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Center for Computational Systems Medicine
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Fusion Gene Summary

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Fusion Gene ORF analysis

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Fusion Genomic Features

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Fusion Protein Features

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Fusion Gene Sequence

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Fusion Gene PPI analysis

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Related Drugs

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Related Diseases

Fusion gene:NRXN3-FERMT2 (FusionGDB2 ID:60382)

Fusion Gene Summary for NRXN3-FERMT2

check button Fusion gene summary
Fusion gene informationFusion gene name: NRXN3-FERMT2
Fusion gene ID: 60382
HgeneTgene
Gene symbol

NRXN3

FERMT2

Gene ID

9369

10979

Gene nameneurexin 3fermitin family member 2
SynonymsC14orf60KIND2|MIG2|PLEKHC1|UNC112|UNC112B|mig-2
Cytomap

14q24.3-q31.1

14q22.1

Type of geneprotein-codingprotein-coding
Descriptionneurexin 3neurexin IIIneurexin-3-alphafermitin family homolog 2PH domain-containing family C member 1kindlin 2mitogen inducible gene 2 proteinpleckstrin homology domain containing, family C (with FERM domain) member 1pleckstrin homology domain containing, family C member 1
Modification date2020031320200313
UniProtAcc.

Q96AC1

Ensembl transtripts involved in fusion geneENST00000281127, ENST00000335750, 
ENST00000428277, ENST00000554719, 
ENST00000556003, ENST00000557594, 
ENST00000557255, ENST00000341590, 
ENST00000343279, ENST00000395631, 
ENST00000399304, ENST00000553373, 
Fusion gene scores* DoF score14 X 14 X 5=9808 X 8 X 6=384
# samples 148
** MAII scorelog2(14/980*10)=-2.8073549220576
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0		log2(8/384*10)=-2.26303440583379
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0
Context

PubMed: NRXN3 [Title/Abstract] AND FERMT2 [Title/Abstract] AND fusion [Title/Abstract]

Most frequent breakpointNRXN3(80271542)-FERMT2(53348187), # samples:1
Anticipated loss of major functional domain due to fusion event.
* DoF score (Degree of Frequency) = # partners X # break points X # cancer types
** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)

check button Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez
PartnerGeneGO IDGO termPubMed ID

check buttonFusion gene breakpoints across NRXN3 (5'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check buttonFusion gene breakpoints across FERMT2 (3'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check button Fusion gene information from two resources (ChiTars 5.0 and ChimerDB 4.0)
* All genome coordinats were lifted-over on hg19.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
SourceDiseaseSampleHgeneHchrHbpHstrandTgeneTchrTbpTstrand
ChimerDB4STADTCGA-CD-5803-01ANRXN3chr14

80271542

+FERMT2chr14

53348187

-


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Fusion Gene ORF analysis for NRXN3-FERMT2

check button Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
ORFHenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrand
5CDS-intronENST00000281127ENST00000557255NRXN3chr14

80271542

+FERMT2chr14

53348187

-
In-frameENST00000281127ENST00000341590NRXN3chr14

80271542

+FERMT2chr14

53348187

-
In-frameENST00000281127ENST00000343279NRXN3chr14

80271542

+FERMT2chr14

53348187

-
In-frameENST00000281127ENST00000395631NRXN3chr14

80271542

+FERMT2chr14

53348187

-
In-frameENST00000281127ENST00000399304NRXN3chr14

80271542

+FERMT2chr14

53348187

-
In-frameENST00000281127ENST00000553373NRXN3chr14

80271542

+FERMT2chr14

53348187

-
intron-3CDSENST00000335750ENST00000341590NRXN3chr14

80271542

+FERMT2chr14

53348187

-
intron-3CDSENST00000335750ENST00000343279NRXN3chr14

80271542

+FERMT2chr14

53348187

-
intron-3CDSENST00000335750ENST00000395631NRXN3chr14

80271542

+FERMT2chr14

53348187

-
intron-3CDSENST00000335750ENST00000399304NRXN3chr14

80271542

+FERMT2chr14

53348187

-
intron-3CDSENST00000335750ENST00000553373NRXN3chr14

80271542

+FERMT2chr14

53348187

-
intron-3CDSENST00000428277ENST00000341590NRXN3chr14

80271542

+FERMT2chr14

53348187

-
intron-3CDSENST00000428277ENST00000343279NRXN3chr14

80271542

+FERMT2chr14

53348187

-
intron-3CDSENST00000428277ENST00000395631NRXN3chr14

80271542

+FERMT2chr14

53348187

-
intron-3CDSENST00000428277ENST00000399304NRXN3chr14

80271542

+FERMT2chr14

53348187

-
intron-3CDSENST00000428277ENST00000553373NRXN3chr14

80271542

+FERMT2chr14

53348187

-
intron-3CDSENST00000554719ENST00000341590NRXN3chr14

80271542

+FERMT2chr14

53348187

-
intron-3CDSENST00000554719ENST00000343279NRXN3chr14

80271542

+FERMT2chr14

53348187

-
intron-3CDSENST00000554719ENST00000395631NRXN3chr14

80271542

+FERMT2chr14

53348187

-
intron-3CDSENST00000554719ENST00000399304NRXN3chr14

80271542

+FERMT2chr14

53348187

-
intron-3CDSENST00000554719ENST00000553373NRXN3chr14

80271542

+FERMT2chr14

53348187

-
intron-3CDSENST00000556003ENST00000341590NRXN3chr14

80271542

+FERMT2chr14

53348187

-
intron-3CDSENST00000556003ENST00000343279NRXN3chr14

80271542

+FERMT2chr14

53348187

-
intron-3CDSENST00000556003ENST00000395631NRXN3chr14

80271542

+FERMT2chr14

53348187

-
intron-3CDSENST00000556003ENST00000399304NRXN3chr14

80271542

+FERMT2chr14

53348187

-
intron-3CDSENST00000556003ENST00000553373NRXN3chr14

80271542

+FERMT2chr14

53348187

-
intron-3CDSENST00000557594ENST00000341590NRXN3chr14

80271542

+FERMT2chr14

53348187

-
intron-3CDSENST00000557594ENST00000343279NRXN3chr14

80271542

+FERMT2chr14

53348187

-
intron-3CDSENST00000557594ENST00000395631NRXN3chr14

80271542

+FERMT2chr14

53348187

-
intron-3CDSENST00000557594ENST00000399304NRXN3chr14

80271542

+FERMT2chr14

53348187

-
intron-3CDSENST00000557594ENST00000553373NRXN3chr14

80271542

+FERMT2chr14

53348187

-
intron-intronENST00000335750ENST00000557255NRXN3chr14

80271542

+FERMT2chr14

53348187

-
intron-intronENST00000428277ENST00000557255NRXN3chr14

80271542

+FERMT2chr14

53348187

-
intron-intronENST00000554719ENST00000557255NRXN3chr14

80271542

+FERMT2chr14

53348187

-
intron-intronENST00000556003ENST00000557255NRXN3chr14

80271542

+FERMT2chr14

53348187

-
intron-intronENST00000557594ENST00000557255NRXN3chr14

80271542

+FERMT2chr14

53348187

-

check buttonORFfinder result based on the fusion transcript sequence of in-frame fusion genes.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandSeq length
(transcript)		BP loci
(transcript)		Predicted start
(transcript)		Predicted stop
(transcript)		Seq length
(amino acids)
ENST00000281127NRXN3chr1480271542+ENST00000395631FERMT2chr1453348187-450218768733392839
ENST00000281127NRXN3chr1480271542+ENST00000341590FERMT2chr1453348187-450218768733392839
ENST00000281127NRXN3chr1480271542+ENST00000343279FERMT2chr1453348187-451618768733413846
ENST00000281127NRXN3chr1480271542+ENST00000553373FERMT2chr1453348187-341418768733413846
ENST00000281127NRXN3chr1480271542+ENST00000399304FERMT2chr1453348187-332518768733251792

check buttonDeepORF prediction of the coding potential based on the fusion transcript sequence of in-frame fusion genes. DeepORF is a coding potential classifier based on convolutional neural network by comparing the real Ribo-seq data. If the no-coding score < 0.5 and coding score > 0.5, then the in-frame fusion transcript is predicted as being likely translated.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandNo-coding scoreCoding score
ENST00000281127ENST00000395631NRXN3chr1480271542+FERMT2chr1453348187-0.00129150.9987085
ENST00000281127ENST00000341590NRXN3chr1480271542+FERMT2chr1453348187-0.00129150.9987085
ENST00000281127ENST00000343279NRXN3chr1480271542+FERMT2chr1453348187-0.0012045030.9987955
ENST00000281127ENST00000553373NRXN3chr1480271542+FERMT2chr1453348187-0.0028380490.997162
ENST00000281127ENST00000399304NRXN3chr1480271542+FERMT2chr1453348187-0.003109050.99689096

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Fusion Genomic Features for NRXN3-FERMT2


check buttonFusionAI prediction of the potential fusion gene breakpoint based on the pre-mature RNA sequence context (+/- 5kb of individual partner genes, total 20kb length sequence). FusionAI is a fusion gene breakpoint classifier based on convolutional neural network by comparing the fusion positive and negative sequence context of ~ 20K fusion gene data. From here, we can have the relative potentency of the 20K genomic sequence how individual sequnce will be likely used as the gene fusion breakpoints.
HgeneHchrHbpHstrandTgeneTchrTbpTstrand1-pp (fusion gene breakpoint)

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions. We integrated a total of 44 different types of human genomic feature loci information across five big categories including virus integration sites, repeats, structural variants, chromatin states, and gene expression regulation. More details are in help page.
genomic feature

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions that are ovelapped with the top 1% feature importance score regions. More details are in help page.

