FusionGDB Logo

Home

Download

Statistics

Examples

Help

Contact
Center for Computational Systems Medicine
leaf

Fusion Gene Summary

leaf

Fusion Gene ORF analysis

leaf

Fusion Genomic Features

leaf

Fusion Protein Features

leaf

Fusion Gene Sequence

leaf

Fusion Gene PPI analysis

leaf

Related Drugs

leaf

Related Diseases

Fusion gene:NUCB1-RUVBL2 (FusionGDB2 ID:60762)

Fusion Gene Summary for NUCB1-RUVBL2

check button Fusion gene summary
Fusion gene informationFusion gene name: NUCB1-RUVBL2
Fusion gene ID: 60762
HgeneTgene
Gene symbol

NUCB1

RUVBL2

Gene ID

4924

10856

Gene namenucleobindin 1RuvB like AAA ATPase 2
SynonymsCALNUC|NUCCGI-46|ECP-51|ECP51|INO80J|REPTIN|RVB2|TAP54-beta|TIH2|TIP48|TIP49B
Cytomap

19q13.33

19q13.33

Type of geneprotein-codingprotein-coding
Descriptionnucleobindin-1ruvB-like 248 kDa TATA box-binding protein-interacting protein48 kDa TBP-interacting protein51 kDa erythrocyte cytosolic proteinINO80 complex subunit JRuvB (E coli homolog)-like 2TIP60-associated protein 54-betaerythrocyte cytosolic protein, 51-KD
Modification date2020031320200327
UniProtAcc..
Ensembl transtripts involved in fusion geneENST00000263273, ENST00000405315, 
ENST00000407032, ENST00000485798, 
ENST00000413176, ENST00000598768, 
ENST00000595090, ENST00000601968, 
Fusion gene scores* DoF score9 X 11 X 6=5946 X 7 X 6=252
# samples 147
** MAII scorelog2(14/594*10)=-2.0850361038558
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0		log2(7/252*10)=-1.84799690655495
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0
Context

PubMed: NUCB1 [Title/Abstract] AND RUVBL2 [Title/Abstract] AND fusion [Title/Abstract]

Most frequent breakpointNUCB1(49407711)-RUVBL2(49513033), # samples:3
RUVBL2(49502630)-NUCB1(49407604), # samples:1
Anticipated loss of major functional domain due to fusion event.RUVBL2-NUCB1 seems lost the major protein functional domain in Hgene partner, which is a epigenetic factor due to the frame-shifted ORF.
RUVBL2-NUCB1 seems lost the major protein functional domain in Hgene partner, which is a essential gene due to the frame-shifted ORF.
RUVBL2-NUCB1 seems lost the major protein functional domain in Tgene partner, which is a IUPHAR drug target due to the frame-shifted ORF.
* DoF score (Degree of Frequency) = # partners X # break points X # cancer types
** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)

check button Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez
PartnerGeneGO IDGO termPubMed ID
TgeneRUVBL2

GO:0043967

histone H4 acetylation

14966270

TgeneRUVBL2

GO:0043968

histone H2A acetylation

14966270

TgeneRUVBL2

GO:0090090

negative regulation of canonical Wnt signaling pathway

11080158


check buttonFusion gene breakpoints across NUCB1 (5'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check buttonFusion gene breakpoints across RUVBL2 (3'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check button Fusion gene information from two resources (ChiTars 5.0 and ChimerDB 4.0)
* All genome coordinats were lifted-over on hg19.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
SourceDiseaseSampleHgeneHchrHbpHstrandTgeneTchrTbpTstrand
ChimerDB4LAMLTCGA-AB-2935-03ANUCB1chr19

49407711

+RUVBL2chr19

49513033

+
ChimerDB4LAMLTCGA-AB-2935_61FFWAAXX_1NUCB1chr19

49407711

+RUVBL2chr19

49513033

+
ChimerDB4LAMLTCGA-AB-2935_704G6AAXX_1NUCB1chr19

49407711

+RUVBL2chr19

49513033

+
ChimerDB4LAMLTCGA-AB-2935NUCB1chr19

49407711

+RUVBL2chr19

49513032

+


Top

Fusion Gene ORF analysis for NUCB1-RUVBL2

check button Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
ORFHenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrand
5CDS-intronENST00000263273ENST00000413176NUCB1chr19

