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Center for Computational Systems Medicine
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Fusion Gene Summary

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Fusion Gene ORF analysis

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Fusion Genomic Features

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Fusion Protein Features

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Fusion Gene Sequence

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Fusion Gene PPI analysis

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Related Drugs

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Related Diseases

Fusion gene:NSD1-DPEP2 (FusionGDB2 ID:60416)

Fusion Gene Summary for NSD1-DPEP2

check button Fusion gene summary
Fusion gene informationFusion gene name: NSD1-DPEP2
Fusion gene ID: 60416
HgeneTgene
Gene symbol

NSD1

DPEP2

Gene ID

64324

64174

Gene namenuclear receptor binding SET domain protein 1dipeptidase 2
SynonymsARA267|KMT3B|SOTOS|SOTOS1|STOMBD2
Cytomap

5q35.3

16q22.1

Type of geneprotein-codingprotein-coding
Descriptionhistone-lysine N-methyltransferase, H3 lysine-36 and H4 lysine-20 specificH3-K36-HMTaseH4-K20-HMTaseNR-binding SET domain-containing proteinandrogen receptor coactivator 267 kDa proteinandrogen receptor-associated coregulator 267androgen receptor-asdipeptidase 2
Modification date2020032120200313
UniProtAcc..
Ensembl transtripts involved in fusion geneENST00000347982, ENST00000354179, 
ENST00000439151, ENST00000361032, 
ENST00000511258, 		ENST00000393847, 
ENST00000412757, ENST00000572888, 
Fusion gene scores* DoF score23 X 14 X 17=54742 X 4 X 2=16
# samples 372
** MAII scorelog2(37/5474*10)=-3.88699825884864
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0		log2(2/16*10)=0.321928094887362
effective Gene in Pan-Cancer Fusion Genes (eGinPCFGs).
DoF>8 and MAII>0
Context

PubMed: NSD1 [Title/Abstract] AND DPEP2 [Title/Abstract] AND fusion [Title/Abstract]

Most frequent breakpointNSD1(176619020)-DPEP2(68023301), # samples:3
Anticipated loss of major functional domain due to fusion event.NSD1-DPEP2 seems lost the major protein functional domain in Hgene partner, which is a CGC due to the frame-shifted ORF.
NSD1-DPEP2 seems lost the major protein functional domain in Hgene partner, which is a epigenetic factor due to the frame-shifted ORF.
NSD1-DPEP2 seems lost the major protein functional domain in Hgene partner, which is a essential gene due to the frame-shifted ORF.
NSD1-DPEP2 seems lost the major protein functional domain in Hgene partner, which is a IUPHAR drug target due to the frame-shifted ORF.
NSD1-DPEP2 seems lost the major protein functional domain in Tgene partner, which is a IUPHAR drug target due to the frame-shifted ORF.
* DoF score (Degree of Frequency) = # partners X # break points X # cancer types
** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)

check button Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez
PartnerGeneGO IDGO termPubMed ID
HgeneNSD1

GO:0045893

positive regulation of transcription, DNA-templated

11509567


check buttonFusion gene breakpoints across NSD1 (5'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check buttonFusion gene breakpoints across DPEP2 (3'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check button Fusion gene information from two resources (ChiTars 5.0 and ChimerDB 4.0)
* All genome coordinats were lifted-over on hg19.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
SourceDiseaseSampleHgeneHchrHbpHstrandTgeneTchrTbpTstrand
ChimerDB4CESCTCGA-C5-A7UH-01ANSD1chr5

176619020

-DPEP2chr16

68023301

-
ChimerDB4CESCTCGA-C5-A7UH-01ANSD1chr5

176619020

+DPEP2chr16

68023301

-
ChimerDB4CESCTCGA-C5-A7UH-01ANSD1chr5

176619020

+DPEP2chr16

68024900

-
ChimerDB4CESCTCGA-C5-A7UH-01ANSD1chr5

176619020

+DPEP2chr16

68027160

-


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Fusion Gene ORF analysis for NSD1-DPEP2

check button Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
ORFHenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrand
5CDS-5UTRENST00000347982ENST00000393847NSD1chr5

