGCAACCACCCAATTCTGCCATTGTAGTGCAAAAGCAGCCATAGACAACACATACATGA

>59956_59956_4_NPLOC4-PLCE1_NPLOC4_chr17_79577235_ENST00000331134_PLCE1_chr10_96081657_ENST00000371385_length(amino acids)=404AA_BP=216
MVSRPRARGERIERGTGTSAAGGAGRAKLERRWRRRREAGAGAEAAAGSARPLGRQAAAARGSSPEAGAAAMAESIIIRVQSPDGVKRIT
ATKRETAATFLKKVAKEFGFQNNGFSVYINRNKTGEITASSNKSLNLLKIKHGDLLFLFPSSLAGPSSEMETSVPPGFKVFGAPNVVEDE
IDQYLSKQDGKIYRSRDPQLCRHGPLGKCVHCVPLENLEEKNIVQDDKEVILSSEEESFFVQVHDVSPEQPRTVIKAPRVSTAQDVIQQT
LCKAKYSYSILSNPNPSDYVLLEEVVKDTTNKKTTTPKSSQRVLLDQECVFQAQSKWKGAGKFILKLKEQVQASREDKKKGISFASELKK

--------------------------------------------------------------
>59956_59956_5_NPLOC4-PLCE1_NPLOC4_chr17_79577235_ENST00000374747_PLCE1_chr10_96081657_ENST00000260766_length(transcript)=1581nt_BP=565nt
GCTGGAGCGGCGGTGGCGGCGGCGTAGGGAGGCCGGGGCCGGGGCTGAGGCCGCGGCCGGGTCTGCGAGGCCCTTGGGGCGGCAGGCGGC
GGCGGCCCGGGGCTCGAGCCCGGAGGCAGGAGCAGCCGCCATGGCCGAGAGCATCATAATTCGTGTCCAGTCCCCGGATGGAGTGAAGCG
GATCACAGCAACAAAGAGAGAAACAGCAGCAACATTTTTGAAAAAGGTTGCAAAGGAGTTTGGCTTCCAAAATAATGGCTTCTCGGTTTA
CATCAATAGAAACAAGACCGGAGAGATAACAGCCTCCTCCAACAAATCCCTCAACTTGCTAAAAATCAAGCATGGCGATTTGTTGTTCCT
GTTTCCCTCGAGCCTTGCTGGGCCCTCATCTGAAATGGAGACGTCAGTTCCACCGGGCTTCAAAGTCTTTGGCGCTCCCAACGTGGTGGA
GGATGAGATTGATCAGTACCTCAGCAAACAGGACGGGAAGATTTACAGAAGCCGAGACCCACAGCTATGCCGCCACGGCCCTTTGGGGAA
ATGCGTGCACTGCGTCCCTCTAGAGAACCTAGAAGAGAAAAACATTGTTCAAGATGACAAAGAGGTGATCTTGAGCTCAGAGGAGGAGAG
TTTCTTTGTCCAAGTGCATGATGTTTCTCCAGAGCAACCTCGAACAGTCATCAAAGCACCCCGCGTCAGCACTGCACAGGATGTCATTCA
GCAGACCTTATGCAAAGCCAAATATTCCTACAGCATCCTGAGCAACCCCAATCCAAGCGACTATGTGCTTTTGGAAGAGGTGGTGAAAGA
CACTACCAACAAGAAGACTACCACACCAAAGTCCTCTCAGCGGGTCCTTCTGGATCAGGAGTGTGTGTTTCAAGCCCAAAGCAAGTGGAA
AGGTGCAGGAAAATTCATCCTTAAGCTAAAGGAGCAGGTGCAGGCATCTCGAGAAGATAAAAAGAAAGGCATTTCTTTCGCAAGTGAACT
CAAGAAGCTCACCAAGTCAACTAAACAGCCCCGAGGACTTACATCACCTTCTCAGCTCTTGACCTCAGAAAGTATCCAAACCAAGGAGGA
GAAACCTGTGGGTGGCTTGTCCTCCAGTGACACAATGGATTACCGACAGTGACTAAGGGCAGCATGTTTAACCCAGGTGAAGATCTTTAA
GCAAGAAGTTAAAGAGTGAACATGGTGGAAAAAATATAATTATTTTCATCAGACTTAAACTGGAAATTGATGATTTCTGAACTGAAGCCT
TCACACATGTGAGATCCATGCTGAGGAGAAGCAAAATGGCACAGGGCTAGTTGCCACCAACCAATTTACTGATGAATGAAGCCCAGGGGA
CTGCCATTTTATAAATGTCAGCAGTTGGAAAAATCGTCACGAATTGACTTAGAGCAAGGGTCAGCAAGCTTGTCTGTAAAGGGCCAAACA
GTAAATATTTTAGGGCTGGGGGCCATAAAATATGTTGCAACCACCCAATTCTGCCATTGTAGTGCAAAAGCAGCCATAGACAACACATAC

