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Center for Computational Systems Medicine
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Fusion Gene Summary

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Fusion Gene ORF analysis

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Fusion Genomic Features

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Fusion Protein Features

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Fusion Gene Sequence

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Fusion Gene PPI analysis

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Related Drugs

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Related Diseases

Fusion gene:NRP1-RSU1 (FusionGDB2 ID:60346)

Fusion Gene Summary for NRP1-RSU1

check button Fusion gene summary
Fusion gene informationFusion gene name: NRP1-RSU1
Fusion gene ID: 60346
HgeneTgene
Gene symbol

NRP1

RSU1

Gene ID

8829

6251

Gene nameneuropilin 1Ras suppressor protein 1
SynonymsBDCA4|CD304|NP1|NRP|VEGF165RRSP-1
Cytomap

10p11.22

10p13

Type of geneprotein-codingprotein-coding
Descriptionneuropilin-1transmembrane receptorvascular endothelial cell growth factor 165 receptorras suppressor protein 1ras suppressor protein 1 variant 1ras suppressor protein 1 variant 2ras suppressor protein 1 variant 3ras suppressor protein 1 variant 5rsu-1
Modification date2020032220200327
UniProtAcc

O14786

.
Ensembl transtripts involved in fusion geneENST00000265371, ENST00000374816, 
ENST00000374821, ENST00000374822, 
ENST00000374823, ENST00000374867, 
ENST00000395995, ENST00000432372, 
ENST00000374875, 
ENST00000464074, 
ENST00000345264, ENST00000377921, 
ENST00000602389, 
Fusion gene scores* DoF score13 X 9 X 6=70212 X 9 X 4=432
# samples 1412
** MAII scorelog2(14/702*10)=-2.32604420335959
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0
log2(12/432*10)=-1.84799690655495
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0
Context

PubMed: NRP1 [Title/Abstract] AND RSU1 [Title/Abstract] AND fusion [Title/Abstract]

Most frequent breakpointNRP1(33619636)-RSU1(16635495), # samples:1
Anticipated loss of major functional domain due to fusion event.NRP1-RSU1 seems lost the major protein functional domain in Hgene partner, which is a IUPHAR drug target due to the frame-shifted ORF.
NRP1-RSU1 seems lost the major protein functional domain in Tgene partner, which is a essential gene due to the frame-shifted ORF.
* DoF score (Degree of Frequency) = # partners X # break points X # cancer types
** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)

check button Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez
PartnerGeneGO IDGO termPubMed ID
HgeneNRP1

GO:0051894

positive regulation of focal adhesion assembly

24863063


check buttonFusion gene breakpoints across NRP1 (5'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check buttonFusion gene breakpoints across RSU1 (3'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check button Fusion gene information from two resources (ChiTars 5.0 and ChimerDB 4.0)
* All genome coordinats were lifted-over on hg19.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
SourceDiseaseSampleHgeneHchrHbpHstrandTgeneTchrTbpTstrand
ChimerDB4STADTCGA-BR-8364-01ANRP1chr10

33619636

-RSU1chr10

16635495

-


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Fusion Gene ORF analysis for NRP1-RSU1

check button Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
ORFHenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrand
5CDS-5UTRENST00000265371ENST00000464074NRP1chr10

33619636

-RSU1chr10

16635495

-
5CDS-5UTRENST00000374816ENST00000464074NRP1chr10

33619636

-RSU1chr10

16635495

-
5CDS-5UTRENST00000374821ENST00000464074NRP1chr10

33619636

-RSU1chr10

16635495

-
5CDS-5UTRENST00000374822ENST00000464074NRP1chr10

33619636

-RSU1chr10

16635495

-
5CDS-5UTRENST00000374823ENST00000464074NRP1chr10

33619636

-RSU1chr10

16635495

-
5CDS-5UTRENST00000374867ENST00000464074NRP1chr10

33619636

-RSU1chr10

16635495

-
5CDS-5UTRENST00000395995ENST00000464074NRP1chr10

33619636

-RSU1chr10

16635495

-
5CDS-5UTRENST00000432372ENST00000464074NRP1chr10

33619636

-RSU1chr10

16635495

-
5UTR-3CDSENST00000374875ENST00000345264NRP1chr10

33619636

-RSU1chr10

16635495

-
5UTR-3CDSENST00000374875ENST00000377921NRP1chr10

33619636

-RSU1chr10

16635495

-
5UTR-3CDSENST00000374875ENST00000602389NRP1chr10

33619636

-RSU1chr10

16635495

-
5UTR-5UTRENST00000374875ENST00000464074NRP1chr10

33619636

-RSU1chr10

16635495

-
Frame-shiftENST00000265371ENST00000377921NRP1chr10

33619636

-RSU1chr10

16635495

-
Frame-shiftENST00000265371ENST00000602389NRP1chr10

33619636

-RSU1chr10

16635495

-
Frame-shiftENST00000374816ENST00000345264NRP1chr10

33619636

-RSU1chr10

16635495

-
Frame-shiftENST00000374816ENST00000602389NRP1chr10

33619636

-RSU1chr10

16635495

-
Frame-shiftENST00000374821ENST00000345264NRP1chr10

33619636

-RSU1chr10

16635495

-
Frame-shiftENST00000374821ENST00000602389NRP1chr10

33619636

-RSU1chr10

16635495

-
Frame-shiftENST00000374822ENST00000345264NRP1chr10

33619636

-RSU1chr10

16635495

-
Frame-shiftENST00000374822ENST00000602389NRP1chr10

33619636

-RSU1chr10

16635495

-
Frame-shiftENST00000374823ENST00000345264NRP1chr10

33619636

-RSU1chr10

16635495

-
Frame-shiftENST00000374823ENST00000602389NRP1chr10

33619636

-RSU1chr10

16635495

-
Frame-shiftENST00000374867ENST00000345264NRP1chr10

33619636

-RSU1chr10

16635495

-
Frame-shiftENST00000374867ENST00000602389NRP1chr10

33619636

-RSU1chr10

16635495

-
Frame-shiftENST00000395995ENST00000345264NRP1chr10

33619636

-RSU1chr10

16635495

-
Frame-shiftENST00000395995ENST00000602389NRP1chr10

33619636

-RSU1chr10

16635495

-
Frame-shiftENST00000432372ENST00000345264NRP1chr10

33619636

-RSU1chr10

16635495

-
Frame-shiftENST00000432372ENST00000377921NRP1chr10

33619636

-RSU1chr10

16635495

-
In-frameENST00000265371ENST00000345264NRP1chr10

33619636

-RSU1chr10

16635495

-
In-frameENST00000374816ENST00000377921NRP1chr10

33619636

-RSU1chr10

16635495

-
In-frameENST00000374821ENST00000377921NRP1chr10

33619636

-RSU1chr10

16635495

-
In-frameENST00000374822ENST00000377921NRP1chr10

33619636

-RSU1chr10

16635495

-
In-frameENST00000374823ENST00000377921NRP1chr10

33619636

-RSU1chr10

16635495

-
In-frameENST00000374867ENST00000377921NRP1chr10

33619636

-RSU1chr10

16635495

-
In-frameENST00000395995ENST00000377921NRP1chr10

33619636

-RSU1chr10

16635495

-
In-frameENST00000432372ENST00000602389NRP1chr10

33619636

-RSU1chr10

16635495

-

check buttonORFfinder result based on the fusion transcript sequence of in-frame fusion genes.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandSeq length
(transcript)
BP loci
(transcript)
Predicted start
(transcript)
Predicted stop
(transcript)
Seq length
(amino acids)
ENST00000265371NRP1chr1033619636-ENST00000345264RSU1chr1016635495-3660774930307207
ENST00000374867NRP1chr1033619636-ENST00000377921RSU1chr1016635495-3657771927304207
ENST00000395995NRP1chr1033619636-ENST00000377921RSU1chr1016635495-313424814601837125
ENST00000374821NRP1chr1033619636-ENST00000377921RSU1chr1016635495-327438844490148
ENST00000374822NRP1chr1033619636-ENST00000377921RSU1chr1016635495-3394508164610148
ENST00000374823NRP1chr1033619636-ENST00000377921RSU1chr1016635495-313424814601837125
ENST00000374816NRP1chr1033619636-ENST00000377921RSU1chr1016635495-327438844490148
ENST00000432372NRP1chr1033619636-ENST00000602389RSU1chr1016635495-3672795951328207

check buttonDeepORF prediction of the coding potential based on the fusion transcript sequence of in-frame fusion genes. DeepORF is a coding potential classifier based on convolutional neural network by comparing the real Ribo-seq data. If the no-coding score < 0.5 and coding score > 0.5, then the in-frame fusion transcript is predicted as being likely translated.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandNo-coding scoreCoding score
ENST00000265371ENST00000345264NRP1chr1033619636-RSU1chr1016635495-0.696982260.3030178
ENST00000374867ENST00000377921NRP1chr1033619636-RSU1chr1016635495-0.70402690.29597306
ENST00000395995ENST00000377921NRP1chr1033619636-RSU1chr1016635495-0.68915870.31084132
ENST00000374821ENST00000377921NRP1chr1033619636-RSU1chr1016635495-0.69848510.30151495
ENST00000374822ENST00000377921NRP1chr1033619636-RSU1chr1016635495-0.680770750.3192292
ENST00000374823ENST00000377921NRP1chr1033619636-RSU1chr1016635495-0.68915870.31084132
ENST00000374816ENST00000377921NRP1chr1033619636-RSU1chr1016635495-0.69848510.30151495
ENST00000432372ENST00000602389NRP1chr1033619636-RSU1chr1016635495-0.614445150.38555485

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Fusion Genomic Features for NRP1-RSU1


check buttonFusionAI prediction of the potential fusion gene breakpoint based on the pre-mature RNA sequence context (+/- 5kb of individual partner genes, total 20kb length sequence). FusionAI is a fusion gene breakpoint classifier based on convolutional neural network by comparing the fusion positive and negative sequence context of ~ 20K fusion gene data. From here, we can have the relative potentency of the 20K genomic sequence how individual sequnce will be likely used as the gene fusion breakpoints.
HgeneHchrHbpHstrandTgeneTchrTbpTstrand1-pp (fusion gene breakpoint)

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions. We integrated a total of 44 different types of human genomic feature loci information across five big categories including virus integration sites, repeats, structural variants, chromatin states, and gene expression regulation. More details are in help page.
genomic feature

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions that are ovelapped with the top 1% feature importance score regions. More details are in help page.

