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Center for Computational Systems Medicine
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Fusion Gene Summary

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Fusion Gene ORF analysis

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Fusion Genomic Features

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Fusion Protein Features

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Fusion Gene Sequence

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Fusion Gene PPI analysis

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Related Drugs

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Related Diseases

Fusion gene:NRBF2-REEP3 (FusionGDB2 ID:60204)

Fusion Gene Summary for NRBF2-REEP3

check button Fusion gene summary
Fusion gene informationFusion gene name: NRBF2-REEP3
Fusion gene ID: 60204
HgeneTgene
Gene symbol

NRBF2

REEP3

Gene ID

29982

221035

Gene namenuclear receptor binding factor 2receptor accessory protein 3
SynonymsCOPR|COPR1|COPR2|NRBF-2C10orf74|Yip2b
Cytomap

10q21.3

10q21.3

Type of geneprotein-codingprotein-coding
Descriptionnuclear receptor-binding factor 2comodulator of PPAR and RXR 1comodulator of PPAR and RXR 2receptor expression-enhancing protein 3
Modification date2020031320200313
UniProtAcc

Q96F24

.
Ensembl transtripts involved in fusion geneENST00000435510, ENST00000277746, 
ENST00000298249, ENST00000373758, 
Fusion gene scores* DoF score9 X 6 X 5=2709 X 11 X 6=594
# samples 1011
** MAII scorelog2(10/270*10)=-1.43295940727611
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0		log2(11/594*10)=-2.43295940727611
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0
Context

PubMed: NRBF2 [Title/Abstract] AND REEP3 [Title/Abstract] AND fusion [Title/Abstract]

Most frequent breakpointNRBF2(64893260)-REEP3(65354538), # samples:2
Anticipated loss of major functional domain due to fusion event.
* DoF score (Degree of Frequency) = # partners X # break points X # cancer types
** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)

check button Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez
PartnerGeneGO IDGO termPubMed ID

check buttonFusion gene breakpoints across NRBF2 (5'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check buttonFusion gene breakpoints across REEP3 (3'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check button Fusion gene information from two resources (ChiTars 5.0 and ChimerDB 4.0)
* All genome coordinats were lifted-over on hg19.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
SourceDiseaseSampleHgeneHchrHbpHstrandTgeneTchrTbpTstrand
ChimerDB4BLCATCGA-XF-A9SU-01ANRBF2chr10

64893260

+REEP3chr10

65354538

+
ChimerDB4BLCATCGA-XF-A9SUNRBF2chr10

64893260

+REEP3chr10

65354538

+
ChimerDB4LUSCTCGA-58-8387NRBF2chr10

64893260

+REEP3chr10

65369946

+
ChimerDB4LUSCTCGA-58-8387NRBF2chr10

64893260

+REEP3chr10

65369947

+


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Fusion Gene ORF analysis for NRBF2-REEP3

check button Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
ORFHenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrand
Frame-shiftENST00000435510ENST00000298249NRBF2chr10

64893260

+REEP3chr10

65354538

+
Frame-shiftENST00000435510ENST00000298249NRBF2chr10

64893260

+REEP3chr10

65369946

+
Frame-shiftENST00000435510ENST00000298249NRBF2chr10

64893260

+REEP3chr10

65369947

+
Frame-shiftENST00000435510ENST00000373758NRBF2chr10

64893260

+REEP3chr10

65354538

+
Frame-shiftENST00000435510ENST00000373758NRBF2chr10

64893260

+REEP3chr10

65369946

+
Frame-shiftENST00000435510ENST00000373758NRBF2chr10

64893260

+REEP3chr10

65369947

+
In-frameENST00000277746ENST00000298249NRBF2chr10

64893260

+REEP3chr10

65354538

+
In-frameENST00000277746ENST00000298249NRBF2chr10

64893260

+REEP3chr10

65369946

+
In-frameENST00000277746ENST00000298249NRBF2chr10

64893260

+REEP3chr10

65369947

+
In-frameENST00000277746ENST00000373758NRBF2chr10

64893260

+REEP3chr10

65354538

+
In-frameENST00000277746ENST00000373758NRBF2chr10

64893260

+REEP3chr10

65369946

+
In-frameENST00000277746ENST00000373758NRBF2chr10

64893260

+REEP3chr10

65369947

+

check buttonORFfinder result based on the fusion transcript sequence of in-frame fusion genes.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandSeq length
(transcript)		BP loci
(transcript)		Predicted start
(transcript)		Predicted stop
(transcript)		Seq length
(amino acids)
ENST00000277746NRBF2chr1064893260+ENST00000298249REEP3chr1065354538+512621164873269
ENST00000277746NRBF2chr1064893260+ENST00000373758REEP3chr1065354538+512821164873269
ENST00000277746NRBF2chr1064893260+ENST00000298249REEP3chr1065369946+481421164561165
ENST00000277746NRBF2chr1064893260+ENST00000373758REEP3chr1065369946+481621164561165
ENST00000277746NRBF2chr1064893260+ENST00000298249REEP3chr1065369947+481421164561165
ENST00000277746NRBF2chr1064893260+ENST00000373758REEP3chr1065369947+481621164561165

check buttonDeepORF prediction of the coding potential based on the fusion transcript sequence of in-frame fusion genes. DeepORF is a coding potential classifier based on convolutional neural network by comparing the real Ribo-seq data. If the no-coding score < 0.5 and coding score > 0.5, then the in-frame fusion transcript is predicted as being likely translated.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandNo-coding scoreCoding score
ENST00000277746ENST00000298249NRBF2chr1064893260+REEP3chr1065354538+0.0001643620.9998356
ENST00000277746ENST00000373758NRBF2chr1064893260+REEP3chr1065354538+0.0001328590.9998671
ENST00000277746ENST00000298249NRBF2chr1064893260+REEP3chr1065369946+0.0063074690.9936925
ENST00000277746ENST00000373758NRBF2chr1064893260+REEP3chr1065369946+0.0027328990.9972671
ENST00000277746ENST00000298249NRBF2chr1064893260+REEP3chr1065369947+0.0063074690.9936925
ENST00000277746ENST00000373758NRBF2chr1064893260+REEP3chr1065369947+0.0027328990.9972671

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Fusion Genomic Features for NRBF2-REEP3


check buttonFusionAI prediction of the potential fusion gene breakpoint based on the pre-mature RNA sequence context (+/- 5kb of individual partner genes, total 20kb length sequence). FusionAI is a fusion gene breakpoint classifier based on convolutional neural network by comparing the fusion positive and negative sequence context of ~ 20K fusion gene data. From here, we can have the relative potentency of the 20K genomic sequence how individual sequnce will be likely used as the gene fusion breakpoints.
HgeneHchrHbpHstrandTgeneTchrTbpTstrand1-pp (fusion gene breakpoint)
NRBF2chr1064893260+REEP3chr1065354537+2.40E-050.99997604
NRBF2chr1064893260+REEP3chr1065354537+2.40E-050.99997604
NRBF2chr1064893260+REEP3chr1065369946+1.07E-060.9999989
NRBF2chr1064893260+REEP3chr1065354537+2.40E-050.99997604
NRBF2chr1064893260+REEP3chr1065354537+2.40E-050.99997604
NRBF2chr1064893260+REEP3chr1065369946+1.07E-060.9999989

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions. We integrated a total of 44 different types of human genomic feature loci information across five big categories including virus integration sites, repeats, structural variants, chromatin states, and gene expression regulation. More details are in help page.
genomic feature

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions that are ovelapped with the top 1% feature importance score regions. More details are in help page.
genomic feature of top 1%

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Fusion Protein Features for NRBF2-REEP3


check button Four levels of functional features of fusion genes
Go to FGviewer search page for the most frequent breakpoint (https://ccsmweb.uth.edu/FGviewer/chr10:64893260/chr10:65354538)
- FGviewer provides the online visualization of the retention search of the protein functional features across DNA, RNA, protein, and pathological levels.
- How to search
1. Put your fusion gene symbol.
2. Press the tab key until there will be shown the breakpoint information filled.
4. Go down and press 'Search' tab twice.
4. Go down to have the hyperlink of the search result.
5. Click the hyperlink.
6. See the FGviewer result for your fusion gene.
FGviewer

check buttonMain function of each fusion partner protein. (from UniProt)
HgeneTgene
NRBF2

Q96F24

.
FUNCTION: May modulate transcriptional activation by target nuclear receptors. Can act as transcriptional activator (in vitro). {ECO:0000269|PubMed:15610520}.; FUNCTION: Involved in starvation-induced autophagy probably by its association with PI3K complex I (PI3KC3-C1). However, effects has been described variably. Involved in the induction of starvation-induced autophagy (PubMed:24785657). Stabilzes PI3KC3-C1 assembly and enhances ATG14-linked lipid kinase activity of PIK3C3 (By similarity). Proposed to negatively regulate basal and starvation-induced autophagy and to inhibit PIK3C3 activity by modulating interactions in PI3KC3-C1 (PubMed:25086043). May be involved in autophagosome biogenesis (PubMed:25086043). May play a role in neural progenitor cell survival during differentiation (By similarity). {ECO:0000250|UniProtKB:Q8VCQ3, ECO:0000269|PubMed:24785657, ECO:0000269|PubMed:25086043}.FUNCTION: Transcriptional activator which is required for calcium-dependent dendritic growth and branching in cortical neurons. Recruits CREB-binding protein (CREBBP) to nuclear bodies. Component of the CREST-BRG1 complex, a multiprotein complex that regulates promoter activation by orchestrating a calcium-dependent release of a repressor complex and a recruitment of an activator complex. In resting neurons, transcription of the c-FOS promoter is inhibited by BRG1-dependent recruitment of a phospho-RB1-HDAC1 repressor complex. Upon calcium influx, RB1 is dephosphorylated by calcineurin, which leads to release of the repressor complex. At the same time, there is increased recruitment of CREBBP to the promoter by a CREST-dependent mechanism, which leads to transcriptional activation. The CREST-BRG1 complex also binds to the NR2B promoter, and activity-dependent induction of NR2B expression involves a release of HDAC1 and recruitment of CREBBP (By similarity). {ECO:0000250}.

