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Center for Computational Systems Medicine
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Fusion Gene Summary

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Fusion Gene ORF analysis

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Fusion Genomic Features

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Fusion Protein Features

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Fusion Gene Sequence

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Fusion Gene PPI analysis

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Related Drugs

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Related Diseases

Fusion gene:NSFL1C-HOOK2 (FusionGDB2 ID:60480)

Fusion Gene Summary for NSFL1C-HOOK2

check button Fusion gene summary
Fusion gene informationFusion gene name: NSFL1C-HOOK2
Fusion gene ID: 60480
HgeneTgene
Gene symbol

NSFL1C

HOOK2

Gene ID

55968

29911

Gene nameNSFL1 cofactorhook microtubule tethering protein 2
SynonymsP47|UBX1|UBXD10|UBXN2C|dJ776F14.1HK2
Cytomap

20p13

19p13.13

Type of geneprotein-codingprotein-coding
DescriptionNSFL1 cofactor p47NSFL1 (p97) cofactor (p47)SHP1 homologUBX domain-containing protein 2Cp97 cofactor p47protein Hook homolog 2h-hook2hHK2hook homolog 2
Modification date2020031320200327
UniProtAcc.

Q96ED9

Ensembl transtripts involved in fusion geneENST00000216879, ENST00000350991, 
ENST00000353088, ENST00000476071, 
ENST00000381658, ENST00000461211, 
ENST00000589965, ENST00000264827, 
ENST00000397668, 
Fusion gene scores* DoF score4 X 5 X 3=609 X 10 X 6=540
# samples 512
** MAII scorelog2(5/60*10)=-0.263034405833794
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0		log2(12/540*10)=-2.16992500144231
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0
Context

PubMed: NSFL1C [Title/Abstract] AND HOOK2 [Title/Abstract] AND fusion [Title/Abstract]

Most frequent breakpointNSFL1C(1447365)-HOOK2(12885711), # samples:1
Anticipated loss of major functional domain due to fusion event.
* DoF score (Degree of Frequency) = # partners X # break points X # cancer types
** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)

check button Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez
PartnerGeneGO IDGO termPubMed ID

check buttonFusion gene breakpoints across NSFL1C (5'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check buttonFusion gene breakpoints across HOOK2 (3'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check button Fusion gene information from two resources (ChiTars 5.0 and ChimerDB 4.0)
* All genome coordinats were lifted-over on hg19.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
SourceDiseaseSampleHgeneHchrHbpHstrandTgeneTchrTbpTstrand
ChimerDB4SARCTCGA-FX-A48G-01ANSFL1Cchr20

1447365

-HOOK2chr19

12885711

-


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Fusion Gene ORF analysis for NSFL1C-HOOK2

check button Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
ORFHenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrand
5CDS-5UTRENST00000216879ENST00000589965NSFL1Cchr20

1447365

-HOOK2chr19

12885711

-
5CDS-5UTRENST00000350991ENST00000589965NSFL1Cchr20

1447365

-HOOK2chr19

12885711

-
5CDS-5UTRENST00000353088ENST00000589965NSFL1Cchr20

1447365

-HOOK2chr19

12885711

-
5CDS-5UTRENST00000476071ENST00000589965NSFL1Cchr20

1447365

-HOOK2chr19

12885711

-
5UTR-3CDSENST00000381658ENST00000264827NSFL1Cchr20

1447365

-HOOK2chr19

12885711

-
5UTR-3CDSENST00000381658ENST00000397668NSFL1Cchr20

1447365

-HOOK2chr19

12885711

-
5UTR-5UTRENST00000381658ENST00000589965NSFL1Cchr20

1447365

-HOOK2chr19

12885711

-
In-frameENST00000216879ENST00000264827NSFL1Cchr20

1447365

-HOOK2chr19

12885711

-
In-frameENST00000216879ENST00000397668NSFL1Cchr20

1447365

-HOOK2chr19

12885711

-
In-frameENST00000350991ENST00000264827NSFL1Cchr20

1447365

-HOOK2chr19

12885711

-
In-frameENST00000350991ENST00000397668NSFL1Cchr20

1447365

-HOOK2chr19

12885711

-
In-frameENST00000353088ENST00000264827NSFL1Cchr20

1447365

-HOOK2chr19

12885711

-
In-frameENST00000353088ENST00000397668NSFL1Cchr20

1447365

-HOOK2chr19

12885711

-
In-frameENST00000476071ENST00000264827NSFL1Cchr20

1447365

-HOOK2chr19

12885711

-
In-frameENST00000476071ENST00000397668NSFL1Cchr20

1447365

-HOOK2chr19

12885711

-
intron-3CDSENST00000461211ENST00000264827NSFL1Cchr20

1447365

-HOOK2chr19

12885711

-
intron-3CDSENST00000461211ENST00000397668NSFL1Cchr20

1447365

-HOOK2chr19

12885711

-
intron-5UTRENST00000461211ENST00000589965NSFL1Cchr20

1447365

-HOOK2chr19

12885711

-

check buttonORFfinder result based on the fusion transcript sequence of in-frame fusion genes.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandSeq length
(transcript)		BP loci
(transcript)		Predicted start
(transcript)		Predicted stop
(transcript)		Seq length
(amino acids)
ENST00000353088NSFL1Cchr201447365-ENST00000397668HOOK2chr1912885711-250310942223739
ENST00000353088NSFL1Cchr201447365-ENST00000264827HOOK2chr1912885711-249610942217737
ENST00000476071NSFL1Cchr201447365-ENST00000397668HOOK2chr1912885711-2593199942313739
ENST00000476071NSFL1Cchr201447365-ENST00000264827HOOK2chr1912885711-2586199942307737
ENST00000216879NSFL1Cchr201447365-ENST00000397668HOOK2chr1912885711-33679738683087739
ENST00000216879NSFL1Cchr201447365-ENST00000264827HOOK2chr1912885711-33609738683081737
ENST00000350991NSFL1Cchr201447365-ENST00000397668HOOK2chr1912885711-2519125202239739
ENST00000350991NSFL1Cchr201447365-ENST00000264827HOOK2chr1912885711-2512125202233737

check buttonDeepORF prediction of the coding potential based on the fusion transcript sequence of in-frame fusion genes. DeepORF is a coding potential classifier based on convolutional neural network by comparing the real Ribo-seq data. If the no-coding score < 0.5 and coding score > 0.5, then the in-frame fusion transcript is predicted as being likely translated.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandNo-coding scoreCoding score
ENST00000353088ENST00000397668NSFL1Cchr201447365-HOOK2chr1912885711-0.0157464630.9842535
ENST00000353088ENST00000264827NSFL1Cchr201447365-HOOK2chr1912885711-0.0161534920.98384655
ENST00000476071ENST00000397668NSFL1Cchr201447365-HOOK2chr1912885711-0.0162537560.9837463
ENST00000476071ENST00000264827NSFL1Cchr201447365-HOOK2chr1912885711-0.0167046880.98329526
ENST00000216879ENST00000397668NSFL1Cchr201447365-HOOK2chr1912885711-0.0221490150.977851
ENST00000216879ENST00000264827NSFL1Cchr201447365-HOOK2chr1912885711-0.022735220.97726476
ENST00000350991ENST00000397668NSFL1Cchr201447365-HOOK2chr1912885711-0.0158199650.98418
ENST00000350991ENST00000264827NSFL1Cchr201447365-HOOK2chr1912885711-0.0162068180.9837932

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Fusion Genomic Features for NSFL1C-HOOK2


check buttonFusionAI prediction of the potential fusion gene breakpoint based on the pre-mature RNA sequence context (+/- 5kb of individual partner genes, total 20kb length sequence). FusionAI is a fusion gene breakpoint classifier based on convolutional neural network by comparing the fusion positive and negative sequence context of ~ 20K fusion gene data. From here, we can have the relative potentency of the 20K genomic sequence how individual sequnce will be likely used as the gene fusion breakpoints.
HgeneHchrHbpHstrandTgeneTchrTbpTstrand1-pp (fusion gene breakpoint)

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions. We integrated a total of 44 different types of human genomic feature loci information across five big categories including virus integration sites, repeats, structural variants, chromatin states, and gene expression regulation. More details are in help page.
genomic feature

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions that are ovelapped with the top 1% feature importance score regions. More details are in help page.

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Fusion Protein Features for NSFL1C-HOOK2


check button Four levels of functional features of fusion genes
Go to FGviewer search page for the most frequent breakpoint (https://ccsmweb.uth.edu/FGviewer/chr20:1447365/chr19:12885711)
- FGviewer provides the online visualization of the retention search of the protein functional features across DNA, RNA, protein, and pathological levels.
- How to search
1. Put your fusion gene symbol.
2. Press the tab key until there will be shown the breakpoint information filled.
4. Go down and press 'Search' tab twice.
4. Go down to have the hyperlink of the search result.
5. Click the hyperlink.
6. See the FGviewer result for your fusion gene.
FGviewer

check buttonMain function of each fusion partner protein. (from UniProt)
HgeneTgene
.HOOK2

Q96ED9

FUNCTION: Transcriptional activator which is required for calcium-dependent dendritic growth and branching in cortical neurons. Recruits CREB-binding protein (CREBBP) to nuclear bodies. Component of the CREST-BRG1 complex, a multiprotein complex that regulates promoter activation by orchestrating a calcium-dependent release of a repressor complex and a recruitment of an activator complex. In resting neurons, transcription of the c-FOS promoter is inhibited by BRG1-dependent recruitment of a phospho-RB1-HDAC1 repressor complex. Upon calcium influx, RB1 is dephosphorylated by calcineurin, which leads to release of the repressor complex. At the same time, there is increased recruitment of CREBBP to the promoter by a CREST-dependent mechanism, which leads to transcriptional activation. The CREST-BRG1 complex also binds to the NR2B promoter, and activity-dependent induction of NR2B expression involves a release of HDAC1 and recruitment of CREBBP (By similarity). {ECO:0000250}.FUNCTION: Component of the FTS/Hook/FHIP complex (FHF complex). The FHF complex may function to promote vesicle trafficking and/or fusion via the homotypic vesicular protein sorting complex (the HOPS complex). Contributes to the establishment and maintenance of centrosome function. May function in the positioning or formation of aggresomes, which are pericentriolar accumulations of misfolded proteins, proteasomes and chaperones. {ECO:0000269|PubMed:17140400, ECO:0000269|PubMed:17540036, ECO:0000269|PubMed:18799622}.