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Fusion Protein Features for NRP1-RSU1


check button Four levels of functional features of fusion genes
Go to FGviewer search page for the most frequent breakpoint (https://ccsmweb.uth.edu/FGviewer/chr10:33619636/chr10:16635495)
- FGviewer provides the online visualization of the retention search of the protein functional features across DNA, RNA, protein, and pathological levels.
- How to search
1. Put your fusion gene symbol.
2. Press the tab key until there will be shown the breakpoint information filled.
4. Go down and press 'Search' tab twice.
4. Go down to have the hyperlink of the search result.
5. Click the hyperlink.
6. See the FGviewer result for your fusion gene.
FGviewer

check buttonMain function of each fusion partner protein. (from UniProt)
HgeneTgene
NRP1

O14786

.
FUNCTION: Cell-surface receptor involved in the development of the cardiovascular system, in angiogenesis, in the formation of certain neuronal circuits and in organogenesis outside the nervous system. Mediates the chemorepulsant activity of semaphorins (PubMed:9288753, PubMed:9529250, PubMed:10688880). Recognizes a C-end rule (CendR) motif R/KXXR/K on its ligands which causes cellular internalization and vascular leakage (PubMed:19805273). It binds to semaphorin 3A, the PLGF-2 isoform of PGF, the VEGF165 isoform of VEGFA and VEGFB (PubMed:9288753, PubMed:9529250, PubMed:10688880, PubMed:19805273). Coexpression with KDR results in increased VEGF165 binding to KDR as well as increased chemotaxis. Regulates VEGF-induced angiogenesis. Binding to VEGFA initiates a signaling pathway needed for motor neuron axon guidance and cell body migration, including for the caudal migration of facial motor neurons from rhombomere 4 to rhombomere 6 during embryonic development (By similarity). Regulates mitochondrial iron transport via interaction with ABCB8/MITOSUR (PubMed:30623799). {ECO:0000250|UniProtKB:P97333, ECO:0000269|PubMed:10688880, ECO:0000269|PubMed:19805273, ECO:0000269|PubMed:30623799, ECO:0000269|PubMed:9288753, ECO:0000269|PubMed:9529250}.; FUNCTION: [Isoform 2]: Binds VEGF-165 and may inhibit its binding to cells (PubMed:10748121, PubMed:26503042). May induce apoptosis by sequestering VEGF-165 (PubMed:10748121). May bind as well various members of the semaphorin family. Its expression has an averse effect on blood vessel number and integrity. {ECO:0000269|PubMed:10748121, ECO:0000269|PubMed:26503042}.; FUNCTION: (Microbial infection) Acts as a host factor for human coronavirus SARS-CoV-2 infection. Recognizes and binds to CendR motif RRAR on SARS-CoV-2 spike protein S1 which enhances SARS-CoV-2 infection. {ECO:0000269|PubMed:33082293, ECO:0000269|PubMed:33082294}.FUNCTION: Transcriptional activator which is required for calcium-dependent dendritic growth and branching in cortical neurons. Recruits CREB-binding protein (CREBBP) to nuclear bodies. Component of the CREST-BRG1 complex, a multiprotein complex that regulates promoter activation by orchestrating a calcium-dependent release of a repressor complex and a recruitment of an activator complex. In resting neurons, transcription of the c-FOS promoter is inhibited by BRG1-dependent recruitment of a phospho-RB1-HDAC1 repressor complex. Upon calcium influx, RB1 is dephosphorylated by calcineurin, which leads to release of the repressor complex. At the same time, there is increased recruitment of CREBBP to the promoter by a CREST-dependent mechanism, which leads to transcriptional activation. The CREST-BRG1 complex also binds to the NR2B promoter, and activity-dependent induction of NR2B expression involves a release of HDAC1 and recruitment of CREBBP (By similarity). {ECO:0000250}.

check buttonRetention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at

download page


* Minus value of BPloci means that the break pointn is located before the CDS.
- In-frame and retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note

- In-frame and not-retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneNRP1chr10:33619636chr10:16635495ENST00000265371-318147_26582924.0DomainCUB 2
HgeneNRP1chr10:33619636chr10:16635495ENST00000265371-31827_14182924.0DomainCUB 1
HgeneNRP1chr10:33619636chr10:16635495ENST00000265371-318645_81182924.0DomainMAM
HgeneNRP1chr10:33619636chr10:16635495ENST00000374821-211147_26582610.0DomainCUB 2
HgeneNRP1chr10:33619636chr10:16635495ENST00000374821-21127_14182610.0DomainCUB 1
HgeneNRP1chr10:33619636chr10:16635495ENST00000374821-211645_81182610.0DomainMAM
HgeneNRP1chr10:33619636chr10:16635495ENST00000374822-212147_26582645.0DomainCUB 2
HgeneNRP1chr10:33619636chr10:16635495ENST00000374822-21227_14182645.0DomainCUB 1
HgeneNRP1chr10:33619636chr10:16635495ENST00000374822-212645_81182645.0DomainMAM
HgeneNRP1chr10:33619636chr10:16635495ENST00000374867-217147_26582924.0DomainCUB 2
HgeneNRP1chr10:33619636chr10:16635495ENST00000374867-21727_14182924.0DomainCUB 1
HgeneNRP1chr10:33619636chr10:16635495ENST00000374867-217645_81182924.0DomainMAM
HgeneNRP1chr10:33619636chr10:16635495ENST00000265371-31822_85682924.0Topological domainExtracellular
HgeneNRP1chr10:33619636chr10:16635495ENST00000265371-318880_92382924.0Topological domainCytoplasmic
HgeneNRP1chr10:33619636chr10:16635495ENST00000374821-21122_85682610.0Topological domainExtracellular
HgeneNRP1chr10:33619636chr10:16635495ENST00000374821-211880_92382610.0Topological domainCytoplasmic
HgeneNRP1chr10:33619636chr10:16635495ENST00000374822-21222_85682645.0Topological domainExtracellular
HgeneNRP1chr10:33619636chr10:16635495ENST00000374822-212880_92382645.0Topological domainCytoplasmic
HgeneNRP1chr10:33619636chr10:16635495ENST00000374867-21722_85682924.0Topological domainExtracellular
HgeneNRP1chr10:33619636chr10:16635495ENST00000374867-217880_92382924.0Topological domainCytoplasmic
HgeneNRP1chr10:33619636chr10:16635495ENST00000265371-318857_87982924.0TransmembraneHelical
HgeneNRP1chr10:33619636chr10:16635495ENST00000374821-211857_87982610.0TransmembraneHelical
HgeneNRP1chr10:33619636chr10:16635495ENST00000374822-212857_87982645.0TransmembraneHelical
HgeneNRP1chr10:33619636chr10:16635495ENST00000374867-217857_87982924.0TransmembraneHelical
TgeneRSU1chr10:33619636chr10:16635495ENST0000034526479110_133243278.0RepeatNote=LRR 4
TgeneRSU1chr10:33619636chr10:16635495ENST0000034526479135_156243278.0RepeatNote=LRR 5
TgeneRSU1chr10:33619636chr10:16635495ENST0000034526479158_179243278.0RepeatNote=LRR 6
TgeneRSU1chr10:33619636chr10:16635495ENST0000034526479181_202243278.0RepeatNote=LRR 7
TgeneRSU1chr10:33619636chr10:16635495ENST000003452647941_63243278.0RepeatNote=LRR 1
TgeneRSU1chr10:33619636chr10:16635495ENST000003452647964_85243278.0RepeatNote=LRR 2
TgeneRSU1chr10:33619636chr10:16635495ENST000003452647987_109243278.0RepeatNote=LRR 3
TgeneRSU1chr10:33619636chr10:16635495ENST0000037792168110_133243278.0RepeatNote=LRR 4
TgeneRSU1chr10:33619636chr10:16635495ENST0000037792168135_156243278.0RepeatNote=LRR 5
TgeneRSU1chr10:33619636chr10:16635495ENST0000037792168158_179243278.0RepeatNote=LRR 6
TgeneRSU1chr10:33619636chr10:16635495ENST0000037792168181_202243278.0RepeatNote=LRR 7
TgeneRSU1chr10:33619636chr10:16635495ENST000003779216841_63243278.0RepeatNote=LRR 1
TgeneRSU1chr10:33619636chr10:16635495ENST000003779216864_85243278.0RepeatNote=LRR 2
TgeneRSU1chr10:33619636chr10:16635495ENST000003779216887_109243278.0RepeatNote=LRR 3
TgeneRSU1chr10:33619636chr10:16635495ENST0000060238968110_133190225.0RepeatNote=LRR 4
TgeneRSU1chr10:33619636chr10:16635495ENST0000060238968135_156190225.0RepeatNote=LRR 5
TgeneRSU1chr10:33619636chr10:16635495ENST0000060238968158_179190225.0RepeatNote=LRR 6
TgeneRSU1chr10:33619636chr10:16635495ENST0000060238968181_202190225.0RepeatNote=LRR 7
TgeneRSU1chr10:33619636chr10:16635495ENST000006023896841_63190225.0RepeatNote=LRR 1
TgeneRSU1chr10:33619636chr10:16635495ENST000006023896864_85190225.0RepeatNote=LRR 2
TgeneRSU1chr10:33619636chr10:16635495ENST000006023896887_109190225.0RepeatNote=LRR 3


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Fusion Gene Sequence for NRP1-RSU1


