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Center for Computational Systems Medicine
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Fusion Gene Summary

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Fusion Gene ORF analysis

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Fusion Genomic Features

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Fusion Protein Features

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Fusion Gene Sequence

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Fusion Gene PPI analysis

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Related Drugs

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Related Diseases

Fusion gene:NPNT-PPA2 (FusionGDB2 ID:60002)

Fusion Gene Summary for NPNT-PPA2

check button Fusion gene summary
Fusion gene informationFusion gene name: NPNT-PPA2
Fusion gene ID: 60002
HgeneTgene
Gene symbol

NPNT

PPA2

Gene ID

255743

27068

Gene namenephronectininorganic pyrophosphatase 2
SynonymsEGFL6L|POEMHSPC124|SCFAI|SCFI|SID6-306
Cytomap

4q24

4q24

Type of geneprotein-codingprotein-coding
Descriptionnephronectinpreosteoblast EGF-like repeat protein with MAM domaininorganic pyrophosphatase 2, mitochondrialPPase 2pyrophosphatase (inorganic) 2pyrophosphatase SID6-306pyrophosphate phospho-hydrolase 2
Modification date2020031320200313
UniProtAcc

Q6UXI9

.
Ensembl transtripts involved in fusion geneENST00000513430, ENST00000305572, 
ENST00000379987, ENST00000427316, 
ENST00000453617, ENST00000506666, 
ENST00000514622, 		ENST00000341695, 
ENST00000348706, ENST00000432483, 
ENST00000509426, ENST00000310267, 
ENST00000354147, ENST00000357415, 
ENST00000380004, 
Fusion gene scores* DoF score6 X 4 X 5=12017 X 10 X 8=1360
# samples 718
** MAII scorelog2(7/120*10)=-0.777607578663552
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0		log2(18/1360*10)=-2.91753783980803
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0
Context

PubMed: NPNT [Title/Abstract] AND PPA2 [Title/Abstract] AND fusion [Title/Abstract]

Most frequent breakpointNPNT(106848585)-PPA2(106377902), # samples:1
Anticipated loss of major functional domain due to fusion event.
* DoF score (Degree of Frequency) = # partners X # break points X # cancer types
** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)

check button Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez
PartnerGeneGO IDGO termPubMed ID

check buttonFusion gene breakpoints across NPNT (5'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check buttonFusion gene breakpoints across PPA2 (3'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check button Fusion gene information from two resources (ChiTars 5.0 and ChimerDB 4.0)
* All genome coordinats were lifted-over on hg19.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
SourceDiseaseSampleHgeneHchrHbpHstrandTgeneTchrTbpTstrand
ChimerDB4Non-CancerERR315445NPNTchr4

106848585

+PPA2chr4

106377902

-


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Fusion Gene ORF analysis for NPNT-PPA2

check button Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
ORFHenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrand
3UTR-3CDSENST00000513430ENST00000341695NPNTchr4

106848585

+PPA2chr4

106377902

-
3UTR-3CDSENST00000513430ENST00000348706NPNTchr4

106848585

+PPA2chr4

106377902

-
3UTR-3CDSENST00000513430ENST00000432483NPNTchr4

106848585

+PPA2chr4

106377902

-
3UTR-5UTRENST00000513430ENST00000509426NPNTchr4

106848585

+PPA2chr4

106377902

-
3UTR-intronENST00000513430ENST00000310267NPNTchr4

106848585

+PPA2chr4

106377902

-
3UTR-intronENST00000513430ENST00000354147NPNTchr4

106848585

+PPA2chr4

106377902

-
3UTR-intronENST00000513430ENST00000357415NPNTchr4

106848585

+PPA2chr4

106377902

-
3UTR-intronENST00000513430ENST00000380004NPNTchr4

106848585

+PPA2chr4

106377902

-
5CDS-5UTRENST00000305572ENST00000509426NPNTchr4

106848585

+PPA2chr4

106377902

-
5CDS-5UTRENST00000379987ENST00000509426NPNTchr4

106848585

+PPA2chr4

106377902

-
5CDS-5UTRENST00000427316ENST00000509426NPNTchr4

106848585

+PPA2chr4

106377902

-
5CDS-5UTRENST00000453617ENST00000509426NPNTchr4

106848585

+PPA2chr4

106377902

-
5CDS-5UTRENST00000506666ENST00000509426NPNTchr4

106848585

+PPA2chr4

106377902

-
5CDS-5UTRENST00000514622ENST00000509426NPNTchr4

106848585

+PPA2chr4

106377902

-
5CDS-intronENST00000305572ENST00000310267NPNTchr4

106848585

+PPA2chr4

106377902

-
5CDS-intronENST00000305572ENST00000354147NPNTchr4

106848585

+PPA2chr4

106377902

-
5CDS-intronENST00000305572ENST00000357415NPNTchr4

106848585

+PPA2chr4

106377902

-
5CDS-intronENST00000305572ENST00000380004NPNTchr4

106848585

+PPA2chr4

106377902

-
5CDS-intronENST00000379987ENST00000310267NPNTchr4

106848585

+PPA2chr4

106377902

-
5CDS-intronENST00000379987ENST00000354147NPNTchr4

106848585

+PPA2chr4

106377902

-
5CDS-intronENST00000379987ENST00000357415NPNTchr4

106848585

+PPA2chr4

106377902

-
5CDS-intronENST00000379987ENST00000380004NPNTchr4

106848585

+PPA2chr4

106377902

-
5CDS-intronENST00000427316ENST00000310267NPNTchr4

106848585

+PPA2chr4

106377902

-
5CDS-intronENST00000427316ENST00000354147NPNTchr4

106848585

+PPA2chr4

106377902

-
5CDS-intronENST00000427316ENST00000357415NPNTchr4

106848585

+PPA2chr4

106377902

-
5CDS-intronENST00000427316ENST00000380004NPNTchr4

106848585

+PPA2chr4

106377902

-
5CDS-intronENST00000453617ENST00000310267NPNTchr4

106848585

+PPA2chr4

106377902

-
5CDS-intronENST00000453617ENST00000354147NPNTchr4

106848585

+PPA2chr4

106377902

-
5CDS-intronENST00000453617ENST00000357415NPNTchr4

106848585

+PPA2chr4

106377902

-
5CDS-intronENST00000453617ENST00000380004NPNTchr4

106848585

+PPA2chr4

106377902

-
5CDS-intronENST00000506666ENST00000310267NPNTchr4

106848585

+PPA2chr4

106377902

-
5CDS-intronENST00000506666ENST00000354147NPNTchr4

106848585

+PPA2chr4

106377902

-
5CDS-intronENST00000506666ENST00000357415NPNTchr4

106848585

+PPA2chr4

106377902

-
5CDS-intronENST00000506666ENST00000380004NPNTchr4

106848585

+PPA2chr4

106377902

-
5CDS-intronENST00000514622ENST00000310267NPNTchr4

106848585

+PPA2chr4

106377902

-
5CDS-intronENST00000514622ENST00000354147NPNTchr4

106848585

+PPA2chr4

106377902

-
5CDS-intronENST00000514622ENST00000357415NPNTchr4

106848585

+PPA2chr4

106377902

-
5CDS-intronENST00000514622ENST00000380004NPNTchr4

106848585

+PPA2chr4

106377902

-
In-frameENST00000305572ENST00000341695NPNTchr4

106848585

+PPA2chr4

106377902

-
In-frameENST00000305572ENST00000348706NPNTchr4

106848585

+PPA2chr4

106377902

-
In-frameENST00000305572ENST00000432483NPNTchr4

106848585

+PPA2chr4

106377902

-
In-frameENST00000379987ENST00000341695NPNTchr4

106848585

+PPA2chr4

106377902

-
In-frameENST00000379987ENST00000348706NPNTchr4

106848585

+PPA2chr4

106377902

-
In-frameENST00000379987ENST00000432483NPNTchr4

106848585

+PPA2chr4

106377902

-
In-frameENST00000427316ENST00000341695NPNTchr4

106848585

+PPA2chr4

106377902

-
In-frameENST00000427316ENST00000348706NPNTchr4

106848585

+PPA2chr4

106377902

-
In-frameENST00000427316ENST00000432483NPNTchr4

106848585

+PPA2chr4

106377902

-
In-frameENST00000453617ENST00000341695NPNTchr4

106848585

+PPA2chr4

106377902

-
In-frameENST00000453617ENST00000348706NPNTchr4

106848585

+PPA2chr4

106377902

-
In-frameENST00000453617ENST00000432483NPNTchr4

106848585

+PPA2chr4

106377902

-
In-frameENST00000506666ENST00000341695NPNTchr4

106848585

+PPA2chr4

106377902

-
In-frameENST00000506666ENST00000348706NPNTchr4

106848585

+PPA2chr4

106377902

-
In-frameENST00000506666ENST00000432483NPNTchr4

106848585

+PPA2chr4

106377902

-
In-frameENST00000514622ENST00000341695NPNTchr4

106848585

+PPA2chr4

106377902

-
In-frameENST00000514622ENST00000348706NPNTchr4

106848585

+PPA2chr4

106377902

-
In-frameENST00000514622ENST00000432483NPNTchr4

106848585

+PPA2chr4

106377902

-

check buttonORFfinder result based on the fusion transcript sequence of in-frame fusion genes.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandSeq length
(transcript)		BP loci
(transcript)		Predicted start
(transcript)		Predicted stop
(transcript)		Seq length
(amino acids)
ENST00000379987NPNTchr4106848585+ENST00000341695PPA2chr4106377902-1977481451328427
ENST00000379987NPNTchr4106848585+ENST00000348706PPA2chr4106377902-1724481451241398
ENST00000379987NPNTchr4106848585+ENST00000432483PPA2chr4106377902-1183481451022325
ENST00000453617NPNTchr4106848585+ENST00000341695PPA2chr4106377902-2025529421376444
ENST00000453617NPNTchr4106848585+ENST00000348706PPA2chr4106377902-1772529421289415
ENST00000453617NPNTchr4106848585+ENST00000432483PPA2chr4106377902-1231529421070342
ENST00000427316NPNTchr4106848585+ENST00000341695PPA2chr4106377902-1973477411324427
ENST00000427316NPNTchr4106848585+ENST00000348706PPA2chr4106377902-1720477411237398
ENST00000427316NPNTchr4106848585+ENST00000432483PPA2chr4106377902-1179477411018325
ENST00000514622NPNTchr4106848585+ENST00000341695PPA2chr4106377902-1973477411324427
ENST00000514622NPNTchr4106848585+ENST00000348706PPA2chr4106377902-1720477411237398
ENST00000514622NPNTchr4106848585+ENST00000432483PPA2chr4106377902-1179477411018325
ENST00000305572NPNTchr4106848585+ENST00000341695PPA2chr4106377902-1963467311314427
ENST00000305572NPNTchr4106848585+ENST00000348706PPA2chr4106377902-1710467311227398
ENST00000305572NPNTchr4106848585+ENST00000432483PPA2chr4106377902-1169467311008325
ENST00000506666NPNTchr4106848585+ENST00000341695PPA2chr4106377902-1921425131272419
ENST00000506666NPNTchr4106848585+ENST00000348706PPA2chr4106377902-1668425131185390
ENST00000506666NPNTchr4106848585+ENST00000432483PPA2chr4106377902-112742513966317

check buttonDeepORF prediction of the coding potential based on the fusion transcript sequence of in-frame fusion genes. DeepORF is a coding potential classifier based on convolutional neural network by comparing the real Ribo-seq data. If the no-coding score < 0.5 and coding score > 0.5, then the in-frame fusion transcript is predicted as being likely translated.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandNo-coding scoreCoding score
ENST00000379987ENST00000341695NPNTchr4106848585+PPA2chr4106377902-0.0005606740.9994393
ENST00000379987ENST00000348706NPNTchr4106848585+PPA2chr4106377902-0.000621010.9993789
ENST00000379987ENST00000432483NPNTchr4106848585+PPA2chr4106377902-0.0009808680.99901915
ENST00000453617ENST00000341695NPNTchr4106848585+PPA2chr4106377902-0.0007719830.999228
ENST00000453617ENST00000348706NPNTchr4106848585+PPA2chr4106377902-0.0009332540.99906677
ENST00000453617ENST00000432483NPNTchr4106848585+PPA2chr4106377902-0.0013025390.99869746
ENST00000427316ENST00000341695NPNTchr4106848585+PPA2chr4106377902-0.0005148570.99948514
ENST00000427316ENST00000348706NPNTchr4106848585+PPA2chr4106377902-0.0005629740.99943703
ENST00000427316ENST00000432483NPNTchr4106848585+PPA2chr4106377902-0.0008787530.99912125
ENST00000514622ENST00000341695NPNTchr4106848585+PPA2chr4106377902-0.0005148570.99948514
ENST00000514622ENST00000348706NPNTchr4106848585+PPA2chr4106377902-0.0005629740.99943703
ENST00000514622ENST00000432483NPNTchr4106848585+PPA2chr4106377902-0.0008787530.99912125
ENST00000305572ENST00000341695NPNTchr4106848585+PPA2chr4106377902-0.0005214050.99947864
ENST00000305572ENST00000348706NPNTchr4106848585+PPA2chr4106377902-0.0005683060.99943167
ENST00000305572ENST00000432483NPNTchr4106848585+PPA2chr4106377902-0.0009094140.99909055
ENST00000506666ENST00000341695NPNTchr4106848585+PPA2chr4106377902-0.0004252490.9995747
ENST00000506666ENST00000348706NPNTchr4106848585+PPA2chr4106377902-0.000493780.99950624
ENST00000506666ENST00000432483NPNTchr4106848585+PPA2chr4106377902-0.0007746470.9992254

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Fusion Genomic Features for NPNT-PPA2


check buttonFusionAI prediction of the potential fusion gene breakpoint based on the pre-mature RNA sequence context (+/- 5kb of individual partner genes, total 20kb length sequence). FusionAI is a fusion gene breakpoint classifier based on convolutional neural network by comparing the fusion positive and negative sequence context of ~ 20K fusion gene data. From here, we can have the relative potentency of the 20K genomic sequence how individual sequnce will be likely used as the gene fusion breakpoints.
HgeneHchrHbpHstrandTgeneTchrTbpTstrand1-pp (fusion gene breakpoint)

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions. We integrated a total of 44 different types of human genomic feature loci information across five big categories including virus integration sites, repeats, structural variants, chromatin states, and gene expression regulation. More details are in help page.
genomic feature

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions that are ovelapped with the top 1% feature importance score regions. More details are in help page.

