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Center for Computational Systems Medicine
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Fusion Gene Summary

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Fusion Gene ORF analysis

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Fusion Genomic Features

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Fusion Protein Features

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Fusion Gene Sequence

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Fusion Gene PPI analysis

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Related Drugs

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Related Diseases

Fusion gene:NRD1-VPS53 (FusionGDB2 ID:60237)

Fusion Gene Summary for NRD1-VPS53

check button Fusion gene summary
Fusion gene informationFusion gene name: NRD1-VPS53
Fusion gene ID: 60237
HgeneTgene
Gene symbol

NRD1

VPS53

Gene ID

4898

55275

Gene namenardilysin convertaseVPS53 subunit of GARP complex
SynonymsNRD1|hNRD1|hNRD2HCCS1|PCH2E|hVps53L|pp13624
Cytomap

1p32.3

17p13.3

Type of geneprotein-codingprotein-coding
DescriptionnardilysinNRD convertasenardilysin (N-arginine dibasic convertase)vacuolar protein sorting-associated protein 53 homologVPS53, GARP complex subunit
Modification date2020032020200313
UniProtAcc..
Ensembl transtripts involved in fusion geneENST00000352171, ENST00000354831, 
ENST00000539524, ENST00000485608, 
ENST00000544028, 		ENST00000291074, 
ENST00000401468, ENST00000446250, 
ENST00000571805, ENST00000576149, 
ENST00000574029, ENST00000437048, 
Fusion gene scores* DoF score5 X 7 X 4=14013 X 13 X 8=1352
# samples 516
** MAII scorelog2(5/140*10)=-1.48542682717024
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0		log2(16/1352*10)=-3.07895134139482
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0
Context

PubMed: NRD1 [Title/Abstract] AND VPS53 [Title/Abstract] AND fusion [Title/Abstract]

Most frequent breakpointNRD1(52258049)-VPS53(440416), # samples:2
Anticipated loss of major functional domain due to fusion event.NRD1-VPS53 seems lost the major protein functional domain in Hgene partner, which is a essential gene due to the frame-shifted ORF.
NRD1-VPS53 seems lost the major protein functional domain in Tgene partner, which is a tumor suppressor due to the frame-shifted ORF.
* DoF score (Degree of Frequency) = # partners X # break points X # cancer types
** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)

check button Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez
PartnerGeneGO IDGO termPubMed ID
HgeneNRD1

GO:0051044

positive regulation of membrane protein ectodomain proteolysis

18355445

HgeneNRD1

GO:0052548

regulation of endopeptidase activity

18355445


check buttonFusion gene breakpoints across NRD1 (5'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check buttonFusion gene breakpoints across VPS53 (3'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check button Fusion gene information from two resources (ChiTars 5.0 and ChimerDB 4.0)
* All genome coordinats were lifted-over on hg19.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
SourceDiseaseSampleHgeneHchrHbpHstrandTgeneTchrTbpTstrand
ChimerDB4LGGTCGA-E1-A7YL-01ANRD1chr1

52258049

-VPS53chr17

440416

-
ChimerDB4LGGTCGA-E1-A7YLNRD1chr1

52258048

-VPS53chr17

440416

-
ChimerDB4LGGTCGA-E1-A7YLNRD1chr1

52258049

-VPS53chr17

440416

-
ChimerDB4LGGTCGA-E1-A7YLNRD1chr1

52260144

-VPS53chr17

440416

-


Top

Fusion Gene ORF analysis for NRD1-VPS53

check button Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
ORFHenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrand
5CDS-5UTRENST00000352171ENST00000291074NRD1chr1

52258048

-VPS53chr17

440416

-
5CDS-5UTRENST00000352171ENST00000291074NRD1chr1

52258049

-VPS53chr17

440416

-
5CDS-5UTRENST00000352171ENST00000291074NRD1chr1

52260144

-VPS53chr17

440416

-
5CDS-5UTRENST00000352171ENST00000401468NRD1chr1

52258048

-VPS53chr17

440416

-
5CDS-5UTRENST00000352171ENST00000401468NRD1chr1

52258049

-VPS53chr17

440416

-
5CDS-5UTRENST00000352171ENST00000401468NRD1chr1

52260144

-VPS53chr17

440416

-
5CDS-5UTRENST00000352171ENST00000446250NRD1chr1

52258048

-VPS53chr17

440416

-
5CDS-5UTRENST00000352171ENST00000446250NRD1chr1

52258049

-VPS53chr17

440416

-
5CDS-5UTRENST00000352171ENST00000446250NRD1chr1

52260144

-VPS53chr17

440416

-
5CDS-5UTRENST00000352171ENST00000571805NRD1chr1

52258048

-VPS53chr17

440416

-
5CDS-5UTRENST00000352171ENST00000571805NRD1chr1

52258049

-VPS53chr17

440416

-
5CDS-5UTRENST00000352171ENST00000571805NRD1chr1

52260144

-VPS53chr17

440416

-
5CDS-5UTRENST00000352171ENST00000576149NRD1chr1

52258048

-VPS53chr17

440416

-
5CDS-5UTRENST00000352171ENST00000576149NRD1chr1

52258049

-VPS53chr17

440416

-
5CDS-5UTRENST00000352171ENST00000576149NRD1chr1

52260144

-VPS53chr17

440416

-
5CDS-5UTRENST00000354831ENST00000291074NRD1chr1

52258048

-VPS53chr17

440416

-
5CDS-5UTRENST00000354831ENST00000291074NRD1chr1

52258049

-VPS53chr17

440416

-
5CDS-5UTRENST00000354831ENST00000291074NRD1chr1

52260144

-VPS53chr17

440416

-
5CDS-5UTRENST00000354831ENST00000401468NRD1chr1

52258048

-VPS53chr17

440416

-
5CDS-5UTRENST00000354831ENST00000401468NRD1chr1

52258049

-VPS53chr17

440416

-
5CDS-5UTRENST00000354831ENST00000401468NRD1chr1

52260144

-VPS53chr17

440416

-
5CDS-5UTRENST00000354831ENST00000446250NRD1chr1

52258048

-VPS53chr17

440416

-
5CDS-5UTRENST00000354831ENST00000446250NRD1chr1

52258049

-VPS53chr17

440416

-
5CDS-5UTRENST00000354831ENST00000446250NRD1chr1

52260144

-VPS53chr17

440416

-
5CDS-5UTRENST00000354831ENST00000571805NRD1chr1

52258048

-VPS53chr17

440416

-
5CDS-5UTRENST00000354831ENST00000571805NRD1chr1

52258049

-VPS53chr17

440416

-
5CDS-5UTRENST00000354831ENST00000571805NRD1chr1

52260144

-VPS53chr17

440416

-
5CDS-5UTRENST00000354831ENST00000576149NRD1chr1

52258048

-VPS53chr17

440416

-
5CDS-5UTRENST00000354831ENST00000576149NRD1chr1

52258049

-VPS53chr17

440416

-
5CDS-5UTRENST00000354831ENST00000576149NRD1chr1

52260144

-VPS53chr17

440416

-
5CDS-5UTRENST00000539524ENST00000291074NRD1chr1

52258048

-VPS53chr17

440416

-
5CDS-5UTRENST00000539524ENST00000291074NRD1chr1

52258049

-VPS53chr17

440416

-
5CDS-5UTRENST00000539524ENST00000291074NRD1chr1

52260144

-VPS53chr17

440416

-
5CDS-5UTRENST00000539524ENST00000401468NRD1chr1

52258048

-VPS53chr17

440416

-
5CDS-5UTRENST00000539524ENST00000401468NRD1chr1

52258049

-VPS53chr17

440416

-
5CDS-5UTRENST00000539524ENST00000401468NRD1chr1

52260144

-VPS53chr17

440416

-
5CDS-5UTRENST00000539524ENST00000446250NRD1chr1

52258048

-VPS53chr17

440416

-
5CDS-5UTRENST00000539524ENST00000446250NRD1chr1

52258049

-VPS53chr17

440416

-
5CDS-5UTRENST00000539524ENST00000446250NRD1chr1

52260144

-VPS53chr17

440416

-
5CDS-5UTRENST00000539524ENST00000571805NRD1chr1

52258048

-VPS53chr17

440416

-
5CDS-5UTRENST00000539524ENST00000571805NRD1chr1

52258049

-VPS53chr17

440416

-
5CDS-5UTRENST00000539524ENST00000571805NRD1chr1

52260144

-VPS53chr17

440416

-
5CDS-5UTRENST00000539524ENST00000576149NRD1chr1

52258048

-VPS53chr17

440416

-
5CDS-5UTRENST00000539524ENST00000576149NRD1chr1

52258049

-VPS53chr17

440416

-
5CDS-5UTRENST00000539524ENST00000576149NRD1chr1

52260144

-VPS53chr17

440416

-
5CDS-intronENST00000352171ENST00000574029NRD1chr1

52258048

-VPS53chr17

440416

-
5CDS-intronENST00000352171ENST00000574029NRD1chr1

52258049

-VPS53chr17

440416

-
5CDS-intronENST00000352171ENST00000574029NRD1chr1

52260144

-VPS53chr17

440416

-
5CDS-intronENST00000354831ENST00000574029NRD1chr1

52258048

-VPS53chr17

440416

-
5CDS-intronENST00000354831ENST00000574029NRD1chr1

52258049

-VPS53chr17

440416

-
5CDS-intronENST00000354831ENST00000574029NRD1chr1

52260144

-VPS53chr17

440416

-
5CDS-intronENST00000539524ENST00000574029NRD1chr1

52258048

-VPS53chr17

440416

-
5CDS-intronENST00000539524ENST00000574029NRD1chr1

52258049

-VPS53chr17

440416

-
5CDS-intronENST00000539524ENST00000574029NRD1chr1

52260144

-VPS53chr17

440416

-
5UTR-3CDSENST00000485608ENST00000437048NRD1chr1

52258048

-VPS53chr17

440416

-
5UTR-3CDSENST00000485608ENST00000437048NRD1chr1

52258049

-VPS53chr17

440416

-
5UTR-3CDSENST00000485608ENST00000437048NRD1chr1

52260144

-VPS53chr17

440416

-
5UTR-5UTRENST00000485608ENST00000291074NRD1chr1

52258048

-VPS53chr17

440416

-
5UTR-5UTRENST00000485608ENST00000291074NRD1chr1

52258049

-VPS53chr17

440416

-
5UTR-5UTRENST00000485608ENST00000291074NRD1chr1

52260144

-VPS53chr17

440416

-
5UTR-5UTRENST00000485608ENST00000401468NRD1chr1

52258048

-VPS53chr17

440416

-
5UTR-5UTRENST00000485608ENST00000401468NRD1chr1

52258049

-VPS53chr17

440416

-
5UTR-5UTRENST00000485608ENST00000401468NRD1chr1

52260144

-VPS53chr17

440416

-
5UTR-5UTRENST00000485608ENST00000446250NRD1chr1

52258048

-VPS53chr17

440416

-
5UTR-5UTRENST00000485608ENST00000446250NRD1chr1

52258049

-VPS53chr17

440416

-
5UTR-5UTRENST00000485608ENST00000446250NRD1chr1

52260144

-VPS53chr17

440416

-
5UTR-5UTRENST00000485608ENST00000571805NRD1chr1

52258048

-VPS53chr17

440416

-
5UTR-5UTRENST00000485608ENST00000571805NRD1chr1

52258049

-VPS53chr17

440416

-
5UTR-5UTRENST00000485608ENST00000571805NRD1chr1

52260144

-VPS53chr17

440416

-
5UTR-5UTRENST00000485608ENST00000576149NRD1chr1

52258048

-VPS53chr17

440416

-
5UTR-5UTRENST00000485608ENST00000576149NRD1chr1

52258049

-VPS53chr17

440416

-
5UTR-5UTRENST00000485608ENST00000576149NRD1chr1

52260144

-VPS53chr17

440416

-
5UTR-intronENST00000485608ENST00000574029NRD1chr1

52258048

-VPS53chr17

440416

-
5UTR-intronENST00000485608ENST00000574029NRD1chr1

52258049

-VPS53chr17

440416

-
5UTR-intronENST00000485608ENST00000574029NRD1chr1

52260144

-VPS53chr17

440416

-
Frame-shiftENST00000539524ENST00000437048NRD1chr1

52258048

-VPS53chr17

440416

-
Frame-shiftENST00000539524ENST00000437048NRD1chr1

52258049

-VPS53chr17

440416

-
Frame-shiftENST00000539524ENST00000437048NRD1chr1

52260144

-VPS53chr17

440416

-
In-frameENST00000352171ENST00000437048NRD1chr1

52258048

-VPS53chr17

440416

-
In-frameENST00000352171ENST00000437048NRD1chr1

52258049

-VPS53chr17

440416

-
In-frameENST00000352171ENST00000437048NRD1chr1

52260144

-VPS53chr17

440416

-
In-frameENST00000354831ENST00000437048NRD1chr1

52258048

-VPS53chr17

440416

-
In-frameENST00000354831ENST00000437048NRD1chr1

52258049

-VPS53chr17

440416

-
In-frameENST00000354831ENST00000437048NRD1chr1

52260144

-VPS53chr17

440416

-
intron-3CDSENST00000544028ENST00000437048NRD1chr1

52258048

-VPS53chr17

440416

-
intron-3CDSENST00000544028ENST00000437048NRD1chr1

52258049

-VPS53chr17

440416

-
intron-3CDSENST00000544028ENST00000437048NRD1chr1

52260144

-VPS53chr17

440416

-
intron-5UTRENST00000544028ENST00000291074NRD1chr1

52258048

-VPS53chr17

440416

-
intron-5UTRENST00000544028ENST00000291074NRD1chr1

52258049

-VPS53chr17

440416

-
intron-5UTRENST00000544028ENST00000291074NRD1chr1

52260144

-VPS53chr17

440416

-
intron-5UTRENST00000544028ENST00000401468NRD1chr1

52258048

-VPS53chr17

440416

-
intron-5UTRENST00000544028ENST00000401468NRD1chr1

52258049

-VPS53chr17

440416

-
intron-5UTRENST00000544028ENST00000401468NRD1chr1

52260144

-VPS53chr17

440416

-
intron-5UTRENST00000544028ENST00000446250NRD1chr1

52258048

-VPS53chr17

440416

-
intron-5UTRENST00000544028ENST00000446250NRD1chr1

52258049

-VPS53chr17

440416

-
intron-5UTRENST00000544028ENST00000446250NRD1chr1

52260144

-VPS53chr17

440416

-
intron-5UTRENST00000544028ENST00000571805NRD1chr1

52258048

-VPS53chr17

440416

-
intron-5UTRENST00000544028ENST00000571805NRD1chr1

52258049

-VPS53chr17

440416

-
intron-5UTRENST00000544028ENST00000571805NRD1chr1

52260144

-VPS53chr17

440416

-
intron-5UTRENST00000544028ENST00000576149NRD1chr1

52258048

-VPS53chr17

440416

-
intron-5UTRENST00000544028ENST00000576149NRD1chr1

52258049

-VPS53chr17

440416

-
intron-5UTRENST00000544028ENST00000576149NRD1chr1

52260144

-VPS53chr17

440416

-
intron-intronENST00000544028ENST00000574029NRD1chr1

52258048

-VPS53chr17

440416

-
intron-intronENST00000544028ENST00000574029NRD1chr1

52258049

-VPS53chr17

440416

-
intron-intronENST00000544028ENST00000574029NRD1chr1

52260144

-VPS53chr17

440416

-

check buttonORFfinder result based on the fusion transcript sequence of in-frame fusion genes.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandSeq length
(transcript)		BP loci
(transcript)		Predicted start
(transcript)		Predicted stop
(transcript)		Seq length
(amino acids)
ENST00000354831NRD1chr152258048-ENST00000437048VPS53chr17440416-14310321719038491219
ENST00000352171NRD1chr152258048-ENST00000437048VPS53chr17440416-14106301319036451151
ENST00000354831NRD1chr152258049-ENST00000437048VPS53chr17440416-14310321719038491219
ENST00000352171NRD1chr152258049-ENST00000437048VPS53chr17440416-14106301319036451151
ENST00000354831NRD1chr152260144-ENST00000437048VPS53chr17440416-14262316919038011203
ENST00000352171NRD1chr152260144-ENST00000437048VPS53chr17440416-14058296519035971135

check buttonDeepORF prediction of the coding potential based on the fusion transcript sequence of in-frame fusion genes. DeepORF is a coding potential classifier based on convolutional neural network by comparing the real Ribo-seq data. If the no-coding score < 0.5 and coding score > 0.5, then the in-frame fusion transcript is predicted as being likely translated.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandNo-coding scoreCoding score
ENST00000354831ENST00000437048NRD1chr152258048-VPS53chr17440416-0.0003961730.9996038
ENST00000352171ENST00000437048NRD1chr152258048-VPS53chr17440416-0.0003789940.99962103
ENST00000354831ENST00000437048NRD1chr152258049-VPS53chr17440416-0.0003961730.9996038
ENST00000352171ENST00000437048NRD1chr152258049-VPS53chr17440416-0.0003789940.99962103
ENST00000354831ENST00000437048NRD1chr152260144-VPS53chr17440416-0.0004586110.9995414
ENST00000352171ENST00000437048NRD1chr152260144-VPS53chr17440416-0.0007147610.9992853

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Fusion Genomic Features for NRD1-VPS53


check buttonFusionAI prediction of the potential fusion gene breakpoint based on the pre-mature RNA sequence context (+/- 5kb of individual partner genes, total 20kb length sequence). FusionAI is a fusion gene breakpoint classifier based on convolutional neural network by comparing the fusion positive and negative sequence context of ~ 20K fusion gene data. From here, we can have the relative potentency of the 20K genomic sequence how individual sequnce will be likely used as the gene fusion breakpoints.
HgeneHchrHbpHstrandTgeneTchrTbpTstrand1-pp (fusion gene breakpoint)

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions. We integrated a total of 44 different types of human genomic feature loci information across five big categories including virus integration sites, repeats, structural variants, chromatin states, and gene expression regulation. More details are in help page.
genomic feature

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions that are ovelapped with the top 1% feature importance score regions. More details are in help page.

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Fusion Protein Features for NRD1-VPS53


check button Four levels of functional features of fusion genes
Go to FGviewer search page for the most frequent breakpoint (https://ccsmweb.uth.edu/FGviewer/chr1:52258049/chr17:440416)
- FGviewer provides the online visualization of the retention search of the protein functional features across DNA, RNA, protein, and pathological levels.
- How to search
1. Put your fusion gene symbol.
2. Press the tab key until there will be shown the breakpoint information filled.
4. Go down and press 'Search' tab twice.
4. Go down to have the hyperlink of the search result.
5. Click the hyperlink.
6. See the FGviewer result for your fusion gene.
FGviewer

check buttonMain function of each fusion partner protein. (from UniProt)
HgeneTgene
..
FUNCTION: Transcriptional activator which is required for calcium-dependent dendritic growth and branching in cortical neurons. Recruits CREB-binding protein (CREBBP) to nuclear bodies. Component of the CREST-BRG1 complex, a multiprotein complex that regulates promoter activation by orchestrating a calcium-dependent release of a repressor complex and a recruitment of an activator complex. In resting neurons, transcription of the c-FOS promoter is inhibited by BRG1-dependent recruitment of a phospho-RB1-HDAC1 repressor complex. Upon calcium influx, RB1 is dephosphorylated by calcineurin, which leads to release of the repressor complex. At the same time, there is increased recruitment of CREBBP to the promoter by a CREST-dependent mechanism, which leads to transcriptional activation. The CREST-BRG1 complex also binds to the NR2B promoter, and activity-dependent induction of NR2B expression involves a release of HDAC1 and recruitment of CREBBP (By similarity). {ECO:0000250}.FUNCTION: Transcriptional activator which is required for calcium-dependent dendritic growth and branching in cortical neurons. Recruits CREB-binding protein (CREBBP) to nuclear bodies. Component of the CREST-BRG1 complex, a multiprotein complex that regulates promoter activation by orchestrating a calcium-dependent release of a repressor complex and a recruitment of an activator complex. In resting neurons, transcription of the c-FOS promoter is inhibited by BRG1-dependent recruitment of a phospho-RB1-HDAC1 repressor complex. Upon calcium influx, RB1 is dephosphorylated by calcineurin, which leads to release of the repressor complex. At the same time, there is increased recruitment of CREBBP to the promoter by a CREST-dependent mechanism, which leads to transcriptional activation. The CREST-BRG1 complex also binds to the NR2B promoter, and activity-dependent induction of NR2B expression involves a release of HDAC1 and recruitment of CREBBP (By similarity). {ECO:0000250}.

check buttonRetention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at

download page


* Minus value of BPloci means that the break pointn is located before the CDS.
- In-frame and retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneNRD1chr1:52258048chr17:440416ENST00000352171-2531142_2019411152.0Compositional biasNote=Asp/Glu-rich (highly acidic)
HgeneNRD1chr1:52258048chr17:440416ENST00000352171-2531144_1539411152.0Compositional biasNote=Poly-Glu
HgeneNRD1chr1:52258049chr17:440416ENST00000352171-2531142_2019411152.0Compositional biasNote=Asp/Glu-rich (highly acidic)
HgeneNRD1chr1:52258049chr17:440416ENST00000352171-2531144_1539411152.0Compositional biasNote=Poly-Glu
HgeneNRD1chr1:52260144chr17:440416ENST00000352171-2431142_2019251152.0Compositional biasNote=Asp/Glu-rich (highly acidic)
HgeneNRD1chr1:52260144chr17:440416ENST00000352171-2431144_1539251152.0Compositional biasNote=Poly-Glu

- In-frame and not-retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
TgeneVPS53chr1:52258048chr17:440416ENST00000291074151897_138593671.0Coiled coilOntology_term=ECO:0000255
TgeneVPS53chr1:52258048chr17:440416ENST00000437048162297_138622833.0Coiled coilOntology_term=ECO:0000255
TgeneVPS53chr1:52258048chr17:440416ENST00000571805161997_138622700.0Coiled coilOntology_term=ECO:0000255
TgeneVPS53chr1:52258049chr17:440416ENST00000291074151897_138593671.0Coiled coilOntology_term=ECO:0000255
TgeneVPS53chr1:52258049chr17:440416ENST00000437048162297_138622833.0Coiled coilOntology_term=ECO:0000255
TgeneVPS53chr1:52258049chr17:440416ENST00000571805161997_138622700.0Coiled coilOntology_term=ECO:0000255
TgeneVPS53chr1:52260144chr17:440416ENST00000291074151897_138593671.0Coiled coilOntology_term=ECO:0000255
TgeneVPS53chr1:52260144chr17:440416ENST00000437048162297_138622833.0Coiled coilOntology_term=ECO:0000255
TgeneVPS53chr1:52260144chr17:440416ENST00000571805161997_138622700.0Coiled coilOntology_term=ECO:0000255


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Fusion Gene Sequence for NRD1-VPS53


