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 | Fusion Gene Summary |
| Fusion Gene ORF analysis |
| Fusion Genomic Features |
| Fusion Protein Features |
| Fusion Gene Sequence |
| Fusion Gene PPI analysis |
| Related Drugs |
| Related Diseases |
Fusion gene:NSD1-FAT2 (FusionGDB2 ID:60418) |
Fusion Gene Summary for NSD1-FAT2 |
 Fusion gene summary |
| Fusion gene information | Fusion gene name: NSD1-FAT2 | Fusion gene ID: 60418 | Hgene | Tgene | Gene symbol | NSD1 | FAT2 | Gene ID | 64324 | 2196 |
| Gene name | nuclear receptor binding SET domain protein 1 | FAT atypical cadherin 2 | |
| Synonyms | ARA267|KMT3B|SOTOS|SOTOS1|STO | CDHF8|CDHR9|HFAT2|MEGF1|SCA45 | |
| Cytomap | 5q35.3 | 5q33.1 | |
| Type of gene | protein-coding | protein-coding | |
| Description | histone-lysine N-methyltransferase, H3 lysine-36 and H4 lysine-20 specificH3-K36-HMTaseH4-K20-HMTaseNR-binding SET domain-containing proteinandrogen receptor coactivator 267 kDa proteinandrogen receptor-associated coregulator 267androgen receptor-as | protocadherin Fat 2FAT tumor suppressor homolog 2cadherin family member 8cadherin-related family member 9multiple EGF-like domains protein 1multiple epidermal growth factor-like domains 1multiple epidermal growth factor-like domains protein 1protoc | |
| Modification date | 20200321 | 20200313 | |
| UniProtAcc | . | Q9NYQ8 | |
| Ensembl transtripts involved in fusion gene | ENST00000347982, ENST00000354179, ENST00000361032, ENST00000439151, ENST00000511258, | ENST00000261800, | |
| Fusion gene scores | * DoF score | 23 X 14 X 17=5474 | 2 X 2 X 2=8 |
| # samples | 37 | 2 | |
| ** MAII score | log2(37/5474*10)=-3.88699825884864 possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs). DoF>8 and MAII<0 | log2(2/8*10)=1.32192809488736 | |
| Context | PubMed: NSD1 [Title/Abstract] AND FAT2 [Title/Abstract] AND fusion [Title/Abstract] | ||
| Most frequent breakpoint | NSD1(176675325)-FAT2(150892167), # samples:2 | ||
| Anticipated loss of major functional domain due to fusion event. | |||
| * DoF score (Degree of Frequency) = # partners X # break points X # cancer types ** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10) |
| Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez |
| Partner | Gene | GO ID | GO term | PubMed ID |
| Hgene | NSD1 | GO:0045893 | positive regulation of transcription, DNA-templated | 11509567 |
| Tgene | FAT2 | GO:0010631 | epithelial cell migration | 29053796 |
| Tgene | FAT2 | GO:0031589 | cell-substrate adhesion | 29053796 |
| Fusion gene breakpoints across NSD1 (5'-gene) * Click on the image to open the UCSC genome browser with custom track showing this image in a new window. |
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| Fusion gene breakpoints across FAT2 (3'-gene) * Click on the image to open the UCSC genome browser with custom track showing this image in a new window. |
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| Fusion gene information from two resources (ChiTars 5.0 and ChimerDB 4.0) * All genome coordinats were lifted-over on hg19. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| Source | Disease | Sample | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| ChimerDB4 | BLCA | TCGA-BT-A20T-01A | NSD1 | chr5 | 176675325 | - | FAT2 | chr5 | 150892167 | - |
| ChimerDB4 | BLCA | TCGA-BT-A20T-01A | NSD1 | chr5 | 176675325 | + | FAT2 | chr5 | 150892167 | - |
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Fusion Gene ORF analysis for NSD1-FAT2 |
| Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| ORF | Henst | Tenst | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| In-frame | ENST00000347982 | ENST00000261800 | NSD1 | chr5 | 176675325 | + | FAT2 | chr5 | 150892167 | - |
| In-frame | ENST00000354179 | ENST00000261800 | NSD1 | chr5 | 176675325 | + | FAT2 | chr5 | 150892167 | - |
| In-frame | ENST00000361032 | ENST00000261800 | NSD1 | chr5 | 176675325 | + | FAT2 | chr5 | 150892167 | - |
| In-frame | ENST00000439151 | ENST00000261800 | NSD1 | chr5 | 176675325 | + | FAT2 | chr5 | 150892167 | - |
| intron-3CDS | ENST00000511258 | ENST00000261800 | NSD1 | chr5 | 176675325 | + | FAT2 | chr5 | 150892167 | - |
| ORFfinder result based on the fusion transcript sequence of in-frame fusion genes. |
| Henst | Tenst | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand | Seq length (transcript) | BP loci (transcript) | Predicted start (transcript) | Predicted stop (transcript) | Seq length (amino acids) |
| ENST00000354179 | NSD1 | chr5 | 176675325 | + | ENST00000261800 | FAT2 | chr5 | 150892167 | - | 7052 | 3994 | 160 | 5580 | 1806 |
| ENST00000439151 | NSD1 | chr5 | 176675325 | + | ENST00000261800 | FAT2 | chr5 | 150892167 | - | 7744 | 4686 | 45 | 6272 | 2075 |
| ENST00000347982 | NSD1 | chr5 | 176675325 | + | ENST00000261800 | FAT2 | chr5 | 150892167 | - | 6993 | 3935 | 101 | 5521 | 1806 |
| ENST00000361032 | NSD1 | chr5 | 176675325 | + | ENST00000261800 | FAT2 | chr5 | 150892167 | - | 7390 | 4332 | 0 | 5918 | 1972 |
| DeepORF prediction of the coding potential based on the fusion transcript sequence of in-frame fusion genes. DeepORF is a coding potential classifier based on convolutional neural network by comparing the real Ribo-seq data. If the no-coding score < 0.5 and coding score > 0.5, then the in-frame fusion transcript is predicted as being likely translated. |
| Henst | Tenst | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand | No-coding score | Coding score |
| ENST00000354179 | ENST00000261800 | NSD1 | chr5 | 176675325 | + | FAT2 | chr5 | 150892167 | - | 0.000526857 | 0.99947315 |
| ENST00000439151 | ENST00000261800 | NSD1 | chr5 | 176675325 | + | FAT2 | chr5 | 150892167 | - | 0.000451958 | 0.999548 |
| ENST00000347982 | ENST00000261800 | NSD1 | chr5 | 176675325 | + | FAT2 | chr5 | 150892167 | - | 0.000493382 | 0.9995066 |
| ENST00000361032 | ENST00000261800 | NSD1 | chr5 | 176675325 | + | FAT2 | chr5 | 150892167 | - | 0.000454954 | 0.99954504 |
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Fusion Genomic Features for NSD1-FAT2 |
| FusionAI prediction of the potential fusion gene breakpoint based on the pre-mature RNA sequence context (+/- 5kb of individual partner genes, total 20kb length sequence). FusionAI is a fusion gene breakpoint classifier based on convolutional neural network by comparing the fusion positive and negative sequence context of ~ 20K fusion gene data. From here, we can have the relative potentency of the 20K genomic sequence how individual sequnce will be likely used as the gene fusion breakpoints. |
| Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand | 1-p | p (fusion gene breakpoint) |
| Distribution of 44 human genomic features loci across 20kb length fusion breakpoint regions. We integrated a total of 44 different types of human genomic feature loci information across five big categories including virus integration sites, repeats, structural variants, chromatin states, and gene expression regulation. More details are in help page. |
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| Distribution of 44 human genomic features loci across 20kb length fusion breakpoint regions that are ovelapped with the top 1% feature importance score regions. More details are in help page. |
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Fusion Protein Features for NSD1-FAT2 |
| Four levels of functional features of fusion genes Go to FGviewer search page for the most frequent breakpoint (https://ccsmweb.uth.edu/FGviewer/chr5:176675325/chr5:150892167) - FGviewer provides the online visualization of the retention search of the protein functional features across DNA, RNA, protein, and pathological levels. - How to search 1. Put your fusion gene symbol. 2. Press the tab key until there will be shown the breakpoint information filled. 4. Go down and press 'Search' tab twice. 4. Go down to have the hyperlink of the search result. 5. Click the hyperlink. 6. See the FGviewer result for your fusion gene. |