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Fusion Protein Features for NRXN3-FERMT2


check button Four levels of functional features of fusion genes
Go to FGviewer search page for the most frequent breakpoint (https://ccsmweb.uth.edu/FGviewer/chr14:80271542/chr14:53348187)
- FGviewer provides the online visualization of the retention search of the protein functional features across DNA, RNA, protein, and pathological levels.
- How to search
1. Put your fusion gene symbol.
2. Press the tab key until there will be shown the breakpoint information filled.
4. Go down and press 'Search' tab twice.
4. Go down to have the hyperlink of the search result.
5. Click the hyperlink.
6. See the FGviewer result for your fusion gene.
FGviewer

check buttonMain function of each fusion partner protein. (from UniProt)
HgeneTgene
.FERMT2

Q96AC1

FUNCTION: Transcriptional activator which is required for calcium-dependent dendritic growth and branching in cortical neurons. Recruits CREB-binding protein (CREBBP) to nuclear bodies. Component of the CREST-BRG1 complex, a multiprotein complex that regulates promoter activation by orchestrating a calcium-dependent release of a repressor complex and a recruitment of an activator complex. In resting neurons, transcription of the c-FOS promoter is inhibited by BRG1-dependent recruitment of a phospho-RB1-HDAC1 repressor complex. Upon calcium influx, RB1 is dephosphorylated by calcineurin, which leads to release of the repressor complex. At the same time, there is increased recruitment of CREBBP to the promoter by a CREST-dependent mechanism, which leads to transcriptional activation. The CREST-BRG1 complex also binds to the NR2B promoter, and activity-dependent induction of NR2B expression involves a release of HDAC1 and recruitment of CREBBP (By similarity). {ECO:0000250}.FUNCTION: Scaffolding protein that enhances integrin activation mediated by TLN1 and/or TLN2, but activates integrins only weakly by itself. Binds to membranes enriched in phosphoinositides. Enhances integrin-mediated cell adhesion onto the extracellular matrix and cell spreading; this requires both its ability to interact with integrins and with phospholipid membranes. Required for the assembly of focal adhesions. Participates in the connection between extracellular matrix adhesion sites and the actin cytoskeleton and also in the orchestration of actin assembly and cell shape modulation. Recruits FBLIM1 to focal adhesions. Plays a role in the TGFB1 and integrin signaling pathways. Stabilizes active CTNNB1 and plays a role in the regulation of transcription mediated by CTNNB1 and TCF7L2/TCF4 and in Wnt signaling. {ECO:0000269|PubMed:12679033, ECO:0000269|PubMed:18458155, ECO:0000269|PubMed:21325030, ECO:0000269|PubMed:22030399, ECO:0000269|PubMed:22078565, ECO:0000269|PubMed:22699938}.

check buttonRetention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at

download page


* Minus value of BPloci means that the break pointn is located before the CDS.
- In-frame and retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneNRXN3chr14:80271542chr14:53348187ENST00000281127+5685_255332433.0DomainLaminin G-like
TgeneFERMT2chr14:80271542chr14:53348187ENST00000341590315189_661175681.0DomainNote=FERM
TgeneFERMT2chr14:80271542chr14:53348187ENST00000341590315380_476175681.0DomainPH
TgeneFERMT2chr14:80271542chr14:53348187ENST00000343279316189_661175688.0DomainNote=FERM
TgeneFERMT2chr14:80271542chr14:53348187ENST00000343279316380_476175688.0DomainPH
TgeneFERMT2chr14:80271542chr14:53348187ENST00000395631315189_661175681.0DomainNote=FERM
TgeneFERMT2chr14:80271542chr14:53348187ENST00000395631315380_476175681.0DomainPH
TgeneFERMT2chr14:80271542chr14:53348187ENST00000399304315189_661175634.0DomainNote=FERM
TgeneFERMT2chr14:80271542chr14:53348187ENST00000399304315380_476175634.0DomainPH
TgeneFERMT2chr14:80271542chr14:53348187ENST00000553373215189_661175688.0DomainNote=FERM
TgeneFERMT2chr14:80271542chr14:53348187ENST00000553373215380_476175688.0DomainPH

- In-frame and not-retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneNRXN3chr14:80271542chr14:53348187ENST00000335750+1171049_108601062.0DomainEGF-like 3
HgeneNRXN3chr14:80271542chr14:53348187ENST00000335750+1171090_126001062.0DomainLaminin G-like 6
HgeneNRXN3chr14:80271542chr14:53348187ENST00000335750+117198_23501062.0DomainEGF-like 1
HgeneNRXN3chr14:80271542chr14:53348187ENST00000335750+117258_44001062.0DomainLaminin G-like 2
HgeneNRXN3chr14:80271542chr14:53348187ENST00000335750+11728_20201062.0DomainLaminin G-like 1
HgeneNRXN3chr14:80271542chr14:53348187ENST00000335750+117447_63901062.0DomainLaminin G-like 3
HgeneNRXN3chr14:80271542chr14:53348187ENST00000335750+117643_68001062.0DomainEGF-like 2
HgeneNRXN3chr14:80271542chr14:53348187ENST00000335750+117685_85701062.0DomainLaminin G-like 4
HgeneNRXN3chr14:80271542chr14:53348187ENST00000335750+117871_104601062.0DomainLaminin G-like 5
HgeneNRXN3chr14:80271542chr14:53348187ENST00000428277+1785_2550460.0DomainLaminin G-like
HgeneNRXN3chr14:80271542chr14:53348187ENST00000554719+1171049_108601062.0DomainEGF-like 3
HgeneNRXN3chr14:80271542chr14:53348187ENST00000554719+1171090_126001062.0DomainLaminin G-like 6
HgeneNRXN3chr14:80271542chr14:53348187ENST00000554719+117198_23501062.0DomainEGF-like 1
HgeneNRXN3chr14:80271542chr14:53348187ENST00000554719+117258_44001062.0DomainLaminin G-like 2
HgeneNRXN3chr14:80271542chr14:53348187ENST00000554719+11728_20201062.0DomainLaminin G-like 1
HgeneNRXN3chr14:80271542chr14:53348187ENST00000554719+117447_63901062.0DomainLaminin G-like 3
HgeneNRXN3chr14:80271542chr14:53348187ENST00000554719+117643_68001062.0DomainEGF-like 2
HgeneNRXN3chr14:80271542chr14:53348187ENST00000554719+117685_85701062.0DomainLaminin G-like 4
HgeneNRXN3chr14:80271542chr14:53348187ENST00000554719+117871_104601062.0DomainLaminin G-like 5
HgeneNRXN3chr14:80271542chr14:53348187ENST00000557594+1685_2550638.0DomainLaminin G-like
HgeneNRXN3chr14:80271542chr14:53348187ENST00000281127+5636_562332433.0Topological domainExtracellular
HgeneNRXN3chr14:80271542chr14:53348187ENST00000281127+56584_637332433.0Topological domainCytoplasmic
HgeneNRXN3chr14:80271542chr14:53348187ENST00000335750+1171590_164301062.0Topological domainCytoplasmic
HgeneNRXN3chr14:80271542chr14:53348187ENST00000335750+11728_156801062.0Topological domainExtracellular
HgeneNRXN3chr14:80271542chr14:53348187ENST00000428277+1736_5620460.0Topological domainExtracellular
HgeneNRXN3chr14:80271542chr14:53348187ENST00000428277+17584_6370460.0Topological domainCytoplasmic
HgeneNRXN3chr14:80271542chr14:53348187ENST00000554719+1171590_164301062.0Topological domainCytoplasmic
HgeneNRXN3chr14:80271542chr14:53348187ENST00000554719+11728_156801062.0Topological domainExtracellular
HgeneNRXN3chr14:80271542chr14:53348187ENST00000557594+1636_5620638.0Topological domainExtracellular
HgeneNRXN3chr14:80271542chr14:53348187ENST00000557594+16584_6370638.0Topological domainCytoplasmic
HgeneNRXN3chr14:80271542chr14:53348187ENST00000281127+56563_583332433.0TransmembraneHelical
HgeneNRXN3chr14:80271542chr14:53348187ENST00000335750+1171569_158901062.0TransmembraneHelical
HgeneNRXN3chr14:80271542chr14:53348187ENST00000428277+17563_5830460.0TransmembraneHelical
HgeneNRXN3chr14:80271542chr14:53348187ENST00000554719+1171569_158901062.0TransmembraneHelical
HgeneNRXN3chr14:80271542chr14:53348187ENST00000557594+16563_5830638.0TransmembraneHelical