check button For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. To have fusion amino acid sequence, we ran ORFfinder and chose the longest ORF among the all predicted ones.
>60237_60237_1_NRD1-VPS53_NRD1_chr1_52258048_ENST00000352171_VPS53_chr17_440416_ENST00000437048_length(transcript)=14106nt_BP=3013nt
AGTAGCGTCATCGGCGGCCGGGAGGGCGGAGGGACGAGGGAAGTCGGCGAGAGGGAGACTGGGTTGGGGGAGGGGTTCAGGCCTGTTCCC
CGCGGCTGCGGCAGCACCAGGGCCGGCCGCCACCGCCTCTAGAACGCGGAGGAGGTGGGTCCTGGGAAGCGGGATGTCCATCGCTCCAGC
TTGGTGGTGAATGCTGAGGAGAGTCACTGTTGCTGCAGTCTGTGCCACCCGGAGGAAGTTGTGTGAGGCCGGGCGGGAGCTCGCGGCGCT
CTGGGGAATCGAAACGCGGGGTCGGTGCGAAGACTCTGCTGCTGCCAGACCCTTTCCTATTCTGGCCATGCCTGGAAGGAACAAGGCGAA
GTCTACCTGCAGCTGCCCTGACCTGCAGCCCAATGGACAGGATCTGGGCGAGAACAGCCGGGTTGCCCGTCTAGGAGCGGATGAATCTGA
GGAAGAGGGACGGAGGGGGTCTCTCAGTAATGCTGGGGACCCTGAGATCGTCAAGTCTCCCAGCGACCCCAAGCAATACCGATACATCAA
ATTACAGAATGGCTTGCAGGCACTTCTGATTTCAGACCTAAGTAATATGGAAGGTAAAACAGGAAATACAACAGATGATGAAGAAGAAGA
GGAGGTGGAGGAAGAAGAAGAAGATGATGATGAAGATTCTGGAGCTGAAATAGAAGATGACGATGAAGAGGGTTTTGATGATGAAGATGA
GTTTGATGATGAACATGATGATGATCTTGATACTGAGGATAATGAATTGGAAGAATTAGAAGAGAGAGCAGAAGCTAGAAAAAAAACTAC
TGAAAAACAGTCTGCAGCGGCTCTTTGTGTTGGAGTTGGGAGTTTCGCTGATCCAGATGACCTGCCGGGGCTGGCACACTTTTTGGAGCA
CATGGTATTCATGGGTAGTTTGAAATATCCAGATGAGAATGGATTTGATGCCTTCCTGAAGAAGCATGGGGGTAGTGATAATGCCTCAAC
TGATTGTGAACGCACTGTCTTTCAGTTTGATGTCCAGAGGAAGTACTTCAAGGAAGCTCTTGATAGATGGGCGCAGTTCTTCATCCACCC
ACTAATGATCAGAGATGCAATTGACCGTGAAGTTGAAGCTGTTGATAGTGAATATCAACTTGCAAGGCCTTCTGATGCAAACAGAAAGGA
AATGTTGTTTGGAAGCCTTGCTAGACCTGGACATCCTATGGGAAAATTTTTTTGGGGAAATGCTGAGACGCTCAAGCATGAGCCAAGAAA
GAATAATATTGATACACATGCTAGATTGAGAGAATTCTGGATGCGTTACTACTCTTCTCATTACATGACTTTAGTGGTTCAATCCAAAGA
AACACTGGATACTTTGGAAAAGTGGGTGACTGAAATCTTCTCTCAGATACCAAACAATGGGTTACCCAGACCAAACTTTGGCCATTTAAC
GGATCCATTTGACACACCAGCATTTAACAAACTTTATAGAGTTGTTCCAATCAGAAAAATTCATGCTCTGACCATCACATGGGCACTTCC
TCCTCAACAGCAACATTACAGGGTGAAGCCACTTCATTATATATCCTGGCTGGTTGGACATGAAGGCAAAGGCAGCATTCTTTCTTTCCT
TAGGAAAAAATGCTGGGCTCTTGCACTGTTTGGTGGAAATGGTGAGACAGGATTTGAGCAAAATTCTACTTATTCAGTGTTCAGCATTTC
TATTACATTGACTGATGAGGGTTATGAACATTTTTATGAGGTTGCTTACACTGTCTTTCAGTATTTAAAAATGCTGCAGAAGCTAGGCCC
AGAAAAAAGAATTTTTGAAGAGATTCGGAAAATTGAGGATAATGAATTTCATTACCAAGAACAGACAGATCCAGTTGAGTATGTGGAAAA
CATGTGTGAGAACATGCAGCTGTACCCATTGCAGGACATTCTCACTGGAGATCAGCTTCTTTTTGAATACAAGCCAGAAGTCATTGGTGA
AGCCTTGAATCAGCTAGTTCCTCAAAAAGCAAATCTTGTTTTACTGTCTGGTGCTAATGAGGGAAAATGTGACCTCAAGGAGAAATGGTT
TGGAACTCAATATAGTATAGAAGATATTGAAAACTCTTGGGCTGAACTGTGGAATAGTAATTTCGAATTAAATCCAGATCTTCATCTTCC
AGCTGAAAACAAGTACATAGCCACGGACTTTACGTTGAAGGCTTTCGATTGCCCGGAAACAGAATACCCAGTTAAAATTGTGAATACTCC
ACAAGGTTGCCTGTGGTATAAGAAAGACAACAAATTCAAAATCCCCAAAGCATATATACGTTTCCATCTAATTTCACCGTTGATACAGAA
ATCTGCAGCAAATGTGGTCCTCTTTGATATCTTTGTCAATATCCTTACGCATAACCTTGCGGAACCAGCTTATGAAGCAGATGTGGCACA
GCTGGAGTATAAACTGGTAGCTGGAGAACATGGTTTAATTATTCGAGTGAAAGGATTTAACCACAAACTACCTCTACTGTTTCAGCTCAT
TATTGACTACTTAGCTGAGTTCAATTCCACACCAGCTGTCTTTACAATGATAACTGAGCAGTTGAAGAAGACCTACTTTAACATCCTCAT
CAAGCCCGAGACTTTGGCCAAAGATGTACGGCTTTTAATCTTGGAATATGCCCGTTGGTCTATGATTGACAAGTACCAGGCTTTGATGGA
CGGCCTTTCCCTTGAGTCTCTGCTGAGCTTCGTCAAAGAATTCAAATCCCAGCTCTTTGTGGAGGGCCTGGTACAAGGGAATGTCACAAG
CACAGAATCTATGGATTTCCTGAAATATGTTGTTGACAAACTAAACTTCAAGCCTCTGGAGCAGGAGATGCCTGTGCAGTTCCAGGTGGT
AGAGCTGCCCAGTGGCCACCATCTATGCAAAGTGAAAGCTCTGAACAAGGGTGATGCCAACTCTGAAGTCACTGTGTACTACCAGTCAGG
TACCAGGAGTCTAAGAGAATATACGCTTATGGAGCTGCTTGTGATGCAGTGGCAGAACGTGGAGCACGTTGGTGACCAGAGCCCCTACGT
CACCTCTGTCATTCTGCACATCAAGCAGAACGTCCCCATCATCCGTGACAACCTGGCTTCCACACGCAAGTACTTCACTCAGTTCTGCGT
TAAATTTGCAAACTCCTTCATTCCCAAATTCATCACCCACCTCTTCAAGTGCAAGCCAATTAGCATGGTGGGAGCAGAACAGCTGCTGCT
GGACACCCACTCGCTGAAGATGGTCCTGCTCGATCTCCCCTCCATCAGCTCGCAGGTGGTGAGGAAGGCACCCGCCAGCTACACCAAGAT
CGTTGTCAAAGGCATGACCCGGGCTGAGATGATCCTCAAGGTAGTGATGGCCCCTCATGAACCGTTGGTGGTGTTTGTTGACAACTACAT
CAAACTTCTCACAGACTGCAACACAGAAACCTTTCAGAAGATACTGGACATGAAGGGGCTGAAGAGGAGTGAGCAGAGCAGCATGCTGGA
ACTCCTGCGCCAGCGGCTCCCCGCACCGCCCTCGGGGGCAGAAAGCTCCGGCTCACTGTCCCTGACGGCGCCAACACCAGAGCAAGAGTC
GTCACGCATCCGCAAGCTCGAGAAACTCATTAAAAAGAGACTGTAGCAGCAGCAAGGGGCCCTTTGCTCCTGGCTGGAGACCCTCAGCGC
CCGTTCCCCAGAAGCCCCCAACCTCTCCTGTGCTCCCCGGCACTCTCACATCGTCGGTCTTCAAACTTCCTGGGACATGTGGGTTGTTAC
TGAGTCTCTCCCATGCCCTGTCTTACTTCCTGCCCTAATCGGAGACGCTGAGTAAGGGCTGGGCTCTAAGAGGGCGATTTAGGTGATCTC
TGGTTCGTGAAGCAGAGGCAGCAGTGGAGGATAGGTCCCTGAGCTGCCCTTGACTCATGTAGCCTCCCCATGGCAGTCACACCCTCTTGA
CACGTGGGCCCCACCCGTCCTTTTTTTTTTTTTTTTTTTTTTTTTTTGAGACAGAGTCTCGCTCTGTCACCCAGGCTGGAGTGCAGTGGC
GTGATCTCGGCTCACTGCAACCTCCGCCTCCCAGGTTCAAGCAATTCTCCTGCCTCAGCCTCCTGAGTATCGGATTACAGGCGTGAGCCA
CCGAGCCCAGCCCCTTCCTCCATTTCTTTACTCCCACCCTGCTCCTGGTTTCTAGGGAAGGGAAACCAGGAAGTTCACTTGGAAGACGTT
TCCTAGGTTTTCTCATCAGATGAAGCCATGGGAACGCCCAGGAAGTCCATACTCTCAAACCCCTTTCTGCCCACTCACCTTCAGGTCCAC
AGCACTTTCCAGCGTCATCTGAAATAGCAAAGGTGATGTGCAGCATCCCAGTGATGTGTTCCTGTGTTATGAGAAGGAGTCTGGGGTTCT
GGATGCCTCAGGAACAGAATATGGACCTTAAAGACCAGGCTGAGAGCCTGGCCTGGCACGCAGCCTGCCCGCCCCCCCCGCCCTTCCTGT
CCACCGCGGGCTCTCTGCAGCAGGGCTTGCCGAAGAGACTGCTCCCGACCTCTCATGTCATCCTGCATCCAGAGAATGGCAGCATATCAA
GCCGTTAACCCTGATTCACTCGGTTCCCTTGAAACCAGGCCTCAGTTAACCATGACCACAGCTACAGGCAAACCGCTGCTGTTGCTGCCT
GCTTTTGCTGAAGAATGATATCTTGCCAGGCACGGCGGCTCATGCCTGTAGTCGCAACACTTTGGGAGACCAAGGCAGGAGGATCACTTG
AGTCCAGGAGTTTGAGACCAGCCTGGGCAACATACAGATGTCTACAAAAATAAAAATTTGCAAGGTGTGGTGGCATGCACCTGTAGTCCC
AACTGCTAGGGAGGCTGAGGTGGGCAGATTGCTTGAGCTCAGGAGTTTGAGACCAGTCTGGGCAACCTGGCAAAACCAAAAATACAAAAA
ATTGGCTGGGTGTGGTGGCTCATGCCTGTAATCACAGCACTTTGGGAGGCTGAGGCAGGTGGATCACCTGAGGTCAGGAATTCGAGACCA
GCCTGCCCAACATGGCGAAACCCTGTCTCAACTAAAAATAAAAAAAATTAGCCGGGTGTCATGGCGAGTGCCTGTAATCCCAGCTACTGG
GGAGGCTGAGGCAGGAGAATCACTTAAACCCGGGAGGTGGAGGCTGCAGTGAGCCAAGATTTCACCACTGCACTCCAGCCTGGGTGACAG
AGCAAGACCCCTTCTCAAAAAGTTTTCAGGATAGAGGAAATTTCCTTAAAATCCATAAAACTTGTAACAGCCGTACAGTAGGAATAAGGT
TTGGAAATCTGCCTGGAAACCTGATTTCCTCATCCCCACCTTGTTTCCCAACATAACCACTGCTCTGTGCCCCTGCCCTCTCTGCCAGGC
TTTCTCCCCGATGCCGTCCAGCTCTGATCCTGAGTGTCATTTCTTCATCGGCTTCCAGGCTGTCCTTGCTAGCTGGTTTGACTCTCACGC
ATCAAGCGTCTCAAATTTGAGAATGCGGAGGAGAAAAGAAGTGTTGCGAGAAGGAGATGCGGCCTTCAGTTGAGGTCTATTAGGAAAAGA
TTCCAAATAAGACAAGGGCGGGGGGCGGCAGTCGGGAGAGCCCCCAGGAAGCCCTGTAGATGCCCCCACCCCAGCCCATGGAGTTGCTAT
GGTTAAGCAGCCTGAGCCGTACAGTTGAAAAGGGGCGGTGGGGCCCATCTCCAAATAGCACAGCCAGTTCAGCCGTCTGTCCTCAACCCA
GGAGAGCTGGGAAAGCCAGTGGACTCCTGCACCTGGTTCTTGTCACTCCTGGCGTTTGTGTACAGATCACCACTTCTCTTTTTGGTTCAT
TGTTGAGGAGTCGTTTTCCGGACGGCTCCATCACAGCATTGAGCTATCAAGCTGCTGTTTTCCACAGTTGGTGGTCACAGCCAGGGAAGT
TGCTGTCTTGATTTGTTACATTGTCAGTAATCCCCAAGGAACCAATGGATGTCAGTAGGAGTTTCTGTTAAATGTCTCCTTGATGGGGAC
TCAGTACTGTGTAGAGACGCTGTGTTTCTCTTCTGGGGGTGTGCATCAGAACCACTGGGGCCTTTTAAAATCTACAGATGCCGGCCGGGC
GCCGTGGCTCACGCCTGGAATCCCAGCACTTGGGGAGGCTGAGGCGGGCGGATCACAAGCGCAGGAAATTGAGACCATCCTTGCCAATAT
GGTGAAACCCCATCTCTACAAAAAATACAAAAATTACCGGGGTGTGGTGGCGTGCACACCTCCCAGCTACTTGGGAGGCTGAGGCAGGAG
AATCGCTTGAACCCGGGAGGCAAAGATTGCAGTGAGCCGAGATCACGCCACTGCACTCCAGCCTGGCGACAGAGTGAGACTCTATCTCAA
AACAAACAAAAAAACAGATGCCCGGAGATTTTGAGTCAGTAAGTTTGGATGGGGCCTGGCATACAGGTTTAAAAGTTCCATAGGTAGTTA
TAACGTTTACACCTTGTTAAGAACCACTGCAACAGAGAGATTTGCTTTATGGAAGGGCTCCTGCCACGCATTTTCATACATGTCTATTTT
TCTGACTCTAAGCTAAAAGTGCGCCGACACTACACTTGAGCTGGTGCCAACGTGGTGAAGATTCTCTACTGATAACAGCTTTCATTTTAA
ACTTGTGTTGGGTCAGGCGCGGTGGCTCACGCCTGTAATCCCAGCACTTTGGGAGGCCGAGGTGGGCGGATCACATGAGGTCACGAGTTT
GAGACCAGCCTGGCCAACATGGCAAAATCCCATCTCTACTAAAAATACAAAAAAAAAAAAAAAAAAAGCAGGCAGGTGGCGGGTGCCTGT
AATCCCAGCTACTTGGGAGGCTGAGGCAGGGGAATCAGTTGAATCCGGGAGGCGGAGGTTGCAGTGAGCCGAGGTCCCGCCACTGCACTC
CAGCCTGGGAGACAGAGTGAGACTCAGTTAAAAAAAAAAGACTTTTGGTGGTGGTGGGGACCATGCCCAGGATTGGGCTCTCTCCATACT
GATGAGGATTCTTCTTGTTTTGATGACCAACCCCCAAGCAGAAGCTTTATTTATTAACATCACTTCAAAAATAACGTATCAAAGGGGCAC
CCTAGGCCGGGTACTGTGGCATCACACCTGTAATGCCAGTGCTTTGAGAGGCTGAGGTGGGAAGATTGCTTGAGCCCAGGACTTCAAGAC
AAGCCTGGGCAACAGAGTGAGACCCCATCTCTATTAAAAAATAGGCCGGGCATGGTGGCTCACACTGGTAATCCCAGCACTTTGGGAGGC
CGAGGCAGGTGGATCATGTGAGGTCAGGAGTTCGAGACCAGCCTGGCCGACATGGTGAAACCCTGTCTTTACTAAAAATACAAAATTAGC
CAGGCGTGGTGGTGGGCGCCTGTAATCCCAGCTACTCAGGAGGCTGAAGCAGGAGGATCGCTTGAACCCAGGAGGCAGAGGCTGCAGTGA
GCCGAGATCATGCCATTGCACTCCTGCCTGGGTGACGGAGCAAGACTCTCTAAAAAATAATAAGGTAAAAGGAGTACCTGTGGATGAAAG
CAGCAGCTAACAGCTCTGTGATTCAGCTAGACCTAGATATTGTGCCCATTCCTTCCCCTCAGTCCATTTTCTGTAGCCCCTTTAAAAACC
AAAAAACAACTTTGAAGTCACTTTGGGTTTAAAATAAATAGTGGTAATTTGTATAATCAATAAAGAGTTCACTCTGCTCTTACTGAGGGG
ACTTGTCTGAAAGCTGGCTTAGCGGTGTCCAGGCCAGAGAACATCCTGTGTGGACTCTTAACAATGAAACAGGAGCCGCAATGGACAAGG
TGTTCTGATCTCCAAACCCAGCTCAGGGATTGAAGCTAACTACCGCCACTCCTTCCTCTCTCGAAGAACAAAGAGCCAGTACCCAGGGCT
CTGCCCACCCCCGAGAAGGGGTGCCTGATTTCTTATGTCTAGGGTGGCTCCTCTGTGCAGATCAGACAGGACTGAGAGCAGACAAGCTGA
GACCAGCATGACCAGTACAGGGCACGCAGAGCGTGGGGGCAGGTCCGAGGCTGCTGCTCGATGCAGGGTATGACACCAACCCTTCCTGAA
TTGCCATCGGATGAGGAGACCTGGTTCCCTGTTGAAAGAATGCCAGGGGAAATGCTGCATGTGCACAGCTGGAAATGGGGTTCCTTCTCT
AGGAAGAGCACTCGGAATAACCTGCTGGAAATGGGGTTCCTTCCCTAGGAAGAGCACTCAGAATAACCTGCTGGAAATGGGATTCCTTGG
CTAGGAAGAGCACTCAGAATAACCTGCTGGAAATGGGATTCCTTGGCTAGGAAGAGCACTCAGAATAACCTGCTGGAAATGGGATTCCTT
ACCTAGGAAGAGCACTCGGAATAACCTGCTGGAAATGGGATTCCTTACCTAGGAAGAGCACTCGGAATAACCTGCTGGAAATGGGGTTCC
TTCCCTAGGAAGAGCACTCGGAATAACCTGCTGGAAATGGGGTTCCTTCCCTAGGAAGAGCACTCGGAATAACCTGCTGGAAATGGGGTT
CCTTCGCTAGGAAGAGCACTCGGAATAACCTGCTGGAAATGGGATTCCTTCGCTAGGAAGAGCACTCGGAATAACCTGCTGGAAATGGGA
TTCCTTCGCTAGGAAGAGCACTCGGAATAACCTGCTGGAAATGAGATTCCTTCCCTAGGAAGAGCACTCGGAATAACCTGCTGGAAATGG
GATTCCTTCGCTAGGAAGAGCACTCGGAATAACCTGCTGGAAATGAGATTCCTTCGCTAGGAAGAGCACTCGGAATAACCTGCTGGAAAT
GGGATTCCTTCGCTAGGAAGAGCACTCGGAATAACCTGCTGGAAATGAGATTCCTTCGCTAGGAAGAGCACTCGGAATAACCTGCTGGAA
ATGGGATTCCTTCGCTAGGAAGAGCACTCGGAATAACCTGCTGGAAATGGGATTCCTTCGCTAGGAAGAGCACTCGGAATAACCTGCTGG
AAATGGGATTCCTTCCCTAGGAAGAGCACTCGGAATAACCTGCTGGAAATGAGATTCCTTCCCTAGGAAGAGCACTCGGAATAACCTGCT
GGAAATGGGATTCCTTCGCTAGGAAGAGCACTCGGAATAACCTGCTGGAAATGGGATTCCTTCGCTAGGAAGAGCACTCAGAACAACCTG
CCTGCTTGAGGGTGACAGCAAGTGTCTCACACTTCTCGTCTACTCCAAGTCAGATTCCTAAAAATAAAATAGAGCTCCAATGGGCAATTT
AAGCAAAAGCCTTAGAAACATGGACACCTGAAATGCTGGCCTACATGAAGGGTACGATGACATTTTATATATTAAATAAAAATTCCCAGT
CCTGTTTTAGTATTCATCAGAATAGCCTCTTGGACCCTCGAAGTTCTACACCTTTGGGAGATATAAATTTCCTTAAAATAAAGGGATTGC
TTCTTTGTGTAAATAGCTTTCATTTTCTCCATCTGGAAGTGATTTCTGCCTGCATGTTGGAGCACAAAATACTGCAGTTAATTAAAGCAT
TACTGGATGTCATTTGCTAGAATGTATTTCCTTACTGCTGACAGAAAACAGAACAGACTCTAGGAAAGAAGTAGCAAGTCCGTGACCCTG
GCCGCTCCTGGTGGCTGCCCTTCTCCCTTCCCTGACAGTCTAAGGAAGCAACGCGTGGGAGCAGAATGTGGCCGACTGAGCCCAGTCCTG
ACCTGCCCAGTTGCAGTGGAGCCTGTCTGTAATGTTGTGTAAAGTGTTTTGCTTCTGACTTGGAACCCTACTTGCCCTGTGAATTTCTAT
CCTGTGAACCTTCCCTTCTCTGTCCTTACCGTTCCCATCACAGCCTGCTCTTCCAGTGACGGCCAAGTGATTTCTCTCCTGCACGCATGA
GTCCATCCTGTTTCCTTAGTAGCTGGATGGACGTTTTGCCATGAAAACTCTTTGGGAAGTCTTGTGTCCTTTAGTGATTTCTCTCCTGCA
CGCATGAGTCCATCCTGTTTCCTTAGTAGCTGGTTGGACGTTTTTGCCATGAAAACTCTTCGGGAAGTCCTGTGTCCTTTCAACAGGGGA
AAACTGGCTGCGGCCCTTCCATTAGGCTCCAGGATCATTACCTCGTTTCCATTCTTTCTTTTCAACAGCTCCCCACTTTACTAGGGAAGC
CAAGGGATCAACCTAATGAGAAAAGAACCTTCCCTGTAGCCCACCTGGAAGGGCATTGCCTGCCAGCTCCTTCCTTCTCACCTATGTGAA
CAGGAGGGAAGATGCCGGCGATCCATGGATCTGTGGGACATGAAGGACGTGTCCATCAGAAATGAAAGCAGCCTGGGATTGGAAGCATCC
ACAGAAGACTTGATCTGCAGGTCTTGATTTGGACCTGGCACTTTGACACCAGGCGAGTCACTGATCCCCTGAGCATCCATTTTCAATATT
GGTGAGAGGGGATTATAATGAATATTGGCTGTGAAGGTCACACAAGACCGGGCTATATGCACTTGCTCTGCCATAAGGCAGTGTGAAGTG
TGTTCGTGATCACTTGTGGGCGGGAGCCTGTGGCTGTCTTGCCTGGACTGGCTTTTTTAAACATGGATGAGTGGTGACAAATCCTGCGGC
CGTGTGCAGGCTACATCCGCAGCGAGCTCCGCATATCTGGTCTTTGCCTTTTTAGGTCATGACTGTAATATCAAGCTTACACGAGAGTTT
TAAAAGACTGAGCAGTATCCCCTTCCCCTGGCAGCTGCTGCTTCCGTAGCATTTAGGGATAAACCTGCAGACACTGAGAAGAGAGCTTCC
TCCCTCCTGGGGCTGGTGGCGAGGCTGCCTGTTGTGGAAAATAGGGCATGTCTCCTGTGAATGCGAATTGCGAGGGTTGCCAAAGCCTCC
CTTCCAAGAAACTTGCTTAGGTGTCTGGTGTCCACAGACCAGACTCTTCTCCCGACAGGGACAAAAATTCTTGCCTGCCTTTCTTTTTCT
TTTTTTTCCTTTTACTTATTCTTGCCTTTTTTCTTCTTCTTCTTCTTTAGGTATGATGCCCCCCAAAAAACTAAGCAAGATTAACTTGGG
ACAGGCAGTTCTAACTGGGAAGCCTGAGCTCACAGGCTGTTTGGATTACTTTCCAATTGTGTTTCAAAGATGTTTAGACTTTTCCCAAGG
CCAGCTGAATCCTTATAATCAGCCCAAAAGTTCCTTTCTGTTTCTGTCTGTCCCCTTTGAGGGTGTTGACTCAGAGAACCTGGGGCAATA
TGAGATGTTAAAATAAAAATAGCGTCCAACGTCCCGCCTCCTGGGAATGCTGCTCACTTCATCCGAGGGTTCTGGGAGCTTCTGCTCAGT
CATCAAATGGAATTTGCACAATTGTCTTGCCTCCTGTTTTGGGTAATTTTTCAACAAGTGAGAAATTAAGAACAGCTTCTCAACAAACTT
CCCTCTACTTCCAGGGCCAAGAAAAGTATTTGCAGTGTGGGCTGCAGCTTTCAGGGGTCTCAGGTGAAATGGTGGCAAGAAACCCCAGCT
CCCTTCATGTGTTTGCCTTGCGCTGATGGAAAAGGAAGGCACTTCTCAGCTGCCAGAGACCACATTCCACAGGGTTCTTCACAAAATCAA
GCACTGCAGTGGACCAACTGGAGCAGCCACTGGAGGGCTTTAGAAGGCAAATGGAATACATATCAAATGCTATATAAAGAAAACATCTGT
TTACACAGAGTCCCCCACAGCCTCATACCTACACCCAATATCAAATGCTGTATAAAGAAACATCAGTTTACACACAGAGCCCCCCACAAC
CTCATACCCACACCGAATATCAAATGCTATACAAAGAAACATCAGTTTACACACAGAGTCCCCCACAGCCTCATACCCATGCCTGTCACA
TCTTTGCACAGCCCTAAAGGATCCAGAGCTTTGGATCAGCAGCTGGCTAGCTCGGAGGCCAGAGGAGGGTGCTGAGGGGAGTGGAGGTCA
GTTGGGGTAGCCCTGGGCCCTGGCTGCACAGTCCAGCTGCTGTGTGGCCTGCATGTGGTATCTTAGGTCATGAGAGGGCCTGGGCAATTC
AGTGCTATCTGTACATGTTGGTGGGGTGGGAAGGAAAAGGTAACTGTGTATTTACTGTGTCCTGGATACATTATCTCATCGGATGAAATT
CCTGCTAAGTTAAGCTCCGTTTAGTGGACGGGACTTGGAGGCTCAAAGAGGGTAAGTGACAGGCCCAAGGATATGTGCCTAGTGAGGGGT
GAGCCAGGATTCGATGTGTGACTAGTAAGGGGTCAGCCAGGATTCAATATGTGACTAGTAAGGGGTCAGCCAGGATTTCATATGGGACTA
GTAAGGGGTCGGCCAGGATTTGATACGTGACTAGCAAGGGGACAAGCCAGGATTTGATATGTGACTAGTGAGGGGCGAGCCAGGATTCGA
TATGTGACTAGTAAGGGGTCAGCCAAGATTTGATATGTGACTAGTGAGGGGCGAGACAGGATTTGATATGTGACTAGTGAGGGGCGAGCC
AGGATTTGATATGTGACTGGTGAGGGGCGAGCCAGGATTTGATATGTGACTGGTGAGGGGCGAGCCAGGATTTGATATGTGACTGGTGAG
GGGCGAGCCAGGATTTGATATGTGACTGGTGAGGGGCGAGCCAGGATTTGATATGTGACTGGTGAGGGGCGAGCCAGGATTTGATATGTG
ACTGGTGAGGGGCGAGCCAGGATTTGATATGTGACTGGTGAGGGGCGAGCCAGGATTTGATATGTGACTGGTGAGGGGCGAGCCAGGATT
TGATATGTGACTGGTGAGGGGCGAGCCAGGATTTGATATGTGACTGGTGAGGGGCGAGCCAGGATTTGATATGTGACTGGTGAGGGGCGA
GCCAGGATTTGATATGTGACTGGTGAGGGGTGGAGCCAGTCAGGATTTGATATGTGGTTAGTGAGGGGTTAGCCAGTCAGGATTTGATAT
GTGGCTAGTGAGGGGCGAGCCAGGATTTGATATGTGACTAGTAAGGGGGTGAGCCAGGATTCAATACGTGACAAGTGAGGGGTGAGCCAG
GATTCAATACGTGACCAGTGAGGGGCGAGCCAGGATTCGATACGTGACCAGTGAGGGGCGAGCCAGGATGCGATACGTGACCAGTGAGGG
GCGAGCCAGGATTCCATACGTGACTAGTGAGGGGTGAGCCAGGATTCGATATGTGAGTAGTGAGGAGTGAGCCAGGATTTGATATGTGGC
TACTGAGGGGCGAGCCAGGATTTGATATGTGACTAGTAAGGGGTCAGCCAGGATTTGATACGTGACTAGTCAGGGGGTCAGCCAGGATTC
GATACGTGACTAGTAAGGGGTCAGCCAGGATTTGATATGTGACTAGTGAGGGGTGAGCCAGGATTTGACATGTGACTAGTGAGGGGTGAG
CCAGGATTCAATATGTGACTAGTGAGGGGTGAGCCAGGATTCGATATGTACCTAGTGAGGGGTCAGCCAGGATTTGATATGTGGCTAGTA
AGGGGTGAGCCAGCCAGGATTTGATATGTGACTAGTGACGAGTGAGCCAGGATTTGATATGTGACTAGTAAGGGGGTGAGGCAGGATTTG
ATATGTGACTAGTAAGGGGGTGAGGCAGGATTTGATATGTGACTGGTGAGGGGTGAGACAGGATTTGATATGTGACTAGTGAGGGGTGAG
CCAGGATTTGCTATGTGACTAGTAAGGGGGCGAGCCAGGATTTGGCTCCAGCCTTCATTCCAACATCCATGCCTTTTGTACTTCACCAGC
AGTTTTCAAATTTATGGGACAAAATTTTACATTGGATTCCCTCTATACAAAATAGATAAAAGTATTTTATGAATACATTTTATGAGTTCA
AATATTTTTCAGAAGAAATCAGTAAAAGCATTGAAAACTATTCCAGCAAATAGGAAGCACTTTAAACCAAGGTTATGGATGAAAATGTGT
GTGTATCAACCCCAGTTTACTTCTGGGTTGCACAGAATAGAGAAATCTTGATTTAATCCAGCTAAGAATTTTCAAATAGTATCCATTTTG

>60237_60237_1_NRD1-VPS53_NRD1_chr1_52258048_ENST00000352171_VPS53_chr17_440416_ENST00000437048_length(amino acids)=1151AA_BP=941
MLRRVTVAAVCATRRKLCEAGRELAALWGIETRGRCEDSAAARPFPILAMPGRNKAKSTCSCPDLQPNGQDLGENSRVARLGADESEEEG
RRGSLSNAGDPEIVKSPSDPKQYRYIKLQNGLQALLISDLSNMEGKTGNTTDDEEEEEVEEEEEDDDEDSGAEIEDDDEEGFDDEDEFDD
EHDDDLDTEDNELEELEERAEARKKTTEKQSAAALCVGVGSFADPDDLPGLAHFLEHMVFMGSLKYPDENGFDAFLKKHGGSDNASTDCE
RTVFQFDVQRKYFKEALDRWAQFFIHPLMIRDAIDREVEAVDSEYQLARPSDANRKEMLFGSLARPGHPMGKFFWGNAETLKHEPRKNNI
DTHARLREFWMRYYSSHYMTLVVQSKETLDTLEKWVTEIFSQIPNNGLPRPNFGHLTDPFDTPAFNKLYRVVPIRKIHALTITWALPPQQ
QHYRVKPLHYISWLVGHEGKGSILSFLRKKCWALALFGGNGETGFEQNSTYSVFSISITLTDEGYEHFYEVAYTVFQYLKMLQKLGPEKR
IFEEIRKIEDNEFHYQEQTDPVEYVENMCENMQLYPLQDILTGDQLLFEYKPEVIGEALNQLVPQKANLVLLSGANEGKCDLKEKWFGTQ
YSIEDIENSWAELWNSNFELNPDLHLPAENKYIATDFTLKAFDCPETEYPVKIVNTPQGCLWYKKDNKFKIPKAYIRFHLISPLIQKSAA
NVVLFDIFVNILTHNLAEPAYEADVAQLEYKLVAGEHGLIIRVKGFNHKLPLLFQLIIDYLAEFNSTPAVFTMITEQLKKTYFNILIKPE
TLAKDVRLLILEYARWSMIDKYQALMDGLSLESLLSFVKEFKSQLFVEGLVQGNVTSTESMDFLKYVVDKLNFKPLEQEMPVQFQVVELP
SGHHLCKVKALNKGDANSEVTVYYQSGTRSLREYTLMELLVMQWQNVEHVGDQSPYVTSVILHIKQNVPIIRDNLASTRKYFTQFCVKFA
NSFIPKFITHLFKCKPISMVGAEQLLLDTHSLKMVLLDLPSISSQVVRKAPASYTKIVVKGMTRAEMILKVVMAPHEPLVVFVDNYIKLL