check buttonRetention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at

download page


* Minus value of BPloci means that the break pointn is located before the CDS.
- In-frame and retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
TgeneREEP3chr10:64893260chr10:65354538ENST000003737581835_5535256.0TransmembraneHelical
TgeneREEP3chr10:64893260chr10:65354538ENST000003737581859_7935256.0TransmembraneHelical

- In-frame and not-retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneNRBF2chr10:64893260chr10:65354538ENST00000277746+14168_20910288.0Coiled coilOntology_term=ECO:0000255
HgeneNRBF2chr10:64893260chr10:65369946ENST00000277746+14168_20910288.0Coiled coilOntology_term=ECO:0000255
HgeneNRBF2chr10:64893260chr10:65369947ENST00000277746+14168_20910288.0Coiled coilOntology_term=ECO:0000255
TgeneREEP3chr10:64893260chr10:65354538ENST00000373758181_2135256.0TransmembraneHelical
TgeneREEP3chr10:64893260chr10:65369946ENST00000373758481_21139256.0TransmembraneHelical
TgeneREEP3chr10:64893260chr10:65369946ENST000003737584835_55139256.0TransmembraneHelical
TgeneREEP3chr10:64893260chr10:65369946ENST000003737584859_79139256.0TransmembraneHelical
TgeneREEP3chr10:64893260chr10:65369947ENST00000373758481_21139256.0TransmembraneHelical
TgeneREEP3chr10:64893260chr10:65369947ENST000003737584835_55139256.0TransmembraneHelical
TgeneREEP3chr10:64893260chr10:65369947ENST000003737584859_79139256.0TransmembraneHelical


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Fusion Gene Sequence for NRBF2-REEP3


check button For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. To have fusion amino acid sequence, we ran ORFfinder and chose the longest ORF among the all predicted ones.
>60204_60204_1_NRBF2-REEP3_NRBF2_chr10_64893260_ENST00000277746_REEP3_chr10_65354538_ENST00000298249_length(transcript)=5126nt_BP=211nt
CGCGGCGCGGCGCCGGAGGAGGAAGTGGTGAGGTTGTTGCTCCTTCAGCGCCTATCGCTGGCTCTTGGGGCGCAGAGAGGGGCCGCAGTC
TCCGCGGCTGCGTCGAGCTCCCTTGCAGTCCCCTCCATGTTCCCCGGCGCCACTACTCCCCTTCCTAAGGCCGCCGCTTACCCCGGGGTC
TATGGAAGTAATGGAAGGACCCCTCAACCTGGTTCGATGGATGATGTACTGGATTGTTTTTGCTCTCTATACTGTGATTGAAACAGTAGC
CGATCAAACAGTTGCTTGGTTTCCCCTGTACTATGAGCTGAAGATTGCTTTTGTCATATGGCTGCTTTCTCCCTATACCAAAGGAGCAAG
TTTAATATATAGAAAATTCCTTCATCCACTTCTTTCTTCAAAGGAAAGGGAGATTGATGATTATATTGTACAAGCAAAGGAACGAGGCTA
TGAAACCATGGTAAACTTTGGACGGCAAGGTTTAAACCTTGCAGCTACTGCTGCTGTTACTGCAGCAGTAAAGAGCCAAGGAGCAATAAC
TGAACGTTTAAGAAGCTTCAGTATGCATGATTTAACAACTATCCAAGGTGATGAGCCTGTGGGACAAAGACCATACCAACCTCTACCAGA
AGCAAAAAAGAAAAGTAAACCAGCCCCCAGTGAATCAGCAGGTTATGGAATTCCACTGAAAGACGGAGATGAGAAAACAGATGAAGAAGC
AGAGGGGCCATATTCAGATAATGAGATGTTAACACACAAAGGGCTTCGAAGATCGCAAAGCATGAAATCTGTGAAAACCACCAAAGGCCG
CAAAGAGGTGCGGTACGGGTCACTAAAATACAAAGTGAAGAAACGACCACAAGTGTATTTTTAGTCATCTACACGTCAAATATCCCAAGA
CAGATTATGCTAAATACATCGACTTCATCTTCTAACATGATATATTCAGGATTTACACATTAAAATGATTATTTAAATTGTGGCAGTGAT
GGGGTTTACTTTCATGAATTTAAATTGTTTTTATTTCTGTAACAATTGCTTCCAAATATTGACTACTAAAGGCAGTTCTGCAAGATGTAC
TAAATATGTATATTAGAAATTATAGAAAATCATGTTGTCCGTTTTCAAATTCATCAACAGCCTAGAGTGCCTGAGATATAAGATGAAACA
CAAATCCACAGTATACTTGAAAGGAGCCTTTTTACGGTTCAGGATAAATCAGCCTTTGTGATGTACTGTGTTTACCTCCTTTTGTGTTGT
ATCTGGTAATTAAATAGGCCTCAGATTCAGCAGTGACATAACAAGGACATAATGTAAGATAATAAAGTAGGTTTTATATATTCTTTAAAT
TTTTACTTATATAATACTTTCTAGTTTTTCCACCATCAGCTGAAAGTTTTTGAAACAAATATTTGAAAACCAGGTATCCACACATAGCAC
TTTTATTCCTGACTAGTTTTGCACACTTGAAAATTGTTTACTTATTTTACAACTGTTTTACTGATGCTATCTTTATTGTTTTTGCCGTAT
TCTGACATGTCAAATCTATGCCTTGAATTATATCATCTCTTTTCCTGTGGGTTTCATTTGTTAAATTCATTGGATTTTAATAATATAAAA