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Fusion Gene Sequence for NRXN3-FERMT2


check button For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. To have fusion amino acid sequence, we ran ORFfinder and chose the longest ORF among the all predicted ones.
>60382_60382_1_NRXN3-FERMT2_NRXN3_chr14_80271542_ENST00000281127_FERMT2_chr14_53348187_ENST00000341590_length(transcript)=4502nt_BP=1876nt
ACTTCGCAGGCGCCCGCCCGCCTCTCGGCCACCTCTGCAGCCTGCCAGGCACCTCCTCTTGCGCTCTCGCTGATTTCGCCCACCCACCTC
CCTCCACCCCGTGCCACGTTGGTTTGGGTGGCTGCTCCGCACCGGGTTCCTCCTCCTCTCCTCTTTCCCTCCAGTCCTTCTTATTCTCTT
CCTCTGGCTGCGGTGGCTGCTGCTGCTGCTGGTTTTCATCCAGTTGGGAAACCCAGGAAGCCGGCGGCTGCTCCGTGGCGCTAGTCCAGC
ACGCCCAGGGTTAAAAGCCTCGCGCCCTTCCGCGGAGACTCCCAGGAACACCCGAAGAACTCTTCCACCTGCAGCCCCCTTTTGCCTGGC
AGTTCTGCATTGCATCTCATGGAAGTGGAAACAGGAAAATAAAAATGTTCAAACTCCTTGGATGTTGGGATAAACTCACCTGAACCCACT
TGGGTTCGGGCTGCCTCCTTCTCTTCCTTCATTGCCACCTTTCCTCTGTGTGGCTCCCGGGAGTGTGCGGTTAAGTCATCAGACTCGAAG
TGCCTAGAGATCCGGAGGAAGCCGCGCCGGTCTTCCCCTGACATGCGTGGCATGCCGGGGCTCCGTAGGAGGTTTGCTATACCTGGGAGG
ACCCTGGCATTCTAAATTTCAGCTCCGGGAAAGAGAAGGGGCTTTTTGCCTTTTATCTTTTTTTTTTCTTTCTTTAAGTAGTAATTTTTT
AACTGATTCATTGTTTGGAAAGCGCATATTGCTTCCCTCTTCCCCGAATTCTGGCAACTCTTCCTCCTGCTATGATGGGCCCTTGGGCAT
CATGAACTTCATTACTCCTCACTGGCTGGAATTCAAACTGCCCATCTGTAGTGGTCCCGTGCGTTGACCATGCACCTGAGAATCCACGCG
AGACGGAGCCCTCCTCGCCGGCCGGCCTGGACGCTTGGGATCTGGTTCCTGTTCTGGGGATGTATCGTCAGCTCTGTATGGAGTTCTTCT
AATGTAGCTTCCTCCTCCTCCACCTCTTCCTCGCCGGGGTCTCACTCTCAGCACGAGCACCATTTCCATGGCAGCAAGCATCACTCAGTG
CCTATTTCTATCTATCGTTCCCCTGTTTCCCTTCGAGGAGGACACGCTGGCGCTACGTACATCTTTGGGAAAAGTGGTGGGCTTATCCTC
TACACCTGGCCAGCCAATGACAGGCCCAGCACGCGGTCTGACCGCCTTGCCGTGGGCTTCAGCACCACTGTGAAGGATGGCATCTTGGTC
CGCATCGACAGTGCTCCAGGACTTGGTGACTTCCTCCAGCTTCACATAGAACAGGGGAAAATTGGAGTTGTCTTCAACATTGGCACAGTT
GACATCTCCATCAAAGAGGAGAGAACCCCTGTAAATGACGGCAAATACCATGTGGTACGCTTCACCAGGAACGGCGGCAACGCCACCCTG
CAGGTGGACAACTGGCCAGTGAATGAACATTATCCTACAGGCCGGCAGTTAACCATCTTCAACACTCAGGCGCAAATAGCCATTGGTGGA
AAGGACAAAGGACGCCTCTTCCAAGGCCAACTCTCTGGGCTCTATTATGATGGTTTGAAAGTACTGAACATGGCGGCTGAGAACAACCCC
AATATTAAAATCAATGGAAGTGTTCGGCTGGTTGGAGAAGTCCCATCAATTTTGGGAACAACACAGACGACCTCCATGCCACCAGAAATG
TCTACTACTGTCATGGAAACCACTACTACAATGGCGACTACCACAACCCGTAAGAATCGCTCTACAGCCAGCATTCAGCCAACATCAGAT
GATCTTGTTTCATCTGCTGAATGTTCAAGTGATGATGAAGACTTTGTTGAATGTGAGCCGAGTACAGGTAGGTCAGGAAGTATATATTCA
AGCCCAGGACTGTATAGTAAAACAATGACCCCCACTTATGATGCTCATGATGGAAGCCCCTTGTCACCAACTTCTGCTTGGTTTGGTGAC
AGTGCTTTGTCAGAAGGCAATCCTGGTATACTTGCTGTCAGTCAACCAATCACGTCACCAGAAATCTTGGCAAAAATGTTCAAGCCTCAA
GCTCTTCTTGATAAAGCAAAAATCAACCAAGGATGGCTTGATTCCTCAAGATCTCTCATGGAACAAGATGTGAAGGAAAATGAGGCCTTG
CTGCTCCGATTCAAGTATTACAGCTTTTTTGATTTGAATCCAAAGTATGATGCAATCAGAATCAATCAGCTTTACGAGCAGGCCAAATGG
GCCATTCTCCTGGAAGAGATTGAATGCACAGAAGAAGAAATGATGATGTTTGCAGCCCTGCAGTATCATATCAATAAGCTGTCAATCATG
ACATCAGAGAATCATTTGAACAACAGTGACAAAGAAGTTGATGAAGTTGATGCTGCCCTTTCAGACCTGGAGATTACTCTGGAAGGGGGT
AAAACGTCAACAATTTTGGGTGACATTACTTCCATTCCTGAACTTGCTGACTACATTAAAGTTTTCAAGCCAAAAAAGCTGACTCTGAAA
GGTTACAAACAATATTGGTGCACCTTCAAAGACACATCCATTTCTTGTTATAAGAGCAAAGAAGAATCCAGTGGCACACCAGCTCATCAG
ATGAACCTCAGGGGATGTGAAGTTACCCCAGATGTAAACATTTCAGGCCAAAAATTTAACATTAAACTCCTGATTCCAGTTGCAGAAGGC
ATGAATGAAATCTGGCTTCGTTGTGACAATGAAAAACAGTATGCACACTGGATGGCAGCCTGCAGATTAGCCTCCAAAGGCAAGACCATG
GCGGACAGTTCTTACAACTTAGAAGTTCAGAATATTCTTTCCTTTCTGAAGATGCAGCATTTAAACCCAGATCCTCAGTTAATACCAGAG
CAGATCACGACTGATATAACTCCTGAATGTTTGGTGTCTCCCCGCTATCTAAAAAAGTATAAGAACAAGCAGATAACAGCGAGAATCTTG
GAGGCCCATCAGAATGTAGCTCAGATGAGTCTAATTGAAGCCAAGATGAGATTTATTCAAGCTTGGCAGTCACTACCTGAATTTGGCATC
ACTCACTTCATTGCAAGGTTCCAAGGGGGCAAAAAAGAAGAACTTATTGGAATTGCATACAACAGACTGATTCGGATGGATGCCAGCACT
GGAGATGCAATTAAAACATGGCGTTTCAGCAACATGAAACAGTGGAATGTCAACTGGGAAATCAAAATGGTCACCGTAGAGTTTGCAGAT
GAAGTACGATTGTCCTTCATTTGTACTGAAGTAGATTGCAAAGTGGTTCATGAATTCATTGGTGGCTACATATTTCTCTCAACACGTGCA
AAAGACCAAAACGAGAGTTTAGATGAAGAGATGTTCTACAAACTTACCAGTGGTTGGGTGTGAATAGGAATACTGTTTAATGAAACTCCA
CGGCCATAACAATATTTAACTTTAAAAGCTGTTTGTTATATGCTGCTTAATAAAGTAAGCTTGAAATTTATCATTTTATCATGAAAACTT
CTTTGCCTTACCAGACCAGTTAATATGTGCACTAAACAAGCACGACTATTAATCTATCATGTTATGATATAATAAACTTGAATTTGTCAC
ACATTCCTTAGGGCCATGAATTGAAAACTGAAATAGTGGGCAAATCAGGAACAAACCATCACTGATTTACTGATTTAAGCTAGCCAAACT
GTAAGAAACAAGCCATCTATTTTAAAGCTATCCAGGGCTTAACCTATATGAACTCTATTTATCATGTCTAATGCATGTGATTTAATGTAT
GTTTAATTTGATATCATGTTTTAAAATATCCTACTTCTGGTAGCCATTTAATTCCTCCCCCTACCCCCAAATAAATCAGGCATGCAGGAG
GCCTGATATTTAGTAATGTCATTGTGTTTGACCTTGAAGGAAAATGCTATTAGTCCGTCGTGCTTGATTTGTTTTTGTCCTTGAATAAGC
ATGTTATGTATATTGTCTCGTGTTTTTATTTTTACACCATATTGTATTACACTTTTAGTATTCACCAGCATAATCACTGTCTGCCTAAAA
TATGCAACTCTTTGCATTACAATATGAAGTAAAGTTCTATGAAGTATGCATTTTGTGTAACTAATGTAAAAACACAAATTTTATAAAATT
GTACAGTTTTTTAAAAACTACTCACAACTAGCAGATGGCTTAAATGTAGCAATCTCTGCGTTAATTAAATGCCTTTAAGAGATATAATTA
ACGTGCAGTTTTAATATCTACTAAATTAAGAATGACTTCATTATGATCATGATTTGCCACAATGTCCTTAACTCTAATGCCTGGACTGGC
CATGTTCTAGTCTGTTGCGCTGTTACAATCTGTATTGGTGCTAGTCAGAAAATTCCTAGCTCACATAGCCCAAAAGGGTGCGAGGGAGAG
GTGGATTACCAGTATTGTTCAATAATCCATGGTTCAAAGACTGTATAAATGCATTTTATTTTAAATAAAAGCAAAACTTTTATTTAATAT