--------------------------------------------------------------
>60237_60237_2_NRD1-VPS53_NRD1_chr1_52258048_ENST00000354831_VPS53_chr17_440416_ENST00000437048_length(transcript)=14310nt_BP=3217nt
AGTAGCGTCATCGGCGGCCGGGAGGGCGGAGGGACGAGGGAAGTCGGCGAGAGGGAGACTGGGTTGGGGGAGGGGTTCAGGCCTGTTCCC
CGCGGCTGCGGCAGCACCAGGGCCGGCCGCCACCGCCTCTAGAACGCGGAGGAGGTGGGTCCTGGGAAGCGGGATGTCCATCGCTCCAGC
TTGGTGGTGAATGCTGAGGAGAGTCACTGTTGCTGCAGTCTGTGCCACCCGGAGGAAGTTGTGTGAGGCCGGGCGGGAGCTCGCGGCGCT
CTGGGGAATCGAAACGCGGGGTCGGTGCGAAGACTCTGCTGCTGCCAGACCCTTTCCTATTCTGGCCATGCCTGGAAGGAACAAGGCGAA
GTCTACCTGCAGCTGCCCTGACCTGCAGCCCAATGGACAGGATCTGGGCGAGAACAGCCGGGTTGCCCGTCTAGGAGCGGATGAATCTGA
GGAAGAGGGACGGAGGGGGTCTCTCAGTAATGCTGGGGACCCTGAGATCGTCAAGTCTCCCAGCGACCCCAAGCAATACCGATACATCAA
ATTACAGAATGGCTTGCAGGCACTTCTGATTTCAGACCTAAGTAATATGGAAGGTAAAACAGGAAATACAACAGATGATGAAGAAGAAGA
GGAGGTGGAGGAAGAAGAAGAAGATGATGATGAAGATTCTGGAGCTGAAATAGAAGATGACGATGAAGAGGGTTTTGATGATGAAGATGA
GTTTGATGATGAACATGATGATGATCTTGATACTGAGGATAATGAATTGGAAGAATTAGAAGAGAGAGCAGAAGCTAGAAAAAAAACTAC
TGAAAAACAGCAATTGCAGAGCCTGTTTTTGCTGTGGTCAAAGCTGACTGATAGACTGTGGTTTAAGTCAACTTATTCAAAAATGTCTTC
AACCCTGCTGGTCGAGACAAGAAATCTTTATGGGGTAGTTGGAGCTGAAAGCAGGTCTGCACCTGTTCAGCATTTGGCAGGATGGCAAGC
GGAGGAGCAGCAGGGTGAAACTGACACAGTTCTGTCTGCAGCGGCTCTTTGTGTTGGAGTTGGGAGTTTCGCTGATCCAGATGACCTGCC
GGGGCTGGCACACTTTTTGGAGCACATGGTATTCATGGGTAGTTTGAAATATCCAGATGAGAATGGATTTGATGCCTTCCTGAAGAAGCA
TGGGGGTAGTGATAATGCCTCAACTGATTGTGAACGCACTGTCTTTCAGTTTGATGTCCAGAGGAAGTACTTCAAGGAAGCTCTTGATAG
ATGGGCGCAGTTCTTCATCCACCCACTAATGATCAGAGATGCAATTGACCGTGAAGTTGAAGCTGTTGATAGTGAATATCAACTTGCAAG
GCCTTCTGATGCAAACAGAAAGGAAATGTTGTTTGGAAGCCTTGCTAGACCTGGACATCCTATGGGAAAATTTTTTTGGGGAAATGCTGA
GACGCTCAAGCATGAGCCAAGAAAGAATAATATTGATACACATGCTAGATTGAGAGAATTCTGGATGCGTTACTACTCTTCTCATTACAT
GACTTTAGTGGTTCAATCCAAAGAAACACTGGATACTTTGGAAAAGTGGGTGACTGAAATCTTCTCTCAGATACCAAACAATGGGTTACC
CAGACCAAACTTTGGCCATTTAACGGATCCATTTGACACACCAGCATTTAACAAACTTTATAGAGTTGTTCCAATCAGAAAAATTCATGC
TCTGACCATCACATGGGCACTTCCTCCTCAACAGCAACATTACAGGGTGAAGCCACTTCATTATATATCCTGGCTGGTTGGACATGAAGG
CAAAGGCAGCATTCTTTCTTTCCTTAGGAAAAAATGCTGGGCTCTTGCACTGTTTGGTGGAAATGGTGAGACAGGATTTGAGCAAAATTC
TACTTATTCAGTGTTCAGCATTTCTATTACATTGACTGATGAGGGTTATGAACATTTTTATGAGGTTGCTTACACTGTCTTTCAGTATTT
AAAAATGCTGCAGAAGCTAGGCCCAGAAAAAAGAATTTTTGAAGAGATTCGGAAAATTGAGGATAATGAATTTCATTACCAAGAACAGAC
AGATCCAGTTGAGTATGTGGAAAACATGTGTGAGAACATGCAGCTGTACCCATTGCAGGACATTCTCACTGGAGATCAGCTTCTTTTTGA
ATACAAGCCAGAAGTCATTGGTGAAGCCTTGAATCAGCTAGTTCCTCAAAAAGCAAATCTTGTTTTACTGTCTGGTGCTAATGAGGGAAA
ATGTGACCTCAAGGAGAAATGGTTTGGAACTCAATATAGTATAGAAGATATTGAAAACTCTTGGGCTGAACTGTGGAATAGTAATTTCGA
ATTAAATCCAGATCTTCATCTTCCAGCTGAAAACAAGTACATAGCCACGGACTTTACGTTGAAGGCTTTCGATTGCCCGGAAACAGAATA
CCCAGTTAAAATTGTGAATACTCCACAAGGTTGCCTGTGGTATAAGAAAGACAACAAATTCAAAATCCCCAAAGCATATATACGTTTCCA
TCTAATTTCACCGTTGATACAGAAATCTGCAGCAAATGTGGTCCTCTTTGATATCTTTGTCAATATCCTTACGCATAACCTTGCGGAACC
AGCTTATGAAGCAGATGTGGCACAGCTGGAGTATAAACTGGTAGCTGGAGAACATGGTTTAATTATTCGAGTGAAAGGATTTAACCACAA
ACTACCTCTACTGTTTCAGCTCATTATTGACTACTTAGCTGAGTTCAATTCCACACCAGCTGTCTTTACAATGATAACTGAGCAGTTGAA
GAAGACCTACTTTAACATCCTCATCAAGCCCGAGACTTTGGCCAAAGATGTACGGCTTTTAATCTTGGAATATGCCCGTTGGTCTATGAT
TGACAAGTACCAGGCTTTGATGGACGGCCTTTCCCTTGAGTCTCTGCTGAGCTTCGTCAAAGAATTCAAATCCCAGCTCTTTGTGGAGGG
CCTGGTACAAGGGAATGTCACAAGCACAGAATCTATGGATTTCCTGAAATATGTTGTTGACAAACTAAACTTCAAGCCTCTGGAGCAGGA
GATGCCTGTGCAGTTCCAGGTGGTAGAGCTGCCCAGTGGCCACCATCTATGCAAAGTGAAAGCTCTGAACAAGGGTGATGCCAACTCTGA
AGTCACTGTGTACTACCAGTCAGGTACCAGGAGTCTAAGAGAATATACGCTTATGGAGCTGCTTGTGATGCAGTGGCAGAACGTGGAGCA
CGTTGGTGACCAGAGCCCCTACGTCACCTCTGTCATTCTGCACATCAAGCAGAACGTCCCCATCATCCGTGACAACCTGGCTTCCACACG
CAAGTACTTCACTCAGTTCTGCGTTAAATTTGCAAACTCCTTCATTCCCAAATTCATCACCCACCTCTTCAAGTGCAAGCCAATTAGCAT
GGTGGGAGCAGAACAGCTGCTGCTGGACACCCACTCGCTGAAGATGGTCCTGCTCGATCTCCCCTCCATCAGCTCGCAGGTGGTGAGGAA
GGCACCCGCCAGCTACACCAAGATCGTTGTCAAAGGCATGACCCGGGCTGAGATGATCCTCAAGGTAGTGATGGCCCCTCATGAACCGTT
GGTGGTGTTTGTTGACAACTACATCAAACTTCTCACAGACTGCAACACAGAAACCTTTCAGAAGATACTGGACATGAAGGGGCTGAAGAG
GAGTGAGCAGAGCAGCATGCTGGAACTCCTGCGCCAGCGGCTCCCCGCACCGCCCTCGGGGGCAGAAAGCTCCGGCTCACTGTCCCTGAC
GGCGCCAACACCAGAGCAAGAGTCGTCACGCATCCGCAAGCTCGAGAAACTCATTAAAAAGAGACTGTAGCAGCAGCAAGGGGCCCTTTG
CTCCTGGCTGGAGACCCTCAGCGCCCGTTCCCCAGAAGCCCCCAACCTCTCCTGTGCTCCCCGGCACTCTCACATCGTCGGTCTTCAAAC
TTCCTGGGACATGTGGGTTGTTACTGAGTCTCTCCCATGCCCTGTCTTACTTCCTGCCCTAATCGGAGACGCTGAGTAAGGGCTGGGCTC
TAAGAGGGCGATTTAGGTGATCTCTGGTTCGTGAAGCAGAGGCAGCAGTGGAGGATAGGTCCCTGAGCTGCCCTTGACTCATGTAGCCTC
CCCATGGCAGTCACACCCTCTTGACACGTGGGCCCCACCCGTCCTTTTTTTTTTTTTTTTTTTTTTTTTTTGAGACAGAGTCTCGCTCTG
TCACCCAGGCTGGAGTGCAGTGGCGTGATCTCGGCTCACTGCAACCTCCGCCTCCCAGGTTCAAGCAATTCTCCTGCCTCAGCCTCCTGA
GTATCGGATTACAGGCGTGAGCCACCGAGCCCAGCCCCTTCCTCCATTTCTTTACTCCCACCCTGCTCCTGGTTTCTAGGGAAGGGAAAC
CAGGAAGTTCACTTGGAAGACGTTTCCTAGGTTTTCTCATCAGATGAAGCCATGGGAACGCCCAGGAAGTCCATACTCTCAAACCCCTTT
CTGCCCACTCACCTTCAGGTCCACAGCACTTTCCAGCGTCATCTGAAATAGCAAAGGTGATGTGCAGCATCCCAGTGATGTGTTCCTGTG
TTATGAGAAGGAGTCTGGGGTTCTGGATGCCTCAGGAACAGAATATGGACCTTAAAGACCAGGCTGAGAGCCTGGCCTGGCACGCAGCCT
GCCCGCCCCCCCCGCCCTTCCTGTCCACCGCGGGCTCTCTGCAGCAGGGCTTGCCGAAGAGACTGCTCCCGACCTCTCATGTCATCCTGC
ATCCAGAGAATGGCAGCATATCAAGCCGTTAACCCTGATTCACTCGGTTCCCTTGAAACCAGGCCTCAGTTAACCATGACCACAGCTACA
GGCAAACCGCTGCTGTTGCTGCCTGCTTTTGCTGAAGAATGATATCTTGCCAGGCACGGCGGCTCATGCCTGTAGTCGCAACACTTTGGG
AGACCAAGGCAGGAGGATCACTTGAGTCCAGGAGTTTGAGACCAGCCTGGGCAACATACAGATGTCTACAAAAATAAAAATTTGCAAGGT
GTGGTGGCATGCACCTGTAGTCCCAACTGCTAGGGAGGCTGAGGTGGGCAGATTGCTTGAGCTCAGGAGTTTGAGACCAGTCTGGGCAAC
CTGGCAAAACCAAAAATACAAAAAATTGGCTGGGTGTGGTGGCTCATGCCTGTAATCACAGCACTTTGGGAGGCTGAGGCAGGTGGATCA
CCTGAGGTCAGGAATTCGAGACCAGCCTGCCCAACATGGCGAAACCCTGTCTCAACTAAAAATAAAAAAAATTAGCCGGGTGTCATGGCG
AGTGCCTGTAATCCCAGCTACTGGGGAGGCTGAGGCAGGAGAATCACTTAAACCCGGGAGGTGGAGGCTGCAGTGAGCCAAGATTTCACC
ACTGCACTCCAGCCTGGGTGACAGAGCAAGACCCCTTCTCAAAAAGTTTTCAGGATAGAGGAAATTTCCTTAAAATCCATAAAACTTGTA
ACAGCCGTACAGTAGGAATAAGGTTTGGAAATCTGCCTGGAAACCTGATTTCCTCATCCCCACCTTGTTTCCCAACATAACCACTGCTCT
GTGCCCCTGCCCTCTCTGCCAGGCTTTCTCCCCGATGCCGTCCAGCTCTGATCCTGAGTGTCATTTCTTCATCGGCTTCCAGGCTGTCCT
TGCTAGCTGGTTTGACTCTCACGCATCAAGCGTCTCAAATTTGAGAATGCGGAGGAGAAAAGAAGTGTTGCGAGAAGGAGATGCGGCCTT
CAGTTGAGGTCTATTAGGAAAAGATTCCAAATAAGACAAGGGCGGGGGGCGGCAGTCGGGAGAGCCCCCAGGAAGCCCTGTAGATGCCCC
CACCCCAGCCCATGGAGTTGCTATGGTTAAGCAGCCTGAGCCGTACAGTTGAAAAGGGGCGGTGGGGCCCATCTCCAAATAGCACAGCCA
GTTCAGCCGTCTGTCCTCAACCCAGGAGAGCTGGGAAAGCCAGTGGACTCCTGCACCTGGTTCTTGTCACTCCTGGCGTTTGTGTACAGA
TCACCACTTCTCTTTTTGGTTCATTGTTGAGGAGTCGTTTTCCGGACGGCTCCATCACAGCATTGAGCTATCAAGCTGCTGTTTTCCACA
GTTGGTGGTCACAGCCAGGGAAGTTGCTGTCTTGATTTGTTACATTGTCAGTAATCCCCAAGGAACCAATGGATGTCAGTAGGAGTTTCT
GTTAAATGTCTCCTTGATGGGGACTCAGTACTGTGTAGAGACGCTGTGTTTCTCTTCTGGGGGTGTGCATCAGAACCACTGGGGCCTTTT
AAAATCTACAGATGCCGGCCGGGCGCCGTGGCTCACGCCTGGAATCCCAGCACTTGGGGAGGCTGAGGCGGGCGGATCACAAGCGCAGGA
AATTGAGACCATCCTTGCCAATATGGTGAAACCCCATCTCTACAAAAAATACAAAAATTACCGGGGTGTGGTGGCGTGCACACCTCCCAG
CTACTTGGGAGGCTGAGGCAGGAGAATCGCTTGAACCCGGGAGGCAAAGATTGCAGTGAGCCGAGATCACGCCACTGCACTCCAGCCTGG
CGACAGAGTGAGACTCTATCTCAAAACAAACAAAAAAACAGATGCCCGGAGATTTTGAGTCAGTAAGTTTGGATGGGGCCTGGCATACAG
GTTTAAAAGTTCCATAGGTAGTTATAACGTTTACACCTTGTTAAGAACCACTGCAACAGAGAGATTTGCTTTATGGAAGGGCTCCTGCCA
CGCATTTTCATACATGTCTATTTTTCTGACTCTAAGCTAAAAGTGCGCCGACACTACACTTGAGCTGGTGCCAACGTGGTGAAGATTCTC
TACTGATAACAGCTTTCATTTTAAACTTGTGTTGGGTCAGGCGCGGTGGCTCACGCCTGTAATCCCAGCACTTTGGGAGGCCGAGGTGGG
CGGATCACATGAGGTCACGAGTTTGAGACCAGCCTGGCCAACATGGCAAAATCCCATCTCTACTAAAAATACAAAAAAAAAAAAAAAAAA
AGCAGGCAGGTGGCGGGTGCCTGTAATCCCAGCTACTTGGGAGGCTGAGGCAGGGGAATCAGTTGAATCCGGGAGGCGGAGGTTGCAGTG
AGCCGAGGTCCCGCCACTGCACTCCAGCCTGGGAGACAGAGTGAGACTCAGTTAAAAAAAAAAGACTTTTGGTGGTGGTGGGGACCATGC
CCAGGATTGGGCTCTCTCCATACTGATGAGGATTCTTCTTGTTTTGATGACCAACCCCCAAGCAGAAGCTTTATTTATTAACATCACTTC
AAAAATAACGTATCAAAGGGGCACCCTAGGCCGGGTACTGTGGCATCACACCTGTAATGCCAGTGCTTTGAGAGGCTGAGGTGGGAAGAT
TGCTTGAGCCCAGGACTTCAAGACAAGCCTGGGCAACAGAGTGAGACCCCATCTCTATTAAAAAATAGGCCGGGCATGGTGGCTCACACT
GGTAATCCCAGCACTTTGGGAGGCCGAGGCAGGTGGATCATGTGAGGTCAGGAGTTCGAGACCAGCCTGGCCGACATGGTGAAACCCTGT
CTTTACTAAAAATACAAAATTAGCCAGGCGTGGTGGTGGGCGCCTGTAATCCCAGCTACTCAGGAGGCTGAAGCAGGAGGATCGCTTGAA
CCCAGGAGGCAGAGGCTGCAGTGAGCCGAGATCATGCCATTGCACTCCTGCCTGGGTGACGGAGCAAGACTCTCTAAAAAATAATAAGGT
AAAAGGAGTACCTGTGGATGAAAGCAGCAGCTAACAGCTCTGTGATTCAGCTAGACCTAGATATTGTGCCCATTCCTTCCCCTCAGTCCA
TTTTCTGTAGCCCCTTTAAAAACCAAAAAACAACTTTGAAGTCACTTTGGGTTTAAAATAAATAGTGGTAATTTGTATAATCAATAAAGA
GTTCACTCTGCTCTTACTGAGGGGACTTGTCTGAAAGCTGGCTTAGCGGTGTCCAGGCCAGAGAACATCCTGTGTGGACTCTTAACAATG
AAACAGGAGCCGCAATGGACAAGGTGTTCTGATCTCCAAACCCAGCTCAGGGATTGAAGCTAACTACCGCCACTCCTTCCTCTCTCGAAG
AACAAAGAGCCAGTACCCAGGGCTCTGCCCACCCCCGAGAAGGGGTGCCTGATTTCTTATGTCTAGGGTGGCTCCTCTGTGCAGATCAGA
CAGGACTGAGAGCAGACAAGCTGAGACCAGCATGACCAGTACAGGGCACGCAGAGCGTGGGGGCAGGTCCGAGGCTGCTGCTCGATGCAG
GGTATGACACCAACCCTTCCTGAATTGCCATCGGATGAGGAGACCTGGTTCCCTGTTGAAAGAATGCCAGGGGAAATGCTGCATGTGCAC
AGCTGGAAATGGGGTTCCTTCTCTAGGAAGAGCACTCGGAATAACCTGCTGGAAATGGGGTTCCTTCCCTAGGAAGAGCACTCAGAATAA
CCTGCTGGAAATGGGATTCCTTGGCTAGGAAGAGCACTCAGAATAACCTGCTGGAAATGGGATTCCTTGGCTAGGAAGAGCACTCAGAAT
AACCTGCTGGAAATGGGATTCCTTACCTAGGAAGAGCACTCGGAATAACCTGCTGGAAATGGGATTCCTTACCTAGGAAGAGCACTCGGA
ATAACCTGCTGGAAATGGGGTTCCTTCCCTAGGAAGAGCACTCGGAATAACCTGCTGGAAATGGGGTTCCTTCCCTAGGAAGAGCACTCG
GAATAACCTGCTGGAAATGGGGTTCCTTCGCTAGGAAGAGCACTCGGAATAACCTGCTGGAAATGGGATTCCTTCGCTAGGAAGAGCACT
CGGAATAACCTGCTGGAAATGGGATTCCTTCGCTAGGAAGAGCACTCGGAATAACCTGCTGGAAATGAGATTCCTTCCCTAGGAAGAGCA
CTCGGAATAACCTGCTGGAAATGGGATTCCTTCGCTAGGAAGAGCACTCGGAATAACCTGCTGGAAATGAGATTCCTTCGCTAGGAAGAG
CACTCGGAATAACCTGCTGGAAATGGGATTCCTTCGCTAGGAAGAGCACTCGGAATAACCTGCTGGAAATGAGATTCCTTCGCTAGGAAG
AGCACTCGGAATAACCTGCTGGAAATGGGATTCCTTCGCTAGGAAGAGCACTCGGAATAACCTGCTGGAAATGGGATTCCTTCGCTAGGA
AGAGCACTCGGAATAACCTGCTGGAAATGGGATTCCTTCCCTAGGAAGAGCACTCGGAATAACCTGCTGGAAATGAGATTCCTTCCCTAG
GAAGAGCACTCGGAATAACCTGCTGGAAATGGGATTCCTTCGCTAGGAAGAGCACTCGGAATAACCTGCTGGAAATGGGATTCCTTCGCT
AGGAAGAGCACTCAGAACAACCTGCCTGCTTGAGGGTGACAGCAAGTGTCTCACACTTCTCGTCTACTCCAAGTCAGATTCCTAAAAATA
AAATAGAGCTCCAATGGGCAATTTAAGCAAAAGCCTTAGAAACATGGACACCTGAAATGCTGGCCTACATGAAGGGTACGATGACATTTT
ATATATTAAATAAAAATTCCCAGTCCTGTTTTAGTATTCATCAGAATAGCCTCTTGGACCCTCGAAGTTCTACACCTTTGGGAGATATAA
ATTTCCTTAAAATAAAGGGATTGCTTCTTTGTGTAAATAGCTTTCATTTTCTCCATCTGGAAGTGATTTCTGCCTGCATGTTGGAGCACA
AAATACTGCAGTTAATTAAAGCATTACTGGATGTCATTTGCTAGAATGTATTTCCTTACTGCTGACAGAAAACAGAACAGACTCTAGGAA
AGAAGTAGCAAGTCCGTGACCCTGGCCGCTCCTGGTGGCTGCCCTTCTCCCTTCCCTGACAGTCTAAGGAAGCAACGCGTGGGAGCAGAA
TGTGGCCGACTGAGCCCAGTCCTGACCTGCCCAGTTGCAGTGGAGCCTGTCTGTAATGTTGTGTAAAGTGTTTTGCTTCTGACTTGGAAC
CCTACTTGCCCTGTGAATTTCTATCCTGTGAACCTTCCCTTCTCTGTCCTTACCGTTCCCATCACAGCCTGCTCTTCCAGTGACGGCCAA
GTGATTTCTCTCCTGCACGCATGAGTCCATCCTGTTTCCTTAGTAGCTGGATGGACGTTTTGCCATGAAAACTCTTTGGGAAGTCTTGTG
TCCTTTAGTGATTTCTCTCCTGCACGCATGAGTCCATCCTGTTTCCTTAGTAGCTGGTTGGACGTTTTTGCCATGAAAACTCTTCGGGAA
GTCCTGTGTCCTTTCAACAGGGGAAAACTGGCTGCGGCCCTTCCATTAGGCTCCAGGATCATTACCTCGTTTCCATTCTTTCTTTTCAAC
AGCTCCCCACTTTACTAGGGAAGCCAAGGGATCAACCTAATGAGAAAAGAACCTTCCCTGTAGCCCACCTGGAAGGGCATTGCCTGCCAG
CTCCTTCCTTCTCACCTATGTGAACAGGAGGGAAGATGCCGGCGATCCATGGATCTGTGGGACATGAAGGACGTGTCCATCAGAAATGAA
AGCAGCCTGGGATTGGAAGCATCCACAGAAGACTTGATCTGCAGGTCTTGATTTGGACCTGGCACTTTGACACCAGGCGAGTCACTGATC
CCCTGAGCATCCATTTTCAATATTGGTGAGAGGGGATTATAATGAATATTGGCTGTGAAGGTCACACAAGACCGGGCTATATGCACTTGC
TCTGCCATAAGGCAGTGTGAAGTGTGTTCGTGATCACTTGTGGGCGGGAGCCTGTGGCTGTCTTGCCTGGACTGGCTTTTTTAAACATGG
ATGAGTGGTGACAAATCCTGCGGCCGTGTGCAGGCTACATCCGCAGCGAGCTCCGCATATCTGGTCTTTGCCTTTTTAGGTCATGACTGT
AATATCAAGCTTACACGAGAGTTTTAAAAGACTGAGCAGTATCCCCTTCCCCTGGCAGCTGCTGCTTCCGTAGCATTTAGGGATAAACCT
GCAGACACTGAGAAGAGAGCTTCCTCCCTCCTGGGGCTGGTGGCGAGGCTGCCTGTTGTGGAAAATAGGGCATGTCTCCTGTGAATGCGA
ATTGCGAGGGTTGCCAAAGCCTCCCTTCCAAGAAACTTGCTTAGGTGTCTGGTGTCCACAGACCAGACTCTTCTCCCGACAGGGACAAAA
ATTCTTGCCTGCCTTTCTTTTTCTTTTTTTTCCTTTTACTTATTCTTGCCTTTTTTCTTCTTCTTCTTCTTTAGGTATGATGCCCCCCAA
AAAACTAAGCAAGATTAACTTGGGACAGGCAGTTCTAACTGGGAAGCCTGAGCTCACAGGCTGTTTGGATTACTTTCCAATTGTGTTTCA
AAGATGTTTAGACTTTTCCCAAGGCCAGCTGAATCCTTATAATCAGCCCAAAAGTTCCTTTCTGTTTCTGTCTGTCCCCTTTGAGGGTGT
TGACTCAGAGAACCTGGGGCAATATGAGATGTTAAAATAAAAATAGCGTCCAACGTCCCGCCTCCTGGGAATGCTGCTCACTTCATCCGA
GGGTTCTGGGAGCTTCTGCTCAGTCATCAAATGGAATTTGCACAATTGTCTTGCCTCCTGTTTTGGGTAATTTTTCAACAAGTGAGAAAT
TAAGAACAGCTTCTCAACAAACTTCCCTCTACTTCCAGGGCCAAGAAAAGTATTTGCAGTGTGGGCTGCAGCTTTCAGGGGTCTCAGGTG
AAATGGTGGCAAGAAACCCCAGCTCCCTTCATGTGTTTGCCTTGCGCTGATGGAAAAGGAAGGCACTTCTCAGCTGCCAGAGACCACATT
CCACAGGGTTCTTCACAAAATCAAGCACTGCAGTGGACCAACTGGAGCAGCCACTGGAGGGCTTTAGAAGGCAAATGGAATACATATCAA
ATGCTATATAAAGAAAACATCTGTTTACACAGAGTCCCCCACAGCCTCATACCTACACCCAATATCAAATGCTGTATAAAGAAACATCAG
TTTACACACAGAGCCCCCCACAACCTCATACCCACACCGAATATCAAATGCTATACAAAGAAACATCAGTTTACACACAGAGTCCCCCAC
AGCCTCATACCCATGCCTGTCACATCTTTGCACAGCCCTAAAGGATCCAGAGCTTTGGATCAGCAGCTGGCTAGCTCGGAGGCCAGAGGA
GGGTGCTGAGGGGAGTGGAGGTCAGTTGGGGTAGCCCTGGGCCCTGGCTGCACAGTCCAGCTGCTGTGTGGCCTGCATGTGGTATCTTAG
GTCATGAGAGGGCCTGGGCAATTCAGTGCTATCTGTACATGTTGGTGGGGTGGGAAGGAAAAGGTAACTGTGTATTTACTGTGTCCTGGA
TACATTATCTCATCGGATGAAATTCCTGCTAAGTTAAGCTCCGTTTAGTGGACGGGACTTGGAGGCTCAAAGAGGGTAAGTGACAGGCCC
AAGGATATGTGCCTAGTGAGGGGTGAGCCAGGATTCGATGTGTGACTAGTAAGGGGTCAGCCAGGATTCAATATGTGACTAGTAAGGGGT
CAGCCAGGATTTCATATGGGACTAGTAAGGGGTCGGCCAGGATTTGATACGTGACTAGCAAGGGGACAAGCCAGGATTTGATATGTGACT
AGTGAGGGGCGAGCCAGGATTCGATATGTGACTAGTAAGGGGTCAGCCAAGATTTGATATGTGACTAGTGAGGGGCGAGACAGGATTTGA
TATGTGACTAGTGAGGGGCGAGCCAGGATTTGATATGTGACTGGTGAGGGGCGAGCCAGGATTTGATATGTGACTGGTGAGGGGCGAGCC
AGGATTTGATATGTGACTGGTGAGGGGCGAGCCAGGATTTGATATGTGACTGGTGAGGGGCGAGCCAGGATTTGATATGTGACTGGTGAG
GGGCGAGCCAGGATTTGATATGTGACTGGTGAGGGGCGAGCCAGGATTTGATATGTGACTGGTGAGGGGCGAGCCAGGATTTGATATGTG
ACTGGTGAGGGGCGAGCCAGGATTTGATATGTGACTGGTGAGGGGCGAGCCAGGATTTGATATGTGACTGGTGAGGGGCGAGCCAGGATT
TGATATGTGACTGGTGAGGGGCGAGCCAGGATTTGATATGTGACTGGTGAGGGGTGGAGCCAGTCAGGATTTGATATGTGGTTAGTGAGG
GGTTAGCCAGTCAGGATTTGATATGTGGCTAGTGAGGGGCGAGCCAGGATTTGATATGTGACTAGTAAGGGGGTGAGCCAGGATTCAATA
CGTGACAAGTGAGGGGTGAGCCAGGATTCAATACGTGACCAGTGAGGGGCGAGCCAGGATTCGATACGTGACCAGTGAGGGGCGAGCCAG
GATGCGATACGTGACCAGTGAGGGGCGAGCCAGGATTCCATACGTGACTAGTGAGGGGTGAGCCAGGATTCGATATGTGAGTAGTGAGGA
GTGAGCCAGGATTTGATATGTGGCTACTGAGGGGCGAGCCAGGATTTGATATGTGACTAGTAAGGGGTCAGCCAGGATTTGATACGTGAC
TAGTCAGGGGGTCAGCCAGGATTCGATACGTGACTAGTAAGGGGTCAGCCAGGATTTGATATGTGACTAGTGAGGGGTGAGCCAGGATTT
GACATGTGACTAGTGAGGGGTGAGCCAGGATTCAATATGTGACTAGTGAGGGGTGAGCCAGGATTCGATATGTACCTAGTGAGGGGTCAG
CCAGGATTTGATATGTGGCTAGTAAGGGGTGAGCCAGCCAGGATTTGATATGTGACTAGTGACGAGTGAGCCAGGATTTGATATGTGACT
AGTAAGGGGGTGAGGCAGGATTTGATATGTGACTAGTAAGGGGGTGAGGCAGGATTTGATATGTGACTGGTGAGGGGTGAGACAGGATTT
GATATGTGACTAGTGAGGGGTGAGCCAGGATTTGCTATGTGACTAGTAAGGGGGCGAGCCAGGATTTGGCTCCAGCCTTCATTCCAACAT
CCATGCCTTTTGTACTTCACCAGCAGTTTTCAAATTTATGGGACAAAATTTTACATTGGATTCCCTCTATACAAAATAGATAAAAGTATT
TTATGAATACATTTTATGAGTTCAAATATTTTTCAGAAGAAATCAGTAAAAGCATTGAAAACTATTCCAGCAAATAGGAAGCACTTTAAA
CCAAGGTTATGGATGAAAATGTGTGTGTATCAACCCCAGTTTACTTCTGGGTTGCACAGAATAGAGAAATCTTGATTTAATCCAGCTAAG
AATTTTCAAATAGTATCCATTTTGTTTTGTTTTAAACAGCTCTTCTTGCAATGGTAGAGGCTCTTCAATTAAACAGAGATGGTAACAGGC