GTATAGCTAATTGTTCAGTTTTAACTATTTTTAATTATCTTCTTAACAAATAAGAAGTTGCTTTAAACATTAACCAATTTTCTATATTTA
GCTATACAGAGTAATTGAACTTAACATGTTTTTGTCAACACCAATTACATTTTCAGCTTTTAAAAATGGTAGCTTTTGTGAAATAGAATC
AGTGACCAGTATAGCACTTAGATCCCTTCTAACTCATATAATTTTTCTCAGCCAATCCATTCACAAGCTTGGCATTGACATGTGCTGCTA
GTTTATAAACTGGCATTGACGAAAATCATTTGAATCTCTTCTGGCTGAGATAATTTGCCAATGCAAAATACAGTTGTCATTAATCCTGCA
CATTAGAAATTATTAGAAACATATTACTTTTTAACTTTAAATCTCAAAGAGATTTTGAGTTATTGAATTCTTAAGGCTTTCTTAGCTTGA
ACTGATAACTATGCATTATGAACCCTAAGTCAATATATTTTTGGTGGTTTTAGTGATCAGTAATCAAATTTGTACTTATTATGCTTGTTC
AGGTAATTTACTTGACTGTTCTATTTGTTTGTCCAAAAGATAAAATGATGAGAGAGATTCGAGAGGTCTTTGATCTGTCTCCCTTTTAAG
AAATGAAGCCAGCTGGTAATGTATATTCAGGACTTCCTCAGAGTATTGGCCAAGAACATAATGTTTACACAGGAGTACCTTGGTATAATG
CATACATTGTCTCATGATACTAGTCATAAAATATTTTATGGATTATTTCACATTCTTCATATATAACAAGTAAAATTAATTCAGTTTTCT
TCTCCCAACGTTTAATTCTGAATAACTCTATCTACTTTACCCTAATTTTTAGCCTCTTAATTTCTGGAAGGACTCTAATTTCTATTCCAA
ATTTCTATGAATTCTAATTGTAAATTATCGGAACAGAGTTTTATTTATATGACCTGGTACTAGACTTCTTAATATAACTGTTACACTGTC
CTTGTCTTTCCTACTCAAAGACAGTATCATCTGAAGTTGCCTAATAAGGTCATGTGAGTCAAGAACTTTATCTGTGGGAGCTGATTTGCA
CCATTTTACCTTTTTTTTTTTTTTTTTTTTGAGACGGAGTCTTGCTCTGTCACCAGGCTGGAGTGCAGTGGCGCGATCTCGGCTCACTAC
AACCTCTGCCTCCCGGGTTCGAGCGATTCTCCTGCCTCGGCCTCCCGAGTAACTGGGTCTACAGGCCCGTGCTACCACGCCCAGCTAATT
TTTGTCTTTTTAGTAGAGACAGGGTTTAACCATGTTGCCCAGGATGGTCTCCATCTCTTGACCTCGTGATCCGCCCGCCTCGGCCTCCCA
AACTTCTGGGATTACAGGCGTGAGCCACCGCACCCAGCCACCATTTTATCTCTCTAAAGTCTGGTCCCAGTATTAAACCTATTCTTTAGT
AAACTCATATTACTGTTCTAAATTGAAGAAATTATTTATTACTCTGTACTTCTAGACTCAAAATTCTTTATCAAAGATAGTCTCAAAGAG
GTAGTACAAGTCCTGTTTAACTGCACTTTTTCACATTCACAGTGCTTCCTCTGATATCTTTCCTTACATCATTATACACTGTTGATATCA
TTTTACTCTTCTTTCTCTTCTACATTTCTTAAATTTTGGTTCTTTTCCTGTACATGTGTTTTAGCGGGGCCCTTTTCTTTGAACTTTGTC
TAATTAGCCTGTACATTTTTGTTTCTTTTAAGGTAGAACAGATCTTTTTTTGTTTCTCCTTTTAAGTCTACTGGTTTTAAAAGAGGTAAA
TGTATCCATAGACCACAGTGCCTTGCTTTTTCCTCTGCCAGCACATGGAGCACGGGATTAGATGCACAAACCTATTTAGGGAACTATTTT
GGTAGATGTTTGAGTTTATACAGAAATTGCAGCTGGTATTTTATTTTGCTGTACATTTACTCAACTTGTCCATTAGTATTTAACTATTTC
CAGAGTTTGTTTAGGAGTAAGAATTGACCCATTCGTTAGTTTACCATATTTTTTCCTGGTATAAAAAGGAGCCAGAAATAAGCCTTATTG
CTAAATAATTAATTATGTAAGCCCACCTAGGTCCTGCATAAGATCCCCCTCACATACTTCACAATATATATGTGTGTGTGTGTGTGTGTG
TGTGTGTGTGTGTGTGTGTGTGTATTTGGCTAAAAAATTATACTGCCAAAATTACTGATTATAAATACTTGACTACACTGATTGATGGGA
CAAAATGATTAAAGTATTTTCAGGGATCTTATTCCATATGTCACCACCAAAGATTTCTACAGTGTTATAAAGTATATAAATATTCCAAAT
TTCTGTGGTTAAATATTTTTTTCTTTTTTTTCCTTTTTTAGAATAACACAGTCTGTGCTTTCCAAAAATGCTTGAACTTTTATGTTGTTA
AGAAATATATAATGATATCTTACATTAAGCATGAGTCTAATTTGTATTAATTGGGATGGACTAAATTTTCATTTGATTATCAGGAAAATT
AAGGAGTTATATATTTAAAAGCAATTTTCTGTGTTTTCTTCTTTGTAAGTTGACTCATTTGTGAAGCAATTAGGCAAATTTTGAGAAGAT
CATTGTTATTGTGGTTTGCAGTATATATTTCTTAGTAAATATCACTTAAGATTAAATTTTTCAGAAAGAAAATTATAGCTTTTTTCCCAA
AATATTTTTAAGATTTAATCTTTTTGTAGTATGCTACAGATTTAATTATATTAACTCTTTTTTAAGACATTGACCATGACTTAACATTTT
GCCTTCTAACACCTTTTAAATCTATGTACTTTAATAGTTAAGAGAAAATAAGTTTGCAGATTTTTAATAATCTGTTTGTAAAAGGCTATC
TCTAAGCCTAGTATGTGGGTAATTTTACAGGTGTGTTTTTTGATAACTTTAATATAAAATAAACTCATTTTATTTGTGGCAATTCGCGTT
TCTTTTTTTATGCCAGAGTACATATGTTGGATTCCATGAATTGGTATTACTTATTATTATGTGTTGATTAAATATATGCACACACTTAGG
ATTACAGATCACAGAGCAAATTATGAAAATCATAAACATTCTGGTATGGTCATCCATAGGATTATGAAAAAGAAATACTGAATTGTTAAA
TTTGGATGTTAGAAAGGAAAGATAGGAAAAACAATGAGTACAGAAATCCTCACCATCAATTTGGATGGGTTAGCTGTCTCAGGCATAAAA
TGTAACACAAAATTCAGATTTATGTATCCTGGAAATGTTCTGGGGTTCCATCTGTTTTAAAGTTAGACGTCTGTCTGCCTCACATTTAAG
CTTTAGAGAGAAATCCTATGTTTTAAGAAGTTTCTTTGTGTTACTTCATTATGACACATAATGCGTGTTAAGGTCTTTCTAGATAGCATT