176619020

+DPEP2chr16

68027160

-
5CDS-5UTRENST00000347982ENST00000412757NSD1chr5

176619020

+DPEP2chr16

68027160

-
5CDS-5UTRENST00000347982ENST00000572888NSD1chr5

176619020

+DPEP2chr16

68027160

-
5CDS-5UTRENST00000354179ENST00000393847NSD1chr5

176619020

+DPEP2chr16

68027160

-
5CDS-5UTRENST00000354179ENST00000412757NSD1chr5

176619020

+DPEP2chr16

68027160

-
5CDS-5UTRENST00000354179ENST00000572888NSD1chr5

176619020

+DPEP2chr16

68027160

-
5CDS-5UTRENST00000439151ENST00000393847NSD1chr5

176619020

+DPEP2chr16

68027160

-
5CDS-5UTRENST00000439151ENST00000412757NSD1chr5

176619020

+DPEP2chr16

68027160

-
5CDS-5UTRENST00000439151ENST00000572888NSD1chr5

176619020

+DPEP2chr16

68027160

-
Frame-shiftENST00000347982ENST00000393847NSD1chr5

176619020

+DPEP2chr16

68024900

-
Frame-shiftENST00000347982ENST00000412757NSD1chr5

176619020

+DPEP2chr16

68024900

-
Frame-shiftENST00000347982ENST00000572888NSD1chr5

176619020

+DPEP2chr16

68024900

-
Frame-shiftENST00000354179ENST00000393847NSD1chr5

176619020

+DPEP2chr16

68024900

-
Frame-shiftENST00000354179ENST00000412757NSD1chr5

176619020

+DPEP2chr16

68024900

-
Frame-shiftENST00000354179ENST00000572888NSD1chr5

176619020

+DPEP2chr16

68024900

-
Frame-shiftENST00000439151ENST00000393847NSD1chr5

176619020

+DPEP2chr16

68024900

-
Frame-shiftENST00000439151ENST00000412757NSD1chr5

176619020

+DPEP2chr16

68024900

-
Frame-shiftENST00000439151ENST00000572888NSD1chr5

176619020

+DPEP2chr16

68024900

-
In-frameENST00000347982ENST00000393847NSD1chr5

176619020

+DPEP2chr16

68023301

-
In-frameENST00000347982ENST00000412757NSD1chr5

176619020

+DPEP2chr16

68023301

-
In-frameENST00000347982ENST00000572888NSD1chr5

176619020

+DPEP2chr16

68023301

-
In-frameENST00000354179ENST00000393847NSD1chr5

176619020

+DPEP2chr16

68023301

-
In-frameENST00000354179ENST00000412757NSD1chr5

176619020

+DPEP2chr16

68023301

-
In-frameENST00000354179ENST00000572888NSD1chr5

176619020

+DPEP2chr16

68023301

-
In-frameENST00000439151ENST00000393847NSD1chr5

176619020

+DPEP2chr16

68023301

-
In-frameENST00000439151ENST00000412757NSD1chr5

176619020

+DPEP2chr16

68023301

-
In-frameENST00000439151ENST00000572888NSD1chr5

176619020

+DPEP2chr16

68023301

-
intron-3CDSENST00000361032ENST00000393847NSD1chr5

176619020

+DPEP2chr16

68023301

-
intron-3CDSENST00000361032ENST00000393847NSD1chr5

176619020

+DPEP2chr16

68024900

-
intron-3CDSENST00000361032ENST00000412757NSD1chr5

176619020

+DPEP2chr16

68023301

-
intron-3CDSENST00000361032ENST00000412757NSD1chr5

176619020

+DPEP2chr16

68024900

-
intron-3CDSENST00000361032ENST00000572888NSD1chr5

176619020

+DPEP2chr16

68023301

-
intron-3CDSENST00000361032ENST00000572888NSD1chr5

176619020

+DPEP2chr16

68024900

-
intron-3CDSENST00000511258ENST00000393847NSD1chr5

176619020

+DPEP2chr16

68023301

-
intron-3CDSENST00000511258ENST00000393847NSD1chr5

176619020

+DPEP2chr16

68024900

-
intron-3CDSENST00000511258ENST00000412757NSD1chr5

176619020

+DPEP2chr16

68023301

-
intron-3CDSENST00000511258ENST00000412757NSD1chr5

176619020

+DPEP2chr16

68024900

-
intron-3CDSENST00000511258ENST00000572888NSD1chr5

176619020

+DPEP2chr16

68023301

-
intron-3CDSENST00000511258ENST00000572888NSD1chr5

176619020

+DPEP2chr16

68024900

-
intron-5UTRENST00000361032ENST00000393847NSD1chr5

176619020

+DPEP2chr16

68027160

-
intron-5UTRENST00000361032ENST00000412757NSD1chr5

176619020

+DPEP2chr16

68027160

-
intron-5UTRENST00000361032ENST00000572888NSD1chr5

176619020

+DPEP2chr16

68027160

-
intron-5UTRENST00000511258ENST00000393847NSD1chr5

176619020

+DPEP2chr16

68027160

-
intron-5UTRENST00000511258ENST00000412757NSD1chr5

176619020

+DPEP2chr16

68027160

-
intron-5UTRENST00000511258ENST00000572888NSD1chr5

176619020

+DPEP2chr16

68027160

-

check buttonORFfinder result based on the fusion transcript sequence of in-frame fusion genes.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandSeq length
(transcript)		BP loci
(transcript)		Predicted start
(transcript)		Predicted stop
(transcript)		Seq length
(amino acids)
ENST00000354179NSD1chr5176619020+ENST00000393847DPEP2chr1668023301-995416160882240
ENST00000354179NSD1chr5176619020+ENST00000412757DPEP2chr1668023301-992416160882240
ENST00000354179NSD1chr5176619020+ENST00000572888DPEP2chr1668023301-883416160882241
ENST00000439151NSD1chr5176619020+ENST00000393847DPEP2chr1668023301-16871108451574509
ENST00000439151NSD1chr5176619020+ENST00000412757DPEP2chr1668023301-16841108451574509
ENST00000439151NSD1chr5176619020+ENST00000572888DPEP2chr1668023301-15751108451574509
ENST00000347982NSD1chr5176619020+ENST00000393847DPEP2chr1668023301-936357101823240
ENST00000347982NSD1chr5176619020+ENST00000412757DPEP2chr1668023301-933357101823240
ENST00000347982NSD1chr5176619020+ENST00000572888DPEP2chr1668023301-824357101823241

check buttonDeepORF prediction of the coding potential based on the fusion transcript sequence of in-frame fusion genes. DeepORF is a coding potential classifier based on convolutional neural network by comparing the real Ribo-seq data. If the no-coding score < 0.5 and coding score > 0.5, then the in-frame fusion transcript is predicted as being likely translated.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandNo-coding scoreCoding score
ENST00000354179ENST00000393847NSD1chr5176619020+DPEP2chr1668023301-0.0394372270.96056277
ENST00000354179ENST00000412757NSD1chr5176619020+DPEP2chr1668023301-0.037943710.9620562
ENST00000354179ENST00000572888NSD1chr5176619020+DPEP2chr1668023301-0.0347691850.9652308
ENST00000439151ENST00000393847NSD1chr5176619020+DPEP2chr1668023301-0.0013350930.99866486
ENST00000439151ENST00000412757NSD1chr5176619020+DPEP2chr1668023301-0.0013221550.9986778
ENST00000439151ENST00000572888NSD1chr5176619020+DPEP2chr1668023301-0.0014874080.99851257
ENST00000347982ENST00000393847NSD1chr5176619020+DPEP2chr1668023301-0.0373016670.9626984
ENST00000347982ENST00000412757NSD1chr5176619020+DPEP2chr1668023301-0.035577270.96442276
ENST00000347982ENST00000572888NSD1chr5176619020+DPEP2chr1668023301-0.0336390250.96636105

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Fusion Genomic Features for NSD1-DPEP2


check buttonFusionAI prediction of the potential fusion gene breakpoint based on the pre-mature RNA sequence context (+/- 5kb of individual partner genes, total 20kb length sequence). FusionAI is a fusion gene breakpoint classifier based on convolutional neural network by comparing the fusion positive and negative sequence context of ~ 20K fusion gene data. From here, we can have the relative potentency of the 20K genomic sequence how individual sequnce will be likely used as the gene fusion breakpoints.
HgeneHchrHbpHstrandTgeneTchrTbpTstrand1-pp (fusion gene breakpoint)

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions. We integrated a total of 44 different types of human genomic feature loci information across five big categories including virus integration sites, repeats, structural variants, chromatin states, and gene expression regulation. More details are in help page.
genomic feature

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions that are ovelapped with the top 1% feature importance score regions. More details are in help page.

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Fusion Protein Features for NSD1-DPEP2


check button Four levels of functional features of fusion genes
Go to FGviewer search page for the most frequent breakpoint (https://ccsmweb.uth.edu/FGviewer/chr5:176619020/chr16:68023301)
- FGviewer provides the online visualization of the retention search of the protein functional features across DNA, RNA, protein, and pathological levels.
- How to search
1. Put your fusion gene symbol.
2. Press the tab key until there will be shown the breakpoint information filled.
4. Go down and press 'Search' tab twice.
4. Go down to have the hyperlink of the search result.
5. Click the hyperlink.
6. See the FGviewer result for your fusion gene.
FGviewer