>60237_60237_2_NRD1-VPS53_NRD1_chr1_52258048_ENST00000354831_VPS53_chr17_440416_ENST00000437048_length(amino acids)=1219AA_BP=1009
MLRRVTVAAVCATRRKLCEAGRELAALWGIETRGRCEDSAAARPFPILAMPGRNKAKSTCSCPDLQPNGQDLGENSRVARLGADESEEEG
RRGSLSNAGDPEIVKSPSDPKQYRYIKLQNGLQALLISDLSNMEGKTGNTTDDEEEEEVEEEEEDDDEDSGAEIEDDDEEGFDDEDEFDD
EHDDDLDTEDNELEELEERAEARKKTTEKQQLQSLFLLWSKLTDRLWFKSTYSKMSSTLLVETRNLYGVVGAESRSAPVQHLAGWQAEEQ
QGETDTVLSAAALCVGVGSFADPDDLPGLAHFLEHMVFMGSLKYPDENGFDAFLKKHGGSDNASTDCERTVFQFDVQRKYFKEALDRWAQ
FFIHPLMIRDAIDREVEAVDSEYQLARPSDANRKEMLFGSLARPGHPMGKFFWGNAETLKHEPRKNNIDTHARLREFWMRYYSSHYMTLV
VQSKETLDTLEKWVTEIFSQIPNNGLPRPNFGHLTDPFDTPAFNKLYRVVPIRKIHALTITWALPPQQQHYRVKPLHYISWLVGHEGKGS
ILSFLRKKCWALALFGGNGETGFEQNSTYSVFSISITLTDEGYEHFYEVAYTVFQYLKMLQKLGPEKRIFEEIRKIEDNEFHYQEQTDPV
EYVENMCENMQLYPLQDILTGDQLLFEYKPEVIGEALNQLVPQKANLVLLSGANEGKCDLKEKWFGTQYSIEDIENSWAELWNSNFELNP
DLHLPAENKYIATDFTLKAFDCPETEYPVKIVNTPQGCLWYKKDNKFKIPKAYIRFHLISPLIQKSAANVVLFDIFVNILTHNLAEPAYE
ADVAQLEYKLVAGEHGLIIRVKGFNHKLPLLFQLIIDYLAEFNSTPAVFTMITEQLKKTYFNILIKPETLAKDVRLLILEYARWSMIDKY
QALMDGLSLESLLSFVKEFKSQLFVEGLVQGNVTSTESMDFLKYVVDKLNFKPLEQEMPVQFQVVELPSGHHLCKVKALNKGDANSEVTV
YYQSGTRSLREYTLMELLVMQWQNVEHVGDQSPYVTSVILHIKQNVPIIRDNLASTRKYFTQFCVKFANSFIPKFITHLFKCKPISMVGA
EQLLLDTHSLKMVLLDLPSISSQVVRKAPASYTKIVVKGMTRAEMILKVVMAPHEPLVVFVDNYIKLLTDCNTETFQKILDMKGLKRSEQ

--------------------------------------------------------------
>60237_60237_3_NRD1-VPS53_NRD1_chr1_52258049_ENST00000352171_VPS53_chr17_440416_ENST00000437048_length(transcript)=14106nt_BP=3013nt
AGTAGCGTCATCGGCGGCCGGGAGGGCGGAGGGACGAGGGAAGTCGGCGAGAGGGAGACTGGGTTGGGGGAGGGGTTCAGGCCTGTTCCC
CGCGGCTGCGGCAGCACCAGGGCCGGCCGCCACCGCCTCTAGAACGCGGAGGAGGTGGGTCCTGGGAAGCGGGATGTCCATCGCTCCAGC
TTGGTGGTGAATGCTGAGGAGAGTCACTGTTGCTGCAGTCTGTGCCACCCGGAGGAAGTTGTGTGAGGCCGGGCGGGAGCTCGCGGCGCT
CTGGGGAATCGAAACGCGGGGTCGGTGCGAAGACTCTGCTGCTGCCAGACCCTTTCCTATTCTGGCCATGCCTGGAAGGAACAAGGCGAA
GTCTACCTGCAGCTGCCCTGACCTGCAGCCCAATGGACAGGATCTGGGCGAGAACAGCCGGGTTGCCCGTCTAGGAGCGGATGAATCTGA
GGAAGAGGGACGGAGGGGGTCTCTCAGTAATGCTGGGGACCCTGAGATCGTCAAGTCTCCCAGCGACCCCAAGCAATACCGATACATCAA
ATTACAGAATGGCTTGCAGGCACTTCTGATTTCAGACCTAAGTAATATGGAAGGTAAAACAGGAAATACAACAGATGATGAAGAAGAAGA
GGAGGTGGAGGAAGAAGAAGAAGATGATGATGAAGATTCTGGAGCTGAAATAGAAGATGACGATGAAGAGGGTTTTGATGATGAAGATGA
GTTTGATGATGAACATGATGATGATCTTGATACTGAGGATAATGAATTGGAAGAATTAGAAGAGAGAGCAGAAGCTAGAAAAAAAACTAC
TGAAAAACAGTCTGCAGCGGCTCTTTGTGTTGGAGTTGGGAGTTTCGCTGATCCAGATGACCTGCCGGGGCTGGCACACTTTTTGGAGCA
CATGGTATTCATGGGTAGTTTGAAATATCCAGATGAGAATGGATTTGATGCCTTCCTGAAGAAGCATGGGGGTAGTGATAATGCCTCAAC
TGATTGTGAACGCACTGTCTTTCAGTTTGATGTCCAGAGGAAGTACTTCAAGGAAGCTCTTGATAGATGGGCGCAGTTCTTCATCCACCC
ACTAATGATCAGAGATGCAATTGACCGTGAAGTTGAAGCTGTTGATAGTGAATATCAACTTGCAAGGCCTTCTGATGCAAACAGAAAGGA
AATGTTGTTTGGAAGCCTTGCTAGACCTGGACATCCTATGGGAAAATTTTTTTGGGGAAATGCTGAGACGCTCAAGCATGAGCCAAGAAA
GAATAATATTGATACACATGCTAGATTGAGAGAATTCTGGATGCGTTACTACTCTTCTCATTACATGACTTTAGTGGTTCAATCCAAAGA
AACACTGGATACTTTGGAAAAGTGGGTGACTGAAATCTTCTCTCAGATACCAAACAATGGGTTACCCAGACCAAACTTTGGCCATTTAAC
GGATCCATTTGACACACCAGCATTTAACAAACTTTATAGAGTTGTTCCAATCAGAAAAATTCATGCTCTGACCATCACATGGGCACTTCC
TCCTCAACAGCAACATTACAGGGTGAAGCCACTTCATTATATATCCTGGCTGGTTGGACATGAAGGCAAAGGCAGCATTCTTTCTTTCCT
TAGGAAAAAATGCTGGGCTCTTGCACTGTTTGGTGGAAATGGTGAGACAGGATTTGAGCAAAATTCTACTTATTCAGTGTTCAGCATTTC
TATTACATTGACTGATGAGGGTTATGAACATTTTTATGAGGTTGCTTACACTGTCTTTCAGTATTTAAAAATGCTGCAGAAGCTAGGCCC
AGAAAAAAGAATTTTTGAAGAGATTCGGAAAATTGAGGATAATGAATTTCATTACCAAGAACAGACAGATCCAGTTGAGTATGTGGAAAA
CATGTGTGAGAACATGCAGCTGTACCCATTGCAGGACATTCTCACTGGAGATCAGCTTCTTTTTGAATACAAGCCAGAAGTCATTGGTGA
AGCCTTGAATCAGCTAGTTCCTCAAAAAGCAAATCTTGTTTTACTGTCTGGTGCTAATGAGGGAAAATGTGACCTCAAGGAGAAATGGTT
TGGAACTCAATATAGTATAGAAGATATTGAAAACTCTTGGGCTGAACTGTGGAATAGTAATTTCGAATTAAATCCAGATCTTCATCTTCC
AGCTGAAAACAAGTACATAGCCACGGACTTTACGTTGAAGGCTTTCGATTGCCCGGAAACAGAATACCCAGTTAAAATTGTGAATACTCC
ACAAGGTTGCCTGTGGTATAAGAAAGACAACAAATTCAAAATCCCCAAAGCATATATACGTTTCCATCTAATTTCACCGTTGATACAGAA
ATCTGCAGCAAATGTGGTCCTCTTTGATATCTTTGTCAATATCCTTACGCATAACCTTGCGGAACCAGCTTATGAAGCAGATGTGGCACA
GCTGGAGTATAAACTGGTAGCTGGAGAACATGGTTTAATTATTCGAGTGAAAGGATTTAACCACAAACTACCTCTACTGTTTCAGCTCAT
TATTGACTACTTAGCTGAGTTCAATTCCACACCAGCTGTCTTTACAATGATAACTGAGCAGTTGAAGAAGACCTACTTTAACATCCTCAT
CAAGCCCGAGACTTTGGCCAAAGATGTACGGCTTTTAATCTTGGAATATGCCCGTTGGTCTATGATTGACAAGTACCAGGCTTTGATGGA
CGGCCTTTCCCTTGAGTCTCTGCTGAGCTTCGTCAAAGAATTCAAATCCCAGCTCTTTGTGGAGGGCCTGGTACAAGGGAATGTCACAAG
CACAGAATCTATGGATTTCCTGAAATATGTTGTTGACAAACTAAACTTCAAGCCTCTGGAGCAGGAGATGCCTGTGCAGTTCCAGGTGGT
AGAGCTGCCCAGTGGCCACCATCTATGCAAAGTGAAAGCTCTGAACAAGGGTGATGCCAACTCTGAAGTCACTGTGTACTACCAGTCAGG
TACCAGGAGTCTAAGAGAATATACGCTTATGGAGCTGCTTGTGATGCAGTGGCAGAACGTGGAGCACGTTGGTGACCAGAGCCCCTACGT
CACCTCTGTCATTCTGCACATCAAGCAGAACGTCCCCATCATCCGTGACAACCTGGCTTCCACACGCAAGTACTTCACTCAGTTCTGCGT
TAAATTTGCAAACTCCTTCATTCCCAAATTCATCACCCACCTCTTCAAGTGCAAGCCAATTAGCATGGTGGGAGCAGAACAGCTGCTGCT
GGACACCCACTCGCTGAAGATGGTCCTGCTCGATCTCCCCTCCATCAGCTCGCAGGTGGTGAGGAAGGCACCCGCCAGCTACACCAAGAT
CGTTGTCAAAGGCATGACCCGGGCTGAGATGATCCTCAAGGTAGTGATGGCCCCTCATGAACCGTTGGTGGTGTTTGTTGACAACTACAT
CAAACTTCTCACAGACTGCAACACAGAAACCTTTCAGAAGATACTGGACATGAAGGGGCTGAAGAGGAGTGAGCAGAGCAGCATGCTGGA
ACTCCTGCGCCAGCGGCTCCCCGCACCGCCCTCGGGGGCAGAAAGCTCCGGCTCACTGTCCCTGACGGCGCCAACACCAGAGCAAGAGTC
GTCACGCATCCGCAAGCTCGAGAAACTCATTAAAAAGAGACTGTAGCAGCAGCAAGGGGCCCTTTGCTCCTGGCTGGAGACCCTCAGCGC
CCGTTCCCCAGAAGCCCCCAACCTCTCCTGTGCTCCCCGGCACTCTCACATCGTCGGTCTTCAAACTTCCTGGGACATGTGGGTTGTTAC
TGAGTCTCTCCCATGCCCTGTCTTACTTCCTGCCCTAATCGGAGACGCTGAGTAAGGGCTGGGCTCTAAGAGGGCGATTTAGGTGATCTC
TGGTTCGTGAAGCAGAGGCAGCAGTGGAGGATAGGTCCCTGAGCTGCCCTTGACTCATGTAGCCTCCCCATGGCAGTCACACCCTCTTGA
CACGTGGGCCCCACCCGTCCTTTTTTTTTTTTTTTTTTTTTTTTTTTGAGACAGAGTCTCGCTCTGTCACCCAGGCTGGAGTGCAGTGGC
GTGATCTCGGCTCACTGCAACCTCCGCCTCCCAGGTTCAAGCAATTCTCCTGCCTCAGCCTCCTGAGTATCGGATTACAGGCGTGAGCCA
CCGAGCCCAGCCCCTTCCTCCATTTCTTTACTCCCACCCTGCTCCTGGTTTCTAGGGAAGGGAAACCAGGAAGTTCACTTGGAAGACGTT
TCCTAGGTTTTCTCATCAGATGAAGCCATGGGAACGCCCAGGAAGTCCATACTCTCAAACCCCTTTCTGCCCACTCACCTTCAGGTCCAC
AGCACTTTCCAGCGTCATCTGAAATAGCAAAGGTGATGTGCAGCATCCCAGTGATGTGTTCCTGTGTTATGAGAAGGAGTCTGGGGTTCT
GGATGCCTCAGGAACAGAATATGGACCTTAAAGACCAGGCTGAGAGCCTGGCCTGGCACGCAGCCTGCCCGCCCCCCCCGCCCTTCCTGT
CCACCGCGGGCTCTCTGCAGCAGGGCTTGCCGAAGAGACTGCTCCCGACCTCTCATGTCATCCTGCATCCAGAGAATGGCAGCATATCAA
GCCGTTAACCCTGATTCACTCGGTTCCCTTGAAACCAGGCCTCAGTTAACCATGACCACAGCTACAGGCAAACCGCTGCTGTTGCTGCCT
GCTTTTGCTGAAGAATGATATCTTGCCAGGCACGGCGGCTCATGCCTGTAGTCGCAACACTTTGGGAGACCAAGGCAGGAGGATCACTTG
AGTCCAGGAGTTTGAGACCAGCCTGGGCAACATACAGATGTCTACAAAAATAAAAATTTGCAAGGTGTGGTGGCATGCACCTGTAGTCCC
AACTGCTAGGGAGGCTGAGGTGGGCAGATTGCTTGAGCTCAGGAGTTTGAGACCAGTCTGGGCAACCTGGCAAAACCAAAAATACAAAAA
ATTGGCTGGGTGTGGTGGCTCATGCCTGTAATCACAGCACTTTGGGAGGCTGAGGCAGGTGGATCACCTGAGGTCAGGAATTCGAGACCA
GCCTGCCCAACATGGCGAAACCCTGTCTCAACTAAAAATAAAAAAAATTAGCCGGGTGTCATGGCGAGTGCCTGTAATCCCAGCTACTGG
GGAGGCTGAGGCAGGAGAATCACTTAAACCCGGGAGGTGGAGGCTGCAGTGAGCCAAGATTTCACCACTGCACTCCAGCCTGGGTGACAG
AGCAAGACCCCTTCTCAAAAAGTTTTCAGGATAGAGGAAATTTCCTTAAAATCCATAAAACTTGTAACAGCCGTACAGTAGGAATAAGGT
TTGGAAATCTGCCTGGAAACCTGATTTCCTCATCCCCACCTTGTTTCCCAACATAACCACTGCTCTGTGCCCCTGCCCTCTCTGCCAGGC
TTTCTCCCCGATGCCGTCCAGCTCTGATCCTGAGTGTCATTTCTTCATCGGCTTCCAGGCTGTCCTTGCTAGCTGGTTTGACTCTCACGC
ATCAAGCGTCTCAAATTTGAGAATGCGGAGGAGAAAAGAAGTGTTGCGAGAAGGAGATGCGGCCTTCAGTTGAGGTCTATTAGGAAAAGA
TTCCAAATAAGACAAGGGCGGGGGGCGGCAGTCGGGAGAGCCCCCAGGAAGCCCTGTAGATGCCCCCACCCCAGCCCATGGAGTTGCTAT
GGTTAAGCAGCCTGAGCCGTACAGTTGAAAAGGGGCGGTGGGGCCCATCTCCAAATAGCACAGCCAGTTCAGCCGTCTGTCCTCAACCCA
GGAGAGCTGGGAAAGCCAGTGGACTCCTGCACCTGGTTCTTGTCACTCCTGGCGTTTGTGTACAGATCACCACTTCTCTTTTTGGTTCAT
TGTTGAGGAGTCGTTTTCCGGACGGCTCCATCACAGCATTGAGCTATCAAGCTGCTGTTTTCCACAGTTGGTGGTCACAGCCAGGGAAGT
TGCTGTCTTGATTTGTTACATTGTCAGTAATCCCCAAGGAACCAATGGATGTCAGTAGGAGTTTCTGTTAAATGTCTCCTTGATGGGGAC
TCAGTACTGTGTAGAGACGCTGTGTTTCTCTTCTGGGGGTGTGCATCAGAACCACTGGGGCCTTTTAAAATCTACAGATGCCGGCCGGGC
GCCGTGGCTCACGCCTGGAATCCCAGCACTTGGGGAGGCTGAGGCGGGCGGATCACAAGCGCAGGAAATTGAGACCATCCTTGCCAATAT
GGTGAAACCCCATCTCTACAAAAAATACAAAAATTACCGGGGTGTGGTGGCGTGCACACCTCCCAGCTACTTGGGAGGCTGAGGCAGGAG
AATCGCTTGAACCCGGGAGGCAAAGATTGCAGTGAGCCGAGATCACGCCACTGCACTCCAGCCTGGCGACAGAGTGAGACTCTATCTCAA
AACAAACAAAAAAACAGATGCCCGGAGATTTTGAGTCAGTAAGTTTGGATGGGGCCTGGCATACAGGTTTAAAAGTTCCATAGGTAGTTA
TAACGTTTACACCTTGTTAAGAACCACTGCAACAGAGAGATTTGCTTTATGGAAGGGCTCCTGCCACGCATTTTCATACATGTCTATTTT
TCTGACTCTAAGCTAAAAGTGCGCCGACACTACACTTGAGCTGGTGCCAACGTGGTGAAGATTCTCTACTGATAACAGCTTTCATTTTAA
ACTTGTGTTGGGTCAGGCGCGGTGGCTCACGCCTGTAATCCCAGCACTTTGGGAGGCCGAGGTGGGCGGATCACATGAGGTCACGAGTTT
GAGACCAGCCTGGCCAACATGGCAAAATCCCATCTCTACTAAAAATACAAAAAAAAAAAAAAAAAAAGCAGGCAGGTGGCGGGTGCCTGT
AATCCCAGCTACTTGGGAGGCTGAGGCAGGGGAATCAGTTGAATCCGGGAGGCGGAGGTTGCAGTGAGCCGAGGTCCCGCCACTGCACTC
CAGCCTGGGAGACAGAGTGAGACTCAGTTAAAAAAAAAAGACTTTTGGTGGTGGTGGGGACCATGCCCAGGATTGGGCTCTCTCCATACT
GATGAGGATTCTTCTTGTTTTGATGACCAACCCCCAAGCAGAAGCTTTATTTATTAACATCACTTCAAAAATAACGTATCAAAGGGGCAC
CCTAGGCCGGGTACTGTGGCATCACACCTGTAATGCCAGTGCTTTGAGAGGCTGAGGTGGGAAGATTGCTTGAGCCCAGGACTTCAAGAC
AAGCCTGGGCAACAGAGTGAGACCCCATCTCTATTAAAAAATAGGCCGGGCATGGTGGCTCACACTGGTAATCCCAGCACTTTGGGAGGC
CGAGGCAGGTGGATCATGTGAGGTCAGGAGTTCGAGACCAGCCTGGCCGACATGGTGAAACCCTGTCTTTACTAAAAATACAAAATTAGC
CAGGCGTGGTGGTGGGCGCCTGTAATCCCAGCTACTCAGGAGGCTGAAGCAGGAGGATCGCTTGAACCCAGGAGGCAGAGGCTGCAGTGA
GCCGAGATCATGCCATTGCACTCCTGCCTGGGTGACGGAGCAAGACTCTCTAAAAAATAATAAGGTAAAAGGAGTACCTGTGGATGAAAG
CAGCAGCTAACAGCTCTGTGATTCAGCTAGACCTAGATATTGTGCCCATTCCTTCCCCTCAGTCCATTTTCTGTAGCCCCTTTAAAAACC
AAAAAACAACTTTGAAGTCACTTTGGGTTTAAAATAAATAGTGGTAATTTGTATAATCAATAAAGAGTTCACTCTGCTCTTACTGAGGGG
ACTTGTCTGAAAGCTGGCTTAGCGGTGTCCAGGCCAGAGAACATCCTGTGTGGACTCTTAACAATGAAACAGGAGCCGCAATGGACAAGG
TGTTCTGATCTCCAAACCCAGCTCAGGGATTGAAGCTAACTACCGCCACTCCTTCCTCTCTCGAAGAACAAAGAGCCAGTACCCAGGGCT
CTGCCCACCCCCGAGAAGGGGTGCCTGATTTCTTATGTCTAGGGTGGCTCCTCTGTGCAGATCAGACAGGACTGAGAGCAGACAAGCTGA
GACCAGCATGACCAGTACAGGGCACGCAGAGCGTGGGGGCAGGTCCGAGGCTGCTGCTCGATGCAGGGTATGACACCAACCCTTCCTGAA
TTGCCATCGGATGAGGAGACCTGGTTCCCTGTTGAAAGAATGCCAGGGGAAATGCTGCATGTGCACAGCTGGAAATGGGGTTCCTTCTCT
AGGAAGAGCACTCGGAATAACCTGCTGGAAATGGGGTTCCTTCCCTAGGAAGAGCACTCAGAATAACCTGCTGGAAATGGGATTCCTTGG
CTAGGAAGAGCACTCAGAATAACCTGCTGGAAATGGGATTCCTTGGCTAGGAAGAGCACTCAGAATAACCTGCTGGAAATGGGATTCCTT
ACCTAGGAAGAGCACTCGGAATAACCTGCTGGAAATGGGATTCCTTACCTAGGAAGAGCACTCGGAATAACCTGCTGGAAATGGGGTTCC
TTCCCTAGGAAGAGCACTCGGAATAACCTGCTGGAAATGGGGTTCCTTCCCTAGGAAGAGCACTCGGAATAACCTGCTGGAAATGGGGTT
CCTTCGCTAGGAAGAGCACTCGGAATAACCTGCTGGAAATGGGATTCCTTCGCTAGGAAGAGCACTCGGAATAACCTGCTGGAAATGGGA
TTCCTTCGCTAGGAAGAGCACTCGGAATAACCTGCTGGAAATGAGATTCCTTCCCTAGGAAGAGCACTCGGAATAACCTGCTGGAAATGG
GATTCCTTCGCTAGGAAGAGCACTCGGAATAACCTGCTGGAAATGAGATTCCTTCGCTAGGAAGAGCACTCGGAATAACCTGCTGGAAAT
GGGATTCCTTCGCTAGGAAGAGCACTCGGAATAACCTGCTGGAAATGAGATTCCTTCGCTAGGAAGAGCACTCGGAATAACCTGCTGGAA
ATGGGATTCCTTCGCTAGGAAGAGCACTCGGAATAACCTGCTGGAAATGGGATTCCTTCGCTAGGAAGAGCACTCGGAATAACCTGCTGG
AAATGGGATTCCTTCCCTAGGAAGAGCACTCGGAATAACCTGCTGGAAATGAGATTCCTTCCCTAGGAAGAGCACTCGGAATAACCTGCT
GGAAATGGGATTCCTTCGCTAGGAAGAGCACTCGGAATAACCTGCTGGAAATGGGATTCCTTCGCTAGGAAGAGCACTCAGAACAACCTG
CCTGCTTGAGGGTGACAGCAAGTGTCTCACACTTCTCGTCTACTCCAAGTCAGATTCCTAAAAATAAAATAGAGCTCCAATGGGCAATTT
AAGCAAAAGCCTTAGAAACATGGACACCTGAAATGCTGGCCTACATGAAGGGTACGATGACATTTTATATATTAAATAAAAATTCCCAGT
CCTGTTTTAGTATTCATCAGAATAGCCTCTTGGACCCTCGAAGTTCTACACCTTTGGGAGATATAAATTTCCTTAAAATAAAGGGATTGC
TTCTTTGTGTAAATAGCTTTCATTTTCTCCATCTGGAAGTGATTTCTGCCTGCATGTTGGAGCACAAAATACTGCAGTTAATTAAAGCAT
TACTGGATGTCATTTGCTAGAATGTATTTCCTTACTGCTGACAGAAAACAGAACAGACTCTAGGAAAGAAGTAGCAAGTCCGTGACCCTG
GCCGCTCCTGGTGGCTGCCCTTCTCCCTTCCCTGACAGTCTAAGGAAGCAACGCGTGGGAGCAGAATGTGGCCGACTGAGCCCAGTCCTG
ACCTGCCCAGTTGCAGTGGAGCCTGTCTGTAATGTTGTGTAAAGTGTTTTGCTTCTGACTTGGAACCCTACTTGCCCTGTGAATTTCTAT
CCTGTGAACCTTCCCTTCTCTGTCCTTACCGTTCCCATCACAGCCTGCTCTTCCAGTGACGGCCAAGTGATTTCTCTCCTGCACGCATGA
GTCCATCCTGTTTCCTTAGTAGCTGGATGGACGTTTTGCCATGAAAACTCTTTGGGAAGTCTTGTGTCCTTTAGTGATTTCTCTCCTGCA
CGCATGAGTCCATCCTGTTTCCTTAGTAGCTGGTTGGACGTTTTTGCCATGAAAACTCTTCGGGAAGTCCTGTGTCCTTTCAACAGGGGA
AAACTGGCTGCGGCCCTTCCATTAGGCTCCAGGATCATTACCTCGTTTCCATTCTTTCTTTTCAACAGCTCCCCACTTTACTAGGGAAGC
CAAGGGATCAACCTAATGAGAAAAGAACCTTCCCTGTAGCCCACCTGGAAGGGCATTGCCTGCCAGCTCCTTCCTTCTCACCTATGTGAA
CAGGAGGGAAGATGCCGGCGATCCATGGATCTGTGGGACATGAAGGACGTGTCCATCAGAAATGAAAGCAGCCTGGGATTGGAAGCATCC
ACAGAAGACTTGATCTGCAGGTCTTGATTTGGACCTGGCACTTTGACACCAGGCGAGTCACTGATCCCCTGAGCATCCATTTTCAATATT
GGTGAGAGGGGATTATAATGAATATTGGCTGTGAAGGTCACACAAGACCGGGCTATATGCACTTGCTCTGCCATAAGGCAGTGTGAAGTG
TGTTCGTGATCACTTGTGGGCGGGAGCCTGTGGCTGTCTTGCCTGGACTGGCTTTTTTAAACATGGATGAGTGGTGACAAATCCTGCGGC
CGTGTGCAGGCTACATCCGCAGCGAGCTCCGCATATCTGGTCTTTGCCTTTTTAGGTCATGACTGTAATATCAAGCTTACACGAGAGTTT
TAAAAGACTGAGCAGTATCCCCTTCCCCTGGCAGCTGCTGCTTCCGTAGCATTTAGGGATAAACCTGCAGACACTGAGAAGAGAGCTTCC
TCCCTCCTGGGGCTGGTGGCGAGGCTGCCTGTTGTGGAAAATAGGGCATGTCTCCTGTGAATGCGAATTGCGAGGGTTGCCAAAGCCTCC
CTTCCAAGAAACTTGCTTAGGTGTCTGGTGTCCACAGACCAGACTCTTCTCCCGACAGGGACAAAAATTCTTGCCTGCCTTTCTTTTTCT
TTTTTTTCCTTTTACTTATTCTTGCCTTTTTTCTTCTTCTTCTTCTTTAGGTATGATGCCCCCCAAAAAACTAAGCAAGATTAACTTGGG
ACAGGCAGTTCTAACTGGGAAGCCTGAGCTCACAGGCTGTTTGGATTACTTTCCAATTGTGTTTCAAAGATGTTTAGACTTTTCCCAAGG
CCAGCTGAATCCTTATAATCAGCCCAAAAGTTCCTTTCTGTTTCTGTCTGTCCCCTTTGAGGGTGTTGACTCAGAGAACCTGGGGCAATA
TGAGATGTTAAAATAAAAATAGCGTCCAACGTCCCGCCTCCTGGGAATGCTGCTCACTTCATCCGAGGGTTCTGGGAGCTTCTGCTCAGT
CATCAAATGGAATTTGCACAATTGTCTTGCCTCCTGTTTTGGGTAATTTTTCAACAAGTGAGAAATTAAGAACAGCTTCTCAACAAACTT
CCCTCTACTTCCAGGGCCAAGAAAAGTATTTGCAGTGTGGGCTGCAGCTTTCAGGGGTCTCAGGTGAAATGGTGGCAAGAAACCCCAGCT
CCCTTCATGTGTTTGCCTTGCGCTGATGGAAAAGGAAGGCACTTCTCAGCTGCCAGAGACCACATTCCACAGGGTTCTTCACAAAATCAA
GCACTGCAGTGGACCAACTGGAGCAGCCACTGGAGGGCTTTAGAAGGCAAATGGAATACATATCAAATGCTATATAAAGAAAACATCTGT
TTACACAGAGTCCCCCACAGCCTCATACCTACACCCAATATCAAATGCTGTATAAAGAAACATCAGTTTACACACAGAGCCCCCCACAAC
CTCATACCCACACCGAATATCAAATGCTATACAAAGAAACATCAGTTTACACACAGAGTCCCCCACAGCCTCATACCCATGCCTGTCACA
TCTTTGCACAGCCCTAAAGGATCCAGAGCTTTGGATCAGCAGCTGGCTAGCTCGGAGGCCAGAGGAGGGTGCTGAGGGGAGTGGAGGTCA
GTTGGGGTAGCCCTGGGCCCTGGCTGCACAGTCCAGCTGCTGTGTGGCCTGCATGTGGTATCTTAGGTCATGAGAGGGCCTGGGCAATTC
AGTGCTATCTGTACATGTTGGTGGGGTGGGAAGGAAAAGGTAACTGTGTATTTACTGTGTCCTGGATACATTATCTCATCGGATGAAATT
CCTGCTAAGTTAAGCTCCGTTTAGTGGACGGGACTTGGAGGCTCAAAGAGGGTAAGTGACAGGCCCAAGGATATGTGCCTAGTGAGGGGT
GAGCCAGGATTCGATGTGTGACTAGTAAGGGGTCAGCCAGGATTCAATATGTGACTAGTAAGGGGTCAGCCAGGATTTCATATGGGACTA
GTAAGGGGTCGGCCAGGATTTGATACGTGACTAGCAAGGGGACAAGCCAGGATTTGATATGTGACTAGTGAGGGGCGAGCCAGGATTCGA
TATGTGACTAGTAAGGGGTCAGCCAAGATTTGATATGTGACTAGTGAGGGGCGAGACAGGATTTGATATGTGACTAGTGAGGGGCGAGCC
AGGATTTGATATGTGACTGGTGAGGGGCGAGCCAGGATTTGATATGTGACTGGTGAGGGGCGAGCCAGGATTTGATATGTGACTGGTGAG
GGGCGAGCCAGGATTTGATATGTGACTGGTGAGGGGCGAGCCAGGATTTGATATGTGACTGGTGAGGGGCGAGCCAGGATTTGATATGTG
ACTGGTGAGGGGCGAGCCAGGATTTGATATGTGACTGGTGAGGGGCGAGCCAGGATTTGATATGTGACTGGTGAGGGGCGAGCCAGGATT
TGATATGTGACTGGTGAGGGGCGAGCCAGGATTTGATATGTGACTGGTGAGGGGCGAGCCAGGATTTGATATGTGACTGGTGAGGGGCGA
GCCAGGATTTGATATGTGACTGGTGAGGGGTGGAGCCAGTCAGGATTTGATATGTGGTTAGTGAGGGGTTAGCCAGTCAGGATTTGATAT
GTGGCTAGTGAGGGGCGAGCCAGGATTTGATATGTGACTAGTAAGGGGGTGAGCCAGGATTCAATACGTGACAAGTGAGGGGTGAGCCAG
GATTCAATACGTGACCAGTGAGGGGCGAGCCAGGATTCGATACGTGACCAGTGAGGGGCGAGCCAGGATGCGATACGTGACCAGTGAGGG
GCGAGCCAGGATTCCATACGTGACTAGTGAGGGGTGAGCCAGGATTCGATATGTGAGTAGTGAGGAGTGAGCCAGGATTTGATATGTGGC
TACTGAGGGGCGAGCCAGGATTTGATATGTGACTAGTAAGGGGTCAGCCAGGATTTGATACGTGACTAGTCAGGGGGTCAGCCAGGATTC
GATACGTGACTAGTAAGGGGTCAGCCAGGATTTGATATGTGACTAGTGAGGGGTGAGCCAGGATTTGACATGTGACTAGTGAGGGGTGAG
CCAGGATTCAATATGTGACTAGTGAGGGGTGAGCCAGGATTCGATATGTACCTAGTGAGGGGTCAGCCAGGATTTGATATGTGGCTAGTA
AGGGGTGAGCCAGCCAGGATTTGATATGTGACTAGTGACGAGTGAGCCAGGATTTGATATGTGACTAGTAAGGGGGTGAGGCAGGATTTG
ATATGTGACTAGTAAGGGGGTGAGGCAGGATTTGATATGTGACTGGTGAGGGGTGAGACAGGATTTGATATGTGACTAGTGAGGGGTGAG
CCAGGATTTGCTATGTGACTAGTAAGGGGGCGAGCCAGGATTTGGCTCCAGCCTTCATTCCAACATCCATGCCTTTTGTACTTCACCAGC
AGTTTTCAAATTTATGGGACAAAATTTTACATTGGATTCCCTCTATACAAAATAGATAAAAGTATTTTATGAATACATTTTATGAGTTCA
AATATTTTTCAGAAGAAATCAGTAAAAGCATTGAAAACTATTCCAGCAAATAGGAAGCACTTTAAACCAAGGTTATGGATGAAAATGTGT
GTGTATCAACCCCAGTTTACTTCTGGGTTGCACAGAATAGAGAAATCTTGATTTAATCCAGCTAAGAATTTTCAAATAGTATCCATTTTG