>60204_60204_1_NRBF2-REEP3_NRBF2_chr10_64893260_ENST00000277746_REEP3_chr10_65354538_ENST00000298249_length(amino acids)=269AA_BP=1
MGRREGPQSPRLRRAPLQSPPCSPAPLLPFLRPPLTPGSMEVMEGPLNLVRWMMYWIVFALYTVIETVADQTVAWFPLYYELKIAFVIWL
LSPYTKGASLIYRKFLHPLLSSKEREIDDYIVQAKERGYETMVNFGRQGLNLAATAAVTAAVKSQGAITERLRSFSMHDLTTIQGDEPVG

--------------------------------------------------------------
>60204_60204_2_NRBF2-REEP3_NRBF2_chr10_64893260_ENST00000277746_REEP3_chr10_65354538_ENST00000373758_length(transcript)=5128nt_BP=211nt
CGCGGCGCGGCGCCGGAGGAGGAAGTGGTGAGGTTGTTGCTCCTTCAGCGCCTATCGCTGGCTCTTGGGGCGCAGAGAGGGGCCGCAGTC
TCCGCGGCTGCGTCGAGCTCCCTTGCAGTCCCCTCCATGTTCCCCGGCGCCACTACTCCCCTTCCTAAGGCCGCCGCTTACCCCGGGGTC
TATGGAAGTAATGGAAGGACCCCTCAACCTGGTTCGATGGATGATGTACTGGATTGTTTTTGCTCTCTATACTGTGATTGAAACAGTAGC
CGATCAAACAGTTGCTTGGTTTCCCCTGTACTATGAGCTGAAGATTGCTTTTGTCATATGGCTGCTTTCTCCCTATACCAAAGGAGCAAG
TTTAATATATAGAAAATTCCTTCATCCACTTCTTTCTTCAAAGGAAAGGGAGATTGATGATTATATTGTACAAGCAAAGGAACGAGGCTA
TGAAACCATGGTAAACTTTGGACGGCAAGGTTTAAACCTTGCAGCTACTGCTGCTGTTACTGCAGCAGTAAAGAGCCAAGGAGCAATAAC
TGAACGTTTAAGAAGCTTCAGTATGCATGATTTAACAACTATCCAAGGTGATGAGCCTGTGGGACAAAGACCATACCAACCTCTACCAGA
AGCAAAAAAGAAAAGTAAACCAGCCCCCAGTGAATCAGCAGGTTATGGAATTCCACTGAAAGACGGAGATGAGAAAACAGATGAAGAAGC
AGAGGGGCCATATTCAGATAATGAGATGTTAACACACAAAGGGCTTCGAAGATCGCAAAGCATGAAATCTGTGAAAACCACCAAAGGCCG
CAAAGAGGTGCGGTACGGGTCACTAAAATACAAAGTGAAGAAACGACCACAAGTGTATTTTTAGTCATCTACACGTCAAATATCCCAAGA
CAGATTATGCTAAATACATCGACTTCATCTTCTAACATGATATATTCAGGATTTACACATTAAAATGATTATTTAAATTGTGGCAGTGAT
GGGGTTTACTTTCATGAATTTAAATTGTTTTTATTTCTGTAACAATTGCTTCCAAATATTGACTACTAAAGGCAGTTCTGCAAGATGTAC
TAAATATGTATATTAGAAATTATAGAAAATCATGTTGTCCGTTTTCAAATTCATCAACAGCCTAGAGTGCCTGAGATATAAGATGAAACA
CAAATCCACAGTATACTTGAAAGGAGCCTTTTTACGGTTCAGGATAAATCAGCCTTTGTGATGTACTGTGTTTACCTCCTTTTGTGTTGT
ATCTGGTAATTAAATAGGCCTCAGATTCAGCAGTGACATAACAAGGACATAATGTAAGATAATAAAGTAGGTTTTATATATTCTTTAAAT
TTTTACTTATATAATACTTTCTAGTTTTTCCACCATCAGCTGAAAGTTTTTGAAACAAATATTTGAAAACCAGGTATCCACACATAGCAC
TTTTATTCCTGACTAGTTTTGCACACTTGAAAATTGTTTACTTATTTTACAACTGTTTTACTGATGCTATCTTTATTGTTTTTGCCGTAT
TCTGACATGTCAAATCTATGCCTTGAATTATATCATCTCTTTTCCTGTGGGTTTCATTTGTTAAATTCATTGGATTTTAATAATATAAAA
GTATAGCTAATTGTTCAGTTTTAACTATTTTTAATTATCTTCTTAACAAATAAGAAGTTGCTTTAAACATTAACCAATTTTCTATATTTA
GCTATACAGAGTAATTGAACTTAACATGTTTTTGTCAACACCAATTACATTTTCAGCTTTTAAAAATGGTAGCTTTTGTGAAATAGAATC
AGTGACCAGTATAGCACTTAGATCCCTTCTAACTCATATAATTTTTCTCAGCCAATCCATTCACAAGCTTGGCATTGACATGTGCTGCTA
GTTTATAAACTGGCATTGACGAAAATCATTTGAATCTCTTCTGGCTGAGATAATTTGCCAATGCAAAATACAGTTGTCATTAATCCTGCA
CATTAGAAATTATTAGAAACATATTACTTTTTAACTTTAAATCTCAAAGAGATTTTGAGTTATTGAATTCTTAAGGCTTTCTTAGCTTGA
ACTGATAACTATGCATTATGAACCCTAAGTCAATATATTTTTGGTGGTTTTAGTGATCAGTAATCAAATTTGTACTTATTATGCTTGTTC
AGGTAATTTACTTGACTGTTCTATTTGTTTGTCCAAAAGATAAAATGATGAGAGAGATTCGAGAGGTCTTTGATCTGTCTCCCTTTTAAG
AAATGAAGCCAGCTGGTAATGTATATTCAGGACTTCCTCAGAGTATTGGCCAAGAACATAATGTTTACACAGGAGTACCTTGGTATAATG
CATACATTGTCTCATGATACTAGTCATAAAATATTTTATGGATTATTTCACATTCTTCATATATAACAAGTAAAATTAATTCAGTTTTCT
TCTCCCAACGTTTAATTCTGAATAACTCTATCTACTTTACCCTAATTTTTAGCCTCTTAATTTCTGGAAGGACTCTAATTTCTATTCCAA
ATTTCTATGAATTCTAATTGTAAATTATCGGAACAGAGTTTTATTTATATGACCTGGTACTAGACTTCTTAATATAACTGTTACACTGTC
CTTGTCTTTCCTACTCAAAGACAGTATCATCTGAAGTTGCCTAATAAGGTCATGTGAGTCAAGAACTTTATCTGTGGGAGCTGATTTGCA
CCATTTTACCTTTTTTTTTTTTTTTTTTTTGAGACGGAGTCTTGCTCTGTCACCAGGCTGGAGTGCAGTGGCGCGATCTCGGCTCACTAC
AACCTCTGCCTCCCGGGTTCGAGCGATTCTCCTGCCTCGGCCTCCCGAGTAACTGGGTCTACAGGCCCGTGCTACCACGCCCAGCTAATT
TTTGTCTTTTTAGTAGAGACAGGGTTTAACCATGTTGCCCAGGATGGTCTCCATCTCTTGACCTCGTGATCCGCCCGCCTCGGCCTCCCA
AACTTCTGGGATTACAGGCGTGAGCCACCGCACCCAGCCACCATTTTATCTCTCTAAAGTCTGGTCCCAGTATTAAACCTATTCTTTAGT
AAACTCATATTACTGTTCTAAATTGAAGAAATTATTTATTACTCTGTACTTCTAGACTCAAAATTCTTTATCAAAGATAGTCTCAAAGAG
GTAGTACAAGTCCTGTTTAACTGCACTTTTTCACATTCACAGTGCTTCCTCTGATATCTTTCCTTACATCATTATACACTGTTGATATCA
TTTTACTCTTCTTTCTCTTCTACATTTCTTAAATTTTGGTTCTTTTCCTGTACATGTGTTTTAGCGGGGCCCTTTTCTTTGAACTTTGTC
TAATTAGCCTGTACATTTTTGTTTCTTTTAAGGTAGAACAGATCTTTTTTTGTTTCTCCTTTTAAGTCTACTGGTTTTAAAAGAGGTAAA
TGTATCCATAGACCACAGTGCCTTGCTTTTTCCTCTGCCAGCACATGGAGCACGGGATTAGATGCACAAACCTATTTAGGGAACTATTTT
GGTAGATGTTTGAGTTTATACAGAAATTGCAGCTGGTATTTTATTTTGCTGTACATTTACTCAACTTGTCCATTAGTATTTAACTATTTC
CAGAGTTTGTTTAGGAGTAAGAATTGACCCATTCGTTAGTTTACCATATTTTTTCCTGGTATAAAAAGGAGCCAGAAATAAGCCTTATTG
CTAAATAATTAATTATGTAAGCCCACCTAGGTCCTGCATAAGATCCCCCTCACATACTTCACAATATATATGTGTGTGTGTGTGTGTGTG
TGTGTGTGTGTGTGTGTGTGTGTATTTGGCTAAAAAATTATACTGCCAAAATTACTGATTATAAATACTTGACTACACTGATTGATGGGA
CAAAATGATTAAAGTATTTTCAGGGATCTTATTCCATATGTCACCACCAAAGATTTCTACAGTGTTATAAAGTATATAAATATTCCAAAT
TTCTGTGGTTAAATATTTTTTTCTTTTTTTTCCTTTTTTAGAATAACACAGTCTGTGCTTTCCAAAAATGCTTGAACTTTTATGTTGTTA
AGAAATATATAATGATATCTTACATTAAGCATGAGTCTAATTTGTATTAATTGGGATGGACTAAATTTTCATTTGATTATCAGGAAAATT
AAGGAGTTATATATTTAAAAGCAATTTTCTGTGTTTTCTTCTTTGTAAGTTGACTCATTTGTGAAGCAATTAGGCAAATTTTGAGAAGAT
CATTGTTATTGTGGTTTGCAGTATATATTTCTTAGTAAATATCACTTAAGATTAAATTTTTCAGAAAGAAAATTATAGCTTTTTTCCCAA
AATATTTTTAAGATTTAATCTTTTTGTAGTATGCTACAGATTTAATTATATTAACTCTTTTTTAAGACATTGACCATGACTTAACATTTT
GCCTTCTAACACCTTTTAAATCTATGTACTTTAATAGTTAAGAGAAAATAAGTTTGCAGATTTTTAATAATCTGTTTGTAAAAGGCTATC
TCTAAGCCTAGTATGTGGGTAATTTTACAGGTGTGTTTTTTGATAACTTTAATATAAAATAAACTCATTTTATTTGTGGCAATTCGCGTT
TCTTTTTTTATGCCAGAGTACATATGTTGGATTCCATGAATTGGTATTACTTATTATTATGTGTTGATTAAATATATGCACACACTTAGG
ATTACAGATCACAGAGCAAATTATGAAAATCATAAACATTCTGGTATGGTCATCCATAGGATTATGAAAAAGAAATACTGAATTGTTAAA
TTTGGATGTTAGAAAGGAAAGATAGGAAAAACAATGAGTACAGAAATCCTCACCATCAATTTGGATGGGTTAGCTGTCTCAGGCATAAAA
TGTAACACAAAATTCAGATTTATGTATCCTGGAAATGTTCTGGGGTTCCATCTGTTTTAAAGTTAGACGTCTGTCTGCCTCACATTTAAG
CTTTAGAGAGAAATCCTATGTTTTAAGAAGTTTCTTTGTGTTACTTCATTATGACACATAATGCGTGTTAAGGTCTTTCTAGATAGCATT