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| Main function of each fusion partner protein. (from UniProt) |
| Hgene | Tgene |
| . | FAT2 |
| FUNCTION: Transcriptional activator which is required for calcium-dependent dendritic growth and branching in cortical neurons. Recruits CREB-binding protein (CREBBP) to nuclear bodies. Component of the CREST-BRG1 complex, a multiprotein complex that regulates promoter activation by orchestrating a calcium-dependent release of a repressor complex and a recruitment of an activator complex. In resting neurons, transcription of the c-FOS promoter is inhibited by BRG1-dependent recruitment of a phospho-RB1-HDAC1 repressor complex. Upon calcium influx, RB1 is dephosphorylated by calcineurin, which leads to release of the repressor complex. At the same time, there is increased recruitment of CREBBP to the promoter by a CREST-dependent mechanism, which leads to transcriptional activation. The CREST-BRG1 complex also binds to the NR2B promoter, and activity-dependent induction of NR2B expression involves a release of HDAC1 and recruitment of CREBBP (By similarity). {ECO:0000250}. | FUNCTION: Involved in the regulation of cell migration (PubMed:18534823). May be involved in mediating the organization of the parallel fibers of granule cells during cerebellar development (By similarity). {ECO:0000250|UniProtKB:O88277, ECO:0000269|PubMed:18534823}. |
| Retention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at * Minus value of BPloci means that the break pointn is located before the CDS. |
| - In-frame and retained protein feature among the 13 regional features. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Protein feature | Protein feature note |
| Hgene | NSD1 | chr5:176675325 | chr5:150892167 | ENST00000347982 | + | 12 | 24 | 323_388 | 1278 | 2428.0 | Domain | PWWP 1 |
| Hgene | NSD1 | chr5:176675325 | chr5:150892167 | ENST00000354179 | + | 12 | 24 | 323_388 | 1278 | 2428.0 | Domain | PWWP 1 |
| Hgene | NSD1 | chr5:176675325 | chr5:150892167 | ENST00000361032 | + | 8 | 20 | 323_388 | 1444 | 2594.0 | Domain | PWWP 1 |
| Hgene | NSD1 | chr5:176675325 | chr5:150892167 | ENST00000439151 | + | 11 | 23 | 323_388 | 1547 | 2697.0 | Domain | PWWP 1 |
| Tgene | FAT2 | chr5:176675325 | chr5:150892167 | ENST00000261800 | 18 | 23 | 3947_3984 | 3821 | 4350.0 | Domain | EGF-like 1 | |
| Tgene | FAT2 | chr5:176675325 | chr5:150892167 | ENST00000261800 | 18 | 23 | 3986_4022 | 3821 | 4350.0 | Domain | EGF-like 2 | |
| Tgene | FAT2 | chr5:176675325 | chr5:150892167 | ENST00000261800 | 18 | 23 | 4070_4349 | 3821 | 4350.0 | Topological domain | Cytoplasmic | |
| Tgene | FAT2 | chr5:176675325 | chr5:150892167 | ENST00000261800 | 18 | 23 | 4049_4069 | 3821 | 4350.0 | Transmembrane | Helical |
| - In-frame and not-retained protein feature among the 13 regional features. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Protein feature | Protein feature note |
| Hgene | NSD1 | chr5:176675325 | chr5:150892167 | ENST00000347982 | + | 12 | 24 | 2207_2421 | 1278 | 2428.0 | Compositional bias | Note=Pro-rich |
| Hgene | NSD1 | chr5:176675325 | chr5:150892167 | ENST00000354179 | + | 12 | 24 | 2207_2421 | 1278 | 2428.0 | Compositional bias | Note=Pro-rich |
| Hgene | NSD1 | chr5:176675325 | chr5:150892167 | ENST00000361032 | + | 8 | 20 | 2207_2421 | 1444 | 2594.0 | Compositional bias | Note=Pro-rich |
| Hgene | NSD1 | chr5:176675325 | chr5:150892167 | ENST00000439151 | + | 11 | 23 | 2207_2421 | 1547 | 2697.0 | Compositional bias | Note=Pro-rich |
| Hgene | NSD1 | chr5:176675325 | chr5:150892167 | ENST00000347982 | + | 12 | 24 | 1756_1818 | 1278 | 2428.0 | Domain | PWWP 2 |
| Hgene | NSD1 | chr5:176675325 | chr5:150892167 | ENST00000347982 | + | 12 | 24 | 1890_1940 | 1278 | 2428.0 | Domain | AWS |
| Hgene | NSD1 | chr5:176675325 | chr5:150892167 | ENST00000347982 | + | 12 | 24 | 1942_2059 | 1278 | 2428.0 | Domain | SET |
| Hgene | NSD1 | chr5:176675325 | chr5:150892167 | ENST00000347982 | + | 12 | 24 | 2066_2082 | 1278 | 2428.0 | Domain | Post-SET |
| Hgene | NSD1 | chr5:176675325 | chr5:150892167 | ENST00000354179 | + | 12 | 24 | 1756_1818 | 1278 | 2428.0 | Domain | PWWP 2 |
| Hgene | NSD1 | chr5:176675325 | chr5:150892167 | ENST00000354179 | + | 12 | 24 | 1890_1940 | 1278 | 2428.0 | Domain | AWS |
| Hgene | NSD1 | chr5:176675325 | chr5:150892167 | ENST00000354179 | + | 12 | 24 | 1942_2059 | 1278 | 2428.0 | Domain | SET |
| Hgene | NSD1 | chr5:176675325 | chr5:150892167 | ENST00000354179 | + | 12 | 24 | 2066_2082 | 1278 | 2428.0 | Domain | Post-SET |
| Hgene | NSD1 | chr5:176675325 | chr5:150892167 | ENST00000361032 | + | 8 | 20 | 1756_1818 | 1444 | 2594.0 | Domain | PWWP 2 |
| Hgene | NSD1 | chr5:176675325 | chr5:150892167 | ENST00000361032 | + | 8 | 20 | 1890_1940 | 1444 | 2594.0 | Domain | AWS |
| Hgene | NSD1 | chr5:176675325 | chr5:150892167 | ENST00000361032 | + | 8 | 20 | 1942_2059 | 1444 | 2594.0 | Domain | SET |
| Hgene | NSD1 | chr5:176675325 | chr5:150892167 | ENST00000361032 | + | 8 | 20 | 2066_2082 | 1444 | 2594.0 | Domain | Post-SET |
| Hgene | NSD1 | chr5:176675325 | chr5:150892167 | ENST00000439151 | + | 11 | 23 | 1756_1818 | 1547 | 2697.0 | Domain | PWWP 2 |
| Hgene | NSD1 | chr5:176675325 | chr5:150892167 | ENST00000439151 | + | 11 | 23 | 1890_1940 | 1547 | 2697.0 | Domain | AWS |
| Hgene | NSD1 | chr5:176675325 | chr5:150892167 | ENST00000439151 | + | 11 | 23 | 1942_2059 | 1547 | 2697.0 | Domain | SET |
| Hgene | NSD1 | chr5:176675325 | chr5:150892167 | ENST00000439151 | + | 11 | 23 | 2066_2082 | 1547 | 2697.0 | Domain | Post-SET |
| Hgene | NSD1 | chr5:176675325 | chr5:150892167 | ENST00000347982 | + | 12 | 24 | 1952_1954 | 1278 | 2428.0 | Region | Note=S-adenosyl-L-methionine binding |
| Hgene | NSD1 | chr5:176675325 | chr5:150892167 | ENST00000347982 | + | 12 | 24 | 1994_1997 | 1278 | 2428.0 | Region | Note=S-adenosyl-L-methionine binding |
| Hgene | NSD1 | chr5:176675325 | chr5:150892167 | ENST00000347982 | + | 12 | 24 | 2020_2021 | 1278 | 2428.0 | Region | Note=S-adenosyl-L-methionine binding |
| Hgene | NSD1 | chr5:176675325 | chr5:150892167 | ENST00000347982 | + | 12 | 24 | 2060_2066 | 1278 | 2428.0 | Region | Note=Inhibits enzyme activity in the absence of bound histone |
| Hgene | NSD1 | chr5:176675325 | chr5:150892167 | ENST00000354179 | + | 12 | 24 | 1952_1954 | 1278 | 2428.0 | Region | Note=S-adenosyl-L-methionine binding |
| Hgene | NSD1 | chr5:176675325 | chr5:150892167 | ENST00000354179 | + | 12 | 24 | 1994_1997 | 1278 | 2428.0 | Region | Note=S-adenosyl-L-methionine binding |
| Hgene | NSD1 | chr5:176675325 | chr5:150892167 | ENST00000354179 | + | 12 | 24 | 2020_2021 | 1278 | 2428.0 | Region | Note=S-adenosyl-L-methionine binding |
| Hgene | NSD1 | chr5:176675325 | chr5:150892167 | ENST00000354179 | + | 12 | 24 | 2060_2066 | 1278 | 2428.0 | Region | Note=Inhibits enzyme activity in the absence of bound histone |
| Hgene | NSD1 | chr5:176675325 | chr5:150892167 | ENST00000361032 | + | 8 | 20 | 1952_1954 | 1444 | 2594.0 | Region | Note=S-adenosyl-L-methionine binding |
| Hgene | NSD1 | chr5:176675325 | chr5:150892167 | ENST00000361032 | + | 8 | 20 | 1994_1997 | 1444 | 2594.0 | Region | Note=S-adenosyl-L-methionine binding |
| Hgene | NSD1 | chr5:176675325 | chr5:150892167 | ENST00000361032 | + | 8 | 20 | 2020_2021 | 1444 | 2594.0 | Region | Note=S-adenosyl-L-methionine binding |
| Hgene | NSD1 | chr5:176675325 | chr5:150892167 | ENST00000361032 | + | 8 | 20 | 2060_2066 | 1444 | 2594.0 | Region | Note=Inhibits enzyme activity in the absence of bound histone |
| Hgene | NSD1 | chr5:176675325 | chr5:150892167 | ENST00000439151 | + | 11 | 23 | 1952_1954 | 1547 | 2697.0 | Region | Note=S-adenosyl-L-methionine binding |