check buttonMain function of each fusion partner protein. (from UniProt)
HgeneTgene
..
FUNCTION: Transcriptional activator which is required for calcium-dependent dendritic growth and branching in cortical neurons. Recruits CREB-binding protein (CREBBP) to nuclear bodies. Component of the CREST-BRG1 complex, a multiprotein complex that regulates promoter activation by orchestrating a calcium-dependent release of a repressor complex and a recruitment of an activator complex. In resting neurons, transcription of the c-FOS promoter is inhibited by BRG1-dependent recruitment of a phospho-RB1-HDAC1 repressor complex. Upon calcium influx, RB1 is dephosphorylated by calcineurin, which leads to release of the repressor complex. At the same time, there is increased recruitment of CREBBP to the promoter by a CREST-dependent mechanism, which leads to transcriptional activation. The CREST-BRG1 complex also binds to the NR2B promoter, and activity-dependent induction of NR2B expression involves a release of HDAC1 and recruitment of CREBBP (By similarity). {ECO:0000250}.FUNCTION: Transcriptional activator which is required for calcium-dependent dendritic growth and branching in cortical neurons. Recruits CREB-binding protein (CREBBP) to nuclear bodies. Component of the CREST-BRG1 complex, a multiprotein complex that regulates promoter activation by orchestrating a calcium-dependent release of a repressor complex and a recruitment of an activator complex. In resting neurons, transcription of the c-FOS promoter is inhibited by BRG1-dependent recruitment of a phospho-RB1-HDAC1 repressor complex. Upon calcium influx, RB1 is dephosphorylated by calcineurin, which leads to release of the repressor complex. At the same time, there is increased recruitment of CREBBP to the promoter by a CREST-dependent mechanism, which leads to transcriptional activation. The CREST-BRG1 complex also binds to the NR2B promoter, and activity-dependent induction of NR2B expression involves a release of HDAC1 and recruitment of CREBBP (By similarity). {ECO:0000250}.

check buttonRetention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at

download page


* Minus value of BPloci means that the break pointn is located before the CDS.
- In-frame and retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note

- In-frame and not-retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneNSD1chr5:176619020chr16:68023301ENST00000347982+4242207_2421852428.0Compositional biasNote=Pro-rich
HgeneNSD1chr5:176619020chr16:68023301ENST00000354179+4242207_2421852428.0Compositional biasNote=Pro-rich
HgeneNSD1chr5:176619020chr16:68023301ENST00000361032+1202207_242102594.0Compositional biasNote=Pro-rich
HgeneNSD1chr5:176619020chr16:68023301ENST00000439151+3232207_24213542697.0Compositional biasNote=Pro-rich
HgeneNSD1chr5:176619020chr16:68023301ENST00000347982+4241756_1818852428.0DomainPWWP 2
HgeneNSD1chr5:176619020chr16:68023301ENST00000347982+4241890_1940852428.0DomainAWS
HgeneNSD1chr5:176619020chr16:68023301ENST00000347982+4241942_2059852428.0DomainSET
HgeneNSD1chr5:176619020chr16:68023301ENST00000347982+4242066_2082852428.0DomainPost-SET
HgeneNSD1chr5:176619020chr16:68023301ENST00000347982+424323_388852428.0DomainPWWP 1
HgeneNSD1chr5:176619020chr16:68023301ENST00000354179+4241756_1818852428.0DomainPWWP 2
HgeneNSD1chr5:176619020chr16:68023301ENST00000354179+4241890_1940852428.0DomainAWS
HgeneNSD1chr5:176619020chr16:68023301ENST00000354179+4241942_2059852428.0DomainSET
HgeneNSD1chr5:176619020chr16:68023301ENST00000354179+4242066_2082852428.0DomainPost-SET
HgeneNSD1chr5:176619020chr16:68023301ENST00000354179+424323_388852428.0DomainPWWP 1
HgeneNSD1chr5:176619020chr16:68023301ENST00000361032+1201756_181802594.0DomainPWWP 2
HgeneNSD1chr5:176619020chr16:68023301ENST00000361032+1201890_194002594.0DomainAWS
HgeneNSD1chr5:176619020chr16:68023301ENST00000361032+1201942_205902594.0DomainSET
HgeneNSD1chr5:176619020chr16:68023301ENST00000361032+1202066_208202594.0DomainPost-SET
HgeneNSD1chr5:176619020chr16:68023301ENST00000361032+120323_38802594.0DomainPWWP 1
HgeneNSD1chr5:176619020chr16:68023301ENST00000439151+3231756_18183542697.0DomainPWWP 2
HgeneNSD1chr5:176619020chr16:68023301ENST00000439151+3231890_19403542697.0DomainAWS
HgeneNSD1chr5:176619020chr16:68023301ENST00000439151+3231942_20593542697.0DomainSET
HgeneNSD1chr5:176619020chr16:68023301ENST00000439151+3232066_20823542697.0DomainPost-SET
HgeneNSD1chr5:176619020chr16:68023301ENST00000439151+323323_3883542697.0DomainPWWP 1
HgeneNSD1chr5:176619020chr16:68023301ENST00000347982+4241952_1954852428.0RegionNote=S-adenosyl-L-methionine binding
HgeneNSD1chr5:176619020chr16:68023301ENST00000347982+4241994_1997852428.0RegionNote=S-adenosyl-L-methionine binding
HgeneNSD1chr5:176619020chr16:68023301ENST00000347982+4242020_2021852428.0RegionNote=S-adenosyl-L-methionine binding
HgeneNSD1chr5:176619020chr16:68023301ENST00000347982+4242060_2066852428.0RegionNote=Inhibits enzyme activity in the absence of bound histone
HgeneNSD1chr5:176619020chr16:68023301ENST00000354179+4241952_1954852428.0RegionNote=S-adenosyl-L-methionine binding
HgeneNSD1chr5:176619020chr16:68023301ENST00000354179+4241994_1997852428.0RegionNote=S-adenosyl-L-methionine binding
HgeneNSD1chr5:176619020chr16:68023301ENST00000354179+4242020_2021852428.0RegionNote=S-adenosyl-L-methionine binding
HgeneNSD1chr5:176619020chr16:68023301ENST00000354179+4242060_2066852428.0RegionNote=Inhibits enzyme activity in the absence of bound histone
HgeneNSD1chr5:176619020chr16:68023301ENST00000361032+1201952_195402594.0RegionNote=S-adenosyl-L-methionine binding
HgeneNSD1chr5:176619020chr16:68023301ENST00000361032+1201994_199702594.0RegionNote=S-adenosyl-L-methionine binding
HgeneNSD1chr5:176619020chr16:68023301ENST00000361032+1202020_202102594.0RegionNote=S-adenosyl-L-methionine binding
HgeneNSD1chr5:176619020chr16:68023301ENST00000361032+1202060_206602594.0RegionNote=Inhibits enzyme activity in the absence of bound histone
HgeneNSD1chr5:176619020chr16:68023301ENST00000439151+3231952_19543542697.0RegionNote=S-adenosyl-L-methionine binding
HgeneNSD1chr5:176619020chr16:68023301ENST00000439151+3231994_19973542697.0RegionNote=S-adenosyl-L-methionine binding
HgeneNSD1chr5:176619020chr16:68023301ENST00000439151+3232020_20213542697.0RegionNote=S-adenosyl-L-methionine binding
HgeneNSD1chr5:176619020chr16:68023301ENST00000439151+3232060_20663542697.0RegionNote=Inhibits enzyme activity in the absence of bound histone
HgeneNSD1chr5:176619020chr16:68023301ENST00000347982+4241543_1589852428.0Zinc fingerPHD-type 1
HgeneNSD1chr5:176619020chr16:68023301ENST00000347982+4241590_1646852428.0Zinc fingerPHD-type 2
HgeneNSD1chr5:176619020chr16:68023301ENST00000347982+4241707_1751852428.0Zinc fingerPHD-type 3
HgeneNSD1chr5:176619020chr16:68023301ENST00000347982+4242118_2165852428.0Zinc fingerPHD-type 4%3B atypical
HgeneNSD1chr5:176619020chr16:68023301ENST00000354179+4241543_1589852428.0Zinc fingerPHD-type 1
HgeneNSD1chr5:176619020chr16:68023301ENST00000354179+4241590_1646852428.0Zinc fingerPHD-type 2
HgeneNSD1chr5:176619020chr16:68023301ENST00000354179+4241707_1751852428.0Zinc fingerPHD-type 3
HgeneNSD1chr5:176619020chr16:68023301ENST00000354179+4242118_2165852428.0Zinc fingerPHD-type 4%3B atypical
HgeneNSD1chr5:176619020chr16:68023301ENST00000361032+1201543_158902594.0Zinc fingerPHD-type 1
HgeneNSD1chr5:176619020chr16:68023301ENST00000361032+1201590_164602594.0Zinc fingerPHD-type 2
HgeneNSD1chr5:176619020chr16:68023301ENST00000361032+1201707_175102594.0Zinc fingerPHD-type 3
HgeneNSD1chr5:176619020chr16:68023301ENST00000361032+1202118_216502594.0Zinc fingerPHD-type 4%3B atypical
HgeneNSD1chr5:176619020chr16:68023301ENST00000439151+3231543_15893542697.0Zinc fingerPHD-type 1
HgeneNSD1chr5:176619020chr16:68023301ENST00000439151+3231590_16463542697.0Zinc fingerPHD-type 2
HgeneNSD1chr5:176619020chr16:68023301ENST00000439151+3231707_17513542697.0Zinc fingerPHD-type 3
HgeneNSD1chr5:176619020chr16:68023301ENST00000439151+3232118_21653542697.0Zinc fingerPHD-type 4%3B atypical