check buttonRetention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at

download page


* Minus value of BPloci means that the break pointn is located before the CDS.
- In-frame and retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
TgeneHOOK2chr20:1447365chr19:12885711ENST00000264827022180_42715718.0Coiled coilOntology_term=ECO:0000255
TgeneHOOK2chr20:1447365chr19:12885711ENST00000264827022455_60715718.0Coiled coilOntology_term=ECO:0000255
TgeneHOOK2chr20:1447365chr19:12885711ENST00000397668023180_42715720.0Coiled coilOntology_term=ECO:0000255
TgeneHOOK2chr20:1447365chr19:12885711ENST00000397668023455_60715720.0Coiled coilOntology_term=ECO:0000255
TgeneHOOK2chr20:1447365chr19:12885711ENST00000264827022533_71915718.0RegionNote=Required for localization to the centrosome and induction of aggresome formation
TgeneHOOK2chr20:1447365chr19:12885711ENST00000397668023533_71915720.0RegionNote=Required for localization to the centrosome and induction of aggresome formation

- In-frame and not-retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneNSFL1Cchr20:1447365chr19:12885711ENST00000216879-1984_9035371.0Compositional biasNote=Poly-Glu
HgeneNSFL1Cchr20:1447365chr19:12885711ENST00000353088-1884_9035340.0Compositional biasNote=Poly-Glu
HgeneNSFL1Cchr20:1447365chr19:12885711ENST00000381658-1884_900260.0Compositional biasNote=Poly-Glu
HgeneNSFL1Cchr20:1447365chr19:12885711ENST00000476071-11084_9035373.0Compositional biasNote=Poly-Glu
HgeneNSFL1Cchr20:1447365chr19:12885711ENST00000216879-19179_24435371.0DomainSEP
HgeneNSFL1Cchr20:1447365chr19:12885711ENST00000216879-19291_36835371.0DomainUBX
HgeneNSFL1Cchr20:1447365chr19:12885711ENST00000353088-18179_24435340.0DomainSEP
HgeneNSFL1Cchr20:1447365chr19:12885711ENST00000353088-18291_36835340.0DomainUBX
HgeneNSFL1Cchr20:1447365chr19:12885711ENST00000381658-18179_2440260.0DomainSEP
HgeneNSFL1Cchr20:1447365chr19:12885711ENST00000381658-18291_3680260.0DomainUBX
HgeneNSFL1Cchr20:1447365chr19:12885711ENST00000476071-110179_24435373.0DomainSEP
HgeneNSFL1Cchr20:1447365chr19:12885711ENST00000476071-110291_36835373.0DomainUBX
HgeneNSFL1Cchr20:1447365chr19:12885711ENST00000216879-19109_11535371.0MotifNote=Nuclear localization signal
HgeneNSFL1Cchr20:1447365chr19:12885711ENST00000216879-19172_17535371.0MotifNote=Nuclear localization signal
HgeneNSFL1Cchr20:1447365chr19:12885711ENST00000353088-18109_11535340.0MotifNote=Nuclear localization signal
HgeneNSFL1Cchr20:1447365chr19:12885711ENST00000353088-18172_17535340.0MotifNote=Nuclear localization signal
HgeneNSFL1Cchr20:1447365chr19:12885711ENST00000381658-18109_1150260.0MotifNote=Nuclear localization signal
HgeneNSFL1Cchr20:1447365chr19:12885711ENST00000381658-18172_1750260.0MotifNote=Nuclear localization signal
HgeneNSFL1Cchr20:1447365chr19:12885711ENST00000476071-110109_11535373.0MotifNote=Nuclear localization signal
HgeneNSFL1Cchr20:1447365chr19:12885711ENST00000476071-110172_17535373.0MotifNote=Nuclear localization signal
TgeneHOOK2chr20:1447365chr19:12885711ENST000002648270226_12215718.0DomainCalponin-homology (CH)
TgeneHOOK2chr20:1447365chr19:12885711ENST000003976680236_12215720.0DomainCalponin-homology (CH)
TgeneHOOK2chr20:1447365chr19:12885711ENST000002648270221_16115718.0RegionNote=Required for localization to the centrosome and induction of aggresome formation
TgeneHOOK2chr20:1447365chr19:12885711ENST000003976680231_16115720.0RegionNote=Required for localization to the centrosome and induction of aggresome formation


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Fusion Gene Sequence for NSFL1C-HOOK2


check button For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. To have fusion amino acid sequence, we ran ORFfinder and chose the longest ORF among the all predicted ones.
>60480_60480_1_NSFL1C-HOOK2_NSFL1C_chr20_1447365_ENST00000216879_HOOK2_chr19_12885711_ENST00000264827_length(transcript)=3360nt_BP=973nt
AAGTTCCTCTTTGGAGAGGCAAGAGGGCAAAGAAGCTGAGGACCCAGAAGACAGGATTGTGCCTAAGAAAGTGGCCTTGGAGCAGAGGCC
CAAAGAAAGCGGGGAGAGCGCCTTGCCCATCGGTAAGGGAAAGGTGCTCCAGGCACAGAAGCAGCTAATGCAACGGCCCTGAGGCAAATG
CAAGATAACTGGCAAGTTCCAGGAACAGCAAGGAGGGCAAGGCGCCTGGAGCAGAGGAAGCTAGCGGATCCCTTGATGAGAGGGAGGAAC
TGGCCCATCTCTCATGGGTCCTGCAGGCAGGCCATGAGACTGTCTTTTATGCGGGGCGAGATAACGAGGCATGGACGTGTTGTGAGCGGA
GGCCTAGCCTGTTCAAGGTCTGAATTTTTACCCCTAGAATGTAAGAAGCATGGGAGCAGGGACTTTGTTTTGCTCCCTGCCATATCCACA
GCCCTAGAAAAACGTCGGGCCATTGATAGCTCTCAGTAAATGCTTGACAAGTAAGTGAATGAACGAATGCACAATTAATGAAATGAGGGC
TGCGTCAATGAATAACTGGGAATCTGACTCCTGCAGGGAGCCTTCAGCCCACAGGTGTATGTAAGACCCGCCCCGCCTCTCATCCTTCGG
GCTCCCACCCCCGCCGTTAGGCTGCGGTTCGCGCCGCGGTCGCCAGAGGGCGCGGAGCGGCGGGGCTTCCCGCACGGAGGGCTTTGCGTG
AGGCACCGCGTGGGGCGGGGCTGCGGGCGGGCTCCCAGCTGCTGGGCCCTCATCGGCTGGGCCTCGTCGACCGGCAAGCGGAACGCGGCA
GCGGGGCTGGGCCTGTGCGGCGGCCGCCGGAGCGCTTTGGAAGGCGCACGGGGCGAAGATGGCGGCGGAGCGACAGGAGGCGCTGAGGGA
GTTCGTGGCGGTGACGGGCGCCGAGGAGGACCGGGCCCGCTTCTTTCTCGAGTCGGCCGGCTGGGACTTGCAGTTACAGACGTTCCACGT
TCCGTCTCCCTGTGCCAGCCCTCAGGACCTGAGCAGCGGCCTTGCCGTAGCCTATGTGCTGAACCAGATAGACCCCTCCTGGTTCAACGA
GGCATGGCTCCAGGGCATCTCGGAAGATCCAGGTCCCAACTGGAAGCTGAAGGTCAGCAATCTGAAGATGGTCTTACGGAGCCTAGTAGA
GTACTCCCAGGATGTCCTGGCGCATCCTGTGTCAGAAGAGCATCTCCCAGATGTGAGCCTCATTGGAGAGTTCTCAGACCCGGCAGAGCT
CGGCAAGCTGCTTCAGCTGGTGCTGGGCTGTGCCATCAGTTGCGAGAAAAAGCAGGACCACATCCAGAGAATCATGACGCTGGAAGAATC
GGTTCAGCATGTGGTGATGGAAGCCATCCAAGAGCTCATGACCAAAGACACTCCTGACTCCCTGTCACCAGAGACGTATGGCAACTTTGA
CAGCCAGTCCCGCAGGTACTATTTCCTAAGTGAGGAGGCTGAGGAGGGGGACGAATTACAGCAGCGCTGTCTGGATCTGGAGCGGCAGCT
GATGCTCCTGTCAGAGGAGAAGCAGAGCCTGGCGCAAGAGAATGCAGGGCTGCGGGAGCGGATGGGCCGGCCTGAAGGCGAGGGTACCCC
AGGTCTCACTGCCAAGAAGCTGCTGCTGCTGCAATCCCAGCTGGAGCAGTTGCAGGAGGAGAACTTCAGGCTGGAGAGTGGCAGGGAGGA
TGAGCGCCTGCGCTGTGCCGAGCTGGAGAGGGAGGTTGCGGAGCTGCAGCACCGGAACCAGGCGCTGACTAGCCTGGCCCAGGAGGCACA
GGCCCTGAAGGATGAGATGGATGAACTACGGCAGTCTTCGGAGCGTGCTGGGCAGCTGGAGGCCACGCTGACCAGTTGCCGGCGCCGCTT
GGGCGAGCTGAGGGAGCTGCGGCGGCAGGTGCGGCAGCTGGAGGAACGCAACGCCGGCCACGCCGAGCGCACGCGACAACTGGAGGATGA
GCTACGCCGAGCGGGCTCCCTGCGCGCCCAGCTGGAGGCGCAGCGGCGGCAGGTGCAGGAACTGCAGGGCCAGCGGCAGGAGGAGGCCAT
GAAGGCCGAGAAATGGCTATTTGAATGCCGCAACCTGGAGGAAAAGTATGAGTCGGTGACAAAGGAGAAGGAGCGGCTGTTGGCGGAGCG
GGACTCCTTGCGGGAGGCCAATGAGGAGCTGCGCTGCGCCCAGCTGCAGCCGCGGGGGTTGACCCAGGCCGATCCCTCACTGGATCCCAC
CTCCACACCCGTGGATAACTTAGCCGCAGAGATCCTGCCTGCGGAGCTCAGGGAGACGCTCCTGCGGCTTCAGCTGGAGAACAAGCGGCT
GTGCAGGCAGGAGGCGGCCGACCGGGAGCGGCAGGAGGAGCTGCAGCGCCACCTGGAGGATGCCAACCGCGCGCGCCACGGGTTGGAGAC
GCAGCACCGGCTGAACCAGCAGCAGCTATCCGAGCTGCGGGCCCAGGTGGAGGACCTGCAGAAAGCCCTGCAGGAGCAGGGGGGCAAGAC
TGAAGATTCCATTTTGCTGAAAAGGAAGCTGGAGGAACATTTGCAGAAGCTTCATGAGGCAGATCTGGAGTTGCAGAGGAAGCGGGAGTA
CATTGAGGAGCTGGAGCCACCCACTGACAGCAGCACAGCCCGGCGGATCGAGGAGCTGCAGCATAACTTGCAGAAGAAGGACGCGGACTT
GCGGGCCATGGAGGAGCGATACCGCCGCTACGTGGACAAGGCCCGCATGGTCATGCAGACCATGGAACCCAAGCAGCGGCCAGCTGCGGG
GGCACCTCCAGAACTCCATTCCCTGAGGACACAGCTCCGAGAACGGGATGTCCGCATCCGACACCTGGAGATGGACTTTGAGAAAAGCCG
AAGTCAGCGGGAGCAGGAAGAAAAGCTGCTCATCAGTGCCTGGTATAATATGGGCATGGCCTTGCAGCAGCGAGCTGGGGAGGAGCGGGC
GCCTGCCCATGCCCAGTCATTCCTGGCACAGCAGCGGCTGGCAACCAATTCTCGCCGTGGACCCTTGGGACGCCTGGCATCTCTGAACCT
TCGCCCCACTGACAAGCACTGACAGACCTCACAATCAAGCCAGCCTGGGCTCCACCCACCCTGGCTTCCTCCAGCTCACATGGCGCCCAG
CACTGGGCTTCAGCCAGGTGCTCGAGAGCTTTGAGGCCATGATCTCTGCTCTTCCCTCTCCCAGATTGGTGGGGAGGGAGGGCGGGAGGT
AGATATAGGCCTGTTCTTTTTAGCAATGTGATTCTTGTTGTTGATTCTCTCTCTGGAGTTCATGTGCTGCCTCAGGAGACTCTGATTTTA