| Hgene | NSD1 | chr5:176675325 | chr5:150892167 | ENST00000439151 | + | 11 | 23 | 1994_1997 | 1547 | 2697.0 | Region | Note=S-adenosyl-L-methionine binding |
| Hgene | NSD1 | chr5:176675325 | chr5:150892167 | ENST00000439151 | + | 11 | 23 | 2020_2021 | 1547 | 2697.0 | Region | Note=S-adenosyl-L-methionine binding |
| Hgene | NSD1 | chr5:176675325 | chr5:150892167 | ENST00000439151 | + | 11 | 23 | 2060_2066 | 1547 | 2697.0 | Region | Note=Inhibits enzyme activity in the absence of bound histone |
| Hgene | NSD1 | chr5:176675325 | chr5:150892167 | ENST00000347982 | + | 12 | 24 | 1543_1589 | 1278 | 2428.0 | Zinc finger | PHD-type 1 |
| Hgene | NSD1 | chr5:176675325 | chr5:150892167 | ENST00000347982 | + | 12 | 24 | 1590_1646 | 1278 | 2428.0 | Zinc finger | PHD-type 2 |
| Hgene | NSD1 | chr5:176675325 | chr5:150892167 | ENST00000347982 | + | 12 | 24 | 1707_1751 | 1278 | 2428.0 | Zinc finger | PHD-type 3 |
| Hgene | NSD1 | chr5:176675325 | chr5:150892167 | ENST00000347982 | + | 12 | 24 | 2118_2165 | 1278 | 2428.0 | Zinc finger | PHD-type 4%3B atypical |
| Hgene | NSD1 | chr5:176675325 | chr5:150892167 | ENST00000354179 | + | 12 | 24 | 1543_1589 | 1278 | 2428.0 | Zinc finger | PHD-type 1 |
| Hgene | NSD1 | chr5:176675325 | chr5:150892167 | ENST00000354179 | + | 12 | 24 | 1590_1646 | 1278 | 2428.0 | Zinc finger | PHD-type 2 |
| Hgene | NSD1 | chr5:176675325 | chr5:150892167 | ENST00000354179 | + | 12 | 24 | 1707_1751 | 1278 | 2428.0 | Zinc finger | PHD-type 3 |
| Hgene | NSD1 | chr5:176675325 | chr5:150892167 | ENST00000354179 | + | 12 | 24 | 2118_2165 | 1278 | 2428.0 | Zinc finger | PHD-type 4%3B atypical |
| Hgene | NSD1 | chr5:176675325 | chr5:150892167 | ENST00000361032 | + | 8 | 20 | 1543_1589 | 1444 | 2594.0 | Zinc finger | PHD-type 1 |
| Hgene | NSD1 | chr5:176675325 | chr5:150892167 | ENST00000361032 | + | 8 | 20 | 1590_1646 | 1444 | 2594.0 | Zinc finger | PHD-type 2 |
| Hgene | NSD1 | chr5:176675325 | chr5:150892167 | ENST00000361032 | + | 8 | 20 | 1707_1751 | 1444 | 2594.0 | Zinc finger | PHD-type 3 |
| Hgene | NSD1 | chr5:176675325 | chr5:150892167 | ENST00000361032 | + | 8 | 20 | 2118_2165 | 1444 | 2594.0 | Zinc finger | PHD-type 4%3B atypical |
| Hgene | NSD1 | chr5:176675325 | chr5:150892167 | ENST00000439151 | + | 11 | 23 | 1543_1589 | 1547 | 2697.0 | Zinc finger | PHD-type 1 |
| Hgene | NSD1 | chr5:176675325 | chr5:150892167 | ENST00000439151 | + | 11 | 23 | 1590_1646 | 1547 | 2697.0 | Zinc finger | PHD-type 2 |
| Hgene | NSD1 | chr5:176675325 | chr5:150892167 | ENST00000439151 | + | 11 | 23 | 1707_1751 | 1547 | 2697.0 | Zinc finger | PHD-type 3 |
| Hgene | NSD1 | chr5:176675325 | chr5:150892167 | ENST00000439151 | + | 11 | 23 | 2118_2165 | 1547 | 2697.0 | Zinc finger | PHD-type 4%3B atypical |
| Tgene | FAT2 | chr5:176675325 | chr5:150892167 | ENST00000261800 | 18 | 23 | 3297_3302 | 3821 | 4350.0 | Compositional bias | Note=Poly-Ser | |
| Tgene | FAT2 | chr5:176675325 | chr5:150892167 | ENST00000261800 | 18 | 23 | 1033_1137 | 3821 | 4350.0 | Domain | Cadherin 9 | |
| Tgene | FAT2 | chr5:176675325 | chr5:150892167 | ENST00000261800 | 18 | 23 | 1138_1242 | 3821 | 4350.0 | Domain | Cadherin 10 | |
| Tgene | FAT2 | chr5:176675325 | chr5:150892167 | ENST00000261800 | 18 | 23 | 1243_1346 | 3821 | 4350.0 | Domain | Cadherin 11 | |
| Tgene | FAT2 | chr5:176675325 | chr5:150892167 | ENST00000261800 | 18 | 23 | 1350_1448 | 3821 | 4350.0 | Domain | Cadherin 12 | |
| Tgene | FAT2 | chr5:176675325 | chr5:150892167 | ENST00000261800 | 18 | 23 | 1449_1555 | 3821 | 4350.0 | Domain | Cadherin 13 | |
| Tgene | FAT2 | chr5:176675325 | chr5:150892167 | ENST00000261800 | 18 | 23 | 149_256 | 3821 | 4350.0 | Domain | Cadherin 2 | |
| Tgene | FAT2 | chr5:176675325 | chr5:150892167 | ENST00000261800 | 18 | 23 | 1556_1660 | 3821 | 4350.0 | Domain | Cadherin 14 | |
| Tgene | FAT2 | chr5:176675325 | chr5:150892167 | ENST00000261800 | 18 | 23 | 1661_1758 | 3821 | 4350.0 | Domain | Cadherin 15 | |
| Tgene | FAT2 | chr5:176675325 | chr5:150892167 | ENST00000261800 | 18 | 23 | 1759_1872 | 3821 | 4350.0 | Domain | Cadherin 16 | |
| Tgene | FAT2 | chr5:176675325 | chr5:150892167 | ENST00000261800 | 18 | 23 | 1969_2070 | 3821 | 4350.0 | Domain | Cadherin 17 | |
| Tgene | FAT2 | chr5:176675325 | chr5:150892167 | ENST00000261800 | 18 | 23 | 2071_2171 | 3821 | 4350.0 | Domain | Cadherin 18 | |
| Tgene | FAT2 | chr5:176675325 | chr5:150892167 | ENST00000261800 | 18 | 23 | 2172_2272 | 3821 | 4350.0 | Domain | Cadherin 19 | |
| Tgene | FAT2 | chr5:176675325 | chr5:150892167 | ENST00000261800 | 18 | 23 | 2273_2379 | 3821 | 4350.0 | Domain | Cadherin 20 | |
| Tgene | FAT2 | chr5:176675325 | chr5:150892167 | ENST00000261800 | 18 | 23 | 2380_2481 | 3821 | 4350.0 | Domain | Cadherin 21 | |
| Tgene | FAT2 | chr5:176675325 | chr5:150892167 | ENST00000261800 | 18 | 23 | 2482_2585 | 3821 | 4350.0 | Domain | Cadherin 22 | |
| Tgene | FAT2 | chr5:176675325 | chr5:150892167 | ENST00000261800 | 18 | 23 | 2586_2691 | 3821 | 4350.0 | Domain | Cadherin 23 | |
| Tgene | FAT2 | chr5:176675325 | chr5:150892167 | ENST00000261800 | 18 | 23 | 2692_2797 | 3821 | 4350.0 | Domain | Cadherin 24 | |
| Tgene | FAT2 | chr5:176675325 | chr5:150892167 | ENST00000261800 | 18 | 23 | 2798_2906 | 3821 | 4350.0 | Domain | Cadherin 25 | |
| Tgene | FAT2 | chr5:176675325 | chr5:150892167 | ENST00000261800 | 18 | 23 | 2907_3011 | 3821 | 4350.0 | Domain | Cadherin 26 | |
| Tgene | FAT2 | chr5:176675325 | chr5:150892167 | ENST00000261800 | 18 | 23 | 3012_3113 | 3821 | 4350.0 | Domain | Cadherin 27 | |
| Tgene | FAT2 | chr5:176675325 | chr5:150892167 | ENST00000261800 | 18 | 23 | 3114_3218 | 3821 | 4350.0 | Domain | Cadherin 28 | |
| Tgene | FAT2 | chr5:176675325 | chr5:150892167 | ENST00000261800 | 18 | 23 | 3219_3321 | 3821 | 4350.0 | Domain | Cadherin 29 | |
| Tgene | FAT2 | chr5:176675325 | chr5:150892167 | ENST00000261800 | 18 | 23 | 3322_3426 | 3821 | 4350.0 | Domain | Cadherin 30 | |
| Tgene | FAT2 | chr5:176675325 | chr5:150892167 | ENST00000261800 | 18 | 23 | 3427_3531 | 3821 | 4350.0 | Domain | Cadherin 31 | |
| Tgene | FAT2 | chr5:176675325 | chr5:150892167 | ENST00000261800 | 18 | 23 | 34_148 | 3821 | 4350.0 | Domain | Cadherin 1 | |
| Tgene | FAT2 | chr5:176675325 | chr5:150892167 | ENST00000261800 | 18 | 23 | 3532_3642 | 3821 | 4350.0 | Domain | Cadherin 32 | |
| Tgene | FAT2 | chr5:176675325 | chr5:150892167 | ENST00000261800 | 18 | 23 | 363_458 | 3821 | 4350.0 | Domain | Cadherin 3 | |
| Tgene | FAT2 | chr5:176675325 | chr5:150892167 | ENST00000261800 | 18 | 23 | 3773_3944 | 3821 | 4350.0 | Domain | Laminin G-like | |
| Tgene | FAT2 | chr5:176675325 | chr5:150892167 | ENST00000261800 | 18 | 23 | 459_564 | 3821 | 4350.0 | Domain | Cadherin 4 | |
| Tgene | FAT2 | chr5:176675325 | chr5:150892167 | ENST00000261800 | 18 | 23 | 565_669 | 3821 | 4350.0 | Domain | Cadherin 5 | |
| Tgene | FAT2 | chr5:176675325 | chr5:150892167 | ENST00000261800 | 18 | 23 | 716_820 | 3821 | 4350.0 | Domain | Cadherin 6 | |
| Tgene | FAT2 | chr5:176675325 | chr5:150892167 | ENST00000261800 | 18 | 23 | 821_925 | 3821 | 4350.0 | Domain | Cadherin 7 | |
| Tgene | FAT2 | chr5:176675325 | chr5:150892167 | ENST00000261800 | 18 | 23 | 926_1032 | 3821 | 4350.0 | Domain | Cadherin 8 | |
| Tgene | FAT2 | chr5:176675325 | chr5:150892167 | ENST00000261800 | 18 | 23 | 19_4048 | 3821 | 4350.0 | Topological domain | Extracellular |
Top |
Fusion Gene Sequence for NSD1-FAT2 |
| For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. To have fusion amino acid sequence, we ran ORFfinder and chose the longest ORF among the all predicted ones. |