check button For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. To have fusion amino acid sequence, we ran ORFfinder and chose the longest ORF among the all predicted ones.
>60346_60346_1_NRP1-RSU1_NRP1_chr10_33619636_ENST00000265371_RSU1_chr10_16635495_ENST00000345264_length(transcript)=3660nt_BP=774nt
GCCAAAACCTTTGACCAGAGTCTCCTTGCCAGCATTCCTACCTCCCTTTGGCCAGCTATTTGTGCCAGACACCCGGACCTCCCCTGGGCG
CCAGCTCCGCGGCTCCAACGGGTCCAGAAACAAGCCGGATTTTTTTTTTTTCTTCCTGGAAATTGGCTTTGGTGTGTGTTGCCCTACCTC
CCTCCTCCCCCTCCCACCCACAGCCCCCCCCCGGCCTTTTTTTTTTTTTTTTTTTTTTTTGAGACATGGCCCGGGCAGTGGCTCCTGGAA
GAGGAACAAGTGTGGGAAAAGGGAGAGGAAGCCGGAGCTAAATGACAGGATGCAGGCGACTTGAGACACAAAAAGAGAAGCGTTCCTCTC
GGATCCAGGCATTGCCTCGCTGCTTTCTTTTCTCCAAGACGGGCTGAGGATTGTACAGCTCTAGGCGGAGTTGGGGCTCTTCGGATCGCT
TAGATTCTCCTCTTTGCTGCATTTCCCCCCACGTCCTCGTTCTCCCGCGTCTGCCTGCGGACCCGGAGAAGGGAGAATGGAGAGGGGGCT
GCCGCTCCTCTGCGCCGTGCTCGCCCTCGTCCTCGCCCCGGCCGGCGCTTTTCGCAACGATAAATGTGGCGATACTATAAAAATTGAAAG
CCCCGGGTACCTTACATCTCCTGGTTATCCTCATTCTTATCACCCAAGTGAAAAATGCGAATGGCTGATTCAGGCTCCGGACCCATACCA
GAGAATTATGATCAACTTCAACCCTCACTTCGATTTGGAGGACAGAGACTGCAACCTCTACGGCAGACACATGCAGGCCAACCCAGAACC
ACCGAAGAAGAATAATGACAAATCGAAAAAGATCAGCCGGAAACCCCTGGCAGCCAAGAACAGATAAGGAAGGGATTGGCATCGGCTGGC
CTTCCAGCACCTTCTCTCTCCAACACTTCATTCTCTCTTGCCCTGTCTCTCAAATAAACCCAATGCTGCGTGTGAGGCCTTTTTTATTTT
TCTTTTCACTCTCTTTCTAATGCTTCCCACCTTACCTTTTAGATTCTTTTGCTAGGTGGGAGATTGTTATAAGGTCTTTAAACCATTTCC
ATTTGTTTCTTTAACATTACCAAAAGCAGGGAACAAAGCTCTTATTCAACTGCGAATTCCATAGTGGGCTCTGGCTTTTCTTGAATAGAT
ATCACAAGGTTGCTTATTATCAAAAGAATAATTAAAATCATGTAACCATTTAAATGTCACTGTTAACACTTTTCACTCTTTCTGTTGATT
CACCTAACTCATTATTTTGCTTTATTAAAAGTCTTCCTTCACCACCGAGATATGCTAATTTAACTTACAAATGATTTTAATAAAATCTTG
AGTTTGTATCACATGTTACTTATTGACTCAGAATAAAAGAACAGTCTGATCTTGGGGTATAACACATTTTCATTTACTTTTCTCCCCCAA
AATCATCTTATCCAATTTTATTGGTTATACATGATAAACTTTTCATGAAAGAAATGCAAAATTAAATCACAGTTCGTTTCTTCTCACATT
AATTTGTCAAGTTTTTTTTTTCTTTGAAGACTTTCTAAATTAGGAAGCAGAAAAACAAATCTCTAGGAGATTCTGCCAAAGGATTTTGGA
AAGTAGCATTCCTTCGCCGAAGAAATGGTGATTTCTGCCAGGGGCTGGTAGACAAGAACTGTGAAAGAGAGAGAGAAAAAACCTCAACTG
TGTATTTTGTCACGGCGGAAAATCTGCTCGCATCGAAGCATTCTTCTAAGCGACTTCGATGCCAAGGAAGTTGTGTAAATGTGCACGCGC
TACACCACACCCAGGGTGGAAACCACAGTTGCAGAGTCATTAAACAATCAATTGTTTGTTTAACATCTGTGATAGGCAGCTTTCCTTCTT
TTCAACAGTGATACCTACGAAAATCAAAATAAATGCAAGCTGAGGTTTTGTGCTCACTGAAAGGGCTGTCAACCCCAGAAGGCCGACACA
AAAAAAATGGTATGTGAAGATGCACCGTCTTTTCAAATGGCCTGGGAGAGTCAAATGGCCTGGGAGAGGGGGCCTGCCCTTCTCTGCTGT
GTCCTTTCGGCTTCCCAGTTGAGCTCCCAAGACCAGGACCCACTGGGGCATATAAAATCTCTGCTGTATCCTTTCGGCTTCCCAGTTGAG
CTCCCAAGACCAGGACCCACTGGGGCATATAAAAAAGTCAAAAATCAAAATCAAACAACAAGTTCTGAGTTACTTAGGAAACAGACTTCG
CATTTCAATCAGAGAGGCCACAGAGCAAGGTCTAAACTTCTGGCTTCTAGACAAATTCCTGATAGAACATTTAAATGTGGGAAGTGGCTT
CCCCAGGTCCCATCCCCTGTTTAGGGATAGAGTTGATATCATTTTTATAGGTGCCATGTATGCCTCTGCCTGAATTTTTTTAATTGACTT
TTGAGCTTTTGAGATTGCACGAGGGAGAACAAGGCCTTTGCTGTTGTGGATAGGAAAGACTTAACCTAAAATTAAACCAGCAAGAAAGCA
TTAGTAAAAATCTAACAATATGAAGGGCTCTTATGAGTCATTTTTTTCAAAAGATGAAAACTCCAGAAACGCACAGGAACGAAATACCTC
CCAGAAACATGAAGCAATCATCGAAGACTCACTGGTAATATTTTTAAAAAGTATACAGATCAAAGCAAAAAGAAGCCATGTGTAACAAAG
AGAAATGTGCAAATATTTTTTAAGGCAGTATTAAGTGCAAGAGGAGTAACATGAAATAAACATTCTTTCACATGGCTACTGGGAATATAA
ATTTCGCTCCAGAAAGGCCGTAGCAGTTTGACGATAGGTGGCAAAACCTTAAGATTGTGTACTGGGGCCCAGAATTTTTATTTCTAGGAA
TGTATCCTGAGGAAATTATCCGAGATCCCCACAAACTGCAATGTTTAGGAATTGTCCTTATAGCATTGCATACACAAGAAAAACAGAGAA
AAGCCTGATCCCTGTCAGTGGAAAAGGGGTTCAATGAATTACGGTGTGTCTGCATGAGGCTTTTATGACATTAAAAATTGTTGAACAACG
GCCAGGCACAGTGGCTCATGCCTGTAATCCTAACACTTTGGGAGGCCAAGGTGGGAAGATTGCCTGAGCTCAGGAGTTTGAGACCAGCCT
GGGCAACACGGTGAAACCCCGTCTCTACTAAAATACAAAAAATTAGCCGGGCGTCGCAGCATGCGCCTGTAGTCCCAGCTGCTCAGGAGG
CTGAGGCAGGAGAATTGATTGAACCCGGGAGGCAGAGGTTGCACTGAGCTGAGATTAAGCCACCGCACTCCAGCCTGGGCGACAGAGCAA
GATTCCGTTCCCAAGAAAAAAAAATTGTTCAACAATAAGGGCAAAGGGAGAGAATCATAACATCTGATTAAACAGAAAAAGCAAGATTTT
TAAAACTAACTATATAAGGATGGTCCCAGCTGTGTCAAAAGGAAGCTTGTTTGTAATACGTGTGCATAAAAATTAAATAGAGGTGAACAC
AATTATTTTAAGGCAGTTAAATTATCTCTGTATTGTGAACTAAGACTTTCTAGAATTTTACTTATTCATTCTGTACTTAAATTTTTTCTA

>60346_60346_1_NRP1-RSU1_NRP1_chr10_33619636_ENST00000265371_RSU1_chr10_16635495_ENST00000345264_length(amino acids)=207AA_BP=0
MKCWREKVLEGQPMPIPSLSVLGCQGFPADLFRFVIILLRWFWVGLHVSAVEVAVSVLQIEVRVEVDHNSLVWVRSLNQPFAFFTWVIRM
RITRRCKVPGAFNFYSIATFIVAKSAGRGEDEGEHGAEERQPPLHSPFSGSAGRRGRTRTWGEMQQRGESKRSEEPQLRLELYNPQPVLE