>60382_60382_1_NRXN3-FERMT2_NRXN3_chr14_80271542_ENST00000281127_FERMT2_chr14_53348187_ENST00000341590_length(amino acids)=839AA_BP=334
MTMHLRIHARRSPPRRPAWTLGIWFLFWGCIVSSVWSSSNVASSSSTSSSPGSHSQHEHHFHGSKHHSVPISIYRSPVSLRGGHAGATYI
FGKSGGLILYTWPANDRPSTRSDRLAVGFSTTVKDGILVRIDSAPGLGDFLQLHIEQGKIGVVFNIGTVDISIKEERTPVNDGKYHVVRF
TRNGGNATLQVDNWPVNEHYPTGRQLTIFNTQAQIAIGGKDKGRLFQGQLSGLYYDGLKVLNMAAENNPNIKINGSVRLVGEVPSILGTT
QTTSMPPEMSTTVMETTTTMATTTTRKNRSTASIQPTSDDLVSSAECSSDDEDFVECEPSTGRSGSIYSSPGLYSKTMTPTYDAHDGSPL
SPTSAWFGDSALSEGNPGILAVSQPITSPEILAKMFKPQALLDKAKINQGWLDSSRSLMEQDVKENEALLLRFKYYSFFDLNPKYDAIRI
NQLYEQAKWAILLEEIECTEEEMMMFAALQYHINKLSIMTSENHLNNSDKEVDEVDAALSDLEITLEGGKTSTILGDITSIPELADYIKV
FKPKKLTLKGYKQYWCTFKDTSISCYKSKEESSGTPAHQMNLRGCEVTPDVNISGQKFNIKLLIPVAEGMNEIWLRCDNEKQYAHWMAAC
RLASKGKTMADSSYNLEVQNILSFLKMQHLNPDPQLIPEQITTDITPECLVSPRYLKKYKNKQITARILEAHQNVAQMSLIEAKMRFIQA
WQSLPEFGITHFIARFQGGKKEELIGIAYNRLIRMDASTGDAIKTWRFSNMKQWNVNWEIKMVTVEFADEVRLSFICTEVDCKVVHEFIG

--------------------------------------------------------------
>60382_60382_2_NRXN3-FERMT2_NRXN3_chr14_80271542_ENST00000281127_FERMT2_chr14_53348187_ENST00000343279_length(transcript)=4516nt_BP=1876nt
ACTTCGCAGGCGCCCGCCCGCCTCTCGGCCACCTCTGCAGCCTGCCAGGCACCTCCTCTTGCGCTCTCGCTGATTTCGCCCACCCACCTC
CCTCCACCCCGTGCCACGTTGGTTTGGGTGGCTGCTCCGCACCGGGTTCCTCCTCCTCTCCTCTTTCCCTCCAGTCCTTCTTATTCTCTT
CCTCTGGCTGCGGTGGCTGCTGCTGCTGCTGGTTTTCATCCAGTTGGGAAACCCAGGAAGCCGGCGGCTGCTCCGTGGCGCTAGTCCAGC
ACGCCCAGGGTTAAAAGCCTCGCGCCCTTCCGCGGAGACTCCCAGGAACACCCGAAGAACTCTTCCACCTGCAGCCCCCTTTTGCCTGGC
AGTTCTGCATTGCATCTCATGGAAGTGGAAACAGGAAAATAAAAATGTTCAAACTCCTTGGATGTTGGGATAAACTCACCTGAACCCACT
TGGGTTCGGGCTGCCTCCTTCTCTTCCTTCATTGCCACCTTTCCTCTGTGTGGCTCCCGGGAGTGTGCGGTTAAGTCATCAGACTCGAAG
TGCCTAGAGATCCGGAGGAAGCCGCGCCGGTCTTCCCCTGACATGCGTGGCATGCCGGGGCTCCGTAGGAGGTTTGCTATACCTGGGAGG
ACCCTGGCATTCTAAATTTCAGCTCCGGGAAAGAGAAGGGGCTTTTTGCCTTTTATCTTTTTTTTTTCTTTCTTTAAGTAGTAATTTTTT
AACTGATTCATTGTTTGGAAAGCGCATATTGCTTCCCTCTTCCCCGAATTCTGGCAACTCTTCCTCCTGCTATGATGGGCCCTTGGGCAT
CATGAACTTCATTACTCCTCACTGGCTGGAATTCAAACTGCCCATCTGTAGTGGTCCCGTGCGTTGACCATGCACCTGAGAATCCACGCG
AGACGGAGCCCTCCTCGCCGGCCGGCCTGGACGCTTGGGATCTGGTTCCTGTTCTGGGGATGTATCGTCAGCTCTGTATGGAGTTCTTCT
AATGTAGCTTCCTCCTCCTCCACCTCTTCCTCGCCGGGGTCTCACTCTCAGCACGAGCACCATTTCCATGGCAGCAAGCATCACTCAGTG
CCTATTTCTATCTATCGTTCCCCTGTTTCCCTTCGAGGAGGACACGCTGGCGCTACGTACATCTTTGGGAAAAGTGGTGGGCTTATCCTC
TACACCTGGCCAGCCAATGACAGGCCCAGCACGCGGTCTGACCGCCTTGCCGTGGGCTTCAGCACCACTGTGAAGGATGGCATCTTGGTC
CGCATCGACAGTGCTCCAGGACTTGGTGACTTCCTCCAGCTTCACATAGAACAGGGGAAAATTGGAGTTGTCTTCAACATTGGCACAGTT
GACATCTCCATCAAAGAGGAGAGAACCCCTGTAAATGACGGCAAATACCATGTGGTACGCTTCACCAGGAACGGCGGCAACGCCACCCTG
CAGGTGGACAACTGGCCAGTGAATGAACATTATCCTACAGGCCGGCAGTTAACCATCTTCAACACTCAGGCGCAAATAGCCATTGGTGGA
AAGGACAAAGGACGCCTCTTCCAAGGCCAACTCTCTGGGCTCTATTATGATGGTTTGAAAGTACTGAACATGGCGGCTGAGAACAACCCC
AATATTAAAATCAATGGAAGTGTTCGGCTGGTTGGAGAAGTCCCATCAATTTTGGGAACAACACAGACGACCTCCATGCCACCAGAAATG
TCTACTACTGTCATGGAAACCACTACTACAATGGCGACTACCACAACCCGTAAGAATCGCTCTACAGCCAGCATTCAGCCAACATCAGAT
GATCTTGTTTCATCTGCTGAATGTTCAAGTGATGATGAAGACTTTGTTGAATGTGAGCCGAGTACAGGTAGGTCAGGAAGTATATATTCA
AGCCCAGGACTGTATAGTAAAACAATGACCCCCACTTATGATGCTCATGATGGAAGCCCCTTGTCACCAACTTCTGCTTGGTTTGGTGAC
AGTGCTTTGTCAGAAGGCAATCCTGGTATACTTGCTGTCAGTCAACCAATCACGTCACCAGAAATCTTGGCAAAAATGTTCAAGCCTCAA
GCTCTTCTTGATAAAGCAAAAATCAACCAAGGATGGCTTGATTCCTCAAGATCTCTCATGGAACAAGATGTGAAGGAAAATGAGGCCTTG
CTGCTCCGATTCAAGTATTACAGCTTTTTTGATTTGAATCCAAAGTATGATGCAATCAGAATCAATCAGCTTTACGAGCAGGCCAAATGG
GCCATTCTCCTGGAAGAGATTGAATGCACAGAAGAAGAAATGATGATGTTTGCAGCCCTGCAGTATCATATCAATAAGCTGTCAATCATG
ACATCAGAGAATCATTTGAACAACAGTGACAAAGAAGTTGATGAAGTTGATGCTGCCCTTTCAGACCTGGAGATTACTCTGGAAGGGGGT
AAAACGTCAACAATTTTGGGTGACATTACTTCCATTCCTGAACTTGCTGACTACATTAAAGTTTTCAAGCCAAAAAAGCTGACTCTGAAA
GGTTACAAACAATATTGGTGCACCTTCAAAGACACATCCATTTCTTGTTATAAGAGCAAAGAAGAATCCAGTGGCACACCAGCTCATCAG
ATGAACCTCAGGGGATGTGAAGTTACCCCAGATGTAAACATTTCAGGCCAAAAATTTAACATTAAACTCCTGATTCCAGTTGCAGAAGGC
ATGAATGAAATCTGGCTTCGTTGTGACAATGAAAAACAGTATGCACACTGGATGGCAGCCTGCAGATTAGCCTCCAAAGGCAAGACCATG
GCGGACAGTTCTTACAACTTAGAAGTTCAGAATATTCTTTCCTTTCTGAAGATGCAGCATTTAAACCCAGATCCTCAGTTAATACCAGAG
CAGATCACGACTGATATAACTCCTGAATGTTTGGTGTCTCCCCGCTATCTAAAAAAGTATAAGAACAAGCAGCCAGGCTATATAAGAGAT
TTGATAACAGCGAGAATCTTGGAGGCCCATCAGAATGTAGCTCAGATGAGTCTAATTGAAGCCAAGATGAGATTTATTCAAGCTTGGCAG
TCACTACCTGAATTTGGCATCACTCACTTCATTGCAAGGTTCCAAGGGGGCAAAAAAGAAGAACTTATTGGAATTGCATACAACAGACTG
ATTCGGATGGATGCCAGCACTGGAGATGCAATTAAAACATGGCGTTTCAGCAACATGAAACAGTGGAATGTCAACTGGGAAATCAAAATG
GTCACCGTAGAGTTTGCAGATGAAGTACGATTGTCCTTCATTTGTACTGAAGTAGATTGCAAAGTGGTTCATGAATTCATTGGTGGCTAC
ATATTTCTCTCAACACGTGCAAAAGACCAAAACGAGAGTTTAGATGAAGAGATGTTCTACAAACTTACCAGTGGTTGGGTGTGAATAGGA
ATACTGTTTAATGAAACTCCACGGCCATAACAATATTTAACTTTAAAAGCTGTTTGTTATATGCTGCTTAATAAAGTAAGCTTGAAATTT
ATCATTTTATCATGAAAACTTCTTTGCCTTACCAGACCAGTTAATATGTGCACTAAACAAGCACGACTATTAATCTATCATGTTATGATA
TAATAAACTTGAATTTGTCACACATTCCTTAGGGCCATGAATTGAAAACTGAAATAGTGGGCAAATCAGGAACAAACCATCACTGATTTA
CTGATTTAAGCTAGCCAAACTGTAAGAAACAAGCCATCTATTTTAAAGCTATCCAGGGCTTAACCTATATGAACTCTATTTATCATGTCT
AATGCATGTGATTTAATGTATGTTTAATTTGATATCATGTTTTAAAATATCCTACTTCTGGTAGCCATTTAATTCCTCCCCCTACCCCCA
AATAAATCAGGCATGCAGGAGGCCTGATATTTAGTAATGTCATTGTGTTTGACCTTGAAGGAAAATGCTATTAGTCCGTCGTGCTTGATT
TGTTTTTGTCCTTGAATAAGCATGTTATGTATATTGTCTCGTGTTTTTATTTTTACACCATATTGTATTACACTTTTAGTATTCACCAGC
ATAATCACTGTCTGCCTAAAATATGCAACTCTTTGCATTACAATATGAAGTAAAGTTCTATGAAGTATGCATTTTGTGTAACTAATGTAA
AAACACAAATTTTATAAAATTGTACAGTTTTTTAAAAACTACTCACAACTAGCAGATGGCTTAAATGTAGCAATCTCTGCGTTAATTAAA
TGCCTTTAAGAGATATAATTAACGTGCAGTTTTAATATCTACTAAATTAAGAATGACTTCATTATGATCATGATTTGCCACAATGTCCTT
AACTCTAATGCCTGGACTGGCCATGTTCTAGTCTGTTGCGCTGTTACAATCTGTATTGGTGCTAGTCAGAAAATTCCTAGCTCACATAGC
CCAAAAGGGTGCGAGGGAGAGGTGGATTACCAGTATTGTTCAATAATCCATGGTTCAAAGACTGTATAAATGCATTTTATTTTAAATAAA