| >60418_60418_1_NSD1-FAT2_NSD1_chr5_176675325_ENST00000347982_FAT2_chr5_150892167_ENST00000261800_length(transcript)=6993nt_BP=3935nt CCTCCGCCTCCCCTCAGGTTGATGCCGGCCCAGGATGGATCAGACCTGTGAACTACCCAGAAGAAATTGTCTGCTGCCCTTTTCCAATCC AGTGAATTTAGATGCCCCTGAAGACAAGGACAGCCCTTTCGGATGATCCAGATTCCAGTACCAGTACATTAGGAAACATGCTAGAATTAC CTGGAACTTCATCATCATCTACTTCACAGGAATTGCCATTTTGTCAACCTAAGAAAAAGTCTACGCCACTGAAGTATGAAGTTGGAGATC TCATCTGGGCAAAATTCAAGAGACGCCCATGGTGGCCCTGCAGGATTTGTTCTGATCCGTTGATTAACACACATTCAAAAATGAAAGTTT CCAACCGGAGGCCCTATCGGCAGTACTACGTGGAGGCTTTTGGAGATCCTTCTGAGAGAGCCTGGGTGGCTGGAAAAGCAATCGTCATGT TTGAAGGCAGACATCAATTCGAAGAGCTACCTGTCCTTAGGAGAAGAGGGAAACAGAAAGAAAAAGGATATAGGCATAAGGTTCCTCAGA AAATTTTGAGTAAATGGGAAGCCAGTGTTGGACTTGCAGAACAGTATGATGTTCCCAAGGGGTCAAAGAACCGAAAATGTATTCCTGGTT CAATCAAGTTGGACAGTGAAGAAGATATGCCATTTGAAGACTGCACAAATGATCCTGAGTCAGAACATGACCTGTTGCTTAATGGCTGTT TGAAATCACTGGCTTTTGATTCTGAACATTCTGCAGATGAGAAGGAAAAGCCTTGCGCTAAATCTCGAGCCAGAAAGAGCTCTGATAATC CAAAAAGGACTAGTGTGAAAAAGGGCCACATACAATTTGAAGCACATAAAGATGAACGGAGGGGAAAGATTCCAGAGAACCTTGGCCTAA ACTTTATCTCTGGGGATATATCTGATACGCAGGCCTCTAATGAACTTTCCAGGATAGCAAATAGCCTCACAGGGTCCAACACTGCCCCAG GAAGTTTTCTGTTTTCTTCCTGTGGAAAAAACACTGCAAAGAAAGAATTTGAGACTTCAAATGGTGACTCTTTATTGGGCTTGCCTGAGG GTGCTTTGATCTCAAAGTGTTCTCGAGAGAAGAATAAACCCCAACGAAGCCTGGTGTGTGGTTCAAAAGTGAAGCTCTGCTATATTGGAG CAGGTGATGAGGAAAAGCGAAGTGATTCCATTAGTATCTGTACCACTTCTGATGATGGAAGCAGTGACCTGGATCCCATAGAACACAGCT CAGAGTCTGATAACAGTGTCCTTGAAATTCCAGATGCTTTCGATAGAACAGAGAACATGTTATCTATGCAGAAAAATGAAAAGATAAAGT ATTCTAGGTTTGCTGCCACAAACACTAGGGTAAAAGCAAAACAGAAGCCTCTCATTAGTAACTCACATACAGACCACTTAATGGGTTGTA CTAAGAGTGCAGAGCCTGGAACCGAGACGTCTCAGGTTAATCTCTCTGATCTGAAGGCATCTACTCTTGTTCACAAACCCCAGTCAGATT TTACAAATGATGCTCTCTCTCCAAAATTCAACCTGTCATCAAGCATATCCAGTGAGAACTCGTTAATAAAGGGTGGGGCAGCAAATCAAG CTCTATTACATTCGAAAAGCAAACAGCCCAAGTTCCGAAGTATAAAGTGCAAACACAAAGAAAATCCAGTTATGGCAGAACCCCCAGTTA TAAATGAGGAGTGCAGTTTGAAATGCTGCTCTTCTGATACCAAAGGCTCTCCTTTGGCCAGCATTTCTAAAAGTGGGAAAGTGGATGGTC TAAAACTACTGAACAATATGCATGAGAAAACCAGGGATTCAAGTGACATAGAAACAGCAGTGGTGAAACATGTTTTATCCGAGTTGAAGG AACTCTCTTACAGATCCTTAGGTGAGGATGTCAGTGACTCTGGAACATCAAAGCCATCAAAACCATTACTTTTCTCTTCTGCTTCTAGTC AGAATCACATACCTATTGAACCAGACTACAAATTCAGTACATTGCTAATGATGTTGAAAGATATGCATGATAGTAAGACGAAGGAGCAGC GGTTGATGACTGCTCAAAACCTGGTCTCTTACCGGAGTCCTGGTCGTGGGGACTGTTCTACTAATAGTCCTGTAGGAGTCTCTAAGGTTT TGGTTTCAGGAGGCTCCACACACAATTCAGAGAAAAAGGGAGATGGCACTCAGAACTCCGCCAATCCTAGCCCTAGTGGGGGTGACTCTG CATTATCTGGCGAGTTGTCTGCTTCCCTACCTGGCTTACTGTCCGACAAGAGAGACCTCCCTGCTTCTGGTAAAAGTCGTTCAGACTGTG TTACTAGGCGCAACTGTGGACGATCAAAGCCTTCATCCAAATTGCGAGATGCTTTTTCAGCCCAAATGGTAAAGAACACAGTGAACCGTA AAGCCTTAAAGACCGAGCGCAAAAGAAAACTGAATCAGCTTCCAAGTGTGACTCTTGATGCTGTACTGCAGGGAGACCGAGAACGTGGAG GTTCATTGAGAGGTGGGGCAGAAGATCCTAGTAAAGAGGATCCCCTTCAGATAATGGGCCACTTAACAAGTGAAGATGGTGACCATTTTT CTGATGTGCATTTCGATAGCAAGGTTAAGCAATCTGATCCTGGTAAAATTTCTGAAAAAGGACTCTCTTTTGAAAACGGAAAAGGCCCAG AGCTGGACTCTGTAATGAACAGTGAGAATGATGAACTCAATGGTGTAAATCAAGTGGTGCCTAAAAAGCGGTGGCAGCGTTTAAACCAAA GGCGCACTAAACCTCGTAAGCGCATGAACAGATTTAAAGAGAAAGAAAACTCTGAGTGTGCCTTTAGGGTCTTACTTCCTAGTGACCCTG TGCAGGAGGGGCGGGATGAGTTTCCAGAGCATAGAACTCCTTCAGCAAGCATACTTGAGGAACCACTGACAGAGCAAAATCATGCTGACT GCTTAGATTCAGCTGGGCCACGGTTAAATGTTTGTGATAAATCCAGTGCCAGCATTGGTGACATGGAAAAGGAGCCAGGAATTCCCAGTT TGACACCACAGGCTGAGCTCCCTGAACCAGCTGTGCGGTCAGAGAAGAAACGCCTTAGGAAGCCAAGCAAGTGGCTTTTGGAATATACAG AAGAATATGATCAGATATTTGCTCCTAAGAAAAAACAAAAGAAGGTACAGGAGCAGGTGCACAAGGTAAGTTCCCGCTGTGAAGAGGAAA GCCTTCTAGCCCGAGGTCGATCTAGTGCTCAGAACAAGCAGGTGGACGAGAATTCTTTGATTTCAACCAAAGAAGAGCCTCCAGTTCTTG AAAGGGAGGCTCCGTTTTTGGAGGGCCCCTTGGCTCAGTCAGAACTTGGAGGTGGACATGCTGAGTTGCCGCAGCTGACCTTGTCTGTGC CTGTGGCTCCGGAAGTCTCTCCACGGCCTGCCCTTGAGTCTGAGGAATTGCTAGTTAAAACGCCAGGAAATTATGAAAGTAAACGTCAAA GAAAACCAACTAAGAAACTTCTTGAATCCAATGATTTAGACCCTGGATTTATGCCCAAGAAGGGGGACCTTGGCCTTTCTAAAAAGTGCT ATGAAGCTGGTCACCTGGAGAATGGCATAACTGAATCTTGTGCCACATCTTATTCAAAAGATTTTGGTGGAGGCACTACCAAGATATTTG ACAAGCCAAGGAAGCGAAAACGACAGAGGCATGCTGCAGCCAAGATGCAGTGTAAAAAAGTGAAAAATGATGACTCGTCAAAAGAGATTC CAGGCTCAGAGGGAGAACTAATGCCTCACAGGACGGCCACAAGCCCCAAGGAGACTGTTGAGGAAGGTGTAGAACACGATCCCGGGATGC CTGCCTCTAAAAAAATGCAGGGTGAACGCGGTGGAGGAGCTGCACTCAAGGAGAATGTCTGTCAGCTGGCCAGTGGAGTGCCCCAGCTGG AATACCACTGTCTGGGTGGTTTCTATGGAAACCTTTCCTCCCAGCGCCATGTGAATGACCACGAGTGGCACTCCATCCTGGTGGAGGAGA TGGACGCTTCCATTCGCCTGATGGTTGACAGCATGGGCAACACCTCCCTTGTGGTCCCAGAGAACTGCCGTGGTCTGAGGCCCGAAAGGC ACCTCTTGCTGGGCGGCCTCATTCTGTTGCATTCTTCCTCGAATGTCTCCCAGGGCTTTGAAGGCTGCCTGGATGCTGTCGTGGTCAACG AAGAGGCTCTAGATCTGCTGGCCCCTGGCAAGACGGTGGCAGGCTTGCTGGAGACACAAGCCCTCACCCAGTGCTGCCTCCACAGTGACT ACTGCAGCCAGAACACATGCCTCAATGGTGGGAAGTGCTCATGGACCCATGGGGCAGGCTATGTCTGCAAATGTCCCCCACAGTTCTCTG GGAAGCACTGTGAACAAGGAAGGGAGAACTGTACTTTTGCACCCTGCCTGGAAGGTGGAACTTGCATCCTCTCCCCCAAAGGAGCTTCCT GTAACTGCCCTCATCCTTACACAGGAGACAGGTGTGAAATGGAGGCGAGGGGTTGTTCAGAAGGACACTGCCTAGTCACTCCCGAGATCC AAAGGGGGGACTGGGGGCAGCAGGAGTTACTGATCATCACAGTGGCCGTGGCGTTCATTATCATAAGCACTGTCGGGCTTCTCTTCTACT GCCGCCGTTGCAAGTCTCACAAGCCTGTGGCCATGGAGGACCCAGACCTCCTGGCCAGGAGTGTTGGTGTTGACACCCAAGCCATGCCTG CCATCGAGCTCAACCCATTGAGTGCCAGCTCCTGCAACAACCTCAACCAACCGGAACCCAGCAAGGCCTCTGTTCCAAATGAACTCGTCA CATTTGGACCCAATTCTAAGCAACGGCCAGTGGTCTGCAGTGTGCCCCCCAGACTCCCGCCAGCTGCGGTCCCTTCCCACTCTGACAATG AGCCTGTCATTAAGAGAACCTGGTCCAGCGAGGAGATGGTGTACCCTGGCGGAGCCATGGTCTGGCCCCCTACTTACTCCAGGAACGAAC GCTGGGAATACCCCCACTCCGAAGTGACTCAGGGCCCTCTGCCGCCCTCGGCTCACCGCCACTCAACCCCAGTCGTGATGCCAGAGCCTA ATGGCCTCTATGGGGGCTTCCCCTTCCCCCTGGAGATGGAAAACAAGCGGGCACCTCTCCCACCCCGTTACAGCAACCAGAACCTGGAAG ATCTGATGCCCTCTCGGCCCCCTAGTCCCCGGGAGCGCCTGGTTGCCCCCTGTCTCAATGAGTACACGGCCATCAGCTACTACCACTCGC AGTTCCGGCAGGGAGGGGGAGGGCCCTGCCTGGCAGACGGGGGCTACAAGGGGGTGGGTATGCGCCTCAGCCGAGCTGGGCCCTCTTATG CTGTCTGTGAGGTGGAGGGGGCACCTCTTGCAGGCCAGGGCCAGCCCCGGGTGCCCCCCAACTATGAGGGCTCTGACATGGTGGAGAGTG ATTATGGCAGCTGTGAGGAGGTCATGTTCTAGCTTCCCATTCCCAGAGCAAGGCAGGCGGGAGGCCAAGGACTGGACTTGGCTTATTTCT TCCTGTCTCGTAGGGGGTGAGTTGAGTGTGGCTGGGAGAGTGGGAGGGAAGCCCTCAGCCCAGGCTGTTGTCCCTTGAAATGTGCTCTTC CAATCCCCCACCTAGTCCCTGAGGGTGGAGGGAAGCTGAGGATAGAGCTCCAGAAACAGCACTAGGGTCCCAGGAGAGGGGCATTTCTAG AGCAGTGACCCTGGAAAACCAGGAACAATTGACTCCCGGGGTGGGCGAGAGACAGGAGGGCTCCCTGATCTGCCGGCTCTCAGTCCCCGG GGCAGAGCCTGATTGACTGTGCTGGCTCAACTTCACCAAGATGCATTCTCATACCTGCCCACAGCTCCATTTTGGAGGCAGGCAGGTTGG TGCCTGACAGACAACCACTACGCGGGCCGTACAGAGGAGCTCTAGAGGGCTGCGTGGCATCCTCCTAGGGGCTGAGAGGTGAGCAGCAGG GGAGCGGGCACAGTCCCCTCTGCCCCTGCCTCAGTCGAGCACTCACTGTGTCTTTGTCAAGTGTCTGCTCCACGTCAGGCACTGTGCTTT GCACCGGGGAGAAAATGGTGATGGAGGGCAACAAGGACTCCGAGGAGCACCACCAGGCCTCGGGCCCCAGAGGTCCCACTCCTCAGCCTA CACGCAGAGGAACGGGCCCACCTCAGAGTCACACCACTGGCTGCCAGTCAGGGCCTGCCAGGAGTCTACACAGCTCTGAACCTTCTTTGT TAAAGAATTCAGACCTCATGGAACTCTGGGTTCTTCATCCCAAGTTTCCCAGGCACTTTTGGCCAAAGGAAGGAAGGAACTAATTCTTCA TTTTAAAAATTCTTAGGCACTTTTTGACCTTGCTGTCTGGATGAGTTTCCTCAATGGGATTTTTCTTCCCTAGACACAAGGAAGTCTGAA CTCCTATTTAGGGCCGGTTGGAAGCAGGGAGCTGGACCGCAGTGTCCAGGCTGGACACCTGCCATTGCCTCCTCTCCATTGCAGACGCCT GCCCATCAAGTATTACCTGCGGCGACTCAACCCTATGCATGGAGGGTCAATGTGGGCACATGTCTACACATGTGGGTGCCCATGGATAGT ACGTGTGTACACATGTGTAGAGTGTATGTAGCCAGGAGTGGTGGGGACCAGAAGCCTCTGTGGCCTTTGGTGACCTCACCACTCCCTCCC ACCCAGTCCCTCCCTCTGGTCCACTGCCTTTTCATATGTGTTGTTTCTGGAGACAGAAGTCAAAAGGAAGAGCAGTGGAGCCTTGCCCAC AGGGCTGCTGCTTCATGCGAGAGGGAGATGTGTGGGCGAGAGCCAATTTGTGTGAGTGGTTTGTGGCTGTGTGTGTGACTGTGAGTGTGA >60418_60418_1_NSD1-FAT2_NSD1_chr5_176675325_ENST00000347982_FAT2_chr5_150892167_ENST00000261800_length(amino acids)=1806AA_BP=1277 MPLKTRTALSDDPDSSTSTLGNMLELPGTSSSSTSQELPFCQPKKKSTPLKYEVGDLIWAKFKRRPWWPCRICSDPLINTHSKMKVSNRR PYRQYYVEAFGDPSERAWVAGKAIVMFEGRHQFEELPVLRRRGKQKEKGYRHKVPQKILSKWEASVGLAEQYDVPKGSKNRKCIPGSIKL DSEEDMPFEDCTNDPESEHDLLLNGCLKSLAFDSEHSADEKEKPCAKSRARKSSDNPKRTSVKKGHIQFEAHKDERRGKIPENLGLNFIS GDISDTQASNELSRIANSLTGSNTAPGSFLFSSCGKNTAKKEFETSNGDSLLGLPEGALISKCSREKNKPQRSLVCGSKVKLCYIGAGDE EKRSDSISICTTSDDGSSDLDPIEHSSESDNSVLEIPDAFDRTENMLSMQKNEKIKYSRFAATNTRVKAKQKPLISNSHTDHLMGCTKSA EPGTETSQVNLSDLKASTLVHKPQSDFTNDALSPKFNLSSSISSENSLIKGGAANQALLHSKSKQPKFRSIKCKHKENPVMAEPPVINEE CSLKCCSSDTKGSPLASISKSGKVDGLKLLNNMHEKTRDSSDIETAVVKHVLSELKELSYRSLGEDVSDSGTSKPSKPLLFSSASSQNHI PIEPDYKFSTLLMMLKDMHDSKTKEQRLMTAQNLVSYRSPGRGDCSTNSPVGVSKVLVSGGSTHNSEKKGDGTQNSANPSPSGGDSALSG ELSASLPGLLSDKRDLPASGKSRSDCVTRRNCGRSKPSSKLRDAFSAQMVKNTVNRKALKTERKRKLNQLPSVTLDAVLQGDRERGGSLR