>59956_59956_5_NPLOC4-PLCE1_NPLOC4_chr17_79577235_ENST00000374747_PLCE1_chr10_96081657_ENST00000260766_length(amino acids)=376AA_BP=188
LERRWRRRREAGAGAEAAAGSARPLGRQAAAARGSSPEAGAAAMAESIIIRVQSPDGVKRITATKRETAATFLKKVAKEFGFQNNGFSVY
INRNKTGEITASSNKSLNLLKIKHGDLLFLFPSSLAGPSSEMETSVPPGFKVFGAPNVVEDEIDQYLSKQDGKIYRSRDPQLCRHGPLGK
CVHCVPLENLEEKNIVQDDKEVILSSEEESFFVQVHDVSPEQPRTVIKAPRVSTAQDVIQQTLCKAKYSYSILSNPNPSDYVLLEEVVKD
TTNKKTTTPKSSQRVLLDQECVFQAQSKWKGAGKFILKLKEQVQASREDKKKGISFASELKKLTKSTKQPRGLTSPSQLLTSESIQTKEE

--------------------------------------------------------------
>59956_59956_6_NPLOC4-PLCE1_NPLOC4_chr17_79577235_ENST00000374747_PLCE1_chr10_96081657_ENST00000371375_length(transcript)=1661nt_BP=565nt
GCTGGAGCGGCGGTGGCGGCGGCGTAGGGAGGCCGGGGCCGGGGCTGAGGCCGCGGCCGGGTCTGCGAGGCCCTTGGGGCGGCAGGCGGC
GGCGGCCCGGGGCTCGAGCCCGGAGGCAGGAGCAGCCGCCATGGCCGAGAGCATCATAATTCGTGTCCAGTCCCCGGATGGAGTGAAGCG
GATCACAGCAACAAAGAGAGAAACAGCAGCAACATTTTTGAAAAAGGTTGCAAAGGAGTTTGGCTTCCAAAATAATGGCTTCTCGGTTTA
CATCAATAGAAACAAGACCGGAGAGATAACAGCCTCCTCCAACAAATCCCTCAACTTGCTAAAAATCAAGCATGGCGATTTGTTGTTCCT
GTTTCCCTCGAGCCTTGCTGGGCCCTCATCTGAAATGGAGACGTCAGTTCCACCGGGCTTCAAAGTCTTTGGCGCTCCCAACGTGGTGGA
GGATGAGATTGATCAGTACCTCAGCAAACAGGACGGGAAGATTTACAGAAGCCGAGACCCACAGCTATGCCGCCACGGCCCTTTGGGGAA
ATGCGTGCACTGCGTCCCTCTAGAGAACCTAGAAGAGAAAAACATTGTTCAAGATGACAAAGAGGTGATCTTGAGCTCAGAGGAGGAGAG
TTTCTTTGTCCAAGTGCATGATGTTTCTCCAGAGCAACCTCGAACAGTCATCAAAGCACCCCGCGTCAGCACTGCACAGGATGTCATTCA