--------------------------------------------------------------
>60346_60346_2_NRP1-RSU1_NRP1_chr10_33619636_ENST00000374816_RSU1_chr10_16635495_ENST00000377921_length(transcript)=3274nt_BP=388nt
CTTTTCTCCAAGACGGGCTGAGGATTGTACAGCTCTAGGCGGAGTTGGGGCTCTTCGGATCGCTTAGATTCTCCTCTTTGCTGCATTTCC
CCCCACGTCCTCGTTCTCCCGCGTCTGCCTGCGGACCCGGAGAAGGGAGAATGGAGAGGGGGCTGCCGCTCCTCTGCGCCGTGCTCGCCC
TCGTCCTCGCCCCGGCCGGCGCTTTTCGCAACGATAAATGTGGCGATACTATAAAAATTGAAAGCCCCGGGTACCTTACATCTCCTGGTT
ATCCTCATTCTTATCACCCAAGTGAAAAATGCGAATGGCTGATTCAGGCTCCGGACCCATACCAGAGAATTATGATCAACTTCAACCCTC
ACTTCGATTTGGAGGACAGAGACTGCAACCTCTACGGCAGACACATGCAGGCCAACCCAGAACCACCGAAGAAGAATAATGACAAATCGA
AAAAGATCAGCCGGAAACCCCTGGCAGCCAAGAACAGATAAGGAAGGGATTGGCATCGGCTGGCCTTCCAGCACCTTCTCTCTCCAACAC
TTCATTCTCTCTTGCCCTGTCTCTCAAATAAACCCAATGCTGCGTGTGAGGCCTTTTTTATTTTTCTTTTCACTCTCTTTCTAATGCTTC
CCACCTTACCTTTTAGATTCTTTTGCTAGGTGGGAGATTGTTATAAGGTCTTTAAACCATTTCCATTTGTTTCTTTAACATTACCAAAAG
CAGGGAACAAAGCTCTTATTCAACTGCGAATTCCATAGTGGGCTCTGGCTTTTCTTGAATAGATATCACAAGGTTGCTTATTATCAAAAG
AATAATTAAAATCATGTAACCATTTAAATGTCACTGTTAACACTTTTCACTCTTTCTGTTGATTCACCTAACTCATTATTTTGCTTTATT
AAAAGTCTTCCTTCACCACCGAGATATGCTAATTTAACTTACAAATGATTTTAATAAAATCTTGAGTTTGTATCACATGTTACTTATTGA
CTCAGAATAAAAGAACAGTCTGATCTTGGGGTATAACACATTTTCATTTACTTTTCTCCCCCAAAATCATCTTATCCAATTTTATTGGTT
ATACATGATAAACTTTTCATGAAAGAAATGCAAAATTAAATCACAGTTCGTTTCTTCTCACATTAATTTGTCAAGTTTTTTTTTTCTTTG
AAGACTTTCTAAATTAGGAAGCAGAAAAACAAATCTCTAGGAGATTCTGCCAAAGGATTTTGGAAAGTAGCATTCCTTCGCCGAAGAAAT
GGTGATTTCTGCCAGGGGCTGGTAGACAAGAACTGTGAAAGAGAGAGAGAAAAAACCTCAACTGTGTATTTTGTCACGGCGGAAAATCTG
CTCGCATCGAAGCATTCTTCTAAGCGACTTCGATGCCAAGGAAGTTGTGTAAATGTGCACGCGCTACACCACACCCAGGGTGGAAACCAC
AGTTGCAGAGTCATTAAACAATCAATTGTTTGTTTAACATCTGTGATAGGCAGCTTTCCTTCTTTTCAACAGTGATACCTACGAAAATCA
AAATAAATGCAAGCTGAGGTTTTGTGCTCACTGAAAGGGCTGTCAACCCCAGAAGGCCGACACAAAAAAAATGGTATGTGAAGATGCACC
GTCTTTTCAAATGGCCTGGGAGAGTCAAATGGCCTGGGAGAGGGGGCCTGCCCTTCTCTGCTGTGTCCTTTCGGCTTCCCAGTTGAGCTC
CCAAGACCAGGACCCACTGGGGCATATAAAATCTCTGCTGTATCCTTTCGGCTTCCCAGTTGAGCTCCCAAGACCAGGACCCACTGGGGC
ATATAAAAAAGTCAAAAATCAAAATCAAACAACAAGTTCTGAGTTACTTAGGAAACAGACTTCGCATTTCAATCAGAGAGGCCACAGAGC
AAGGTCTAAACTTCTGGCTTCTAGACAAATTCCTGATAGAACATTTAAATGTGGGAAGTGGCTTCCCCAGGTCCCATCCCCTGTTTAGGG
ATAGAGTTGATATCATTTTTATAGGTGCCATGTATGCCTCTGCCTGAATTTTTTTAATTGACTTTTGAGCTTTTGAGATTGCACGAGGGA
GAACAAGGCCTTTGCTGTTGTGGATAGGAAAGACTTAACCTAAAATTAAACCAGCAAGAAAGCATTAGTAAAAATCTAACAATATGAAGG
GCTCTTATGAGTCATTTTTTTCAAAAGATGAAAACTCCAGAAACGCACAGGAACGAAATACCTCCCAGAAACATGAAGCAATCATCGAAG
ACTCACTGGTAATATTTTTAAAAAGTATACAGATCAAAGCAAAAAGAAGCCATGTGTAACAAAGAGAAATGTGCAAATATTTTTTAAGGC
AGTATTAAGTGCAAGAGGAGTAACATGAAATAAACATTCTTTCACATGGCTACTGGGAATATAAATTTCGCTCCAGAAAGGCCGTAGCAG
TTTGACGATAGGTGGCAAAACCTTAAGATTGTGTACTGGGGCCCAGAATTTTTATTTCTAGGAATGTATCCTGAGGAAATTATCCGAGAT
CCCCACAAACTGCAATGTTTAGGAATTGTCCTTATAGCATTGCATACACAAGAAAAACAGAGAAAAGCCTGATCCCTGTCAGTGGAAAAG
GGGTTCAATGAATTACGGTGTGTCTGCATGAGGCTTTTATGACATTAAAAATTGTTGAACAACGGCCAGGCACAGTGGCTCATGCCTGTA
ATCCTAACACTTTGGGAGGCCAAGGTGGGAAGATTGCCTGAGCTCAGGAGTTTGAGACCAGCCTGGGCAACACGGTGAAACCCCGTCTCT
ACTAAAATACAAAAAATTAGCCGGGCGTCGCAGCATGCGCCTGTAGTCCCAGCTGCTCAGGAGGCTGAGGCAGGAGAATTGATTGAACCC
GGGAGGCAGAGGTTGCACTGAGCTGAGATTAAGCCACCGCACTCCAGCCTGGGCGACAGAGCAAGATTCCGTTCCCAAGAAAAAAAAATT
GTTCAACAATAAGGGCAAAGGGAGAGAATCATAACATCTGATTAAACAGAAAAAGCAAGATTTTTAAAACTAACTATATAAGGATGGTCC
CAGCTGTGTCAAAAGGAAGCTTGTTTGTAATACGTGTGCATAAAAATTAAATAGAGGTGAACACAATTATTTTAAGGCAGTTAAATTATC
TCTGTATTGTGAACTAAGACTTTCTAGAATTTTACTTATTCATTCTGTACTTAAATTTTTTCTAATGAACACATATACTTTTGTAATCAG

>60346_60346_2_NRP1-RSU1_NRP1_chr10_33619636_ENST00000374816_RSU1_chr10_16635495_ENST00000377921_length(amino acids)=148AA_BP=70
MGLFGSLRFSSLLHFPPRPRSPASACGPGEGRMERGLPLLCAVLALVLAPAGAFRNDKCGDTIKIESPGYLTSPGYPHSYHPSEKCEWLI

--------------------------------------------------------------
>60346_60346_3_NRP1-RSU1_NRP1_chr10_33619636_ENST00000374821_RSU1_chr10_16635495_ENST00000377921_length(transcript)=3274nt_BP=388nt
CTTTTCTCCAAGACGGGCTGAGGATTGTACAGCTCTAGGCGGAGTTGGGGCTCTTCGGATCGCTTAGATTCTCCTCTTTGCTGCATTTCC
CCCCACGTCCTCGTTCTCCCGCGTCTGCCTGCGGACCCGGAGAAGGGAGAATGGAGAGGGGGCTGCCGCTCCTCTGCGCCGTGCTCGCCC
TCGTCCTCGCCCCGGCCGGCGCTTTTCGCAACGATAAATGTGGCGATACTATAAAAATTGAAAGCCCCGGGTACCTTACATCTCCTGGTT
ATCCTCATTCTTATCACCCAAGTGAAAAATGCGAATGGCTGATTCAGGCTCCGGACCCATACCAGAGAATTATGATCAACTTCAACCCTC
ACTTCGATTTGGAGGACAGAGACTGCAACCTCTACGGCAGACACATGCAGGCCAACCCAGAACCACCGAAGAAGAATAATGACAAATCGA
AAAAGATCAGCCGGAAACCCCTGGCAGCCAAGAACAGATAAGGAAGGGATTGGCATCGGCTGGCCTTCCAGCACCTTCTCTCTCCAACAC
TTCATTCTCTCTTGCCCTGTCTCTCAAATAAACCCAATGCTGCGTGTGAGGCCTTTTTTATTTTTCTTTTCACTCTCTTTCTAATGCTTC
CCACCTTACCTTTTAGATTCTTTTGCTAGGTGGGAGATTGTTATAAGGTCTTTAAACCATTTCCATTTGTTTCTTTAACATTACCAAAAG
CAGGGAACAAAGCTCTTATTCAACTGCGAATTCCATAGTGGGCTCTGGCTTTTCTTGAATAGATATCACAAGGTTGCTTATTATCAAAAG
AATAATTAAAATCATGTAACCATTTAAATGTCACTGTTAACACTTTTCACTCTTTCTGTTGATTCACCTAACTCATTATTTTGCTTTATT
AAAAGTCTTCCTTCACCACCGAGATATGCTAATTTAACTTACAAATGATTTTAATAAAATCTTGAGTTTGTATCACATGTTACTTATTGA
CTCAGAATAAAAGAACAGTCTGATCTTGGGGTATAACACATTTTCATTTACTTTTCTCCCCCAAAATCATCTTATCCAATTTTATTGGTT
ATACATGATAAACTTTTCATGAAAGAAATGCAAAATTAAATCACAGTTCGTTTCTTCTCACATTAATTTGTCAAGTTTTTTTTTTCTTTG
AAGACTTTCTAAATTAGGAAGCAGAAAAACAAATCTCTAGGAGATTCTGCCAAAGGATTTTGGAAAGTAGCATTCCTTCGCCGAAGAAAT
GGTGATTTCTGCCAGGGGCTGGTAGACAAGAACTGTGAAAGAGAGAGAGAAAAAACCTCAACTGTGTATTTTGTCACGGCGGAAAATCTG
CTCGCATCGAAGCATTCTTCTAAGCGACTTCGATGCCAAGGAAGTTGTGTAAATGTGCACGCGCTACACCACACCCAGGGTGGAAACCAC
AGTTGCAGAGTCATTAAACAATCAATTGTTTGTTTAACATCTGTGATAGGCAGCTTTCCTTCTTTTCAACAGTGATACCTACGAAAATCA
AAATAAATGCAAGCTGAGGTTTTGTGCTCACTGAAAGGGCTGTCAACCCCAGAAGGCCGACACAAAAAAAATGGTATGTGAAGATGCACC
GTCTTTTCAAATGGCCTGGGAGAGTCAAATGGCCTGGGAGAGGGGGCCTGCCCTTCTCTGCTGTGTCCTTTCGGCTTCCCAGTTGAGCTC
CCAAGACCAGGACCCACTGGGGCATATAAAATCTCTGCTGTATCCTTTCGGCTTCCCAGTTGAGCTCCCAAGACCAGGACCCACTGGGGC
ATATAAAAAAGTCAAAAATCAAAATCAAACAACAAGTTCTGAGTTACTTAGGAAACAGACTTCGCATTTCAATCAGAGAGGCCACAGAGC
AAGGTCTAAACTTCTGGCTTCTAGACAAATTCCTGATAGAACATTTAAATGTGGGAAGTGGCTTCCCCAGGTCCCATCCCCTGTTTAGGG
ATAGAGTTGATATCATTTTTATAGGTGCCATGTATGCCTCTGCCTGAATTTTTTTAATTGACTTTTGAGCTTTTGAGATTGCACGAGGGA
GAACAAGGCCTTTGCTGTTGTGGATAGGAAAGACTTAACCTAAAATTAAACCAGCAAGAAAGCATTAGTAAAAATCTAACAATATGAAGG
GCTCTTATGAGTCATTTTTTTCAAAAGATGAAAACTCCAGAAACGCACAGGAACGAAATACCTCCCAGAAACATGAAGCAATCATCGAAG
ACTCACTGGTAATATTTTTAAAAAGTATACAGATCAAAGCAAAAAGAAGCCATGTGTAACAAAGAGAAATGTGCAAATATTTTTTAAGGC
AGTATTAAGTGCAAGAGGAGTAACATGAAATAAACATTCTTTCACATGGCTACTGGGAATATAAATTTCGCTCCAGAAAGGCCGTAGCAG
TTTGACGATAGGTGGCAAAACCTTAAGATTGTGTACTGGGGCCCAGAATTTTTATTTCTAGGAATGTATCCTGAGGAAATTATCCGAGAT
CCCCACAAACTGCAATGTTTAGGAATTGTCCTTATAGCATTGCATACACAAGAAAAACAGAGAAAAGCCTGATCCCTGTCAGTGGAAAAG
GGGTTCAATGAATTACGGTGTGTCTGCATGAGGCTTTTATGACATTAAAAATTGTTGAACAACGGCCAGGCACAGTGGCTCATGCCTGTA
ATCCTAACACTTTGGGAGGCCAAGGTGGGAAGATTGCCTGAGCTCAGGAGTTTGAGACCAGCCTGGGCAACACGGTGAAACCCCGTCTCT
ACTAAAATACAAAAAATTAGCCGGGCGTCGCAGCATGCGCCTGTAGTCCCAGCTGCTCAGGAGGCTGAGGCAGGAGAATTGATTGAACCC
GGGAGGCAGAGGTTGCACTGAGCTGAGATTAAGCCACCGCACTCCAGCCTGGGCGACAGAGCAAGATTCCGTTCCCAAGAAAAAAAAATT
GTTCAACAATAAGGGCAAAGGGAGAGAATCATAACATCTGATTAAACAGAAAAAGCAAGATTTTTAAAACTAACTATATAAGGATGGTCC
CAGCTGTGTCAAAAGGAAGCTTGTTTGTAATACGTGTGCATAAAAATTAAATAGAGGTGAACACAATTATTTTAAGGCAGTTAAATTATC
TCTGTATTGTGAACTAAGACTTTCTAGAATTTTACTTATTCATTCTGTACTTAAATTTTTTCTAATGAACACATATACTTTTGTAATCAG