GGAEDPSKEDPLQIMGHLTSEDGDHFSDVHFDSKVKQSDPGKISEKGLSFENGKGPELDSVMNSENDELNGVNQVVPKKRWQRLNQRRTK PRKRMNRFKEKENSECAFRVLLPSDPVQEGRDEFPEHRTPSASILEEPLTEQNHADCLDSAGPRLNVCDKSSASIGDMEKEPGIPSLTPQ AELPEPAVRSEKKRLRKPSKWLLEYTEEYDQIFAPKKKQKKVQEQVHKVSSRCEEESLLARGRSSAQNKQVDENSLISTKEEPPVLEREA PFLEGPLAQSELGGGHAELPQLTLSVPVAPEVSPRPALESEELLVKTPGNYESKRQRKPTKKLLESNDLDPGFMPKKGDLGLSKKCYEAG HLENGITESCATSYSKDFGGGTTKIFDKPRKRKRQRHAAAKMQCKKVKNDDSSKEIPGSEGELMPHRTATSPKETVEEGVEHDPGMPASK KMQGERGGGAALKENVCQLASGVPQLEYHCLGGFYGNLSSQRHVNDHEWHSILVEEMDASIRLMVDSMGNTSLVVPENCRGLRPERHLLL GGLILLHSSSNVSQGFEGCLDAVVVNEEALDLLAPGKTVAGLLETQALTQCCLHSDYCSQNTCLNGGKCSWTHGAGYVCKCPPQFSGKHC EQGRENCTFAPCLEGGTCILSPKGASCNCPHPYTGDRCEMEARGCSEGHCLVTPEIQRGDWGQQELLIITVAVAFIIISTVGLLFYCRRC KSHKPVAMEDPDLLARSVGVDTQAMPAIELNPLSASSCNNLNQPEPSKASVPNELVTFGPNSKQRPVVCSVPPRLPPAAVPSHSDNEPVI KRTWSSEEMVYPGGAMVWPPTYSRNERWEYPHSEVTQGPLPPSAHRHSTPVVMPEPNGLYGGFPFPLEMENKRAPLPPRYSNQNLEDLMP SRPPSPRERLVAPCLNEYTAISYYHSQFRQGGGGPCLADGGYKGVGMRLSRAGPSYAVCEVEGAPLAGQGQPRVPPNYEGSDMVESDYGS -------------------------------------------------------------- >60418_60418_2_NSD1-FAT2_NSD1_chr5_176675325_ENST00000354179_FAT2_chr5_150892167_ENST00000261800_length(transcript)=7052nt_BP=3994nt GGCCGGGTAGGGGGTTCGCCTGCGGCCGCGTCTGCTCGGGGCCTGAGGCCTCGAAGACCCCAGCCCAAGCCCCCAGGTTGATGCCGGCCC AGGATGGATCAGACCTGTGAACTACCCAGAAGAAATTGTCTGCTGCCCTTTTCCAATCCAGTGAATTTAGATGCCCCTGAAGACAAGGAC AGCCCTTTCGGATGATCCAGATTCCAGTACCAGTACATTAGGAAACATGCTAGAATTACCTGGAACTTCATCATCATCTACTTCACAGGA ATTGCCATTTTGTCAACCTAAGAAAAAGTCTACGCCACTGAAGTATGAAGTTGGAGATCTCATCTGGGCAAAATTCAAGAGACGCCCATG GTGGCCCTGCAGGATTTGTTCTGATCCGTTGATTAACACACATTCAAAAATGAAAGTTTCCAACCGGAGGCCCTATCGGCAGTACTACGT GGAGGCTTTTGGAGATCCTTCTGAGAGAGCCTGGGTGGCTGGAAAAGCAATCGTCATGTTTGAAGGCAGACATCAATTCGAAGAGCTACC TGTCCTTAGGAGAAGAGGGAAACAGAAAGAAAAAGGATATAGGCATAAGGTTCCTCAGAAAATTTTGAGTAAATGGGAAGCCAGTGTTGG ACTTGCAGAACAGTATGATGTTCCCAAGGGGTCAAAGAACCGAAAATGTATTCCTGGTTCAATCAAGTTGGACAGTGAAGAAGATATGCC ATTTGAAGACTGCACAAATGATCCTGAGTCAGAACATGACCTGTTGCTTAATGGCTGTTTGAAATCACTGGCTTTTGATTCTGAACATTC TGCAGATGAGAAGGAAAAGCCTTGCGCTAAATCTCGAGCCAGAAAGAGCTCTGATAATCCAAAAAGGACTAGTGTGAAAAAGGGCCACAT ACAATTTGAAGCACATAAAGATGAACGGAGGGGAAAGATTCCAGAGAACCTTGGCCTAAACTTTATCTCTGGGGATATATCTGATACGCA GGCCTCTAATGAACTTTCCAGGATAGCAAATAGCCTCACAGGGTCCAACACTGCCCCAGGAAGTTTTCTGTTTTCTTCCTGTGGAAAAAA CACTGCAAAGAAAGAATTTGAGACTTCAAATGGTGACTCTTTATTGGGCTTGCCTGAGGGTGCTTTGATCTCAAAGTGTTCTCGAGAGAA GAATAAACCCCAACGAAGCCTGGTGTGTGGTTCAAAAGTGAAGCTCTGCTATATTGGAGCAGGTGATGAGGAAAAGCGAAGTGATTCCAT TAGTATCTGTACCACTTCTGATGATGGAAGCAGTGACCTGGATCCCATAGAACACAGCTCAGAGTCTGATAACAGTGTCCTTGAAATTCC AGATGCTTTCGATAGAACAGAGAACATGTTATCTATGCAGAAAAATGAAAAGATAAAGTATTCTAGGTTTGCTGCCACAAACACTAGGGT AAAAGCAAAACAGAAGCCTCTCATTAGTAACTCACATACAGACCACTTAATGGGTTGTACTAAGAGTGCAGAGCCTGGAACCGAGACGTC TCAGGTTAATCTCTCTGATCTGAAGGCATCTACTCTTGTTCACAAACCCCAGTCAGATTTTACAAATGATGCTCTCTCTCCAAAATTCAA CCTGTCATCAAGCATATCCAGTGAGAACTCGTTAATAAAGGGTGGGGCAGCAAATCAAGCTCTATTACATTCGAAAAGCAAACAGCCCAA GTTCCGAAGTATAAAGTGCAAACACAAAGAAAATCCAGTTATGGCAGAACCCCCAGTTATAAATGAGGAGTGCAGTTTGAAATGCTGCTC TTCTGATACCAAAGGCTCTCCTTTGGCCAGCATTTCTAAAAGTGGGAAAGTGGATGGTCTAAAACTACTGAACAATATGCATGAGAAAAC CAGGGATTCAAGTGACATAGAAACAGCAGTGGTGAAACATGTTTTATCCGAGTTGAAGGAACTCTCTTACAGATCCTTAGGTGAGGATGT CAGTGACTCTGGAACATCAAAGCCATCAAAACCATTACTTTTCTCTTCTGCTTCTAGTCAGAATCACATACCTATTGAACCAGACTACAA ATTCAGTACATTGCTAATGATGTTGAAAGATATGCATGATAGTAAGACGAAGGAGCAGCGGTTGATGACTGCTCAAAACCTGGTCTCTTA CCGGAGTCCTGGTCGTGGGGACTGTTCTACTAATAGTCCTGTAGGAGTCTCTAAGGTTTTGGTTTCAGGAGGCTCCACACACAATTCAGA GAAAAAGGGAGATGGCACTCAGAACTCCGCCAATCCTAGCCCTAGTGGGGGTGACTCTGCATTATCTGGCGAGTTGTCTGCTTCCCTACC TGGCTTACTGTCCGACAAGAGAGACCTCCCTGCTTCTGGTAAAAGTCGTTCAGACTGTGTTACTAGGCGCAACTGTGGACGATCAAAGCC TTCATCCAAATTGCGAGATGCTTTTTCAGCCCAAATGGTAAAGAACACAGTGAACCGTAAAGCCTTAAAGACCGAGCGCAAAAGAAAACT GAATCAGCTTCCAAGTGTGACTCTTGATGCTGTACTGCAGGGAGACCGAGAACGTGGAGGTTCATTGAGAGGTGGGGCAGAAGATCCTAG TAAAGAGGATCCCCTTCAGATAATGGGCCACTTAACAAGTGAAGATGGTGACCATTTTTCTGATGTGCATTTCGATAGCAAGGTTAAGCA ATCTGATCCTGGTAAAATTTCTGAAAAAGGACTCTCTTTTGAAAACGGAAAAGGCCCAGAGCTGGACTCTGTAATGAACAGTGAGAATGA TGAACTCAATGGTGTAAATCAAGTGGTGCCTAAAAAGCGGTGGCAGCGTTTAAACCAAAGGCGCACTAAACCTCGTAAGCGCATGAACAG ATTTAAAGAGAAAGAAAACTCTGAGTGTGCCTTTAGGGTCTTACTTCCTAGTGACCCTGTGCAGGAGGGGCGGGATGAGTTTCCAGAGCA TAGAACTCCTTCAGCAAGCATACTTGAGGAACCACTGACAGAGCAAAATCATGCTGACTGCTTAGATTCAGCTGGGCCACGGTTAAATGT TTGTGATAAATCCAGTGCCAGCATTGGTGACATGGAAAAGGAGCCAGGAATTCCCAGTTTGACACCACAGGCTGAGCTCCCTGAACCAGC TGTGCGGTCAGAGAAGAAACGCCTTAGGAAGCCAAGCAAGTGGCTTTTGGAATATACAGAAGAATATGATCAGATATTTGCTCCTAAGAA AAAACAAAAGAAGGTACAGGAGCAGGTGCACAAGGTAAGTTCCCGCTGTGAAGAGGAAAGCCTTCTAGCCCGAGGTCGATCTAGTGCTCA GAACAAGCAGGTGGACGAGAATTCTTTGATTTCAACCAAAGAAGAGCCTCCAGTTCTTGAAAGGGAGGCTCCGTTTTTGGAGGGCCCCTT GGCTCAGTCAGAACTTGGAGGTGGACATGCTGAGTTGCCGCAGCTGACCTTGTCTGTGCCTGTGGCTCCGGAAGTCTCTCCACGGCCTGC CCTTGAGTCTGAGGAATTGCTAGTTAAAACGCCAGGAAATTATGAAAGTAAACGTCAAAGAAAACCAACTAAGAAACTTCTTGAATCCAA TGATTTAGACCCTGGATTTATGCCCAAGAAGGGGGACCTTGGCCTTTCTAAAAAGTGCTATGAAGCTGGTCACCTGGAGAATGGCATAAC TGAATCTTGTGCCACATCTTATTCAAAAGATTTTGGTGGAGGCACTACCAAGATATTTGACAAGCCAAGGAAGCGAAAACGACAGAGGCA TGCTGCAGCCAAGATGCAGTGTAAAAAAGTGAAAAATGATGACTCGTCAAAAGAGATTCCAGGCTCAGAGGGAGAACTAATGCCTCACAG GACGGCCACAAGCCCCAAGGAGACTGTTGAGGAAGGTGTAGAACACGATCCCGGGATGCCTGCCTCTAAAAAAATGCAGGGTGAACGCGG TGGAGGAGCTGCACTCAAGGAGAATGTCTGTCAGCTGGCCAGTGGAGTGCCCCAGCTGGAATACCACTGTCTGGGTGGTTTCTATGGAAA CCTTTCCTCCCAGCGCCATGTGAATGACCACGAGTGGCACTCCATCCTGGTGGAGGAGATGGACGCTTCCATTCGCCTGATGGTTGACAG CATGGGCAACACCTCCCTTGTGGTCCCAGAGAACTGCCGTGGTCTGAGGCCCGAAAGGCACCTCTTGCTGGGCGGCCTCATTCTGTTGCA TTCTTCCTCGAATGTCTCCCAGGGCTTTGAAGGCTGCCTGGATGCTGTCGTGGTCAACGAAGAGGCTCTAGATCTGCTGGCCCCTGGCAA GACGGTGGCAGGCTTGCTGGAGACACAAGCCCTCACCCAGTGCTGCCTCCACAGTGACTACTGCAGCCAGAACACATGCCTCAATGGTGG GAAGTGCTCATGGACCCATGGGGCAGGCTATGTCTGCAAATGTCCCCCACAGTTCTCTGGGAAGCACTGTGAACAAGGAAGGGAGAACTG TACTTTTGCACCCTGCCTGGAAGGTGGAACTTGCATCCTCTCCCCCAAAGGAGCTTCCTGTAACTGCCCTCATCCTTACACAGGAGACAG GTGTGAAATGGAGGCGAGGGGTTGTTCAGAAGGACACTGCCTAGTCACTCCCGAGATCCAAAGGGGGGACTGGGGGCAGCAGGAGTTACT GATCATCACAGTGGCCGTGGCGTTCATTATCATAAGCACTGTCGGGCTTCTCTTCTACTGCCGCCGTTGCAAGTCTCACAAGCCTGTGGC CATGGAGGACCCAGACCTCCTGGCCAGGAGTGTTGGTGTTGACACCCAAGCCATGCCTGCCATCGAGCTCAACCCATTGAGTGCCAGCTC CTGCAACAACCTCAACCAACCGGAACCCAGCAAGGCCTCTGTTCCAAATGAACTCGTCACATTTGGACCCAATTCTAAGCAACGGCCAGT GGTCTGCAGTGTGCCCCCCAGACTCCCGCCAGCTGCGGTCCCTTCCCACTCTGACAATGAGCCTGTCATTAAGAGAACCTGGTCCAGCGA GGAGATGGTGTACCCTGGCGGAGCCATGGTCTGGCCCCCTACTTACTCCAGGAACGAACGCTGGGAATACCCCCACTCCGAAGTGACTCA GGGCCCTCTGCCGCCCTCGGCTCACCGCCACTCAACCCCAGTCGTGATGCCAGAGCCTAATGGCCTCTATGGGGGCTTCCCCTTCCCCCT GGAGATGGAAAACAAGCGGGCACCTCTCCCACCCCGTTACAGCAACCAGAACCTGGAAGATCTGATGCCCTCTCGGCCCCCTAGTCCCCG GGAGCGCCTGGTTGCCCCCTGTCTCAATGAGTACACGGCCATCAGCTACTACCACTCGCAGTTCCGGCAGGGAGGGGGAGGGCCCTGCCT GGCAGACGGGGGCTACAAGGGGGTGGGTATGCGCCTCAGCCGAGCTGGGCCCTCTTATGCTGTCTGTGAGGTGGAGGGGGCACCTCTTGC AGGCCAGGGCCAGCCCCGGGTGCCCCCCAACTATGAGGGCTCTGACATGGTGGAGAGTGATTATGGCAGCTGTGAGGAGGTCATGTTCTA GCTTCCCATTCCCAGAGCAAGGCAGGCGGGAGGCCAAGGACTGGACTTGGCTTATTTCTTCCTGTCTCGTAGGGGGTGAGTTGAGTGTGG CTGGGAGAGTGGGAGGGAAGCCCTCAGCCCAGGCTGTTGTCCCTTGAAATGTGCTCTTCCAATCCCCCACCTAGTCCCTGAGGGTGGAGG GAAGCTGAGGATAGAGCTCCAGAAACAGCACTAGGGTCCCAGGAGAGGGGCATTTCTAGAGCAGTGACCCTGGAAAACCAGGAACAATTG ACTCCCGGGGTGGGCGAGAGACAGGAGGGCTCCCTGATCTGCCGGCTCTCAGTCCCCGGGGCAGAGCCTGATTGACTGTGCTGGCTCAAC TTCACCAAGATGCATTCTCATACCTGCCCACAGCTCCATTTTGGAGGCAGGCAGGTTGGTGCCTGACAGACAACCACTACGCGGGCCGTA CAGAGGAGCTCTAGAGGGCTGCGTGGCATCCTCCTAGGGGCTGAGAGGTGAGCAGCAGGGGAGCGGGCACAGTCCCCTCTGCCCCTGCCT CAGTCGAGCACTCACTGTGTCTTTGTCAAGTGTCTGCTCCACGTCAGGCACTGTGCTTTGCACCGGGGAGAAAATGGTGATGGAGGGCAA CAAGGACTCCGAGGAGCACCACCAGGCCTCGGGCCCCAGAGGTCCCACTCCTCAGCCTACACGCAGAGGAACGGGCCCACCTCAGAGTCA CACCACTGGCTGCCAGTCAGGGCCTGCCAGGAGTCTACACAGCTCTGAACCTTCTTTGTTAAAGAATTCAGACCTCATGGAACTCTGGGT TCTTCATCCCAAGTTTCCCAGGCACTTTTGGCCAAAGGAAGGAAGGAACTAATTCTTCATTTTAAAAATTCTTAGGCACTTTTTGACCTT GCTGTCTGGATGAGTTTCCTCAATGGGATTTTTCTTCCCTAGACACAAGGAAGTCTGAACTCCTATTTAGGGCCGGTTGGAAGCAGGGAG