>60204_60204_2_NRBF2-REEP3_NRBF2_chr10_64893260_ENST00000277746_REEP3_chr10_65354538_ENST00000373758_length(amino acids)=269AA_BP=1
MGRREGPQSPRLRRAPLQSPPCSPAPLLPFLRPPLTPGSMEVMEGPLNLVRWMMYWIVFALYTVIETVADQTVAWFPLYYELKIAFVIWL
LSPYTKGASLIYRKFLHPLLSSKEREIDDYIVQAKERGYETMVNFGRQGLNLAATAAVTAAVKSQGAITERLRSFSMHDLTTIQGDEPVG

--------------------------------------------------------------
>60204_60204_3_NRBF2-REEP3_NRBF2_chr10_64893260_ENST00000277746_REEP3_chr10_65369946_ENST00000298249_length(transcript)=4814nt_BP=211nt
CGCGGCGCGGCGCCGGAGGAGGAAGTGGTGAGGTTGTTGCTCCTTCAGCGCCTATCGCTGGCTCTTGGGGCGCAGAGAGGGGCCGCAGTC
TCCGCGGCTGCGTCGAGCTCCCTTGCAGTCCCCTCCATGTTCCCCGGCGCCACTACTCCCCTTCCTAAGGCCGCCGCTTACCCCGGGGTC
TATGGAAGTAATGGAAGGACCCCTCAACCTGAGCCAAGGAGCAATAACTGAACGTTTAAGAAGCTTCAGTATGCATGATTTAACAACTAT
CCAAGGTGATGAGCCTGTGGGACAAAGACCATACCAACCTCTACCAGAAGCAAAAAAGAAAAGTAAACCAGCCCCCAGTGAATCAGCAGG
TTATGGAATTCCACTGAAAGACGGAGATGAGAAAACAGATGAAGAAGCAGAGGGGCCATATTCAGATAATGAGATGTTAACACACAAAGG
GCTTCGAAGATCGCAAAGCATGAAATCTGTGAAAACCACCAAAGGCCGCAAAGAGGTGCGGTACGGGTCACTAAAATACAAAGTGAAGAA
ACGACCACAAGTGTATTTTTAGTCATCTACACGTCAAATATCCCAAGACAGATTATGCTAAATACATCGACTTCATCTTCTAACATGATA
TATTCAGGATTTACACATTAAAATGATTATTTAAATTGTGGCAGTGATGGGGTTTACTTTCATGAATTTAAATTGTTTTTATTTCTGTAA
CAATTGCTTCCAAATATTGACTACTAAAGGCAGTTCTGCAAGATGTACTAAATATGTATATTAGAAATTATAGAAAATCATGTTGTCCGT
TTTCAAATTCATCAACAGCCTAGAGTGCCTGAGATATAAGATGAAACACAAATCCACAGTATACTTGAAAGGAGCCTTTTTACGGTTCAG
GATAAATCAGCCTTTGTGATGTACTGTGTTTACCTCCTTTTGTGTTGTATCTGGTAATTAAATAGGCCTCAGATTCAGCAGTGACATAAC
AAGGACATAATGTAAGATAATAAAGTAGGTTTTATATATTCTTTAAATTTTTACTTATATAATACTTTCTAGTTTTTCCACCATCAGCTG
AAAGTTTTTGAAACAAATATTTGAAAACCAGGTATCCACACATAGCACTTTTATTCCTGACTAGTTTTGCACACTTGAAAATTGTTTACT
TATTTTACAACTGTTTTACTGATGCTATCTTTATTGTTTTTGCCGTATTCTGACATGTCAAATCTATGCCTTGAATTATATCATCTCTTT
TCCTGTGGGTTTCATTTGTTAAATTCATTGGATTTTAATAATATAAAAGTATAGCTAATTGTTCAGTTTTAACTATTTTTAATTATCTTC
TTAACAAATAAGAAGTTGCTTTAAACATTAACCAATTTTCTATATTTAGCTATACAGAGTAATTGAACTTAACATGTTTTTGTCAACACC
AATTACATTTTCAGCTTTTAAAAATGGTAGCTTTTGTGAAATAGAATCAGTGACCAGTATAGCACTTAGATCCCTTCTAACTCATATAAT
TTTTCTCAGCCAATCCATTCACAAGCTTGGCATTGACATGTGCTGCTAGTTTATAAACTGGCATTGACGAAAATCATTTGAATCTCTTCT
GGCTGAGATAATTTGCCAATGCAAAATACAGTTGTCATTAATCCTGCACATTAGAAATTATTAGAAACATATTACTTTTTAACTTTAAAT
CTCAAAGAGATTTTGAGTTATTGAATTCTTAAGGCTTTCTTAGCTTGAACTGATAACTATGCATTATGAACCCTAAGTCAATATATTTTT
GGTGGTTTTAGTGATCAGTAATCAAATTTGTACTTATTATGCTTGTTCAGGTAATTTACTTGACTGTTCTATTTGTTTGTCCAAAAGATA
AAATGATGAGAGAGATTCGAGAGGTCTTTGATCTGTCTCCCTTTTAAGAAATGAAGCCAGCTGGTAATGTATATTCAGGACTTCCTCAGA
GTATTGGCCAAGAACATAATGTTTACACAGGAGTACCTTGGTATAATGCATACATTGTCTCATGATACTAGTCATAAAATATTTTATGGA
TTATTTCACATTCTTCATATATAACAAGTAAAATTAATTCAGTTTTCTTCTCCCAACGTTTAATTCTGAATAACTCTATCTACTTTACCC
TAATTTTTAGCCTCTTAATTTCTGGAAGGACTCTAATTTCTATTCCAAATTTCTATGAATTCTAATTGTAAATTATCGGAACAGAGTTTT
ATTTATATGACCTGGTACTAGACTTCTTAATATAACTGTTACACTGTCCTTGTCTTTCCTACTCAAAGACAGTATCATCTGAAGTTGCCT
AATAAGGTCATGTGAGTCAAGAACTTTATCTGTGGGAGCTGATTTGCACCATTTTACCTTTTTTTTTTTTTTTTTTTTGAGACGGAGTCT
TGCTCTGTCACCAGGCTGGAGTGCAGTGGCGCGATCTCGGCTCACTACAACCTCTGCCTCCCGGGTTCGAGCGATTCTCCTGCCTCGGCC
TCCCGAGTAACTGGGTCTACAGGCCCGTGCTACCACGCCCAGCTAATTTTTGTCTTTTTAGTAGAGACAGGGTTTAACCATGTTGCCCAG
GATGGTCTCCATCTCTTGACCTCGTGATCCGCCCGCCTCGGCCTCCCAAACTTCTGGGATTACAGGCGTGAGCCACCGCACCCAGCCACC
ATTTTATCTCTCTAAAGTCTGGTCCCAGTATTAAACCTATTCTTTAGTAAACTCATATTACTGTTCTAAATTGAAGAAATTATTTATTAC
TCTGTACTTCTAGACTCAAAATTCTTTATCAAAGATAGTCTCAAAGAGGTAGTACAAGTCCTGTTTAACTGCACTTTTTCACATTCACAG
TGCTTCCTCTGATATCTTTCCTTACATCATTATACACTGTTGATATCATTTTACTCTTCTTTCTCTTCTACATTTCTTAAATTTTGGTTC
TTTTCCTGTACATGTGTTTTAGCGGGGCCCTTTTCTTTGAACTTTGTCTAATTAGCCTGTACATTTTTGTTTCTTTTAAGGTAGAACAGA
TCTTTTTTTGTTTCTCCTTTTAAGTCTACTGGTTTTAAAAGAGGTAAATGTATCCATAGACCACAGTGCCTTGCTTTTTCCTCTGCCAGC
ACATGGAGCACGGGATTAGATGCACAAACCTATTTAGGGAACTATTTTGGTAGATGTTTGAGTTTATACAGAAATTGCAGCTGGTATTTT
ATTTTGCTGTACATTTACTCAACTTGTCCATTAGTATTTAACTATTTCCAGAGTTTGTTTAGGAGTAAGAATTGACCCATTCGTTAGTTT
ACCATATTTTTTCCTGGTATAAAAAGGAGCCAGAAATAAGCCTTATTGCTAAATAATTAATTATGTAAGCCCACCTAGGTCCTGCATAAG
ATCCCCCTCACATACTTCACAATATATATGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTATTTGGCTAAAAAATTATA
CTGCCAAAATTACTGATTATAAATACTTGACTACACTGATTGATGGGACAAAATGATTAAAGTATTTTCAGGGATCTTATTCCATATGTC
ACCACCAAAGATTTCTACAGTGTTATAAAGTATATAAATATTCCAAATTTCTGTGGTTAAATATTTTTTTCTTTTTTTTCCTTTTTTAGA
ATAACACAGTCTGTGCTTTCCAAAAATGCTTGAACTTTTATGTTGTTAAGAAATATATAATGATATCTTACATTAAGCATGAGTCTAATT
TGTATTAATTGGGATGGACTAAATTTTCATTTGATTATCAGGAAAATTAAGGAGTTATATATTTAAAAGCAATTTTCTGTGTTTTCTTCT
TTGTAAGTTGACTCATTTGTGAAGCAATTAGGCAAATTTTGAGAAGATCATTGTTATTGTGGTTTGCAGTATATATTTCTTAGTAAATAT
CACTTAAGATTAAATTTTTCAGAAAGAAAATTATAGCTTTTTTCCCAAAATATTTTTAAGATTTAATCTTTTTGTAGTATGCTACAGATT
TAATTATATTAACTCTTTTTTAAGACATTGACCATGACTTAACATTTTGCCTTCTAACACCTTTTAAATCTATGTACTTTAATAGTTAAG
AGAAAATAAGTTTGCAGATTTTTAATAATCTGTTTGTAAAAGGCTATCTCTAAGCCTAGTATGTGGGTAATTTTACAGGTGTGTTTTTTG
ATAACTTTAATATAAAATAAACTCATTTTATTTGTGGCAATTCGCGTTTCTTTTTTTATGCCAGAGTACATATGTTGGATTCCATGAATT
GGTATTACTTATTATTATGTGTTGATTAAATATATGCACACACTTAGGATTACAGATCACAGAGCAAATTATGAAAATCATAAACATTCT
GGTATGGTCATCCATAGGATTATGAAAAAGAAATACTGAATTGTTAAATTTGGATGTTAGAAAGGAAAGATAGGAAAAACAATGAGTACA
GAAATCCTCACCATCAATTTGGATGGGTTAGCTGTCTCAGGCATAAAATGTAACACAAAATTCAGATTTATGTATCCTGGAAATGTTCTG
GGGTTCCATCTGTTTTAAAGTTAGACGTCTGTCTGCCTCACATTTAAGCTTTAGAGAGAAATCCTATGTTTTAAGAAGTTTCTTTGTGTT
ACTTCATTATGACACATAATGCGTGTTAAGGTCTTTCTAGATAGCATTTTAAATGGAATTATTTTCATTTTCATTATGAGGTATATACTT

>60204_60204_3_NRBF2-REEP3_NRBF2_chr10_64893260_ENST00000277746_REEP3_chr10_65369946_ENST00000298249_length(amino acids)=165AA_BP=1
MGRREGPQSPRLRRAPLQSPPCSPAPLLPFLRPPLTPGSMEVMEGPLNLSQGAITERLRSFSMHDLTTIQGDEPVGQRPYQPLPEAKKKS