>60237_60237_3_NRD1-VPS53_NRD1_chr1_52258049_ENST00000352171_VPS53_chr17_440416_ENST00000437048_length(amino acids)=1151AA_BP=941
MLRRVTVAAVCATRRKLCEAGRELAALWGIETRGRCEDSAAARPFPILAMPGRNKAKSTCSCPDLQPNGQDLGENSRVARLGADESEEEG
RRGSLSNAGDPEIVKSPSDPKQYRYIKLQNGLQALLISDLSNMEGKTGNTTDDEEEEEVEEEEEDDDEDSGAEIEDDDEEGFDDEDEFDD
EHDDDLDTEDNELEELEERAEARKKTTEKQSAAALCVGVGSFADPDDLPGLAHFLEHMVFMGSLKYPDENGFDAFLKKHGGSDNASTDCE
RTVFQFDVQRKYFKEALDRWAQFFIHPLMIRDAIDREVEAVDSEYQLARPSDANRKEMLFGSLARPGHPMGKFFWGNAETLKHEPRKNNI
DTHARLREFWMRYYSSHYMTLVVQSKETLDTLEKWVTEIFSQIPNNGLPRPNFGHLTDPFDTPAFNKLYRVVPIRKIHALTITWALPPQQ
QHYRVKPLHYISWLVGHEGKGSILSFLRKKCWALALFGGNGETGFEQNSTYSVFSISITLTDEGYEHFYEVAYTVFQYLKMLQKLGPEKR
IFEEIRKIEDNEFHYQEQTDPVEYVENMCENMQLYPLQDILTGDQLLFEYKPEVIGEALNQLVPQKANLVLLSGANEGKCDLKEKWFGTQ
YSIEDIENSWAELWNSNFELNPDLHLPAENKYIATDFTLKAFDCPETEYPVKIVNTPQGCLWYKKDNKFKIPKAYIRFHLISPLIQKSAA
NVVLFDIFVNILTHNLAEPAYEADVAQLEYKLVAGEHGLIIRVKGFNHKLPLLFQLIIDYLAEFNSTPAVFTMITEQLKKTYFNILIKPE
TLAKDVRLLILEYARWSMIDKYQALMDGLSLESLLSFVKEFKSQLFVEGLVQGNVTSTESMDFLKYVVDKLNFKPLEQEMPVQFQVVELP
SGHHLCKVKALNKGDANSEVTVYYQSGTRSLREYTLMELLVMQWQNVEHVGDQSPYVTSVILHIKQNVPIIRDNLASTRKYFTQFCVKFA
NSFIPKFITHLFKCKPISMVGAEQLLLDTHSLKMVLLDLPSISSQVVRKAPASYTKIVVKGMTRAEMILKVVMAPHEPLVVFVDNYIKLL

--------------------------------------------------------------
>60237_60237_4_NRD1-VPS53_NRD1_chr1_52258049_ENST00000354831_VPS53_chr17_440416_ENST00000437048_length(transcript)=14310nt_BP=3217nt
AGTAGCGTCATCGGCGGCCGGGAGGGCGGAGGGACGAGGGAAGTCGGCGAGAGGGAGACTGGGTTGGGGGAGGGGTTCAGGCCTGTTCCC
CGCGGCTGCGGCAGCACCAGGGCCGGCCGCCACCGCCTCTAGAACGCGGAGGAGGTGGGTCCTGGGAAGCGGGATGTCCATCGCTCCAGC
TTGGTGGTGAATGCTGAGGAGAGTCACTGTTGCTGCAGTCTGTGCCACCCGGAGGAAGTTGTGTGAGGCCGGGCGGGAGCTCGCGGCGCT
CTGGGGAATCGAAACGCGGGGTCGGTGCGAAGACTCTGCTGCTGCCAGACCCTTTCCTATTCTGGCCATGCCTGGAAGGAACAAGGCGAA
GTCTACCTGCAGCTGCCCTGACCTGCAGCCCAATGGACAGGATCTGGGCGAGAACAGCCGGGTTGCCCGTCTAGGAGCGGATGAATCTGA
GGAAGAGGGACGGAGGGGGTCTCTCAGTAATGCTGGGGACCCTGAGATCGTCAAGTCTCCCAGCGACCCCAAGCAATACCGATACATCAA
ATTACAGAATGGCTTGCAGGCACTTCTGATTTCAGACCTAAGTAATATGGAAGGTAAAACAGGAAATACAACAGATGATGAAGAAGAAGA
GGAGGTGGAGGAAGAAGAAGAAGATGATGATGAAGATTCTGGAGCTGAAATAGAAGATGACGATGAAGAGGGTTTTGATGATGAAGATGA
GTTTGATGATGAACATGATGATGATCTTGATACTGAGGATAATGAATTGGAAGAATTAGAAGAGAGAGCAGAAGCTAGAAAAAAAACTAC
TGAAAAACAGCAATTGCAGAGCCTGTTTTTGCTGTGGTCAAAGCTGACTGATAGACTGTGGTTTAAGTCAACTTATTCAAAAATGTCTTC
AACCCTGCTGGTCGAGACAAGAAATCTTTATGGGGTAGTTGGAGCTGAAAGCAGGTCTGCACCTGTTCAGCATTTGGCAGGATGGCAAGC
GGAGGAGCAGCAGGGTGAAACTGACACAGTTCTGTCTGCAGCGGCTCTTTGTGTTGGAGTTGGGAGTTTCGCTGATCCAGATGACCTGCC
GGGGCTGGCACACTTTTTGGAGCACATGGTATTCATGGGTAGTTTGAAATATCCAGATGAGAATGGATTTGATGCCTTCCTGAAGAAGCA
TGGGGGTAGTGATAATGCCTCAACTGATTGTGAACGCACTGTCTTTCAGTTTGATGTCCAGAGGAAGTACTTCAAGGAAGCTCTTGATAG
ATGGGCGCAGTTCTTCATCCACCCACTAATGATCAGAGATGCAATTGACCGTGAAGTTGAAGCTGTTGATAGTGAATATCAACTTGCAAG
GCCTTCTGATGCAAACAGAAAGGAAATGTTGTTTGGAAGCCTTGCTAGACCTGGACATCCTATGGGAAAATTTTTTTGGGGAAATGCTGA
GACGCTCAAGCATGAGCCAAGAAAGAATAATATTGATACACATGCTAGATTGAGAGAATTCTGGATGCGTTACTACTCTTCTCATTACAT
GACTTTAGTGGTTCAATCCAAAGAAACACTGGATACTTTGGAAAAGTGGGTGACTGAAATCTTCTCTCAGATACCAAACAATGGGTTACC
CAGACCAAACTTTGGCCATTTAACGGATCCATTTGACACACCAGCATTTAACAAACTTTATAGAGTTGTTCCAATCAGAAAAATTCATGC
TCTGACCATCACATGGGCACTTCCTCCTCAACAGCAACATTACAGGGTGAAGCCACTTCATTATATATCCTGGCTGGTTGGACATGAAGG
CAAAGGCAGCATTCTTTCTTTCCTTAGGAAAAAATGCTGGGCTCTTGCACTGTTTGGTGGAAATGGTGAGACAGGATTTGAGCAAAATTC
TACTTATTCAGTGTTCAGCATTTCTATTACATTGACTGATGAGGGTTATGAACATTTTTATGAGGTTGCTTACACTGTCTTTCAGTATTT
AAAAATGCTGCAGAAGCTAGGCCCAGAAAAAAGAATTTTTGAAGAGATTCGGAAAATTGAGGATAATGAATTTCATTACCAAGAACAGAC
AGATCCAGTTGAGTATGTGGAAAACATGTGTGAGAACATGCAGCTGTACCCATTGCAGGACATTCTCACTGGAGATCAGCTTCTTTTTGA
ATACAAGCCAGAAGTCATTGGTGAAGCCTTGAATCAGCTAGTTCCTCAAAAAGCAAATCTTGTTTTACTGTCTGGTGCTAATGAGGGAAA
ATGTGACCTCAAGGAGAAATGGTTTGGAACTCAATATAGTATAGAAGATATTGAAAACTCTTGGGCTGAACTGTGGAATAGTAATTTCGA
ATTAAATCCAGATCTTCATCTTCCAGCTGAAAACAAGTACATAGCCACGGACTTTACGTTGAAGGCTTTCGATTGCCCGGAAACAGAATA
CCCAGTTAAAATTGTGAATACTCCACAAGGTTGCCTGTGGTATAAGAAAGACAACAAATTCAAAATCCCCAAAGCATATATACGTTTCCA
TCTAATTTCACCGTTGATACAGAAATCTGCAGCAAATGTGGTCCTCTTTGATATCTTTGTCAATATCCTTACGCATAACCTTGCGGAACC
AGCTTATGAAGCAGATGTGGCACAGCTGGAGTATAAACTGGTAGCTGGAGAACATGGTTTAATTATTCGAGTGAAAGGATTTAACCACAA
ACTACCTCTACTGTTTCAGCTCATTATTGACTACTTAGCTGAGTTCAATTCCACACCAGCTGTCTTTACAATGATAACTGAGCAGTTGAA
GAAGACCTACTTTAACATCCTCATCAAGCCCGAGACTTTGGCCAAAGATGTACGGCTTTTAATCTTGGAATATGCCCGTTGGTCTATGAT
TGACAAGTACCAGGCTTTGATGGACGGCCTTTCCCTTGAGTCTCTGCTGAGCTTCGTCAAAGAATTCAAATCCCAGCTCTTTGTGGAGGG
CCTGGTACAAGGGAATGTCACAAGCACAGAATCTATGGATTTCCTGAAATATGTTGTTGACAAACTAAACTTCAAGCCTCTGGAGCAGGA
GATGCCTGTGCAGTTCCAGGTGGTAGAGCTGCCCAGTGGCCACCATCTATGCAAAGTGAAAGCTCTGAACAAGGGTGATGCCAACTCTGA
AGTCACTGTGTACTACCAGTCAGGTACCAGGAGTCTAAGAGAATATACGCTTATGGAGCTGCTTGTGATGCAGTGGCAGAACGTGGAGCA
CGTTGGTGACCAGAGCCCCTACGTCACCTCTGTCATTCTGCACATCAAGCAGAACGTCCCCATCATCCGTGACAACCTGGCTTCCACACG
CAAGTACTTCACTCAGTTCTGCGTTAAATTTGCAAACTCCTTCATTCCCAAATTCATCACCCACCTCTTCAAGTGCAAGCCAATTAGCAT
GGTGGGAGCAGAACAGCTGCTGCTGGACACCCACTCGCTGAAGATGGTCCTGCTCGATCTCCCCTCCATCAGCTCGCAGGTGGTGAGGAA
GGCACCCGCCAGCTACACCAAGATCGTTGTCAAAGGCATGACCCGGGCTGAGATGATCCTCAAGGTAGTGATGGCCCCTCATGAACCGTT
GGTGGTGTTTGTTGACAACTACATCAAACTTCTCACAGACTGCAACACAGAAACCTTTCAGAAGATACTGGACATGAAGGGGCTGAAGAG
GAGTGAGCAGAGCAGCATGCTGGAACTCCTGCGCCAGCGGCTCCCCGCACCGCCCTCGGGGGCAGAAAGCTCCGGCTCACTGTCCCTGAC
GGCGCCAACACCAGAGCAAGAGTCGTCACGCATCCGCAAGCTCGAGAAACTCATTAAAAAGAGACTGTAGCAGCAGCAAGGGGCCCTTTG
CTCCTGGCTGGAGACCCTCAGCGCCCGTTCCCCAGAAGCCCCCAACCTCTCCTGTGCTCCCCGGCACTCTCACATCGTCGGTCTTCAAAC
TTCCTGGGACATGTGGGTTGTTACTGAGTCTCTCCCATGCCCTGTCTTACTTCCTGCCCTAATCGGAGACGCTGAGTAAGGGCTGGGCTC
TAAGAGGGCGATTTAGGTGATCTCTGGTTCGTGAAGCAGAGGCAGCAGTGGAGGATAGGTCCCTGAGCTGCCCTTGACTCATGTAGCCTC
CCCATGGCAGTCACACCCTCTTGACACGTGGGCCCCACCCGTCCTTTTTTTTTTTTTTTTTTTTTTTTTTTGAGACAGAGTCTCGCTCTG
TCACCCAGGCTGGAGTGCAGTGGCGTGATCTCGGCTCACTGCAACCTCCGCCTCCCAGGTTCAAGCAATTCTCCTGCCTCAGCCTCCTGA
GTATCGGATTACAGGCGTGAGCCACCGAGCCCAGCCCCTTCCTCCATTTCTTTACTCCCACCCTGCTCCTGGTTTCTAGGGAAGGGAAAC
CAGGAAGTTCACTTGGAAGACGTTTCCTAGGTTTTCTCATCAGATGAAGCCATGGGAACGCCCAGGAAGTCCATACTCTCAAACCCCTTT
CTGCCCACTCACCTTCAGGTCCACAGCACTTTCCAGCGTCATCTGAAATAGCAAAGGTGATGTGCAGCATCCCAGTGATGTGTTCCTGTG
TTATGAGAAGGAGTCTGGGGTTCTGGATGCCTCAGGAACAGAATATGGACCTTAAAGACCAGGCTGAGAGCCTGGCCTGGCACGCAGCCT
GCCCGCCCCCCCCGCCCTTCCTGTCCACCGCGGGCTCTCTGCAGCAGGGCTTGCCGAAGAGACTGCTCCCGACCTCTCATGTCATCCTGC
ATCCAGAGAATGGCAGCATATCAAGCCGTTAACCCTGATTCACTCGGTTCCCTTGAAACCAGGCCTCAGTTAACCATGACCACAGCTACA
GGCAAACCGCTGCTGTTGCTGCCTGCTTTTGCTGAAGAATGATATCTTGCCAGGCACGGCGGCTCATGCCTGTAGTCGCAACACTTTGGG
AGACCAAGGCAGGAGGATCACTTGAGTCCAGGAGTTTGAGACCAGCCTGGGCAACATACAGATGTCTACAAAAATAAAAATTTGCAAGGT
GTGGTGGCATGCACCTGTAGTCCCAACTGCTAGGGAGGCTGAGGTGGGCAGATTGCTTGAGCTCAGGAGTTTGAGACCAGTCTGGGCAAC
CTGGCAAAACCAAAAATACAAAAAATTGGCTGGGTGTGGTGGCTCATGCCTGTAATCACAGCACTTTGGGAGGCTGAGGCAGGTGGATCA
CCTGAGGTCAGGAATTCGAGACCAGCCTGCCCAACATGGCGAAACCCTGTCTCAACTAAAAATAAAAAAAATTAGCCGGGTGTCATGGCG
AGTGCCTGTAATCCCAGCTACTGGGGAGGCTGAGGCAGGAGAATCACTTAAACCCGGGAGGTGGAGGCTGCAGTGAGCCAAGATTTCACC
ACTGCACTCCAGCCTGGGTGACAGAGCAAGACCCCTTCTCAAAAAGTTTTCAGGATAGAGGAAATTTCCTTAAAATCCATAAAACTTGTA
ACAGCCGTACAGTAGGAATAAGGTTTGGAAATCTGCCTGGAAACCTGATTTCCTCATCCCCACCTTGTTTCCCAACATAACCACTGCTCT
GTGCCCCTGCCCTCTCTGCCAGGCTTTCTCCCCGATGCCGTCCAGCTCTGATCCTGAGTGTCATTTCTTCATCGGCTTCCAGGCTGTCCT
TGCTAGCTGGTTTGACTCTCACGCATCAAGCGTCTCAAATTTGAGAATGCGGAGGAGAAAAGAAGTGTTGCGAGAAGGAGATGCGGCCTT
CAGTTGAGGTCTATTAGGAAAAGATTCCAAATAAGACAAGGGCGGGGGGCGGCAGTCGGGAGAGCCCCCAGGAAGCCCTGTAGATGCCCC
CACCCCAGCCCATGGAGTTGCTATGGTTAAGCAGCCTGAGCCGTACAGTTGAAAAGGGGCGGTGGGGCCCATCTCCAAATAGCACAGCCA
GTTCAGCCGTCTGTCCTCAACCCAGGAGAGCTGGGAAAGCCAGTGGACTCCTGCACCTGGTTCTTGTCACTCCTGGCGTTTGTGTACAGA
TCACCACTTCTCTTTTTGGTTCATTGTTGAGGAGTCGTTTTCCGGACGGCTCCATCACAGCATTGAGCTATCAAGCTGCTGTTTTCCACA
GTTGGTGGTCACAGCCAGGGAAGTTGCTGTCTTGATTTGTTACATTGTCAGTAATCCCCAAGGAACCAATGGATGTCAGTAGGAGTTTCT
GTTAAATGTCTCCTTGATGGGGACTCAGTACTGTGTAGAGACGCTGTGTTTCTCTTCTGGGGGTGTGCATCAGAACCACTGGGGCCTTTT
AAAATCTACAGATGCCGGCCGGGCGCCGTGGCTCACGCCTGGAATCCCAGCACTTGGGGAGGCTGAGGCGGGCGGATCACAAGCGCAGGA
AATTGAGACCATCCTTGCCAATATGGTGAAACCCCATCTCTACAAAAAATACAAAAATTACCGGGGTGTGGTGGCGTGCACACCTCCCAG
CTACTTGGGAGGCTGAGGCAGGAGAATCGCTTGAACCCGGGAGGCAAAGATTGCAGTGAGCCGAGATCACGCCACTGCACTCCAGCCTGG
CGACAGAGTGAGACTCTATCTCAAAACAAACAAAAAAACAGATGCCCGGAGATTTTGAGTCAGTAAGTTTGGATGGGGCCTGGCATACAG
GTTTAAAAGTTCCATAGGTAGTTATAACGTTTACACCTTGTTAAGAACCACTGCAACAGAGAGATTTGCTTTATGGAAGGGCTCCTGCCA
CGCATTTTCATACATGTCTATTTTTCTGACTCTAAGCTAAAAGTGCGCCGACACTACACTTGAGCTGGTGCCAACGTGGTGAAGATTCTC
TACTGATAACAGCTTTCATTTTAAACTTGTGTTGGGTCAGGCGCGGTGGCTCACGCCTGTAATCCCAGCACTTTGGGAGGCCGAGGTGGG
CGGATCACATGAGGTCACGAGTTTGAGACCAGCCTGGCCAACATGGCAAAATCCCATCTCTACTAAAAATACAAAAAAAAAAAAAAAAAA
AGCAGGCAGGTGGCGGGTGCCTGTAATCCCAGCTACTTGGGAGGCTGAGGCAGGGGAATCAGTTGAATCCGGGAGGCGGAGGTTGCAGTG
AGCCGAGGTCCCGCCACTGCACTCCAGCCTGGGAGACAGAGTGAGACTCAGTTAAAAAAAAAAGACTTTTGGTGGTGGTGGGGACCATGC
CCAGGATTGGGCTCTCTCCATACTGATGAGGATTCTTCTTGTTTTGATGACCAACCCCCAAGCAGAAGCTTTATTTATTAACATCACTTC
AAAAATAACGTATCAAAGGGGCACCCTAGGCCGGGTACTGTGGCATCACACCTGTAATGCCAGTGCTTTGAGAGGCTGAGGTGGGAAGAT
TGCTTGAGCCCAGGACTTCAAGACAAGCCTGGGCAACAGAGTGAGACCCCATCTCTATTAAAAAATAGGCCGGGCATGGTGGCTCACACT
GGTAATCCCAGCACTTTGGGAGGCCGAGGCAGGTGGATCATGTGAGGTCAGGAGTTCGAGACCAGCCTGGCCGACATGGTGAAACCCTGT
CTTTACTAAAAATACAAAATTAGCCAGGCGTGGTGGTGGGCGCCTGTAATCCCAGCTACTCAGGAGGCTGAAGCAGGAGGATCGCTTGAA
CCCAGGAGGCAGAGGCTGCAGTGAGCCGAGATCATGCCATTGCACTCCTGCCTGGGTGACGGAGCAAGACTCTCTAAAAAATAATAAGGT
AAAAGGAGTACCTGTGGATGAAAGCAGCAGCTAACAGCTCTGTGATTCAGCTAGACCTAGATATTGTGCCCATTCCTTCCCCTCAGTCCA
TTTTCTGTAGCCCCTTTAAAAACCAAAAAACAACTTTGAAGTCACTTTGGGTTTAAAATAAATAGTGGTAATTTGTATAATCAATAAAGA
GTTCACTCTGCTCTTACTGAGGGGACTTGTCTGAAAGCTGGCTTAGCGGTGTCCAGGCCAGAGAACATCCTGTGTGGACTCTTAACAATG
AAACAGGAGCCGCAATGGACAAGGTGTTCTGATCTCCAAACCCAGCTCAGGGATTGAAGCTAACTACCGCCACTCCTTCCTCTCTCGAAG
AACAAAGAGCCAGTACCCAGGGCTCTGCCCACCCCCGAGAAGGGGTGCCTGATTTCTTATGTCTAGGGTGGCTCCTCTGTGCAGATCAGA
CAGGACTGAGAGCAGACAAGCTGAGACCAGCATGACCAGTACAGGGCACGCAGAGCGTGGGGGCAGGTCCGAGGCTGCTGCTCGATGCAG
GGTATGACACCAACCCTTCCTGAATTGCCATCGGATGAGGAGACCTGGTTCCCTGTTGAAAGAATGCCAGGGGAAATGCTGCATGTGCAC
AGCTGGAAATGGGGTTCCTTCTCTAGGAAGAGCACTCGGAATAACCTGCTGGAAATGGGGTTCCTTCCCTAGGAAGAGCACTCAGAATAA
CCTGCTGGAAATGGGATTCCTTGGCTAGGAAGAGCACTCAGAATAACCTGCTGGAAATGGGATTCCTTGGCTAGGAAGAGCACTCAGAAT
AACCTGCTGGAAATGGGATTCCTTACCTAGGAAGAGCACTCGGAATAACCTGCTGGAAATGGGATTCCTTACCTAGGAAGAGCACTCGGA
ATAACCTGCTGGAAATGGGGTTCCTTCCCTAGGAAGAGCACTCGGAATAACCTGCTGGAAATGGGGTTCCTTCCCTAGGAAGAGCACTCG
GAATAACCTGCTGGAAATGGGGTTCCTTCGCTAGGAAGAGCACTCGGAATAACCTGCTGGAAATGGGATTCCTTCGCTAGGAAGAGCACT
CGGAATAACCTGCTGGAAATGGGATTCCTTCGCTAGGAAGAGCACTCGGAATAACCTGCTGGAAATGAGATTCCTTCCCTAGGAAGAGCA
CTCGGAATAACCTGCTGGAAATGGGATTCCTTCGCTAGGAAGAGCACTCGGAATAACCTGCTGGAAATGAGATTCCTTCGCTAGGAAGAG
CACTCGGAATAACCTGCTGGAAATGGGATTCCTTCGCTAGGAAGAGCACTCGGAATAACCTGCTGGAAATGAGATTCCTTCGCTAGGAAG
AGCACTCGGAATAACCTGCTGGAAATGGGATTCCTTCGCTAGGAAGAGCACTCGGAATAACCTGCTGGAAATGGGATTCCTTCGCTAGGA
AGAGCACTCGGAATAACCTGCTGGAAATGGGATTCCTTCCCTAGGAAGAGCACTCGGAATAACCTGCTGGAAATGAGATTCCTTCCCTAG
GAAGAGCACTCGGAATAACCTGCTGGAAATGGGATTCCTTCGCTAGGAAGAGCACTCGGAATAACCTGCTGGAAATGGGATTCCTTCGCT
AGGAAGAGCACTCAGAACAACCTGCCTGCTTGAGGGTGACAGCAAGTGTCTCACACTTCTCGTCTACTCCAAGTCAGATTCCTAAAAATA
AAATAGAGCTCCAATGGGCAATTTAAGCAAAAGCCTTAGAAACATGGACACCTGAAATGCTGGCCTACATGAAGGGTACGATGACATTTT
ATATATTAAATAAAAATTCCCAGTCCTGTTTTAGTATTCATCAGAATAGCCTCTTGGACCCTCGAAGTTCTACACCTTTGGGAGATATAA
ATTTCCTTAAAATAAAGGGATTGCTTCTTTGTGTAAATAGCTTTCATTTTCTCCATCTGGAAGTGATTTCTGCCTGCATGTTGGAGCACA
AAATACTGCAGTTAATTAAAGCATTACTGGATGTCATTTGCTAGAATGTATTTCCTTACTGCTGACAGAAAACAGAACAGACTCTAGGAA
AGAAGTAGCAAGTCCGTGACCCTGGCCGCTCCTGGTGGCTGCCCTTCTCCCTTCCCTGACAGTCTAAGGAAGCAACGCGTGGGAGCAGAA
TGTGGCCGACTGAGCCCAGTCCTGACCTGCCCAGTTGCAGTGGAGCCTGTCTGTAATGTTGTGTAAAGTGTTTTGCTTCTGACTTGGAAC
CCTACTTGCCCTGTGAATTTCTATCCTGTGAACCTTCCCTTCTCTGTCCTTACCGTTCCCATCACAGCCTGCTCTTCCAGTGACGGCCAA
GTGATTTCTCTCCTGCACGCATGAGTCCATCCTGTTTCCTTAGTAGCTGGATGGACGTTTTGCCATGAAAACTCTTTGGGAAGTCTTGTG
TCCTTTAGTGATTTCTCTCCTGCACGCATGAGTCCATCCTGTTTCCTTAGTAGCTGGTTGGACGTTTTTGCCATGAAAACTCTTCGGGAA
GTCCTGTGTCCTTTCAACAGGGGAAAACTGGCTGCGGCCCTTCCATTAGGCTCCAGGATCATTACCTCGTTTCCATTCTTTCTTTTCAAC
AGCTCCCCACTTTACTAGGGAAGCCAAGGGATCAACCTAATGAGAAAAGAACCTTCCCTGTAGCCCACCTGGAAGGGCATTGCCTGCCAG
CTCCTTCCTTCTCACCTATGTGAACAGGAGGGAAGATGCCGGCGATCCATGGATCTGTGGGACATGAAGGACGTGTCCATCAGAAATGAA
AGCAGCCTGGGATTGGAAGCATCCACAGAAGACTTGATCTGCAGGTCTTGATTTGGACCTGGCACTTTGACACCAGGCGAGTCACTGATC
CCCTGAGCATCCATTTTCAATATTGGTGAGAGGGGATTATAATGAATATTGGCTGTGAAGGTCACACAAGACCGGGCTATATGCACTTGC
TCTGCCATAAGGCAGTGTGAAGTGTGTTCGTGATCACTTGTGGGCGGGAGCCTGTGGCTGTCTTGCCTGGACTGGCTTTTTTAAACATGG
ATGAGTGGTGACAAATCCTGCGGCCGTGTGCAGGCTACATCCGCAGCGAGCTCCGCATATCTGGTCTTTGCCTTTTTAGGTCATGACTGT
AATATCAAGCTTACACGAGAGTTTTAAAAGACTGAGCAGTATCCCCTTCCCCTGGCAGCTGCTGCTTCCGTAGCATTTAGGGATAAACCT
GCAGACACTGAGAAGAGAGCTTCCTCCCTCCTGGGGCTGGTGGCGAGGCTGCCTGTTGTGGAAAATAGGGCATGTCTCCTGTGAATGCGA
ATTGCGAGGGTTGCCAAAGCCTCCCTTCCAAGAAACTTGCTTAGGTGTCTGGTGTCCACAGACCAGACTCTTCTCCCGACAGGGACAAAA
ATTCTTGCCTGCCTTTCTTTTTCTTTTTTTTCCTTTTACTTATTCTTGCCTTTTTTCTTCTTCTTCTTCTTTAGGTATGATGCCCCCCAA
AAAACTAAGCAAGATTAACTTGGGACAGGCAGTTCTAACTGGGAAGCCTGAGCTCACAGGCTGTTTGGATTACTTTCCAATTGTGTTTCA
AAGATGTTTAGACTTTTCCCAAGGCCAGCTGAATCCTTATAATCAGCCCAAAAGTTCCTTTCTGTTTCTGTCTGTCCCCTTTGAGGGTGT
TGACTCAGAGAACCTGGGGCAATATGAGATGTTAAAATAAAAATAGCGTCCAACGTCCCGCCTCCTGGGAATGCTGCTCACTTCATCCGA
GGGTTCTGGGAGCTTCTGCTCAGTCATCAAATGGAATTTGCACAATTGTCTTGCCTCCTGTTTTGGGTAATTTTTCAACAAGTGAGAAAT
TAAGAACAGCTTCTCAACAAACTTCCCTCTACTTCCAGGGCCAAGAAAAGTATTTGCAGTGTGGGCTGCAGCTTTCAGGGGTCTCAGGTG
AAATGGTGGCAAGAAACCCCAGCTCCCTTCATGTGTTTGCCTTGCGCTGATGGAAAAGGAAGGCACTTCTCAGCTGCCAGAGACCACATT
CCACAGGGTTCTTCACAAAATCAAGCACTGCAGTGGACCAACTGGAGCAGCCACTGGAGGGCTTTAGAAGGCAAATGGAATACATATCAA
ATGCTATATAAAGAAAACATCTGTTTACACAGAGTCCCCCACAGCCTCATACCTACACCCAATATCAAATGCTGTATAAAGAAACATCAG
TTTACACACAGAGCCCCCCACAACCTCATACCCACACCGAATATCAAATGCTATACAAAGAAACATCAGTTTACACACAGAGTCCCCCAC
AGCCTCATACCCATGCCTGTCACATCTTTGCACAGCCCTAAAGGATCCAGAGCTTTGGATCAGCAGCTGGCTAGCTCGGAGGCCAGAGGA
GGGTGCTGAGGGGAGTGGAGGTCAGTTGGGGTAGCCCTGGGCCCTGGCTGCACAGTCCAGCTGCTGTGTGGCCTGCATGTGGTATCTTAG
GTCATGAGAGGGCCTGGGCAATTCAGTGCTATCTGTACATGTTGGTGGGGTGGGAAGGAAAAGGTAACTGTGTATTTACTGTGTCCTGGA
TACATTATCTCATCGGATGAAATTCCTGCTAAGTTAAGCTCCGTTTAGTGGACGGGACTTGGAGGCTCAAAGAGGGTAAGTGACAGGCCC
AAGGATATGTGCCTAGTGAGGGGTGAGCCAGGATTCGATGTGTGACTAGTAAGGGGTCAGCCAGGATTCAATATGTGACTAGTAAGGGGT
CAGCCAGGATTTCATATGGGACTAGTAAGGGGTCGGCCAGGATTTGATACGTGACTAGCAAGGGGACAAGCCAGGATTTGATATGTGACT
AGTGAGGGGCGAGCCAGGATTCGATATGTGACTAGTAAGGGGTCAGCCAAGATTTGATATGTGACTAGTGAGGGGCGAGACAGGATTTGA
TATGTGACTAGTGAGGGGCGAGCCAGGATTTGATATGTGACTGGTGAGGGGCGAGCCAGGATTTGATATGTGACTGGTGAGGGGCGAGCC
AGGATTTGATATGTGACTGGTGAGGGGCGAGCCAGGATTTGATATGTGACTGGTGAGGGGCGAGCCAGGATTTGATATGTGACTGGTGAG
GGGCGAGCCAGGATTTGATATGTGACTGGTGAGGGGCGAGCCAGGATTTGATATGTGACTGGTGAGGGGCGAGCCAGGATTTGATATGTG
ACTGGTGAGGGGCGAGCCAGGATTTGATATGTGACTGGTGAGGGGCGAGCCAGGATTTGATATGTGACTGGTGAGGGGCGAGCCAGGATT
TGATATGTGACTGGTGAGGGGCGAGCCAGGATTTGATATGTGACTGGTGAGGGGTGGAGCCAGTCAGGATTTGATATGTGGTTAGTGAGG
GGTTAGCCAGTCAGGATTTGATATGTGGCTAGTGAGGGGCGAGCCAGGATTTGATATGTGACTAGTAAGGGGGTGAGCCAGGATTCAATA
CGTGACAAGTGAGGGGTGAGCCAGGATTCAATACGTGACCAGTGAGGGGCGAGCCAGGATTCGATACGTGACCAGTGAGGGGCGAGCCAG
GATGCGATACGTGACCAGTGAGGGGCGAGCCAGGATTCCATACGTGACTAGTGAGGGGTGAGCCAGGATTCGATATGTGAGTAGTGAGGA
GTGAGCCAGGATTTGATATGTGGCTACTGAGGGGCGAGCCAGGATTTGATATGTGACTAGTAAGGGGTCAGCCAGGATTTGATACGTGAC
TAGTCAGGGGGTCAGCCAGGATTCGATACGTGACTAGTAAGGGGTCAGCCAGGATTTGATATGTGACTAGTGAGGGGTGAGCCAGGATTT
GACATGTGACTAGTGAGGGGTGAGCCAGGATTCAATATGTGACTAGTGAGGGGTGAGCCAGGATTCGATATGTACCTAGTGAGGGGTCAG
CCAGGATTTGATATGTGGCTAGTAAGGGGTGAGCCAGCCAGGATTTGATATGTGACTAGTGACGAGTGAGCCAGGATTTGATATGTGACT
AGTAAGGGGGTGAGGCAGGATTTGATATGTGACTAGTAAGGGGGTGAGGCAGGATTTGATATGTGACTGGTGAGGGGTGAGACAGGATTT
GATATGTGACTAGTGAGGGGTGAGCCAGGATTTGCTATGTGACTAGTAAGGGGGCGAGCCAGGATTTGGCTCCAGCCTTCATTCCAACAT
CCATGCCTTTTGTACTTCACCAGCAGTTTTCAAATTTATGGGACAAAATTTTACATTGGATTCCCTCTATACAAAATAGATAAAAGTATT
TTATGAATACATTTTATGAGTTCAAATATTTTTCAGAAGAAATCAGTAAAAGCATTGAAAACTATTCCAGCAAATAGGAAGCACTTTAAA
CCAAGGTTATGGATGAAAATGTGTGTGTATCAACCCCAGTTTACTTCTGGGTTGCACAGAATAGAGAAATCTTGATTTAATCCAGCTAAG
AATTTTCAAATAGTATCCATTTTGTTTTGTTTTAAACAGCTCTTCTTGCAATGGTAGAGGCTCTTCAATTAAACAGAGATGGTAACAGGC