>60346_60346_3_NRP1-RSU1_NRP1_chr10_33619636_ENST00000374821_RSU1_chr10_16635495_ENST00000377921_length(amino acids)=148AA_BP=70
MGLFGSLRFSSLLHFPPRPRSPASACGPGEGRMERGLPLLCAVLALVLAPAGAFRNDKCGDTIKIESPGYLTSPGYPHSYHPSEKCEWLI

--------------------------------------------------------------
>60346_60346_4_NRP1-RSU1_NRP1_chr10_33619636_ENST00000374822_RSU1_chr10_16635495_ENST00000377921_length(transcript)=3394nt_BP=508nt
GGAAGAGGAACAAGTGTGGGAAAAGGGAGAGGAAGCCGGAGCTAAATGACAGGATGCAGGCGACTTGAGACACAAAAAGAGAAGCGTTCC
TCTCGGATCCAGGCATTGCCTCGCTGCTTTCTTTTCTCCAAGACGGGCTGAGGATTGTACAGCTCTAGGCGGAGTTGGGGCTCTTCGGAT
CGCTTAGATTCTCCTCTTTGCTGCATTTCCCCCCACGTCCTCGTTCTCCCGCGTCTGCCTGCGGACCCGGAGAAGGGAGAATGGAGAGGG
GGCTGCCGCTCCTCTGCGCCGTGCTCGCCCTCGTCCTCGCCCCGGCCGGCGCTTTTCGCAACGATAAATGTGGCGATACTATAAAAATTG
AAAGCCCCGGGTACCTTACATCTCCTGGTTATCCTCATTCTTATCACCCAAGTGAAAAATGCGAATGGCTGATTCAGGCTCCGGACCCAT
ACCAGAGAATTATGATCAACTTCAACCCTCACTTCGATTTGGAGGACAGAGACTGCAACCTCTACGGCAGACACATGCAGGCCAACCCAG
AACCACCGAAGAAGAATAATGACAAATCGAAAAAGATCAGCCGGAAACCCCTGGCAGCCAAGAACAGATAAGGAAGGGATTGGCATCGGC
TGGCCTTCCAGCACCTTCTCTCTCCAACACTTCATTCTCTCTTGCCCTGTCTCTCAAATAAACCCAATGCTGCGTGTGAGGCCTTTTTTA
TTTTTCTTTTCACTCTCTTTCTAATGCTTCCCACCTTACCTTTTAGATTCTTTTGCTAGGTGGGAGATTGTTATAAGGTCTTTAAACCAT
TTCCATTTGTTTCTTTAACATTACCAAAAGCAGGGAACAAAGCTCTTATTCAACTGCGAATTCCATAGTGGGCTCTGGCTTTTCTTGAAT
AGATATCACAAGGTTGCTTATTATCAAAAGAATAATTAAAATCATGTAACCATTTAAATGTCACTGTTAACACTTTTCACTCTTTCTGTT
GATTCACCTAACTCATTATTTTGCTTTATTAAAAGTCTTCCTTCACCACCGAGATATGCTAATTTAACTTACAAATGATTTTAATAAAAT
CTTGAGTTTGTATCACATGTTACTTATTGACTCAGAATAAAAGAACAGTCTGATCTTGGGGTATAACACATTTTCATTTACTTTTCTCCC
CCAAAATCATCTTATCCAATTTTATTGGTTATACATGATAAACTTTTCATGAAAGAAATGCAAAATTAAATCACAGTTCGTTTCTTCTCA
CATTAATTTGTCAAGTTTTTTTTTTCTTTGAAGACTTTCTAAATTAGGAAGCAGAAAAACAAATCTCTAGGAGATTCTGCCAAAGGATTT
TGGAAAGTAGCATTCCTTCGCCGAAGAAATGGTGATTTCTGCCAGGGGCTGGTAGACAAGAACTGTGAAAGAGAGAGAGAAAAAACCTCA
ACTGTGTATTTTGTCACGGCGGAAAATCTGCTCGCATCGAAGCATTCTTCTAAGCGACTTCGATGCCAAGGAAGTTGTGTAAATGTGCAC
GCGCTACACCACACCCAGGGTGGAAACCACAGTTGCAGAGTCATTAAACAATCAATTGTTTGTTTAACATCTGTGATAGGCAGCTTTCCT
TCTTTTCAACAGTGATACCTACGAAAATCAAAATAAATGCAAGCTGAGGTTTTGTGCTCACTGAAAGGGCTGTCAACCCCAGAAGGCCGA
CACAAAAAAAATGGTATGTGAAGATGCACCGTCTTTTCAAATGGCCTGGGAGAGTCAAATGGCCTGGGAGAGGGGGCCTGCCCTTCTCTG
CTGTGTCCTTTCGGCTTCCCAGTTGAGCTCCCAAGACCAGGACCCACTGGGGCATATAAAATCTCTGCTGTATCCTTTCGGCTTCCCAGT
TGAGCTCCCAAGACCAGGACCCACTGGGGCATATAAAAAAGTCAAAAATCAAAATCAAACAACAAGTTCTGAGTTACTTAGGAAACAGAC
TTCGCATTTCAATCAGAGAGGCCACAGAGCAAGGTCTAAACTTCTGGCTTCTAGACAAATTCCTGATAGAACATTTAAATGTGGGAAGTG
GCTTCCCCAGGTCCCATCCCCTGTTTAGGGATAGAGTTGATATCATTTTTATAGGTGCCATGTATGCCTCTGCCTGAATTTTTTTAATTG
ACTTTTGAGCTTTTGAGATTGCACGAGGGAGAACAAGGCCTTTGCTGTTGTGGATAGGAAAGACTTAACCTAAAATTAAACCAGCAAGAA
AGCATTAGTAAAAATCTAACAATATGAAGGGCTCTTATGAGTCATTTTTTTCAAAAGATGAAAACTCCAGAAACGCACAGGAACGAAATA
CCTCCCAGAAACATGAAGCAATCATCGAAGACTCACTGGTAATATTTTTAAAAAGTATACAGATCAAAGCAAAAAGAAGCCATGTGTAAC
AAAGAGAAATGTGCAAATATTTTTTAAGGCAGTATTAAGTGCAAGAGGAGTAACATGAAATAAACATTCTTTCACATGGCTACTGGGAAT
ATAAATTTCGCTCCAGAAAGGCCGTAGCAGTTTGACGATAGGTGGCAAAACCTTAAGATTGTGTACTGGGGCCCAGAATTTTTATTTCTA
GGAATGTATCCTGAGGAAATTATCCGAGATCCCCACAAACTGCAATGTTTAGGAATTGTCCTTATAGCATTGCATACACAAGAAAAACAG
AGAAAAGCCTGATCCCTGTCAGTGGAAAAGGGGTTCAATGAATTACGGTGTGTCTGCATGAGGCTTTTATGACATTAAAAATTGTTGAAC
AACGGCCAGGCACAGTGGCTCATGCCTGTAATCCTAACACTTTGGGAGGCCAAGGTGGGAAGATTGCCTGAGCTCAGGAGTTTGAGACCA
GCCTGGGCAACACGGTGAAACCCCGTCTCTACTAAAATACAAAAAATTAGCCGGGCGTCGCAGCATGCGCCTGTAGTCCCAGCTGCTCAG
GAGGCTGAGGCAGGAGAATTGATTGAACCCGGGAGGCAGAGGTTGCACTGAGCTGAGATTAAGCCACCGCACTCCAGCCTGGGCGACAGA
GCAAGATTCCGTTCCCAAGAAAAAAAAATTGTTCAACAATAAGGGCAAAGGGAGAGAATCATAACATCTGATTAAACAGAAAAAGCAAGA
TTTTTAAAACTAACTATATAAGGATGGTCCCAGCTGTGTCAAAAGGAAGCTTGTTTGTAATACGTGTGCATAAAAATTAAATAGAGGTGA
ACACAATTATTTTAAGGCAGTTAAATTATCTCTGTATTGTGAACTAAGACTTTCTAGAATTTTACTTATTCATTCTGTACTTAAATTTTT

>60346_60346_4_NRP1-RSU1_NRP1_chr10_33619636_ENST00000374822_RSU1_chr10_16635495_ENST00000377921_length(amino acids)=148AA_BP=70
MGLFGSLRFSSLLHFPPRPRSPASACGPGEGRMERGLPLLCAVLALVLAPAGAFRNDKCGDTIKIESPGYLTSPGYPHSYHPSEKCEWLI