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Fusion Gene Sequence for NSD1-DPEP2


check button For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. To have fusion amino acid sequence, we ran ORFfinder and chose the longest ORF among the all predicted ones.
>60416_60416_1_NSD1-DPEP2_NSD1_chr5_176619020_ENST00000347982_DPEP2_chr16_68023301_ENST00000393847_length(transcript)=936nt_BP=357nt
CCTCCGCCTCCCCTCAGGTTGATGCCGGCCCAGGATGGATCAGACCTGTGAACTACCCAGAAGAAATTGTCTGCTGCCCTTTTCCAATCC
AGTGAATTTAGATGCCCCTGAAGACAAGGACAGCCCTTTCGGATGATCCAGATTCCAGTACCAGTACATTAGGAAACATGCTAGAATTAC
CTGGAACTTCATCATCATCTACTTCACAGGAATTGCCATTTTGTCAACCTAAGAAAAAGTCTACGCCACTGAAGTATGAAGTTGGAGATC
TCATCTGGGCAAAATTCAAGAGACGCCCATGGTGGCCCTGCAGGATTTGTTCTGATCCGTTGATTAACACACATTCAAAAATGAAAGATC
ACTTCGACCACATCAAGGCTGTCATTGGATCCAAGTTCATCGGGATTGGTGGAGATTATGATGGGGCCGGCAAATTCCCTCAGGGGCTGG
AAGACGTGTCCACATACCCGGTCCTGATAGAGGAGTTGCTGAGTCGTGGCTGGAGTGAGGAAGAGCTTCAGGGTGTCCTTCGTGGAAACC
TGCTGCGGGTCTTCAGACAAGTGGAAAAGGTACAGGAAGAAAACAAATGGCAAAGCCCCTTGGAGGACAAGTTCCCGGATGAGCAGCTGA
GCAGTTCCTGCCACTCCGACCTCTCACGTCTGCGTCAGAGACAGAGTCTGACTTCAGGCCAGGAACTCACTGAGATTCCCATACACTGGA
CAGCCAAGTTACCAGCCAAGTGGTCAGTCTCAGAGTCCTCCCCCCACATGGCCCCAGTCCTTGCAGTTGTGGCCACCTTCCCAGTCCTTA
TTCTGTGGCTCTGATGACCCAGTTAGTCCTGCCAGATGTCACTGTAGCAAGCCACAGACACCCCACAAAGTTCCCCTGTTGTGCAGGCAC

>60416_60416_1_NSD1-DPEP2_NSD1_chr5_176619020_ENST00000347982_DPEP2_chr16_68023301_ENST00000393847_length(amino acids)=240AA_BP=85
MPLKTRTALSDDPDSSTSTLGNMLELPGTSSSSTSQELPFCQPKKKSTPLKYEVGDLIWAKFKRRPWWPCRICSDPLINTHSKMKDHFDH
IKAVIGSKFIGIGGDYDGAGKFPQGLEDVSTYPVLIEELLSRGWSEEELQGVLRGNLLRVFRQVEKVQEENKWQSPLEDKFPDEQLSSSC

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>60416_60416_2_NSD1-DPEP2_NSD1_chr5_176619020_ENST00000347982_DPEP2_chr16_68023301_ENST00000412757_length(transcript)=933nt_BP=357nt
CCTCCGCCTCCCCTCAGGTTGATGCCGGCCCAGGATGGATCAGACCTGTGAACTACCCAGAAGAAATTGTCTGCTGCCCTTTTCCAATCC
AGTGAATTTAGATGCCCCTGAAGACAAGGACAGCCCTTTCGGATGATCCAGATTCCAGTACCAGTACATTAGGAAACATGCTAGAATTAC
CTGGAACTTCATCATCATCTACTTCACAGGAATTGCCATTTTGTCAACCTAAGAAAAAGTCTACGCCACTGAAGTATGAAGTTGGAGATC
TCATCTGGGCAAAATTCAAGAGACGCCCATGGTGGCCCTGCAGGATTTGTTCTGATCCGTTGATTAACACACATTCAAAAATGAAAGATC
ACTTCGACCACATCAAGGCTGTCATTGGATCCAAGTTCATCGGGATTGGTGGAGATTATGATGGGGCCGGCAAATTCCCTCAGGGGCTGG
AAGACGTGTCCACATACCCGGTCCTGATAGAGGAGTTGCTGAGTCGTGGCTGGAGTGAGGAAGAGCTTCAGGGTGTCCTTCGTGGAAACC
TGCTGCGGGTCTTCAGACAAGTGGAAAAGGTACAGGAAGAAAACAAATGGCAAAGCCCCTTGGAGGACAAGTTCCCGGATGAGCAGCTGA
GCAGTTCCTGCCACTCCGACCTCTCACGTCTGCGTCAGAGACAGAGTCTGACTTCAGGCCAGGAACTCACTGAGATTCCCATACACTGGA
CAGCCAAGTTACCAGCCAAGTGGTCAGTCTCAGAGTCCTCCCCCCACATGGCCCCAGTCCTTGCAGTTGTGGCCACCTTCCCAGTCCTTA
TTCTGTGGCTCTGATGACCCAGTTAGTCCTGCCAGATGTCACTGTAGCAAGCCACAGACACCCCACAAAGTTCCCCTGTTGTGCAGGCAC