>60382_60382_2_NRXN3-FERMT2_NRXN3_chr14_80271542_ENST00000281127_FERMT2_chr14_53348187_ENST00000343279_length(amino acids)=846AA_BP=334
MTMHLRIHARRSPPRRPAWTLGIWFLFWGCIVSSVWSSSNVASSSSTSSSPGSHSQHEHHFHGSKHHSVPISIYRSPVSLRGGHAGATYI
FGKSGGLILYTWPANDRPSTRSDRLAVGFSTTVKDGILVRIDSAPGLGDFLQLHIEQGKIGVVFNIGTVDISIKEERTPVNDGKYHVVRF
TRNGGNATLQVDNWPVNEHYPTGRQLTIFNTQAQIAIGGKDKGRLFQGQLSGLYYDGLKVLNMAAENNPNIKINGSVRLVGEVPSILGTT
QTTSMPPEMSTTVMETTTTMATTTTRKNRSTASIQPTSDDLVSSAECSSDDEDFVECEPSTGRSGSIYSSPGLYSKTMTPTYDAHDGSPL
SPTSAWFGDSALSEGNPGILAVSQPITSPEILAKMFKPQALLDKAKINQGWLDSSRSLMEQDVKENEALLLRFKYYSFFDLNPKYDAIRI
NQLYEQAKWAILLEEIECTEEEMMMFAALQYHINKLSIMTSENHLNNSDKEVDEVDAALSDLEITLEGGKTSTILGDITSIPELADYIKV
FKPKKLTLKGYKQYWCTFKDTSISCYKSKEESSGTPAHQMNLRGCEVTPDVNISGQKFNIKLLIPVAEGMNEIWLRCDNEKQYAHWMAAC
RLASKGKTMADSSYNLEVQNILSFLKMQHLNPDPQLIPEQITTDITPECLVSPRYLKKYKNKQPGYIRDLITARILEAHQNVAQMSLIEA
KMRFIQAWQSLPEFGITHFIARFQGGKKEELIGIAYNRLIRMDASTGDAIKTWRFSNMKQWNVNWEIKMVTVEFADEVRLSFICTEVDCK