>60237_60237_4_NRD1-VPS53_NRD1_chr1_52258049_ENST00000354831_VPS53_chr17_440416_ENST00000437048_length(amino acids)=1219AA_BP=1009
MLRRVTVAAVCATRRKLCEAGRELAALWGIETRGRCEDSAAARPFPILAMPGRNKAKSTCSCPDLQPNGQDLGENSRVARLGADESEEEG
RRGSLSNAGDPEIVKSPSDPKQYRYIKLQNGLQALLISDLSNMEGKTGNTTDDEEEEEVEEEEEDDDEDSGAEIEDDDEEGFDDEDEFDD
EHDDDLDTEDNELEELEERAEARKKTTEKQQLQSLFLLWSKLTDRLWFKSTYSKMSSTLLVETRNLYGVVGAESRSAPVQHLAGWQAEEQ
QGETDTVLSAAALCVGVGSFADPDDLPGLAHFLEHMVFMGSLKYPDENGFDAFLKKHGGSDNASTDCERTVFQFDVQRKYFKEALDRWAQ
FFIHPLMIRDAIDREVEAVDSEYQLARPSDANRKEMLFGSLARPGHPMGKFFWGNAETLKHEPRKNNIDTHARLREFWMRYYSSHYMTLV
VQSKETLDTLEKWVTEIFSQIPNNGLPRPNFGHLTDPFDTPAFNKLYRVVPIRKIHALTITWALPPQQQHYRVKPLHYISWLVGHEGKGS
ILSFLRKKCWALALFGGNGETGFEQNSTYSVFSISITLTDEGYEHFYEVAYTVFQYLKMLQKLGPEKRIFEEIRKIEDNEFHYQEQTDPV
EYVENMCENMQLYPLQDILTGDQLLFEYKPEVIGEALNQLVPQKANLVLLSGANEGKCDLKEKWFGTQYSIEDIENSWAELWNSNFELNP
DLHLPAENKYIATDFTLKAFDCPETEYPVKIVNTPQGCLWYKKDNKFKIPKAYIRFHLISPLIQKSAANVVLFDIFVNILTHNLAEPAYE
ADVAQLEYKLVAGEHGLIIRVKGFNHKLPLLFQLIIDYLAEFNSTPAVFTMITEQLKKTYFNILIKPETLAKDVRLLILEYARWSMIDKY
QALMDGLSLESLLSFVKEFKSQLFVEGLVQGNVTSTESMDFLKYVVDKLNFKPLEQEMPVQFQVVELPSGHHLCKVKALNKGDANSEVTV
YYQSGTRSLREYTLMELLVMQWQNVEHVGDQSPYVTSVILHIKQNVPIIRDNLASTRKYFTQFCVKFANSFIPKFITHLFKCKPISMVGA
EQLLLDTHSLKMVLLDLPSISSQVVRKAPASYTKIVVKGMTRAEMILKVVMAPHEPLVVFVDNYIKLLTDCNTETFQKILDMKGLKRSEQ