>60416_60416_2_NSD1-DPEP2_NSD1_chr5_176619020_ENST00000347982_DPEP2_chr16_68023301_ENST00000412757_length(amino acids)=240AA_BP=85
MPLKTRTALSDDPDSSTSTLGNMLELPGTSSSSTSQELPFCQPKKKSTPLKYEVGDLIWAKFKRRPWWPCRICSDPLINTHSKMKDHFDH
IKAVIGSKFIGIGGDYDGAGKFPQGLEDVSTYPVLIEELLSRGWSEEELQGVLRGNLLRVFRQVEKVQEENKWQSPLEDKFPDEQLSSSC

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>60416_60416_3_NSD1-DPEP2_NSD1_chr5_176619020_ENST00000347982_DPEP2_chr16_68023301_ENST00000572888_length(transcript)=824nt_BP=357nt
CCTCCGCCTCCCCTCAGGTTGATGCCGGCCCAGGATGGATCAGACCTGTGAACTACCCAGAAGAAATTGTCTGCTGCCCTTTTCCAATCC
AGTGAATTTAGATGCCCCTGAAGACAAGGACAGCCCTTTCGGATGATCCAGATTCCAGTACCAGTACATTAGGAAACATGCTAGAATTAC
CTGGAACTTCATCATCATCTACTTCACAGGAATTGCCATTTTGTCAACCTAAGAAAAAGTCTACGCCACTGAAGTATGAAGTTGGAGATC
TCATCTGGGCAAAATTCAAGAGACGCCCATGGTGGCCCTGCAGGATTTGTTCTGATCCGTTGATTAACACACATTCAAAAATGAAAGATC
ACTTCGACCACATCAAGGCTGTCATTGGATCCAAGTTCATCGGGATTGGTGGAGATTATGATGGGGCCGGCAAATTCCCTCAGGGGCTGG
AAGACGTGTCCACATACCCGGTCCTGATAGAGGAGTTGCTGAGTCGTGGCTGGAGTGAGGAAGAGCTTCAGGGTGTCCTTCGTGGAAACC
TGCTGCGGGTCTTCAGACAAGTGGAAAAGGTACAGGAAGAAAACAAATGGCAAAGCCCCTTGGAGGACAAGTTCCCGGATGAGCAGCTGA
GCAGTTCCTGCCACTCCGACCTCTCACGTCTGCGTCAGAGACAGAGTCTGACTTCAGGCCAGGAACTCACTGAGATTCCCATACACTGGA
CAGCCAAGTTACCAGCCAAGTGGTCAGTCTCAGAGTCCTCCCCCCACATGGCCCCAGTCCTTGCAGTTGTGGCCACCTTCCCAGTCCTTA

>60416_60416_3_NSD1-DPEP2_NSD1_chr5_176619020_ENST00000347982_DPEP2_chr16_68023301_ENST00000572888_length(amino acids)=241AA_BP=85
MPLKTRTALSDDPDSSTSTLGNMLELPGTSSSSTSQELPFCQPKKKSTPLKYEVGDLIWAKFKRRPWWPCRICSDPLINTHSKMKDHFDH
IKAVIGSKFIGIGGDYDGAGKFPQGLEDVSTYPVLIEELLSRGWSEEELQGVLRGNLLRVFRQVEKVQEENKWQSPLEDKFPDEQLSSSC

--------------------------------------------------------------
>60416_60416_4_NSD1-DPEP2_NSD1_chr5_176619020_ENST00000354179_DPEP2_chr16_68023301_ENST00000393847_length(transcript)=995nt_BP=416nt
GGCCGGGTAGGGGGTTCGCCTGCGGCCGCGTCTGCTCGGGGCCTGAGGCCTCGAAGACCCCAGCCCAAGCCCCCAGGTTGATGCCGGCCC
AGGATGGATCAGACCTGTGAACTACCCAGAAGAAATTGTCTGCTGCCCTTTTCCAATCCAGTGAATTTAGATGCCCCTGAAGACAAGGAC
AGCCCTTTCGGATGATCCAGATTCCAGTACCAGTACATTAGGAAACATGCTAGAATTACCTGGAACTTCATCATCATCTACTTCACAGGA
ATTGCCATTTTGTCAACCTAAGAAAAAGTCTACGCCACTGAAGTATGAAGTTGGAGATCTCATCTGGGCAAAATTCAAGAGACGCCCATG
GTGGCCCTGCAGGATTTGTTCTGATCCGTTGATTAACACACATTCAAAAATGAAAGATCACTTCGACCACATCAAGGCTGTCATTGGATC
CAAGTTCATCGGGATTGGTGGAGATTATGATGGGGCCGGCAAATTCCCTCAGGGGCTGGAAGACGTGTCCACATACCCGGTCCTGATAGA
GGAGTTGCTGAGTCGTGGCTGGAGTGAGGAAGAGCTTCAGGGTGTCCTTCGTGGAAACCTGCTGCGGGTCTTCAGACAAGTGGAAAAGGT
ACAGGAAGAAAACAAATGGCAAAGCCCCTTGGAGGACAAGTTCCCGGATGAGCAGCTGAGCAGTTCCTGCCACTCCGACCTCTCACGTCT
GCGTCAGAGACAGAGTCTGACTTCAGGCCAGGAACTCACTGAGATTCCCATACACTGGACAGCCAAGTTACCAGCCAAGTGGTCAGTCTC
AGAGTCCTCCCCCCACATGGCCCCAGTCCTTGCAGTTGTGGCCACCTTCCCAGTCCTTATTCTGTGGCTCTGATGACCCAGTTAGTCCTG
CCAGATGTCACTGTAGCAAGCCACAGACACCCCACAAAGTTCCCCTGTTGTGCAGGCACAAATATTTCCTGAAATAAATGTTTTGGACAT

>60416_60416_4_NSD1-DPEP2_NSD1_chr5_176619020_ENST00000354179_DPEP2_chr16_68023301_ENST00000393847_length(amino acids)=240AA_BP=85
MPLKTRTALSDDPDSSTSTLGNMLELPGTSSSSTSQELPFCQPKKKSTPLKYEVGDLIWAKFKRRPWWPCRICSDPLINTHSKMKDHFDH
IKAVIGSKFIGIGGDYDGAGKFPQGLEDVSTYPVLIEELLSRGWSEEELQGVLRGNLLRVFRQVEKVQEENKWQSPLEDKFPDEQLSSSC