--------------------------------------------------------------
>60382_60382_3_NRXN3-FERMT2_NRXN3_chr14_80271542_ENST00000281127_FERMT2_chr14_53348187_ENST00000395631_length(transcript)=4502nt_BP=1876nt
ACTTCGCAGGCGCCCGCCCGCCTCTCGGCCACCTCTGCAGCCTGCCAGGCACCTCCTCTTGCGCTCTCGCTGATTTCGCCCACCCACCTC
CCTCCACCCCGTGCCACGTTGGTTTGGGTGGCTGCTCCGCACCGGGTTCCTCCTCCTCTCCTCTTTCCCTCCAGTCCTTCTTATTCTCTT
CCTCTGGCTGCGGTGGCTGCTGCTGCTGCTGGTTTTCATCCAGTTGGGAAACCCAGGAAGCCGGCGGCTGCTCCGTGGCGCTAGTCCAGC
ACGCCCAGGGTTAAAAGCCTCGCGCCCTTCCGCGGAGACTCCCAGGAACACCCGAAGAACTCTTCCACCTGCAGCCCCCTTTTGCCTGGC
AGTTCTGCATTGCATCTCATGGAAGTGGAAACAGGAAAATAAAAATGTTCAAACTCCTTGGATGTTGGGATAAACTCACCTGAACCCACT
TGGGTTCGGGCTGCCTCCTTCTCTTCCTTCATTGCCACCTTTCCTCTGTGTGGCTCCCGGGAGTGTGCGGTTAAGTCATCAGACTCGAAG
TGCCTAGAGATCCGGAGGAAGCCGCGCCGGTCTTCCCCTGACATGCGTGGCATGCCGGGGCTCCGTAGGAGGTTTGCTATACCTGGGAGG
ACCCTGGCATTCTAAATTTCAGCTCCGGGAAAGAGAAGGGGCTTTTTGCCTTTTATCTTTTTTTTTTCTTTCTTTAAGTAGTAATTTTTT
AACTGATTCATTGTTTGGAAAGCGCATATTGCTTCCCTCTTCCCCGAATTCTGGCAACTCTTCCTCCTGCTATGATGGGCCCTTGGGCAT
CATGAACTTCATTACTCCTCACTGGCTGGAATTCAAACTGCCCATCTGTAGTGGTCCCGTGCGTTGACCATGCACCTGAGAATCCACGCG
AGACGGAGCCCTCCTCGCCGGCCGGCCTGGACGCTTGGGATCTGGTTCCTGTTCTGGGGATGTATCGTCAGCTCTGTATGGAGTTCTTCT
AATGTAGCTTCCTCCTCCTCCACCTCTTCCTCGCCGGGGTCTCACTCTCAGCACGAGCACCATTTCCATGGCAGCAAGCATCACTCAGTG
CCTATTTCTATCTATCGTTCCCCTGTTTCCCTTCGAGGAGGACACGCTGGCGCTACGTACATCTTTGGGAAAAGTGGTGGGCTTATCCTC
TACACCTGGCCAGCCAATGACAGGCCCAGCACGCGGTCTGACCGCCTTGCCGTGGGCTTCAGCACCACTGTGAAGGATGGCATCTTGGTC
CGCATCGACAGTGCTCCAGGACTTGGTGACTTCCTCCAGCTTCACATAGAACAGGGGAAAATTGGAGTTGTCTTCAACATTGGCACAGTT
GACATCTCCATCAAAGAGGAGAGAACCCCTGTAAATGACGGCAAATACCATGTGGTACGCTTCACCAGGAACGGCGGCAACGCCACCCTG
CAGGTGGACAACTGGCCAGTGAATGAACATTATCCTACAGGCCGGCAGTTAACCATCTTCAACACTCAGGCGCAAATAGCCATTGGTGGA
AAGGACAAAGGACGCCTCTTCCAAGGCCAACTCTCTGGGCTCTATTATGATGGTTTGAAAGTACTGAACATGGCGGCTGAGAACAACCCC
AATATTAAAATCAATGGAAGTGTTCGGCTGGTTGGAGAAGTCCCATCAATTTTGGGAACAACACAGACGACCTCCATGCCACCAGAAATG
TCTACTACTGTCATGGAAACCACTACTACAATGGCGACTACCACAACCCGTAAGAATCGCTCTACAGCCAGCATTCAGCCAACATCAGAT
GATCTTGTTTCATCTGCTGAATGTTCAAGTGATGATGAAGACTTTGTTGAATGTGAGCCGAGTACAGGTAGGTCAGGAAGTATATATTCA
AGCCCAGGACTGTATAGTAAAACAATGACCCCCACTTATGATGCTCATGATGGAAGCCCCTTGTCACCAACTTCTGCTTGGTTTGGTGAC
AGTGCTTTGTCAGAAGGCAATCCTGGTATACTTGCTGTCAGTCAACCAATCACGTCACCAGAAATCTTGGCAAAAATGTTCAAGCCTCAA
GCTCTTCTTGATAAAGCAAAAATCAACCAAGGATGGCTTGATTCCTCAAGATCTCTCATGGAACAAGATGTGAAGGAAAATGAGGCCTTG
CTGCTCCGATTCAAGTATTACAGCTTTTTTGATTTGAATCCAAAGTATGATGCAATCAGAATCAATCAGCTTTACGAGCAGGCCAAATGG
GCCATTCTCCTGGAAGAGATTGAATGCACAGAAGAAGAAATGATGATGTTTGCAGCCCTGCAGTATCATATCAATAAGCTGTCAATCATG
ACATCAGAGAATCATTTGAACAACAGTGACAAAGAAGTTGATGAAGTTGATGCTGCCCTTTCAGACCTGGAGATTACTCTGGAAGGGGGT
AAAACGTCAACAATTTTGGGTGACATTACTTCCATTCCTGAACTTGCTGACTACATTAAAGTTTTCAAGCCAAAAAAGCTGACTCTGAAA
GGTTACAAACAATATTGGTGCACCTTCAAAGACACATCCATTTCTTGTTATAAGAGCAAAGAAGAATCCAGTGGCACACCAGCTCATCAG
ATGAACCTCAGGGGATGTGAAGTTACCCCAGATGTAAACATTTCAGGCCAAAAATTTAACATTAAACTCCTGATTCCAGTTGCAGAAGGC
ATGAATGAAATCTGGCTTCGTTGTGACAATGAAAAACAGTATGCACACTGGATGGCAGCCTGCAGATTAGCCTCCAAAGGCAAGACCATG
GCGGACAGTTCTTACAACTTAGAAGTTCAGAATATTCTTTCCTTTCTGAAGATGCAGCATTTAAACCCAGATCCTCAGTTAATACCAGAG
CAGATCACGACTGATATAACTCCTGAATGTTTGGTGTCTCCCCGCTATCTAAAAAAGTATAAGAACAAGCAGATAACAGCGAGAATCTTG
GAGGCCCATCAGAATGTAGCTCAGATGAGTCTAATTGAAGCCAAGATGAGATTTATTCAAGCTTGGCAGTCACTACCTGAATTTGGCATC
ACTCACTTCATTGCAAGGTTCCAAGGGGGCAAAAAAGAAGAACTTATTGGAATTGCATACAACAGACTGATTCGGATGGATGCCAGCACT
GGAGATGCAATTAAAACATGGCGTTTCAGCAACATGAAACAGTGGAATGTCAACTGGGAAATCAAAATGGTCACCGTAGAGTTTGCAGAT
GAAGTACGATTGTCCTTCATTTGTACTGAAGTAGATTGCAAAGTGGTTCATGAATTCATTGGTGGCTACATATTTCTCTCAACACGTGCA
AAAGACCAAAACGAGAGTTTAGATGAAGAGATGTTCTACAAACTTACCAGTGGTTGGGTGTGAATAGGAATACTGTTTAATGAAACTCCA
CGGCCATAACAATATTTAACTTTAAAAGCTGTTTGTTATATGCTGCTTAATAAAGTAAGCTTGAAATTTATCATTTTATCATGAAAACTT
CTTTGCCTTACCAGACCAGTTAATATGTGCACTAAACAAGCACGACTATTAATCTATCATGTTATGATATAATAAACTTGAATTTGTCAC
ACATTCCTTAGGGCCATGAATTGAAAACTGAAATAGTGGGCAAATCAGGAACAAACCATCACTGATTTACTGATTTAAGCTAGCCAAACT
GTAAGAAACAAGCCATCTATTTTAAAGCTATCCAGGGCTTAACCTATATGAACTCTATTTATCATGTCTAATGCATGTGATTTAATGTAT
GTTTAATTTGATATCATGTTTTAAAATATCCTACTTCTGGTAGCCATTTAATTCCTCCCCCTACCCCCAAATAAATCAGGCATGCAGGAG
GCCTGATATTTAGTAATGTCATTGTGTTTGACCTTGAAGGAAAATGCTATTAGTCCGTCGTGCTTGATTTGTTTTTGTCCTTGAATAAGC
ATGTTATGTATATTGTCTCGTGTTTTTATTTTTACACCATATTGTATTACACTTTTAGTATTCACCAGCATAATCACTGTCTGCCTAAAA
TATGCAACTCTTTGCATTACAATATGAAGTAAAGTTCTATGAAGTATGCATTTTGTGTAACTAATGTAAAAACACAAATTTTATAAAATT
GTACAGTTTTTTAAAAACTACTCACAACTAGCAGATGGCTTAAATGTAGCAATCTCTGCGTTAATTAAATGCCTTTAAGAGATATAATTA
ACGTGCAGTTTTAATATCTACTAAATTAAGAATGACTTCATTATGATCATGATTTGCCACAATGTCCTTAACTCTAATGCCTGGACTGGC
CATGTTCTAGTCTGTTGCGCTGTTACAATCTGTATTGGTGCTAGTCAGAAAATTCCTAGCTCACATAGCCCAAAAGGGTGCGAGGGAGAG
GTGGATTACCAGTATTGTTCAATAATCCATGGTTCAAAGACTGTATAAATGCATTTTATTTTAAATAAAAGCAAAACTTTTATTTAATAT

>60382_60382_3_NRXN3-FERMT2_NRXN3_chr14_80271542_ENST00000281127_FERMT2_chr14_53348187_ENST00000395631_length(amino acids)=839AA_BP=334
MTMHLRIHARRSPPRRPAWTLGIWFLFWGCIVSSVWSSSNVASSSSTSSSPGSHSQHEHHFHGSKHHSVPISIYRSPVSLRGGHAGATYI
FGKSGGLILYTWPANDRPSTRSDRLAVGFSTTVKDGILVRIDSAPGLGDFLQLHIEQGKIGVVFNIGTVDISIKEERTPVNDGKYHVVRF
TRNGGNATLQVDNWPVNEHYPTGRQLTIFNTQAQIAIGGKDKGRLFQGQLSGLYYDGLKVLNMAAENNPNIKINGSVRLVGEVPSILGTT
QTTSMPPEMSTTVMETTTTMATTTTRKNRSTASIQPTSDDLVSSAECSSDDEDFVECEPSTGRSGSIYSSPGLYSKTMTPTYDAHDGSPL
SPTSAWFGDSALSEGNPGILAVSQPITSPEILAKMFKPQALLDKAKINQGWLDSSRSLMEQDVKENEALLLRFKYYSFFDLNPKYDAIRI
NQLYEQAKWAILLEEIECTEEEMMMFAALQYHINKLSIMTSENHLNNSDKEVDEVDAALSDLEITLEGGKTSTILGDITSIPELADYIKV
FKPKKLTLKGYKQYWCTFKDTSISCYKSKEESSGTPAHQMNLRGCEVTPDVNISGQKFNIKLLIPVAEGMNEIWLRCDNEKQYAHWMAAC
RLASKGKTMADSSYNLEVQNILSFLKMQHLNPDPQLIPEQITTDITPECLVSPRYLKKYKNKQITARILEAHQNVAQMSLIEAKMRFIQA
WQSLPEFGITHFIARFQGGKKEELIGIAYNRLIRMDASTGDAIKTWRFSNMKQWNVNWEIKMVTVEFADEVRLSFICTEVDCKVVHEFIG