>60480_60480_1_NSFL1C-HOOK2_NSFL1C_chr20_1447365_ENST00000216879_HOOK2_chr19_12885711_ENST00000264827_length(amino acids)=737AA_BP=34
MAAERQEALREFVAVTGAEEDRARFFLESAGWDLQLQTFHVPSPCASPQDLSSGLAVAYVLNQIDPSWFNEAWLQGISEDPGPNWKLKVS
NLKMVLRSLVEYSQDVLAHPVSEEHLPDVSLIGEFSDPAELGKLLQLVLGCAISCEKKQDHIQRIMTLEESVQHVVMEAIQELMTKDTPD
SLSPETYGNFDSQSRRYYFLSEEAEEGDELQQRCLDLERQLMLLSEEKQSLAQENAGLRERMGRPEGEGTPGLTAKKLLLLQSQLEQLQE
ENFRLESGREDERLRCAELEREVAELQHRNQALTSLAQEAQALKDEMDELRQSSERAGQLEATLTSCRRRLGELRELRRQVRQLEERNAG
HAERTRQLEDELRRAGSLRAQLEAQRRQVQELQGQRQEEAMKAEKWLFECRNLEEKYESVTKEKERLLAERDSLREANEELRCAQLQPRG
LTQADPSLDPTSTPVDNLAAEILPAELRETLLRLQLENKRLCRQEAADRERQEELQRHLEDANRARHGLETQHRLNQQQLSELRAQVEDL
QKALQEQGGKTEDSILLKRKLEEHLQKLHEADLELQRKREYIEELEPPTDSSTARRIEELQHNLQKKDADLRAMEERYRRYVDKARMVMQ
TMEPKQRPAAGAPPELHSLRTQLRERDVRIRHLEMDFEKSRSQREQEEKLLISAWYNMGMALQQRAGEERAPAHAQSFLAQQRLATNSRR

--------------------------------------------------------------
>60480_60480_2_NSFL1C-HOOK2_NSFL1C_chr20_1447365_ENST00000216879_HOOK2_chr19_12885711_ENST00000397668_length(transcript)=3367nt_BP=973nt
AAGTTCCTCTTTGGAGAGGCAAGAGGGCAAAGAAGCTGAGGACCCAGAAGACAGGATTGTGCCTAAGAAAGTGGCCTTGGAGCAGAGGCC
CAAAGAAAGCGGGGAGAGCGCCTTGCCCATCGGTAAGGGAAAGGTGCTCCAGGCACAGAAGCAGCTAATGCAACGGCCCTGAGGCAAATG
CAAGATAACTGGCAAGTTCCAGGAACAGCAAGGAGGGCAAGGCGCCTGGAGCAGAGGAAGCTAGCGGATCCCTTGATGAGAGGGAGGAAC
TGGCCCATCTCTCATGGGTCCTGCAGGCAGGCCATGAGACTGTCTTTTATGCGGGGCGAGATAACGAGGCATGGACGTGTTGTGAGCGGA
GGCCTAGCCTGTTCAAGGTCTGAATTTTTACCCCTAGAATGTAAGAAGCATGGGAGCAGGGACTTTGTTTTGCTCCCTGCCATATCCACA
GCCCTAGAAAAACGTCGGGCCATTGATAGCTCTCAGTAAATGCTTGACAAGTAAGTGAATGAACGAATGCACAATTAATGAAATGAGGGC
TGCGTCAATGAATAACTGGGAATCTGACTCCTGCAGGGAGCCTTCAGCCCACAGGTGTATGTAAGACCCGCCCCGCCTCTCATCCTTCGG
GCTCCCACCCCCGCCGTTAGGCTGCGGTTCGCGCCGCGGTCGCCAGAGGGCGCGGAGCGGCGGGGCTTCCCGCACGGAGGGCTTTGCGTG
AGGCACCGCGTGGGGCGGGGCTGCGGGCGGGCTCCCAGCTGCTGGGCCCTCATCGGCTGGGCCTCGTCGACCGGCAAGCGGAACGCGGCA
GCGGGGCTGGGCCTGTGCGGCGGCCGCCGGAGCGCTTTGGAAGGCGCACGGGGCGAAGATGGCGGCGGAGCGACAGGAGGCGCTGAGGGA
GTTCGTGGCGGTGACGGGCGCCGAGGAGGACCGGGCCCGCTTCTTTCTCGAGTCGGCCGGCTGGGACTTGCAGTTACAGACGTTCCACGT
TCCGTCTCCCTGTGCCAGCCCTCAGGACCTGAGCAGCGGCCTTGCCGTAGCCTATGTGCTGAACCAGATAGACCCCTCCTGGTTCAACGA
GGCATGGCTCCAGGGCATCTCGGAAGATCCAGGTCCCAACTGGAAGCTGAAGGTCAGCAATCTGAAGATGGTCTTACGGAGCCTAGTAGA
GTACTCCCAGGATGTCCTGGCGCATCCTGTGTCAGAAGAGCATCTCCCAGATGTGAGCCTCATTGGAGAGTTCTCAGACCCGGCAGAGCT
CGGCAAGCTGCTTCAGCTGGTGCTGGGCTGTGCCATCAGTTGCGAGAAAAAGCAGGACCACATCCAGAGAATCATGACGCTGGAAGAATC
GGTTCAGCATGTGGTGATGGAAGCCATCCAAGAGCTCATGACCAAAGACACTCCTGACTCCCTGTCACCAGAGACGTATGGCAACTTTGA
CAGCCAGTCCCGCAGGTACTATTTCCTAAGTGAGGAGGCTGAGGAGGGGGACGAATTACAGCAGCGCTGTCTGGATCTGGAGCGGCAGCT
GATGCTCCTGTCAGAGGAGAAGCAGAGCCTGGCGCAAGAGAATGCAGGGCTGCGGGAGCGGATGGGCCGGCCTGAAGGCGAGGGTACCCC
AGGTCTCACTGCCAAGAAGCTGCTGCTGCTGCAATCCCAGCTGGAGCAGTTGCAGGAGGAGAACTTCAGGCTGGAGAGTGGCAGGGAGGA
TGAGCGCCTGCGCTGTGCCGAGCTGGAGAGGGAGGTTGCGGAGCTGCAGCACCGGAACCAGGCGCTGACTAGCCTGGCCCAGGAGGCACA
GGCCCTGAAGGATGAGATGGATGAACTACGGCAGTCTTCGGAGCGTGCTGGGCAGCTGGAGGCCACGCTGACCAGTTGCCGGCGCCGCTT
GGGCGAGCTGAGGGAGCTGCGGCGGCAGGTGCGGCAGCTGGAGGAACGCAACGCCGGCCACGCCGAGCGCACGCGACAACTGGAGGATGA
GCTACGCCGAGCGGGCTCCCTGCGCGCCCAGCTGGAGGCGCAGCGGCGGCAGGTGCAGGAACTGCAGGGCCAGCGGCAGGAGGAGGCCAT
GAAGGCCGAGAAATGGCTATTTGAATGCCGCAACCTGGAGGAAAAGTATGAGTCGGTGACAAAGGAGAAGGAGCGGCTGTTGGCGGAGCG
GGACTCCTTGCGGGAGGCCAATGAGGAGCTGCGCTGCGCCCAGCTGCAGCCGCGGGGGTTGACCCAGGCCGATCCCTCACTGGATCCCAC
CTCCACACCCGTGGATAACTTAGCCGCAGAGATCCTGCCTGCGGAGCTCAGGGAGACGCTCCTGCGGCTTCAGCTGGAGAACAAGCGGCT
GTGCAGGCAGGAGGCGGCCGACCGGGAGCGGCAGGAGGAGCTGCAGCGCCACCTGGAGGATGCCAACCGCGCGCGCCACGGGTTGGAGAC
GCAGCACCGGCTGAACCAGCAGCAGCTATCCGAGCTGCGGGCCCAGGTGGAGGACCTGCAGAAAGCCCTGCAGGAGCAGGGGGGCAAGAC
TGAAGATGCCATTTCCATTTTGCTGAAAAGGAAGCTGGAGGAACATTTGCAGAAGCTTCATGAGGCAGATCTGGAGTTGCAGAGGAAGCG
GGAGTACATTGAGGAGCTGGAGCCACCCACTGACAGCAGCACAGCCCGGCGGATCGAGGAGCTGCAGCATAACTTGCAGAAGAAGGACGC
GGACTTGCGGGCCATGGAGGAGCGATACCGCCGCTACGTGGACAAGGCCCGCATGGTCATGCAGACCATGGAACCCAAGCAGCGGCCAGC
TGCGGGGGCACCTCCAGAACTCCATTCCCTGAGGACACAGCTCCGAGAACGGGATGTCCGCATCCGACACCTGGAGATGGACTTTGAGAA
AAGCCGAAGTCAGCGGGAGCAGGAAGAAAAGCTGCTCATCAGTGCCTGGTATAATATGGGCATGGCCTTGCAGCAGCGAGCTGGGGAGGA
GCGGGCGCCTGCCCATGCCCAGTCATTCCTGGCACAGCAGCGGCTGGCAACCAATTCTCGCCGTGGACCCTTGGGACGCCTGGCATCTCT
GAACCTTCGCCCCACTGACAAGCACTGACAGACCTCACAATCAAGCCAGCCTGGGCTCCACCCACCCTGGCTTCCTCCAGCTCACATGGC
GCCCAGCACTGGGCTTCAGCCAGGTGCTCGAGAGCTTTGAGGCCATGATCTCTGCTCTTCCCTCTCCCAGATTGGTGGGGAGGGAGGGCG
GGAGGTAGATATAGGCCTGTTCTTTTTAGCAATGTGATTCTTGTTGTTGATTCTCTCTCTGGAGTTCATGTGCTGCCTCAGGAGACTCTG