49407711

+RUVBL2chr19

49513033

+
5CDS-intronENST00000263273ENST00000413176NUCB1chr19

49407711

+RUVBL2chr19

49513032

+
5CDS-intronENST00000263273ENST00000598768NUCB1chr19

49407711

+RUVBL2chr19

49513033

+
5CDS-intronENST00000263273ENST00000598768NUCB1chr19

49407711

+RUVBL2chr19

49513032

+
5CDS-intronENST00000405315ENST00000413176NUCB1chr19

49407711

+RUVBL2chr19

49513033

+
5CDS-intronENST00000405315ENST00000413176NUCB1chr19

49407711

+RUVBL2chr19

49513032

+
5CDS-intronENST00000405315ENST00000598768NUCB1chr19

49407711

+RUVBL2chr19

49513033

+
5CDS-intronENST00000405315ENST00000598768NUCB1chr19

49407711

+RUVBL2chr19

49513032

+
5CDS-intronENST00000407032ENST00000413176NUCB1chr19

49407711

+RUVBL2chr19

49513033

+
5CDS-intronENST00000407032ENST00000413176NUCB1chr19

49407711

+RUVBL2chr19

49513032

+
5CDS-intronENST00000407032ENST00000598768NUCB1chr19

49407711

+RUVBL2chr19

49513033

+
5CDS-intronENST00000407032ENST00000598768NUCB1chr19

49407711

+RUVBL2chr19

49513032

+
In-frameENST00000263273ENST00000595090NUCB1chr19

49407711

+RUVBL2chr19

49513033

+
In-frameENST00000263273ENST00000595090NUCB1chr19

49407711

+RUVBL2chr19

49513032

+
In-frameENST00000263273ENST00000601968NUCB1chr19

49407711

+RUVBL2chr19

49513033

+
In-frameENST00000263273ENST00000601968NUCB1chr19

49407711

+RUVBL2chr19

49513032

+
In-frameENST00000405315ENST00000595090NUCB1chr19

49407711

+RUVBL2chr19

49513033

+
In-frameENST00000405315ENST00000595090NUCB1chr19

49407711

+RUVBL2chr19

49513032

+
In-frameENST00000405315ENST00000601968NUCB1chr19

49407711

+RUVBL2chr19

49513033

+
In-frameENST00000405315ENST00000601968NUCB1chr19

49407711

+RUVBL2chr19

49513032

+
In-frameENST00000407032ENST00000595090NUCB1chr19

49407711

+RUVBL2chr19

49513033

+
In-frameENST00000407032ENST00000595090NUCB1chr19

49407711

+RUVBL2chr19

49513032

+
In-frameENST00000407032ENST00000601968NUCB1chr19

49407711

+RUVBL2chr19

49513033

+
In-frameENST00000407032ENST00000601968NUCB1chr19

49407711

+RUVBL2chr19

49513032

+
intron-3CDSENST00000485798ENST00000595090NUCB1chr19

49407711

+RUVBL2chr19

49513033

+
intron-3CDSENST00000485798ENST00000595090NUCB1chr19

49407711

+RUVBL2chr19

49513032

+
intron-3CDSENST00000485798ENST00000601968NUCB1chr19

49407711

+RUVBL2chr19

49513033

+
intron-3CDSENST00000485798ENST00000601968NUCB1chr19

49407711

+RUVBL2chr19

49513032

+
intron-intronENST00000485798ENST00000413176NUCB1chr19

49407711

+RUVBL2chr19

49513033

+
intron-intronENST00000485798ENST00000413176NUCB1chr19

49407711

+RUVBL2chr19

49513032

+
intron-intronENST00000485798ENST00000598768NUCB1chr19

49407711

+RUVBL2chr19

49513033

+
intron-intronENST00000485798ENST00000598768NUCB1chr19

49407711

+RUVBL2chr19

49513032

+

check buttonORFfinder result based on the fusion transcript sequence of in-frame fusion genes.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandSeq length
(transcript)		BP loci
(transcript)		Predicted start
(transcript)		Predicted stop
(transcript)		Seq length
(amino acids)
ENST00000405315NUCB1chr1949407711+ENST00000595090RUVBL2chr1949513033+16605773341506390
ENST00000405315NUCB1chr1949407711+ENST00000601968RUVBL2chr1949513033+14275773341314326
ENST00000407032NUCB1chr1949407711+ENST00000595090RUVBL2chr1949513033+1390307641236390
ENST00000407032NUCB1chr1949407711+ENST00000601968RUVBL2chr1949513033+1157307641044326
ENST00000263273NUCB1chr1949407711+ENST00000595090RUVBL2chr1949513033+1339256131185390
ENST00000263273NUCB1chr1949407711+ENST00000601968RUVBL2chr1949513033+110625613993326
ENST00000405315NUCB1chr1949407711+ENST00000595090RUVBL2chr1949513032+16605773341506390
ENST00000405315NUCB1chr1949407711+ENST00000601968RUVBL2chr1949513032+14275773341314326
ENST00000407032NUCB1chr1949407711+ENST00000595090RUVBL2chr1949513032+1390307641236390
ENST00000407032NUCB1chr1949407711+ENST00000601968RUVBL2chr1949513032+1157307641044326
ENST00000263273NUCB1chr1949407711+ENST00000595090RUVBL2chr1949513032+1339256131185390
ENST00000263273NUCB1chr1949407711+ENST00000601968RUVBL2chr1949513032+110625613993326