GCAGACCTTATGCAAAGCCAAATATTCCTACAGCATCCTGAGCAACCCCAATCCAAGCGACTATGTGCTTTTGGAAGAGGTGGTGAAAGA
CACTACCAACAAGAAGACTACCACACCAAAGTCCTCTCAGCGGGTCCTTCTGGATCAGGAGTGTGTGTTTCAAGCCCAAAGCAAGTGGAA
AGGTGCAGGAAAATTCATCCTTAAGCTAAAGGAGCAGGTGCAGGCATCTCGAGAAGATAAAAAGAAAGGCATTTCTTTCGCAAGTGAACT
CAAGAAGCTCACCAAGTCAACTAAACAGCCCCGAGGACTTACATCACCTTCTCAGCTCTTGACCTCAGAAAGTATCCAAACCAAGGAGGA
GAAACCTGTGGGTGGCTTGTCCTCCAGTGACACAATGGATTACCGACAGTGACTAAGGGCAGCATGTTTAACCCAGGTATAGTAAGTCAT
TGCACCATCCTGGAACAGGGCTTAACTTAAACTACTTTGTAAGGAAGGCATAATTAGTACAATGTCTTTTATCTTTTCCAACAGGAGGAT
GTCCCTTGAAGGCAGGTAGGAATGGGACCTTAAAACAGGAAAAGGGCTCTGAAGATATGTGTAACATGATATGCTATTGAACACCGCCTA
TAAAGAAAAAGGGAAAGAGGCTGGGCGTGGTGGCGCATGCCTGTAATCCCAGCACTTTGGGAGGCCAAGGCAGGCAGATCACCTGAGGTC
AGTTCAAGACCAGCCTGACCAACATGGAGAAACCCCGTCTCTACTAAAAATACAAAATTAGCTGGGCATGGTGGTGCATGCCTATAATCC
CAGCTACTGGGGAGGCTGAGGCAGGAGAATCACTTGAACTTGGAAGGCAGAGGTTGCAGTGAGCTGAGATCACACCATTGCACTCCAGCC

>59956_59956_6_NPLOC4-PLCE1_NPLOC4_chr17_79577235_ENST00000374747_PLCE1_chr10_96081657_ENST00000371375_length(amino acids)=376AA_BP=188
LERRWRRRREAGAGAEAAAGSARPLGRQAAAARGSSPEAGAAAMAESIIIRVQSPDGVKRITATKRETAATFLKKVAKEFGFQNNGFSVY
INRNKTGEITASSNKSLNLLKIKHGDLLFLFPSSLAGPSSEMETSVPPGFKVFGAPNVVEDEIDQYLSKQDGKIYRSRDPQLCRHGPLGK
CVHCVPLENLEEKNIVQDDKEVILSSEEESFFVQVHDVSPEQPRTVIKAPRVSTAQDVIQQTLCKAKYSYSILSNPNPSDYVLLEEVVKD
TTNKKTTTPKSSQRVLLDQECVFQAQSKWKGAGKFILKLKEQVQASREDKKKGISFASELKKLTKSTKQPRGLTSPSQLLTSESIQTKEE