--------------------------------------------------------------
>60237_60237_5_NRD1-VPS53_NRD1_chr1_52260144_ENST00000352171_VPS53_chr17_440416_ENST00000437048_length(transcript)=14058nt_BP=2965nt
AGTAGCGTCATCGGCGGCCGGGAGGGCGGAGGGACGAGGGAAGTCGGCGAGAGGGAGACTGGGTTGGGGGAGGGGTTCAGGCCTGTTCCC
CGCGGCTGCGGCAGCACCAGGGCCGGCCGCCACCGCCTCTAGAACGCGGAGGAGGTGGGTCCTGGGAAGCGGGATGTCCATCGCTCCAGC
TTGGTGGTGAATGCTGAGGAGAGTCACTGTTGCTGCAGTCTGTGCCACCCGGAGGAAGTTGTGTGAGGCCGGGCGGGAGCTCGCGGCGCT
CTGGGGAATCGAAACGCGGGGTCGGTGCGAAGACTCTGCTGCTGCCAGACCCTTTCCTATTCTGGCCATGCCTGGAAGGAACAAGGCGAA
GTCTACCTGCAGCTGCCCTGACCTGCAGCCCAATGGACAGGATCTGGGCGAGAACAGCCGGGTTGCCCGTCTAGGAGCGGATGAATCTGA
GGAAGAGGGACGGAGGGGGTCTCTCAGTAATGCTGGGGACCCTGAGATCGTCAAGTCTCCCAGCGACCCCAAGCAATACCGATACATCAA
ATTACAGAATGGCTTGCAGGCACTTCTGATTTCAGACCTAAGTAATATGGAAGGTAAAACAGGAAATACAACAGATGATGAAGAAGAAGA
GGAGGTGGAGGAAGAAGAAGAAGATGATGATGAAGATTCTGGAGCTGAAATAGAAGATGACGATGAAGAGGGTTTTGATGATGAAGATGA
GTTTGATGATGAACATGATGATGATCTTGATACTGAGGATAATGAATTGGAAGAATTAGAAGAGAGAGCAGAAGCTAGAAAAAAAACTAC
TGAAAAACAGTCTGCAGCGGCTCTTTGTGTTGGAGTTGGGAGTTTCGCTGATCCAGATGACCTGCCGGGGCTGGCACACTTTTTGGAGCA
CATGGTATTCATGGGTAGTTTGAAATATCCAGATGAGAATGGATTTGATGCCTTCCTGAAGAAGCATGGGGGTAGTGATAATGCCTCAAC
TGATTGTGAACGCACTGTCTTTCAGTTTGATGTCCAGAGGAAGTACTTCAAGGAAGCTCTTGATAGATGGGCGCAGTTCTTCATCCACCC
ACTAATGATCAGAGATGCAATTGACCGTGAAGTTGAAGCTGTTGATAGTGAATATCAACTTGCAAGGCCTTCTGATGCAAACAGAAAGGA
AATGTTGTTTGGAAGCCTTGCTAGACCTGGACATCCTATGGGAAAATTTTTTTGGGGAAATGCTGAGACGCTCAAGCATGAGCCAAGAAA
GAATAATATTGATACACATGCTAGATTGAGAGAATTCTGGATGCGTTACTACTCTTCTCATTACATGACTTTAGTGGTTCAATCCAAAGA
AACACTGGATACTTTGGAAAAGTGGGTGACTGAAATCTTCTCTCAGATACCAAACAATGGGTTACCCAGACCAAACTTTGGCCATTTAAC
GGATCCATTTGACACACCAGCATTTAACAAACTTTATAGAGTTGTTCCAATCAGAAAAATTCATGCTCTGACCATCACATGGGCACTTCC
TCCTCAACAGCAACATTACAGGGTGAAGCCACTTCATTATATATCCTGGCTGGTTGGACATGAAGGCAAAGGCAGCATTCTTTCTTTCCT
TAGGAAAAAATGCTGGGCTCTTGCACTGTTTGGTGGAAATGGTGAGACAGGATTTGAGCAAAATTCTACTTATTCAGTGTTCAGCATTTC
TATTACATTGACTGATGAGGGTTATGAACATTTTTATGAGGTTGCTTACACTGTCTTTCAGTATTTAAAAATGCTGCAGAAGCTAGGCCC
AGAAAAAAGAATTTTTGAAGAGATTCGGAAAATTGAGGATAATGAATTTCATTACCAAGAACAGACAGATCCAGTTGAGTATGTGGAAAA
CATGTGTGAGAACATGCAGCTGTACCCATTGCAGGACATTCTCACTGGAGATCAGCTTCTTTTTGAATACAAGCCAGAAGTCATTGGTGA
AGCCTTGAATCAGCTAGTTCCTCAAAAAGCAAATCTTGTTTTACTGTCTGGTGCTAATGAGGGAAAATGTGACCTCAAGGAGAAATGGTT
TGGAACTCAATATAGTATAGAAGATATTGAAAACTCTTGGGCTGAACTGTGGAATAGTAATTTCGAATTAAATCCAGATCTTCATCTTCC
AGCTGAAAACAAGTACATAGCCACGGACTTTACGTTGAAGGCTTTCGATTGCCCGGAAACAGAATACCCAGTTAAAATTGTGAATACTCC
ACAAGGTTGCCTGTGGTATAAGAAAGACAACAAATTCAAAATCCCCAAAGCATATATACGTTTCCATCTAATTTCACCGTTGATACAGAA
ATCTGCAGCAAATGTGGTCCTCTTTGATATCTTTGTCAATATCCTTACGCATAACCTTGCGGAACCAGCTTATGAAGCAGATGTGGCACA
GCTGGAGTATAAACTGGTAGCTGGAGAACATGGTTTAATTATTCGAGTGAAAGGATTTAACCACAAACTACCTCTACTGTTTCAGCTCAT
TATTGACTACTTAGCTGAGTTCAATTCCACACCAGCTGTCTTTACAATGATAACTGAGCAGTTGAAGAAGACCTACTTTAACATCCTCAT
CAAGCCCGAGACTTTGGCCAAAGATGTACGGCTTTTAATCTTGGAATATGCCCGTTGGTCTATGATTGACAAGTACCAGGCTTTGATGGA
CGGCCTTTCCCTTGAGTCTCTGCTGAGCTTCGTCAAAGAATTCAAATCCCAGCTCTTTGTGGAGGGCCTGGTACAAGGGAATGTCACAAG
CACAGAATCTATGGATTTCCTGAAATATGTTGTTGACAAACTAAACTTCAAGCCTCTGGAGCAGGAGATGCCTGTGCAGTTCCAGGTGGT
AGAGCTGCCCAGTGGCCACCATCTATGCAAAGTGAAAGCTCTGAACAAGGGTGATGCCAACTCTGAAGTCACTGTGTACTACCAGATGCA
GTGGCAGAACGTGGAGCACGTTGGTGACCAGAGCCCCTACGTCACCTCTGTCATTCTGCACATCAAGCAGAACGTCCCCATCATCCGTGA
CAACCTGGCTTCCACACGCAAGTACTTCACTCAGTTCTGCGTTAAATTTGCAAACTCCTTCATTCCCAAATTCATCACCCACCTCTTCAA
GTGCAAGCCAATTAGCATGGTGGGAGCAGAACAGCTGCTGCTGGACACCCACTCGCTGAAGATGGTCCTGCTCGATCTCCCCTCCATCAG
CTCGCAGGTGGTGAGGAAGGCACCCGCCAGCTACACCAAGATCGTTGTCAAAGGCATGACCCGGGCTGAGATGATCCTCAAGGTAGTGAT
GGCCCCTCATGAACCGTTGGTGGTGTTTGTTGACAACTACATCAAACTTCTCACAGACTGCAACACAGAAACCTTTCAGAAGATACTGGA
CATGAAGGGGCTGAAGAGGAGTGAGCAGAGCAGCATGCTGGAACTCCTGCGCCAGCGGCTCCCCGCACCGCCCTCGGGGGCAGAAAGCTC
CGGCTCACTGTCCCTGACGGCGCCAACACCAGAGCAAGAGTCGTCACGCATCCGCAAGCTCGAGAAACTCATTAAAAAGAGACTGTAGCA
GCAGCAAGGGGCCCTTTGCTCCTGGCTGGAGACCCTCAGCGCCCGTTCCCCAGAAGCCCCCAACCTCTCCTGTGCTCCCCGGCACTCTCA
CATCGTCGGTCTTCAAACTTCCTGGGACATGTGGGTTGTTACTGAGTCTCTCCCATGCCCTGTCTTACTTCCTGCCCTAATCGGAGACGC
TGAGTAAGGGCTGGGCTCTAAGAGGGCGATTTAGGTGATCTCTGGTTCGTGAAGCAGAGGCAGCAGTGGAGGATAGGTCCCTGAGCTGCC
CTTGACTCATGTAGCCTCCCCATGGCAGTCACACCCTCTTGACACGTGGGCCCCACCCGTCCTTTTTTTTTTTTTTTTTTTTTTTTTTTG
AGACAGAGTCTCGCTCTGTCACCCAGGCTGGAGTGCAGTGGCGTGATCTCGGCTCACTGCAACCTCCGCCTCCCAGGTTCAAGCAATTCT
CCTGCCTCAGCCTCCTGAGTATCGGATTACAGGCGTGAGCCACCGAGCCCAGCCCCTTCCTCCATTTCTTTACTCCCACCCTGCTCCTGG
TTTCTAGGGAAGGGAAACCAGGAAGTTCACTTGGAAGACGTTTCCTAGGTTTTCTCATCAGATGAAGCCATGGGAACGCCCAGGAAGTCC
ATACTCTCAAACCCCTTTCTGCCCACTCACCTTCAGGTCCACAGCACTTTCCAGCGTCATCTGAAATAGCAAAGGTGATGTGCAGCATCC
CAGTGATGTGTTCCTGTGTTATGAGAAGGAGTCTGGGGTTCTGGATGCCTCAGGAACAGAATATGGACCTTAAAGACCAGGCTGAGAGCC
TGGCCTGGCACGCAGCCTGCCCGCCCCCCCCGCCCTTCCTGTCCACCGCGGGCTCTCTGCAGCAGGGCTTGCCGAAGAGACTGCTCCCGA
CCTCTCATGTCATCCTGCATCCAGAGAATGGCAGCATATCAAGCCGTTAACCCTGATTCACTCGGTTCCCTTGAAACCAGGCCTCAGTTA
ACCATGACCACAGCTACAGGCAAACCGCTGCTGTTGCTGCCTGCTTTTGCTGAAGAATGATATCTTGCCAGGCACGGCGGCTCATGCCTG
TAGTCGCAACACTTTGGGAGACCAAGGCAGGAGGATCACTTGAGTCCAGGAGTTTGAGACCAGCCTGGGCAACATACAGATGTCTACAAA
AATAAAAATTTGCAAGGTGTGGTGGCATGCACCTGTAGTCCCAACTGCTAGGGAGGCTGAGGTGGGCAGATTGCTTGAGCTCAGGAGTTT
GAGACCAGTCTGGGCAACCTGGCAAAACCAAAAATACAAAAAATTGGCTGGGTGTGGTGGCTCATGCCTGTAATCACAGCACTTTGGGAG
GCTGAGGCAGGTGGATCACCTGAGGTCAGGAATTCGAGACCAGCCTGCCCAACATGGCGAAACCCTGTCTCAACTAAAAATAAAAAAAAT
TAGCCGGGTGTCATGGCGAGTGCCTGTAATCCCAGCTACTGGGGAGGCTGAGGCAGGAGAATCACTTAAACCCGGGAGGTGGAGGCTGCA
GTGAGCCAAGATTTCACCACTGCACTCCAGCCTGGGTGACAGAGCAAGACCCCTTCTCAAAAAGTTTTCAGGATAGAGGAAATTTCCTTA
AAATCCATAAAACTTGTAACAGCCGTACAGTAGGAATAAGGTTTGGAAATCTGCCTGGAAACCTGATTTCCTCATCCCCACCTTGTTTCC
CAACATAACCACTGCTCTGTGCCCCTGCCCTCTCTGCCAGGCTTTCTCCCCGATGCCGTCCAGCTCTGATCCTGAGTGTCATTTCTTCAT
CGGCTTCCAGGCTGTCCTTGCTAGCTGGTTTGACTCTCACGCATCAAGCGTCTCAAATTTGAGAATGCGGAGGAGAAAAGAAGTGTTGCG
AGAAGGAGATGCGGCCTTCAGTTGAGGTCTATTAGGAAAAGATTCCAAATAAGACAAGGGCGGGGGGCGGCAGTCGGGAGAGCCCCCAGG
AAGCCCTGTAGATGCCCCCACCCCAGCCCATGGAGTTGCTATGGTTAAGCAGCCTGAGCCGTACAGTTGAAAAGGGGCGGTGGGGCCCAT
CTCCAAATAGCACAGCCAGTTCAGCCGTCTGTCCTCAACCCAGGAGAGCTGGGAAAGCCAGTGGACTCCTGCACCTGGTTCTTGTCACTC
CTGGCGTTTGTGTACAGATCACCACTTCTCTTTTTGGTTCATTGTTGAGGAGTCGTTTTCCGGACGGCTCCATCACAGCATTGAGCTATC
AAGCTGCTGTTTTCCACAGTTGGTGGTCACAGCCAGGGAAGTTGCTGTCTTGATTTGTTACATTGTCAGTAATCCCCAAGGAACCAATGG
ATGTCAGTAGGAGTTTCTGTTAAATGTCTCCTTGATGGGGACTCAGTACTGTGTAGAGACGCTGTGTTTCTCTTCTGGGGGTGTGCATCA
GAACCACTGGGGCCTTTTAAAATCTACAGATGCCGGCCGGGCGCCGTGGCTCACGCCTGGAATCCCAGCACTTGGGGAGGCTGAGGCGGG
CGGATCACAAGCGCAGGAAATTGAGACCATCCTTGCCAATATGGTGAAACCCCATCTCTACAAAAAATACAAAAATTACCGGGGTGTGGT
GGCGTGCACACCTCCCAGCTACTTGGGAGGCTGAGGCAGGAGAATCGCTTGAACCCGGGAGGCAAAGATTGCAGTGAGCCGAGATCACGC
CACTGCACTCCAGCCTGGCGACAGAGTGAGACTCTATCTCAAAACAAACAAAAAAACAGATGCCCGGAGATTTTGAGTCAGTAAGTTTGG
ATGGGGCCTGGCATACAGGTTTAAAAGTTCCATAGGTAGTTATAACGTTTACACCTTGTTAAGAACCACTGCAACAGAGAGATTTGCTTT
ATGGAAGGGCTCCTGCCACGCATTTTCATACATGTCTATTTTTCTGACTCTAAGCTAAAAGTGCGCCGACACTACACTTGAGCTGGTGCC
AACGTGGTGAAGATTCTCTACTGATAACAGCTTTCATTTTAAACTTGTGTTGGGTCAGGCGCGGTGGCTCACGCCTGTAATCCCAGCACT
TTGGGAGGCCGAGGTGGGCGGATCACATGAGGTCACGAGTTTGAGACCAGCCTGGCCAACATGGCAAAATCCCATCTCTACTAAAAATAC
AAAAAAAAAAAAAAAAAAAGCAGGCAGGTGGCGGGTGCCTGTAATCCCAGCTACTTGGGAGGCTGAGGCAGGGGAATCAGTTGAATCCGG
GAGGCGGAGGTTGCAGTGAGCCGAGGTCCCGCCACTGCACTCCAGCCTGGGAGACAGAGTGAGACTCAGTTAAAAAAAAAAGACTTTTGG
TGGTGGTGGGGACCATGCCCAGGATTGGGCTCTCTCCATACTGATGAGGATTCTTCTTGTTTTGATGACCAACCCCCAAGCAGAAGCTTT
ATTTATTAACATCACTTCAAAAATAACGTATCAAAGGGGCACCCTAGGCCGGGTACTGTGGCATCACACCTGTAATGCCAGTGCTTTGAG
AGGCTGAGGTGGGAAGATTGCTTGAGCCCAGGACTTCAAGACAAGCCTGGGCAACAGAGTGAGACCCCATCTCTATTAAAAAATAGGCCG
GGCATGGTGGCTCACACTGGTAATCCCAGCACTTTGGGAGGCCGAGGCAGGTGGATCATGTGAGGTCAGGAGTTCGAGACCAGCCTGGCC
GACATGGTGAAACCCTGTCTTTACTAAAAATACAAAATTAGCCAGGCGTGGTGGTGGGCGCCTGTAATCCCAGCTACTCAGGAGGCTGAA
GCAGGAGGATCGCTTGAACCCAGGAGGCAGAGGCTGCAGTGAGCCGAGATCATGCCATTGCACTCCTGCCTGGGTGACGGAGCAAGACTC
TCTAAAAAATAATAAGGTAAAAGGAGTACCTGTGGATGAAAGCAGCAGCTAACAGCTCTGTGATTCAGCTAGACCTAGATATTGTGCCCA
TTCCTTCCCCTCAGTCCATTTTCTGTAGCCCCTTTAAAAACCAAAAAACAACTTTGAAGTCACTTTGGGTTTAAAATAAATAGTGGTAAT
TTGTATAATCAATAAAGAGTTCACTCTGCTCTTACTGAGGGGACTTGTCTGAAAGCTGGCTTAGCGGTGTCCAGGCCAGAGAACATCCTG
TGTGGACTCTTAACAATGAAACAGGAGCCGCAATGGACAAGGTGTTCTGATCTCCAAACCCAGCTCAGGGATTGAAGCTAACTACCGCCA
CTCCTTCCTCTCTCGAAGAACAAAGAGCCAGTACCCAGGGCTCTGCCCACCCCCGAGAAGGGGTGCCTGATTTCTTATGTCTAGGGTGGC
TCCTCTGTGCAGATCAGACAGGACTGAGAGCAGACAAGCTGAGACCAGCATGACCAGTACAGGGCACGCAGAGCGTGGGGGCAGGTCCGA
GGCTGCTGCTCGATGCAGGGTATGACACCAACCCTTCCTGAATTGCCATCGGATGAGGAGACCTGGTTCCCTGTTGAAAGAATGCCAGGG
GAAATGCTGCATGTGCACAGCTGGAAATGGGGTTCCTTCTCTAGGAAGAGCACTCGGAATAACCTGCTGGAAATGGGGTTCCTTCCCTAG
GAAGAGCACTCAGAATAACCTGCTGGAAATGGGATTCCTTGGCTAGGAAGAGCACTCAGAATAACCTGCTGGAAATGGGATTCCTTGGCT
AGGAAGAGCACTCAGAATAACCTGCTGGAAATGGGATTCCTTACCTAGGAAGAGCACTCGGAATAACCTGCTGGAAATGGGATTCCTTAC
CTAGGAAGAGCACTCGGAATAACCTGCTGGAAATGGGGTTCCTTCCCTAGGAAGAGCACTCGGAATAACCTGCTGGAAATGGGGTTCCTT
CCCTAGGAAGAGCACTCGGAATAACCTGCTGGAAATGGGGTTCCTTCGCTAGGAAGAGCACTCGGAATAACCTGCTGGAAATGGGATTCC
TTCGCTAGGAAGAGCACTCGGAATAACCTGCTGGAAATGGGATTCCTTCGCTAGGAAGAGCACTCGGAATAACCTGCTGGAAATGAGATT
CCTTCCCTAGGAAGAGCACTCGGAATAACCTGCTGGAAATGGGATTCCTTCGCTAGGAAGAGCACTCGGAATAACCTGCTGGAAATGAGA
TTCCTTCGCTAGGAAGAGCACTCGGAATAACCTGCTGGAAATGGGATTCCTTCGCTAGGAAGAGCACTCGGAATAACCTGCTGGAAATGA
GATTCCTTCGCTAGGAAGAGCACTCGGAATAACCTGCTGGAAATGGGATTCCTTCGCTAGGAAGAGCACTCGGAATAACCTGCTGGAAAT
GGGATTCCTTCGCTAGGAAGAGCACTCGGAATAACCTGCTGGAAATGGGATTCCTTCCCTAGGAAGAGCACTCGGAATAACCTGCTGGAA
ATGAGATTCCTTCCCTAGGAAGAGCACTCGGAATAACCTGCTGGAAATGGGATTCCTTCGCTAGGAAGAGCACTCGGAATAACCTGCTGG
AAATGGGATTCCTTCGCTAGGAAGAGCACTCAGAACAACCTGCCTGCTTGAGGGTGACAGCAAGTGTCTCACACTTCTCGTCTACTCCAA
GTCAGATTCCTAAAAATAAAATAGAGCTCCAATGGGCAATTTAAGCAAAAGCCTTAGAAACATGGACACCTGAAATGCTGGCCTACATGA
AGGGTACGATGACATTTTATATATTAAATAAAAATTCCCAGTCCTGTTTTAGTATTCATCAGAATAGCCTCTTGGACCCTCGAAGTTCTA
CACCTTTGGGAGATATAAATTTCCTTAAAATAAAGGGATTGCTTCTTTGTGTAAATAGCTTTCATTTTCTCCATCTGGAAGTGATTTCTG
CCTGCATGTTGGAGCACAAAATACTGCAGTTAATTAAAGCATTACTGGATGTCATTTGCTAGAATGTATTTCCTTACTGCTGACAGAAAA
CAGAACAGACTCTAGGAAAGAAGTAGCAAGTCCGTGACCCTGGCCGCTCCTGGTGGCTGCCCTTCTCCCTTCCCTGACAGTCTAAGGAAG
CAACGCGTGGGAGCAGAATGTGGCCGACTGAGCCCAGTCCTGACCTGCCCAGTTGCAGTGGAGCCTGTCTGTAATGTTGTGTAAAGTGTT
TTGCTTCTGACTTGGAACCCTACTTGCCCTGTGAATTTCTATCCTGTGAACCTTCCCTTCTCTGTCCTTACCGTTCCCATCACAGCCTGC
TCTTCCAGTGACGGCCAAGTGATTTCTCTCCTGCACGCATGAGTCCATCCTGTTTCCTTAGTAGCTGGATGGACGTTTTGCCATGAAAAC
TCTTTGGGAAGTCTTGTGTCCTTTAGTGATTTCTCTCCTGCACGCATGAGTCCATCCTGTTTCCTTAGTAGCTGGTTGGACGTTTTTGCC
ATGAAAACTCTTCGGGAAGTCCTGTGTCCTTTCAACAGGGGAAAACTGGCTGCGGCCCTTCCATTAGGCTCCAGGATCATTACCTCGTTT
CCATTCTTTCTTTTCAACAGCTCCCCACTTTACTAGGGAAGCCAAGGGATCAACCTAATGAGAAAAGAACCTTCCCTGTAGCCCACCTGG
AAGGGCATTGCCTGCCAGCTCCTTCCTTCTCACCTATGTGAACAGGAGGGAAGATGCCGGCGATCCATGGATCTGTGGGACATGAAGGAC
GTGTCCATCAGAAATGAAAGCAGCCTGGGATTGGAAGCATCCACAGAAGACTTGATCTGCAGGTCTTGATTTGGACCTGGCACTTTGACA
CCAGGCGAGTCACTGATCCCCTGAGCATCCATTTTCAATATTGGTGAGAGGGGATTATAATGAATATTGGCTGTGAAGGTCACACAAGAC
CGGGCTATATGCACTTGCTCTGCCATAAGGCAGTGTGAAGTGTGTTCGTGATCACTTGTGGGCGGGAGCCTGTGGCTGTCTTGCCTGGAC
TGGCTTTTTTAAACATGGATGAGTGGTGACAAATCCTGCGGCCGTGTGCAGGCTACATCCGCAGCGAGCTCCGCATATCTGGTCTTTGCC
TTTTTAGGTCATGACTGTAATATCAAGCTTACACGAGAGTTTTAAAAGACTGAGCAGTATCCCCTTCCCCTGGCAGCTGCTGCTTCCGTA
GCATTTAGGGATAAACCTGCAGACACTGAGAAGAGAGCTTCCTCCCTCCTGGGGCTGGTGGCGAGGCTGCCTGTTGTGGAAAATAGGGCA
TGTCTCCTGTGAATGCGAATTGCGAGGGTTGCCAAAGCCTCCCTTCCAAGAAACTTGCTTAGGTGTCTGGTGTCCACAGACCAGACTCTT
CTCCCGACAGGGACAAAAATTCTTGCCTGCCTTTCTTTTTCTTTTTTTTCCTTTTACTTATTCTTGCCTTTTTTCTTCTTCTTCTTCTTT
AGGTATGATGCCCCCCAAAAAACTAAGCAAGATTAACTTGGGACAGGCAGTTCTAACTGGGAAGCCTGAGCTCACAGGCTGTTTGGATTA
CTTTCCAATTGTGTTTCAAAGATGTTTAGACTTTTCCCAAGGCCAGCTGAATCCTTATAATCAGCCCAAAAGTTCCTTTCTGTTTCTGTC
TGTCCCCTTTGAGGGTGTTGACTCAGAGAACCTGGGGCAATATGAGATGTTAAAATAAAAATAGCGTCCAACGTCCCGCCTCCTGGGAAT
GCTGCTCACTTCATCCGAGGGTTCTGGGAGCTTCTGCTCAGTCATCAAATGGAATTTGCACAATTGTCTTGCCTCCTGTTTTGGGTAATT
TTTCAACAAGTGAGAAATTAAGAACAGCTTCTCAACAAACTTCCCTCTACTTCCAGGGCCAAGAAAAGTATTTGCAGTGTGGGCTGCAGC
TTTCAGGGGTCTCAGGTGAAATGGTGGCAAGAAACCCCAGCTCCCTTCATGTGTTTGCCTTGCGCTGATGGAAAAGGAAGGCACTTCTCA
GCTGCCAGAGACCACATTCCACAGGGTTCTTCACAAAATCAAGCACTGCAGTGGACCAACTGGAGCAGCCACTGGAGGGCTTTAGAAGGC
AAATGGAATACATATCAAATGCTATATAAAGAAAACATCTGTTTACACAGAGTCCCCCACAGCCTCATACCTACACCCAATATCAAATGC
TGTATAAAGAAACATCAGTTTACACACAGAGCCCCCCACAACCTCATACCCACACCGAATATCAAATGCTATACAAAGAAACATCAGTTT
ACACACAGAGTCCCCCACAGCCTCATACCCATGCCTGTCACATCTTTGCACAGCCCTAAAGGATCCAGAGCTTTGGATCAGCAGCTGGCT
AGCTCGGAGGCCAGAGGAGGGTGCTGAGGGGAGTGGAGGTCAGTTGGGGTAGCCCTGGGCCCTGGCTGCACAGTCCAGCTGCTGTGTGGC
CTGCATGTGGTATCTTAGGTCATGAGAGGGCCTGGGCAATTCAGTGCTATCTGTACATGTTGGTGGGGTGGGAAGGAAAAGGTAACTGTG
TATTTACTGTGTCCTGGATACATTATCTCATCGGATGAAATTCCTGCTAAGTTAAGCTCCGTTTAGTGGACGGGACTTGGAGGCTCAAAG
AGGGTAAGTGACAGGCCCAAGGATATGTGCCTAGTGAGGGGTGAGCCAGGATTCGATGTGTGACTAGTAAGGGGTCAGCCAGGATTCAAT
ATGTGACTAGTAAGGGGTCAGCCAGGATTTCATATGGGACTAGTAAGGGGTCGGCCAGGATTTGATACGTGACTAGCAAGGGGACAAGCC
AGGATTTGATATGTGACTAGTGAGGGGCGAGCCAGGATTCGATATGTGACTAGTAAGGGGTCAGCCAAGATTTGATATGTGACTAGTGAG
GGGCGAGACAGGATTTGATATGTGACTAGTGAGGGGCGAGCCAGGATTTGATATGTGACTGGTGAGGGGCGAGCCAGGATTTGATATGTG
ACTGGTGAGGGGCGAGCCAGGATTTGATATGTGACTGGTGAGGGGCGAGCCAGGATTTGATATGTGACTGGTGAGGGGCGAGCCAGGATT
TGATATGTGACTGGTGAGGGGCGAGCCAGGATTTGATATGTGACTGGTGAGGGGCGAGCCAGGATTTGATATGTGACTGGTGAGGGGCGA
GCCAGGATTTGATATGTGACTGGTGAGGGGCGAGCCAGGATTTGATATGTGACTGGTGAGGGGCGAGCCAGGATTTGATATGTGACTGGT
GAGGGGCGAGCCAGGATTTGATATGTGACTGGTGAGGGGCGAGCCAGGATTTGATATGTGACTGGTGAGGGGTGGAGCCAGTCAGGATTT
GATATGTGGTTAGTGAGGGGTTAGCCAGTCAGGATTTGATATGTGGCTAGTGAGGGGCGAGCCAGGATTTGATATGTGACTAGTAAGGGG
GTGAGCCAGGATTCAATACGTGACAAGTGAGGGGTGAGCCAGGATTCAATACGTGACCAGTGAGGGGCGAGCCAGGATTCGATACGTGAC
CAGTGAGGGGCGAGCCAGGATGCGATACGTGACCAGTGAGGGGCGAGCCAGGATTCCATACGTGACTAGTGAGGGGTGAGCCAGGATTCG
ATATGTGAGTAGTGAGGAGTGAGCCAGGATTTGATATGTGGCTACTGAGGGGCGAGCCAGGATTTGATATGTGACTAGTAAGGGGTCAGC
CAGGATTTGATACGTGACTAGTCAGGGGGTCAGCCAGGATTCGATACGTGACTAGTAAGGGGTCAGCCAGGATTTGATATGTGACTAGTG
AGGGGTGAGCCAGGATTTGACATGTGACTAGTGAGGGGTGAGCCAGGATTCAATATGTGACTAGTGAGGGGTGAGCCAGGATTCGATATG
TACCTAGTGAGGGGTCAGCCAGGATTTGATATGTGGCTAGTAAGGGGTGAGCCAGCCAGGATTTGATATGTGACTAGTGACGAGTGAGCC
AGGATTTGATATGTGACTAGTAAGGGGGTGAGGCAGGATTTGATATGTGACTAGTAAGGGGGTGAGGCAGGATTTGATATGTGACTGGTG
AGGGGTGAGACAGGATTTGATATGTGACTAGTGAGGGGTGAGCCAGGATTTGCTATGTGACTAGTAAGGGGGCGAGCCAGGATTTGGCTC
CAGCCTTCATTCCAACATCCATGCCTTTTGTACTTCACCAGCAGTTTTCAAATTTATGGGACAAAATTTTACATTGGATTCCCTCTATAC
AAAATAGATAAAAGTATTTTATGAATACATTTTATGAGTTCAAATATTTTTCAGAAGAAATCAGTAAAAGCATTGAAAACTATTCCAGCA
AATAGGAAGCACTTTAAACCAAGGTTATGGATGAAAATGTGTGTGTATCAACCCCAGTTTACTTCTGGGTTGCACAGAATAGAGAAATCT
TGATTTAATCCAGCTAAGAATTTTCAAATAGTATCCATTTTGTTTTGTTTTAAACAGCTCTTCTTGCAATGGTAGAGGCTCTTCAATTAA

>60237_60237_5_NRD1-VPS53_NRD1_chr1_52260144_ENST00000352171_VPS53_chr17_440416_ENST00000437048_length(amino acids)=1135AA_BP=924
MLRRVTVAAVCATRRKLCEAGRELAALWGIETRGRCEDSAAARPFPILAMPGRNKAKSTCSCPDLQPNGQDLGENSRVARLGADESEEEG
RRGSLSNAGDPEIVKSPSDPKQYRYIKLQNGLQALLISDLSNMEGKTGNTTDDEEEEEVEEEEEDDDEDSGAEIEDDDEEGFDDEDEFDD
EHDDDLDTEDNELEELEERAEARKKTTEKQSAAALCVGVGSFADPDDLPGLAHFLEHMVFMGSLKYPDENGFDAFLKKHGGSDNASTDCE
RTVFQFDVQRKYFKEALDRWAQFFIHPLMIRDAIDREVEAVDSEYQLARPSDANRKEMLFGSLARPGHPMGKFFWGNAETLKHEPRKNNI
DTHARLREFWMRYYSSHYMTLVVQSKETLDTLEKWVTEIFSQIPNNGLPRPNFGHLTDPFDTPAFNKLYRVVPIRKIHALTITWALPPQQ
QHYRVKPLHYISWLVGHEGKGSILSFLRKKCWALALFGGNGETGFEQNSTYSVFSISITLTDEGYEHFYEVAYTVFQYLKMLQKLGPEKR
IFEEIRKIEDNEFHYQEQTDPVEYVENMCENMQLYPLQDILTGDQLLFEYKPEVIGEALNQLVPQKANLVLLSGANEGKCDLKEKWFGTQ
YSIEDIENSWAELWNSNFELNPDLHLPAENKYIATDFTLKAFDCPETEYPVKIVNTPQGCLWYKKDNKFKIPKAYIRFHLISPLIQKSAA
NVVLFDIFVNILTHNLAEPAYEADVAQLEYKLVAGEHGLIIRVKGFNHKLPLLFQLIIDYLAEFNSTPAVFTMITEQLKKTYFNILIKPE
TLAKDVRLLILEYARWSMIDKYQALMDGLSLESLLSFVKEFKSQLFVEGLVQGNVTSTESMDFLKYVVDKLNFKPLEQEMPVQFQVVELP
SGHHLCKVKALNKGDANSEVTVYYQMQWQNVEHVGDQSPYVTSVILHIKQNVPIIRDNLASTRKYFTQFCVKFANSFIPKFITHLFKCKP
ISMVGAEQLLLDTHSLKMVLLDLPSISSQVVRKAPASYTKIVVKGMTRAEMILKVVMAPHEPLVVFVDNYIKLLTDCNTETFQKILDMKG