--------------------------------------------------------------
>60416_60416_5_NSD1-DPEP2_NSD1_chr5_176619020_ENST00000354179_DPEP2_chr16_68023301_ENST00000412757_length(transcript)=992nt_BP=416nt
GGCCGGGTAGGGGGTTCGCCTGCGGCCGCGTCTGCTCGGGGCCTGAGGCCTCGAAGACCCCAGCCCAAGCCCCCAGGTTGATGCCGGCCC
AGGATGGATCAGACCTGTGAACTACCCAGAAGAAATTGTCTGCTGCCCTTTTCCAATCCAGTGAATTTAGATGCCCCTGAAGACAAGGAC
AGCCCTTTCGGATGATCCAGATTCCAGTACCAGTACATTAGGAAACATGCTAGAATTACCTGGAACTTCATCATCATCTACTTCACAGGA
ATTGCCATTTTGTCAACCTAAGAAAAAGTCTACGCCACTGAAGTATGAAGTTGGAGATCTCATCTGGGCAAAATTCAAGAGACGCCCATG
GTGGCCCTGCAGGATTTGTTCTGATCCGTTGATTAACACACATTCAAAAATGAAAGATCACTTCGACCACATCAAGGCTGTCATTGGATC
CAAGTTCATCGGGATTGGTGGAGATTATGATGGGGCCGGCAAATTCCCTCAGGGGCTGGAAGACGTGTCCACATACCCGGTCCTGATAGA
GGAGTTGCTGAGTCGTGGCTGGAGTGAGGAAGAGCTTCAGGGTGTCCTTCGTGGAAACCTGCTGCGGGTCTTCAGACAAGTGGAAAAGGT
ACAGGAAGAAAACAAATGGCAAAGCCCCTTGGAGGACAAGTTCCCGGATGAGCAGCTGAGCAGTTCCTGCCACTCCGACCTCTCACGTCT
GCGTCAGAGACAGAGTCTGACTTCAGGCCAGGAACTCACTGAGATTCCCATACACTGGACAGCCAAGTTACCAGCCAAGTGGTCAGTCTC
AGAGTCCTCCCCCCACATGGCCCCAGTCCTTGCAGTTGTGGCCACCTTCCCAGTCCTTATTCTGTGGCTCTGATGACCCAGTTAGTCCTG
CCAGATGTCACTGTAGCAAGCCACAGACACCCCACAAAGTTCCCCTGTTGTGCAGGCACAAATATTTCCTGAAATAAATGTTTTGGACAT

>60416_60416_5_NSD1-DPEP2_NSD1_chr5_176619020_ENST00000354179_DPEP2_chr16_68023301_ENST00000412757_length(amino acids)=240AA_BP=85
MPLKTRTALSDDPDSSTSTLGNMLELPGTSSSSTSQELPFCQPKKKSTPLKYEVGDLIWAKFKRRPWWPCRICSDPLINTHSKMKDHFDH
IKAVIGSKFIGIGGDYDGAGKFPQGLEDVSTYPVLIEELLSRGWSEEELQGVLRGNLLRVFRQVEKVQEENKWQSPLEDKFPDEQLSSSC

--------------------------------------------------------------
>60416_60416_6_NSD1-DPEP2_NSD1_chr5_176619020_ENST00000354179_DPEP2_chr16_68023301_ENST00000572888_length(transcript)=883nt_BP=416nt
GGCCGGGTAGGGGGTTCGCCTGCGGCCGCGTCTGCTCGGGGCCTGAGGCCTCGAAGACCCCAGCCCAAGCCCCCAGGTTGATGCCGGCCC
AGGATGGATCAGACCTGTGAACTACCCAGAAGAAATTGTCTGCTGCCCTTTTCCAATCCAGTGAATTTAGATGCCCCTGAAGACAAGGAC
AGCCCTTTCGGATGATCCAGATTCCAGTACCAGTACATTAGGAAACATGCTAGAATTACCTGGAACTTCATCATCATCTACTTCACAGGA
ATTGCCATTTTGTCAACCTAAGAAAAAGTCTACGCCACTGAAGTATGAAGTTGGAGATCTCATCTGGGCAAAATTCAAGAGACGCCCATG
GTGGCCCTGCAGGATTTGTTCTGATCCGTTGATTAACACACATTCAAAAATGAAAGATCACTTCGACCACATCAAGGCTGTCATTGGATC
CAAGTTCATCGGGATTGGTGGAGATTATGATGGGGCCGGCAAATTCCCTCAGGGGCTGGAAGACGTGTCCACATACCCGGTCCTGATAGA
GGAGTTGCTGAGTCGTGGCTGGAGTGAGGAAGAGCTTCAGGGTGTCCTTCGTGGAAACCTGCTGCGGGTCTTCAGACAAGTGGAAAAGGT
ACAGGAAGAAAACAAATGGCAAAGCCCCTTGGAGGACAAGTTCCCGGATGAGCAGCTGAGCAGTTCCTGCCACTCCGACCTCTCACGTCT
GCGTCAGAGACAGAGTCTGACTTCAGGCCAGGAACTCACTGAGATTCCCATACACTGGACAGCCAAGTTACCAGCCAAGTGGTCAGTCTC

>60416_60416_6_NSD1-DPEP2_NSD1_chr5_176619020_ENST00000354179_DPEP2_chr16_68023301_ENST00000572888_length(amino acids)=241AA_BP=85
MPLKTRTALSDDPDSSTSTLGNMLELPGTSSSSTSQELPFCQPKKKSTPLKYEVGDLIWAKFKRRPWWPCRICSDPLINTHSKMKDHFDH
IKAVIGSKFIGIGGDYDGAGKFPQGLEDVSTYPVLIEELLSRGWSEEELQGVLRGNLLRVFRQVEKVQEENKWQSPLEDKFPDEQLSSSC