CTGGACCGCAGTGTCCAGGCTGGACACCTGCCATTGCCTCCTCTCCATTGCAGACGCCTGCCCATCAAGTATTACCTGCGGCGACTCAAC CCTATGCATGGAGGGTCAATGTGGGCACATGTCTACACATGTGGGTGCCCATGGATAGTACGTGTGTACACATGTGTAGAGTGTATGTAG CCAGGAGTGGTGGGGACCAGAAGCCTCTGTGGCCTTTGGTGACCTCACCACTCCCTCCCACCCAGTCCCTCCCTCTGGTCCACTGCCTTT TCATATGTGTTGTTTCTGGAGACAGAAGTCAAAAGGAAGAGCAGTGGAGCCTTGCCCACAGGGCTGCTGCTTCATGCGAGAGGGAGATGT GTGGGCGAGAGCCAATTTGTGTGAGTGGTTTGTGGCTGTGTGTGTGACTGTGAGTGTGAGTGACAGATACATAGTTTCATTGGTCATTTT >60418_60418_2_NSD1-FAT2_NSD1_chr5_176675325_ENST00000354179_FAT2_chr5_150892167_ENST00000261800_length(amino acids)=1806AA_BP=1277 MPLKTRTALSDDPDSSTSTLGNMLELPGTSSSSTSQELPFCQPKKKSTPLKYEVGDLIWAKFKRRPWWPCRICSDPLINTHSKMKVSNRR PYRQYYVEAFGDPSERAWVAGKAIVMFEGRHQFEELPVLRRRGKQKEKGYRHKVPQKILSKWEASVGLAEQYDVPKGSKNRKCIPGSIKL DSEEDMPFEDCTNDPESEHDLLLNGCLKSLAFDSEHSADEKEKPCAKSRARKSSDNPKRTSVKKGHIQFEAHKDERRGKIPENLGLNFIS GDISDTQASNELSRIANSLTGSNTAPGSFLFSSCGKNTAKKEFETSNGDSLLGLPEGALISKCSREKNKPQRSLVCGSKVKLCYIGAGDE EKRSDSISICTTSDDGSSDLDPIEHSSESDNSVLEIPDAFDRTENMLSMQKNEKIKYSRFAATNTRVKAKQKPLISNSHTDHLMGCTKSA EPGTETSQVNLSDLKASTLVHKPQSDFTNDALSPKFNLSSSISSENSLIKGGAANQALLHSKSKQPKFRSIKCKHKENPVMAEPPVINEE CSLKCCSSDTKGSPLASISKSGKVDGLKLLNNMHEKTRDSSDIETAVVKHVLSELKELSYRSLGEDVSDSGTSKPSKPLLFSSASSQNHI PIEPDYKFSTLLMMLKDMHDSKTKEQRLMTAQNLVSYRSPGRGDCSTNSPVGVSKVLVSGGSTHNSEKKGDGTQNSANPSPSGGDSALSG ELSASLPGLLSDKRDLPASGKSRSDCVTRRNCGRSKPSSKLRDAFSAQMVKNTVNRKALKTERKRKLNQLPSVTLDAVLQGDRERGGSLR GGAEDPSKEDPLQIMGHLTSEDGDHFSDVHFDSKVKQSDPGKISEKGLSFENGKGPELDSVMNSENDELNGVNQVVPKKRWQRLNQRRTK PRKRMNRFKEKENSECAFRVLLPSDPVQEGRDEFPEHRTPSASILEEPLTEQNHADCLDSAGPRLNVCDKSSASIGDMEKEPGIPSLTPQ AELPEPAVRSEKKRLRKPSKWLLEYTEEYDQIFAPKKKQKKVQEQVHKVSSRCEEESLLARGRSSAQNKQVDENSLISTKEEPPVLEREA PFLEGPLAQSELGGGHAELPQLTLSVPVAPEVSPRPALESEELLVKTPGNYESKRQRKPTKKLLESNDLDPGFMPKKGDLGLSKKCYEAG HLENGITESCATSYSKDFGGGTTKIFDKPRKRKRQRHAAAKMQCKKVKNDDSSKEIPGSEGELMPHRTATSPKETVEEGVEHDPGMPASK KMQGERGGGAALKENVCQLASGVPQLEYHCLGGFYGNLSSQRHVNDHEWHSILVEEMDASIRLMVDSMGNTSLVVPENCRGLRPERHLLL GGLILLHSSSNVSQGFEGCLDAVVVNEEALDLLAPGKTVAGLLETQALTQCCLHSDYCSQNTCLNGGKCSWTHGAGYVCKCPPQFSGKHC EQGRENCTFAPCLEGGTCILSPKGASCNCPHPYTGDRCEMEARGCSEGHCLVTPEIQRGDWGQQELLIITVAVAFIIISTVGLLFYCRRC KSHKPVAMEDPDLLARSVGVDTQAMPAIELNPLSASSCNNLNQPEPSKASVPNELVTFGPNSKQRPVVCSVPPRLPPAAVPSHSDNEPVI KRTWSSEEMVYPGGAMVWPPTYSRNERWEYPHSEVTQGPLPPSAHRHSTPVVMPEPNGLYGGFPFPLEMENKRAPLPPRYSNQNLEDLMP SRPPSPRERLVAPCLNEYTAISYYHSQFRQGGGGPCLADGGYKGVGMRLSRAGPSYAVCEVEGAPLAGQGQPRVPPNYEGSDMVESDYGS -------------------------------------------------------------- >60418_60418_3_NSD1-FAT2_NSD1_chr5_176675325_ENST00000361032_FAT2_chr5_150892167_ENST00000261800_length(transcript)=7390nt_BP=4332nt ATGGATCAGACCTGTGAACTACCCAGAAGAAATTGTCTGCTGCCCTTTTCCAATCCAGTGAATTTAGATGCCCCTGAAGACAAGGACAGC CCTTTCGGTAATGGTCAATCCAATTTTTCTGAGCCACTTAATGGGTGTACTATGCAGTTATCGACTGTCAGTGGAACATCCCAAAATGCT TATGGACAAGATTCTCCATCTTGTTACATTCCACTGCGGAGACTACAGGATTTGGCCTCCATGATCAATGTAGAGTATTTAAATGGGTCT GCTGATGGATCAGAATCCTTTCAAGACCCTGAAAAAAGTGATTCAAGAGCTCAGACGCCAATTGTTTGCACTTCCTTGAGTCCTGGTGGT CCTACAGCACTTGCTATGAAACAGGAACCCTCTTGTAATAACTCCCCTGAACTCCAGGTAAAAGTAACAAAGACTATCAAGAATGGCTTT CTGCACTTTGAGAATTTTACTTGTGTGGACGATGCAGATGTAGATTCTGAAATGGACCCAGAACAGCCAGTCACAGAGGATGAGAGTATA GAGGAGATCTTTGAGGAAACTCAGACCAATGCCACCTGCAATTATGAGACTAAATCAGAGAATGGTGTAAAAGTGGCCATGGGAAGTGAA CAAGACAGCACACCAGAGAGTAGACACGGTGCAGTCAAATCGCCATTCTTGCCATTAGCTCCTCAGACTGAAACACAGAAAAATAAGCAA AGAAATGAAGTGGACGGCAGCAATGAAAAAGCAGCCCTTCTCCCAGCCCCCTTTTCACTAGGAGACACAAACATTACAATAGAAGAGCAA TTAAACTCAATAAATTTATCTTTTCAGGATGATCCAGATTCCAGTACCAGTACATTAGGAAACATGCTAGAATTACCTGGAACTTCATCA TCATCTACTTCACAGGAATTGCCATTTGTTCCTCAGAAAATTTTGAGTAAATGGGAAGCCAGTGTTGGACTTGCAGAACAGTATGATGTT CCCAAGGGGTCAAAGAACCGAAAATGTATTCCTGGTTCAATCAAGTTGGACAGTGAAGAAGATATGCCATTTGAAGACTGCACAAATGAT CCTGAGTCAGAACATGACCTGTTGCTTAATGGCTGTTTGAAATCACTGGCTTTTGATTCTGAACATTCTGCAGATGAGAAGGAAAAGCCT TGCGCTAAATCTCGAGCCAGAAAGAGCTCTGATAATCCAAAAAGGACTAGTGTGAAAAAGGGCCACATACAATTTGAAGCACATAAAGAT GAACGGAGGGGAAAGATTCCAGAGAACCTTGGCCTAAACTTTATCTCTGGGGATATATCTGATACGCAGGCCTCTAATGAACTTTCCAGG ATAGCAAATAGCCTCACAGGGTCCAACACTGCCCCAGGAAGTTTTCTGTTTTCTTCCTGTGGAAAAAACACTGCAAAGAAAGAATTTGAG ACTTCAAATGGTGACTCTTTATTGGGCTTGCCTGAGGGTGCTTTGATCTCAAAGTGTTCTCGAGAGAAGAATAAACCCCAACGAAGCCTG GTGTGTGGTTCAAAAGTGAAGCTCTGCTATATTGGAGCAGGTGATGAGGAAAAGCGAAGTGATTCCATTAGTATCTGTACCACTTCTGAT GATGGAAGCAGTGACCTGGATCCCATAGAACACAGCTCAGAGTCTGATAACAGTGTCCTTGAAATTCCAGATGCTTTCGATAGAACAGAG AACATGTTATCTATGCAGAAAAATGAAAAGATAAAGTATTCTAGGTTTGCTGCCACAAACACTAGGGTAAAAGCAAAACAGAAGCCTCTC ATTAGTAACTCACATACAGACCACTTAATGGGTTGTACTAAGAGTGCAGAGCCTGGAACCGAGACGTCTCAGGTTAATCTCTCTGATCTG AAGGCATCTACTCTTGTTCACAAACCCCAGTCAGATTTTACAAATGATGCTCTCTCTCCAAAATTCAACCTGTCATCAAGCATATCCAGT GAGAACTCGTTAATAAAGGGTGGGGCAGCAAATCAAGCTCTATTACATTCGAAAAGCAAACAGCCCAAGTTCCGAAGTATAAAGTGCAAA CACAAAGAAAATCCAGTTATGGCAGAACCCCCAGTTATAAATGAGGAGTGCAGTTTGAAATGCTGCTCTTCTGATACCAAAGGCTCTCCT TTGGCCAGCATTTCTAAAAGTGGGAAAGTGGATGGTCTAAAACTACTGAACAATATGCATGAGAAAACCAGGGATTCAAGTGACATAGAA ACAGCAGTGGTGAAACATGTTTTATCCGAGTTGAAGGAACTCTCTTACAGATCCTTAGGTGAGGATGTCAGTGACTCTGGAACATCAAAG CCATCAAAACCATTACTTTTCTCTTCTGCTTCTAGTCAGAATCACATACCTATTGAACCAGACTACAAATTCAGTACATTGCTAATGATG TTGAAAGATATGCATGATAGTAAGACGAAGGAGCAGCGGTTGATGACTGCTCAAAACCTGGTCTCTTACCGGAGTCCTGGTCGTGGGGAC TGTTCTACTAATAGTCCTGTAGGAGTCTCTAAGGTTTTGGTTTCAGGAGGCTCCACACACAATTCAGAGAAAAAGGGAGATGGCACTCAG AACTCCGCCAATCCTAGCCCTAGTGGGGGTGACTCTGCATTATCTGGCGAGTTGTCTGCTTCCCTACCTGGCTTACTGTCCGACAAGAGA GACCTCCCTGCTTCTGGTAAAAGTCGTTCAGACTGTGTTACTAGGCGCAACTGTGGACGATCAAAGCCTTCATCCAAATTGCGAGATGCT TTTTCAGCCCAAATGGTAAAGAACACAGTGAACCGTAAAGCCTTAAAGACCGAGCGCAAAAGAAAACTGAATCAGCTTCCAAGTGTGACT CTTGATGCTGTACTGCAGGGAGACCGAGAACGTGGAGGTTCATTGAGAGGTGGGGCAGAAGATCCTAGTAAAGAGGATCCCCTTCAGATA ATGGGCCACTTAACAAGTGAAGATGGTGACCATTTTTCTGATGTGCATTTCGATAGCAAGGTTAAGCAATCTGATCCTGGTAAAATTTCT GAAAAAGGACTCTCTTTTGAAAACGGAAAAGGCCCAGAGCTGGACTCTGTAATGAACAGTGAGAATGATGAACTCAATGGTGTAAATCAA GTGGTGCCTAAAAAGCGGTGGCAGCGTTTAAACCAAAGGCGCACTAAACCTCGTAAGCGCATGAACAGATTTAAAGAGAAAGAAAACTCT GAGTGTGCCTTTAGGGTCTTACTTCCTAGTGACCCTGTGCAGGAGGGGCGGGATGAGTTTCCAGAGCATAGAACTCCTTCAGCAAGCATA CTTGAGGAACCACTGACAGAGCAAAATCATGCTGACTGCTTAGATTCAGCTGGGCCACGGTTAAATGTTTGTGATAAATCCAGTGCCAGC ATTGGTGACATGGAAAAGGAGCCAGGAATTCCCAGTTTGACACCACAGGCTGAGCTCCCTGAACCAGCTGTGCGGTCAGAGAAGAAACGC CTTAGGAAGCCAAGCAAGTGGCTTTTGGAATATACAGAAGAATATGATCAGATATTTGCTCCTAAGAAAAAACAAAAGAAGGTACAGGAG CAGGTGCACAAGGTAAGTTCCCGCTGTGAAGAGGAAAGCCTTCTAGCCCGAGGTCGATCTAGTGCTCAGAACAAGCAGGTGGACGAGAAT TCTTTGATTTCAACCAAAGAAGAGCCTCCAGTTCTTGAAAGGGAGGCTCCGTTTTTGGAGGGCCCCTTGGCTCAGTCAGAACTTGGAGGT GGACATGCTGAGTTGCCGCAGCTGACCTTGTCTGTGCCTGTGGCTCCGGAAGTCTCTCCACGGCCTGCCCTTGAGTCTGAGGAATTGCTA GTTAAAACGCCAGGAAATTATGAAAGTAAACGTCAAAGAAAACCAACTAAGAAACTTCTTGAATCCAATGATTTAGACCCTGGATTTATG CCCAAGAAGGGGGACCTTGGCCTTTCTAAAAAGTGCTATGAAGCTGGTCACCTGGAGAATGGCATAACTGAATCTTGTGCCACATCTTAT TCAAAAGATTTTGGTGGAGGCACTACCAAGATATTTGACAAGCCAAGGAAGCGAAAACGACAGAGGCATGCTGCAGCCAAGATGCAGTGT AAAAAAGTGAAAAATGATGACTCGTCAAAAGAGATTCCAGGCTCAGAGGGAGAACTAATGCCTCACAGGACGGCCACAAGCCCCAAGGAG ACTGTTGAGGAAGGTGTAGAACACGATCCCGGGATGCCTGCCTCTAAAAAAATGCAGGGTGAACGCGGTGGAGGAGCTGCACTCAAGGAG AATGTCTGTCAGCTGGCCAGTGGAGTGCCCCAGCTGGAATACCACTGTCTGGGTGGTTTCTATGGAAACCTTTCCTCCCAGCGCCATGTG AATGACCACGAGTGGCACTCCATCCTGGTGGAGGAGATGGACGCTTCCATTCGCCTGATGGTTGACAGCATGGGCAACACCTCCCTTGTG GTCCCAGAGAACTGCCGTGGTCTGAGGCCCGAAAGGCACCTCTTGCTGGGCGGCCTCATTCTGTTGCATTCTTCCTCGAATGTCTCCCAG GGCTTTGAAGGCTGCCTGGATGCTGTCGTGGTCAACGAAGAGGCTCTAGATCTGCTGGCCCCTGGCAAGACGGTGGCAGGCTTGCTGGAG ACACAAGCCCTCACCCAGTGCTGCCTCCACAGTGACTACTGCAGCCAGAACACATGCCTCAATGGTGGGAAGTGCTCATGGACCCATGGG GCAGGCTATGTCTGCAAATGTCCCCCACAGTTCTCTGGGAAGCACTGTGAACAAGGAAGGGAGAACTGTACTTTTGCACCCTGCCTGGAA GGTGGAACTTGCATCCTCTCCCCCAAAGGAGCTTCCTGTAACTGCCCTCATCCTTACACAGGAGACAGGTGTGAAATGGAGGCGAGGGGT TGTTCAGAAGGACACTGCCTAGTCACTCCCGAGATCCAAAGGGGGGACTGGGGGCAGCAGGAGTTACTGATCATCACAGTGGCCGTGGCG TTCATTATCATAAGCACTGTCGGGCTTCTCTTCTACTGCCGCCGTTGCAAGTCTCACAAGCCTGTGGCCATGGAGGACCCAGACCTCCTG GCCAGGAGTGTTGGTGTTGACACCCAAGCCATGCCTGCCATCGAGCTCAACCCATTGAGTGCCAGCTCCTGCAACAACCTCAACCAACCG