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Fusion Protein Features for NPNT-PPA2


check button Four levels of functional features of fusion genes
Go to FGviewer search page for the most frequent breakpoint (https://ccsmweb.uth.edu/FGviewer/chr4:106848585/chr4:106377902)
- FGviewer provides the online visualization of the retention search of the protein functional features across DNA, RNA, protein, and pathological levels.
- How to search
1. Put your fusion gene symbol.
2. Press the tab key until there will be shown the breakpoint information filled.
4. Go down and press 'Search' tab twice.
4. Go down to have the hyperlink of the search result.
5. Click the hyperlink.
6. See the FGviewer result for your fusion gene.
FGviewer

check buttonMain function of each fusion partner protein. (from UniProt)
HgeneTgene
NPNT

Q6UXI9

.
FUNCTION: Functional ligand of integrin alpha-8/beta-1 in kidney development. Regulates the expression of GDNF with integrin alpha-8/beta-1 which is essential for kidney development. May also play a role in the development and function of various tissues, regulating cell adhesion, spreading and survival through the binding of several integrins (By similarity). {ECO:0000250}.FUNCTION: Transcriptional activator which is required for calcium-dependent dendritic growth and branching in cortical neurons. Recruits CREB-binding protein (CREBBP) to nuclear bodies. Component of the CREST-BRG1 complex, a multiprotein complex that regulates promoter activation by orchestrating a calcium-dependent release of a repressor complex and a recruitment of an activator complex. In resting neurons, transcription of the c-FOS promoter is inhibited by BRG1-dependent recruitment of a phospho-RB1-HDAC1 repressor complex. Upon calcium influx, RB1 is dephosphorylated by calcineurin, which leads to release of the repressor complex. At the same time, there is increased recruitment of CREBBP to the promoter by a CREST-dependent mechanism, which leads to transcriptional activation. The CREST-BRG1 complex also binds to the NR2B promoter, and activity-dependent induction of NR2B expression involves a release of HDAC1 and recruitment of CREBBP (By similarity). {ECO:0000250}.

check buttonRetention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at

download page


* Minus value of BPloci means that the break pointn is located before the CDS.
- In-frame and retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneNPNTchr4:106848585chr4:106377902ENST00000305572+31152_8788510.0DomainEGF-like 1
HgeneNPNTchr4:106848585chr4:106377902ENST00000379987+31252_8788566.0DomainEGF-like 1
HgeneNPNTchr4:106848585chr4:106377902ENST00000427316+31352_8788596.0DomainEGF-like 1
HgeneNPNTchr4:106848585chr4:106377902ENST00000453617+41352_87105583.0DomainEGF-like 1
HgeneNPNTchr4:106848585chr4:106377902ENST00000506666+31252_8788567.0DomainEGF-like 1
HgeneNPNTchr4:106848585chr4:106377902ENST00000514622+31152_8788537.0DomainEGF-like 1

- In-frame and not-retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneNPNTchr4:106848585chr4:106377902ENST00000305572+311296_36588510.0Compositional biasNote=Pro-rich
HgeneNPNTchr4:106848585chr4:106377902ENST00000379987+312296_36588566.0Compositional biasNote=Pro-rich
HgeneNPNTchr4:106848585chr4:106377902ENST00000427316+313296_36588596.0Compositional biasNote=Pro-rich
HgeneNPNTchr4:106848585chr4:106377902ENST00000453617+413296_365105583.0Compositional biasNote=Pro-rich
HgeneNPNTchr4:106848585chr4:106377902ENST00000506666+312296_36588567.0Compositional biasNote=Pro-rich
HgeneNPNTchr4:106848585chr4:106377902ENST00000514622+311296_36588537.0Compositional biasNote=Pro-rich
HgeneNPNTchr4:106848585chr4:106377902ENST00000305572+311132_16888510.0DomainEGF-like 3
HgeneNPNTchr4:106848585chr4:106377902ENST00000305572+311169_21388510.0DomainEGF-like 4%3B calcium-binding
HgeneNPNTchr4:106848585chr4:106377902ENST00000305572+311214_25488510.0DomainEGF-like 5%3B calcium-binding
HgeneNPNTchr4:106848585chr4:106377902ENST00000305572+311420_56388510.0DomainMAM
HgeneNPNTchr4:106848585chr4:106377902ENST00000305572+31189_12888510.0DomainEGF-like 2%3B calcium-binding
HgeneNPNTchr4:106848585chr4:106377902ENST00000379987+312132_16888566.0DomainEGF-like 3
HgeneNPNTchr4:106848585chr4:106377902ENST00000379987+312169_21388566.0DomainEGF-like 4%3B calcium-binding
HgeneNPNTchr4:106848585chr4:106377902ENST00000379987+312214_25488566.0DomainEGF-like 5%3B calcium-binding
HgeneNPNTchr4:106848585chr4:106377902ENST00000379987+312420_56388566.0DomainMAM
HgeneNPNTchr4:106848585chr4:106377902ENST00000379987+31289_12888566.0DomainEGF-like 2%3B calcium-binding
HgeneNPNTchr4:106848585chr4:106377902ENST00000427316+313132_16888596.0DomainEGF-like 3
HgeneNPNTchr4:106848585chr4:106377902ENST00000427316+313169_21388596.0DomainEGF-like 4%3B calcium-binding
HgeneNPNTchr4:106848585chr4:106377902ENST00000427316+313214_25488596.0DomainEGF-like 5%3B calcium-binding
HgeneNPNTchr4:106848585chr4:106377902ENST00000427316+313420_56388596.0DomainMAM
HgeneNPNTchr4:106848585chr4:106377902ENST00000427316+31389_12888596.0DomainEGF-like 2%3B calcium-binding
HgeneNPNTchr4:106848585chr4:106377902ENST00000453617+413132_168105583.0DomainEGF-like 3
HgeneNPNTchr4:106848585chr4:106377902ENST00000453617+413169_213105583.0DomainEGF-like 4%3B calcium-binding
HgeneNPNTchr4:106848585chr4:106377902ENST00000453617+413214_254105583.0DomainEGF-like 5%3B calcium-binding
HgeneNPNTchr4:106848585chr4:106377902ENST00000453617+413420_563105583.0DomainMAM
HgeneNPNTchr4:106848585chr4:106377902ENST00000453617+41389_128105583.0DomainEGF-like 2%3B calcium-binding
HgeneNPNTchr4:106848585chr4:106377902ENST00000506666+312132_16888567.0DomainEGF-like 3
HgeneNPNTchr4:106848585chr4:106377902ENST00000506666+312169_21388567.0DomainEGF-like 4%3B calcium-binding
HgeneNPNTchr4:106848585chr4:106377902ENST00000506666+312214_25488567.0DomainEGF-like 5%3B calcium-binding
HgeneNPNTchr4:106848585chr4:106377902ENST00000506666+312420_56388567.0DomainMAM
HgeneNPNTchr4:106848585chr4:106377902ENST00000506666+31289_12888567.0DomainEGF-like 2%3B calcium-binding
HgeneNPNTchr4:106848585chr4:106377902ENST00000514622+311132_16888537.0DomainEGF-like 3
HgeneNPNTchr4:106848585chr4:106377902ENST00000514622+311169_21388537.0DomainEGF-like 4%3B calcium-binding
HgeneNPNTchr4:106848585chr4:106377902ENST00000514622+311214_25488537.0DomainEGF-like 5%3B calcium-binding
HgeneNPNTchr4:106848585chr4:106377902ENST00000514622+311420_56388537.0DomainMAM
HgeneNPNTchr4:106848585chr4:106377902ENST00000514622+31189_12888537.0DomainEGF-like 2%3B calcium-binding


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Fusion Gene Sequence for NPNT-PPA2


check button For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. To have fusion amino acid sequence, we ran ORFfinder and chose the longest ORF among the all predicted ones.
>60002_60002_1_NPNT-PPA2_NPNT_chr4_106848585_ENST00000305572_PPA2_chr4_106377902_ENST00000341695_length(transcript)=1963nt_BP=467nt
GGGAGGGGGCTCCGGGCGCCGCGCAGCAGACCTGCTCCGGCCGCGCGCCTCGCCGCTGTCCTCCGGGAGCGGCAGCAGTAGCCCGGGCGG
CGAGGGCTGGGGGTTCCTCGAGACTCTCAGAGGGGCGCCTCCCATCGGCGCCCACCACCCCAACCTGTTCCTCGCGCGCCACTGCGCTGC
GCCCCAGGACCCGCTGCCCAACATGGATTTTCTCCTGGCGCTGGTGCTGGTATCCTCGCTCTACCTGCAGGCGGCCGCCGAGTTCGACGG
GAGGTGGCCCAGGCAAATAGTGTCATCGATTGGCCTATGTCGTTATGGTGGGAGGATTGACTGCTGCTGGGGCTGGGCTCGCCAGTCTTG
GGGACAGTGTCAGCCTGTGTGCCAACCACGATGCAAACATGGTGAATGTATCGGGCCAAACAAGTGCAAGTGTCATCCTGGTTATGCTGG
AAAAACCTGTAATCAAGAGAATGTAACTGGTCACTACATTTCCCCCTTTCATGATATTCCTCTGAAGGTGAACTCTAAAGAGGAAAATGG
CATTCCTATGAAGAAAGCACGAAATGATGAATATGAGAATCTGTTTAATATGATTGTAGAAATACCTCGGTGGACAAATGCTAAAATGGA
GATTGCCACCAAGGAGCCAATGAATCCCATTAAACAATATGTAAAGGATGGAAAGCTACGCTATGTGGCGAATATCTTCCCTTACAAGGG
TTATATATGGAATTATGGTACCCTCCCTCAGACTTGGGAAGATCCCCATGAAAAAGATAAGAGCACGAACTGCTTTGGAGATAATGATCC
TATTGATGTTTGCGAAATAGGCTCAAAGATTCTTTCTTGTGGAGAAGTTATTCATGTGAAGATCCTTGGAATTTTGGCTCTTATTGATGA
AGGTGAAACAGATTGGAAATTAATTGCTATCAATGCGAATGATCCTGAAGCCTCAAAGTTTCATGATATTGATGATGTTAAGAAGTTCAA
ACCGGGTTACCTGGAAGCTACTCTTAATTGGTTTAGATTATATAAGGTACCAGATGGAAAACCAGAAAACCAGTTTGCTTTTAATGGAGA
ATTCAAAAACAAGGCTTTTGCTCTTGAAGTTATTAAATCCACTCATCAATGTTGGAAAGCATTGCTTATGAAGAAGTGTAATGGAGGAGC
TATAAATTGCACAAACGTGCAGATATCTGATAGCCCTTTCCGTTGCACTCAAGAGGAAGCAAGATCATTAGTTGAATCGGTATCATCTTC
ACCAAATAAAGAAAGTAATGAAGAAGAGCAAGTGTGGCACTTCCTTGGCAAGTGATTGAAACATCTGAAATTCTGCTGTCAAGATTCCCA
TCTCTAAGGACTCCAAGTGCTAGAGACAAGGGGGTCTATGAGCATTTACTGACTTCCTGTTAAAACTTCATTTTTTCAAACTTTTTGAGC
TATGCAATATATAAATAAACAGTAAGAATTTTAAATTACTCTCCTTTGGACATTTATTGATATAAAAAGAAGATTTTGGCCAGGCACGGT
GGCTCATGCCTGTAATTTCAGCACTTTGGGAGGCCGAGGTGGGCAGATCACAAGGTCAGGAGTTCAAGACCAGCCTGGCCAGTATGTTGA
AACCCCATCTCTATTAAAAATACAAAAATTAGCCAGGCGTGGTGGTGCATGCCTGTAGACCCAGCTACTCAGGAGGCTGAGGCAGAAGAA
CTGCTTGAGCCCAGGAGGCAGAGGTTGCAGTGAGCAGAGATTGTGCCACTGCACTCCAGCCTAGGCGACAGAGAGAGACTCCGTCTCAAA
AAAAAAAAAAAGATTTTGTTTCATTTCATAGCACAAATTTAGAGGCATTGAGTTGACCATTTCTAGTTTCTATACCTGAAGGAACCCATT