--------------------------------------------------------------
>60237_60237_6_NRD1-VPS53_NRD1_chr1_52260144_ENST00000354831_VPS53_chr17_440416_ENST00000437048_length(transcript)=14262nt_BP=3169nt
AGTAGCGTCATCGGCGGCCGGGAGGGCGGAGGGACGAGGGAAGTCGGCGAGAGGGAGACTGGGTTGGGGGAGGGGTTCAGGCCTGTTCCC
CGCGGCTGCGGCAGCACCAGGGCCGGCCGCCACCGCCTCTAGAACGCGGAGGAGGTGGGTCCTGGGAAGCGGGATGTCCATCGCTCCAGC
TTGGTGGTGAATGCTGAGGAGAGTCACTGTTGCTGCAGTCTGTGCCACCCGGAGGAAGTTGTGTGAGGCCGGGCGGGAGCTCGCGGCGCT
CTGGGGAATCGAAACGCGGGGTCGGTGCGAAGACTCTGCTGCTGCCAGACCCTTTCCTATTCTGGCCATGCCTGGAAGGAACAAGGCGAA
GTCTACCTGCAGCTGCCCTGACCTGCAGCCCAATGGACAGGATCTGGGCGAGAACAGCCGGGTTGCCCGTCTAGGAGCGGATGAATCTGA
GGAAGAGGGACGGAGGGGGTCTCTCAGTAATGCTGGGGACCCTGAGATCGTCAAGTCTCCCAGCGACCCCAAGCAATACCGATACATCAA
ATTACAGAATGGCTTGCAGGCACTTCTGATTTCAGACCTAAGTAATATGGAAGGTAAAACAGGAAATACAACAGATGATGAAGAAGAAGA
GGAGGTGGAGGAAGAAGAAGAAGATGATGATGAAGATTCTGGAGCTGAAATAGAAGATGACGATGAAGAGGGTTTTGATGATGAAGATGA
GTTTGATGATGAACATGATGATGATCTTGATACTGAGGATAATGAATTGGAAGAATTAGAAGAGAGAGCAGAAGCTAGAAAAAAAACTAC
TGAAAAACAGCAATTGCAGAGCCTGTTTTTGCTGTGGTCAAAGCTGACTGATAGACTGTGGTTTAAGTCAACTTATTCAAAAATGTCTTC
AACCCTGCTGGTCGAGACAAGAAATCTTTATGGGGTAGTTGGAGCTGAAAGCAGGTCTGCACCTGTTCAGCATTTGGCAGGATGGCAAGC
GGAGGAGCAGCAGGGTGAAACTGACACAGTTCTGTCTGCAGCGGCTCTTTGTGTTGGAGTTGGGAGTTTCGCTGATCCAGATGACCTGCC
GGGGCTGGCACACTTTTTGGAGCACATGGTATTCATGGGTAGTTTGAAATATCCAGATGAGAATGGATTTGATGCCTTCCTGAAGAAGCA
TGGGGGTAGTGATAATGCCTCAACTGATTGTGAACGCACTGTCTTTCAGTTTGATGTCCAGAGGAAGTACTTCAAGGAAGCTCTTGATAG
ATGGGCGCAGTTCTTCATCCACCCACTAATGATCAGAGATGCAATTGACCGTGAAGTTGAAGCTGTTGATAGTGAATATCAACTTGCAAG
GCCTTCTGATGCAAACAGAAAGGAAATGTTGTTTGGAAGCCTTGCTAGACCTGGACATCCTATGGGAAAATTTTTTTGGGGAAATGCTGA
GACGCTCAAGCATGAGCCAAGAAAGAATAATATTGATACACATGCTAGATTGAGAGAATTCTGGATGCGTTACTACTCTTCTCATTACAT
GACTTTAGTGGTTCAATCCAAAGAAACACTGGATACTTTGGAAAAGTGGGTGACTGAAATCTTCTCTCAGATACCAAACAATGGGTTACC
CAGACCAAACTTTGGCCATTTAACGGATCCATTTGACACACCAGCATTTAACAAACTTTATAGAGTTGTTCCAATCAGAAAAATTCATGC
TCTGACCATCACATGGGCACTTCCTCCTCAACAGCAACATTACAGGGTGAAGCCACTTCATTATATATCCTGGCTGGTTGGACATGAAGG
CAAAGGCAGCATTCTTTCTTTCCTTAGGAAAAAATGCTGGGCTCTTGCACTGTTTGGTGGAAATGGTGAGACAGGATTTGAGCAAAATTC
TACTTATTCAGTGTTCAGCATTTCTATTACATTGACTGATGAGGGTTATGAACATTTTTATGAGGTTGCTTACACTGTCTTTCAGTATTT
AAAAATGCTGCAGAAGCTAGGCCCAGAAAAAAGAATTTTTGAAGAGATTCGGAAAATTGAGGATAATGAATTTCATTACCAAGAACAGAC
AGATCCAGTTGAGTATGTGGAAAACATGTGTGAGAACATGCAGCTGTACCCATTGCAGGACATTCTCACTGGAGATCAGCTTCTTTTTGA
ATACAAGCCAGAAGTCATTGGTGAAGCCTTGAATCAGCTAGTTCCTCAAAAAGCAAATCTTGTTTTACTGTCTGGTGCTAATGAGGGAAA
ATGTGACCTCAAGGAGAAATGGTTTGGAACTCAATATAGTATAGAAGATATTGAAAACTCTTGGGCTGAACTGTGGAATAGTAATTTCGA
ATTAAATCCAGATCTTCATCTTCCAGCTGAAAACAAGTACATAGCCACGGACTTTACGTTGAAGGCTTTCGATTGCCCGGAAACAGAATA
CCCAGTTAAAATTGTGAATACTCCACAAGGTTGCCTGTGGTATAAGAAAGACAACAAATTCAAAATCCCCAAAGCATATATACGTTTCCA
TCTAATTTCACCGTTGATACAGAAATCTGCAGCAAATGTGGTCCTCTTTGATATCTTTGTCAATATCCTTACGCATAACCTTGCGGAACC
AGCTTATGAAGCAGATGTGGCACAGCTGGAGTATAAACTGGTAGCTGGAGAACATGGTTTAATTATTCGAGTGAAAGGATTTAACCACAA
ACTACCTCTACTGTTTCAGCTCATTATTGACTACTTAGCTGAGTTCAATTCCACACCAGCTGTCTTTACAATGATAACTGAGCAGTTGAA
GAAGACCTACTTTAACATCCTCATCAAGCCCGAGACTTTGGCCAAAGATGTACGGCTTTTAATCTTGGAATATGCCCGTTGGTCTATGAT
TGACAAGTACCAGGCTTTGATGGACGGCCTTTCCCTTGAGTCTCTGCTGAGCTTCGTCAAAGAATTCAAATCCCAGCTCTTTGTGGAGGG
CCTGGTACAAGGGAATGTCACAAGCACAGAATCTATGGATTTCCTGAAATATGTTGTTGACAAACTAAACTTCAAGCCTCTGGAGCAGGA
GATGCCTGTGCAGTTCCAGGTGGTAGAGCTGCCCAGTGGCCACCATCTATGCAAAGTGAAAGCTCTGAACAAGGGTGATGCCAACTCTGA
AGTCACTGTGTACTACCAGATGCAGTGGCAGAACGTGGAGCACGTTGGTGACCAGAGCCCCTACGTCACCTCTGTCATTCTGCACATCAA
GCAGAACGTCCCCATCATCCGTGACAACCTGGCTTCCACACGCAAGTACTTCACTCAGTTCTGCGTTAAATTTGCAAACTCCTTCATTCC
CAAATTCATCACCCACCTCTTCAAGTGCAAGCCAATTAGCATGGTGGGAGCAGAACAGCTGCTGCTGGACACCCACTCGCTGAAGATGGT
CCTGCTCGATCTCCCCTCCATCAGCTCGCAGGTGGTGAGGAAGGCACCCGCCAGCTACACCAAGATCGTTGTCAAAGGCATGACCCGGGC
TGAGATGATCCTCAAGGTAGTGATGGCCCCTCATGAACCGTTGGTGGTGTTTGTTGACAACTACATCAAACTTCTCACAGACTGCAACAC
AGAAACCTTTCAGAAGATACTGGACATGAAGGGGCTGAAGAGGAGTGAGCAGAGCAGCATGCTGGAACTCCTGCGCCAGCGGCTCCCCGC
ACCGCCCTCGGGGGCAGAAAGCTCCGGCTCACTGTCCCTGACGGCGCCAACACCAGAGCAAGAGTCGTCACGCATCCGCAAGCTCGAGAA
ACTCATTAAAAAGAGACTGTAGCAGCAGCAAGGGGCCCTTTGCTCCTGGCTGGAGACCCTCAGCGCCCGTTCCCCAGAAGCCCCCAACCT
CTCCTGTGCTCCCCGGCACTCTCACATCGTCGGTCTTCAAACTTCCTGGGACATGTGGGTTGTTACTGAGTCTCTCCCATGCCCTGTCTT
ACTTCCTGCCCTAATCGGAGACGCTGAGTAAGGGCTGGGCTCTAAGAGGGCGATTTAGGTGATCTCTGGTTCGTGAAGCAGAGGCAGCAG
TGGAGGATAGGTCCCTGAGCTGCCCTTGACTCATGTAGCCTCCCCATGGCAGTCACACCCTCTTGACACGTGGGCCCCACCCGTCCTTTT
TTTTTTTTTTTTTTTTTTTTTTTGAGACAGAGTCTCGCTCTGTCACCCAGGCTGGAGTGCAGTGGCGTGATCTCGGCTCACTGCAACCTC
CGCCTCCCAGGTTCAAGCAATTCTCCTGCCTCAGCCTCCTGAGTATCGGATTACAGGCGTGAGCCACCGAGCCCAGCCCCTTCCTCCATT
TCTTTACTCCCACCCTGCTCCTGGTTTCTAGGGAAGGGAAACCAGGAAGTTCACTTGGAAGACGTTTCCTAGGTTTTCTCATCAGATGAA
GCCATGGGAACGCCCAGGAAGTCCATACTCTCAAACCCCTTTCTGCCCACTCACCTTCAGGTCCACAGCACTTTCCAGCGTCATCTGAAA
TAGCAAAGGTGATGTGCAGCATCCCAGTGATGTGTTCCTGTGTTATGAGAAGGAGTCTGGGGTTCTGGATGCCTCAGGAACAGAATATGG
ACCTTAAAGACCAGGCTGAGAGCCTGGCCTGGCACGCAGCCTGCCCGCCCCCCCCGCCCTTCCTGTCCACCGCGGGCTCTCTGCAGCAGG
GCTTGCCGAAGAGACTGCTCCCGACCTCTCATGTCATCCTGCATCCAGAGAATGGCAGCATATCAAGCCGTTAACCCTGATTCACTCGGT
TCCCTTGAAACCAGGCCTCAGTTAACCATGACCACAGCTACAGGCAAACCGCTGCTGTTGCTGCCTGCTTTTGCTGAAGAATGATATCTT
GCCAGGCACGGCGGCTCATGCCTGTAGTCGCAACACTTTGGGAGACCAAGGCAGGAGGATCACTTGAGTCCAGGAGTTTGAGACCAGCCT
GGGCAACATACAGATGTCTACAAAAATAAAAATTTGCAAGGTGTGGTGGCATGCACCTGTAGTCCCAACTGCTAGGGAGGCTGAGGTGGG
CAGATTGCTTGAGCTCAGGAGTTTGAGACCAGTCTGGGCAACCTGGCAAAACCAAAAATACAAAAAATTGGCTGGGTGTGGTGGCTCATG
CCTGTAATCACAGCACTTTGGGAGGCTGAGGCAGGTGGATCACCTGAGGTCAGGAATTCGAGACCAGCCTGCCCAACATGGCGAAACCCT
GTCTCAACTAAAAATAAAAAAAATTAGCCGGGTGTCATGGCGAGTGCCTGTAATCCCAGCTACTGGGGAGGCTGAGGCAGGAGAATCACT
TAAACCCGGGAGGTGGAGGCTGCAGTGAGCCAAGATTTCACCACTGCACTCCAGCCTGGGTGACAGAGCAAGACCCCTTCTCAAAAAGTT
TTCAGGATAGAGGAAATTTCCTTAAAATCCATAAAACTTGTAACAGCCGTACAGTAGGAATAAGGTTTGGAAATCTGCCTGGAAACCTGA
TTTCCTCATCCCCACCTTGTTTCCCAACATAACCACTGCTCTGTGCCCCTGCCCTCTCTGCCAGGCTTTCTCCCCGATGCCGTCCAGCTC
TGATCCTGAGTGTCATTTCTTCATCGGCTTCCAGGCTGTCCTTGCTAGCTGGTTTGACTCTCACGCATCAAGCGTCTCAAATTTGAGAAT
GCGGAGGAGAAAAGAAGTGTTGCGAGAAGGAGATGCGGCCTTCAGTTGAGGTCTATTAGGAAAAGATTCCAAATAAGACAAGGGCGGGGG
GCGGCAGTCGGGAGAGCCCCCAGGAAGCCCTGTAGATGCCCCCACCCCAGCCCATGGAGTTGCTATGGTTAAGCAGCCTGAGCCGTACAG
TTGAAAAGGGGCGGTGGGGCCCATCTCCAAATAGCACAGCCAGTTCAGCCGTCTGTCCTCAACCCAGGAGAGCTGGGAAAGCCAGTGGAC
TCCTGCACCTGGTTCTTGTCACTCCTGGCGTTTGTGTACAGATCACCACTTCTCTTTTTGGTTCATTGTTGAGGAGTCGTTTTCCGGACG
GCTCCATCACAGCATTGAGCTATCAAGCTGCTGTTTTCCACAGTTGGTGGTCACAGCCAGGGAAGTTGCTGTCTTGATTTGTTACATTGT
CAGTAATCCCCAAGGAACCAATGGATGTCAGTAGGAGTTTCTGTTAAATGTCTCCTTGATGGGGACTCAGTACTGTGTAGAGACGCTGTG
TTTCTCTTCTGGGGGTGTGCATCAGAACCACTGGGGCCTTTTAAAATCTACAGATGCCGGCCGGGCGCCGTGGCTCACGCCTGGAATCCC
AGCACTTGGGGAGGCTGAGGCGGGCGGATCACAAGCGCAGGAAATTGAGACCATCCTTGCCAATATGGTGAAACCCCATCTCTACAAAAA
ATACAAAAATTACCGGGGTGTGGTGGCGTGCACACCTCCCAGCTACTTGGGAGGCTGAGGCAGGAGAATCGCTTGAACCCGGGAGGCAAA
GATTGCAGTGAGCCGAGATCACGCCACTGCACTCCAGCCTGGCGACAGAGTGAGACTCTATCTCAAAACAAACAAAAAAACAGATGCCCG
GAGATTTTGAGTCAGTAAGTTTGGATGGGGCCTGGCATACAGGTTTAAAAGTTCCATAGGTAGTTATAACGTTTACACCTTGTTAAGAAC
CACTGCAACAGAGAGATTTGCTTTATGGAAGGGCTCCTGCCACGCATTTTCATACATGTCTATTTTTCTGACTCTAAGCTAAAAGTGCGC
CGACACTACACTTGAGCTGGTGCCAACGTGGTGAAGATTCTCTACTGATAACAGCTTTCATTTTAAACTTGTGTTGGGTCAGGCGCGGTG
GCTCACGCCTGTAATCCCAGCACTTTGGGAGGCCGAGGTGGGCGGATCACATGAGGTCACGAGTTTGAGACCAGCCTGGCCAACATGGCA
AAATCCCATCTCTACTAAAAATACAAAAAAAAAAAAAAAAAAAGCAGGCAGGTGGCGGGTGCCTGTAATCCCAGCTACTTGGGAGGCTGA
GGCAGGGGAATCAGTTGAATCCGGGAGGCGGAGGTTGCAGTGAGCCGAGGTCCCGCCACTGCACTCCAGCCTGGGAGACAGAGTGAGACT
CAGTTAAAAAAAAAAGACTTTTGGTGGTGGTGGGGACCATGCCCAGGATTGGGCTCTCTCCATACTGATGAGGATTCTTCTTGTTTTGAT
GACCAACCCCCAAGCAGAAGCTTTATTTATTAACATCACTTCAAAAATAACGTATCAAAGGGGCACCCTAGGCCGGGTACTGTGGCATCA
CACCTGTAATGCCAGTGCTTTGAGAGGCTGAGGTGGGAAGATTGCTTGAGCCCAGGACTTCAAGACAAGCCTGGGCAACAGAGTGAGACC
CCATCTCTATTAAAAAATAGGCCGGGCATGGTGGCTCACACTGGTAATCCCAGCACTTTGGGAGGCCGAGGCAGGTGGATCATGTGAGGT
CAGGAGTTCGAGACCAGCCTGGCCGACATGGTGAAACCCTGTCTTTACTAAAAATACAAAATTAGCCAGGCGTGGTGGTGGGCGCCTGTA
ATCCCAGCTACTCAGGAGGCTGAAGCAGGAGGATCGCTTGAACCCAGGAGGCAGAGGCTGCAGTGAGCCGAGATCATGCCATTGCACTCC
TGCCTGGGTGACGGAGCAAGACTCTCTAAAAAATAATAAGGTAAAAGGAGTACCTGTGGATGAAAGCAGCAGCTAACAGCTCTGTGATTC
AGCTAGACCTAGATATTGTGCCCATTCCTTCCCCTCAGTCCATTTTCTGTAGCCCCTTTAAAAACCAAAAAACAACTTTGAAGTCACTTT
GGGTTTAAAATAAATAGTGGTAATTTGTATAATCAATAAAGAGTTCACTCTGCTCTTACTGAGGGGACTTGTCTGAAAGCTGGCTTAGCG
GTGTCCAGGCCAGAGAACATCCTGTGTGGACTCTTAACAATGAAACAGGAGCCGCAATGGACAAGGTGTTCTGATCTCCAAACCCAGCTC
AGGGATTGAAGCTAACTACCGCCACTCCTTCCTCTCTCGAAGAACAAAGAGCCAGTACCCAGGGCTCTGCCCACCCCCGAGAAGGGGTGC
CTGATTTCTTATGTCTAGGGTGGCTCCTCTGTGCAGATCAGACAGGACTGAGAGCAGACAAGCTGAGACCAGCATGACCAGTACAGGGCA
CGCAGAGCGTGGGGGCAGGTCCGAGGCTGCTGCTCGATGCAGGGTATGACACCAACCCTTCCTGAATTGCCATCGGATGAGGAGACCTGG
TTCCCTGTTGAAAGAATGCCAGGGGAAATGCTGCATGTGCACAGCTGGAAATGGGGTTCCTTCTCTAGGAAGAGCACTCGGAATAACCTG
CTGGAAATGGGGTTCCTTCCCTAGGAAGAGCACTCAGAATAACCTGCTGGAAATGGGATTCCTTGGCTAGGAAGAGCACTCAGAATAACC
TGCTGGAAATGGGATTCCTTGGCTAGGAAGAGCACTCAGAATAACCTGCTGGAAATGGGATTCCTTACCTAGGAAGAGCACTCGGAATAA
CCTGCTGGAAATGGGATTCCTTACCTAGGAAGAGCACTCGGAATAACCTGCTGGAAATGGGGTTCCTTCCCTAGGAAGAGCACTCGGAAT
AACCTGCTGGAAATGGGGTTCCTTCCCTAGGAAGAGCACTCGGAATAACCTGCTGGAAATGGGGTTCCTTCGCTAGGAAGAGCACTCGGA
ATAACCTGCTGGAAATGGGATTCCTTCGCTAGGAAGAGCACTCGGAATAACCTGCTGGAAATGGGATTCCTTCGCTAGGAAGAGCACTCG
GAATAACCTGCTGGAAATGAGATTCCTTCCCTAGGAAGAGCACTCGGAATAACCTGCTGGAAATGGGATTCCTTCGCTAGGAAGAGCACT
CGGAATAACCTGCTGGAAATGAGATTCCTTCGCTAGGAAGAGCACTCGGAATAACCTGCTGGAAATGGGATTCCTTCGCTAGGAAGAGCA
CTCGGAATAACCTGCTGGAAATGAGATTCCTTCGCTAGGAAGAGCACTCGGAATAACCTGCTGGAAATGGGATTCCTTCGCTAGGAAGAG
CACTCGGAATAACCTGCTGGAAATGGGATTCCTTCGCTAGGAAGAGCACTCGGAATAACCTGCTGGAAATGGGATTCCTTCCCTAGGAAG
AGCACTCGGAATAACCTGCTGGAAATGAGATTCCTTCCCTAGGAAGAGCACTCGGAATAACCTGCTGGAAATGGGATTCCTTCGCTAGGA
AGAGCACTCGGAATAACCTGCTGGAAATGGGATTCCTTCGCTAGGAAGAGCACTCAGAACAACCTGCCTGCTTGAGGGTGACAGCAAGTG
TCTCACACTTCTCGTCTACTCCAAGTCAGATTCCTAAAAATAAAATAGAGCTCCAATGGGCAATTTAAGCAAAAGCCTTAGAAACATGGA
CACCTGAAATGCTGGCCTACATGAAGGGTACGATGACATTTTATATATTAAATAAAAATTCCCAGTCCTGTTTTAGTATTCATCAGAATA
GCCTCTTGGACCCTCGAAGTTCTACACCTTTGGGAGATATAAATTTCCTTAAAATAAAGGGATTGCTTCTTTGTGTAAATAGCTTTCATT
TTCTCCATCTGGAAGTGATTTCTGCCTGCATGTTGGAGCACAAAATACTGCAGTTAATTAAAGCATTACTGGATGTCATTTGCTAGAATG
TATTTCCTTACTGCTGACAGAAAACAGAACAGACTCTAGGAAAGAAGTAGCAAGTCCGTGACCCTGGCCGCTCCTGGTGGCTGCCCTTCT
CCCTTCCCTGACAGTCTAAGGAAGCAACGCGTGGGAGCAGAATGTGGCCGACTGAGCCCAGTCCTGACCTGCCCAGTTGCAGTGGAGCCT
GTCTGTAATGTTGTGTAAAGTGTTTTGCTTCTGACTTGGAACCCTACTTGCCCTGTGAATTTCTATCCTGTGAACCTTCCCTTCTCTGTC
CTTACCGTTCCCATCACAGCCTGCTCTTCCAGTGACGGCCAAGTGATTTCTCTCCTGCACGCATGAGTCCATCCTGTTTCCTTAGTAGCT
GGATGGACGTTTTGCCATGAAAACTCTTTGGGAAGTCTTGTGTCCTTTAGTGATTTCTCTCCTGCACGCATGAGTCCATCCTGTTTCCTT
AGTAGCTGGTTGGACGTTTTTGCCATGAAAACTCTTCGGGAAGTCCTGTGTCCTTTCAACAGGGGAAAACTGGCTGCGGCCCTTCCATTA
GGCTCCAGGATCATTACCTCGTTTCCATTCTTTCTTTTCAACAGCTCCCCACTTTACTAGGGAAGCCAAGGGATCAACCTAATGAGAAAA
GAACCTTCCCTGTAGCCCACCTGGAAGGGCATTGCCTGCCAGCTCCTTCCTTCTCACCTATGTGAACAGGAGGGAAGATGCCGGCGATCC
ATGGATCTGTGGGACATGAAGGACGTGTCCATCAGAAATGAAAGCAGCCTGGGATTGGAAGCATCCACAGAAGACTTGATCTGCAGGTCT
TGATTTGGACCTGGCACTTTGACACCAGGCGAGTCACTGATCCCCTGAGCATCCATTTTCAATATTGGTGAGAGGGGATTATAATGAATA
TTGGCTGTGAAGGTCACACAAGACCGGGCTATATGCACTTGCTCTGCCATAAGGCAGTGTGAAGTGTGTTCGTGATCACTTGTGGGCGGG
AGCCTGTGGCTGTCTTGCCTGGACTGGCTTTTTTAAACATGGATGAGTGGTGACAAATCCTGCGGCCGTGTGCAGGCTACATCCGCAGCG
AGCTCCGCATATCTGGTCTTTGCCTTTTTAGGTCATGACTGTAATATCAAGCTTACACGAGAGTTTTAAAAGACTGAGCAGTATCCCCTT
CCCCTGGCAGCTGCTGCTTCCGTAGCATTTAGGGATAAACCTGCAGACACTGAGAAGAGAGCTTCCTCCCTCCTGGGGCTGGTGGCGAGG
CTGCCTGTTGTGGAAAATAGGGCATGTCTCCTGTGAATGCGAATTGCGAGGGTTGCCAAAGCCTCCCTTCCAAGAAACTTGCTTAGGTGT
CTGGTGTCCACAGACCAGACTCTTCTCCCGACAGGGACAAAAATTCTTGCCTGCCTTTCTTTTTCTTTTTTTTCCTTTTACTTATTCTTG
CCTTTTTTCTTCTTCTTCTTCTTTAGGTATGATGCCCCCCAAAAAACTAAGCAAGATTAACTTGGGACAGGCAGTTCTAACTGGGAAGCC
TGAGCTCACAGGCTGTTTGGATTACTTTCCAATTGTGTTTCAAAGATGTTTAGACTTTTCCCAAGGCCAGCTGAATCCTTATAATCAGCC
CAAAAGTTCCTTTCTGTTTCTGTCTGTCCCCTTTGAGGGTGTTGACTCAGAGAACCTGGGGCAATATGAGATGTTAAAATAAAAATAGCG
TCCAACGTCCCGCCTCCTGGGAATGCTGCTCACTTCATCCGAGGGTTCTGGGAGCTTCTGCTCAGTCATCAAATGGAATTTGCACAATTG
TCTTGCCTCCTGTTTTGGGTAATTTTTCAACAAGTGAGAAATTAAGAACAGCTTCTCAACAAACTTCCCTCTACTTCCAGGGCCAAGAAA
AGTATTTGCAGTGTGGGCTGCAGCTTTCAGGGGTCTCAGGTGAAATGGTGGCAAGAAACCCCAGCTCCCTTCATGTGTTTGCCTTGCGCT
GATGGAAAAGGAAGGCACTTCTCAGCTGCCAGAGACCACATTCCACAGGGTTCTTCACAAAATCAAGCACTGCAGTGGACCAACTGGAGC
AGCCACTGGAGGGCTTTAGAAGGCAAATGGAATACATATCAAATGCTATATAAAGAAAACATCTGTTTACACAGAGTCCCCCACAGCCTC
ATACCTACACCCAATATCAAATGCTGTATAAAGAAACATCAGTTTACACACAGAGCCCCCCACAACCTCATACCCACACCGAATATCAAA
TGCTATACAAAGAAACATCAGTTTACACACAGAGTCCCCCACAGCCTCATACCCATGCCTGTCACATCTTTGCACAGCCCTAAAGGATCC
AGAGCTTTGGATCAGCAGCTGGCTAGCTCGGAGGCCAGAGGAGGGTGCTGAGGGGAGTGGAGGTCAGTTGGGGTAGCCCTGGGCCCTGGC
TGCACAGTCCAGCTGCTGTGTGGCCTGCATGTGGTATCTTAGGTCATGAGAGGGCCTGGGCAATTCAGTGCTATCTGTACATGTTGGTGG
GGTGGGAAGGAAAAGGTAACTGTGTATTTACTGTGTCCTGGATACATTATCTCATCGGATGAAATTCCTGCTAAGTTAAGCTCCGTTTAG
TGGACGGGACTTGGAGGCTCAAAGAGGGTAAGTGACAGGCCCAAGGATATGTGCCTAGTGAGGGGTGAGCCAGGATTCGATGTGTGACTA
GTAAGGGGTCAGCCAGGATTCAATATGTGACTAGTAAGGGGTCAGCCAGGATTTCATATGGGACTAGTAAGGGGTCGGCCAGGATTTGAT
ACGTGACTAGCAAGGGGACAAGCCAGGATTTGATATGTGACTAGTGAGGGGCGAGCCAGGATTCGATATGTGACTAGTAAGGGGTCAGCC
AAGATTTGATATGTGACTAGTGAGGGGCGAGACAGGATTTGATATGTGACTAGTGAGGGGCGAGCCAGGATTTGATATGTGACTGGTGAG
GGGCGAGCCAGGATTTGATATGTGACTGGTGAGGGGCGAGCCAGGATTTGATATGTGACTGGTGAGGGGCGAGCCAGGATTTGATATGTG
ACTGGTGAGGGGCGAGCCAGGATTTGATATGTGACTGGTGAGGGGCGAGCCAGGATTTGATATGTGACTGGTGAGGGGCGAGCCAGGATT
TGATATGTGACTGGTGAGGGGCGAGCCAGGATTTGATATGTGACTGGTGAGGGGCGAGCCAGGATTTGATATGTGACTGGTGAGGGGCGA
GCCAGGATTTGATATGTGACTGGTGAGGGGCGAGCCAGGATTTGATATGTGACTGGTGAGGGGCGAGCCAGGATTTGATATGTGACTGGT
GAGGGGTGGAGCCAGTCAGGATTTGATATGTGGTTAGTGAGGGGTTAGCCAGTCAGGATTTGATATGTGGCTAGTGAGGGGCGAGCCAGG
ATTTGATATGTGACTAGTAAGGGGGTGAGCCAGGATTCAATACGTGACAAGTGAGGGGTGAGCCAGGATTCAATACGTGACCAGTGAGGG
GCGAGCCAGGATTCGATACGTGACCAGTGAGGGGCGAGCCAGGATGCGATACGTGACCAGTGAGGGGCGAGCCAGGATTCCATACGTGAC
TAGTGAGGGGTGAGCCAGGATTCGATATGTGAGTAGTGAGGAGTGAGCCAGGATTTGATATGTGGCTACTGAGGGGCGAGCCAGGATTTG
ATATGTGACTAGTAAGGGGTCAGCCAGGATTTGATACGTGACTAGTCAGGGGGTCAGCCAGGATTCGATACGTGACTAGTAAGGGGTCAG
CCAGGATTTGATATGTGACTAGTGAGGGGTGAGCCAGGATTTGACATGTGACTAGTGAGGGGTGAGCCAGGATTCAATATGTGACTAGTG
AGGGGTGAGCCAGGATTCGATATGTACCTAGTGAGGGGTCAGCCAGGATTTGATATGTGGCTAGTAAGGGGTGAGCCAGCCAGGATTTGA
TATGTGACTAGTGACGAGTGAGCCAGGATTTGATATGTGACTAGTAAGGGGGTGAGGCAGGATTTGATATGTGACTAGTAAGGGGGTGAG
GCAGGATTTGATATGTGACTGGTGAGGGGTGAGACAGGATTTGATATGTGACTAGTGAGGGGTGAGCCAGGATTTGCTATGTGACTAGTA
AGGGGGCGAGCCAGGATTTGGCTCCAGCCTTCATTCCAACATCCATGCCTTTTGTACTTCACCAGCAGTTTTCAAATTTATGGGACAAAA
TTTTACATTGGATTCCCTCTATACAAAATAGATAAAAGTATTTTATGAATACATTTTATGAGTTCAAATATTTTTCAGAAGAAATCAGTA
AAAGCATTGAAAACTATTCCAGCAAATAGGAAGCACTTTAAACCAAGGTTATGGATGAAAATGTGTGTGTATCAACCCCAGTTTACTTCT
GGGTTGCACAGAATAGAGAAATCTTGATTTAATCCAGCTAAGAATTTTCAAATAGTATCCATTTTGTTTTGTTTTAAACAGCTCTTCTTG

>60237_60237_6_NRD1-VPS53_NRD1_chr1_52260144_ENST00000354831_VPS53_chr17_440416_ENST00000437048_length(amino acids)=1203AA_BP=992
MLRRVTVAAVCATRRKLCEAGRELAALWGIETRGRCEDSAAARPFPILAMPGRNKAKSTCSCPDLQPNGQDLGENSRVARLGADESEEEG
RRGSLSNAGDPEIVKSPSDPKQYRYIKLQNGLQALLISDLSNMEGKTGNTTDDEEEEEVEEEEEDDDEDSGAEIEDDDEEGFDDEDEFDD
EHDDDLDTEDNELEELEERAEARKKTTEKQQLQSLFLLWSKLTDRLWFKSTYSKMSSTLLVETRNLYGVVGAESRSAPVQHLAGWQAEEQ
QGETDTVLSAAALCVGVGSFADPDDLPGLAHFLEHMVFMGSLKYPDENGFDAFLKKHGGSDNASTDCERTVFQFDVQRKYFKEALDRWAQ
FFIHPLMIRDAIDREVEAVDSEYQLARPSDANRKEMLFGSLARPGHPMGKFFWGNAETLKHEPRKNNIDTHARLREFWMRYYSSHYMTLV
VQSKETLDTLEKWVTEIFSQIPNNGLPRPNFGHLTDPFDTPAFNKLYRVVPIRKIHALTITWALPPQQQHYRVKPLHYISWLVGHEGKGS
ILSFLRKKCWALALFGGNGETGFEQNSTYSVFSISITLTDEGYEHFYEVAYTVFQYLKMLQKLGPEKRIFEEIRKIEDNEFHYQEQTDPV
EYVENMCENMQLYPLQDILTGDQLLFEYKPEVIGEALNQLVPQKANLVLLSGANEGKCDLKEKWFGTQYSIEDIENSWAELWNSNFELNP
DLHLPAENKYIATDFTLKAFDCPETEYPVKIVNTPQGCLWYKKDNKFKIPKAYIRFHLISPLIQKSAANVVLFDIFVNILTHNLAEPAYE
ADVAQLEYKLVAGEHGLIIRVKGFNHKLPLLFQLIIDYLAEFNSTPAVFTMITEQLKKTYFNILIKPETLAKDVRLLILEYARWSMIDKY
QALMDGLSLESLLSFVKEFKSQLFVEGLVQGNVTSTESMDFLKYVVDKLNFKPLEQEMPVQFQVVELPSGHHLCKVKALNKGDANSEVTV
YYQMQWQNVEHVGDQSPYVTSVILHIKQNVPIIRDNLASTRKYFTQFCVKFANSFIPKFITHLFKCKPISMVGAEQLLLDTHSLKMVLLD
LPSISSQVVRKAPASYTKIVVKGMTRAEMILKVVMAPHEPLVVFVDNYIKLLTDCNTETFQKILDMKGLKRSEQSSMLELLRQRLPAPPS

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Fusion Gene PPI Analysis for NRD1-VPS53


check button Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in

ChiPPI page.


check button Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160)
HgeneHgene's interactorsTgeneTgene's interactors


check button - Retained PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenStill interaction with


check button - Lost PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


check button - Retained PPIs, but lost function due to frame-shift fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


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Related Drugs for NRD1-VPS53


check button Drugs targeting genes involved in this fusion gene.
(DrugBank Version 5.1.8 2021-05-08)
PartnerGeneUniProtAccDrugBank IDDrug nameDrug activityDrug typeDrug status

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Related Diseases for NRD1-VPS53


check button Diseases associated with fusion partners.
(DisGeNet 4.0)
PartnerGeneDisease IDDisease name# pubmedsSource