--------------------------------------------------------------
>60346_60346_5_NRP1-RSU1_NRP1_chr10_33619636_ENST00000374823_RSU1_chr10_16635495_ENST00000377921_length(transcript)=3134nt_BP=248nt
ATGGAGAGGGGGCTGCCGCTCCTCTGCGCCGTGCTCGCCCTCGTCCTCGCCCCGGCCGGCGCTTTTCGCAACGATAAATGTGGCGATACT
ATAAAAATTGAAAGCCCCGGGTACCTTACATCTCCTGGTTATCCTCATTCTTATCACCCAAGTGAAAAATGCGAATGGCTGATTCAGGCT
CCGGACCCATACCAGAGAATTATGATCAACTTCAACCCTCACTTCGATTTGGAGGACAGAGACTGCAACCTCTACGGCAGACACATGCAG
GCCAACCCAGAACCACCGAAGAAGAATAATGACAAATCGAAAAAGATCAGCCGGAAACCCCTGGCAGCCAAGAACAGATAAGGAAGGGAT
TGGCATCGGCTGGCCTTCCAGCACCTTCTCTCTCCAACACTTCATTCTCTCTTGCCCTGTCTCTCAAATAAACCCAATGCTGCGTGTGAG
GCCTTTTTTATTTTTCTTTTCACTCTCTTTCTAATGCTTCCCACCTTACCTTTTAGATTCTTTTGCTAGGTGGGAGATTGTTATAAGGTC
TTTAAACCATTTCCATTTGTTTCTTTAACATTACCAAAAGCAGGGAACAAAGCTCTTATTCAACTGCGAATTCCATAGTGGGCTCTGGCT
TTTCTTGAATAGATATCACAAGGTTGCTTATTATCAAAAGAATAATTAAAATCATGTAACCATTTAAATGTCACTGTTAACACTTTTCAC
TCTTTCTGTTGATTCACCTAACTCATTATTTTGCTTTATTAAAAGTCTTCCTTCACCACCGAGATATGCTAATTTAACTTACAAATGATT
TTAATAAAATCTTGAGTTTGTATCACATGTTACTTATTGACTCAGAATAAAAGAACAGTCTGATCTTGGGGTATAACACATTTTCATTTA
CTTTTCTCCCCCAAAATCATCTTATCCAATTTTATTGGTTATACATGATAAACTTTTCATGAAAGAAATGCAAAATTAAATCACAGTTCG
TTTCTTCTCACATTAATTTGTCAAGTTTTTTTTTTCTTTGAAGACTTTCTAAATTAGGAAGCAGAAAAACAAATCTCTAGGAGATTCTGC
CAAAGGATTTTGGAAAGTAGCATTCCTTCGCCGAAGAAATGGTGATTTCTGCCAGGGGCTGGTAGACAAGAACTGTGAAAGAGAGAGAGA
AAAAACCTCAACTGTGTATTTTGTCACGGCGGAAAATCTGCTCGCATCGAAGCATTCTTCTAAGCGACTTCGATGCCAAGGAAGTTGTGT
AAATGTGCACGCGCTACACCACACCCAGGGTGGAAACCACAGTTGCAGAGTCATTAAACAATCAATTGTTTGTTTAACATCTGTGATAGG
CAGCTTTCCTTCTTTTCAACAGTGATACCTACGAAAATCAAAATAAATGCAAGCTGAGGTTTTGTGCTCACTGAAAGGGCTGTCAACCCC
AGAAGGCCGACACAAAAAAAATGGTATGTGAAGATGCACCGTCTTTTCAAATGGCCTGGGAGAGTCAAATGGCCTGGGAGAGGGGGCCTG
CCCTTCTCTGCTGTGTCCTTTCGGCTTCCCAGTTGAGCTCCCAAGACCAGGACCCACTGGGGCATATAAAATCTCTGCTGTATCCTTTCG
GCTTCCCAGTTGAGCTCCCAAGACCAGGACCCACTGGGGCATATAAAAAAGTCAAAAATCAAAATCAAACAACAAGTTCTGAGTTACTTA
GGAAACAGACTTCGCATTTCAATCAGAGAGGCCACAGAGCAAGGTCTAAACTTCTGGCTTCTAGACAAATTCCTGATAGAACATTTAAAT
GTGGGAAGTGGCTTCCCCAGGTCCCATCCCCTGTTTAGGGATAGAGTTGATATCATTTTTATAGGTGCCATGTATGCCTCTGCCTGAATT
TTTTTAATTGACTTTTGAGCTTTTGAGATTGCACGAGGGAGAACAAGGCCTTTGCTGTTGTGGATAGGAAAGACTTAACCTAAAATTAAA
CCAGCAAGAAAGCATTAGTAAAAATCTAACAATATGAAGGGCTCTTATGAGTCATTTTTTTCAAAAGATGAAAACTCCAGAAACGCACAG
GAACGAAATACCTCCCAGAAACATGAAGCAATCATCGAAGACTCACTGGTAATATTTTTAAAAAGTATACAGATCAAAGCAAAAAGAAGC
CATGTGTAACAAAGAGAAATGTGCAAATATTTTTTAAGGCAGTATTAAGTGCAAGAGGAGTAACATGAAATAAACATTCTTTCACATGGC
TACTGGGAATATAAATTTCGCTCCAGAAAGGCCGTAGCAGTTTGACGATAGGTGGCAAAACCTTAAGATTGTGTACTGGGGCCCAGAATT
TTTATTTCTAGGAATGTATCCTGAGGAAATTATCCGAGATCCCCACAAACTGCAATGTTTAGGAATTGTCCTTATAGCATTGCATACACA
AGAAAAACAGAGAAAAGCCTGATCCCTGTCAGTGGAAAAGGGGTTCAATGAATTACGGTGTGTCTGCATGAGGCTTTTATGACATTAAAA
ATTGTTGAACAACGGCCAGGCACAGTGGCTCATGCCTGTAATCCTAACACTTTGGGAGGCCAAGGTGGGAAGATTGCCTGAGCTCAGGAG
TTTGAGACCAGCCTGGGCAACACGGTGAAACCCCGTCTCTACTAAAATACAAAAAATTAGCCGGGCGTCGCAGCATGCGCCTGTAGTCCC
AGCTGCTCAGGAGGCTGAGGCAGGAGAATTGATTGAACCCGGGAGGCAGAGGTTGCACTGAGCTGAGATTAAGCCACCGCACTCCAGCCT
GGGCGACAGAGCAAGATTCCGTTCCCAAGAAAAAAAAATTGTTCAACAATAAGGGCAAAGGGAGAGAATCATAACATCTGATTAAACAGA
AAAAGCAAGATTTTTAAAACTAACTATATAAGGATGGTCCCAGCTGTGTCAAAAGGAAGCTTGTTTGTAATACGTGTGCATAAAAATTAA
ATAGAGGTGAACACAATTATTTTAAGGCAGTTAAATTATCTCTGTATTGTGAACTAAGACTTTCTAGAATTTTACTTATTCATTCTGTAC

>60346_60346_5_NRP1-RSU1_NRP1_chr10_33619636_ENST00000374823_RSU1_chr10_16635495_ENST00000377921_length(amino acids)=125AA_BP=
MVCEDAPSFQMAWESQMAWERGPALLCCVLSASQLSSQDQDPLGHIKSLLYPFGFPVELPRPGPTGAYKKVKNQNQTTSSELLRKQTSHF

--------------------------------------------------------------
>60346_60346_6_NRP1-RSU1_NRP1_chr10_33619636_ENST00000374867_RSU1_chr10_16635495_ENST00000377921_length(transcript)=3657nt_BP=771nt
GCAGTTGGTGAAACTCCTCTGTCTCCCGCTCATCTTTTCATTGCTCGTTCCCCTCCTTCCCGCAGACACCCGGACCTCCCCTGGGCGCCA
GCTCCGCGGCTCCAACGGGTCCAGAAACAAGCCGGATTTTTTTTTTTTCTTCCTGGAAATTGGCTTTGGTGTGTGTTGCCCTACCTCCCT
CCTCCCCCTCCCACCCACAGCCCCCCCCCGGCCTTTTTTTTTTTTTTTTTTTTTTTTGAGACATGGCCCGGGCAGTGGCTCCTGGAAGAG
GAACAAGTGTGGGAAAAGGGAGAGGAAGCCGGAGCTAAATGACAGGATGCAGGCGACTTGAGACACAAAAAGAGAAGCGTTCCTCTCGGA
TCCAGGCATTGCCTCGCTGCTTTCTTTTCTCCAAGACGGGCTGAGGATTGTACAGCTCTAGGCGGAGTTGGGGCTCTTCGGATCGCTTAG
ATTCTCCTCTTTGCTGCATTTCCCCCCACGTCCTCGTTCTCCCGCGTCTGCCTGCGGACCCGGAGAAGGGAGAATGGAGAGGGGGCTGCC
GCTCCTCTGCGCCGTGCTCGCCCTCGTCCTCGCCCCGGCCGGCGCTTTTCGCAACGATAAATGTGGCGATACTATAAAAATTGAAAGCCC
CGGGTACCTTACATCTCCTGGTTATCCTCATTCTTATCACCCAAGTGAAAAATGCGAATGGCTGATTCAGGCTCCGGACCCATACCAGAG
AATTATGATCAACTTCAACCCTCACTTCGATTTGGAGGACAGAGACTGCAACCTCTACGGCAGACACATGCAGGCCAACCCAGAACCACC
GAAGAAGAATAATGACAAATCGAAAAAGATCAGCCGGAAACCCCTGGCAGCCAAGAACAGATAAGGAAGGGATTGGCATCGGCTGGCCTT
CCAGCACCTTCTCTCTCCAACACTTCATTCTCTCTTGCCCTGTCTCTCAAATAAACCCAATGCTGCGTGTGAGGCCTTTTTTATTTTTCT
TTTCACTCTCTTTCTAATGCTTCCCACCTTACCTTTTAGATTCTTTTGCTAGGTGGGAGATTGTTATAAGGTCTTTAAACCATTTCCATT
TGTTTCTTTAACATTACCAAAAGCAGGGAACAAAGCTCTTATTCAACTGCGAATTCCATAGTGGGCTCTGGCTTTTCTTGAATAGATATC
ACAAGGTTGCTTATTATCAAAAGAATAATTAAAATCATGTAACCATTTAAATGTCACTGTTAACACTTTTCACTCTTTCTGTTGATTCAC
CTAACTCATTATTTTGCTTTATTAAAAGTCTTCCTTCACCACCGAGATATGCTAATTTAACTTACAAATGATTTTAATAAAATCTTGAGT
TTGTATCACATGTTACTTATTGACTCAGAATAAAAGAACAGTCTGATCTTGGGGTATAACACATTTTCATTTACTTTTCTCCCCCAAAAT
CATCTTATCCAATTTTATTGGTTATACATGATAAACTTTTCATGAAAGAAATGCAAAATTAAATCACAGTTCGTTTCTTCTCACATTAAT
TTGTCAAGTTTTTTTTTTCTTTGAAGACTTTCTAAATTAGGAAGCAGAAAAACAAATCTCTAGGAGATTCTGCCAAAGGATTTTGGAAAG
TAGCATTCCTTCGCCGAAGAAATGGTGATTTCTGCCAGGGGCTGGTAGACAAGAACTGTGAAAGAGAGAGAGAAAAAACCTCAACTGTGT
ATTTTGTCACGGCGGAAAATCTGCTCGCATCGAAGCATTCTTCTAAGCGACTTCGATGCCAAGGAAGTTGTGTAAATGTGCACGCGCTAC
ACCACACCCAGGGTGGAAACCACAGTTGCAGAGTCATTAAACAATCAATTGTTTGTTTAACATCTGTGATAGGCAGCTTTCCTTCTTTTC
AACAGTGATACCTACGAAAATCAAAATAAATGCAAGCTGAGGTTTTGTGCTCACTGAAAGGGCTGTCAACCCCAGAAGGCCGACACAAAA
AAAATGGTATGTGAAGATGCACCGTCTTTTCAAATGGCCTGGGAGAGTCAAATGGCCTGGGAGAGGGGGCCTGCCCTTCTCTGCTGTGTC
CTTTCGGCTTCCCAGTTGAGCTCCCAAGACCAGGACCCACTGGGGCATATAAAATCTCTGCTGTATCCTTTCGGCTTCCCAGTTGAGCTC
CCAAGACCAGGACCCACTGGGGCATATAAAAAAGTCAAAAATCAAAATCAAACAACAAGTTCTGAGTTACTTAGGAAACAGACTTCGCAT
TTCAATCAGAGAGGCCACAGAGCAAGGTCTAAACTTCTGGCTTCTAGACAAATTCCTGATAGAACATTTAAATGTGGGAAGTGGCTTCCC
CAGGTCCCATCCCCTGTTTAGGGATAGAGTTGATATCATTTTTATAGGTGCCATGTATGCCTCTGCCTGAATTTTTTTAATTGACTTTTG
AGCTTTTGAGATTGCACGAGGGAGAACAAGGCCTTTGCTGTTGTGGATAGGAAAGACTTAACCTAAAATTAAACCAGCAAGAAAGCATTA
GTAAAAATCTAACAATATGAAGGGCTCTTATGAGTCATTTTTTTCAAAAGATGAAAACTCCAGAAACGCACAGGAACGAAATACCTCCCA
GAAACATGAAGCAATCATCGAAGACTCACTGGTAATATTTTTAAAAAGTATACAGATCAAAGCAAAAAGAAGCCATGTGTAACAAAGAGA
AATGTGCAAATATTTTTTAAGGCAGTATTAAGTGCAAGAGGAGTAACATGAAATAAACATTCTTTCACATGGCTACTGGGAATATAAATT
TCGCTCCAGAAAGGCCGTAGCAGTTTGACGATAGGTGGCAAAACCTTAAGATTGTGTACTGGGGCCCAGAATTTTTATTTCTAGGAATGT
ATCCTGAGGAAATTATCCGAGATCCCCACAAACTGCAATGTTTAGGAATTGTCCTTATAGCATTGCATACACAAGAAAAACAGAGAAAAG
CCTGATCCCTGTCAGTGGAAAAGGGGTTCAATGAATTACGGTGTGTCTGCATGAGGCTTTTATGACATTAAAAATTGTTGAACAACGGCC
AGGCACAGTGGCTCATGCCTGTAATCCTAACACTTTGGGAGGCCAAGGTGGGAAGATTGCCTGAGCTCAGGAGTTTGAGACCAGCCTGGG
CAACACGGTGAAACCCCGTCTCTACTAAAATACAAAAAATTAGCCGGGCGTCGCAGCATGCGCCTGTAGTCCCAGCTGCTCAGGAGGCTG
AGGCAGGAGAATTGATTGAACCCGGGAGGCAGAGGTTGCACTGAGCTGAGATTAAGCCACCGCACTCCAGCCTGGGCGACAGAGCAAGAT
TCCGTTCCCAAGAAAAAAAAATTGTTCAACAATAAGGGCAAAGGGAGAGAATCATAACATCTGATTAAACAGAAAAAGCAAGATTTTTAA
AACTAACTATATAAGGATGGTCCCAGCTGTGTCAAAAGGAAGCTTGTTTGTAATACGTGTGCATAAAAATTAAATAGAGGTGAACACAAT
TATTTTAAGGCAGTTAAATTATCTCTGTATTGTGAACTAAGACTTTCTAGAATTTTACTTATTCATTCTGTACTTAAATTTTTTCTAATG