>60002_60002_1_NPNT-PPA2_NPNT_chr4_106848585_ENST00000305572_PPA2_chr4_106377902_ENST00000341695_length(amino acids)=427AA_BP=145
MLRPRASPLSSGSGSSSPGGEGWGFLETLRGAPPIGAHHPNLFLARHCAAPQDPLPNMDFLLALVLVSSLYLQAAAEFDGRWPRQIVSSI
GLCRYGGRIDCCWGWARQSWGQCQPVCQPRCKHGECIGPNKCKCHPGYAGKTCNQENVTGHYISPFHDIPLKVNSKEENGIPMKKARNDE
YENLFNMIVEIPRWTNAKMEIATKEPMNPIKQYVKDGKLRYVANIFPYKGYIWNYGTLPQTWEDPHEKDKSTNCFGDNDPIDVCEIGSKI
LSCGEVIHVKILGILALIDEGETDWKLIAINANDPEASKFHDIDDVKKFKPGYLEATLNWFRLYKVPDGKPENQFAFNGEFKNKAFALEV

--------------------------------------------------------------
>60002_60002_2_NPNT-PPA2_NPNT_chr4_106848585_ENST00000305572_PPA2_chr4_106377902_ENST00000348706_length(transcript)=1710nt_BP=467nt
GGGAGGGGGCTCCGGGCGCCGCGCAGCAGACCTGCTCCGGCCGCGCGCCTCGCCGCTGTCCTCCGGGAGCGGCAGCAGTAGCCCGGGCGG
CGAGGGCTGGGGGTTCCTCGAGACTCTCAGAGGGGCGCCTCCCATCGGCGCCCACCACCCCAACCTGTTCCTCGCGCGCCACTGCGCTGC
GCCCCAGGACCCGCTGCCCAACATGGATTTTCTCCTGGCGCTGGTGCTGGTATCCTCGCTCTACCTGCAGGCGGCCGCCGAGTTCGACGG
GAGGTGGCCCAGGCAAATAGTGTCATCGATTGGCCTATGTCGTTATGGTGGGAGGATTGACTGCTGCTGGGGCTGGGCTCGCCAGTCTTG
GGGACAGTGTCAGCCTGTGTGCCAACCACGATGCAAACATGGTGAATGTATCGGGCCAAACAAGTGCAAGTGTCATCCTGGTTATGCTGG
AAAAACCTGTAATCAAGAGAATGTAACTGGTCACTACATTTCCCCCTTTCATGATATTCCTCTGAAGGTGAACTCTAAAGAGGAAAATGG
CATTCCTATGAAGAAAGCACGAAATGATGAATATGAGAATCTGTTTAATATGATTGTAGAAATACCTCGGTGGACAAATGCTAAAATGGA
GATTGCCACCAAGGAGCCAATGAATCCCATTAAACAATATGTAAAGGATGGAAAGCTACGCTATGTGGCGAATATCTTCCCTTACAAGGG
TTATATATGGAATTATGGTACCCTCCCTCAGATTCTTTCTTGTGGAGAAGTTATTCATGTGAAGATCCTTGGAATTTTGGCTCTTATTGA
TGAAGGTGAAACAGATTGGAAATTAATTGCTATCAATGCGAATGATCCTGAAGCCTCAAAGTTTCATGATATTGATGATGTTAAGAAGTT
CAAACCGGGTTACCTGGAAGCTACTCTTAATTGGTTTAGATTATATAAGGTACCAGATGGAAAACCAGAAAACCAGTTTGCTTTTAATGG
AGAATTCAAAAACAAGGCTTTTGCTCTTGAAGTTATTAAATCCACTCATCAATGTTGGAAAGCATTGCTTATGAAGAAGTGTAATGGAGG
AGCTATAAATTGCACAAACGTGCAGATATCTGATAGCCCTTTCCGTTGCACTCAAGAGGAAGCAAGATCATTAGTTGAATCGGTATCATC
TTCACCAAATAAAGAAAGTAATGAAGAAGAGCAAGTGTGGCACTTCCTTGGCAAGTGATTGAAACATCTGAAATTCTGCTGTCAAGATTC
CCATCTCTAAGGACTCCAAGTGCTAGAGACAAGGGGGTCTATGAGCATTTACTGACTTCCTGTTAAAACTTCATTTTTTCAAACTTTTTG
AGCTATGCAATATATAAATAAACAGTAAGAATTTTAAATTACTCTCCTTTGGACATTTATTGATATAAAAAGAAGATTTTGGCCAGGCAC
GGTGGCTCATGCCTGTAATTTCAGCACTTTGGGAGGCCGAGGTGGGCAGATCACAAGGTCAGGAGTTCAAGACCAGCCTGGCCAGTATGT
TGAAACCCCATCTCTATTAAAAATACAAAAATTAGCCAGGCGTGGTGGTGCATGCCTGTAGACCCAGCTACTCAGGAGGCTGAGGCAGAA
GAACTGCTTGAGCCCAGGAGGCAGAGGTTGCAGTGAGCAGAGATTGTGCCACTGCACTCCAGCCTAGGCGACAGAGAGAGACTCCGTCTC

>60002_60002_2_NPNT-PPA2_NPNT_chr4_106848585_ENST00000305572_PPA2_chr4_106377902_ENST00000348706_length(amino acids)=398AA_BP=145
MLRPRASPLSSGSGSSSPGGEGWGFLETLRGAPPIGAHHPNLFLARHCAAPQDPLPNMDFLLALVLVSSLYLQAAAEFDGRWPRQIVSSI
GLCRYGGRIDCCWGWARQSWGQCQPVCQPRCKHGECIGPNKCKCHPGYAGKTCNQENVTGHYISPFHDIPLKVNSKEENGIPMKKARNDE
YENLFNMIVEIPRWTNAKMEIATKEPMNPIKQYVKDGKLRYVANIFPYKGYIWNYGTLPQILSCGEVIHVKILGILALIDEGETDWKLIA
INANDPEASKFHDIDDVKKFKPGYLEATLNWFRLYKVPDGKPENQFAFNGEFKNKAFALEVIKSTHQCWKALLMKKCNGGAINCTNVQIS

--------------------------------------------------------------
>60002_60002_3_NPNT-PPA2_NPNT_chr4_106848585_ENST00000305572_PPA2_chr4_106377902_ENST00000432483_length(transcript)=1169nt_BP=467nt
GGGAGGGGGCTCCGGGCGCCGCGCAGCAGACCTGCTCCGGCCGCGCGCCTCGCCGCTGTCCTCCGGGAGCGGCAGCAGTAGCCCGGGCGG
CGAGGGCTGGGGGTTCCTCGAGACTCTCAGAGGGGCGCCTCCCATCGGCGCCCACCACCCCAACCTGTTCCTCGCGCGCCACTGCGCTGC
GCCCCAGGACCCGCTGCCCAACATGGATTTTCTCCTGGCGCTGGTGCTGGTATCCTCGCTCTACCTGCAGGCGGCCGCCGAGTTCGACGG
GAGGTGGCCCAGGCAAATAGTGTCATCGATTGGCCTATGTCGTTATGGTGGGAGGATTGACTGCTGCTGGGGCTGGGCTCGCCAGTCTTG
GGGACAGTGTCAGCCTGTGTGCCAACCACGATGCAAACATGGTGAATGTATCGGGCCAAACAAGTGCAAGTGTCATCCTGGTTATGCTGG
AAAAACCTGTAATCAAGAGAATGTAACTGGTCACTACATTTCCCCCTTTCATGATATTCCTCTGAAGGTGAACTCTAAAGAGATTCTTTC
TTGTGGAGAAGTTATTCATGTGAAGATCCTTGGAATTTTGGCTCTTATTGATGAAGGTGAAACAGATTGGAAATTAATTGCTATCAATGC
GAATGATCCTGAAGCCTCAAAGTTTCATGATATTGATGATGTTAAGAAGTTCAAACCGGGTTACCTGGAAGCTACTCTTAATTGGTTTAG
ATTATATAAGGTACCAGATGGAAAACCAGAAAACCAGTTTGCTTTTAATGGAGAATTCAAAAACAAGGCTTTTGCTCTTGAAGTTATTAA
ATCCACTCATCAATGTTGGAAAGCATTGCTTATGAAGAAGTGTAATGGAGGAGCTATAAATTGCACAAACGTGCAGATATCTGATAGCCC
TTTCCGTTGCACTCAAGAGGAAGCAAGATCATTAGTTGAATCGGTATCATCTTCACCAAATAAAGAAAGTAATGAAGAAGAGCAAGTGTG
GCACTTCCTTGGCAAGTGATTGAAACATCTGAAATTCTGCTGTCAAGATTCCCATCTCTAAGGACTCCAAGTGCTAGAGACAAGGGGGTC

>60002_60002_3_NPNT-PPA2_NPNT_chr4_106848585_ENST00000305572_PPA2_chr4_106377902_ENST00000432483_length(amino acids)=325AA_BP=145
MLRPRASPLSSGSGSSSPGGEGWGFLETLRGAPPIGAHHPNLFLARHCAAPQDPLPNMDFLLALVLVSSLYLQAAAEFDGRWPRQIVSSI
GLCRYGGRIDCCWGWARQSWGQCQPVCQPRCKHGECIGPNKCKCHPGYAGKTCNQENVTGHYISPFHDIPLKVNSKEILSCGEVIHVKIL
GILALIDEGETDWKLIAINANDPEASKFHDIDDVKKFKPGYLEATLNWFRLYKVPDGKPENQFAFNGEFKNKAFALEVIKSTHQCWKALL

--------------------------------------------------------------
>60002_60002_4_NPNT-PPA2_NPNT_chr4_106848585_ENST00000379987_PPA2_chr4_106377902_ENST00000341695_length(transcript)=1977nt_BP=481nt
AGCTAGAAGGGAGCGGGAGGGGGCTCCGGGCGCCGCGCAGCAGACCTGCTCCGGCCGCGCGCCTCGCCGCTGTCCTCCGGGAGCGGCAGC
AGTAGCCCGGGCGGCGAGGGCTGGGGGTTCCTCGAGACTCTCAGAGGGGCGCCTCCCATCGGCGCCCACCACCCCAACCTGTTCCTCGCG
CGCCACTGCGCTGCGCCCCAGGACCCGCTGCCCAACATGGATTTTCTCCTGGCGCTGGTGCTGGTATCCTCGCTCTACCTGCAGGCGGCC
GCCGAGTTCGACGGGAGGTGGCCCAGGCAAATAGTGTCATCGATTGGCCTATGTCGTTATGGTGGGAGGATTGACTGCTGCTGGGGCTGG
GCTCGCCAGTCTTGGGGACAGTGTCAGCCTGTGTGCCAACCACGATGCAAACATGGTGAATGTATCGGGCCAAACAAGTGCAAGTGTCAT
CCTGGTTATGCTGGAAAAACCTGTAATCAAGAGAATGTAACTGGTCACTACATTTCCCCCTTTCATGATATTCCTCTGAAGGTGAACTCT
AAAGAGGAAAATGGCATTCCTATGAAGAAAGCACGAAATGATGAATATGAGAATCTGTTTAATATGATTGTAGAAATACCTCGGTGGACA
AATGCTAAAATGGAGATTGCCACCAAGGAGCCAATGAATCCCATTAAACAATATGTAAAGGATGGAAAGCTACGCTATGTGGCGAATATC
TTCCCTTACAAGGGTTATATATGGAATTATGGTACCCTCCCTCAGACTTGGGAAGATCCCCATGAAAAAGATAAGAGCACGAACTGCTTT
GGAGATAATGATCCTATTGATGTTTGCGAAATAGGCTCAAAGATTCTTTCTTGTGGAGAAGTTATTCATGTGAAGATCCTTGGAATTTTG
GCTCTTATTGATGAAGGTGAAACAGATTGGAAATTAATTGCTATCAATGCGAATGATCCTGAAGCCTCAAAGTTTCATGATATTGATGAT
GTTAAGAAGTTCAAACCGGGTTACCTGGAAGCTACTCTTAATTGGTTTAGATTATATAAGGTACCAGATGGAAAACCAGAAAACCAGTTT
GCTTTTAATGGAGAATTCAAAAACAAGGCTTTTGCTCTTGAAGTTATTAAATCCACTCATCAATGTTGGAAAGCATTGCTTATGAAGAAG
TGTAATGGAGGAGCTATAAATTGCACAAACGTGCAGATATCTGATAGCCCTTTCCGTTGCACTCAAGAGGAAGCAAGATCATTAGTTGAA
TCGGTATCATCTTCACCAAATAAAGAAAGTAATGAAGAAGAGCAAGTGTGGCACTTCCTTGGCAAGTGATTGAAACATCTGAAATTCTGC
TGTCAAGATTCCCATCTCTAAGGACTCCAAGTGCTAGAGACAAGGGGGTCTATGAGCATTTACTGACTTCCTGTTAAAACTTCATTTTTT
CAAACTTTTTGAGCTATGCAATATATAAATAAACAGTAAGAATTTTAAATTACTCTCCTTTGGACATTTATTGATATAAAAAGAAGATTT
TGGCCAGGCACGGTGGCTCATGCCTGTAATTTCAGCACTTTGGGAGGCCGAGGTGGGCAGATCACAAGGTCAGGAGTTCAAGACCAGCCT
GGCCAGTATGTTGAAACCCCATCTCTATTAAAAATACAAAAATTAGCCAGGCGTGGTGGTGCATGCCTGTAGACCCAGCTACTCAGGAGG
CTGAGGCAGAAGAACTGCTTGAGCCCAGGAGGCAGAGGTTGCAGTGAGCAGAGATTGTGCCACTGCACTCCAGCCTAGGCGACAGAGAGA
GACTCCGTCTCAAAAAAAAAAAAAAGATTTTGTTTCATTTCATAGCACAAATTTAGAGGCATTGAGTTGACCATTTCTAGTTTCTATACC