>60480_60480_2_NSFL1C-HOOK2_NSFL1C_chr20_1447365_ENST00000216879_HOOK2_chr19_12885711_ENST00000397668_length(amino acids)=739AA_BP=34
MAAERQEALREFVAVTGAEEDRARFFLESAGWDLQLQTFHVPSPCASPQDLSSGLAVAYVLNQIDPSWFNEAWLQGISEDPGPNWKLKVS
NLKMVLRSLVEYSQDVLAHPVSEEHLPDVSLIGEFSDPAELGKLLQLVLGCAISCEKKQDHIQRIMTLEESVQHVVMEAIQELMTKDTPD
SLSPETYGNFDSQSRRYYFLSEEAEEGDELQQRCLDLERQLMLLSEEKQSLAQENAGLRERMGRPEGEGTPGLTAKKLLLLQSQLEQLQE
ENFRLESGREDERLRCAELEREVAELQHRNQALTSLAQEAQALKDEMDELRQSSERAGQLEATLTSCRRRLGELRELRRQVRQLEERNAG
HAERTRQLEDELRRAGSLRAQLEAQRRQVQELQGQRQEEAMKAEKWLFECRNLEEKYESVTKEKERLLAERDSLREANEELRCAQLQPRG
LTQADPSLDPTSTPVDNLAAEILPAELRETLLRLQLENKRLCRQEAADRERQEELQRHLEDANRARHGLETQHRLNQQQLSELRAQVEDL
QKALQEQGGKTEDAISILLKRKLEEHLQKLHEADLELQRKREYIEELEPPTDSSTARRIEELQHNLQKKDADLRAMEERYRRYVDKARMV
MQTMEPKQRPAAGAPPELHSLRTQLRERDVRIRHLEMDFEKSRSQREQEEKLLISAWYNMGMALQQRAGEERAPAHAQSFLAQQRLATNS

--------------------------------------------------------------
>60480_60480_3_NSFL1C-HOOK2_NSFL1C_chr20_1447365_ENST00000350991_HOOK2_chr19_12885711_ENST00000264827_length(transcript)=2512nt_BP=125nt
GGAAGGCGCACGGGGCGAAGATGGCGGCGGAGCGACAGGAGGCGCTGAGGGAGTTCGTGGCGGTGACGGGCGCCGAGGAGGACCGGGCCC
GCTTCTTTCTCGAGTCGGCCGGCTGGGACTTGCAGTTACAGACGTTCCACGTTCCGTCTCCCTGTGCCAGCCCTCAGGACCTGAGCAGCG
GCCTTGCCGTAGCCTATGTGCTGAACCAGATAGACCCCTCCTGGTTCAACGAGGCATGGCTCCAGGGCATCTCGGAAGATCCAGGTCCCA
ACTGGAAGCTGAAGGTCAGCAATCTGAAGATGGTCTTACGGAGCCTAGTAGAGTACTCCCAGGATGTCCTGGCGCATCCTGTGTCAGAAG
AGCATCTCCCAGATGTGAGCCTCATTGGAGAGTTCTCAGACCCGGCAGAGCTCGGCAAGCTGCTTCAGCTGGTGCTGGGCTGTGCCATCA
GTTGCGAGAAAAAGCAGGACCACATCCAGAGAATCATGACGCTGGAAGAATCGGTTCAGCATGTGGTGATGGAAGCCATCCAAGAGCTCA
TGACCAAAGACACTCCTGACTCCCTGTCACCAGAGACGTATGGCAACTTTGACAGCCAGTCCCGCAGGTACTATTTCCTAAGTGAGGAGG
CTGAGGAGGGGGACGAATTACAGCAGCGCTGTCTGGATCTGGAGCGGCAGCTGATGCTCCTGTCAGAGGAGAAGCAGAGCCTGGCGCAAG
AGAATGCAGGGCTGCGGGAGCGGATGGGCCGGCCTGAAGGCGAGGGTACCCCAGGTCTCACTGCCAAGAAGCTGCTGCTGCTGCAATCCC
AGCTGGAGCAGTTGCAGGAGGAGAACTTCAGGCTGGAGAGTGGCAGGGAGGATGAGCGCCTGCGCTGTGCCGAGCTGGAGAGGGAGGTTG
CGGAGCTGCAGCACCGGAACCAGGCGCTGACTAGCCTGGCCCAGGAGGCACAGGCCCTGAAGGATGAGATGGATGAACTACGGCAGTCTT
CGGAGCGTGCTGGGCAGCTGGAGGCCACGCTGACCAGTTGCCGGCGCCGCTTGGGCGAGCTGAGGGAGCTGCGGCGGCAGGTGCGGCAGC
TGGAGGAACGCAACGCCGGCCACGCCGAGCGCACGCGACAACTGGAGGATGAGCTACGCCGAGCGGGCTCCCTGCGCGCCCAGCTGGAGG
CGCAGCGGCGGCAGGTGCAGGAACTGCAGGGCCAGCGGCAGGAGGAGGCCATGAAGGCCGAGAAATGGCTATTTGAATGCCGCAACCTGG
AGGAAAAGTATGAGTCGGTGACAAAGGAGAAGGAGCGGCTGTTGGCGGAGCGGGACTCCTTGCGGGAGGCCAATGAGGAGCTGCGCTGCG
CCCAGCTGCAGCCGCGGGGGTTGACCCAGGCCGATCCCTCACTGGATCCCACCTCCACACCCGTGGATAACTTAGCCGCAGAGATCCTGC
CTGCGGAGCTCAGGGAGACGCTCCTGCGGCTTCAGCTGGAGAACAAGCGGCTGTGCAGGCAGGAGGCGGCCGACCGGGAGCGGCAGGAGG
AGCTGCAGCGCCACCTGGAGGATGCCAACCGCGCGCGCCACGGGTTGGAGACGCAGCACCGGCTGAACCAGCAGCAGCTATCCGAGCTGC
GGGCCCAGGTGGAGGACCTGCAGAAAGCCCTGCAGGAGCAGGGGGGCAAGACTGAAGATTCCATTTTGCTGAAAAGGAAGCTGGAGGAAC
ATTTGCAGAAGCTTCATGAGGCAGATCTGGAGTTGCAGAGGAAGCGGGAGTACATTGAGGAGCTGGAGCCACCCACTGACAGCAGCACAG
CCCGGCGGATCGAGGAGCTGCAGCATAACTTGCAGAAGAAGGACGCGGACTTGCGGGCCATGGAGGAGCGATACCGCCGCTACGTGGACA
AGGCCCGCATGGTCATGCAGACCATGGAACCCAAGCAGCGGCCAGCTGCGGGGGCACCTCCAGAACTCCATTCCCTGAGGACACAGCTCC
GAGAACGGGATGTCCGCATCCGACACCTGGAGATGGACTTTGAGAAAAGCCGAAGTCAGCGGGAGCAGGAAGAAAAGCTGCTCATCAGTG
CCTGGTATAATATGGGCATGGCCTTGCAGCAGCGAGCTGGGGAGGAGCGGGCGCCTGCCCATGCCCAGTCATTCCTGGCACAGCAGCGGC
TGGCAACCAATTCTCGCCGTGGACCCTTGGGACGCCTGGCATCTCTGAACCTTCGCCCCACTGACAAGCACTGACAGACCTCACAATCAA
GCCAGCCTGGGCTCCACCCACCCTGGCTTCCTCCAGCTCACATGGCGCCCAGCACTGGGCTTCAGCCAGGTGCTCGAGAGCTTTGAGGCC
ATGATCTCTGCTCTTCCCTCTCCCAGATTGGTGGGGAGGGAGGGCGGGAGGTAGATATAGGCCTGTTCTTTTTAGCAATGTGATTCTTGT