--------------------------------------------------------------
>60382_60382_4_NRXN3-FERMT2_NRXN3_chr14_80271542_ENST00000281127_FERMT2_chr14_53348187_ENST00000399304_length(transcript)=3325nt_BP=1876nt
ACTTCGCAGGCGCCCGCCCGCCTCTCGGCCACCTCTGCAGCCTGCCAGGCACCTCCTCTTGCGCTCTCGCTGATTTCGCCCACCCACCTC
CCTCCACCCCGTGCCACGTTGGTTTGGGTGGCTGCTCCGCACCGGGTTCCTCCTCCTCTCCTCTTTCCCTCCAGTCCTTCTTATTCTCTT
CCTCTGGCTGCGGTGGCTGCTGCTGCTGCTGGTTTTCATCCAGTTGGGAAACCCAGGAAGCCGGCGGCTGCTCCGTGGCGCTAGTCCAGC
ACGCCCAGGGTTAAAAGCCTCGCGCCCTTCCGCGGAGACTCCCAGGAACACCCGAAGAACTCTTCCACCTGCAGCCCCCTTTTGCCTGGC
AGTTCTGCATTGCATCTCATGGAAGTGGAAACAGGAAAATAAAAATGTTCAAACTCCTTGGATGTTGGGATAAACTCACCTGAACCCACT
TGGGTTCGGGCTGCCTCCTTCTCTTCCTTCATTGCCACCTTTCCTCTGTGTGGCTCCCGGGAGTGTGCGGTTAAGTCATCAGACTCGAAG
TGCCTAGAGATCCGGAGGAAGCCGCGCCGGTCTTCCCCTGACATGCGTGGCATGCCGGGGCTCCGTAGGAGGTTTGCTATACCTGGGAGG
ACCCTGGCATTCTAAATTTCAGCTCCGGGAAAGAGAAGGGGCTTTTTGCCTTTTATCTTTTTTTTTTCTTTCTTTAAGTAGTAATTTTTT
AACTGATTCATTGTTTGGAAAGCGCATATTGCTTCCCTCTTCCCCGAATTCTGGCAACTCTTCCTCCTGCTATGATGGGCCCTTGGGCAT
CATGAACTTCATTACTCCTCACTGGCTGGAATTCAAACTGCCCATCTGTAGTGGTCCCGTGCGTTGACCATGCACCTGAGAATCCACGCG
AGACGGAGCCCTCCTCGCCGGCCGGCCTGGACGCTTGGGATCTGGTTCCTGTTCTGGGGATGTATCGTCAGCTCTGTATGGAGTTCTTCT
AATGTAGCTTCCTCCTCCTCCACCTCTTCCTCGCCGGGGTCTCACTCTCAGCACGAGCACCATTTCCATGGCAGCAAGCATCACTCAGTG
CCTATTTCTATCTATCGTTCCCCTGTTTCCCTTCGAGGAGGACACGCTGGCGCTACGTACATCTTTGGGAAAAGTGGTGGGCTTATCCTC
TACACCTGGCCAGCCAATGACAGGCCCAGCACGCGGTCTGACCGCCTTGCCGTGGGCTTCAGCACCACTGTGAAGGATGGCATCTTGGTC
CGCATCGACAGTGCTCCAGGACTTGGTGACTTCCTCCAGCTTCACATAGAACAGGGGAAAATTGGAGTTGTCTTCAACATTGGCACAGTT
GACATCTCCATCAAAGAGGAGAGAACCCCTGTAAATGACGGCAAATACCATGTGGTACGCTTCACCAGGAACGGCGGCAACGCCACCCTG
CAGGTGGACAACTGGCCAGTGAATGAACATTATCCTACAGGCCGGCAGTTAACCATCTTCAACACTCAGGCGCAAATAGCCATTGGTGGA
AAGGACAAAGGACGCCTCTTCCAAGGCCAACTCTCTGGGCTCTATTATGATGGTTTGAAAGTACTGAACATGGCGGCTGAGAACAACCCC
AATATTAAAATCAATGGAAGTGTTCGGCTGGTTGGAGAAGTCCCATCAATTTTGGGAACAACACAGACGACCTCCATGCCACCAGAAATG
TCTACTACTGTCATGGAAACCACTACTACAATGGCGACTACCACAACCCGTAAGAATCGCTCTACAGCCAGCATTCAGCCAACATCAGAT
GATCTTGTTTCATCTGCTGAATGTTCAAGTGATGATGAAGACTTTGTTGAATGTGAGCCGAGTACAGGTAGGTCAGGAAGTATATATTCA
AGCCCAGGACTGTATAGTAAAACAATGACCCCCACTTATGATGCTCATGATGGAAGCCCCTTGTCACCAACTTCTGCTTGGTTTGGTGAC
AGTGCTTTGTCAGAAGGCAATCCTGGTATACTTGCTGTCAGTCAACCAATCACGTCACCAGAAATCTTGGCAAAAATGTTCAAGCCTCAA
GCTCTTCTTGATAAAGCAAAAATCAACCAAGGATGGCTTGATTCCTCAAGATCTCTCATGGAACAAGATGTGAAGGAAAATGAGGCCTTG
CTGCTCCGATTCAAGTATTACAGCTTTTTTGATTTGAATCCAAAGTATGATGCAATCAGAATCAATCAGCTTTACGAGCAGGCCAAATGG
GCCATTCTCCTGGAAGAGATTGAATGCACAGAAGAAGAAATGATGATGTTTGCAGCCCTGCAGTATCATATCAATAAGCTGTCAATCATG
ACATCAGAGAATCATTTGAACAACAGTGACAAAGAAGTTGATGAAGTTGATGCTGCCCTTTCAGACCTGGAGATTACTCTGGAAGGGGGT
AAAACGTCAACAATTTTGGGTGACATTACTTCCATTCCTGAACTTGCTGACTACATTAAAGTTTTCAAGCCAAAAAAGCTGACTCTGAAA
GGTTACAAACAATATTGGTGCACCTTCAAAGACACATCCATTTCTTGTTATAAGAGCAAAGAAGAATCCAGTGGCACACCAGCTCATCAG
ATGAACCTCAGGGGATGTGAAGTTACCCCAGATGTAAACATTTCAGGCCAAAAATTTAACATTAAACTCCTGATTCCAGTTGCAGAAGGC
ATGAATGAAATCTGGCTTCGTTGTGACAATGAAAAACAGTATGCACACTGGATGGCAGCCTGCAGATTAGCCTCCAAAGGCAAGACCATG
GCGGACAGTTCTTACAACTTAGAAGTTCAGAATATTCTTTCCTTTCTGAAGATGCAGCATTTAAACCCAGATCCTCAGTTAATACCAGAG
CAGATCACGACTGATATAACTCCTGAATGTTTGGTGTCTCCCCGCTATCTAAAAAAGTATAAGAACAAGCAGCCAGGCTATATAAGAGAT
TTGATAACAGCGAGAATCTTGGAGGCCCATCAGAATGTAGCTCAGATGAGTCTAATTGAAGCCAAGATGAGATTTATTCAAGCTTGGCAG
TCACTACCTGAATTTGGCATCACTCACTTCATTGCAAGGTTCCAAGGGGGCAAAAAAGAAGAACTTATTGGAATTGCATACAACAGACTG
ATTCGGATGGATGCCAGCACTGGAGATGCAATTAAAACATGGCGTTTCAGCAACATGAAACAGTGGAATGTCAACTGGGAAATCAAAATG

>60382_60382_4_NRXN3-FERMT2_NRXN3_chr14_80271542_ENST00000281127_FERMT2_chr14_53348187_ENST00000399304_length(amino acids)=792AA_BP=334
MTMHLRIHARRSPPRRPAWTLGIWFLFWGCIVSSVWSSSNVASSSSTSSSPGSHSQHEHHFHGSKHHSVPISIYRSPVSLRGGHAGATYI
FGKSGGLILYTWPANDRPSTRSDRLAVGFSTTVKDGILVRIDSAPGLGDFLQLHIEQGKIGVVFNIGTVDISIKEERTPVNDGKYHVVRF
TRNGGNATLQVDNWPVNEHYPTGRQLTIFNTQAQIAIGGKDKGRLFQGQLSGLYYDGLKVLNMAAENNPNIKINGSVRLVGEVPSILGTT
QTTSMPPEMSTTVMETTTTMATTTTRKNRSTASIQPTSDDLVSSAECSSDDEDFVECEPSTGRSGSIYSSPGLYSKTMTPTYDAHDGSPL
SPTSAWFGDSALSEGNPGILAVSQPITSPEILAKMFKPQALLDKAKINQGWLDSSRSLMEQDVKENEALLLRFKYYSFFDLNPKYDAIRI
NQLYEQAKWAILLEEIECTEEEMMMFAALQYHINKLSIMTSENHLNNSDKEVDEVDAALSDLEITLEGGKTSTILGDITSIPELADYIKV
FKPKKLTLKGYKQYWCTFKDTSISCYKSKEESSGTPAHQMNLRGCEVTPDVNISGQKFNIKLLIPVAEGMNEIWLRCDNEKQYAHWMAAC
RLASKGKTMADSSYNLEVQNILSFLKMQHLNPDPQLIPEQITTDITPECLVSPRYLKKYKNKQPGYIRDLITARILEAHQNVAQMSLIEA