--------------------------------------------------------------
>59956_59956_7_NPLOC4-PLCE1_NPLOC4_chr17_79577235_ENST00000374747_PLCE1_chr10_96081657_ENST00000371380_length(transcript)=6012nt_BP=565nt
GCTGGAGCGGCGGTGGCGGCGGCGTAGGGAGGCCGGGGCCGGGGCTGAGGCCGCGGCCGGGTCTGCGAGGCCCTTGGGGCGGCAGGCGGC
GGCGGCCCGGGGCTCGAGCCCGGAGGCAGGAGCAGCCGCCATGGCCGAGAGCATCATAATTCGTGTCCAGTCCCCGGATGGAGTGAAGCG
GATCACAGCAACAAAGAGAGAAACAGCAGCAACATTTTTGAAAAAGGTTGCAAAGGAGTTTGGCTTCCAAAATAATGGCTTCTCGGTTTA
CATCAATAGAAACAAGACCGGAGAGATAACAGCCTCCTCCAACAAATCCCTCAACTTGCTAAAAATCAAGCATGGCGATTTGTTGTTCCT
GTTTCCCTCGAGCCTTGCTGGGCCCTCATCTGAAATGGAGACGTCAGTTCCACCGGGCTTCAAAGTCTTTGGCGCTCCCAACGTGGTGGA
GGATGAGATTGATCAGTACCTCAGCAAACAGGACGGGAAGATTTACAGAAGCCGAGACCCACAGCTATGCCGCCACGGCCCTTTGGGGAA
ATGCGTGCACTGCGTCCCTCTAGAGAACCTAGAAGAGAAAAACATTGTTCAAGATGACAAAGAGGTGATCTTGAGCTCAGAGGAGGAGAG
TTTCTTTGTCCAAGTGCATGATGTTTCTCCAGAGCAACCTCGAACAGTCATCAAAGCACCCCGCGTCAGCACTGCACAGGATGTCATTCA
GCAGACCTTATGCAAAGCCAAATATTCCTACAGCATCCTGAGCAACCCCAATCCAAGCGACTATGTGCTTTTGGAAGAGGTGGTGAAAGA
CACTACCAACAAGAAGACTACCACACCAAAGTCCTCTCAGCGGGTCCTTCTGGATCAGGAGTGTGTGTTTCAAGCCCAAAGCAAGTGGAA
AGGTGCAGGAAAATTCATCCTTAAGCTAAAGGAGCAGGTGCAGGCATCTCGAGAAGATAAAAAGAAAGGCATTTCTTTCGCAAGTGAACT
CAAGAAGCTCACCAAGTCAACTAAACAGCCCCGAGGACTTACATCACCTTCTCAGCTCTTGACCTCAGAAAGTATCCAAACCAAGGAGGA
GAAACCTGTGGGTGGCTTGTCCTCCAGTGACACAATGGATTACCGACAGTGACTAAGGGCAGCATGTTTAACCCAGGTGAAGATCTTTAA
GCAAGAAGTTAAAGAGTGAACATGGTGGAAAAAATATAATTATTTTCATCAGACTTAAACTGGAAATTGATGATTTCTGAACTGAAGCCT
TCACACATGTGAGATCCATGCTGAGGAGAAGCAAAATGGCACAGGGCTAGTTGCCACCAACCAATTTACTGATGAATGAAGCCCAGGGGA
CTGCCATTTTATAAATGTCAGCAGTTGGAAAAATCGTCACGAATTGACTTAGAGCAAGGGTCAGCAAGCTTGTCTGTAAAGGGCCAAACA
GTAAATATTTTAGGGCTGGGGGCCATAAAATATGTTGCAACCACCCAATTCTGCCATTGTAGTGCAAAAGCAGCCATAGACAACACATAC
ATGAACGAACGTGGCTGTATTCCAATAAAACTTTATTTATGGACACTGAAATTGGAATTTCATATATTTTTCACATGTCACAAATACTCT
TGTTTTGACTTTTTTTCAACCATTTAAAAACTTAAAAACTATTCTTAATTCAGGGGCCATACAAAAACAGGTGGCAGGCTAGATTTGGCC
CAAGGACCTTAATTTGCCAACACAACTAAGAGAAGAGAACTGGGAACAAGGAGCACAAAGATCTGAAAACAGGAAAGGAAGTTTAGCCAT
ACATTTTATGGCCGAGAATTAGAAGCTTAGAATTAGAAGCTTTGGGGCATTTCAAGTGTAAATATGTCCTATAACATAAGAGTCATTAAA