>60480_60480_3_NSFL1C-HOOK2_NSFL1C_chr20_1447365_ENST00000350991_HOOK2_chr19_12885711_ENST00000264827_length(amino acids)=737AA_BP=34
MAAERQEALREFVAVTGAEEDRARFFLESAGWDLQLQTFHVPSPCASPQDLSSGLAVAYVLNQIDPSWFNEAWLQGISEDPGPNWKLKVS
NLKMVLRSLVEYSQDVLAHPVSEEHLPDVSLIGEFSDPAELGKLLQLVLGCAISCEKKQDHIQRIMTLEESVQHVVMEAIQELMTKDTPD
SLSPETYGNFDSQSRRYYFLSEEAEEGDELQQRCLDLERQLMLLSEEKQSLAQENAGLRERMGRPEGEGTPGLTAKKLLLLQSQLEQLQE
ENFRLESGREDERLRCAELEREVAELQHRNQALTSLAQEAQALKDEMDELRQSSERAGQLEATLTSCRRRLGELRELRRQVRQLEERNAG
HAERTRQLEDELRRAGSLRAQLEAQRRQVQELQGQRQEEAMKAEKWLFECRNLEEKYESVTKEKERLLAERDSLREANEELRCAQLQPRG
LTQADPSLDPTSTPVDNLAAEILPAELRETLLRLQLENKRLCRQEAADRERQEELQRHLEDANRARHGLETQHRLNQQQLSELRAQVEDL
QKALQEQGGKTEDSILLKRKLEEHLQKLHEADLELQRKREYIEELEPPTDSSTARRIEELQHNLQKKDADLRAMEERYRRYVDKARMVMQ
TMEPKQRPAAGAPPELHSLRTQLRERDVRIRHLEMDFEKSRSQREQEEKLLISAWYNMGMALQQRAGEERAPAHAQSFLAQQRLATNSRR

--------------------------------------------------------------
>60480_60480_4_NSFL1C-HOOK2_NSFL1C_chr20_1447365_ENST00000350991_HOOK2_chr19_12885711_ENST00000397668_length(transcript)=2519nt_BP=125nt
GGAAGGCGCACGGGGCGAAGATGGCGGCGGAGCGACAGGAGGCGCTGAGGGAGTTCGTGGCGGTGACGGGCGCCGAGGAGGACCGGGCCC
GCTTCTTTCTCGAGTCGGCCGGCTGGGACTTGCAGTTACAGACGTTCCACGTTCCGTCTCCCTGTGCCAGCCCTCAGGACCTGAGCAGCG
GCCTTGCCGTAGCCTATGTGCTGAACCAGATAGACCCCTCCTGGTTCAACGAGGCATGGCTCCAGGGCATCTCGGAAGATCCAGGTCCCA
ACTGGAAGCTGAAGGTCAGCAATCTGAAGATGGTCTTACGGAGCCTAGTAGAGTACTCCCAGGATGTCCTGGCGCATCCTGTGTCAGAAG
AGCATCTCCCAGATGTGAGCCTCATTGGAGAGTTCTCAGACCCGGCAGAGCTCGGCAAGCTGCTTCAGCTGGTGCTGGGCTGTGCCATCA
GTTGCGAGAAAAAGCAGGACCACATCCAGAGAATCATGACGCTGGAAGAATCGGTTCAGCATGTGGTGATGGAAGCCATCCAAGAGCTCA
TGACCAAAGACACTCCTGACTCCCTGTCACCAGAGACGTATGGCAACTTTGACAGCCAGTCCCGCAGGTACTATTTCCTAAGTGAGGAGG
CTGAGGAGGGGGACGAATTACAGCAGCGCTGTCTGGATCTGGAGCGGCAGCTGATGCTCCTGTCAGAGGAGAAGCAGAGCCTGGCGCAAG
AGAATGCAGGGCTGCGGGAGCGGATGGGCCGGCCTGAAGGCGAGGGTACCCCAGGTCTCACTGCCAAGAAGCTGCTGCTGCTGCAATCCC
AGCTGGAGCAGTTGCAGGAGGAGAACTTCAGGCTGGAGAGTGGCAGGGAGGATGAGCGCCTGCGCTGTGCCGAGCTGGAGAGGGAGGTTG
CGGAGCTGCAGCACCGGAACCAGGCGCTGACTAGCCTGGCCCAGGAGGCACAGGCCCTGAAGGATGAGATGGATGAACTACGGCAGTCTT
CGGAGCGTGCTGGGCAGCTGGAGGCCACGCTGACCAGTTGCCGGCGCCGCTTGGGCGAGCTGAGGGAGCTGCGGCGGCAGGTGCGGCAGC
TGGAGGAACGCAACGCCGGCCACGCCGAGCGCACGCGACAACTGGAGGATGAGCTACGCCGAGCGGGCTCCCTGCGCGCCCAGCTGGAGG
CGCAGCGGCGGCAGGTGCAGGAACTGCAGGGCCAGCGGCAGGAGGAGGCCATGAAGGCCGAGAAATGGCTATTTGAATGCCGCAACCTGG
AGGAAAAGTATGAGTCGGTGACAAAGGAGAAGGAGCGGCTGTTGGCGGAGCGGGACTCCTTGCGGGAGGCCAATGAGGAGCTGCGCTGCG
CCCAGCTGCAGCCGCGGGGGTTGACCCAGGCCGATCCCTCACTGGATCCCACCTCCACACCCGTGGATAACTTAGCCGCAGAGATCCTGC
CTGCGGAGCTCAGGGAGACGCTCCTGCGGCTTCAGCTGGAGAACAAGCGGCTGTGCAGGCAGGAGGCGGCCGACCGGGAGCGGCAGGAGG
AGCTGCAGCGCCACCTGGAGGATGCCAACCGCGCGCGCCACGGGTTGGAGACGCAGCACCGGCTGAACCAGCAGCAGCTATCCGAGCTGC
GGGCCCAGGTGGAGGACCTGCAGAAAGCCCTGCAGGAGCAGGGGGGCAAGACTGAAGATGCCATTTCCATTTTGCTGAAAAGGAAGCTGG
AGGAACATTTGCAGAAGCTTCATGAGGCAGATCTGGAGTTGCAGAGGAAGCGGGAGTACATTGAGGAGCTGGAGCCACCCACTGACAGCA
GCACAGCCCGGCGGATCGAGGAGCTGCAGCATAACTTGCAGAAGAAGGACGCGGACTTGCGGGCCATGGAGGAGCGATACCGCCGCTACG
TGGACAAGGCCCGCATGGTCATGCAGACCATGGAACCCAAGCAGCGGCCAGCTGCGGGGGCACCTCCAGAACTCCATTCCCTGAGGACAC
AGCTCCGAGAACGGGATGTCCGCATCCGACACCTGGAGATGGACTTTGAGAAAAGCCGAAGTCAGCGGGAGCAGGAAGAAAAGCTGCTCA
TCAGTGCCTGGTATAATATGGGCATGGCCTTGCAGCAGCGAGCTGGGGAGGAGCGGGCGCCTGCCCATGCCCAGTCATTCCTGGCACAGC
AGCGGCTGGCAACCAATTCTCGCCGTGGACCCTTGGGACGCCTGGCATCTCTGAACCTTCGCCCCACTGACAAGCACTGACAGACCTCAC
AATCAAGCCAGCCTGGGCTCCACCCACCCTGGCTTCCTCCAGCTCACATGGCGCCCAGCACTGGGCTTCAGCCAGGTGCTCGAGAGCTTT
GAGGCCATGATCTCTGCTCTTCCCTCTCCCAGATTGGTGGGGAGGGAGGGCGGGAGGTAGATATAGGCCTGTTCTTTTTAGCAATGTGAT

>60480_60480_4_NSFL1C-HOOK2_NSFL1C_chr20_1447365_ENST00000350991_HOOK2_chr19_12885711_ENST00000397668_length(amino acids)=739AA_BP=34
MAAERQEALREFVAVTGAEEDRARFFLESAGWDLQLQTFHVPSPCASPQDLSSGLAVAYVLNQIDPSWFNEAWLQGISEDPGPNWKLKVS
NLKMVLRSLVEYSQDVLAHPVSEEHLPDVSLIGEFSDPAELGKLLQLVLGCAISCEKKQDHIQRIMTLEESVQHVVMEAIQELMTKDTPD
SLSPETYGNFDSQSRRYYFLSEEAEEGDELQQRCLDLERQLMLLSEEKQSLAQENAGLRERMGRPEGEGTPGLTAKKLLLLQSQLEQLQE
ENFRLESGREDERLRCAELEREVAELQHRNQALTSLAQEAQALKDEMDELRQSSERAGQLEATLTSCRRRLGELRELRRQVRQLEERNAG
HAERTRQLEDELRRAGSLRAQLEAQRRQVQELQGQRQEEAMKAEKWLFECRNLEEKYESVTKEKERLLAERDSLREANEELRCAQLQPRG
LTQADPSLDPTSTPVDNLAAEILPAELRETLLRLQLENKRLCRQEAADRERQEELQRHLEDANRARHGLETQHRLNQQQLSELRAQVEDL
QKALQEQGGKTEDAISILLKRKLEEHLQKLHEADLELQRKREYIEELEPPTDSSTARRIEELQHNLQKKDADLRAMEERYRRYVDKARMV
MQTMEPKQRPAAGAPPELHSLRTQLRERDVRIRHLEMDFEKSRSQREQEEKLLISAWYNMGMALQQRAGEERAPAHAQSFLAQQRLATNS