--------------------------------------------------------------
>60416_60416_7_NSD1-DPEP2_NSD1_chr5_176619020_ENST00000439151_DPEP2_chr16_68023301_ENST00000393847_length(transcript)=1687nt_BP=1108nt
GCTGGCCCGGGAGGGGGCGCGGGGCACGGTTGATGCCGGCCCAGGATGGATCAGACCTGTGAACTACCCAGAAGAAATTGTCTGCTGCCC
TTTTCCAATCCAGTGAATTTAGATGCCCCTGAAGACAAGGACAGCCCTTTCGGTAATGGTCAATCCAATTTTTCTGAGCCACTTAATGGG
TGTACTATGCAGTTATCGACTGTCAGTGGAACATCCCAAAATGCTTATGGACAAGATTCTCCATCTTGTTACATTCCACTGCGGAGACTA
CAGGATTTGGCCTCCATGATCAATGTAGAGTATTTAAATGGGTCTGCTGATGGATCAGAATCCTTTCAAGACCCTGAAAAAAGTGATTCA
AGAGCTCAGACGCCAATTGTTTGCACTTCCTTGAGTCCTGGTGGTCCTACAGCACTTGCTATGAAACAGGAACCCTCTTGTAATAACTCC
CCTGAACTCCAGGTAAAAGTAACAAAGACTATCAAGAATGGCTTTCTGCACTTTGAGAATTTTACTTGTGTGGACGATGCAGATGTAGAT
TCTGAAATGGACCCAGAACAGCCAGTCACAGAGGATGAGAGTATAGAGGAGATCTTTGAGGAAACTCAGACCAATGCCACCTGCAATTAT
GAGACTAAATCAGAGAATGGTGTAAAAGTGGCCATGGGAAGTGAACAAGACAGCACACCAGAGAGTAGACACGGTGCAGTCAAATCGCCA
TTCTTGCCATTAGCTCCTCAGACTGAAACACAGAAAAATAAGCAAAGAAATGAAGTGGACGGCAGCAATGAAAAAGCAGCCCTTCTCCCA
GCCCCCTTTTCACTAGGAGACACAAACATTACAATAGAAGAGCAATTAAACTCAATAAATTTATCTTTTCAGGATGATCCAGATTCCAGT
ACCAGTACATTAGGAAACATGCTAGAATTACCTGGAACTTCATCATCATCTACTTCACAGGAATTGCCATTTTGTCAACCTAAGAAAAAG
TCTACGCCACTGAAGTATGAAGTTGGAGATCTCATCTGGGCAAAATTCAAGAGACGCCCATGGTGGCCCTGCAGGATTTGTTCTGATCCG
TTGATTAACACACATTCAAAAATGAAAGATCACTTCGACCACATCAAGGCTGTCATTGGATCCAAGTTCATCGGGATTGGTGGAGATTAT
GATGGGGCCGGCAAATTCCCTCAGGGGCTGGAAGACGTGTCCACATACCCGGTCCTGATAGAGGAGTTGCTGAGTCGTGGCTGGAGTGAG
GAAGAGCTTCAGGGTGTCCTTCGTGGAAACCTGCTGCGGGTCTTCAGACAAGTGGAAAAGGTACAGGAAGAAAACAAATGGCAAAGCCCC
TTGGAGGACAAGTTCCCGGATGAGCAGCTGAGCAGTTCCTGCCACTCCGACCTCTCACGTCTGCGTCAGAGACAGAGTCTGACTTCAGGC
CAGGAACTCACTGAGATTCCCATACACTGGACAGCCAAGTTACCAGCCAAGTGGTCAGTCTCAGAGTCCTCCCCCCACATGGCCCCAGTC
CTTGCAGTTGTGGCCACCTTCCCAGTCCTTATTCTGTGGCTCTGATGACCCAGTTAGTCCTGCCAGATGTCACTGTAGCAAGCCACAGAC

>60416_60416_7_NSD1-DPEP2_NSD1_chr5_176619020_ENST00000439151_DPEP2_chr16_68023301_ENST00000393847_length(amino acids)=509AA_BP=354
MDQTCELPRRNCLLPFSNPVNLDAPEDKDSPFGNGQSNFSEPLNGCTMQLSTVSGTSQNAYGQDSPSCYIPLRRLQDLASMINVEYLNGS
ADGSESFQDPEKSDSRAQTPIVCTSLSPGGPTALAMKQEPSCNNSPELQVKVTKTIKNGFLHFENFTCVDDADVDSEMDPEQPVTEDESI
EEIFEETQTNATCNYETKSENGVKVAMGSEQDSTPESRHGAVKSPFLPLAPQTETQKNKQRNEVDGSNEKAALLPAPFSLGDTNITIEEQ
LNSINLSFQDDPDSSTSTLGNMLELPGTSSSSTSQELPFCQPKKKSTPLKYEVGDLIWAKFKRRPWWPCRICSDPLINTHSKMKDHFDHI
KAVIGSKFIGIGGDYDGAGKFPQGLEDVSTYPVLIEELLSRGWSEEELQGVLRGNLLRVFRQVEKVQEENKWQSPLEDKFPDEQLSSSCH

--------------------------------------------------------------
>60416_60416_8_NSD1-DPEP2_NSD1_chr5_176619020_ENST00000439151_DPEP2_chr16_68023301_ENST00000412757_length(transcript)=1684nt_BP=1108nt
GCTGGCCCGGGAGGGGGCGCGGGGCACGGTTGATGCCGGCCCAGGATGGATCAGACCTGTGAACTACCCAGAAGAAATTGTCTGCTGCCC
TTTTCCAATCCAGTGAATTTAGATGCCCCTGAAGACAAGGACAGCCCTTTCGGTAATGGTCAATCCAATTTTTCTGAGCCACTTAATGGG
TGTACTATGCAGTTATCGACTGTCAGTGGAACATCCCAAAATGCTTATGGACAAGATTCTCCATCTTGTTACATTCCACTGCGGAGACTA
CAGGATTTGGCCTCCATGATCAATGTAGAGTATTTAAATGGGTCTGCTGATGGATCAGAATCCTTTCAAGACCCTGAAAAAAGTGATTCA
AGAGCTCAGACGCCAATTGTTTGCACTTCCTTGAGTCCTGGTGGTCCTACAGCACTTGCTATGAAACAGGAACCCTCTTGTAATAACTCC
CCTGAACTCCAGGTAAAAGTAACAAAGACTATCAAGAATGGCTTTCTGCACTTTGAGAATTTTACTTGTGTGGACGATGCAGATGTAGAT
TCTGAAATGGACCCAGAACAGCCAGTCACAGAGGATGAGAGTATAGAGGAGATCTTTGAGGAAACTCAGACCAATGCCACCTGCAATTAT
GAGACTAAATCAGAGAATGGTGTAAAAGTGGCCATGGGAAGTGAACAAGACAGCACACCAGAGAGTAGACACGGTGCAGTCAAATCGCCA
TTCTTGCCATTAGCTCCTCAGACTGAAACACAGAAAAATAAGCAAAGAAATGAAGTGGACGGCAGCAATGAAAAAGCAGCCCTTCTCCCA
GCCCCCTTTTCACTAGGAGACACAAACATTACAATAGAAGAGCAATTAAACTCAATAAATTTATCTTTTCAGGATGATCCAGATTCCAGT
ACCAGTACATTAGGAAACATGCTAGAATTACCTGGAACTTCATCATCATCTACTTCACAGGAATTGCCATTTTGTCAACCTAAGAAAAAG
TCTACGCCACTGAAGTATGAAGTTGGAGATCTCATCTGGGCAAAATTCAAGAGACGCCCATGGTGGCCCTGCAGGATTTGTTCTGATCCG
TTGATTAACACACATTCAAAAATGAAAGATCACTTCGACCACATCAAGGCTGTCATTGGATCCAAGTTCATCGGGATTGGTGGAGATTAT
GATGGGGCCGGCAAATTCCCTCAGGGGCTGGAAGACGTGTCCACATACCCGGTCCTGATAGAGGAGTTGCTGAGTCGTGGCTGGAGTGAG
GAAGAGCTTCAGGGTGTCCTTCGTGGAAACCTGCTGCGGGTCTTCAGACAAGTGGAAAAGGTACAGGAAGAAAACAAATGGCAAAGCCCC
TTGGAGGACAAGTTCCCGGATGAGCAGCTGAGCAGTTCCTGCCACTCCGACCTCTCACGTCTGCGTCAGAGACAGAGTCTGACTTCAGGC
CAGGAACTCACTGAGATTCCCATACACTGGACAGCCAAGTTACCAGCCAAGTGGTCAGTCTCAGAGTCCTCCCCCCACATGGCCCCAGTC
CTTGCAGTTGTGGCCACCTTCCCAGTCCTTATTCTGTGGCTCTGATGACCCAGTTAGTCCTGCCAGATGTCACTGTAGCAAGCCACAGAC