>60346_60346_6_NRP1-RSU1_NRP1_chr10_33619636_ENST00000374867_RSU1_chr10_16635495_ENST00000377921_length(amino acids)=207AA_BP=0
MKCWREKVLEGQPMPIPSLSVLGCQGFPADLFRFVIILLRWFWVGLHVSAVEVAVSVLQIEVRVEVDHNSLVWVRSLNQPFAFFTWVIRM
RITRRCKVPGAFNFYSIATFIVAKSAGRGEDEGEHGAEERQPPLHSPFSGSAGRRGRTRTWGEMQQRGESKRSEEPQLRLELYNPQPVLE

--------------------------------------------------------------
>60346_60346_7_NRP1-RSU1_NRP1_chr10_33619636_ENST00000395995_RSU1_chr10_16635495_ENST00000377921_length(transcript)=3134nt_BP=248nt
ATGGAGAGGGGGCTGCCGCTCCTCTGCGCCGTGCTCGCCCTCGTCCTCGCCCCGGCCGGCGCTTTTCGCAACGATAAATGTGGCGATACT
ATAAAAATTGAAAGCCCCGGGTACCTTACATCTCCTGGTTATCCTCATTCTTATCACCCAAGTGAAAAATGCGAATGGCTGATTCAGGCT
CCGGACCCATACCAGAGAATTATGATCAACTTCAACCCTCACTTCGATTTGGAGGACAGAGACTGCAACCTCTACGGCAGACACATGCAG
GCCAACCCAGAACCACCGAAGAAGAATAATGACAAATCGAAAAAGATCAGCCGGAAACCCCTGGCAGCCAAGAACAGATAAGGAAGGGAT
TGGCATCGGCTGGCCTTCCAGCACCTTCTCTCTCCAACACTTCATTCTCTCTTGCCCTGTCTCTCAAATAAACCCAATGCTGCGTGTGAG
GCCTTTTTTATTTTTCTTTTCACTCTCTTTCTAATGCTTCCCACCTTACCTTTTAGATTCTTTTGCTAGGTGGGAGATTGTTATAAGGTC
TTTAAACCATTTCCATTTGTTTCTTTAACATTACCAAAAGCAGGGAACAAAGCTCTTATTCAACTGCGAATTCCATAGTGGGCTCTGGCT
TTTCTTGAATAGATATCACAAGGTTGCTTATTATCAAAAGAATAATTAAAATCATGTAACCATTTAAATGTCACTGTTAACACTTTTCAC
TCTTTCTGTTGATTCACCTAACTCATTATTTTGCTTTATTAAAAGTCTTCCTTCACCACCGAGATATGCTAATTTAACTTACAAATGATT
TTAATAAAATCTTGAGTTTGTATCACATGTTACTTATTGACTCAGAATAAAAGAACAGTCTGATCTTGGGGTATAACACATTTTCATTTA
CTTTTCTCCCCCAAAATCATCTTATCCAATTTTATTGGTTATACATGATAAACTTTTCATGAAAGAAATGCAAAATTAAATCACAGTTCG
TTTCTTCTCACATTAATTTGTCAAGTTTTTTTTTTCTTTGAAGACTTTCTAAATTAGGAAGCAGAAAAACAAATCTCTAGGAGATTCTGC
CAAAGGATTTTGGAAAGTAGCATTCCTTCGCCGAAGAAATGGTGATTTCTGCCAGGGGCTGGTAGACAAGAACTGTGAAAGAGAGAGAGA
AAAAACCTCAACTGTGTATTTTGTCACGGCGGAAAATCTGCTCGCATCGAAGCATTCTTCTAAGCGACTTCGATGCCAAGGAAGTTGTGT
AAATGTGCACGCGCTACACCACACCCAGGGTGGAAACCACAGTTGCAGAGTCATTAAACAATCAATTGTTTGTTTAACATCTGTGATAGG
CAGCTTTCCTTCTTTTCAACAGTGATACCTACGAAAATCAAAATAAATGCAAGCTGAGGTTTTGTGCTCACTGAAAGGGCTGTCAACCCC
AGAAGGCCGACACAAAAAAAATGGTATGTGAAGATGCACCGTCTTTTCAAATGGCCTGGGAGAGTCAAATGGCCTGGGAGAGGGGGCCTG
CCCTTCTCTGCTGTGTCCTTTCGGCTTCCCAGTTGAGCTCCCAAGACCAGGACCCACTGGGGCATATAAAATCTCTGCTGTATCCTTTCG
GCTTCCCAGTTGAGCTCCCAAGACCAGGACCCACTGGGGCATATAAAAAAGTCAAAAATCAAAATCAAACAACAAGTTCTGAGTTACTTA
GGAAACAGACTTCGCATTTCAATCAGAGAGGCCACAGAGCAAGGTCTAAACTTCTGGCTTCTAGACAAATTCCTGATAGAACATTTAAAT
GTGGGAAGTGGCTTCCCCAGGTCCCATCCCCTGTTTAGGGATAGAGTTGATATCATTTTTATAGGTGCCATGTATGCCTCTGCCTGAATT
TTTTTAATTGACTTTTGAGCTTTTGAGATTGCACGAGGGAGAACAAGGCCTTTGCTGTTGTGGATAGGAAAGACTTAACCTAAAATTAAA
CCAGCAAGAAAGCATTAGTAAAAATCTAACAATATGAAGGGCTCTTATGAGTCATTTTTTTCAAAAGATGAAAACTCCAGAAACGCACAG
GAACGAAATACCTCCCAGAAACATGAAGCAATCATCGAAGACTCACTGGTAATATTTTTAAAAAGTATACAGATCAAAGCAAAAAGAAGC
CATGTGTAACAAAGAGAAATGTGCAAATATTTTTTAAGGCAGTATTAAGTGCAAGAGGAGTAACATGAAATAAACATTCTTTCACATGGC
TACTGGGAATATAAATTTCGCTCCAGAAAGGCCGTAGCAGTTTGACGATAGGTGGCAAAACCTTAAGATTGTGTACTGGGGCCCAGAATT
TTTATTTCTAGGAATGTATCCTGAGGAAATTATCCGAGATCCCCACAAACTGCAATGTTTAGGAATTGTCCTTATAGCATTGCATACACA
AGAAAAACAGAGAAAAGCCTGATCCCTGTCAGTGGAAAAGGGGTTCAATGAATTACGGTGTGTCTGCATGAGGCTTTTATGACATTAAAA
ATTGTTGAACAACGGCCAGGCACAGTGGCTCATGCCTGTAATCCTAACACTTTGGGAGGCCAAGGTGGGAAGATTGCCTGAGCTCAGGAG
TTTGAGACCAGCCTGGGCAACACGGTGAAACCCCGTCTCTACTAAAATACAAAAAATTAGCCGGGCGTCGCAGCATGCGCCTGTAGTCCC
AGCTGCTCAGGAGGCTGAGGCAGGAGAATTGATTGAACCCGGGAGGCAGAGGTTGCACTGAGCTGAGATTAAGCCACCGCACTCCAGCCT
GGGCGACAGAGCAAGATTCCGTTCCCAAGAAAAAAAAATTGTTCAACAATAAGGGCAAAGGGAGAGAATCATAACATCTGATTAAACAGA
AAAAGCAAGATTTTTAAAACTAACTATATAAGGATGGTCCCAGCTGTGTCAAAAGGAAGCTTGTTTGTAATACGTGTGCATAAAAATTAA
ATAGAGGTGAACACAATTATTTTAAGGCAGTTAAATTATCTCTGTATTGTGAACTAAGACTTTCTAGAATTTTACTTATTCATTCTGTAC