--------------------------------------------------------------
>60480_60480_5_NSFL1C-HOOK2_NSFL1C_chr20_1447365_ENST00000353088_HOOK2_chr19_12885711_ENST00000264827_length(transcript)=2496nt_BP=109nt
GAAGATGGCGGCGGAGCGACAGGAGGCGCTGAGGGAGTTCGTGGCGGTGACGGGCGCCGAGGAGGACCGGGCCCGCTTCTTTCTCGAGTC
GGCCGGCTGGGACTTGCAGTTACAGACGTTCCACGTTCCGTCTCCCTGTGCCAGCCCTCAGGACCTGAGCAGCGGCCTTGCCGTAGCCTA
TGTGCTGAACCAGATAGACCCCTCCTGGTTCAACGAGGCATGGCTCCAGGGCATCTCGGAAGATCCAGGTCCCAACTGGAAGCTGAAGGT
CAGCAATCTGAAGATGGTCTTACGGAGCCTAGTAGAGTACTCCCAGGATGTCCTGGCGCATCCTGTGTCAGAAGAGCATCTCCCAGATGT
GAGCCTCATTGGAGAGTTCTCAGACCCGGCAGAGCTCGGCAAGCTGCTTCAGCTGGTGCTGGGCTGTGCCATCAGTTGCGAGAAAAAGCA
GGACCACATCCAGAGAATCATGACGCTGGAAGAATCGGTTCAGCATGTGGTGATGGAAGCCATCCAAGAGCTCATGACCAAAGACACTCC
TGACTCCCTGTCACCAGAGACGTATGGCAACTTTGACAGCCAGTCCCGCAGGTACTATTTCCTAAGTGAGGAGGCTGAGGAGGGGGACGA
ATTACAGCAGCGCTGTCTGGATCTGGAGCGGCAGCTGATGCTCCTGTCAGAGGAGAAGCAGAGCCTGGCGCAAGAGAATGCAGGGCTGCG
GGAGCGGATGGGCCGGCCTGAAGGCGAGGGTACCCCAGGTCTCACTGCCAAGAAGCTGCTGCTGCTGCAATCCCAGCTGGAGCAGTTGCA
GGAGGAGAACTTCAGGCTGGAGAGTGGCAGGGAGGATGAGCGCCTGCGCTGTGCCGAGCTGGAGAGGGAGGTTGCGGAGCTGCAGCACCG
GAACCAGGCGCTGACTAGCCTGGCCCAGGAGGCACAGGCCCTGAAGGATGAGATGGATGAACTACGGCAGTCTTCGGAGCGTGCTGGGCA
GCTGGAGGCCACGCTGACCAGTTGCCGGCGCCGCTTGGGCGAGCTGAGGGAGCTGCGGCGGCAGGTGCGGCAGCTGGAGGAACGCAACGC
CGGCCACGCCGAGCGCACGCGACAACTGGAGGATGAGCTACGCCGAGCGGGCTCCCTGCGCGCCCAGCTGGAGGCGCAGCGGCGGCAGGT
GCAGGAACTGCAGGGCCAGCGGCAGGAGGAGGCCATGAAGGCCGAGAAATGGCTATTTGAATGCCGCAACCTGGAGGAAAAGTATGAGTC
GGTGACAAAGGAGAAGGAGCGGCTGTTGGCGGAGCGGGACTCCTTGCGGGAGGCCAATGAGGAGCTGCGCTGCGCCCAGCTGCAGCCGCG
GGGGTTGACCCAGGCCGATCCCTCACTGGATCCCACCTCCACACCCGTGGATAACTTAGCCGCAGAGATCCTGCCTGCGGAGCTCAGGGA
GACGCTCCTGCGGCTTCAGCTGGAGAACAAGCGGCTGTGCAGGCAGGAGGCGGCCGACCGGGAGCGGCAGGAGGAGCTGCAGCGCCACCT
GGAGGATGCCAACCGCGCGCGCCACGGGTTGGAGACGCAGCACCGGCTGAACCAGCAGCAGCTATCCGAGCTGCGGGCCCAGGTGGAGGA
CCTGCAGAAAGCCCTGCAGGAGCAGGGGGGCAAGACTGAAGATTCCATTTTGCTGAAAAGGAAGCTGGAGGAACATTTGCAGAAGCTTCA
TGAGGCAGATCTGGAGTTGCAGAGGAAGCGGGAGTACATTGAGGAGCTGGAGCCACCCACTGACAGCAGCACAGCCCGGCGGATCGAGGA
GCTGCAGCATAACTTGCAGAAGAAGGACGCGGACTTGCGGGCCATGGAGGAGCGATACCGCCGCTACGTGGACAAGGCCCGCATGGTCAT
GCAGACCATGGAACCCAAGCAGCGGCCAGCTGCGGGGGCACCTCCAGAACTCCATTCCCTGAGGACACAGCTCCGAGAACGGGATGTCCG
CATCCGACACCTGGAGATGGACTTTGAGAAAAGCCGAAGTCAGCGGGAGCAGGAAGAAAAGCTGCTCATCAGTGCCTGGTATAATATGGG
CATGGCCTTGCAGCAGCGAGCTGGGGAGGAGCGGGCGCCTGCCCATGCCCAGTCATTCCTGGCACAGCAGCGGCTGGCAACCAATTCTCG
CCGTGGACCCTTGGGACGCCTGGCATCTCTGAACCTTCGCCCCACTGACAAGCACTGACAGACCTCACAATCAAGCCAGCCTGGGCTCCA
CCCACCCTGGCTTCCTCCAGCTCACATGGCGCCCAGCACTGGGCTTCAGCCAGGTGCTCGAGAGCTTTGAGGCCATGATCTCTGCTCTTC
CCTCTCCCAGATTGGTGGGGAGGGAGGGCGGGAGGTAGATATAGGCCTGTTCTTTTTAGCAATGTGATTCTTGTTGTTGATTCTCTCTCT

>60480_60480_5_NSFL1C-HOOK2_NSFL1C_chr20_1447365_ENST00000353088_HOOK2_chr19_12885711_ENST00000264827_length(amino acids)=737AA_BP=34
MAAERQEALREFVAVTGAEEDRARFFLESAGWDLQLQTFHVPSPCASPQDLSSGLAVAYVLNQIDPSWFNEAWLQGISEDPGPNWKLKVS
NLKMVLRSLVEYSQDVLAHPVSEEHLPDVSLIGEFSDPAELGKLLQLVLGCAISCEKKQDHIQRIMTLEESVQHVVMEAIQELMTKDTPD
SLSPETYGNFDSQSRRYYFLSEEAEEGDELQQRCLDLERQLMLLSEEKQSLAQENAGLRERMGRPEGEGTPGLTAKKLLLLQSQLEQLQE
ENFRLESGREDERLRCAELEREVAELQHRNQALTSLAQEAQALKDEMDELRQSSERAGQLEATLTSCRRRLGELRELRRQVRQLEERNAG
HAERTRQLEDELRRAGSLRAQLEAQRRQVQELQGQRQEEAMKAEKWLFECRNLEEKYESVTKEKERLLAERDSLREANEELRCAQLQPRG
LTQADPSLDPTSTPVDNLAAEILPAELRETLLRLQLENKRLCRQEAADRERQEELQRHLEDANRARHGLETQHRLNQQQLSELRAQVEDL
QKALQEQGGKTEDSILLKRKLEEHLQKLHEADLELQRKREYIEELEPPTDSSTARRIEELQHNLQKKDADLRAMEERYRRYVDKARMVMQ
TMEPKQRPAAGAPPELHSLRTQLRERDVRIRHLEMDFEKSRSQREQEEKLLISAWYNMGMALQQRAGEERAPAHAQSFLAQQRLATNSRR

--------------------------------------------------------------
>60480_60480_6_NSFL1C-HOOK2_NSFL1C_chr20_1447365_ENST00000353088_HOOK2_chr19_12885711_ENST00000397668_length(transcript)=2503nt_BP=109nt
GAAGATGGCGGCGGAGCGACAGGAGGCGCTGAGGGAGTTCGTGGCGGTGACGGGCGCCGAGGAGGACCGGGCCCGCTTCTTTCTCGAGTC
GGCCGGCTGGGACTTGCAGTTACAGACGTTCCACGTTCCGTCTCCCTGTGCCAGCCCTCAGGACCTGAGCAGCGGCCTTGCCGTAGCCTA
TGTGCTGAACCAGATAGACCCCTCCTGGTTCAACGAGGCATGGCTCCAGGGCATCTCGGAAGATCCAGGTCCCAACTGGAAGCTGAAGGT
CAGCAATCTGAAGATGGTCTTACGGAGCCTAGTAGAGTACTCCCAGGATGTCCTGGCGCATCCTGTGTCAGAAGAGCATCTCCCAGATGT
GAGCCTCATTGGAGAGTTCTCAGACCCGGCAGAGCTCGGCAAGCTGCTTCAGCTGGTGCTGGGCTGTGCCATCAGTTGCGAGAAAAAGCA
GGACCACATCCAGAGAATCATGACGCTGGAAGAATCGGTTCAGCATGTGGTGATGGAAGCCATCCAAGAGCTCATGACCAAAGACACTCC
TGACTCCCTGTCACCAGAGACGTATGGCAACTTTGACAGCCAGTCCCGCAGGTACTATTTCCTAAGTGAGGAGGCTGAGGAGGGGGACGA
ATTACAGCAGCGCTGTCTGGATCTGGAGCGGCAGCTGATGCTCCTGTCAGAGGAGAAGCAGAGCCTGGCGCAAGAGAATGCAGGGCTGCG
GGAGCGGATGGGCCGGCCTGAAGGCGAGGGTACCCCAGGTCTCACTGCCAAGAAGCTGCTGCTGCTGCAATCCCAGCTGGAGCAGTTGCA
GGAGGAGAACTTCAGGCTGGAGAGTGGCAGGGAGGATGAGCGCCTGCGCTGTGCCGAGCTGGAGAGGGAGGTTGCGGAGCTGCAGCACCG
GAACCAGGCGCTGACTAGCCTGGCCCAGGAGGCACAGGCCCTGAAGGATGAGATGGATGAACTACGGCAGTCTTCGGAGCGTGCTGGGCA
GCTGGAGGCCACGCTGACCAGTTGCCGGCGCCGCTTGGGCGAGCTGAGGGAGCTGCGGCGGCAGGTGCGGCAGCTGGAGGAACGCAACGC
CGGCCACGCCGAGCGCACGCGACAACTGGAGGATGAGCTACGCCGAGCGGGCTCCCTGCGCGCCCAGCTGGAGGCGCAGCGGCGGCAGGT
GCAGGAACTGCAGGGCCAGCGGCAGGAGGAGGCCATGAAGGCCGAGAAATGGCTATTTGAATGCCGCAACCTGGAGGAAAAGTATGAGTC
GGTGACAAAGGAGAAGGAGCGGCTGTTGGCGGAGCGGGACTCCTTGCGGGAGGCCAATGAGGAGCTGCGCTGCGCCCAGCTGCAGCCGCG
GGGGTTGACCCAGGCCGATCCCTCACTGGATCCCACCTCCACACCCGTGGATAACTTAGCCGCAGAGATCCTGCCTGCGGAGCTCAGGGA
GACGCTCCTGCGGCTTCAGCTGGAGAACAAGCGGCTGTGCAGGCAGGAGGCGGCCGACCGGGAGCGGCAGGAGGAGCTGCAGCGCCACCT
GGAGGATGCCAACCGCGCGCGCCACGGGTTGGAGACGCAGCACCGGCTGAACCAGCAGCAGCTATCCGAGCTGCGGGCCCAGGTGGAGGA
CCTGCAGAAAGCCCTGCAGGAGCAGGGGGGCAAGACTGAAGATGCCATTTCCATTTTGCTGAAAAGGAAGCTGGAGGAACATTTGCAGAA
GCTTCATGAGGCAGATCTGGAGTTGCAGAGGAAGCGGGAGTACATTGAGGAGCTGGAGCCACCCACTGACAGCAGCACAGCCCGGCGGAT
CGAGGAGCTGCAGCATAACTTGCAGAAGAAGGACGCGGACTTGCGGGCCATGGAGGAGCGATACCGCCGCTACGTGGACAAGGCCCGCAT
GGTCATGCAGACCATGGAACCCAAGCAGCGGCCAGCTGCGGGGGCACCTCCAGAACTCCATTCCCTGAGGACACAGCTCCGAGAACGGGA
TGTCCGCATCCGACACCTGGAGATGGACTTTGAGAAAAGCCGAAGTCAGCGGGAGCAGGAAGAAAAGCTGCTCATCAGTGCCTGGTATAA
TATGGGCATGGCCTTGCAGCAGCGAGCTGGGGAGGAGCGGGCGCCTGCCCATGCCCAGTCATTCCTGGCACAGCAGCGGCTGGCAACCAA
TTCTCGCCGTGGACCCTTGGGACGCCTGGCATCTCTGAACCTTCGCCCCACTGACAAGCACTGACAGACCTCACAATCAAGCCAGCCTGG
GCTCCACCCACCCTGGCTTCCTCCAGCTCACATGGCGCCCAGCACTGGGCTTCAGCCAGGTGCTCGAGAGCTTTGAGGCCATGATCTCTG
CTCTTCCCTCTCCCAGATTGGTGGGGAGGGAGGGCGGGAGGTAGATATAGGCCTGTTCTTTTTAGCAATGTGATTCTTGTTGTTGATTCT