ATTCAATTTAGTTCCTGTATTGTGTACCACAGTGCACTCCTCTTTAGGATTTTTTTACATATAGAAATAATATTGGGTTTTTTTTAAGGT
TATTGCCTATTCAGTTAATAGGGTTGCTTTAAAAAAGGTTATTGCTTAATCATAGATTAGATTACTCATTTTTGGTTTTCAAAATGAATT
TAGAATGACGTATAATTTAATATCTACTGAATTGCAATGTCTTAACAAGAAACCTAACAATTTTTTAAAGCAAAAGTAGATTGAGTTGGC
GTTTAAATTTATTTTGCAAGGTTTGTACTGACACTATACTTATATATTTATTATACATCGCTCTCTTGATATTGCCATGGATTAGAAGCA
TTAGTTCTCAGTACTTGAAGACAAACTTCTAAAAAGAAAATATATGCTCTGAACATCTGAAATGGGCTAGACTTTCAAGTAAAATTGCTT
CATTTCTCATTAACTGAAGAGCTATTGATCCAAGTCATACTTGCCATTTAATGTAAATTATTTTTAAACTTTGCTGTACAAAACCATTAA
GTGTAAAGGATTCTTCATATTCTTAGTATGAAGCAAATTATGAATTTTAAAAATGAAATATGTATTCCTCTAAAACCCAAACTTTTATCT
TTCCATTGGTATCTTTGAATTTTAAGACACTTTTCTTCAAATTACAAAACACTAAAACTCACTCCTAAACTTCACTTTGAGAAACTTTTT
TAACCAATTATAAAAATAAAACCATCCCCATGTGTTTCTTGCATATTCTAAAAACAGAAGTGTTAAAAATACACCACACAGGCTGGGCAG
AGTGGCTCACGCCTGTAACTCCAGCACTTTGGGAGGCCAAGATGGGCGGATCAGGACAGAGAATGAGGCCATCCTGGCCAACATGGTGAA
ACCCAATCTCTACTAAAAGTACAAAAATTAGCTGAGCGTGGTGGCACGTGCCTGTAATCCCAGCTACTCGGGAGGCTGAGGCAGGAGAAT
CACTTGAACCTGGGAGGTGGAGGCTGCAGTGAGCCAAGATCGCACCACCACGCTCCAGCCTGGTGACAGAGCGAGACTCCGTCTCAAAAA
AAAAAAAAAAAAAAAAAAAAAAAAAAAAAACACCATACAGCTTTCATGTCATTGAAAGTTCTTACTGGGTCAAAGCCTTAAGGCTAGAAC
TACCATTTTCTTGTCAACAGAATTCAGGCTATTCCAGTTTGATGTAATCTATACAGTAGTACAGTTTTAAGTCAAATATTCATTCTAACA
AATGCACAATGCTGCTCCATTTTAAAAATATTCCGGAAACACTTTATCAAGCCTCTATAAGTGAACATGCCAAACAGTTTGCCCTACCAC
GTGTTGAAAACTGAGTTGCTGGTCTAAGTGGCTAGAGGCCAAATGAAAACTGTGCAGAGTAACAAGATGAAAAGACTCGTCTCTTTAGGT
TTATCACATTTGATTCTGATGCTAAGCGCTGCCCCACTCCTCCTCCATGACCTTTAACACAGGTGTATGTTTTACAACATAAATCTGAGA
CTGAAGTTGAGACCAGGTTGTTTAGCAAGTGAGAGAATCCAGCCTACTGCCTAGGTTGCATCCCAATTTAGTTGTTTATCACATTTTGAG
GTGAAAGTACATACTTCATTGTATTTGAGTCTTTGGGATTACAGAAAGAACACATTGTTTCAAAATGTAAAGAGTTGGCTGGGCACAGTG
GCTCATGCCTGTAATCCCAACACTCTGGGAGGCTGAGGTGGGTGGATCACCTGAGGTCTGGAGTTCGAGGCCAACATGGTGAAACCCGTC
TCTACTAAAAATACAAAAATTAGCTGGGTACTAAAAATACAAAAATTAGTGGTGGTGGGCACCTGTAAATCCCAGCTATTGGGGAGGCTG
AGGCAGGAGAGAATTGCCTGAACTCAAGACGCAGAGGTTGCAGTGAGTGGAGACTGTGCCACTGCACTCCAGCCTGGGTACAAGAGTGAG