--------------------------------------------------------------
>60204_60204_4_NRBF2-REEP3_NRBF2_chr10_64893260_ENST00000277746_REEP3_chr10_65369946_ENST00000373758_length(transcript)=4816nt_BP=211nt
CGCGGCGCGGCGCCGGAGGAGGAAGTGGTGAGGTTGTTGCTCCTTCAGCGCCTATCGCTGGCTCTTGGGGCGCAGAGAGGGGCCGCAGTC
TCCGCGGCTGCGTCGAGCTCCCTTGCAGTCCCCTCCATGTTCCCCGGCGCCACTACTCCCCTTCCTAAGGCCGCCGCTTACCCCGGGGTC
TATGGAAGTAATGGAAGGACCCCTCAACCTGAGCCAAGGAGCAATAACTGAACGTTTAAGAAGCTTCAGTATGCATGATTTAACAACTAT
CCAAGGTGATGAGCCTGTGGGACAAAGACCATACCAACCTCTACCAGAAGCAAAAAAGAAAAGTAAACCAGCCCCCAGTGAATCAGCAGG
TTATGGAATTCCACTGAAAGACGGAGATGAGAAAACAGATGAAGAAGCAGAGGGGCCATATTCAGATAATGAGATGTTAACACACAAAGG
GCTTCGAAGATCGCAAAGCATGAAATCTGTGAAAACCACCAAAGGCCGCAAAGAGGTGCGGTACGGGTCACTAAAATACAAAGTGAAGAA
ACGACCACAAGTGTATTTTTAGTCATCTACACGTCAAATATCCCAAGACAGATTATGCTAAATACATCGACTTCATCTTCTAACATGATA
TATTCAGGATTTACACATTAAAATGATTATTTAAATTGTGGCAGTGATGGGGTTTACTTTCATGAATTTAAATTGTTTTTATTTCTGTAA
CAATTGCTTCCAAATATTGACTACTAAAGGCAGTTCTGCAAGATGTACTAAATATGTATATTAGAAATTATAGAAAATCATGTTGTCCGT
TTTCAAATTCATCAACAGCCTAGAGTGCCTGAGATATAAGATGAAACACAAATCCACAGTATACTTGAAAGGAGCCTTTTTACGGTTCAG
GATAAATCAGCCTTTGTGATGTACTGTGTTTACCTCCTTTTGTGTTGTATCTGGTAATTAAATAGGCCTCAGATTCAGCAGTGACATAAC
AAGGACATAATGTAAGATAATAAAGTAGGTTTTATATATTCTTTAAATTTTTACTTATATAATACTTTCTAGTTTTTCCACCATCAGCTG
AAAGTTTTTGAAACAAATATTTGAAAACCAGGTATCCACACATAGCACTTTTATTCCTGACTAGTTTTGCACACTTGAAAATTGTTTACT
TATTTTACAACTGTTTTACTGATGCTATCTTTATTGTTTTTGCCGTATTCTGACATGTCAAATCTATGCCTTGAATTATATCATCTCTTT
TCCTGTGGGTTTCATTTGTTAAATTCATTGGATTTTAATAATATAAAAGTATAGCTAATTGTTCAGTTTTAACTATTTTTAATTATCTTC
TTAACAAATAAGAAGTTGCTTTAAACATTAACCAATTTTCTATATTTAGCTATACAGAGTAATTGAACTTAACATGTTTTTGTCAACACC
AATTACATTTTCAGCTTTTAAAAATGGTAGCTTTTGTGAAATAGAATCAGTGACCAGTATAGCACTTAGATCCCTTCTAACTCATATAAT
TTTTCTCAGCCAATCCATTCACAAGCTTGGCATTGACATGTGCTGCTAGTTTATAAACTGGCATTGACGAAAATCATTTGAATCTCTTCT
GGCTGAGATAATTTGCCAATGCAAAATACAGTTGTCATTAATCCTGCACATTAGAAATTATTAGAAACATATTACTTTTTAACTTTAAAT
CTCAAAGAGATTTTGAGTTATTGAATTCTTAAGGCTTTCTTAGCTTGAACTGATAACTATGCATTATGAACCCTAAGTCAATATATTTTT
GGTGGTTTTAGTGATCAGTAATCAAATTTGTACTTATTATGCTTGTTCAGGTAATTTACTTGACTGTTCTATTTGTTTGTCCAAAAGATA
AAATGATGAGAGAGATTCGAGAGGTCTTTGATCTGTCTCCCTTTTAAGAAATGAAGCCAGCTGGTAATGTATATTCAGGACTTCCTCAGA
GTATTGGCCAAGAACATAATGTTTACACAGGAGTACCTTGGTATAATGCATACATTGTCTCATGATACTAGTCATAAAATATTTTATGGA
TTATTTCACATTCTTCATATATAACAAGTAAAATTAATTCAGTTTTCTTCTCCCAACGTTTAATTCTGAATAACTCTATCTACTTTACCC
TAATTTTTAGCCTCTTAATTTCTGGAAGGACTCTAATTTCTATTCCAAATTTCTATGAATTCTAATTGTAAATTATCGGAACAGAGTTTT
ATTTATATGACCTGGTACTAGACTTCTTAATATAACTGTTACACTGTCCTTGTCTTTCCTACTCAAAGACAGTATCATCTGAAGTTGCCT
AATAAGGTCATGTGAGTCAAGAACTTTATCTGTGGGAGCTGATTTGCACCATTTTACCTTTTTTTTTTTTTTTTTTTTGAGACGGAGTCT
TGCTCTGTCACCAGGCTGGAGTGCAGTGGCGCGATCTCGGCTCACTACAACCTCTGCCTCCCGGGTTCGAGCGATTCTCCTGCCTCGGCC
TCCCGAGTAACTGGGTCTACAGGCCCGTGCTACCACGCCCAGCTAATTTTTGTCTTTTTAGTAGAGACAGGGTTTAACCATGTTGCCCAG
GATGGTCTCCATCTCTTGACCTCGTGATCCGCCCGCCTCGGCCTCCCAAACTTCTGGGATTACAGGCGTGAGCCACCGCACCCAGCCACC
ATTTTATCTCTCTAAAGTCTGGTCCCAGTATTAAACCTATTCTTTAGTAAACTCATATTACTGTTCTAAATTGAAGAAATTATTTATTAC
TCTGTACTTCTAGACTCAAAATTCTTTATCAAAGATAGTCTCAAAGAGGTAGTACAAGTCCTGTTTAACTGCACTTTTTCACATTCACAG
TGCTTCCTCTGATATCTTTCCTTACATCATTATACACTGTTGATATCATTTTACTCTTCTTTCTCTTCTACATTTCTTAAATTTTGGTTC
TTTTCCTGTACATGTGTTTTAGCGGGGCCCTTTTCTTTGAACTTTGTCTAATTAGCCTGTACATTTTTGTTTCTTTTAAGGTAGAACAGA
TCTTTTTTTGTTTCTCCTTTTAAGTCTACTGGTTTTAAAAGAGGTAAATGTATCCATAGACCACAGTGCCTTGCTTTTTCCTCTGCCAGC
ACATGGAGCACGGGATTAGATGCACAAACCTATTTAGGGAACTATTTTGGTAGATGTTTGAGTTTATACAGAAATTGCAGCTGGTATTTT
ATTTTGCTGTACATTTACTCAACTTGTCCATTAGTATTTAACTATTTCCAGAGTTTGTTTAGGAGTAAGAATTGACCCATTCGTTAGTTT
ACCATATTTTTTCCTGGTATAAAAAGGAGCCAGAAATAAGCCTTATTGCTAAATAATTAATTATGTAAGCCCACCTAGGTCCTGCATAAG
ATCCCCCTCACATACTTCACAATATATATGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTATTTGGCTAAAAAATTATA
CTGCCAAAATTACTGATTATAAATACTTGACTACACTGATTGATGGGACAAAATGATTAAAGTATTTTCAGGGATCTTATTCCATATGTC
ACCACCAAAGATTTCTACAGTGTTATAAAGTATATAAATATTCCAAATTTCTGTGGTTAAATATTTTTTTCTTTTTTTTCCTTTTTTAGA
ATAACACAGTCTGTGCTTTCCAAAAATGCTTGAACTTTTATGTTGTTAAGAAATATATAATGATATCTTACATTAAGCATGAGTCTAATT
TGTATTAATTGGGATGGACTAAATTTTCATTTGATTATCAGGAAAATTAAGGAGTTATATATTTAAAAGCAATTTTCTGTGTTTTCTTCT
TTGTAAGTTGACTCATTTGTGAAGCAATTAGGCAAATTTTGAGAAGATCATTGTTATTGTGGTTTGCAGTATATATTTCTTAGTAAATAT
CACTTAAGATTAAATTTTTCAGAAAGAAAATTATAGCTTTTTTCCCAAAATATTTTTAAGATTTAATCTTTTTGTAGTATGCTACAGATT
TAATTATATTAACTCTTTTTTAAGACATTGACCATGACTTAACATTTTGCCTTCTAACACCTTTTAAATCTATGTACTTTAATAGTTAAG
AGAAAATAAGTTTGCAGATTTTTAATAATCTGTTTGTAAAAGGCTATCTCTAAGCCTAGTATGTGGGTAATTTTACAGGTGTGTTTTTTG
ATAACTTTAATATAAAATAAACTCATTTTATTTGTGGCAATTCGCGTTTCTTTTTTTATGCCAGAGTACATATGTTGGATTCCATGAATT
GGTATTACTTATTATTATGTGTTGATTAAATATATGCACACACTTAGGATTACAGATCACAGAGCAAATTATGAAAATCATAAACATTCT
GGTATGGTCATCCATAGGATTATGAAAAAGAAATACTGAATTGTTAAATTTGGATGTTAGAAAGGAAAGATAGGAAAAACAATGAGTACA
GAAATCCTCACCATCAATTTGGATGGGTTAGCTGTCTCAGGCATAAAATGTAACACAAAATTCAGATTTATGTATCCTGGAAATGTTCTG
GGGTTCCATCTGTTTTAAAGTTAGACGTCTGTCTGCCTCACATTTAAGCTTTAGAGAGAAATCCTATGTTTTAAGAAGTTTCTTTGTGTT
ACTTCATTATGACACATAATGCGTGTTAAGGTCTTTCTAGATAGCATTTTAAATGGAATTATTTTCATTTTCATTATGAGGTATATACTT

>60204_60204_4_NRBF2-REEP3_NRBF2_chr10_64893260_ENST00000277746_REEP3_chr10_65369946_ENST00000373758_length(amino acids)=165AA_BP=1
MGRREGPQSPRLRRAPLQSPPCSPAPLLPFLRPPLTPGSMEVMEGPLNLSQGAITERLRSFSMHDLTTIQGDEPVGQRPYQPLPEAKKKS