>60480_60480_6_NSFL1C-HOOK2_NSFL1C_chr20_1447365_ENST00000353088_HOOK2_chr19_12885711_ENST00000397668_length(amino acids)=739AA_BP=34
MAAERQEALREFVAVTGAEEDRARFFLESAGWDLQLQTFHVPSPCASPQDLSSGLAVAYVLNQIDPSWFNEAWLQGISEDPGPNWKLKVS
NLKMVLRSLVEYSQDVLAHPVSEEHLPDVSLIGEFSDPAELGKLLQLVLGCAISCEKKQDHIQRIMTLEESVQHVVMEAIQELMTKDTPD
SLSPETYGNFDSQSRRYYFLSEEAEEGDELQQRCLDLERQLMLLSEEKQSLAQENAGLRERMGRPEGEGTPGLTAKKLLLLQSQLEQLQE
ENFRLESGREDERLRCAELEREVAELQHRNQALTSLAQEAQALKDEMDELRQSSERAGQLEATLTSCRRRLGELRELRRQVRQLEERNAG
HAERTRQLEDELRRAGSLRAQLEAQRRQVQELQGQRQEEAMKAEKWLFECRNLEEKYESVTKEKERLLAERDSLREANEELRCAQLQPRG
LTQADPSLDPTSTPVDNLAAEILPAELRETLLRLQLENKRLCRQEAADRERQEELQRHLEDANRARHGLETQHRLNQQQLSELRAQVEDL
QKALQEQGGKTEDAISILLKRKLEEHLQKLHEADLELQRKREYIEELEPPTDSSTARRIEELQHNLQKKDADLRAMEERYRRYVDKARMV
MQTMEPKQRPAAGAPPELHSLRTQLRERDVRIRHLEMDFEKSRSQREQEEKLLISAWYNMGMALQQRAGEERAPAHAQSFLAQQRLATNS

--------------------------------------------------------------
>60480_60480_7_NSFL1C-HOOK2_NSFL1C_chr20_1447365_ENST00000476071_HOOK2_chr19_12885711_ENST00000264827_length(transcript)=2586nt_BP=199nt
GGCTGGGCCTCGTCGACCGGCAAGCGGAACGCGGCAGCGGGGCTGGGCCTGTGCGGCGGCCGCCGGAGCGCTTTGGAAGGCGCACGGGGC
GAAGATGGCGGCGGAGCGACAGGAGGCGCTGAGGGAGTTCGTGGCGGTGACGGGCGCCGAGGAGGACCGGGCCCGCTTCTTTCTCGAGTC
GGCCGGCTGGGACTTGCAGTTACAGACGTTCCACGTTCCGTCTCCCTGTGCCAGCCCTCAGGACCTGAGCAGCGGCCTTGCCGTAGCCTA
TGTGCTGAACCAGATAGACCCCTCCTGGTTCAACGAGGCATGGCTCCAGGGCATCTCGGAAGATCCAGGTCCCAACTGGAAGCTGAAGGT
CAGCAATCTGAAGATGGTCTTACGGAGCCTAGTAGAGTACTCCCAGGATGTCCTGGCGCATCCTGTGTCAGAAGAGCATCTCCCAGATGT
GAGCCTCATTGGAGAGTTCTCAGACCCGGCAGAGCTCGGCAAGCTGCTTCAGCTGGTGCTGGGCTGTGCCATCAGTTGCGAGAAAAAGCA
GGACCACATCCAGAGAATCATGACGCTGGAAGAATCGGTTCAGCATGTGGTGATGGAAGCCATCCAAGAGCTCATGACCAAAGACACTCC
TGACTCCCTGTCACCAGAGACGTATGGCAACTTTGACAGCCAGTCCCGCAGGTACTATTTCCTAAGTGAGGAGGCTGAGGAGGGGGACGA
ATTACAGCAGCGCTGTCTGGATCTGGAGCGGCAGCTGATGCTCCTGTCAGAGGAGAAGCAGAGCCTGGCGCAAGAGAATGCAGGGCTGCG
GGAGCGGATGGGCCGGCCTGAAGGCGAGGGTACCCCAGGTCTCACTGCCAAGAAGCTGCTGCTGCTGCAATCCCAGCTGGAGCAGTTGCA
GGAGGAGAACTTCAGGCTGGAGAGTGGCAGGGAGGATGAGCGCCTGCGCTGTGCCGAGCTGGAGAGGGAGGTTGCGGAGCTGCAGCACCG
GAACCAGGCGCTGACTAGCCTGGCCCAGGAGGCACAGGCCCTGAAGGATGAGATGGATGAACTACGGCAGTCTTCGGAGCGTGCTGGGCA
GCTGGAGGCCACGCTGACCAGTTGCCGGCGCCGCTTGGGCGAGCTGAGGGAGCTGCGGCGGCAGGTGCGGCAGCTGGAGGAACGCAACGC
CGGCCACGCCGAGCGCACGCGACAACTGGAGGATGAGCTACGCCGAGCGGGCTCCCTGCGCGCCCAGCTGGAGGCGCAGCGGCGGCAGGT
GCAGGAACTGCAGGGCCAGCGGCAGGAGGAGGCCATGAAGGCCGAGAAATGGCTATTTGAATGCCGCAACCTGGAGGAAAAGTATGAGTC
GGTGACAAAGGAGAAGGAGCGGCTGTTGGCGGAGCGGGACTCCTTGCGGGAGGCCAATGAGGAGCTGCGCTGCGCCCAGCTGCAGCCGCG
GGGGTTGACCCAGGCCGATCCCTCACTGGATCCCACCTCCACACCCGTGGATAACTTAGCCGCAGAGATCCTGCCTGCGGAGCTCAGGGA
GACGCTCCTGCGGCTTCAGCTGGAGAACAAGCGGCTGTGCAGGCAGGAGGCGGCCGACCGGGAGCGGCAGGAGGAGCTGCAGCGCCACCT
GGAGGATGCCAACCGCGCGCGCCACGGGTTGGAGACGCAGCACCGGCTGAACCAGCAGCAGCTATCCGAGCTGCGGGCCCAGGTGGAGGA
CCTGCAGAAAGCCCTGCAGGAGCAGGGGGGCAAGACTGAAGATTCCATTTTGCTGAAAAGGAAGCTGGAGGAACATTTGCAGAAGCTTCA
TGAGGCAGATCTGGAGTTGCAGAGGAAGCGGGAGTACATTGAGGAGCTGGAGCCACCCACTGACAGCAGCACAGCCCGGCGGATCGAGGA
GCTGCAGCATAACTTGCAGAAGAAGGACGCGGACTTGCGGGCCATGGAGGAGCGATACCGCCGCTACGTGGACAAGGCCCGCATGGTCAT
GCAGACCATGGAACCCAAGCAGCGGCCAGCTGCGGGGGCACCTCCAGAACTCCATTCCCTGAGGACACAGCTCCGAGAACGGGATGTCCG
CATCCGACACCTGGAGATGGACTTTGAGAAAAGCCGAAGTCAGCGGGAGCAGGAAGAAAAGCTGCTCATCAGTGCCTGGTATAATATGGG
CATGGCCTTGCAGCAGCGAGCTGGGGAGGAGCGGGCGCCTGCCCATGCCCAGTCATTCCTGGCACAGCAGCGGCTGGCAACCAATTCTCG
CCGTGGACCCTTGGGACGCCTGGCATCTCTGAACCTTCGCCCCACTGACAAGCACTGACAGACCTCACAATCAAGCCAGCCTGGGCTCCA
CCCACCCTGGCTTCCTCCAGCTCACATGGCGCCCAGCACTGGGCTTCAGCCAGGTGCTCGAGAGCTTTGAGGCCATGATCTCTGCTCTTC
CCTCTCCCAGATTGGTGGGGAGGGAGGGCGGGAGGTAGATATAGGCCTGTTCTTTTTAGCAATGTGATTCTTGTTGTTGATTCTCTCTCT