ACTCCATCTCAAAAAAAAAAAAAAAAAGTAAAGAGTCTAGTCTACTATTATACACAAATGGCCAGCACAATCTGATGTTGGCTGAAAATA
TTTAAGTTTTATTTAAAGCTTTCTGAATTAAACAGCTATATTATGCCAAGTGAAAGAAATTATCCTAAATAGCCACTATGACTATACCCA
TTACCATTTCACACTTTTTAGGCCACCAGAAATCTGGGTAGCAAACTCTTCTCATTAAAGTTGATGTGGACAAGAATCTAAATATGCAAG
TTGGGGTCATTACAAAATTTTAAGAAGCATCACTGAAAGTGAAGAGAAAGGAGCATGAATTCTGTCACTCTATTCAGTGATGCCAAATCT
GTAGGAATGATCCTATCTGGGTAGAAAGTGCCCTTTGAGGGGTAAAGCTTCTTTTCATGTCATCATTAGCAAGTAAAAGTTATTTACAAA
TTCTCCAGTTGGGAGTCAATATGAAGTCTAGACTCAACAAAAGTTGAGTTACAAGTGACTTGTTTTTAATCAAACTTGCTTTCTTTTATG
GGAGGCTTTTATGCCTCCCATCTCAATACCTCTGGAGACACTGGAAGCTCATTAATGAAAGTGGGCCCTCTATGATATGTATCAATTTAC
CTTTTGCTAACTACATCGTCCCCTTCCTTTCTTCTCTCCTCTTCCAATATCTCTATAGACTTCTGTCCTCTGCCCAGAGACCCACAGGCC
TTGCTTAATTCTGGAAAGTTATCAGGGCTTGCTTACTGGCCCAATAAAATTGAATTAACTCTAAAACACAAAACTCCACATCTATGCTCC
CATGCTAGTAAAGAAGAGTAGGATTTTCCTGGCTGGTGTCTTTGATCTTACATTGGCAGCCTGCAGGGAAAGTGCTCTCATGGTGAAAGT
CTCTGACCCCTTTTCAGTTGCTTATATATCAGCAGTGAGGCCAGAAAAGATATACCTGGGACCCCAAAAAAGTTAGAGAGAAAAGGGAGA
TTGTCTCTTATACAGAGTCTAGACTTGGGTCAATATTCCCCATGATCCATTGTTAATAATTTATGTGTTCTCTGCCATCCTTATGTAGCA
GCTTCCTAAAAGCAATCCTTGGCTGATGGCTATGGATTCTGACATAGGAATACCTGAAATGAGTCCCTTTGAAACACATACTGAGTCTCT
ATGATTACCAAGTTATTCTTTTTTTTTTTTTTTTTTTTGAGGCAAAGTCTCACTCTGTTGCCCAGCCTGGAGTGCAGTGGTACGATCTCG
ACTCACCACAACCTCCACCTCCCAGGTTCAAGTGATTCTCCTGCCTCAGCCTCCCAAGTAGCTGGGACTACAGGTGTGCGCCATGTCCGT
CTAATTTTTTTTATTTTCAGTAGAGACGGGGGTTTCACTATGTTGGTAAGGCTGGTCTCGAACTCCTGACCTCGTGATCCACCCGCCTCA
GCCTCCCAAAGTGCTGGGATTACAGGCGTGAGCCACCACACCTGGCCTACCTACTCTTATACATCTCTTAGATTCAAAACATACTATGCA
CAAGCCTGTCACCAAACAGATCTCTGAAACCTTCCCTATTGCAGATGACATAGGTCTCTAAACTTTTGACACAAGTAATTCTAACACTGA
ATTGGGTACTGTCGCATTTTTCAAAAGCGTTATGTGGATGATTTGACTCAGCATGGAAGACTGAGGTTGTCTTACACCCATTATTTCCCA
CCCCACTCTTAAGTGCCAGCATAGTGCTAAACACACAGTAGGTGCTCATTATTTGTCTAGTTAAAAAACAAATTAAGGCTGTAGCTTAAT
ATAGCCTCAGGATATGTGTGTGCCTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTTTAAACATAAGCTTACATATAAG
CGTATGTAAGTTAATGCACAAATATATTTCCTCAAATTCACATAGGATACTCAAATATAGATGTATAATTTTGTAGTCCCACTGTGATTC
TCCATATGTATAACAAGAAAATTAAAGGCATAATACAGCTGTGAAATAGCTGATGAGTTTCTATTTTAAGCTGATTTTTCACCAGAAGTA