>60002_60002_4_NPNT-PPA2_NPNT_chr4_106848585_ENST00000379987_PPA2_chr4_106377902_ENST00000341695_length(amino acids)=427AA_BP=145
MLRPRASPLSSGSGSSSPGGEGWGFLETLRGAPPIGAHHPNLFLARHCAAPQDPLPNMDFLLALVLVSSLYLQAAAEFDGRWPRQIVSSI
GLCRYGGRIDCCWGWARQSWGQCQPVCQPRCKHGECIGPNKCKCHPGYAGKTCNQENVTGHYISPFHDIPLKVNSKEENGIPMKKARNDE
YENLFNMIVEIPRWTNAKMEIATKEPMNPIKQYVKDGKLRYVANIFPYKGYIWNYGTLPQTWEDPHEKDKSTNCFGDNDPIDVCEIGSKI
LSCGEVIHVKILGILALIDEGETDWKLIAINANDPEASKFHDIDDVKKFKPGYLEATLNWFRLYKVPDGKPENQFAFNGEFKNKAFALEV

--------------------------------------------------------------
>60002_60002_5_NPNT-PPA2_NPNT_chr4_106848585_ENST00000379987_PPA2_chr4_106377902_ENST00000348706_length(transcript)=1724nt_BP=481nt
AGCTAGAAGGGAGCGGGAGGGGGCTCCGGGCGCCGCGCAGCAGACCTGCTCCGGCCGCGCGCCTCGCCGCTGTCCTCCGGGAGCGGCAGC
AGTAGCCCGGGCGGCGAGGGCTGGGGGTTCCTCGAGACTCTCAGAGGGGCGCCTCCCATCGGCGCCCACCACCCCAACCTGTTCCTCGCG
CGCCACTGCGCTGCGCCCCAGGACCCGCTGCCCAACATGGATTTTCTCCTGGCGCTGGTGCTGGTATCCTCGCTCTACCTGCAGGCGGCC
GCCGAGTTCGACGGGAGGTGGCCCAGGCAAATAGTGTCATCGATTGGCCTATGTCGTTATGGTGGGAGGATTGACTGCTGCTGGGGCTGG
GCTCGCCAGTCTTGGGGACAGTGTCAGCCTGTGTGCCAACCACGATGCAAACATGGTGAATGTATCGGGCCAAACAAGTGCAAGTGTCAT
CCTGGTTATGCTGGAAAAACCTGTAATCAAGAGAATGTAACTGGTCACTACATTTCCCCCTTTCATGATATTCCTCTGAAGGTGAACTCT
AAAGAGGAAAATGGCATTCCTATGAAGAAAGCACGAAATGATGAATATGAGAATCTGTTTAATATGATTGTAGAAATACCTCGGTGGACA
AATGCTAAAATGGAGATTGCCACCAAGGAGCCAATGAATCCCATTAAACAATATGTAAAGGATGGAAAGCTACGCTATGTGGCGAATATC
TTCCCTTACAAGGGTTATATATGGAATTATGGTACCCTCCCTCAGATTCTTTCTTGTGGAGAAGTTATTCATGTGAAGATCCTTGGAATT
TTGGCTCTTATTGATGAAGGTGAAACAGATTGGAAATTAATTGCTATCAATGCGAATGATCCTGAAGCCTCAAAGTTTCATGATATTGAT
GATGTTAAGAAGTTCAAACCGGGTTACCTGGAAGCTACTCTTAATTGGTTTAGATTATATAAGGTACCAGATGGAAAACCAGAAAACCAG
TTTGCTTTTAATGGAGAATTCAAAAACAAGGCTTTTGCTCTTGAAGTTATTAAATCCACTCATCAATGTTGGAAAGCATTGCTTATGAAG
AAGTGTAATGGAGGAGCTATAAATTGCACAAACGTGCAGATATCTGATAGCCCTTTCCGTTGCACTCAAGAGGAAGCAAGATCATTAGTT
GAATCGGTATCATCTTCACCAAATAAAGAAAGTAATGAAGAAGAGCAAGTGTGGCACTTCCTTGGCAAGTGATTGAAACATCTGAAATTC
TGCTGTCAAGATTCCCATCTCTAAGGACTCCAAGTGCTAGAGACAAGGGGGTCTATGAGCATTTACTGACTTCCTGTTAAAACTTCATTT
TTTCAAACTTTTTGAGCTATGCAATATATAAATAAACAGTAAGAATTTTAAATTACTCTCCTTTGGACATTTATTGATATAAAAAGAAGA
TTTTGGCCAGGCACGGTGGCTCATGCCTGTAATTTCAGCACTTTGGGAGGCCGAGGTGGGCAGATCACAAGGTCAGGAGTTCAAGACCAG
CCTGGCCAGTATGTTGAAACCCCATCTCTATTAAAAATACAAAAATTAGCCAGGCGTGGTGGTGCATGCCTGTAGACCCAGCTACTCAGG
AGGCTGAGGCAGAAGAACTGCTTGAGCCCAGGAGGCAGAGGTTGCAGTGAGCAGAGATTGTGCCACTGCACTCCAGCCTAGGCGACAGAG

>60002_60002_5_NPNT-PPA2_NPNT_chr4_106848585_ENST00000379987_PPA2_chr4_106377902_ENST00000348706_length(amino acids)=398AA_BP=145
MLRPRASPLSSGSGSSSPGGEGWGFLETLRGAPPIGAHHPNLFLARHCAAPQDPLPNMDFLLALVLVSSLYLQAAAEFDGRWPRQIVSSI
GLCRYGGRIDCCWGWARQSWGQCQPVCQPRCKHGECIGPNKCKCHPGYAGKTCNQENVTGHYISPFHDIPLKVNSKEENGIPMKKARNDE
YENLFNMIVEIPRWTNAKMEIATKEPMNPIKQYVKDGKLRYVANIFPYKGYIWNYGTLPQILSCGEVIHVKILGILALIDEGETDWKLIA
INANDPEASKFHDIDDVKKFKPGYLEATLNWFRLYKVPDGKPENQFAFNGEFKNKAFALEVIKSTHQCWKALLMKKCNGGAINCTNVQIS

--------------------------------------------------------------
>60002_60002_6_NPNT-PPA2_NPNT_chr4_106848585_ENST00000379987_PPA2_chr4_106377902_ENST00000432483_length(transcript)=1183nt_BP=481nt
AGCTAGAAGGGAGCGGGAGGGGGCTCCGGGCGCCGCGCAGCAGACCTGCTCCGGCCGCGCGCCTCGCCGCTGTCCTCCGGGAGCGGCAGC
AGTAGCCCGGGCGGCGAGGGCTGGGGGTTCCTCGAGACTCTCAGAGGGGCGCCTCCCATCGGCGCCCACCACCCCAACCTGTTCCTCGCG
CGCCACTGCGCTGCGCCCCAGGACCCGCTGCCCAACATGGATTTTCTCCTGGCGCTGGTGCTGGTATCCTCGCTCTACCTGCAGGCGGCC
GCCGAGTTCGACGGGAGGTGGCCCAGGCAAATAGTGTCATCGATTGGCCTATGTCGTTATGGTGGGAGGATTGACTGCTGCTGGGGCTGG
GCTCGCCAGTCTTGGGGACAGTGTCAGCCTGTGTGCCAACCACGATGCAAACATGGTGAATGTATCGGGCCAAACAAGTGCAAGTGTCAT
CCTGGTTATGCTGGAAAAACCTGTAATCAAGAGAATGTAACTGGTCACTACATTTCCCCCTTTCATGATATTCCTCTGAAGGTGAACTCT
AAAGAGATTCTTTCTTGTGGAGAAGTTATTCATGTGAAGATCCTTGGAATTTTGGCTCTTATTGATGAAGGTGAAACAGATTGGAAATTA
ATTGCTATCAATGCGAATGATCCTGAAGCCTCAAAGTTTCATGATATTGATGATGTTAAGAAGTTCAAACCGGGTTACCTGGAAGCTACT
CTTAATTGGTTTAGATTATATAAGGTACCAGATGGAAAACCAGAAAACCAGTTTGCTTTTAATGGAGAATTCAAAAACAAGGCTTTTGCT
CTTGAAGTTATTAAATCCACTCATCAATGTTGGAAAGCATTGCTTATGAAGAAGTGTAATGGAGGAGCTATAAATTGCACAAACGTGCAG
ATATCTGATAGCCCTTTCCGTTGCACTCAAGAGGAAGCAAGATCATTAGTTGAATCGGTATCATCTTCACCAAATAAAGAAAGTAATGAA
GAAGAGCAAGTGTGGCACTTCCTTGGCAAGTGATTGAAACATCTGAAATTCTGCTGTCAAGATTCCCATCTCTAAGGACTCCAAGTGCTA
GAGACAAGGGGGTCTATGAGCATTTACTGACTTCCTGTTAAAACTTCATTTTTTCAAACTTTTTGAGCTATGCAATATATAAATAAACAG

>60002_60002_6_NPNT-PPA2_NPNT_chr4_106848585_ENST00000379987_PPA2_chr4_106377902_ENST00000432483_length(amino acids)=325AA_BP=145
MLRPRASPLSSGSGSSSPGGEGWGFLETLRGAPPIGAHHPNLFLARHCAAPQDPLPNMDFLLALVLVSSLYLQAAAEFDGRWPRQIVSSI
GLCRYGGRIDCCWGWARQSWGQCQPVCQPRCKHGECIGPNKCKCHPGYAGKTCNQENVTGHYISPFHDIPLKVNSKEILSCGEVIHVKIL
GILALIDEGETDWKLIAINANDPEASKFHDIDDVKKFKPGYLEATLNWFRLYKVPDGKPENQFAFNGEFKNKAFALEVIKSTHQCWKALL

--------------------------------------------------------------
>60002_60002_7_NPNT-PPA2_NPNT_chr4_106848585_ENST00000427316_PPA2_chr4_106377902_ENST00000341695_length(transcript)=1973nt_BP=477nt
AGAAGGGAGCGGGAGGGGGCTCCGGGCGCCGCGCAGCAGACCTGCTCCGGCCGCGCGCCTCGCCGCTGTCCTCCGGGAGCGGCAGCAGTA
GCCCGGGCGGCGAGGGCTGGGGGTTCCTCGAGACTCTCAGAGGGGCGCCTCCCATCGGCGCCCACCACCCCAACCTGTTCCTCGCGCGCC
ACTGCGCTGCGCCCCAGGACCCGCTGCCCAACATGGATTTTCTCCTGGCGCTGGTGCTGGTATCCTCGCTCTACCTGCAGGCGGCCGCCG
AGTTCGACGGGAGGTGGCCCAGGCAAATAGTGTCATCGATTGGCCTATGTCGTTATGGTGGGAGGATTGACTGCTGCTGGGGCTGGGCTC
GCCAGTCTTGGGGACAGTGTCAGCCTGTGTGCCAACCACGATGCAAACATGGTGAATGTATCGGGCCAAACAAGTGCAAGTGTCATCCTG
GTTATGCTGGAAAAACCTGTAATCAAGAGAATGTAACTGGTCACTACATTTCCCCCTTTCATGATATTCCTCTGAAGGTGAACTCTAAAG
AGGAAAATGGCATTCCTATGAAGAAAGCACGAAATGATGAATATGAGAATCTGTTTAATATGATTGTAGAAATACCTCGGTGGACAAATG
CTAAAATGGAGATTGCCACCAAGGAGCCAATGAATCCCATTAAACAATATGTAAAGGATGGAAAGCTACGCTATGTGGCGAATATCTTCC
CTTACAAGGGTTATATATGGAATTATGGTACCCTCCCTCAGACTTGGGAAGATCCCCATGAAAAAGATAAGAGCACGAACTGCTTTGGAG
ATAATGATCCTATTGATGTTTGCGAAATAGGCTCAAAGATTCTTTCTTGTGGAGAAGTTATTCATGTGAAGATCCTTGGAATTTTGGCTC
TTATTGATGAAGGTGAAACAGATTGGAAATTAATTGCTATCAATGCGAATGATCCTGAAGCCTCAAAGTTTCATGATATTGATGATGTTA
AGAAGTTCAAACCGGGTTACCTGGAAGCTACTCTTAATTGGTTTAGATTATATAAGGTACCAGATGGAAAACCAGAAAACCAGTTTGCTT
TTAATGGAGAATTCAAAAACAAGGCTTTTGCTCTTGAAGTTATTAAATCCACTCATCAATGTTGGAAAGCATTGCTTATGAAGAAGTGTA
ATGGAGGAGCTATAAATTGCACAAACGTGCAGATATCTGATAGCCCTTTCCGTTGCACTCAAGAGGAAGCAAGATCATTAGTTGAATCGG
TATCATCTTCACCAAATAAAGAAAGTAATGAAGAAGAGCAAGTGTGGCACTTCCTTGGCAAGTGATTGAAACATCTGAAATTCTGCTGTC
AAGATTCCCATCTCTAAGGACTCCAAGTGCTAGAGACAAGGGGGTCTATGAGCATTTACTGACTTCCTGTTAAAACTTCATTTTTTCAAA
CTTTTTGAGCTATGCAATATATAAATAAACAGTAAGAATTTTAAATTACTCTCCTTTGGACATTTATTGATATAAAAAGAAGATTTTGGC
CAGGCACGGTGGCTCATGCCTGTAATTTCAGCACTTTGGGAGGCCGAGGTGGGCAGATCACAAGGTCAGGAGTTCAAGACCAGCCTGGCC
AGTATGTTGAAACCCCATCTCTATTAAAAATACAAAAATTAGCCAGGCGTGGTGGTGCATGCCTGTAGACCCAGCTACTCAGGAGGCTGA
GGCAGAAGAACTGCTTGAGCCCAGGAGGCAGAGGTTGCAGTGAGCAGAGATTGTGCCACTGCACTCCAGCCTAGGCGACAGAGAGAGACT
CCGTCTCAAAAAAAAAAAAAAGATTTTGTTTCATTTCATAGCACAAATTTAGAGGCATTGAGTTGACCATTTCTAGTTTCTATACCTGAA