GAACCCAGCAAGGCCTCTGTTCCAAATGAACTCGTCACATTTGGACCCAATTCTAAGCAACGGCCAGTGGTCTGCAGTGTGCCCCCCAGA CTCCCGCCAGCTGCGGTCCCTTCCCACTCTGACAATGAGCCTGTCATTAAGAGAACCTGGTCCAGCGAGGAGATGGTGTACCCTGGCGGA GCCATGGTCTGGCCCCCTACTTACTCCAGGAACGAACGCTGGGAATACCCCCACTCCGAAGTGACTCAGGGCCCTCTGCCGCCCTCGGCT CACCGCCACTCAACCCCAGTCGTGATGCCAGAGCCTAATGGCCTCTATGGGGGCTTCCCCTTCCCCCTGGAGATGGAAAACAAGCGGGCA CCTCTCCCACCCCGTTACAGCAACCAGAACCTGGAAGATCTGATGCCCTCTCGGCCCCCTAGTCCCCGGGAGCGCCTGGTTGCCCCCTGT CTCAATGAGTACACGGCCATCAGCTACTACCACTCGCAGTTCCGGCAGGGAGGGGGAGGGCCCTGCCTGGCAGACGGGGGCTACAAGGGG GTGGGTATGCGCCTCAGCCGAGCTGGGCCCTCTTATGCTGTCTGTGAGGTGGAGGGGGCACCTCTTGCAGGCCAGGGCCAGCCCCGGGTG CCCCCCAACTATGAGGGCTCTGACATGGTGGAGAGTGATTATGGCAGCTGTGAGGAGGTCATGTTCTAGCTTCCCATTCCCAGAGCAAGG CAGGCGGGAGGCCAAGGACTGGACTTGGCTTATTTCTTCCTGTCTCGTAGGGGGTGAGTTGAGTGTGGCTGGGAGAGTGGGAGGGAAGCC CTCAGCCCAGGCTGTTGTCCCTTGAAATGTGCTCTTCCAATCCCCCACCTAGTCCCTGAGGGTGGAGGGAAGCTGAGGATAGAGCTCCAG AAACAGCACTAGGGTCCCAGGAGAGGGGCATTTCTAGAGCAGTGACCCTGGAAAACCAGGAACAATTGACTCCCGGGGTGGGCGAGAGAC AGGAGGGCTCCCTGATCTGCCGGCTCTCAGTCCCCGGGGCAGAGCCTGATTGACTGTGCTGGCTCAACTTCACCAAGATGCATTCTCATA CCTGCCCACAGCTCCATTTTGGAGGCAGGCAGGTTGGTGCCTGACAGACAACCACTACGCGGGCCGTACAGAGGAGCTCTAGAGGGCTGC GTGGCATCCTCCTAGGGGCTGAGAGGTGAGCAGCAGGGGAGCGGGCACAGTCCCCTCTGCCCCTGCCTCAGTCGAGCACTCACTGTGTCT TTGTCAAGTGTCTGCTCCACGTCAGGCACTGTGCTTTGCACCGGGGAGAAAATGGTGATGGAGGGCAACAAGGACTCCGAGGAGCACCAC CAGGCCTCGGGCCCCAGAGGTCCCACTCCTCAGCCTACACGCAGAGGAACGGGCCCACCTCAGAGTCACACCACTGGCTGCCAGTCAGGG CCTGCCAGGAGTCTACACAGCTCTGAACCTTCTTTGTTAAAGAATTCAGACCTCATGGAACTCTGGGTTCTTCATCCCAAGTTTCCCAGG CACTTTTGGCCAAAGGAAGGAAGGAACTAATTCTTCATTTTAAAAATTCTTAGGCACTTTTTGACCTTGCTGTCTGGATGAGTTTCCTCA ATGGGATTTTTCTTCCCTAGACACAAGGAAGTCTGAACTCCTATTTAGGGCCGGTTGGAAGCAGGGAGCTGGACCGCAGTGTCCAGGCTG GACACCTGCCATTGCCTCCTCTCCATTGCAGACGCCTGCCCATCAAGTATTACCTGCGGCGACTCAACCCTATGCATGGAGGGTCAATGT GGGCACATGTCTACACATGTGGGTGCCCATGGATAGTACGTGTGTACACATGTGTAGAGTGTATGTAGCCAGGAGTGGTGGGGACCAGAA GCCTCTGTGGCCTTTGGTGACCTCACCACTCCCTCCCACCCAGTCCCTCCCTCTGGTCCACTGCCTTTTCATATGTGTTGTTTCTGGAGA CAGAAGTCAAAAGGAAGAGCAGTGGAGCCTTGCCCACAGGGCTGCTGCTTCATGCGAGAGGGAGATGTGTGGGCGAGAGCCAATTTGTGT GAGTGGTTTGTGGCTGTGTGTGTGACTGTGAGTGTGAGTGACAGATACATAGTTTCATTGGTCATTTTTTTTTTAACAATAAAGTATCTT >60418_60418_3_NSD1-FAT2_NSD1_chr5_176675325_ENST00000361032_FAT2_chr5_150892167_ENST00000261800_length(amino acids)=1972AA_BP=1443 MDQTCELPRRNCLLPFSNPVNLDAPEDKDSPFGNGQSNFSEPLNGCTMQLSTVSGTSQNAYGQDSPSCYIPLRRLQDLASMINVEYLNGS ADGSESFQDPEKSDSRAQTPIVCTSLSPGGPTALAMKQEPSCNNSPELQVKVTKTIKNGFLHFENFTCVDDADVDSEMDPEQPVTEDESI EEIFEETQTNATCNYETKSENGVKVAMGSEQDSTPESRHGAVKSPFLPLAPQTETQKNKQRNEVDGSNEKAALLPAPFSLGDTNITIEEQ LNSINLSFQDDPDSSTSTLGNMLELPGTSSSSTSQELPFVPQKILSKWEASVGLAEQYDVPKGSKNRKCIPGSIKLDSEEDMPFEDCTND PESEHDLLLNGCLKSLAFDSEHSADEKEKPCAKSRARKSSDNPKRTSVKKGHIQFEAHKDERRGKIPENLGLNFISGDISDTQASNELSR IANSLTGSNTAPGSFLFSSCGKNTAKKEFETSNGDSLLGLPEGALISKCSREKNKPQRSLVCGSKVKLCYIGAGDEEKRSDSISICTTSD DGSSDLDPIEHSSESDNSVLEIPDAFDRTENMLSMQKNEKIKYSRFAATNTRVKAKQKPLISNSHTDHLMGCTKSAEPGTETSQVNLSDL KASTLVHKPQSDFTNDALSPKFNLSSSISSENSLIKGGAANQALLHSKSKQPKFRSIKCKHKENPVMAEPPVINEECSLKCCSSDTKGSP LASISKSGKVDGLKLLNNMHEKTRDSSDIETAVVKHVLSELKELSYRSLGEDVSDSGTSKPSKPLLFSSASSQNHIPIEPDYKFSTLLMM LKDMHDSKTKEQRLMTAQNLVSYRSPGRGDCSTNSPVGVSKVLVSGGSTHNSEKKGDGTQNSANPSPSGGDSALSGELSASLPGLLSDKR DLPASGKSRSDCVTRRNCGRSKPSSKLRDAFSAQMVKNTVNRKALKTERKRKLNQLPSVTLDAVLQGDRERGGSLRGGAEDPSKEDPLQI MGHLTSEDGDHFSDVHFDSKVKQSDPGKISEKGLSFENGKGPELDSVMNSENDELNGVNQVVPKKRWQRLNQRRTKPRKRMNRFKEKENS ECAFRVLLPSDPVQEGRDEFPEHRTPSASILEEPLTEQNHADCLDSAGPRLNVCDKSSASIGDMEKEPGIPSLTPQAELPEPAVRSEKKR LRKPSKWLLEYTEEYDQIFAPKKKQKKVQEQVHKVSSRCEEESLLARGRSSAQNKQVDENSLISTKEEPPVLEREAPFLEGPLAQSELGG GHAELPQLTLSVPVAPEVSPRPALESEELLVKTPGNYESKRQRKPTKKLLESNDLDPGFMPKKGDLGLSKKCYEAGHLENGITESCATSY SKDFGGGTTKIFDKPRKRKRQRHAAAKMQCKKVKNDDSSKEIPGSEGELMPHRTATSPKETVEEGVEHDPGMPASKKMQGERGGGAALKE NVCQLASGVPQLEYHCLGGFYGNLSSQRHVNDHEWHSILVEEMDASIRLMVDSMGNTSLVVPENCRGLRPERHLLLGGLILLHSSSNVSQ GFEGCLDAVVVNEEALDLLAPGKTVAGLLETQALTQCCLHSDYCSQNTCLNGGKCSWTHGAGYVCKCPPQFSGKHCEQGRENCTFAPCLE GGTCILSPKGASCNCPHPYTGDRCEMEARGCSEGHCLVTPEIQRGDWGQQELLIITVAVAFIIISTVGLLFYCRRCKSHKPVAMEDPDLL ARSVGVDTQAMPAIELNPLSASSCNNLNQPEPSKASVPNELVTFGPNSKQRPVVCSVPPRLPPAAVPSHSDNEPVIKRTWSSEEMVYPGG AMVWPPTYSRNERWEYPHSEVTQGPLPPSAHRHSTPVVMPEPNGLYGGFPFPLEMENKRAPLPPRYSNQNLEDLMPSRPPSPRERLVAPC -------------------------------------------------------------- >60418_60418_4_NSD1-FAT2_NSD1_chr5_176675325_ENST00000439151_FAT2_chr5_150892167_ENST00000261800_length(transcript)=7744nt_BP=4686nt GCTGGCCCGGGAGGGGGCGCGGGGCACGGTTGATGCCGGCCCAGGATGGATCAGACCTGTGAACTACCCAGAAGAAATTGTCTGCTGCCC TTTTCCAATCCAGTGAATTTAGATGCCCCTGAAGACAAGGACAGCCCTTTCGGTAATGGTCAATCCAATTTTTCTGAGCCACTTAATGGG TGTACTATGCAGTTATCGACTGTCAGTGGAACATCCCAAAATGCTTATGGACAAGATTCTCCATCTTGTTACATTCCACTGCGGAGACTA CAGGATTTGGCCTCCATGATCAATGTAGAGTATTTAAATGGGTCTGCTGATGGATCAGAATCCTTTCAAGACCCTGAAAAAAGTGATTCA AGAGCTCAGACGCCAATTGTTTGCACTTCCTTGAGTCCTGGTGGTCCTACAGCACTTGCTATGAAACAGGAACCCTCTTGTAATAACTCC CCTGAACTCCAGGTAAAAGTAACAAAGACTATCAAGAATGGCTTTCTGCACTTTGAGAATTTTACTTGTGTGGACGATGCAGATGTAGAT TCTGAAATGGACCCAGAACAGCCAGTCACAGAGGATGAGAGTATAGAGGAGATCTTTGAGGAAACTCAGACCAATGCCACCTGCAATTAT GAGACTAAATCAGAGAATGGTGTAAAAGTGGCCATGGGAAGTGAACAAGACAGCACACCAGAGAGTAGACACGGTGCAGTCAAATCGCCA TTCTTGCCATTAGCTCCTCAGACTGAAACACAGAAAAATAAGCAAAGAAATGAAGTGGACGGCAGCAATGAAAAAGCAGCCCTTCTCCCA GCCCCCTTTTCACTAGGAGACACAAACATTACAATAGAAGAGCAATTAAACTCAATAAATTTATCTTTTCAGGATGATCCAGATTCCAGT ACCAGTACATTAGGAAACATGCTAGAATTACCTGGAACTTCATCATCATCTACTTCACAGGAATTGCCATTTTGTCAACCTAAGAAAAAG TCTACGCCACTGAAGTATGAAGTTGGAGATCTCATCTGGGCAAAATTCAAGAGACGCCCATGGTGGCCCTGCAGGATTTGTTCTGATCCG TTGATTAACACACATTCAAAAATGAAAGTTTCCAACCGGAGGCCCTATCGGCAGTACTACGTGGAGGCTTTTGGAGATCCTTCTGAGAGA GCCTGGGTGGCTGGAAAAGCAATCGTCATGTTTGAAGGCAGACATCAATTCGAAGAGCTACCTGTCCTTAGGAGAAGAGGGAAACAGAAA GAAAAAGGATATAGGCATAAGGTTCCTCAGAAAATTTTGAGTAAATGGGAAGCCAGTGTTGGACTTGCAGAACAGTATGATGTTCCCAAG GGGTCAAAGAACCGAAAATGTATTCCTGGTTCAATCAAGTTGGACAGTGAAGAAGATATGCCATTTGAAGACTGCACAAATGATCCTGAG TCAGAACATGACCTGTTGCTTAATGGCTGTTTGAAATCACTGGCTTTTGATTCTGAACATTCTGCAGATGAGAAGGAAAAGCCTTGCGCT AAATCTCGAGCCAGAAAGAGCTCTGATAATCCAAAAAGGACTAGTGTGAAAAAGGGCCACATACAATTTGAAGCACATAAAGATGAACGG AGGGGAAAGATTCCAGAGAACCTTGGCCTAAACTTTATCTCTGGGGATATATCTGATACGCAGGCCTCTAATGAACTTTCCAGGATAGCA AATAGCCTCACAGGGTCCAACACTGCCCCAGGAAGTTTTCTGTTTTCTTCCTGTGGAAAAAACACTGCAAAGAAAGAATTTGAGACTTCA AATGGTGACTCTTTATTGGGCTTGCCTGAGGGTGCTTTGATCTCAAAGTGTTCTCGAGAGAAGAATAAACCCCAACGAAGCCTGGTGTGT GGTTCAAAAGTGAAGCTCTGCTATATTGGAGCAGGTGATGAGGAAAAGCGAAGTGATTCCATTAGTATCTGTACCACTTCTGATGATGGA AGCAGTGACCTGGATCCCATAGAACACAGCTCAGAGTCTGATAACAGTGTCCTTGAAATTCCAGATGCTTTCGATAGAACAGAGAACATG TTATCTATGCAGAAAAATGAAAAGATAAAGTATTCTAGGTTTGCTGCCACAAACACTAGGGTAAAAGCAAAACAGAAGCCTCTCATTAGT AACTCACATACAGACCACTTAATGGGTTGTACTAAGAGTGCAGAGCCTGGAACCGAGACGTCTCAGGTTAATCTCTCTGATCTGAAGGCA TCTACTCTTGTTCACAAACCCCAGTCAGATTTTACAAATGATGCTCTCTCTCCAAAATTCAACCTGTCATCAAGCATATCCAGTGAGAAC TCGTTAATAAAGGGTGGGGCAGCAAATCAAGCTCTATTACATTCGAAAAGCAAACAGCCCAAGTTCCGAAGTATAAAGTGCAAACACAAA GAAAATCCAGTTATGGCAGAACCCCCAGTTATAAATGAGGAGTGCAGTTTGAAATGCTGCTCTTCTGATACCAAAGGCTCTCCTTTGGCC AGCATTTCTAAAAGTGGGAAAGTGGATGGTCTAAAACTACTGAACAATATGCATGAGAAAACCAGGGATTCAAGTGACATAGAAACAGCA GTGGTGAAACATGTTTTATCCGAGTTGAAGGAACTCTCTTACAGATCCTTAGGTGAGGATGTCAGTGACTCTGGAACATCAAAGCCATCA AAACCATTACTTTTCTCTTCTGCTTCTAGTCAGAATCACATACCTATTGAACCAGACTACAAATTCAGTACATTGCTAATGATGTTGAAA GATATGCATGATAGTAAGACGAAGGAGCAGCGGTTGATGACTGCTCAAAACCTGGTCTCTTACCGGAGTCCTGGTCGTGGGGACTGTTCT ACTAATAGTCCTGTAGGAGTCTCTAAGGTTTTGGTTTCAGGAGGCTCCACACACAATTCAGAGAAAAAGGGAGATGGCACTCAGAACTCC GCCAATCCTAGCCCTAGTGGGGGTGACTCTGCATTATCTGGCGAGTTGTCTGCTTCCCTACCTGGCTTACTGTCCGACAAGAGAGACCTC CCTGCTTCTGGTAAAAGTCGTTCAGACTGTGTTACTAGGCGCAACTGTGGACGATCAAAGCCTTCATCCAAATTGCGAGATGCTTTTTCA GCCCAAATGGTAAAGAACACAGTGAACCGTAAAGCCTTAAAGACCGAGCGCAAAAGAAAACTGAATCAGCTTCCAAGTGTGACTCTTGAT GCTGTACTGCAGGGAGACCGAGAACGTGGAGGTTCATTGAGAGGTGGGGCAGAAGATCCTAGTAAAGAGGATCCCCTTCAGATAATGGGC CACTTAACAAGTGAAGATGGTGACCATTTTTCTGATGTGCATTTCGATAGCAAGGTTAAGCAATCTGATCCTGGTAAAATTTCTGAAAAA