>60416_60416_8_NSD1-DPEP2_NSD1_chr5_176619020_ENST00000439151_DPEP2_chr16_68023301_ENST00000412757_length(amino acids)=509AA_BP=354
MDQTCELPRRNCLLPFSNPVNLDAPEDKDSPFGNGQSNFSEPLNGCTMQLSTVSGTSQNAYGQDSPSCYIPLRRLQDLASMINVEYLNGS
ADGSESFQDPEKSDSRAQTPIVCTSLSPGGPTALAMKQEPSCNNSPELQVKVTKTIKNGFLHFENFTCVDDADVDSEMDPEQPVTEDESI
EEIFEETQTNATCNYETKSENGVKVAMGSEQDSTPESRHGAVKSPFLPLAPQTETQKNKQRNEVDGSNEKAALLPAPFSLGDTNITIEEQ
LNSINLSFQDDPDSSTSTLGNMLELPGTSSSSTSQELPFCQPKKKSTPLKYEVGDLIWAKFKRRPWWPCRICSDPLINTHSKMKDHFDHI
KAVIGSKFIGIGGDYDGAGKFPQGLEDVSTYPVLIEELLSRGWSEEELQGVLRGNLLRVFRQVEKVQEENKWQSPLEDKFPDEQLSSSCH

--------------------------------------------------------------
>60416_60416_9_NSD1-DPEP2_NSD1_chr5_176619020_ENST00000439151_DPEP2_chr16_68023301_ENST00000572888_length(transcript)=1575nt_BP=1108nt
GCTGGCCCGGGAGGGGGCGCGGGGCACGGTTGATGCCGGCCCAGGATGGATCAGACCTGTGAACTACCCAGAAGAAATTGTCTGCTGCCC
TTTTCCAATCCAGTGAATTTAGATGCCCCTGAAGACAAGGACAGCCCTTTCGGTAATGGTCAATCCAATTTTTCTGAGCCACTTAATGGG
TGTACTATGCAGTTATCGACTGTCAGTGGAACATCCCAAAATGCTTATGGACAAGATTCTCCATCTTGTTACATTCCACTGCGGAGACTA
CAGGATTTGGCCTCCATGATCAATGTAGAGTATTTAAATGGGTCTGCTGATGGATCAGAATCCTTTCAAGACCCTGAAAAAAGTGATTCA
AGAGCTCAGACGCCAATTGTTTGCACTTCCTTGAGTCCTGGTGGTCCTACAGCACTTGCTATGAAACAGGAACCCTCTTGTAATAACTCC
CCTGAACTCCAGGTAAAAGTAACAAAGACTATCAAGAATGGCTTTCTGCACTTTGAGAATTTTACTTGTGTGGACGATGCAGATGTAGAT
TCTGAAATGGACCCAGAACAGCCAGTCACAGAGGATGAGAGTATAGAGGAGATCTTTGAGGAAACTCAGACCAATGCCACCTGCAATTAT
GAGACTAAATCAGAGAATGGTGTAAAAGTGGCCATGGGAAGTGAACAAGACAGCACACCAGAGAGTAGACACGGTGCAGTCAAATCGCCA
TTCTTGCCATTAGCTCCTCAGACTGAAACACAGAAAAATAAGCAAAGAAATGAAGTGGACGGCAGCAATGAAAAAGCAGCCCTTCTCCCA
GCCCCCTTTTCACTAGGAGACACAAACATTACAATAGAAGAGCAATTAAACTCAATAAATTTATCTTTTCAGGATGATCCAGATTCCAGT
ACCAGTACATTAGGAAACATGCTAGAATTACCTGGAACTTCATCATCATCTACTTCACAGGAATTGCCATTTTGTCAACCTAAGAAAAAG
TCTACGCCACTGAAGTATGAAGTTGGAGATCTCATCTGGGCAAAATTCAAGAGACGCCCATGGTGGCCCTGCAGGATTTGTTCTGATCCG
TTGATTAACACACATTCAAAAATGAAAGATCACTTCGACCACATCAAGGCTGTCATTGGATCCAAGTTCATCGGGATTGGTGGAGATTAT
GATGGGGCCGGCAAATTCCCTCAGGGGCTGGAAGACGTGTCCACATACCCGGTCCTGATAGAGGAGTTGCTGAGTCGTGGCTGGAGTGAG
GAAGAGCTTCAGGGTGTCCTTCGTGGAAACCTGCTGCGGGTCTTCAGACAAGTGGAAAAGGTACAGGAAGAAAACAAATGGCAAAGCCCC
TTGGAGGACAAGTTCCCGGATGAGCAGCTGAGCAGTTCCTGCCACTCCGACCTCTCACGTCTGCGTCAGAGACAGAGTCTGACTTCAGGC
CAGGAACTCACTGAGATTCCCATACACTGGACAGCCAAGTTACCAGCCAAGTGGTCAGTCTCAGAGTCCTCCCCCCACATGGCCCCAGTC

>60416_60416_9_NSD1-DPEP2_NSD1_chr5_176619020_ENST00000439151_DPEP2_chr16_68023301_ENST00000572888_length(amino acids)=509AA_BP=354
MDQTCELPRRNCLLPFSNPVNLDAPEDKDSPFGNGQSNFSEPLNGCTMQLSTVSGTSQNAYGQDSPSCYIPLRRLQDLASMINVEYLNGS
ADGSESFQDPEKSDSRAQTPIVCTSLSPGGPTALAMKQEPSCNNSPELQVKVTKTIKNGFLHFENFTCVDDADVDSEMDPEQPVTEDESI
EEIFEETQTNATCNYETKSENGVKVAMGSEQDSTPESRHGAVKSPFLPLAPQTETQKNKQRNEVDGSNEKAALLPAPFSLGDTNITIEEQ
LNSINLSFQDDPDSSTSTLGNMLELPGTSSSSTSQELPFCQPKKKSTPLKYEVGDLIWAKFKRRPWWPCRICSDPLINTHSKMKDHFDHI
KAVIGSKFIGIGGDYDGAGKFPQGLEDVSTYPVLIEELLSRGWSEEELQGVLRGNLLRVFRQVEKVQEENKWQSPLEDKFPDEQLSSSCH

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Fusion Gene PPI Analysis for NSD1-DPEP2


check button Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in

ChiPPI page.


check button Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160)
HgeneHgene's interactorsTgeneTgene's interactors


check button - Retained PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenStill interaction with


check button - Lost PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


check button - Retained PPIs, but lost function due to frame-shift fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


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Related Drugs for NSD1-DPEP2


check button Drugs targeting genes involved in this fusion gene.
(DrugBank Version 5.1.8 2021-05-08)
PartnerGeneUniProtAccDrugBank IDDrug nameDrug activityDrug typeDrug status

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Related Diseases for NSD1-DPEP2


check button Diseases associated with fusion partners.
(DisGeNet 4.0)
PartnerGeneDisease IDDisease name# pubmedsSource