>59956_59956_7_NPLOC4-PLCE1_NPLOC4_chr17_79577235_ENST00000374747_PLCE1_chr10_96081657_ENST00000371380_length(amino acids)=376AA_BP=188
LERRWRRRREAGAGAEAAAGSARPLGRQAAAARGSSPEAGAAAMAESIIIRVQSPDGVKRITATKRETAATFLKKVAKEFGFQNNGFSVY
INRNKTGEITASSNKSLNLLKIKHGDLLFLFPSSLAGPSSEMETSVPPGFKVFGAPNVVEDEIDQYLSKQDGKIYRSRDPQLCRHGPLGK
CVHCVPLENLEEKNIVQDDKEVILSSEEESFFVQVHDVSPEQPRTVIKAPRVSTAQDVIQQTLCKAKYSYSILSNPNPSDYVLLEEVVKD
TTNKKTTTPKSSQRVLLDQECVFQAQSKWKGAGKFILKLKEQVQASREDKKKGISFASELKKLTKSTKQPRGLTSPSQLLTSESIQTKEE

--------------------------------------------------------------
>59956_59956_8_NPLOC4-PLCE1_NPLOC4_chr17_79577235_ENST00000374747_PLCE1_chr10_96081657_ENST00000371385_length(transcript)=1581nt_BP=565nt
GCTGGAGCGGCGGTGGCGGCGGCGTAGGGAGGCCGGGGCCGGGGCTGAGGCCGCGGCCGGGTCTGCGAGGCCCTTGGGGCGGCAGGCGGC
GGCGGCCCGGGGCTCGAGCCCGGAGGCAGGAGCAGCCGCCATGGCCGAGAGCATCATAATTCGTGTCCAGTCCCCGGATGGAGTGAAGCG
GATCACAGCAACAAAGAGAGAAACAGCAGCAACATTTTTGAAAAAGGTTGCAAAGGAGTTTGGCTTCCAAAATAATGGCTTCTCGGTTTA
CATCAATAGAAACAAGACCGGAGAGATAACAGCCTCCTCCAACAAATCCCTCAACTTGCTAAAAATCAAGCATGGCGATTTGTTGTTCCT
GTTTCCCTCGAGCCTTGCTGGGCCCTCATCTGAAATGGAGACGTCAGTTCCACCGGGCTTCAAAGTCTTTGGCGCTCCCAACGTGGTGGA
GGATGAGATTGATCAGTACCTCAGCAAACAGGACGGGAAGATTTACAGAAGCCGAGACCCACAGCTATGCCGCCACGGCCCTTTGGGGAA
ATGCGTGCACTGCGTCCCTCTAGAGAACCTAGAAGAGAAAAACATTGTTCAAGATGACAAAGAGGTGATCTTGAGCTCAGAGGAGGAGAG
TTTCTTTGTCCAAGTGCATGATGTTTCTCCAGAGCAACCTCGAACAGTCATCAAAGCACCCCGCGTCAGCACTGCACAGGATGTCATTCA
GCAGACCTTATGCAAAGCCAAATATTCCTACAGCATCCTGAGCAACCCCAATCCAAGCGACTATGTGCTTTTGGAAGAGGTGGTGAAAGA
CACTACCAACAAGAAGACTACCACACCAAAGTCCTCTCAGCGGGTCCTTCTGGATCAGGAGTGTGTGTTTCAAGCCCAAAGCAAGTGGAA
AGGTGCAGGAAAATTCATCCTTAAGCTAAAGGAGCAGGTGCAGGCATCTCGAGAAGATAAAAAGAAAGGCATTTCTTTCGCAAGTGAACT
CAAGAAGCTCACCAAGTCAACTAAACAGCCCCGAGGACTTACATCACCTTCTCAGCTCTTGACCTCAGAAAGTATCCAAACCAAGGAGGA
GAAACCTGTGGGTGGCTTGTCCTCCAGTGACACAATGGATTACCGACAGTGACTAAGGGCAGCATGTTTAACCCAGGTGAAGATCTTTAA
GCAAGAAGTTAAAGAGTGAACATGGTGGAAAAAATATAATTATTTTCATCAGACTTAAACTGGAAATTGATGATTTCTGAACTGAAGCCT
TCACACATGTGAGATCCATGCTGAGGAGAAGCAAAATGGCACAGGGCTAGTTGCCACCAACCAATTTACTGATGAATGAAGCCCAGGGGA
CTGCCATTTTATAAATGTCAGCAGTTGGAAAAATCGTCACGAATTGACTTAGAGCAAGGGTCAGCAAGCTTGTCTGTAAAGGGCCAAACA
GTAAATATTTTAGGGCTGGGGGCCATAAAATATGTTGCAACCACCCAATTCTGCCATTGTAGTGCAAAAGCAGCCATAGACAACACATAC