>60002_60002_7_NPNT-PPA2_NPNT_chr4_106848585_ENST00000427316_PPA2_chr4_106377902_ENST00000341695_length(amino acids)=427AA_BP=145
MLRPRASPLSSGSGSSSPGGEGWGFLETLRGAPPIGAHHPNLFLARHCAAPQDPLPNMDFLLALVLVSSLYLQAAAEFDGRWPRQIVSSI
GLCRYGGRIDCCWGWARQSWGQCQPVCQPRCKHGECIGPNKCKCHPGYAGKTCNQENVTGHYISPFHDIPLKVNSKEENGIPMKKARNDE
YENLFNMIVEIPRWTNAKMEIATKEPMNPIKQYVKDGKLRYVANIFPYKGYIWNYGTLPQTWEDPHEKDKSTNCFGDNDPIDVCEIGSKI
LSCGEVIHVKILGILALIDEGETDWKLIAINANDPEASKFHDIDDVKKFKPGYLEATLNWFRLYKVPDGKPENQFAFNGEFKNKAFALEV

--------------------------------------------------------------
>60002_60002_8_NPNT-PPA2_NPNT_chr4_106848585_ENST00000427316_PPA2_chr4_106377902_ENST00000348706_length(transcript)=1720nt_BP=477nt
AGAAGGGAGCGGGAGGGGGCTCCGGGCGCCGCGCAGCAGACCTGCTCCGGCCGCGCGCCTCGCCGCTGTCCTCCGGGAGCGGCAGCAGTA
GCCCGGGCGGCGAGGGCTGGGGGTTCCTCGAGACTCTCAGAGGGGCGCCTCCCATCGGCGCCCACCACCCCAACCTGTTCCTCGCGCGCC
ACTGCGCTGCGCCCCAGGACCCGCTGCCCAACATGGATTTTCTCCTGGCGCTGGTGCTGGTATCCTCGCTCTACCTGCAGGCGGCCGCCG
AGTTCGACGGGAGGTGGCCCAGGCAAATAGTGTCATCGATTGGCCTATGTCGTTATGGTGGGAGGATTGACTGCTGCTGGGGCTGGGCTC
GCCAGTCTTGGGGACAGTGTCAGCCTGTGTGCCAACCACGATGCAAACATGGTGAATGTATCGGGCCAAACAAGTGCAAGTGTCATCCTG
GTTATGCTGGAAAAACCTGTAATCAAGAGAATGTAACTGGTCACTACATTTCCCCCTTTCATGATATTCCTCTGAAGGTGAACTCTAAAG
AGGAAAATGGCATTCCTATGAAGAAAGCACGAAATGATGAATATGAGAATCTGTTTAATATGATTGTAGAAATACCTCGGTGGACAAATG
CTAAAATGGAGATTGCCACCAAGGAGCCAATGAATCCCATTAAACAATATGTAAAGGATGGAAAGCTACGCTATGTGGCGAATATCTTCC
CTTACAAGGGTTATATATGGAATTATGGTACCCTCCCTCAGATTCTTTCTTGTGGAGAAGTTATTCATGTGAAGATCCTTGGAATTTTGG
CTCTTATTGATGAAGGTGAAACAGATTGGAAATTAATTGCTATCAATGCGAATGATCCTGAAGCCTCAAAGTTTCATGATATTGATGATG
TTAAGAAGTTCAAACCGGGTTACCTGGAAGCTACTCTTAATTGGTTTAGATTATATAAGGTACCAGATGGAAAACCAGAAAACCAGTTTG
CTTTTAATGGAGAATTCAAAAACAAGGCTTTTGCTCTTGAAGTTATTAAATCCACTCATCAATGTTGGAAAGCATTGCTTATGAAGAAGT
GTAATGGAGGAGCTATAAATTGCACAAACGTGCAGATATCTGATAGCCCTTTCCGTTGCACTCAAGAGGAAGCAAGATCATTAGTTGAAT
CGGTATCATCTTCACCAAATAAAGAAAGTAATGAAGAAGAGCAAGTGTGGCACTTCCTTGGCAAGTGATTGAAACATCTGAAATTCTGCT
GTCAAGATTCCCATCTCTAAGGACTCCAAGTGCTAGAGACAAGGGGGTCTATGAGCATTTACTGACTTCCTGTTAAAACTTCATTTTTTC
AAACTTTTTGAGCTATGCAATATATAAATAAACAGTAAGAATTTTAAATTACTCTCCTTTGGACATTTATTGATATAAAAAGAAGATTTT
GGCCAGGCACGGTGGCTCATGCCTGTAATTTCAGCACTTTGGGAGGCCGAGGTGGGCAGATCACAAGGTCAGGAGTTCAAGACCAGCCTG
GCCAGTATGTTGAAACCCCATCTCTATTAAAAATACAAAAATTAGCCAGGCGTGGTGGTGCATGCCTGTAGACCCAGCTACTCAGGAGGC
TGAGGCAGAAGAACTGCTTGAGCCCAGGAGGCAGAGGTTGCAGTGAGCAGAGATTGTGCCACTGCACTCCAGCCTAGGCGACAGAGAGAG

>60002_60002_8_NPNT-PPA2_NPNT_chr4_106848585_ENST00000427316_PPA2_chr4_106377902_ENST00000348706_length(amino acids)=398AA_BP=145
MLRPRASPLSSGSGSSSPGGEGWGFLETLRGAPPIGAHHPNLFLARHCAAPQDPLPNMDFLLALVLVSSLYLQAAAEFDGRWPRQIVSSI
GLCRYGGRIDCCWGWARQSWGQCQPVCQPRCKHGECIGPNKCKCHPGYAGKTCNQENVTGHYISPFHDIPLKVNSKEENGIPMKKARNDE
YENLFNMIVEIPRWTNAKMEIATKEPMNPIKQYVKDGKLRYVANIFPYKGYIWNYGTLPQILSCGEVIHVKILGILALIDEGETDWKLIA
INANDPEASKFHDIDDVKKFKPGYLEATLNWFRLYKVPDGKPENQFAFNGEFKNKAFALEVIKSTHQCWKALLMKKCNGGAINCTNVQIS

--------------------------------------------------------------
>60002_60002_9_NPNT-PPA2_NPNT_chr4_106848585_ENST00000427316_PPA2_chr4_106377902_ENST00000432483_length(transcript)=1179nt_BP=477nt
AGAAGGGAGCGGGAGGGGGCTCCGGGCGCCGCGCAGCAGACCTGCTCCGGCCGCGCGCCTCGCCGCTGTCCTCCGGGAGCGGCAGCAGTA
GCCCGGGCGGCGAGGGCTGGGGGTTCCTCGAGACTCTCAGAGGGGCGCCTCCCATCGGCGCCCACCACCCCAACCTGTTCCTCGCGCGCC
ACTGCGCTGCGCCCCAGGACCCGCTGCCCAACATGGATTTTCTCCTGGCGCTGGTGCTGGTATCCTCGCTCTACCTGCAGGCGGCCGCCG
AGTTCGACGGGAGGTGGCCCAGGCAAATAGTGTCATCGATTGGCCTATGTCGTTATGGTGGGAGGATTGACTGCTGCTGGGGCTGGGCTC
GCCAGTCTTGGGGACAGTGTCAGCCTGTGTGCCAACCACGATGCAAACATGGTGAATGTATCGGGCCAAACAAGTGCAAGTGTCATCCTG
GTTATGCTGGAAAAACCTGTAATCAAGAGAATGTAACTGGTCACTACATTTCCCCCTTTCATGATATTCCTCTGAAGGTGAACTCTAAAG
AGATTCTTTCTTGTGGAGAAGTTATTCATGTGAAGATCCTTGGAATTTTGGCTCTTATTGATGAAGGTGAAACAGATTGGAAATTAATTG
CTATCAATGCGAATGATCCTGAAGCCTCAAAGTTTCATGATATTGATGATGTTAAGAAGTTCAAACCGGGTTACCTGGAAGCTACTCTTA
ATTGGTTTAGATTATATAAGGTACCAGATGGAAAACCAGAAAACCAGTTTGCTTTTAATGGAGAATTCAAAAACAAGGCTTTTGCTCTTG
AAGTTATTAAATCCACTCATCAATGTTGGAAAGCATTGCTTATGAAGAAGTGTAATGGAGGAGCTATAAATTGCACAAACGTGCAGATAT
CTGATAGCCCTTTCCGTTGCACTCAAGAGGAAGCAAGATCATTAGTTGAATCGGTATCATCTTCACCAAATAAAGAAAGTAATGAAGAAG
AGCAAGTGTGGCACTTCCTTGGCAAGTGATTGAAACATCTGAAATTCTGCTGTCAAGATTCCCATCTCTAAGGACTCCAAGTGCTAGAGA
CAAGGGGGTCTATGAGCATTTACTGACTTCCTGTTAAAACTTCATTTTTTCAAACTTTTTGAGCTATGCAATATATAAATAAACAGTAAG

>60002_60002_9_NPNT-PPA2_NPNT_chr4_106848585_ENST00000427316_PPA2_chr4_106377902_ENST00000432483_length(amino acids)=325AA_BP=145
MLRPRASPLSSGSGSSSPGGEGWGFLETLRGAPPIGAHHPNLFLARHCAAPQDPLPNMDFLLALVLVSSLYLQAAAEFDGRWPRQIVSSI
GLCRYGGRIDCCWGWARQSWGQCQPVCQPRCKHGECIGPNKCKCHPGYAGKTCNQENVTGHYISPFHDIPLKVNSKEILSCGEVIHVKIL
GILALIDEGETDWKLIAINANDPEASKFHDIDDVKKFKPGYLEATLNWFRLYKVPDGKPENQFAFNGEFKNKAFALEVIKSTHQCWKALL

--------------------------------------------------------------
>60002_60002_10_NPNT-PPA2_NPNT_chr4_106848585_ENST00000453617_PPA2_chr4_106377902_ENST00000341695_length(transcript)=2025nt_BP=529nt
TAGAAGGGAGCGGGAGGGGGCTCCGGGCGCCGCGCAGCAGACCTGCTCCGGCCGCGCGCCTCGCCGCTGTCCTCCGGGAGCGGCAGCAGT
AGCCCGGGCGGCGAGGGCTGGGGGTTCCTCGAGACTCTCAGAGGGGCGCCTCCCATCGGCGCCCACCACCCCAACCTGTTCCTCGCGCGC
CACTGCGCTGCGCCCCAGGACCCGCTGCCCAACATGGATTTTCTCCTGGCGCTGGTGCTGGTATCCTCGCTCTACCTGCAGGCGGCCGCC
GAGTTCGACGGGAGGTGGCCCAGGCAAATAGTGTCATCGATTGGCCTATGTCGTTATGGTGGGAGGATTGACTGCTGCTGGGGCTGGGCT
CGCCAGTCTTGGGGACAGTGTCAGCCTTTCTACGTCTTAAGGCAGAGAATAGCCAGGATAAGGTGCCAGCTCAAAGCTGTGTGCCAACCA
CGATGCAAACATGGTGAATGTATCGGGCCAAACAAGTGCAAGTGTCATCCTGGTTATGCTGGAAAAACCTGTAATCAAGAGAATGTAACT
GGTCACTACATTTCCCCCTTTCATGATATTCCTCTGAAGGTGAACTCTAAAGAGGAAAATGGCATTCCTATGAAGAAAGCACGAAATGAT
GAATATGAGAATCTGTTTAATATGATTGTAGAAATACCTCGGTGGACAAATGCTAAAATGGAGATTGCCACCAAGGAGCCAATGAATCCC
ATTAAACAATATGTAAAGGATGGAAAGCTACGCTATGTGGCGAATATCTTCCCTTACAAGGGTTATATATGGAATTATGGTACCCTCCCT
CAGACTTGGGAAGATCCCCATGAAAAAGATAAGAGCACGAACTGCTTTGGAGATAATGATCCTATTGATGTTTGCGAAATAGGCTCAAAG
ATTCTTTCTTGTGGAGAAGTTATTCATGTGAAGATCCTTGGAATTTTGGCTCTTATTGATGAAGGTGAAACAGATTGGAAATTAATTGCT
ATCAATGCGAATGATCCTGAAGCCTCAAAGTTTCATGATATTGATGATGTTAAGAAGTTCAAACCGGGTTACCTGGAAGCTACTCTTAAT
TGGTTTAGATTATATAAGGTACCAGATGGAAAACCAGAAAACCAGTTTGCTTTTAATGGAGAATTCAAAAACAAGGCTTTTGCTCTTGAA
GTTATTAAATCCACTCATCAATGTTGGAAAGCATTGCTTATGAAGAAGTGTAATGGAGGAGCTATAAATTGCACAAACGTGCAGATATCT
GATAGCCCTTTCCGTTGCACTCAAGAGGAAGCAAGATCATTAGTTGAATCGGTATCATCTTCACCAAATAAAGAAAGTAATGAAGAAGAG
CAAGTGTGGCACTTCCTTGGCAAGTGATTGAAACATCTGAAATTCTGCTGTCAAGATTCCCATCTCTAAGGACTCCAAGTGCTAGAGACA
AGGGGGTCTATGAGCATTTACTGACTTCCTGTTAAAACTTCATTTTTTCAAACTTTTTGAGCTATGCAATATATAAATAAACAGTAAGAA
TTTTAAATTACTCTCCTTTGGACATTTATTGATATAAAAAGAAGATTTTGGCCAGGCACGGTGGCTCATGCCTGTAATTTCAGCACTTTG
GGAGGCCGAGGTGGGCAGATCACAAGGTCAGGAGTTCAAGACCAGCCTGGCCAGTATGTTGAAACCCCATCTCTATTAAAAATACAAAAA
TTAGCCAGGCGTGGTGGTGCATGCCTGTAGACCCAGCTACTCAGGAGGCTGAGGCAGAAGAACTGCTTGAGCCCAGGAGGCAGAGGTTGC
AGTGAGCAGAGATTGTGCCACTGCACTCCAGCCTAGGCGACAGAGAGAGACTCCGTCTCAAAAAAAAAAAAAAGATTTTGTTTCATTTCA
TAGCACAAATTTAGAGGCATTGAGTTGACCATTTCTAGTTTCTATACCTGAAGGAACCCATTGATTTTACCAGTTTTTATTTCTGTAGAT