>60346_60346_7_NRP1-RSU1_NRP1_chr10_33619636_ENST00000395995_RSU1_chr10_16635495_ENST00000377921_length(amino acids)=125AA_BP=
MVCEDAPSFQMAWESQMAWERGPALLCCVLSASQLSSQDQDPLGHIKSLLYPFGFPVELPRPGPTGAYKKVKNQNQTTSSELLRKQTSHF

--------------------------------------------------------------
>60346_60346_8_NRP1-RSU1_NRP1_chr10_33619636_ENST00000432372_RSU1_chr10_16635495_ENST00000602389_length(transcript)=3672nt_BP=795nt
GCAGGGTCTCTGGGAAAGACAGACAGACGGACGGGGAGAGCACTCGGAGGGAAAGTTGTTCCTCCCAGTCTCCTGTCAGGCAATTACAGA
CACCCGGACCTCCCCTGGGCGCCAGCTCCGCGGCTCCAACGGGTCCAGAAACAAGCCGGATTTTTTTTTTTTCTTCCTGGAAATTGGCTT
TGGTGTGTGTTGCCCTACCTCCCTCCTCCCCCTCCCACCCACAGCCCCCCCCCGGCCTTTTTTTTTTTTTTTTTTTTTTTTGAGACATGG
CCCGGGCAGTGGCTCCTGGAAGAGGAACAAGTGTGGGAAAAGGGAGAGGAAGCCGGAGCTAAATGACAGGATGCAGGCGACTTGAGACAC
AAAAAGAGAAGCGTTCCTCTCGGATCCAGGCATTGCCTCGCTGCTTTCTTTTCTCCAAGACGGGCTGAGGATTGTACAGCTCTAGGCGGA
GTTGGGGCTCTTCGGATCGCTTAGATTCTCCTCTTTGCTGCATTTCCCCCCACGTCCTCGTTCTCCCGCGTCTGCCTGCGGACCCGGAGA
AGGGAGAATGGAGAGGGGGCTGCCGCTCCTCTGCGCCGTGCTCGCCCTCGTCCTCGCCCCGGCCGGCGCTTTTCGCAACGATAAATGTGG
CGATACTATAAAAATTGAAAGCCCCGGGTACCTTACATCTCCTGGTTATCCTCATTCTTATCACCCAAGTGAAAAATGCGAATGGCTGAT
TCAGGCTCCGGACCCATACCAGAGAATTATGATCAACTTCAACCCTCACTTCGATTTGGAGGACAGAGACTGCAACCTCTACGGCAGACA
CATGCAGGCCAACCCAGAACCACCGAAGAAGAATAATGACAAATCGAAAAAGATCAGCCGGAAACCCCTGGCAGCCAAGAACAGATAAGG
AAGGGATTGGCATCGGCTGGCCTTCCAGCACCTTCTCTCTCCAACACTTCATTCTCTCTTGCCCTGTCTCTCAAATAAACCCAATGCTGC
GTGTGAGGCCTTTTTTATTTTTCTTTTCACTCTCTTTCTAATGCTTCCCACCTTACCTTTTAGATTCTTTTGCTAGGTGGGAGATTGTTA
TAAGGTCTTTAAACCATTTCCATTTGTTTCTTTAACATTACCAAAAGCAGGGAACAAAGCTCTTATTCAACTGCGAATTCCATAGTGGGC
TCTGGCTTTTCTTGAATAGATATCACAAGGTTGCTTATTATCAAAAGAATAATTAAAATCATGTAACCATTTAAATGTCACTGTTAACAC
TTTTCACTCTTTCTGTTGATTCACCTAACTCATTATTTTGCTTTATTAAAAGTCTTCCTTCACCACCGAGATATGCTAATTTAACTTACA
AATGATTTTAATAAAATCTTGAGTTTGTATCACATGTTACTTATTGACTCAGAATAAAAGAACAGTCTGATCTTGGGGTATAACACATTT
TCATTTACTTTTCTCCCCCAAAATCATCTTATCCAATTTTATTGGTTATACATGATAAACTTTTCATGAAAGAAATGCAAAATTAAATCA
CAGTTCGTTTCTTCTCACATTAATTTGTCAAGTTTTTTTTTTCTTTGAAGACTTTCTAAATTAGGAAGCAGAAAAACAAATCTCTAGGAG
ATTCTGCCAAAGGATTTTGGAAAGTAGCATTCCTTCGCCGAAGAAATGGTGATTTCTGCCAGGGGCTGGTAGACAAGAACTGTGAAAGAG
AGAGAGAAAAAACCTCAACTGTGTATTTTGTCACGGCGGAAAATCTGCTCGCATCGAAGCATTCTTCTAAGCGACTTCGATGCCAAGGAA
GTTGTGTAAATGTGCACGCGCTACACCACACCCAGGGTGGAAACCACAGTTGCAGAGTCATTAAACAATCAATTGTTTGTTTAACATCTG
TGATAGGCAGCTTTCCTTCTTTTCAACAGTGATACCTACGAAAATCAAAATAAATGCAAGCTGAGGTTTTGTGCTCACTGAAAGGGCTGT
CAACCCCAGAAGGCCGACACAAAAAAAATGGTATGTGAAGATGCACCGTCTTTTCAAATGGCCTGGGAGAGTCAAATGGCCTGGGAGAGG
GGGCCTGCCCTTCTCTGCTGTGTCCTTTCGGCTTCCCAGTTGAGCTCCCAAGACCAGGACCCACTGGGGCATATAAAATCTCTGCTGTAT
CCTTTCGGCTTCCCAGTTGAGCTCCCAAGACCAGGACCCACTGGGGCATATAAAAAAGTCAAAAATCAAAATCAAACAACAAGTTCTGAG
TTACTTAGGAAACAGACTTCGCATTTCAATCAGAGAGGCCACAGAGCAAGGTCTAAACTTCTGGCTTCTAGACAAATTCCTGATAGAACA
TTTAAATGTGGGAAGTGGCTTCCCCAGGTCCCATCCCCTGTTTAGGGATAGAGTTGATATCATTTTTATAGGTGCCATGTATGCCTCTGC
CTGAATTTTTTTAATTGACTTTTGAGCTTTTGAGATTGCACGAGGGAGAACAAGGCCTTTGCTGTTGTGGATAGGAAAGACTTAACCTAA
AATTAAACCAGCAAGAAAGCATTAGTAAAAATCTAACAATATGAAGGGCTCTTATGAGTCATTTTTTTCAAAAGATGAAAACTCCAGAAA
CGCACAGGAACGAAATACCTCCCAGAAACATGAAGCAATCATCGAAGACTCACTGGTAATATTTTTAAAAAGTATACAGATCAAAGCAAA
AAGAAGCCATGTGTAACAAAGAGAAATGTGCAAATATTTTTTAAGGCAGTATTAAGTGCAAGAGGAGTAACATGAAATAAACATTCTTTC
ACATGGCTACTGGGAATATAAATTTCGCTCCAGAAAGGCCGTAGCAGTTTGACGATAGGTGGCAAAACCTTAAGATTGTGTACTGGGGCC
CAGAATTTTTATTTCTAGGAATGTATCCTGAGGAAATTATCCGAGATCCCCACAAACTGCAATGTTTAGGAATTGTCCTTATAGCATTGC
ATACACAAGAAAAACAGAGAAAAGCCTGATCCCTGTCAGTGGAAAAGGGGTTCAATGAATTACGGTGTGTCTGCATGAGGCTTTTATGAC
ATTAAAAATTGTTGAACAACGGCCAGGCACAGTGGCTCATGCCTGTAATCCTAACACTTTGGGAGGCCAAGGTGGGAAGATTGCCTGAGC
TCAGGAGTTTGAGACCAGCCTGGGCAACACGGTGAAACCCCGTCTCTACTAAAATACAAAAAATTAGCCGGGCGTCGCAGCATGCGCCTG
TAGTCCCAGCTGCTCAGGAGGCTGAGGCAGGAGAATTGATTGAACCCGGGAGGCAGAGGTTGCACTGAGCTGAGATTAAGCCACCGCACT
CCAGCCTGGGCGACAGAGCAAGATTCCGTTCCCAAGAAAAAAAAATTGTTCAACAATAAGGGCAAAGGGAGAGAATCATAACATCTGATT
AAACAGAAAAAGCAAGATTTTTAAAACTAACTATATAAGGATGGTCCCAGCTGTGTCAAAAGGAAGCTTGTTTGTAATACGTGTGCATAA
AAATTAAATAGAGGTGAACACAATTATTTTAAGGCAGTTAAATTATCTCTGTATTGTGAACTAAGACTTTCTAGAATTTTACTTATTCAT

>60346_60346_8_NRP1-RSU1_NRP1_chr10_33619636_ENST00000432372_RSU1_chr10_16635495_ENST00000602389_length(amino acids)=207AA_BP=0
MKCWREKVLEGQPMPIPSLSVLGCQGFPADLFRFVIILLRWFWVGLHVSAVEVAVSVLQIEVRVEVDHNSLVWVRSLNQPFAFFTWVIRM
RITRRCKVPGAFNFYSIATFIVAKSAGRGEDEGEHGAEERQPPLHSPFSGSAGRRGRTRTWGEMQQRGESKRSEEPQLRLELYNPQPVLE

--------------------------------------------------------------

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Fusion Gene PPI Analysis for NRP1-RSU1


check button Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in

ChiPPI page.


check button Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160)
HgeneHgene's interactorsTgeneTgene's interactors


check button - Retained PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenStill interaction with


check button - Lost PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


check button - Retained PPIs, but lost function due to frame-shift fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


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Related Drugs for NRP1-RSU1


check button Drugs targeting genes involved in this fusion gene.
(DrugBank Version 5.1.8 2021-05-08)
PartnerGeneUniProtAccDrugBank IDDrug nameDrug activityDrug typeDrug status

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Related Diseases for NRP1-RSU1


check button Diseases associated with fusion partners.
(DisGeNet 4.0)
PartnerGeneDisease IDDisease name# pubmedsSource