check buttonDeepORF prediction of the coding potential based on the fusion transcript sequence of in-frame fusion genes. DeepORF is a coding potential classifier based on convolutional neural network by comparing the real Ribo-seq data. If the no-coding score < 0.5 and coding score > 0.5, then the in-frame fusion transcript is predicted as being likely translated.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandNo-coding scoreCoding score
ENST00000405315ENST00000595090NUCB1chr1949407711+RUVBL2chr1949513033+0.0034631870.99653685
ENST00000405315ENST00000601968NUCB1chr1949407711+RUVBL2chr1949513033+0.0065843390.9934156
ENST00000407032ENST00000595090NUCB1chr1949407711+RUVBL2chr1949513033+0.0038099830.99618995
ENST00000407032ENST00000601968NUCB1chr1949407711+RUVBL2chr1949513033+0.0072743180.9927256
ENST00000263273ENST00000595090NUCB1chr1949407711+RUVBL2chr1949513033+0.0040502270.99594975
ENST00000263273ENST00000601968NUCB1chr1949407711+RUVBL2chr1949513033+0.0078830030.992117
ENST00000405315ENST00000595090NUCB1chr1949407711+RUVBL2chr1949513032+0.0034631870.99653685
ENST00000405315ENST00000601968NUCB1chr1949407711+RUVBL2chr1949513032+0.0065843390.9934156
ENST00000407032ENST00000595090NUCB1chr1949407711+RUVBL2chr1949513032+0.0038099830.99618995
ENST00000407032ENST00000601968NUCB1chr1949407711+RUVBL2chr1949513032+0.0072743180.9927256
ENST00000263273ENST00000595090NUCB1chr1949407711+RUVBL2chr1949513032+0.0040502270.99594975
ENST00000263273ENST00000601968NUCB1chr1949407711+RUVBL2chr1949513032+0.0078830030.992117

Top

Fusion Genomic Features for NUCB1-RUVBL2


check buttonFusionAI prediction of the potential fusion gene breakpoint based on the pre-mature RNA sequence context (+/- 5kb of individual partner genes, total 20kb length sequence). FusionAI is a fusion gene breakpoint classifier based on convolutional neural network by comparing the fusion positive and negative sequence context of ~ 20K fusion gene data. From here, we can have the relative potentency of the 20K genomic sequence how individual sequnce will be likely used as the gene fusion breakpoints.
HgeneHchrHbpHstrandTgeneTchrTbpTstrand1-pp (fusion gene breakpoint)
NUCB1chr1949407711+RUVBL2chr1949513032+1.36E-161
NUCB1chr1949407711+RUVBL2chr1949513032+1.36E-161
NUCB1chr1949407711+RUVBL2chr1949513032+1.36E-161
NUCB1chr1949407711+RUVBL2chr1949513032+1.36E-161
NUCB1chr1949407711+RUVBL2chr1949513032+1.36E-161
NUCB1chr1949407711+RUVBL2chr1949513032+1.36E-161

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions. We integrated a total of 44 different types of human genomic feature loci information across five big categories including virus integration sites, repeats, structural variants, chromatin states, and gene expression regulation. More details are in help page.
genomic feature

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions that are ovelapped with the top 1% feature importance score regions. More details are in help page.
genomic feature of top 1%

Top

Fusion Protein Features for NUCB1-RUVBL2


check button Four levels of functional features of fusion genes
Go to FGviewer search page for the most frequent breakpoint (https://ccsmweb.uth.edu/FGviewer/chr19:49407711/chr19:49513033)
- FGviewer provides the online visualization of the retention search of the protein functional features across DNA, RNA, protein, and pathological levels.
- How to search
1. Put your fusion gene symbol.
2. Press the tab key until there will be shown the breakpoint information filled.
4. Go down and press 'Search' tab twice.
4. Go down to have the hyperlink of the search result.
5. Click the hyperlink.
6. See the FGviewer result for your fusion gene.
FGviewer