--------------------------------------------------------------
>60204_60204_5_NRBF2-REEP3_NRBF2_chr10_64893260_ENST00000277746_REEP3_chr10_65369947_ENST00000298249_length(transcript)=4814nt_BP=211nt
CGCGGCGCGGCGCCGGAGGAGGAAGTGGTGAGGTTGTTGCTCCTTCAGCGCCTATCGCTGGCTCTTGGGGCGCAGAGAGGGGCCGCAGTC
TCCGCGGCTGCGTCGAGCTCCCTTGCAGTCCCCTCCATGTTCCCCGGCGCCACTACTCCCCTTCCTAAGGCCGCCGCTTACCCCGGGGTC
TATGGAAGTAATGGAAGGACCCCTCAACCTGAGCCAAGGAGCAATAACTGAACGTTTAAGAAGCTTCAGTATGCATGATTTAACAACTAT
CCAAGGTGATGAGCCTGTGGGACAAAGACCATACCAACCTCTACCAGAAGCAAAAAAGAAAAGTAAACCAGCCCCCAGTGAATCAGCAGG
TTATGGAATTCCACTGAAAGACGGAGATGAGAAAACAGATGAAGAAGCAGAGGGGCCATATTCAGATAATGAGATGTTAACACACAAAGG
GCTTCGAAGATCGCAAAGCATGAAATCTGTGAAAACCACCAAAGGCCGCAAAGAGGTGCGGTACGGGTCACTAAAATACAAAGTGAAGAA
ACGACCACAAGTGTATTTTTAGTCATCTACACGTCAAATATCCCAAGACAGATTATGCTAAATACATCGACTTCATCTTCTAACATGATA
TATTCAGGATTTACACATTAAAATGATTATTTAAATTGTGGCAGTGATGGGGTTTACTTTCATGAATTTAAATTGTTTTTATTTCTGTAA
CAATTGCTTCCAAATATTGACTACTAAAGGCAGTTCTGCAAGATGTACTAAATATGTATATTAGAAATTATAGAAAATCATGTTGTCCGT
TTTCAAATTCATCAACAGCCTAGAGTGCCTGAGATATAAGATGAAACACAAATCCACAGTATACTTGAAAGGAGCCTTTTTACGGTTCAG
GATAAATCAGCCTTTGTGATGTACTGTGTTTACCTCCTTTTGTGTTGTATCTGGTAATTAAATAGGCCTCAGATTCAGCAGTGACATAAC
AAGGACATAATGTAAGATAATAAAGTAGGTTTTATATATTCTTTAAATTTTTACTTATATAATACTTTCTAGTTTTTCCACCATCAGCTG
AAAGTTTTTGAAACAAATATTTGAAAACCAGGTATCCACACATAGCACTTTTATTCCTGACTAGTTTTGCACACTTGAAAATTGTTTACT
TATTTTACAACTGTTTTACTGATGCTATCTTTATTGTTTTTGCCGTATTCTGACATGTCAAATCTATGCCTTGAATTATATCATCTCTTT
TCCTGTGGGTTTCATTTGTTAAATTCATTGGATTTTAATAATATAAAAGTATAGCTAATTGTTCAGTTTTAACTATTTTTAATTATCTTC
TTAACAAATAAGAAGTTGCTTTAAACATTAACCAATTTTCTATATTTAGCTATACAGAGTAATTGAACTTAACATGTTTTTGTCAACACC
AATTACATTTTCAGCTTTTAAAAATGGTAGCTTTTGTGAAATAGAATCAGTGACCAGTATAGCACTTAGATCCCTTCTAACTCATATAAT
TTTTCTCAGCCAATCCATTCACAAGCTTGGCATTGACATGTGCTGCTAGTTTATAAACTGGCATTGACGAAAATCATTTGAATCTCTTCT
GGCTGAGATAATTTGCCAATGCAAAATACAGTTGTCATTAATCCTGCACATTAGAAATTATTAGAAACATATTACTTTTTAACTTTAAAT
CTCAAAGAGATTTTGAGTTATTGAATTCTTAAGGCTTTCTTAGCTTGAACTGATAACTATGCATTATGAACCCTAAGTCAATATATTTTT
GGTGGTTTTAGTGATCAGTAATCAAATTTGTACTTATTATGCTTGTTCAGGTAATTTACTTGACTGTTCTATTTGTTTGTCCAAAAGATA
AAATGATGAGAGAGATTCGAGAGGTCTTTGATCTGTCTCCCTTTTAAGAAATGAAGCCAGCTGGTAATGTATATTCAGGACTTCCTCAGA
GTATTGGCCAAGAACATAATGTTTACACAGGAGTACCTTGGTATAATGCATACATTGTCTCATGATACTAGTCATAAAATATTTTATGGA
TTATTTCACATTCTTCATATATAACAAGTAAAATTAATTCAGTTTTCTTCTCCCAACGTTTAATTCTGAATAACTCTATCTACTTTACCC
TAATTTTTAGCCTCTTAATTTCTGGAAGGACTCTAATTTCTATTCCAAATTTCTATGAATTCTAATTGTAAATTATCGGAACAGAGTTTT
ATTTATATGACCTGGTACTAGACTTCTTAATATAACTGTTACACTGTCCTTGTCTTTCCTACTCAAAGACAGTATCATCTGAAGTTGCCT
AATAAGGTCATGTGAGTCAAGAACTTTATCTGTGGGAGCTGATTTGCACCATTTTACCTTTTTTTTTTTTTTTTTTTTGAGACGGAGTCT
TGCTCTGTCACCAGGCTGGAGTGCAGTGGCGCGATCTCGGCTCACTACAACCTCTGCCTCCCGGGTTCGAGCGATTCTCCTGCCTCGGCC
TCCCGAGTAACTGGGTCTACAGGCCCGTGCTACCACGCCCAGCTAATTTTTGTCTTTTTAGTAGAGACAGGGTTTAACCATGTTGCCCAG
GATGGTCTCCATCTCTTGACCTCGTGATCCGCCCGCCTCGGCCTCCCAAACTTCTGGGATTACAGGCGTGAGCCACCGCACCCAGCCACC
ATTTTATCTCTCTAAAGTCTGGTCCCAGTATTAAACCTATTCTTTAGTAAACTCATATTACTGTTCTAAATTGAAGAAATTATTTATTAC
TCTGTACTTCTAGACTCAAAATTCTTTATCAAAGATAGTCTCAAAGAGGTAGTACAAGTCCTGTTTAACTGCACTTTTTCACATTCACAG
TGCTTCCTCTGATATCTTTCCTTACATCATTATACACTGTTGATATCATTTTACTCTTCTTTCTCTTCTACATTTCTTAAATTTTGGTTC
TTTTCCTGTACATGTGTTTTAGCGGGGCCCTTTTCTTTGAACTTTGTCTAATTAGCCTGTACATTTTTGTTTCTTTTAAGGTAGAACAGA
TCTTTTTTTGTTTCTCCTTTTAAGTCTACTGGTTTTAAAAGAGGTAAATGTATCCATAGACCACAGTGCCTTGCTTTTTCCTCTGCCAGC
ACATGGAGCACGGGATTAGATGCACAAACCTATTTAGGGAACTATTTTGGTAGATGTTTGAGTTTATACAGAAATTGCAGCTGGTATTTT
ATTTTGCTGTACATTTACTCAACTTGTCCATTAGTATTTAACTATTTCCAGAGTTTGTTTAGGAGTAAGAATTGACCCATTCGTTAGTTT
ACCATATTTTTTCCTGGTATAAAAAGGAGCCAGAAATAAGCCTTATTGCTAAATAATTAATTATGTAAGCCCACCTAGGTCCTGCATAAG
ATCCCCCTCACATACTTCACAATATATATGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTATTTGGCTAAAAAATTATA
CTGCCAAAATTACTGATTATAAATACTTGACTACACTGATTGATGGGACAAAATGATTAAAGTATTTTCAGGGATCTTATTCCATATGTC
ACCACCAAAGATTTCTACAGTGTTATAAAGTATATAAATATTCCAAATTTCTGTGGTTAAATATTTTTTTCTTTTTTTTCCTTTTTTAGA
ATAACACAGTCTGTGCTTTCCAAAAATGCTTGAACTTTTATGTTGTTAAGAAATATATAATGATATCTTACATTAAGCATGAGTCTAATT
TGTATTAATTGGGATGGACTAAATTTTCATTTGATTATCAGGAAAATTAAGGAGTTATATATTTAAAAGCAATTTTCTGTGTTTTCTTCT
TTGTAAGTTGACTCATTTGTGAAGCAATTAGGCAAATTTTGAGAAGATCATTGTTATTGTGGTTTGCAGTATATATTTCTTAGTAAATAT
CACTTAAGATTAAATTTTTCAGAAAGAAAATTATAGCTTTTTTCCCAAAATATTTTTAAGATTTAATCTTTTTGTAGTATGCTACAGATT
TAATTATATTAACTCTTTTTTAAGACATTGACCATGACTTAACATTTTGCCTTCTAACACCTTTTAAATCTATGTACTTTAATAGTTAAG
AGAAAATAAGTTTGCAGATTTTTAATAATCTGTTTGTAAAAGGCTATCTCTAAGCCTAGTATGTGGGTAATTTTACAGGTGTGTTTTTTG
ATAACTTTAATATAAAATAAACTCATTTTATTTGTGGCAATTCGCGTTTCTTTTTTTATGCCAGAGTACATATGTTGGATTCCATGAATT
GGTATTACTTATTATTATGTGTTGATTAAATATATGCACACACTTAGGATTACAGATCACAGAGCAAATTATGAAAATCATAAACATTCT
GGTATGGTCATCCATAGGATTATGAAAAAGAAATACTGAATTGTTAAATTTGGATGTTAGAAAGGAAAGATAGGAAAAACAATGAGTACA
GAAATCCTCACCATCAATTTGGATGGGTTAGCTGTCTCAGGCATAAAATGTAACACAAAATTCAGATTTATGTATCCTGGAAATGTTCTG
GGGTTCCATCTGTTTTAAAGTTAGACGTCTGTCTGCCTCACATTTAAGCTTTAGAGAGAAATCCTATGTTTTAAGAAGTTTCTTTGTGTT
ACTTCATTATGACACATAATGCGTGTTAAGGTCTTTCTAGATAGCATTTTAAATGGAATTATTTTCATTTTCATTATGAGGTATATACTT

>60204_60204_5_NRBF2-REEP3_NRBF2_chr10_64893260_ENST00000277746_REEP3_chr10_65369947_ENST00000298249_length(amino acids)=165AA_BP=1
MGRREGPQSPRLRRAPLQSPPCSPAPLLPFLRPPLTPGSMEVMEGPLNLSQGAITERLRSFSMHDLTTIQGDEPVGQRPYQPLPEAKKKS