--------------------------------------------------------------
>60382_60382_5_NRXN3-FERMT2_NRXN3_chr14_80271542_ENST00000281127_FERMT2_chr14_53348187_ENST00000553373_length(transcript)=3414nt_BP=1876nt
ACTTCGCAGGCGCCCGCCCGCCTCTCGGCCACCTCTGCAGCCTGCCAGGCACCTCCTCTTGCGCTCTCGCTGATTTCGCCCACCCACCTC
CCTCCACCCCGTGCCACGTTGGTTTGGGTGGCTGCTCCGCACCGGGTTCCTCCTCCTCTCCTCTTTCCCTCCAGTCCTTCTTATTCTCTT
CCTCTGGCTGCGGTGGCTGCTGCTGCTGCTGGTTTTCATCCAGTTGGGAAACCCAGGAAGCCGGCGGCTGCTCCGTGGCGCTAGTCCAGC
ACGCCCAGGGTTAAAAGCCTCGCGCCCTTCCGCGGAGACTCCCAGGAACACCCGAAGAACTCTTCCACCTGCAGCCCCCTTTTGCCTGGC
AGTTCTGCATTGCATCTCATGGAAGTGGAAACAGGAAAATAAAAATGTTCAAACTCCTTGGATGTTGGGATAAACTCACCTGAACCCACT
TGGGTTCGGGCTGCCTCCTTCTCTTCCTTCATTGCCACCTTTCCTCTGTGTGGCTCCCGGGAGTGTGCGGTTAAGTCATCAGACTCGAAG
TGCCTAGAGATCCGGAGGAAGCCGCGCCGGTCTTCCCCTGACATGCGTGGCATGCCGGGGCTCCGTAGGAGGTTTGCTATACCTGGGAGG
ACCCTGGCATTCTAAATTTCAGCTCCGGGAAAGAGAAGGGGCTTTTTGCCTTTTATCTTTTTTTTTTCTTTCTTTAAGTAGTAATTTTTT
AACTGATTCATTGTTTGGAAAGCGCATATTGCTTCCCTCTTCCCCGAATTCTGGCAACTCTTCCTCCTGCTATGATGGGCCCTTGGGCAT
CATGAACTTCATTACTCCTCACTGGCTGGAATTCAAACTGCCCATCTGTAGTGGTCCCGTGCGTTGACCATGCACCTGAGAATCCACGCG
AGACGGAGCCCTCCTCGCCGGCCGGCCTGGACGCTTGGGATCTGGTTCCTGTTCTGGGGATGTATCGTCAGCTCTGTATGGAGTTCTTCT
AATGTAGCTTCCTCCTCCTCCACCTCTTCCTCGCCGGGGTCTCACTCTCAGCACGAGCACCATTTCCATGGCAGCAAGCATCACTCAGTG
CCTATTTCTATCTATCGTTCCCCTGTTTCCCTTCGAGGAGGACACGCTGGCGCTACGTACATCTTTGGGAAAAGTGGTGGGCTTATCCTC
TACACCTGGCCAGCCAATGACAGGCCCAGCACGCGGTCTGACCGCCTTGCCGTGGGCTTCAGCACCACTGTGAAGGATGGCATCTTGGTC
CGCATCGACAGTGCTCCAGGACTTGGTGACTTCCTCCAGCTTCACATAGAACAGGGGAAAATTGGAGTTGTCTTCAACATTGGCACAGTT
GACATCTCCATCAAAGAGGAGAGAACCCCTGTAAATGACGGCAAATACCATGTGGTACGCTTCACCAGGAACGGCGGCAACGCCACCCTG
CAGGTGGACAACTGGCCAGTGAATGAACATTATCCTACAGGCCGGCAGTTAACCATCTTCAACACTCAGGCGCAAATAGCCATTGGTGGA
AAGGACAAAGGACGCCTCTTCCAAGGCCAACTCTCTGGGCTCTATTATGATGGTTTGAAAGTACTGAACATGGCGGCTGAGAACAACCCC
AATATTAAAATCAATGGAAGTGTTCGGCTGGTTGGAGAAGTCCCATCAATTTTGGGAACAACACAGACGACCTCCATGCCACCAGAAATG
TCTACTACTGTCATGGAAACCACTACTACAATGGCGACTACCACAACCCGTAAGAATCGCTCTACAGCCAGCATTCAGCCAACATCAGAT
GATCTTGTTTCATCTGCTGAATGTTCAAGTGATGATGAAGACTTTGTTGAATGTGAGCCGAGTACAGGTAGGTCAGGAAGTATATATTCA
AGCCCAGGACTGTATAGTAAAACAATGACCCCCACTTATGATGCTCATGATGGAAGCCCCTTGTCACCAACTTCTGCTTGGTTTGGTGAC
AGTGCTTTGTCAGAAGGCAATCCTGGTATACTTGCTGTCAGTCAACCAATCACGTCACCAGAAATCTTGGCAAAAATGTTCAAGCCTCAA
GCTCTTCTTGATAAAGCAAAAATCAACCAAGGATGGCTTGATTCCTCAAGATCTCTCATGGAACAAGATGTGAAGGAAAATGAGGCCTTG
CTGCTCCGATTCAAGTATTACAGCTTTTTTGATTTGAATCCAAAGTATGATGCAATCAGAATCAATCAGCTTTACGAGCAGGCCAAATGG
GCCATTCTCCTGGAAGAGATTGAATGCACAGAAGAAGAAATGATGATGTTTGCAGCCCTGCAGTATCATATCAATAAGCTGTCAATCATG
ACATCAGAGAATCATTTGAACAACAGTGACAAAGAAGTTGATGAAGTTGATGCTGCCCTTTCAGACCTGGAGATTACTCTGGAAGGGGGT
AAAACGTCAACAATTTTGGGTGACATTACTTCCATTCCTGAACTTGCTGACTACATTAAAGTTTTCAAGCCAAAAAAGCTGACTCTGAAA
GGTTACAAACAATATTGGTGCACCTTCAAAGACACATCCATTTCTTGTTATAAGAGCAAAGAAGAATCCAGTGGCACACCAGCTCATCAG
ATGAACCTCAGGGGATGTGAAGTTACCCCAGATGTAAACATTTCAGGCCAAAAATTTAACATTAAACTCCTGATTCCAGTTGCAGAAGGC
ATGAATGAAATCTGGCTTCGTTGTGACAATGAAAAACAGTATGCACACTGGATGGCAGCCTGCAGATTAGCCTCCAAAGGCAAGACCATG
GCGGACAGTTCTTACAACTTAGAAGTTCAGAATATTCTTTCCTTTCTGAAGATGCAGCATTTAAACCCAGATCCTCAGTTAATACCAGAG
CAGATCACGACTGATATAACTCCTGAATGTTTGGTGTCTCCCCGCTATCTAAAAAAGTATAAGAACAAGCAGCCAGGCTATATAAGAGAT
TTGATAACAGCGAGAATCTTGGAGGCCCATCAGAATGTAGCTCAGATGAGTCTAATTGAAGCCAAGATGAGATTTATTCAAGCTTGGCAG
TCACTACCTGAATTTGGCATCACTCACTTCATTGCAAGGTTCCAAGGGGGCAAAAAAGAAGAACTTATTGGAATTGCATACAACAGACTG
ATTCGGATGGATGCCAGCACTGGAGATGCAATTAAAACATGGCGTTTCAGCAACATGAAACAGTGGAATGTCAACTGGGAAATCAAAATG
GTCACCGTAGAGTTTGCAGATGAAGTACGATTGTCCTTCATTTGTACTGAAGTAGATTGCAAAGTGGTTCATGAATTCATTGGTGGCTAC

>60382_60382_5_NRXN3-FERMT2_NRXN3_chr14_80271542_ENST00000281127_FERMT2_chr14_53348187_ENST00000553373_length(amino acids)=846AA_BP=334
MTMHLRIHARRSPPRRPAWTLGIWFLFWGCIVSSVWSSSNVASSSSTSSSPGSHSQHEHHFHGSKHHSVPISIYRSPVSLRGGHAGATYI
FGKSGGLILYTWPANDRPSTRSDRLAVGFSTTVKDGILVRIDSAPGLGDFLQLHIEQGKIGVVFNIGTVDISIKEERTPVNDGKYHVVRF
TRNGGNATLQVDNWPVNEHYPTGRQLTIFNTQAQIAIGGKDKGRLFQGQLSGLYYDGLKVLNMAAENNPNIKINGSVRLVGEVPSILGTT
QTTSMPPEMSTTVMETTTTMATTTTRKNRSTASIQPTSDDLVSSAECSSDDEDFVECEPSTGRSGSIYSSPGLYSKTMTPTYDAHDGSPL
SPTSAWFGDSALSEGNPGILAVSQPITSPEILAKMFKPQALLDKAKINQGWLDSSRSLMEQDVKENEALLLRFKYYSFFDLNPKYDAIRI
NQLYEQAKWAILLEEIECTEEEMMMFAALQYHINKLSIMTSENHLNNSDKEVDEVDAALSDLEITLEGGKTSTILGDITSIPELADYIKV
FKPKKLTLKGYKQYWCTFKDTSISCYKSKEESSGTPAHQMNLRGCEVTPDVNISGQKFNIKLLIPVAEGMNEIWLRCDNEKQYAHWMAAC
RLASKGKTMADSSYNLEVQNILSFLKMQHLNPDPQLIPEQITTDITPECLVSPRYLKKYKNKQPGYIRDLITARILEAHQNVAQMSLIEA
KMRFIQAWQSLPEFGITHFIARFQGGKKEELIGIAYNRLIRMDASTGDAIKTWRFSNMKQWNVNWEIKMVTVEFADEVRLSFICTEVDCK

--------------------------------------------------------------

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Fusion Gene PPI Analysis for NRXN3-FERMT2


check button Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in

ChiPPI page.


check button Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160)
HgeneHgene's interactorsTgeneTgene's interactors


check button - Retained PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenStill interaction with


check button - Lost PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with
TgeneFERMT2chr14:80271542chr14:53348187ENST0000034159031540_81175.33333333333334681.0membranes containing phosphatidylinositol phosphate
TgeneFERMT2chr14:80271542chr14:53348187ENST0000034327931640_81175.33333333333334688.0membranes containing phosphatidylinositol phosphate
TgeneFERMT2chr14:80271542chr14:53348187ENST0000039563131540_81175.33333333333334681.0membranes containing phosphatidylinositol phosphate
TgeneFERMT2chr14:80271542chr14:53348187ENST0000039930431540_81175.33333333333334634.0membranes containing phosphatidylinositol phosphate
TgeneFERMT2chr14:80271542chr14:53348187ENST0000055337321540_81175.33333333333334688.0membranes containing phosphatidylinositol phosphate


check button - Retained PPIs, but lost function due to frame-shift fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


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Related Drugs for NRXN3-FERMT2


check button Drugs targeting genes involved in this fusion gene.
(DrugBank Version 5.1.8 2021-05-08)
PartnerGeneUniProtAccDrugBank IDDrug nameDrug activityDrug typeDrug status

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Related Diseases for NRXN3-FERMT2


check button Diseases associated with fusion partners.
(DisGeNet 4.0)
PartnerGeneDisease IDDisease name# pubmedsSource