>60002_60002_10_NPNT-PPA2_NPNT_chr4_106848585_ENST00000453617_PPA2_chr4_106377902_ENST00000341695_length(amino acids)=444AA_BP=162
MLRPRASPLSSGSGSSSPGGEGWGFLETLRGAPPIGAHHPNLFLARHCAAPQDPLPNMDFLLALVLVSSLYLQAAAEFDGRWPRQIVSSI
GLCRYGGRIDCCWGWARQSWGQCQPFYVLRQRIARIRCQLKAVCQPRCKHGECIGPNKCKCHPGYAGKTCNQENVTGHYISPFHDIPLKV
NSKEENGIPMKKARNDEYENLFNMIVEIPRWTNAKMEIATKEPMNPIKQYVKDGKLRYVANIFPYKGYIWNYGTLPQTWEDPHEKDKSTN
CFGDNDPIDVCEIGSKILSCGEVIHVKILGILALIDEGETDWKLIAINANDPEASKFHDIDDVKKFKPGYLEATLNWFRLYKVPDGKPEN

--------------------------------------------------------------
>60002_60002_11_NPNT-PPA2_NPNT_chr4_106848585_ENST00000453617_PPA2_chr4_106377902_ENST00000348706_length(transcript)=1772nt_BP=529nt
TAGAAGGGAGCGGGAGGGGGCTCCGGGCGCCGCGCAGCAGACCTGCTCCGGCCGCGCGCCTCGCCGCTGTCCTCCGGGAGCGGCAGCAGT
AGCCCGGGCGGCGAGGGCTGGGGGTTCCTCGAGACTCTCAGAGGGGCGCCTCCCATCGGCGCCCACCACCCCAACCTGTTCCTCGCGCGC
CACTGCGCTGCGCCCCAGGACCCGCTGCCCAACATGGATTTTCTCCTGGCGCTGGTGCTGGTATCCTCGCTCTACCTGCAGGCGGCCGCC
GAGTTCGACGGGAGGTGGCCCAGGCAAATAGTGTCATCGATTGGCCTATGTCGTTATGGTGGGAGGATTGACTGCTGCTGGGGCTGGGCT
CGCCAGTCTTGGGGACAGTGTCAGCCTTTCTACGTCTTAAGGCAGAGAATAGCCAGGATAAGGTGCCAGCTCAAAGCTGTGTGCCAACCA
CGATGCAAACATGGTGAATGTATCGGGCCAAACAAGTGCAAGTGTCATCCTGGTTATGCTGGAAAAACCTGTAATCAAGAGAATGTAACT
GGTCACTACATTTCCCCCTTTCATGATATTCCTCTGAAGGTGAACTCTAAAGAGGAAAATGGCATTCCTATGAAGAAAGCACGAAATGAT
GAATATGAGAATCTGTTTAATATGATTGTAGAAATACCTCGGTGGACAAATGCTAAAATGGAGATTGCCACCAAGGAGCCAATGAATCCC
ATTAAACAATATGTAAAGGATGGAAAGCTACGCTATGTGGCGAATATCTTCCCTTACAAGGGTTATATATGGAATTATGGTACCCTCCCT
CAGATTCTTTCTTGTGGAGAAGTTATTCATGTGAAGATCCTTGGAATTTTGGCTCTTATTGATGAAGGTGAAACAGATTGGAAATTAATT
GCTATCAATGCGAATGATCCTGAAGCCTCAAAGTTTCATGATATTGATGATGTTAAGAAGTTCAAACCGGGTTACCTGGAAGCTACTCTT
AATTGGTTTAGATTATATAAGGTACCAGATGGAAAACCAGAAAACCAGTTTGCTTTTAATGGAGAATTCAAAAACAAGGCTTTTGCTCTT
GAAGTTATTAAATCCACTCATCAATGTTGGAAAGCATTGCTTATGAAGAAGTGTAATGGAGGAGCTATAAATTGCACAAACGTGCAGATA
TCTGATAGCCCTTTCCGTTGCACTCAAGAGGAAGCAAGATCATTAGTTGAATCGGTATCATCTTCACCAAATAAAGAAAGTAATGAAGAA
GAGCAAGTGTGGCACTTCCTTGGCAAGTGATTGAAACATCTGAAATTCTGCTGTCAAGATTCCCATCTCTAAGGACTCCAAGTGCTAGAG
ACAAGGGGGTCTATGAGCATTTACTGACTTCCTGTTAAAACTTCATTTTTTCAAACTTTTTGAGCTATGCAATATATAAATAAACAGTAA
GAATTTTAAATTACTCTCCTTTGGACATTTATTGATATAAAAAGAAGATTTTGGCCAGGCACGGTGGCTCATGCCTGTAATTTCAGCACT
TTGGGAGGCCGAGGTGGGCAGATCACAAGGTCAGGAGTTCAAGACCAGCCTGGCCAGTATGTTGAAACCCCATCTCTATTAAAAATACAA
AAATTAGCCAGGCGTGGTGGTGCATGCCTGTAGACCCAGCTACTCAGGAGGCTGAGGCAGAAGAACTGCTTGAGCCCAGGAGGCAGAGGT

>60002_60002_11_NPNT-PPA2_NPNT_chr4_106848585_ENST00000453617_PPA2_chr4_106377902_ENST00000348706_length(amino acids)=415AA_BP=162
MLRPRASPLSSGSGSSSPGGEGWGFLETLRGAPPIGAHHPNLFLARHCAAPQDPLPNMDFLLALVLVSSLYLQAAAEFDGRWPRQIVSSI
GLCRYGGRIDCCWGWARQSWGQCQPFYVLRQRIARIRCQLKAVCQPRCKHGECIGPNKCKCHPGYAGKTCNQENVTGHYISPFHDIPLKV
NSKEENGIPMKKARNDEYENLFNMIVEIPRWTNAKMEIATKEPMNPIKQYVKDGKLRYVANIFPYKGYIWNYGTLPQILSCGEVIHVKIL
GILALIDEGETDWKLIAINANDPEASKFHDIDDVKKFKPGYLEATLNWFRLYKVPDGKPENQFAFNGEFKNKAFALEVIKSTHQCWKALL

--------------------------------------------------------------
>60002_60002_12_NPNT-PPA2_NPNT_chr4_106848585_ENST00000453617_PPA2_chr4_106377902_ENST00000432483_length(transcript)=1231nt_BP=529nt
TAGAAGGGAGCGGGAGGGGGCTCCGGGCGCCGCGCAGCAGACCTGCTCCGGCCGCGCGCCTCGCCGCTGTCCTCCGGGAGCGGCAGCAGT
AGCCCGGGCGGCGAGGGCTGGGGGTTCCTCGAGACTCTCAGAGGGGCGCCTCCCATCGGCGCCCACCACCCCAACCTGTTCCTCGCGCGC
CACTGCGCTGCGCCCCAGGACCCGCTGCCCAACATGGATTTTCTCCTGGCGCTGGTGCTGGTATCCTCGCTCTACCTGCAGGCGGCCGCC
GAGTTCGACGGGAGGTGGCCCAGGCAAATAGTGTCATCGATTGGCCTATGTCGTTATGGTGGGAGGATTGACTGCTGCTGGGGCTGGGCT
CGCCAGTCTTGGGGACAGTGTCAGCCTTTCTACGTCTTAAGGCAGAGAATAGCCAGGATAAGGTGCCAGCTCAAAGCTGTGTGCCAACCA
CGATGCAAACATGGTGAATGTATCGGGCCAAACAAGTGCAAGTGTCATCCTGGTTATGCTGGAAAAACCTGTAATCAAGAGAATGTAACT
GGTCACTACATTTCCCCCTTTCATGATATTCCTCTGAAGGTGAACTCTAAAGAGATTCTTTCTTGTGGAGAAGTTATTCATGTGAAGATC
CTTGGAATTTTGGCTCTTATTGATGAAGGTGAAACAGATTGGAAATTAATTGCTATCAATGCGAATGATCCTGAAGCCTCAAAGTTTCAT
GATATTGATGATGTTAAGAAGTTCAAACCGGGTTACCTGGAAGCTACTCTTAATTGGTTTAGATTATATAAGGTACCAGATGGAAAACCA
GAAAACCAGTTTGCTTTTAATGGAGAATTCAAAAACAAGGCTTTTGCTCTTGAAGTTATTAAATCCACTCATCAATGTTGGAAAGCATTG
CTTATGAAGAAGTGTAATGGAGGAGCTATAAATTGCACAAACGTGCAGATATCTGATAGCCCTTTCCGTTGCACTCAAGAGGAAGCAAGA
TCATTAGTTGAATCGGTATCATCTTCACCAAATAAAGAAAGTAATGAAGAAGAGCAAGTGTGGCACTTCCTTGGCAAGTGATTGAAACAT
CTGAAATTCTGCTGTCAAGATTCCCATCTCTAAGGACTCCAAGTGCTAGAGACAAGGGGGTCTATGAGCATTTACTGACTTCCTGTTAAA

>60002_60002_12_NPNT-PPA2_NPNT_chr4_106848585_ENST00000453617_PPA2_chr4_106377902_ENST00000432483_length(amino acids)=342AA_BP=162
MLRPRASPLSSGSGSSSPGGEGWGFLETLRGAPPIGAHHPNLFLARHCAAPQDPLPNMDFLLALVLVSSLYLQAAAEFDGRWPRQIVSSI
GLCRYGGRIDCCWGWARQSWGQCQPFYVLRQRIARIRCQLKAVCQPRCKHGECIGPNKCKCHPGYAGKTCNQENVTGHYISPFHDIPLKV
NSKEILSCGEVIHVKILGILALIDEGETDWKLIAINANDPEASKFHDIDDVKKFKPGYLEATLNWFRLYKVPDGKPENQFAFNGEFKNKA