>60480_60480_7_NSFL1C-HOOK2_NSFL1C_chr20_1447365_ENST00000476071_HOOK2_chr19_12885711_ENST00000264827_length(amino acids)=737AA_BP=34
MAAERQEALREFVAVTGAEEDRARFFLESAGWDLQLQTFHVPSPCASPQDLSSGLAVAYVLNQIDPSWFNEAWLQGISEDPGPNWKLKVS
NLKMVLRSLVEYSQDVLAHPVSEEHLPDVSLIGEFSDPAELGKLLQLVLGCAISCEKKQDHIQRIMTLEESVQHVVMEAIQELMTKDTPD
SLSPETYGNFDSQSRRYYFLSEEAEEGDELQQRCLDLERQLMLLSEEKQSLAQENAGLRERMGRPEGEGTPGLTAKKLLLLQSQLEQLQE
ENFRLESGREDERLRCAELEREVAELQHRNQALTSLAQEAQALKDEMDELRQSSERAGQLEATLTSCRRRLGELRELRRQVRQLEERNAG
HAERTRQLEDELRRAGSLRAQLEAQRRQVQELQGQRQEEAMKAEKWLFECRNLEEKYESVTKEKERLLAERDSLREANEELRCAQLQPRG
LTQADPSLDPTSTPVDNLAAEILPAELRETLLRLQLENKRLCRQEAADRERQEELQRHLEDANRARHGLETQHRLNQQQLSELRAQVEDL
QKALQEQGGKTEDSILLKRKLEEHLQKLHEADLELQRKREYIEELEPPTDSSTARRIEELQHNLQKKDADLRAMEERYRRYVDKARMVMQ
TMEPKQRPAAGAPPELHSLRTQLRERDVRIRHLEMDFEKSRSQREQEEKLLISAWYNMGMALQQRAGEERAPAHAQSFLAQQRLATNSRR

--------------------------------------------------------------
>60480_60480_8_NSFL1C-HOOK2_NSFL1C_chr20_1447365_ENST00000476071_HOOK2_chr19_12885711_ENST00000397668_length(transcript)=2593nt_BP=199nt
GGCTGGGCCTCGTCGACCGGCAAGCGGAACGCGGCAGCGGGGCTGGGCCTGTGCGGCGGCCGCCGGAGCGCTTTGGAAGGCGCACGGGGC
GAAGATGGCGGCGGAGCGACAGGAGGCGCTGAGGGAGTTCGTGGCGGTGACGGGCGCCGAGGAGGACCGGGCCCGCTTCTTTCTCGAGTC
GGCCGGCTGGGACTTGCAGTTACAGACGTTCCACGTTCCGTCTCCCTGTGCCAGCCCTCAGGACCTGAGCAGCGGCCTTGCCGTAGCCTA
TGTGCTGAACCAGATAGACCCCTCCTGGTTCAACGAGGCATGGCTCCAGGGCATCTCGGAAGATCCAGGTCCCAACTGGAAGCTGAAGGT
CAGCAATCTGAAGATGGTCTTACGGAGCCTAGTAGAGTACTCCCAGGATGTCCTGGCGCATCCTGTGTCAGAAGAGCATCTCCCAGATGT
GAGCCTCATTGGAGAGTTCTCAGACCCGGCAGAGCTCGGCAAGCTGCTTCAGCTGGTGCTGGGCTGTGCCATCAGTTGCGAGAAAAAGCA
GGACCACATCCAGAGAATCATGACGCTGGAAGAATCGGTTCAGCATGTGGTGATGGAAGCCATCCAAGAGCTCATGACCAAAGACACTCC
TGACTCCCTGTCACCAGAGACGTATGGCAACTTTGACAGCCAGTCCCGCAGGTACTATTTCCTAAGTGAGGAGGCTGAGGAGGGGGACGA
ATTACAGCAGCGCTGTCTGGATCTGGAGCGGCAGCTGATGCTCCTGTCAGAGGAGAAGCAGAGCCTGGCGCAAGAGAATGCAGGGCTGCG
GGAGCGGATGGGCCGGCCTGAAGGCGAGGGTACCCCAGGTCTCACTGCCAAGAAGCTGCTGCTGCTGCAATCCCAGCTGGAGCAGTTGCA
GGAGGAGAACTTCAGGCTGGAGAGTGGCAGGGAGGATGAGCGCCTGCGCTGTGCCGAGCTGGAGAGGGAGGTTGCGGAGCTGCAGCACCG
GAACCAGGCGCTGACTAGCCTGGCCCAGGAGGCACAGGCCCTGAAGGATGAGATGGATGAACTACGGCAGTCTTCGGAGCGTGCTGGGCA
GCTGGAGGCCACGCTGACCAGTTGCCGGCGCCGCTTGGGCGAGCTGAGGGAGCTGCGGCGGCAGGTGCGGCAGCTGGAGGAACGCAACGC
CGGCCACGCCGAGCGCACGCGACAACTGGAGGATGAGCTACGCCGAGCGGGCTCCCTGCGCGCCCAGCTGGAGGCGCAGCGGCGGCAGGT
GCAGGAACTGCAGGGCCAGCGGCAGGAGGAGGCCATGAAGGCCGAGAAATGGCTATTTGAATGCCGCAACCTGGAGGAAAAGTATGAGTC
GGTGACAAAGGAGAAGGAGCGGCTGTTGGCGGAGCGGGACTCCTTGCGGGAGGCCAATGAGGAGCTGCGCTGCGCCCAGCTGCAGCCGCG
GGGGTTGACCCAGGCCGATCCCTCACTGGATCCCACCTCCACACCCGTGGATAACTTAGCCGCAGAGATCCTGCCTGCGGAGCTCAGGGA
GACGCTCCTGCGGCTTCAGCTGGAGAACAAGCGGCTGTGCAGGCAGGAGGCGGCCGACCGGGAGCGGCAGGAGGAGCTGCAGCGCCACCT
GGAGGATGCCAACCGCGCGCGCCACGGGTTGGAGACGCAGCACCGGCTGAACCAGCAGCAGCTATCCGAGCTGCGGGCCCAGGTGGAGGA
CCTGCAGAAAGCCCTGCAGGAGCAGGGGGGCAAGACTGAAGATGCCATTTCCATTTTGCTGAAAAGGAAGCTGGAGGAACATTTGCAGAA
GCTTCATGAGGCAGATCTGGAGTTGCAGAGGAAGCGGGAGTACATTGAGGAGCTGGAGCCACCCACTGACAGCAGCACAGCCCGGCGGAT
CGAGGAGCTGCAGCATAACTTGCAGAAGAAGGACGCGGACTTGCGGGCCATGGAGGAGCGATACCGCCGCTACGTGGACAAGGCCCGCAT
GGTCATGCAGACCATGGAACCCAAGCAGCGGCCAGCTGCGGGGGCACCTCCAGAACTCCATTCCCTGAGGACACAGCTCCGAGAACGGGA
TGTCCGCATCCGACACCTGGAGATGGACTTTGAGAAAAGCCGAAGTCAGCGGGAGCAGGAAGAAAAGCTGCTCATCAGTGCCTGGTATAA
TATGGGCATGGCCTTGCAGCAGCGAGCTGGGGAGGAGCGGGCGCCTGCCCATGCCCAGTCATTCCTGGCACAGCAGCGGCTGGCAACCAA
TTCTCGCCGTGGACCCTTGGGACGCCTGGCATCTCTGAACCTTCGCCCCACTGACAAGCACTGACAGACCTCACAATCAAGCCAGCCTGG
GCTCCACCCACCCTGGCTTCCTCCAGCTCACATGGCGCCCAGCACTGGGCTTCAGCCAGGTGCTCGAGAGCTTTGAGGCCATGATCTCTG
CTCTTCCCTCTCCCAGATTGGTGGGGAGGGAGGGCGGGAGGTAGATATAGGCCTGTTCTTTTTAGCAATGTGATTCTTGTTGTTGATTCT

>60480_60480_8_NSFL1C-HOOK2_NSFL1C_chr20_1447365_ENST00000476071_HOOK2_chr19_12885711_ENST00000397668_length(amino acids)=739AA_BP=34
MAAERQEALREFVAVTGAEEDRARFFLESAGWDLQLQTFHVPSPCASPQDLSSGLAVAYVLNQIDPSWFNEAWLQGISEDPGPNWKLKVS
NLKMVLRSLVEYSQDVLAHPVSEEHLPDVSLIGEFSDPAELGKLLQLVLGCAISCEKKQDHIQRIMTLEESVQHVVMEAIQELMTKDTPD
SLSPETYGNFDSQSRRYYFLSEEAEEGDELQQRCLDLERQLMLLSEEKQSLAQENAGLRERMGRPEGEGTPGLTAKKLLLLQSQLEQLQE
ENFRLESGREDERLRCAELEREVAELQHRNQALTSLAQEAQALKDEMDELRQSSERAGQLEATLTSCRRRLGELRELRRQVRQLEERNAG
HAERTRQLEDELRRAGSLRAQLEAQRRQVQELQGQRQEEAMKAEKWLFECRNLEEKYESVTKEKERLLAERDSLREANEELRCAQLQPRG
LTQADPSLDPTSTPVDNLAAEILPAELRETLLRLQLENKRLCRQEAADRERQEELQRHLEDANRARHGLETQHRLNQQQLSELRAQVEDL
QKALQEQGGKTEDAISILLKRKLEEHLQKLHEADLELQRKREYIEELEPPTDSSTARRIEELQHNLQKKDADLRAMEERYRRYVDKARMV
MQTMEPKQRPAAGAPPELHSLRTQLRERDVRIRHLEMDFEKSRSQREQEEKLLISAWYNMGMALQQRAGEERAPAHAQSFLAQQRLATNS

--------------------------------------------------------------

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Fusion Gene PPI Analysis for NSFL1C-HOOK2


check button Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in

ChiPPI page.


check button Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160)
HgeneHgene's interactorsTgeneTgene's interactors


check button - Retained PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenStill interaction with


check button - Lost PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


check button - Retained PPIs, but lost function due to frame-shift fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


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Related Drugs for NSFL1C-HOOK2


check button Drugs targeting genes involved in this fusion gene.
(DrugBank Version 5.1.8 2021-05-08)
PartnerGeneUniProtAccDrugBank IDDrug nameDrug activityDrug typeDrug status

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Related Diseases for NSFL1C-HOOK2


check button Diseases associated with fusion partners.
(DisGeNet 4.0)
PartnerGeneDisease IDDisease name# pubmedsSource