>59956_59956_8_NPLOC4-PLCE1_NPLOC4_chr17_79577235_ENST00000374747_PLCE1_chr10_96081657_ENST00000371385_length(amino acids)=376AA_BP=188
LERRWRRRREAGAGAEAAAGSARPLGRQAAAARGSSPEAGAAAMAESIIIRVQSPDGVKRITATKRETAATFLKKVAKEFGFQNNGFSVY
INRNKTGEITASSNKSLNLLKIKHGDLLFLFPSSLAGPSSEMETSVPPGFKVFGAPNVVEDEIDQYLSKQDGKIYRSRDPQLCRHGPLGK
CVHCVPLENLEEKNIVQDDKEVILSSEEESFFVQVHDVSPEQPRTVIKAPRVSTAQDVIQQTLCKAKYSYSILSNPNPSDYVLLEEVVKD
TTNKKTTTPKSSQRVLLDQECVFQAQSKWKGAGKFILKLKEQVQASREDKKKGISFASELKKLTKSTKQPRGLTSPSQLLTSESIQTKEE

--------------------------------------------------------------

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Fusion Gene PPI Analysis for NPLOC4-PLCE1


check button Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in

ChiPPI page.


check button Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160)
HgeneHgene's interactorsTgeneTgene's interactors


check button - Retained PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenStill interaction with


check button - Lost PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


check button - Retained PPIs, but lost function due to frame-shift fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


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Related Drugs for NPLOC4-PLCE1


check button Drugs targeting genes involved in this fusion gene.
(DrugBank Version 5.1.8 2021-05-08)
PartnerGeneUniProtAccDrugBank IDDrug nameDrug activityDrug typeDrug status

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Related Diseases for NPLOC4-PLCE1


check button Diseases associated with fusion partners.
(DisGeNet 4.0)
PartnerGeneDisease IDDisease name# pubmedsSource