--------------------------------------------------------------
>60002_60002_13_NPNT-PPA2_NPNT_chr4_106848585_ENST00000506666_PPA2_chr4_106377902_ENST00000341695_length(transcript)=1921nt_BP=425nt
GCGCGCCTCGCCGCTGTCCTCCGGGAGCGGCAGCAGTAGCCCGGGCGGCGAGGGCTGGGGGTTCCTCGAGACTCTCAGAGGGGCGCCTCC
CATCGGCGCCCACCACCCCAACCTGTTCCTCGCGCGCCACTGCGCTGCGCCCCAGGACCCGCTGCCCAACATGGATTTTCTCCTGGCGCT
GGTGCTGGTATCCTCGCTCTACCTGCAGGCGGCCGCCGAGTTCGACGGGAGGTGGCCCAGGCAAATAGTGTCATCGATTGGCCTATGTCG
TTATGGTGGGAGGATTGACTGCTGCTGGGGCTGGGCTCGCCAGTCTTGGGGACAGTGTCAGCCTGTGTGCCAACCACGATGCAAACATGG
TGAATGTATCGGGCCAAACAAGTGCAAGTGTCATCCTGGTTATGCTGGAAAAACCTGTAATCAAGAGAATGTAACTGGTCACTACATTTC
CCCCTTTCATGATATTCCTCTGAAGGTGAACTCTAAAGAGGAAAATGGCATTCCTATGAAGAAAGCACGAAATGATGAATATGAGAATCT
GTTTAATATGATTGTAGAAATACCTCGGTGGACAAATGCTAAAATGGAGATTGCCACCAAGGAGCCAATGAATCCCATTAAACAATATGT
AAAGGATGGAAAGCTACGCTATGTGGCGAATATCTTCCCTTACAAGGGTTATATATGGAATTATGGTACCCTCCCTCAGACTTGGGAAGA
TCCCCATGAAAAAGATAAGAGCACGAACTGCTTTGGAGATAATGATCCTATTGATGTTTGCGAAATAGGCTCAAAGATTCTTTCTTGTGG
AGAAGTTATTCATGTGAAGATCCTTGGAATTTTGGCTCTTATTGATGAAGGTGAAACAGATTGGAAATTAATTGCTATCAATGCGAATGA
TCCTGAAGCCTCAAAGTTTCATGATATTGATGATGTTAAGAAGTTCAAACCGGGTTACCTGGAAGCTACTCTTAATTGGTTTAGATTATA
TAAGGTACCAGATGGAAAACCAGAAAACCAGTTTGCTTTTAATGGAGAATTCAAAAACAAGGCTTTTGCTCTTGAAGTTATTAAATCCAC
TCATCAATGTTGGAAAGCATTGCTTATGAAGAAGTGTAATGGAGGAGCTATAAATTGCACAAACGTGCAGATATCTGATAGCCCTTTCCG
TTGCACTCAAGAGGAAGCAAGATCATTAGTTGAATCGGTATCATCTTCACCAAATAAAGAAAGTAATGAAGAAGAGCAAGTGTGGCACTT
CCTTGGCAAGTGATTGAAACATCTGAAATTCTGCTGTCAAGATTCCCATCTCTAAGGACTCCAAGTGCTAGAGACAAGGGGGTCTATGAG
CATTTACTGACTTCCTGTTAAAACTTCATTTTTTCAAACTTTTTGAGCTATGCAATATATAAATAAACAGTAAGAATTTTAAATTACTCT
CCTTTGGACATTTATTGATATAAAAAGAAGATTTTGGCCAGGCACGGTGGCTCATGCCTGTAATTTCAGCACTTTGGGAGGCCGAGGTGG
GCAGATCACAAGGTCAGGAGTTCAAGACCAGCCTGGCCAGTATGTTGAAACCCCATCTCTATTAAAAATACAAAAATTAGCCAGGCGTGG
TGGTGCATGCCTGTAGACCCAGCTACTCAGGAGGCTGAGGCAGAAGAACTGCTTGAGCCCAGGAGGCAGAGGTTGCAGTGAGCAGAGATT
GTGCCACTGCACTCCAGCCTAGGCGACAGAGAGAGACTCCGTCTCAAAAAAAAAAAAAAGATTTTGTTTCATTTCATAGCACAAATTTAG
AGGCATTGAGTTGACCATTTCTAGTTTCTATACCTGAAGGAACCCATTGATTTTACCAGTTTTTATTTCTGTAGATTGGATGTAAAAATC

>60002_60002_13_NPNT-PPA2_NPNT_chr4_106848585_ENST00000506666_PPA2_chr4_106377902_ENST00000341695_length(amino acids)=419AA_BP=137
MSSGSGSSSPGGEGWGFLETLRGAPPIGAHHPNLFLARHCAAPQDPLPNMDFLLALVLVSSLYLQAAAEFDGRWPRQIVSSIGLCRYGGR
IDCCWGWARQSWGQCQPVCQPRCKHGECIGPNKCKCHPGYAGKTCNQENVTGHYISPFHDIPLKVNSKEENGIPMKKARNDEYENLFNMI
VEIPRWTNAKMEIATKEPMNPIKQYVKDGKLRYVANIFPYKGYIWNYGTLPQTWEDPHEKDKSTNCFGDNDPIDVCEIGSKILSCGEVIH
VKILGILALIDEGETDWKLIAINANDPEASKFHDIDDVKKFKPGYLEATLNWFRLYKVPDGKPENQFAFNGEFKNKAFALEVIKSTHQCW

--------------------------------------------------------------
>60002_60002_14_NPNT-PPA2_NPNT_chr4_106848585_ENST00000506666_PPA2_chr4_106377902_ENST00000348706_length(transcript)=1668nt_BP=425nt
GCGCGCCTCGCCGCTGTCCTCCGGGAGCGGCAGCAGTAGCCCGGGCGGCGAGGGCTGGGGGTTCCTCGAGACTCTCAGAGGGGCGCCTCC
CATCGGCGCCCACCACCCCAACCTGTTCCTCGCGCGCCACTGCGCTGCGCCCCAGGACCCGCTGCCCAACATGGATTTTCTCCTGGCGCT
GGTGCTGGTATCCTCGCTCTACCTGCAGGCGGCCGCCGAGTTCGACGGGAGGTGGCCCAGGCAAATAGTGTCATCGATTGGCCTATGTCG
TTATGGTGGGAGGATTGACTGCTGCTGGGGCTGGGCTCGCCAGTCTTGGGGACAGTGTCAGCCTGTGTGCCAACCACGATGCAAACATGG
TGAATGTATCGGGCCAAACAAGTGCAAGTGTCATCCTGGTTATGCTGGAAAAACCTGTAATCAAGAGAATGTAACTGGTCACTACATTTC
CCCCTTTCATGATATTCCTCTGAAGGTGAACTCTAAAGAGGAAAATGGCATTCCTATGAAGAAAGCACGAAATGATGAATATGAGAATCT
GTTTAATATGATTGTAGAAATACCTCGGTGGACAAATGCTAAAATGGAGATTGCCACCAAGGAGCCAATGAATCCCATTAAACAATATGT
AAAGGATGGAAAGCTACGCTATGTGGCGAATATCTTCCCTTACAAGGGTTATATATGGAATTATGGTACCCTCCCTCAGATTCTTTCTTG
TGGAGAAGTTATTCATGTGAAGATCCTTGGAATTTTGGCTCTTATTGATGAAGGTGAAACAGATTGGAAATTAATTGCTATCAATGCGAA
TGATCCTGAAGCCTCAAAGTTTCATGATATTGATGATGTTAAGAAGTTCAAACCGGGTTACCTGGAAGCTACTCTTAATTGGTTTAGATT
ATATAAGGTACCAGATGGAAAACCAGAAAACCAGTTTGCTTTTAATGGAGAATTCAAAAACAAGGCTTTTGCTCTTGAAGTTATTAAATC
CACTCATCAATGTTGGAAAGCATTGCTTATGAAGAAGTGTAATGGAGGAGCTATAAATTGCACAAACGTGCAGATATCTGATAGCCCTTT
CCGTTGCACTCAAGAGGAAGCAAGATCATTAGTTGAATCGGTATCATCTTCACCAAATAAAGAAAGTAATGAAGAAGAGCAAGTGTGGCA
CTTCCTTGGCAAGTGATTGAAACATCTGAAATTCTGCTGTCAAGATTCCCATCTCTAAGGACTCCAAGTGCTAGAGACAAGGGGGTCTAT
GAGCATTTACTGACTTCCTGTTAAAACTTCATTTTTTCAAACTTTTTGAGCTATGCAATATATAAATAAACAGTAAGAATTTTAAATTAC
TCTCCTTTGGACATTTATTGATATAAAAAGAAGATTTTGGCCAGGCACGGTGGCTCATGCCTGTAATTTCAGCACTTTGGGAGGCCGAGG
TGGGCAGATCACAAGGTCAGGAGTTCAAGACCAGCCTGGCCAGTATGTTGAAACCCCATCTCTATTAAAAATACAAAAATTAGCCAGGCG
TGGTGGTGCATGCCTGTAGACCCAGCTACTCAGGAGGCTGAGGCAGAAGAACTGCTTGAGCCCAGGAGGCAGAGGTTGCAGTGAGCAGAG

>60002_60002_14_NPNT-PPA2_NPNT_chr4_106848585_ENST00000506666_PPA2_chr4_106377902_ENST00000348706_length(amino acids)=390AA_BP=137
MSSGSGSSSPGGEGWGFLETLRGAPPIGAHHPNLFLARHCAAPQDPLPNMDFLLALVLVSSLYLQAAAEFDGRWPRQIVSSIGLCRYGGR
IDCCWGWARQSWGQCQPVCQPRCKHGECIGPNKCKCHPGYAGKTCNQENVTGHYISPFHDIPLKVNSKEENGIPMKKARNDEYENLFNMI
VEIPRWTNAKMEIATKEPMNPIKQYVKDGKLRYVANIFPYKGYIWNYGTLPQILSCGEVIHVKILGILALIDEGETDWKLIAINANDPEA
SKFHDIDDVKKFKPGYLEATLNWFRLYKVPDGKPENQFAFNGEFKNKAFALEVIKSTHQCWKALLMKKCNGGAINCTNVQISDSPFRCTQ

--------------------------------------------------------------
>60002_60002_15_NPNT-PPA2_NPNT_chr4_106848585_ENST00000506666_PPA2_chr4_106377902_ENST00000432483_length(transcript)=1127nt_BP=425nt
GCGCGCCTCGCCGCTGTCCTCCGGGAGCGGCAGCAGTAGCCCGGGCGGCGAGGGCTGGGGGTTCCTCGAGACTCTCAGAGGGGCGCCTCC
CATCGGCGCCCACCACCCCAACCTGTTCCTCGCGCGCCACTGCGCTGCGCCCCAGGACCCGCTGCCCAACATGGATTTTCTCCTGGCGCT
GGTGCTGGTATCCTCGCTCTACCTGCAGGCGGCCGCCGAGTTCGACGGGAGGTGGCCCAGGCAAATAGTGTCATCGATTGGCCTATGTCG
TTATGGTGGGAGGATTGACTGCTGCTGGGGCTGGGCTCGCCAGTCTTGGGGACAGTGTCAGCCTGTGTGCCAACCACGATGCAAACATGG
TGAATGTATCGGGCCAAACAAGTGCAAGTGTCATCCTGGTTATGCTGGAAAAACCTGTAATCAAGAGAATGTAACTGGTCACTACATTTC
CCCCTTTCATGATATTCCTCTGAAGGTGAACTCTAAAGAGATTCTTTCTTGTGGAGAAGTTATTCATGTGAAGATCCTTGGAATTTTGGC
TCTTATTGATGAAGGTGAAACAGATTGGAAATTAATTGCTATCAATGCGAATGATCCTGAAGCCTCAAAGTTTCATGATATTGATGATGT
TAAGAAGTTCAAACCGGGTTACCTGGAAGCTACTCTTAATTGGTTTAGATTATATAAGGTACCAGATGGAAAACCAGAAAACCAGTTTGC
TTTTAATGGAGAATTCAAAAACAAGGCTTTTGCTCTTGAAGTTATTAAATCCACTCATCAATGTTGGAAAGCATTGCTTATGAAGAAGTG
TAATGGAGGAGCTATAAATTGCACAAACGTGCAGATATCTGATAGCCCTTTCCGTTGCACTCAAGAGGAAGCAAGATCATTAGTTGAATC
GGTATCATCTTCACCAAATAAAGAAAGTAATGAAGAAGAGCAAGTGTGGCACTTCCTTGGCAAGTGATTGAAACATCTGAAATTCTGCTG
TCAAGATTCCCATCTCTAAGGACTCCAAGTGCTAGAGACAAGGGGGTCTATGAGCATTTACTGACTTCCTGTTAAAACTTCATTTTTTCA

>60002_60002_15_NPNT-PPA2_NPNT_chr4_106848585_ENST00000506666_PPA2_chr4_106377902_ENST00000432483_length(amino acids)=317AA_BP=137
MSSGSGSSSPGGEGWGFLETLRGAPPIGAHHPNLFLARHCAAPQDPLPNMDFLLALVLVSSLYLQAAAEFDGRWPRQIVSSIGLCRYGGR
IDCCWGWARQSWGQCQPVCQPRCKHGECIGPNKCKCHPGYAGKTCNQENVTGHYISPFHDIPLKVNSKEILSCGEVIHVKILGILALIDE
GETDWKLIAINANDPEASKFHDIDDVKKFKPGYLEATLNWFRLYKVPDGKPENQFAFNGEFKNKAFALEVIKSTHQCWKALLMKKCNGGA