GGACTCTCTTTTGAAAACGGAAAAGGCCCAGAGCTGGACTCTGTAATGAACAGTGAGAATGATGAACTCAATGGTGTAAATCAAGTGGTG CCTAAAAAGCGGTGGCAGCGTTTAAACCAAAGGCGCACTAAACCTCGTAAGCGCATGAACAGATTTAAAGAGAAAGAAAACTCTGAGTGT GCCTTTAGGGTCTTACTTCCTAGTGACCCTGTGCAGGAGGGGCGGGATGAGTTTCCAGAGCATAGAACTCCTTCAGCAAGCATACTTGAG GAACCACTGACAGAGCAAAATCATGCTGACTGCTTAGATTCAGCTGGGCCACGGTTAAATGTTTGTGATAAATCCAGTGCCAGCATTGGT GACATGGAAAAGGAGCCAGGAATTCCCAGTTTGACACCACAGGCTGAGCTCCCTGAACCAGCTGTGCGGTCAGAGAAGAAACGCCTTAGG AAGCCAAGCAAGTGGCTTTTGGAATATACAGAAGAATATGATCAGATATTTGCTCCTAAGAAAAAACAAAAGAAGGTACAGGAGCAGGTG CACAAGGTAAGTTCCCGCTGTGAAGAGGAAAGCCTTCTAGCCCGAGGTCGATCTAGTGCTCAGAACAAGCAGGTGGACGAGAATTCTTTG ATTTCAACCAAAGAAGAGCCTCCAGTTCTTGAAAGGGAGGCTCCGTTTTTGGAGGGCCCCTTGGCTCAGTCAGAACTTGGAGGTGGACAT GCTGAGTTGCCGCAGCTGACCTTGTCTGTGCCTGTGGCTCCGGAAGTCTCTCCACGGCCTGCCCTTGAGTCTGAGGAATTGCTAGTTAAA ACGCCAGGAAATTATGAAAGTAAACGTCAAAGAAAACCAACTAAGAAACTTCTTGAATCCAATGATTTAGACCCTGGATTTATGCCCAAG AAGGGGGACCTTGGCCTTTCTAAAAAGTGCTATGAAGCTGGTCACCTGGAGAATGGCATAACTGAATCTTGTGCCACATCTTATTCAAAA GATTTTGGTGGAGGCACTACCAAGATATTTGACAAGCCAAGGAAGCGAAAACGACAGAGGCATGCTGCAGCCAAGATGCAGTGTAAAAAA GTGAAAAATGATGACTCGTCAAAAGAGATTCCAGGCTCAGAGGGAGAACTAATGCCTCACAGGACGGCCACAAGCCCCAAGGAGACTGTT GAGGAAGGTGTAGAACACGATCCCGGGATGCCTGCCTCTAAAAAAATGCAGGGTGAACGCGGTGGAGGAGCTGCACTCAAGGAGAATGTC TGTCAGCTGGCCAGTGGAGTGCCCCAGCTGGAATACCACTGTCTGGGTGGTTTCTATGGAAACCTTTCCTCCCAGCGCCATGTGAATGAC CACGAGTGGCACTCCATCCTGGTGGAGGAGATGGACGCTTCCATTCGCCTGATGGTTGACAGCATGGGCAACACCTCCCTTGTGGTCCCA GAGAACTGCCGTGGTCTGAGGCCCGAAAGGCACCTCTTGCTGGGCGGCCTCATTCTGTTGCATTCTTCCTCGAATGTCTCCCAGGGCTTT GAAGGCTGCCTGGATGCTGTCGTGGTCAACGAAGAGGCTCTAGATCTGCTGGCCCCTGGCAAGACGGTGGCAGGCTTGCTGGAGACACAA GCCCTCACCCAGTGCTGCCTCCACAGTGACTACTGCAGCCAGAACACATGCCTCAATGGTGGGAAGTGCTCATGGACCCATGGGGCAGGC TATGTCTGCAAATGTCCCCCACAGTTCTCTGGGAAGCACTGTGAACAAGGAAGGGAGAACTGTACTTTTGCACCCTGCCTGGAAGGTGGA ACTTGCATCCTCTCCCCCAAAGGAGCTTCCTGTAACTGCCCTCATCCTTACACAGGAGACAGGTGTGAAATGGAGGCGAGGGGTTGTTCA GAAGGACACTGCCTAGTCACTCCCGAGATCCAAAGGGGGGACTGGGGGCAGCAGGAGTTACTGATCATCACAGTGGCCGTGGCGTTCATT ATCATAAGCACTGTCGGGCTTCTCTTCTACTGCCGCCGTTGCAAGTCTCACAAGCCTGTGGCCATGGAGGACCCAGACCTCCTGGCCAGG AGTGTTGGTGTTGACACCCAAGCCATGCCTGCCATCGAGCTCAACCCATTGAGTGCCAGCTCCTGCAACAACCTCAACCAACCGGAACCC AGCAAGGCCTCTGTTCCAAATGAACTCGTCACATTTGGACCCAATTCTAAGCAACGGCCAGTGGTCTGCAGTGTGCCCCCCAGACTCCCG CCAGCTGCGGTCCCTTCCCACTCTGACAATGAGCCTGTCATTAAGAGAACCTGGTCCAGCGAGGAGATGGTGTACCCTGGCGGAGCCATG GTCTGGCCCCCTACTTACTCCAGGAACGAACGCTGGGAATACCCCCACTCCGAAGTGACTCAGGGCCCTCTGCCGCCCTCGGCTCACCGC CACTCAACCCCAGTCGTGATGCCAGAGCCTAATGGCCTCTATGGGGGCTTCCCCTTCCCCCTGGAGATGGAAAACAAGCGGGCACCTCTC CCACCCCGTTACAGCAACCAGAACCTGGAAGATCTGATGCCCTCTCGGCCCCCTAGTCCCCGGGAGCGCCTGGTTGCCCCCTGTCTCAAT GAGTACACGGCCATCAGCTACTACCACTCGCAGTTCCGGCAGGGAGGGGGAGGGCCCTGCCTGGCAGACGGGGGCTACAAGGGGGTGGGT ATGCGCCTCAGCCGAGCTGGGCCCTCTTATGCTGTCTGTGAGGTGGAGGGGGCACCTCTTGCAGGCCAGGGCCAGCCCCGGGTGCCCCCC AACTATGAGGGCTCTGACATGGTGGAGAGTGATTATGGCAGCTGTGAGGAGGTCATGTTCTAGCTTCCCATTCCCAGAGCAAGGCAGGCG GGAGGCCAAGGACTGGACTTGGCTTATTTCTTCCTGTCTCGTAGGGGGTGAGTTGAGTGTGGCTGGGAGAGTGGGAGGGAAGCCCTCAGC CCAGGCTGTTGTCCCTTGAAATGTGCTCTTCCAATCCCCCACCTAGTCCCTGAGGGTGGAGGGAAGCTGAGGATAGAGCTCCAGAAACAG CACTAGGGTCCCAGGAGAGGGGCATTTCTAGAGCAGTGACCCTGGAAAACCAGGAACAATTGACTCCCGGGGTGGGCGAGAGACAGGAGG GCTCCCTGATCTGCCGGCTCTCAGTCCCCGGGGCAGAGCCTGATTGACTGTGCTGGCTCAACTTCACCAAGATGCATTCTCATACCTGCC CACAGCTCCATTTTGGAGGCAGGCAGGTTGGTGCCTGACAGACAACCACTACGCGGGCCGTACAGAGGAGCTCTAGAGGGCTGCGTGGCA TCCTCCTAGGGGCTGAGAGGTGAGCAGCAGGGGAGCGGGCACAGTCCCCTCTGCCCCTGCCTCAGTCGAGCACTCACTGTGTCTTTGTCA AGTGTCTGCTCCACGTCAGGCACTGTGCTTTGCACCGGGGAGAAAATGGTGATGGAGGGCAACAAGGACTCCGAGGAGCACCACCAGGCC TCGGGCCCCAGAGGTCCCACTCCTCAGCCTACACGCAGAGGAACGGGCCCACCTCAGAGTCACACCACTGGCTGCCAGTCAGGGCCTGCC AGGAGTCTACACAGCTCTGAACCTTCTTTGTTAAAGAATTCAGACCTCATGGAACTCTGGGTTCTTCATCCCAAGTTTCCCAGGCACTTT TGGCCAAAGGAAGGAAGGAACTAATTCTTCATTTTAAAAATTCTTAGGCACTTTTTGACCTTGCTGTCTGGATGAGTTTCCTCAATGGGA TTTTTCTTCCCTAGACACAAGGAAGTCTGAACTCCTATTTAGGGCCGGTTGGAAGCAGGGAGCTGGACCGCAGTGTCCAGGCTGGACACC TGCCATTGCCTCCTCTCCATTGCAGACGCCTGCCCATCAAGTATTACCTGCGGCGACTCAACCCTATGCATGGAGGGTCAATGTGGGCAC ATGTCTACACATGTGGGTGCCCATGGATAGTACGTGTGTACACATGTGTAGAGTGTATGTAGCCAGGAGTGGTGGGGACCAGAAGCCTCT GTGGCCTTTGGTGACCTCACCACTCCCTCCCACCCAGTCCCTCCCTCTGGTCCACTGCCTTTTCATATGTGTTGTTTCTGGAGACAGAAG TCAAAAGGAAGAGCAGTGGAGCCTTGCCCACAGGGCTGCTGCTTCATGCGAGAGGGAGATGTGTGGGCGAGAGCCAATTTGTGTGAGTGG TTTGTGGCTGTGTGTGTGACTGTGAGTGTGAGTGACAGATACATAGTTTCATTGGTCATTTTTTTTTTAACAATAAAGTATCTTTTTTTA >60418_60418_4_NSD1-FAT2_NSD1_chr5_176675325_ENST00000439151_FAT2_chr5_150892167_ENST00000261800_length(amino acids)=2075AA_BP=1546 MDQTCELPRRNCLLPFSNPVNLDAPEDKDSPFGNGQSNFSEPLNGCTMQLSTVSGTSQNAYGQDSPSCYIPLRRLQDLASMINVEYLNGS ADGSESFQDPEKSDSRAQTPIVCTSLSPGGPTALAMKQEPSCNNSPELQVKVTKTIKNGFLHFENFTCVDDADVDSEMDPEQPVTEDESI EEIFEETQTNATCNYETKSENGVKVAMGSEQDSTPESRHGAVKSPFLPLAPQTETQKNKQRNEVDGSNEKAALLPAPFSLGDTNITIEEQ LNSINLSFQDDPDSSTSTLGNMLELPGTSSSSTSQELPFCQPKKKSTPLKYEVGDLIWAKFKRRPWWPCRICSDPLINTHSKMKVSNRRP YRQYYVEAFGDPSERAWVAGKAIVMFEGRHQFEELPVLRRRGKQKEKGYRHKVPQKILSKWEASVGLAEQYDVPKGSKNRKCIPGSIKLD SEEDMPFEDCTNDPESEHDLLLNGCLKSLAFDSEHSADEKEKPCAKSRARKSSDNPKRTSVKKGHIQFEAHKDERRGKIPENLGLNFISG DISDTQASNELSRIANSLTGSNTAPGSFLFSSCGKNTAKKEFETSNGDSLLGLPEGALISKCSREKNKPQRSLVCGSKVKLCYIGAGDEE KRSDSISICTTSDDGSSDLDPIEHSSESDNSVLEIPDAFDRTENMLSMQKNEKIKYSRFAATNTRVKAKQKPLISNSHTDHLMGCTKSAE PGTETSQVNLSDLKASTLVHKPQSDFTNDALSPKFNLSSSISSENSLIKGGAANQALLHSKSKQPKFRSIKCKHKENPVMAEPPVINEEC SLKCCSSDTKGSPLASISKSGKVDGLKLLNNMHEKTRDSSDIETAVVKHVLSELKELSYRSLGEDVSDSGTSKPSKPLLFSSASSQNHIP IEPDYKFSTLLMMLKDMHDSKTKEQRLMTAQNLVSYRSPGRGDCSTNSPVGVSKVLVSGGSTHNSEKKGDGTQNSANPSPSGGDSALSGE LSASLPGLLSDKRDLPASGKSRSDCVTRRNCGRSKPSSKLRDAFSAQMVKNTVNRKALKTERKRKLNQLPSVTLDAVLQGDRERGGSLRG GAEDPSKEDPLQIMGHLTSEDGDHFSDVHFDSKVKQSDPGKISEKGLSFENGKGPELDSVMNSENDELNGVNQVVPKKRWQRLNQRRTKP RKRMNRFKEKENSECAFRVLLPSDPVQEGRDEFPEHRTPSASILEEPLTEQNHADCLDSAGPRLNVCDKSSASIGDMEKEPGIPSLTPQA ELPEPAVRSEKKRLRKPSKWLLEYTEEYDQIFAPKKKQKKVQEQVHKVSSRCEEESLLARGRSSAQNKQVDENSLISTKEEPPVLEREAP FLEGPLAQSELGGGHAELPQLTLSVPVAPEVSPRPALESEELLVKTPGNYESKRQRKPTKKLLESNDLDPGFMPKKGDLGLSKKCYEAGH LENGITESCATSYSKDFGGGTTKIFDKPRKRKRQRHAAAKMQCKKVKNDDSSKEIPGSEGELMPHRTATSPKETVEEGVEHDPGMPASKK MQGERGGGAALKENVCQLASGVPQLEYHCLGGFYGNLSSQRHVNDHEWHSILVEEMDASIRLMVDSMGNTSLVVPENCRGLRPERHLLLG GLILLHSSSNVSQGFEGCLDAVVVNEEALDLLAPGKTVAGLLETQALTQCCLHSDYCSQNTCLNGGKCSWTHGAGYVCKCPPQFSGKHCE QGRENCTFAPCLEGGTCILSPKGASCNCPHPYTGDRCEMEARGCSEGHCLVTPEIQRGDWGQQELLIITVAVAFIIISTVGLLFYCRRCK SHKPVAMEDPDLLARSVGVDTQAMPAIELNPLSASSCNNLNQPEPSKASVPNELVTFGPNSKQRPVVCSVPPRLPPAAVPSHSDNEPVIK RTWSSEEMVYPGGAMVWPPTYSRNERWEYPHSEVTQGPLPPSAHRHSTPVVMPEPNGLYGGFPFPLEMENKRAPLPPRYSNQNLEDLMPS RPPSPRERLVAPCLNEYTAISYYHSQFRQGGGGPCLADGGYKGVGMRLSRAGPSYAVCEVEGAPLAGQGQPRVPPNYEGSDMVESDYGSC -------------------------------------------------------------- |
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Fusion Gene PPI Analysis for NSD1-FAT2 |
| Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in |
| Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160) |
| Hgene | Hgene's interactors | Tgene | Tgene's interactors |
| - Retained PPIs in in-frame fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Still interaction with |
| - Lost PPIs in in-frame fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Interaction lost with |
| - Retained PPIs, but lost function due to frame-shift fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Interaction lost with |
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Related Drugs for NSD1-FAT2 |
| Drugs targeting genes involved in this fusion gene. (DrugBank Version 5.1.8 2021-05-08) |
| Partner | Gene | UniProtAcc | DrugBank ID | Drug name | Drug activity | Drug type | Drug status |
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Related Diseases for NSD1-FAT2 |
| Diseases associated with fusion partners. (DisGeNet 4.0) |
| Partner | Gene | Disease ID | Disease name | # pubmeds | Source |
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