--------------------------------------------------------------
>60204_60204_6_NRBF2-REEP3_NRBF2_chr10_64893260_ENST00000277746_REEP3_chr10_65369947_ENST00000373758_length(transcript)=4816nt_BP=211nt
CGCGGCGCGGCGCCGGAGGAGGAAGTGGTGAGGTTGTTGCTCCTTCAGCGCCTATCGCTGGCTCTTGGGGCGCAGAGAGGGGCCGCAGTC
TCCGCGGCTGCGTCGAGCTCCCTTGCAGTCCCCTCCATGTTCCCCGGCGCCACTACTCCCCTTCCTAAGGCCGCCGCTTACCCCGGGGTC
TATGGAAGTAATGGAAGGACCCCTCAACCTGAGCCAAGGAGCAATAACTGAACGTTTAAGAAGCTTCAGTATGCATGATTTAACAACTAT
CCAAGGTGATGAGCCTGTGGGACAAAGACCATACCAACCTCTACCAGAAGCAAAAAAGAAAAGTAAACCAGCCCCCAGTGAATCAGCAGG
TTATGGAATTCCACTGAAAGACGGAGATGAGAAAACAGATGAAGAAGCAGAGGGGCCATATTCAGATAATGAGATGTTAACACACAAAGG
GCTTCGAAGATCGCAAAGCATGAAATCTGTGAAAACCACCAAAGGCCGCAAAGAGGTGCGGTACGGGTCACTAAAATACAAAGTGAAGAA
ACGACCACAAGTGTATTTTTAGTCATCTACACGTCAAATATCCCAAGACAGATTATGCTAAATACATCGACTTCATCTTCTAACATGATA
TATTCAGGATTTACACATTAAAATGATTATTTAAATTGTGGCAGTGATGGGGTTTACTTTCATGAATTTAAATTGTTTTTATTTCTGTAA
CAATTGCTTCCAAATATTGACTACTAAAGGCAGTTCTGCAAGATGTACTAAATATGTATATTAGAAATTATAGAAAATCATGTTGTCCGT
TTTCAAATTCATCAACAGCCTAGAGTGCCTGAGATATAAGATGAAACACAAATCCACAGTATACTTGAAAGGAGCCTTTTTACGGTTCAG
GATAAATCAGCCTTTGTGATGTACTGTGTTTACCTCCTTTTGTGTTGTATCTGGTAATTAAATAGGCCTCAGATTCAGCAGTGACATAAC
AAGGACATAATGTAAGATAATAAAGTAGGTTTTATATATTCTTTAAATTTTTACTTATATAATACTTTCTAGTTTTTCCACCATCAGCTG
AAAGTTTTTGAAACAAATATTTGAAAACCAGGTATCCACACATAGCACTTTTATTCCTGACTAGTTTTGCACACTTGAAAATTGTTTACT
TATTTTACAACTGTTTTACTGATGCTATCTTTATTGTTTTTGCCGTATTCTGACATGTCAAATCTATGCCTTGAATTATATCATCTCTTT
TCCTGTGGGTTTCATTTGTTAAATTCATTGGATTTTAATAATATAAAAGTATAGCTAATTGTTCAGTTTTAACTATTTTTAATTATCTTC
TTAACAAATAAGAAGTTGCTTTAAACATTAACCAATTTTCTATATTTAGCTATACAGAGTAATTGAACTTAACATGTTTTTGTCAACACC
AATTACATTTTCAGCTTTTAAAAATGGTAGCTTTTGTGAAATAGAATCAGTGACCAGTATAGCACTTAGATCCCTTCTAACTCATATAAT
TTTTCTCAGCCAATCCATTCACAAGCTTGGCATTGACATGTGCTGCTAGTTTATAAACTGGCATTGACGAAAATCATTTGAATCTCTTCT
GGCTGAGATAATTTGCCAATGCAAAATACAGTTGTCATTAATCCTGCACATTAGAAATTATTAGAAACATATTACTTTTTAACTTTAAAT
CTCAAAGAGATTTTGAGTTATTGAATTCTTAAGGCTTTCTTAGCTTGAACTGATAACTATGCATTATGAACCCTAAGTCAATATATTTTT
GGTGGTTTTAGTGATCAGTAATCAAATTTGTACTTATTATGCTTGTTCAGGTAATTTACTTGACTGTTCTATTTGTTTGTCCAAAAGATA
AAATGATGAGAGAGATTCGAGAGGTCTTTGATCTGTCTCCCTTTTAAGAAATGAAGCCAGCTGGTAATGTATATTCAGGACTTCCTCAGA
GTATTGGCCAAGAACATAATGTTTACACAGGAGTACCTTGGTATAATGCATACATTGTCTCATGATACTAGTCATAAAATATTTTATGGA
TTATTTCACATTCTTCATATATAACAAGTAAAATTAATTCAGTTTTCTTCTCCCAACGTTTAATTCTGAATAACTCTATCTACTTTACCC
TAATTTTTAGCCTCTTAATTTCTGGAAGGACTCTAATTTCTATTCCAAATTTCTATGAATTCTAATTGTAAATTATCGGAACAGAGTTTT
ATTTATATGACCTGGTACTAGACTTCTTAATATAACTGTTACACTGTCCTTGTCTTTCCTACTCAAAGACAGTATCATCTGAAGTTGCCT
AATAAGGTCATGTGAGTCAAGAACTTTATCTGTGGGAGCTGATTTGCACCATTTTACCTTTTTTTTTTTTTTTTTTTTGAGACGGAGTCT
TGCTCTGTCACCAGGCTGGAGTGCAGTGGCGCGATCTCGGCTCACTACAACCTCTGCCTCCCGGGTTCGAGCGATTCTCCTGCCTCGGCC
TCCCGAGTAACTGGGTCTACAGGCCCGTGCTACCACGCCCAGCTAATTTTTGTCTTTTTAGTAGAGACAGGGTTTAACCATGTTGCCCAG
GATGGTCTCCATCTCTTGACCTCGTGATCCGCCCGCCTCGGCCTCCCAAACTTCTGGGATTACAGGCGTGAGCCACCGCACCCAGCCACC
ATTTTATCTCTCTAAAGTCTGGTCCCAGTATTAAACCTATTCTTTAGTAAACTCATATTACTGTTCTAAATTGAAGAAATTATTTATTAC
TCTGTACTTCTAGACTCAAAATTCTTTATCAAAGATAGTCTCAAAGAGGTAGTACAAGTCCTGTTTAACTGCACTTTTTCACATTCACAG
TGCTTCCTCTGATATCTTTCCTTACATCATTATACACTGTTGATATCATTTTACTCTTCTTTCTCTTCTACATTTCTTAAATTTTGGTTC
TTTTCCTGTACATGTGTTTTAGCGGGGCCCTTTTCTTTGAACTTTGTCTAATTAGCCTGTACATTTTTGTTTCTTTTAAGGTAGAACAGA
TCTTTTTTTGTTTCTCCTTTTAAGTCTACTGGTTTTAAAAGAGGTAAATGTATCCATAGACCACAGTGCCTTGCTTTTTCCTCTGCCAGC
ACATGGAGCACGGGATTAGATGCACAAACCTATTTAGGGAACTATTTTGGTAGATGTTTGAGTTTATACAGAAATTGCAGCTGGTATTTT
ATTTTGCTGTACATTTACTCAACTTGTCCATTAGTATTTAACTATTTCCAGAGTTTGTTTAGGAGTAAGAATTGACCCATTCGTTAGTTT
ACCATATTTTTTCCTGGTATAAAAAGGAGCCAGAAATAAGCCTTATTGCTAAATAATTAATTATGTAAGCCCACCTAGGTCCTGCATAAG
ATCCCCCTCACATACTTCACAATATATATGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTATTTGGCTAAAAAATTATA
CTGCCAAAATTACTGATTATAAATACTTGACTACACTGATTGATGGGACAAAATGATTAAAGTATTTTCAGGGATCTTATTCCATATGTC
ACCACCAAAGATTTCTACAGTGTTATAAAGTATATAAATATTCCAAATTTCTGTGGTTAAATATTTTTTTCTTTTTTTTCCTTTTTTAGA
ATAACACAGTCTGTGCTTTCCAAAAATGCTTGAACTTTTATGTTGTTAAGAAATATATAATGATATCTTACATTAAGCATGAGTCTAATT
TGTATTAATTGGGATGGACTAAATTTTCATTTGATTATCAGGAAAATTAAGGAGTTATATATTTAAAAGCAATTTTCTGTGTTTTCTTCT
TTGTAAGTTGACTCATTTGTGAAGCAATTAGGCAAATTTTGAGAAGATCATTGTTATTGTGGTTTGCAGTATATATTTCTTAGTAAATAT
CACTTAAGATTAAATTTTTCAGAAAGAAAATTATAGCTTTTTTCCCAAAATATTTTTAAGATTTAATCTTTTTGTAGTATGCTACAGATT
TAATTATATTAACTCTTTTTTAAGACATTGACCATGACTTAACATTTTGCCTTCTAACACCTTTTAAATCTATGTACTTTAATAGTTAAG
AGAAAATAAGTTTGCAGATTTTTAATAATCTGTTTGTAAAAGGCTATCTCTAAGCCTAGTATGTGGGTAATTTTACAGGTGTGTTTTTTG
ATAACTTTAATATAAAATAAACTCATTTTATTTGTGGCAATTCGCGTTTCTTTTTTTATGCCAGAGTACATATGTTGGATTCCATGAATT
GGTATTACTTATTATTATGTGTTGATTAAATATATGCACACACTTAGGATTACAGATCACAGAGCAAATTATGAAAATCATAAACATTCT
GGTATGGTCATCCATAGGATTATGAAAAAGAAATACTGAATTGTTAAATTTGGATGTTAGAAAGGAAAGATAGGAAAAACAATGAGTACA
GAAATCCTCACCATCAATTTGGATGGGTTAGCTGTCTCAGGCATAAAATGTAACACAAAATTCAGATTTATGTATCCTGGAAATGTTCTG
GGGTTCCATCTGTTTTAAAGTTAGACGTCTGTCTGCCTCACATTTAAGCTTTAGAGAGAAATCCTATGTTTTAAGAAGTTTCTTTGTGTT
ACTTCATTATGACACATAATGCGTGTTAAGGTCTTTCTAGATAGCATTTTAAATGGAATTATTTTCATTTTCATTATGAGGTATATACTT

>60204_60204_6_NRBF2-REEP3_NRBF2_chr10_64893260_ENST00000277746_REEP3_chr10_65369947_ENST00000373758_length(amino acids)=165AA_BP=1
MGRREGPQSPRLRRAPLQSPPCSPAPLLPFLRPPLTPGSMEVMEGPLNLSQGAITERLRSFSMHDLTTIQGDEPVGQRPYQPLPEAKKKS

--------------------------------------------------------------

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Fusion Gene PPI Analysis for NRBF2-REEP3


check button Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in

ChiPPI page.


check button Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160)
HgeneHgene's interactorsTgeneTgene's interactors


check button - Retained PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenStill interaction with


check button - Lost PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


check button - Retained PPIs, but lost function due to frame-shift fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


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Related Drugs for NRBF2-REEP3


check button Drugs targeting genes involved in this fusion gene.
(DrugBank Version 5.1.8 2021-05-08)
PartnerGeneUniProtAccDrugBank IDDrug nameDrug activityDrug typeDrug status

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Related Diseases for NRBF2-REEP3


check button Diseases associated with fusion partners.
(DisGeNet 4.0)
PartnerGeneDisease IDDisease name# pubmedsSource