--------------------------------------------------------------
>60002_60002_16_NPNT-PPA2_NPNT_chr4_106848585_ENST00000514622_PPA2_chr4_106377902_ENST00000341695_length(transcript)=1973nt_BP=477nt
AGAAGGGAGCGGGAGGGGGCTCCGGGCGCCGCGCAGCAGACCTGCTCCGGCCGCGCGCCTCGCCGCTGTCCTCCGGGAGCGGCAGCAGTA
GCCCGGGCGGCGAGGGCTGGGGGTTCCTCGAGACTCTCAGAGGGGCGCCTCCCATCGGCGCCCACCACCCCAACCTGTTCCTCGCGCGCC
ACTGCGCTGCGCCCCAGGACCCGCTGCCCAACATGGATTTTCTCCTGGCGCTGGTGCTGGTATCCTCGCTCTACCTGCAGGCGGCCGCCG
AGTTCGACGGGAGGTGGCCCAGGCAAATAGTGTCATCGATTGGCCTATGTCGTTATGGTGGGAGGATTGACTGCTGCTGGGGCTGGGCTC
GCCAGTCTTGGGGACAGTGTCAGCCTGTGTGCCAACCACGATGCAAACATGGTGAATGTATCGGGCCAAACAAGTGCAAGTGTCATCCTG
GTTATGCTGGAAAAACCTGTAATCAAGAGAATGTAACTGGTCACTACATTTCCCCCTTTCATGATATTCCTCTGAAGGTGAACTCTAAAG
AGGAAAATGGCATTCCTATGAAGAAAGCACGAAATGATGAATATGAGAATCTGTTTAATATGATTGTAGAAATACCTCGGTGGACAAATG
CTAAAATGGAGATTGCCACCAAGGAGCCAATGAATCCCATTAAACAATATGTAAAGGATGGAAAGCTACGCTATGTGGCGAATATCTTCC
CTTACAAGGGTTATATATGGAATTATGGTACCCTCCCTCAGACTTGGGAAGATCCCCATGAAAAAGATAAGAGCACGAACTGCTTTGGAG
ATAATGATCCTATTGATGTTTGCGAAATAGGCTCAAAGATTCTTTCTTGTGGAGAAGTTATTCATGTGAAGATCCTTGGAATTTTGGCTC
TTATTGATGAAGGTGAAACAGATTGGAAATTAATTGCTATCAATGCGAATGATCCTGAAGCCTCAAAGTTTCATGATATTGATGATGTTA
AGAAGTTCAAACCGGGTTACCTGGAAGCTACTCTTAATTGGTTTAGATTATATAAGGTACCAGATGGAAAACCAGAAAACCAGTTTGCTT
TTAATGGAGAATTCAAAAACAAGGCTTTTGCTCTTGAAGTTATTAAATCCACTCATCAATGTTGGAAAGCATTGCTTATGAAGAAGTGTA
ATGGAGGAGCTATAAATTGCACAAACGTGCAGATATCTGATAGCCCTTTCCGTTGCACTCAAGAGGAAGCAAGATCATTAGTTGAATCGG
TATCATCTTCACCAAATAAAGAAAGTAATGAAGAAGAGCAAGTGTGGCACTTCCTTGGCAAGTGATTGAAACATCTGAAATTCTGCTGTC
AAGATTCCCATCTCTAAGGACTCCAAGTGCTAGAGACAAGGGGGTCTATGAGCATTTACTGACTTCCTGTTAAAACTTCATTTTTTCAAA
CTTTTTGAGCTATGCAATATATAAATAAACAGTAAGAATTTTAAATTACTCTCCTTTGGACATTTATTGATATAAAAAGAAGATTTTGGC
CAGGCACGGTGGCTCATGCCTGTAATTTCAGCACTTTGGGAGGCCGAGGTGGGCAGATCACAAGGTCAGGAGTTCAAGACCAGCCTGGCC
AGTATGTTGAAACCCCATCTCTATTAAAAATACAAAAATTAGCCAGGCGTGGTGGTGCATGCCTGTAGACCCAGCTACTCAGGAGGCTGA
GGCAGAAGAACTGCTTGAGCCCAGGAGGCAGAGGTTGCAGTGAGCAGAGATTGTGCCACTGCACTCCAGCCTAGGCGACAGAGAGAGACT
CCGTCTCAAAAAAAAAAAAAAGATTTTGTTTCATTTCATAGCACAAATTTAGAGGCATTGAGTTGACCATTTCTAGTTTCTATACCTGAA

>60002_60002_16_NPNT-PPA2_NPNT_chr4_106848585_ENST00000514622_PPA2_chr4_106377902_ENST00000341695_length(amino acids)=427AA_BP=145
MLRPRASPLSSGSGSSSPGGEGWGFLETLRGAPPIGAHHPNLFLARHCAAPQDPLPNMDFLLALVLVSSLYLQAAAEFDGRWPRQIVSSI
GLCRYGGRIDCCWGWARQSWGQCQPVCQPRCKHGECIGPNKCKCHPGYAGKTCNQENVTGHYISPFHDIPLKVNSKEENGIPMKKARNDE
YENLFNMIVEIPRWTNAKMEIATKEPMNPIKQYVKDGKLRYVANIFPYKGYIWNYGTLPQTWEDPHEKDKSTNCFGDNDPIDVCEIGSKI
LSCGEVIHVKILGILALIDEGETDWKLIAINANDPEASKFHDIDDVKKFKPGYLEATLNWFRLYKVPDGKPENQFAFNGEFKNKAFALEV

--------------------------------------------------------------
>60002_60002_17_NPNT-PPA2_NPNT_chr4_106848585_ENST00000514622_PPA2_chr4_106377902_ENST00000348706_length(transcript)=1720nt_BP=477nt
AGAAGGGAGCGGGAGGGGGCTCCGGGCGCCGCGCAGCAGACCTGCTCCGGCCGCGCGCCTCGCCGCTGTCCTCCGGGAGCGGCAGCAGTA
GCCCGGGCGGCGAGGGCTGGGGGTTCCTCGAGACTCTCAGAGGGGCGCCTCCCATCGGCGCCCACCACCCCAACCTGTTCCTCGCGCGCC
ACTGCGCTGCGCCCCAGGACCCGCTGCCCAACATGGATTTTCTCCTGGCGCTGGTGCTGGTATCCTCGCTCTACCTGCAGGCGGCCGCCG
AGTTCGACGGGAGGTGGCCCAGGCAAATAGTGTCATCGATTGGCCTATGTCGTTATGGTGGGAGGATTGACTGCTGCTGGGGCTGGGCTC
GCCAGTCTTGGGGACAGTGTCAGCCTGTGTGCCAACCACGATGCAAACATGGTGAATGTATCGGGCCAAACAAGTGCAAGTGTCATCCTG
GTTATGCTGGAAAAACCTGTAATCAAGAGAATGTAACTGGTCACTACATTTCCCCCTTTCATGATATTCCTCTGAAGGTGAACTCTAAAG
AGGAAAATGGCATTCCTATGAAGAAAGCACGAAATGATGAATATGAGAATCTGTTTAATATGATTGTAGAAATACCTCGGTGGACAAATG
CTAAAATGGAGATTGCCACCAAGGAGCCAATGAATCCCATTAAACAATATGTAAAGGATGGAAAGCTACGCTATGTGGCGAATATCTTCC
CTTACAAGGGTTATATATGGAATTATGGTACCCTCCCTCAGATTCTTTCTTGTGGAGAAGTTATTCATGTGAAGATCCTTGGAATTTTGG
CTCTTATTGATGAAGGTGAAACAGATTGGAAATTAATTGCTATCAATGCGAATGATCCTGAAGCCTCAAAGTTTCATGATATTGATGATG
TTAAGAAGTTCAAACCGGGTTACCTGGAAGCTACTCTTAATTGGTTTAGATTATATAAGGTACCAGATGGAAAACCAGAAAACCAGTTTG
CTTTTAATGGAGAATTCAAAAACAAGGCTTTTGCTCTTGAAGTTATTAAATCCACTCATCAATGTTGGAAAGCATTGCTTATGAAGAAGT
GTAATGGAGGAGCTATAAATTGCACAAACGTGCAGATATCTGATAGCCCTTTCCGTTGCACTCAAGAGGAAGCAAGATCATTAGTTGAAT
CGGTATCATCTTCACCAAATAAAGAAAGTAATGAAGAAGAGCAAGTGTGGCACTTCCTTGGCAAGTGATTGAAACATCTGAAATTCTGCT
GTCAAGATTCCCATCTCTAAGGACTCCAAGTGCTAGAGACAAGGGGGTCTATGAGCATTTACTGACTTCCTGTTAAAACTTCATTTTTTC
AAACTTTTTGAGCTATGCAATATATAAATAAACAGTAAGAATTTTAAATTACTCTCCTTTGGACATTTATTGATATAAAAAGAAGATTTT
GGCCAGGCACGGTGGCTCATGCCTGTAATTTCAGCACTTTGGGAGGCCGAGGTGGGCAGATCACAAGGTCAGGAGTTCAAGACCAGCCTG
GCCAGTATGTTGAAACCCCATCTCTATTAAAAATACAAAAATTAGCCAGGCGTGGTGGTGCATGCCTGTAGACCCAGCTACTCAGGAGGC
TGAGGCAGAAGAACTGCTTGAGCCCAGGAGGCAGAGGTTGCAGTGAGCAGAGATTGTGCCACTGCACTCCAGCCTAGGCGACAGAGAGAG

>60002_60002_17_NPNT-PPA2_NPNT_chr4_106848585_ENST00000514622_PPA2_chr4_106377902_ENST00000348706_length(amino acids)=398AA_BP=145
MLRPRASPLSSGSGSSSPGGEGWGFLETLRGAPPIGAHHPNLFLARHCAAPQDPLPNMDFLLALVLVSSLYLQAAAEFDGRWPRQIVSSI
GLCRYGGRIDCCWGWARQSWGQCQPVCQPRCKHGECIGPNKCKCHPGYAGKTCNQENVTGHYISPFHDIPLKVNSKEENGIPMKKARNDE
YENLFNMIVEIPRWTNAKMEIATKEPMNPIKQYVKDGKLRYVANIFPYKGYIWNYGTLPQILSCGEVIHVKILGILALIDEGETDWKLIA
INANDPEASKFHDIDDVKKFKPGYLEATLNWFRLYKVPDGKPENQFAFNGEFKNKAFALEVIKSTHQCWKALLMKKCNGGAINCTNVQIS

--------------------------------------------------------------
>60002_60002_18_NPNT-PPA2_NPNT_chr4_106848585_ENST00000514622_PPA2_chr4_106377902_ENST00000432483_length(transcript)=1179nt_BP=477nt
AGAAGGGAGCGGGAGGGGGCTCCGGGCGCCGCGCAGCAGACCTGCTCCGGCCGCGCGCCTCGCCGCTGTCCTCCGGGAGCGGCAGCAGTA
GCCCGGGCGGCGAGGGCTGGGGGTTCCTCGAGACTCTCAGAGGGGCGCCTCCCATCGGCGCCCACCACCCCAACCTGTTCCTCGCGCGCC
ACTGCGCTGCGCCCCAGGACCCGCTGCCCAACATGGATTTTCTCCTGGCGCTGGTGCTGGTATCCTCGCTCTACCTGCAGGCGGCCGCCG
AGTTCGACGGGAGGTGGCCCAGGCAAATAGTGTCATCGATTGGCCTATGTCGTTATGGTGGGAGGATTGACTGCTGCTGGGGCTGGGCTC
GCCAGTCTTGGGGACAGTGTCAGCCTGTGTGCCAACCACGATGCAAACATGGTGAATGTATCGGGCCAAACAAGTGCAAGTGTCATCCTG
GTTATGCTGGAAAAACCTGTAATCAAGAGAATGTAACTGGTCACTACATTTCCCCCTTTCATGATATTCCTCTGAAGGTGAACTCTAAAG
AGATTCTTTCTTGTGGAGAAGTTATTCATGTGAAGATCCTTGGAATTTTGGCTCTTATTGATGAAGGTGAAACAGATTGGAAATTAATTG
CTATCAATGCGAATGATCCTGAAGCCTCAAAGTTTCATGATATTGATGATGTTAAGAAGTTCAAACCGGGTTACCTGGAAGCTACTCTTA
ATTGGTTTAGATTATATAAGGTACCAGATGGAAAACCAGAAAACCAGTTTGCTTTTAATGGAGAATTCAAAAACAAGGCTTTTGCTCTTG
AAGTTATTAAATCCACTCATCAATGTTGGAAAGCATTGCTTATGAAGAAGTGTAATGGAGGAGCTATAAATTGCACAAACGTGCAGATAT
CTGATAGCCCTTTCCGTTGCACTCAAGAGGAAGCAAGATCATTAGTTGAATCGGTATCATCTTCACCAAATAAAGAAAGTAATGAAGAAG
AGCAAGTGTGGCACTTCCTTGGCAAGTGATTGAAACATCTGAAATTCTGCTGTCAAGATTCCCATCTCTAAGGACTCCAAGTGCTAGAGA
CAAGGGGGTCTATGAGCATTTACTGACTTCCTGTTAAAACTTCATTTTTTCAAACTTTTTGAGCTATGCAATATATAAATAAACAGTAAG

>60002_60002_18_NPNT-PPA2_NPNT_chr4_106848585_ENST00000514622_PPA2_chr4_106377902_ENST00000432483_length(amino acids)=325AA_BP=145
MLRPRASPLSSGSGSSSPGGEGWGFLETLRGAPPIGAHHPNLFLARHCAAPQDPLPNMDFLLALVLVSSLYLQAAAEFDGRWPRQIVSSI
GLCRYGGRIDCCWGWARQSWGQCQPVCQPRCKHGECIGPNKCKCHPGYAGKTCNQENVTGHYISPFHDIPLKVNSKEILSCGEVIHVKIL
GILALIDEGETDWKLIAINANDPEASKFHDIDDVKKFKPGYLEATLNWFRLYKVPDGKPENQFAFNGEFKNKAFALEVIKSTHQCWKALL

--------------------------------------------------------------

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Fusion Gene PPI Analysis for NPNT-PPA2


check button Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in

ChiPPI page.


check button Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160)
HgeneHgene's interactorsTgeneTgene's interactors


check button - Retained PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenStill interaction with


check button - Lost PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


check button - Retained PPIs, but lost function due to frame-shift fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


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Related Drugs for NPNT-PPA2


check button Drugs targeting genes involved in this fusion gene.
(DrugBank Version 5.1.8 2021-05-08)
PartnerGeneUniProtAccDrugBank IDDrug nameDrug activityDrug typeDrug status

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Related Diseases for NPNT-PPA2


check button Diseases associated with fusion partners.
(DisGeNet 4.0)
PartnerGeneDisease IDDisease name# pubmedsSource