check buttonMain function of each fusion partner protein. (from UniProt)
HgeneTgene
..
FUNCTION: Transcriptional activator which is required for calcium-dependent dendritic growth and branching in cortical neurons. Recruits CREB-binding protein (CREBBP) to nuclear bodies. Component of the CREST-BRG1 complex, a multiprotein complex that regulates promoter activation by orchestrating a calcium-dependent release of a repressor complex and a recruitment of an activator complex. In resting neurons, transcription of the c-FOS promoter is inhibited by BRG1-dependent recruitment of a phospho-RB1-HDAC1 repressor complex. Upon calcium influx, RB1 is dephosphorylated by calcineurin, which leads to release of the repressor complex. At the same time, there is increased recruitment of CREBBP to the promoter by a CREST-dependent mechanism, which leads to transcriptional activation. The CREST-BRG1 complex also binds to the NR2B promoter, and activity-dependent induction of NR2B expression involves a release of HDAC1 and recruitment of CREBBP (By similarity). {ECO:0000250}.FUNCTION: Transcriptional activator which is required for calcium-dependent dendritic growth and branching in cortical neurons. Recruits CREB-binding protein (CREBBP) to nuclear bodies. Component of the CREST-BRG1 complex, a multiprotein complex that regulates promoter activation by orchestrating a calcium-dependent release of a repressor complex and a recruitment of an activator complex. In resting neurons, transcription of the c-FOS promoter is inhibited by BRG1-dependent recruitment of a phospho-RB1-HDAC1 repressor complex. Upon calcium influx, RB1 is dephosphorylated by calcineurin, which leads to release of the repressor complex. At the same time, there is increased recruitment of CREBBP to the promoter by a CREST-dependent mechanism, which leads to transcriptional activation. The CREST-BRG1 complex also binds to the NR2B promoter, and activity-dependent induction of NR2B expression involves a release of HDAC1 and recruitment of CREBBP (By similarity). {ECO:0000250}.

check buttonRetention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at

download page


* Minus value of BPloci means that the break pointn is located before the CDS.
- In-frame and retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneNUCB1chr19:49407711chr19:49513032ENST00000263273+21242_5181462.0RegionNote=O-glycosylated at one site
HgeneNUCB1chr19:49407711chr19:49513032ENST00000405315+31342_5181462.0RegionNote=O-glycosylated at one site
HgeneNUCB1chr19:49407711chr19:49513032ENST00000407032+31442_5181666.6666666666666RegionNote=O-glycosylated at one site
HgeneNUCB1chr19:49407711chr19:49513033ENST00000263273+21242_5181462.0RegionNote=O-glycosylated at one site
HgeneNUCB1chr19:49407711chr19:49513033ENST00000405315+31342_5181462.0RegionNote=O-glycosylated at one site
HgeneNUCB1chr19:49407711chr19:49513033ENST00000407032+31442_5181666.6666666666666RegionNote=O-glycosylated at one site

- In-frame and not-retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneNUCB1chr19:49407711chr19:49513032ENST00000263273+212253_26481462.0Calcium binding1
HgeneNUCB1chr19:49407711chr19:49513032ENST00000263273+212305_31681462.0Calcium binding2
HgeneNUCB1chr19:49407711chr19:49513032ENST00000405315+313253_26481462.0Calcium binding1
HgeneNUCB1chr19:49407711chr19:49513032ENST00000405315+313305_31681462.0Calcium binding2
HgeneNUCB1chr19:49407711chr19:49513032ENST00000407032+314253_26481666.6666666666666Calcium binding1
HgeneNUCB1chr19:49407711chr19:49513032ENST00000407032+314305_31681666.6666666666666Calcium binding2
HgeneNUCB1chr19:49407711chr19:49513033ENST00000263273+212253_26481462.0Calcium binding1
HgeneNUCB1chr19:49407711chr19:49513033ENST00000263273+212305_31681462.0Calcium binding2
HgeneNUCB1chr19:49407711chr19:49513033ENST00000405315+313253_26481462.0Calcium binding1
HgeneNUCB1chr19:49407711chr19:49513033ENST00000405315+313305_31681462.0Calcium binding2
HgeneNUCB1chr19:49407711chr19:49513033ENST00000407032+314253_26481666.6666666666666Calcium binding1
HgeneNUCB1chr19:49407711chr19:49513033ENST00000407032+314305_31681666.6666666666666Calcium binding2
HgeneNUCB1chr19:49407711chr19:49513032ENST00000263273+212150_21881462.0Coiled coilOntology_term=ECO:0000255
HgeneNUCB1chr19:49407711chr19:49513032ENST00000263273+212341_40781462.0Coiled coilOntology_term=ECO:0000255
HgeneNUCB1chr19:49407711chr19:49513032ENST00000405315+313150_21881462.0Coiled coilOntology_term=ECO:0000255
HgeneNUCB1chr19:49407711chr19:49513032ENST00000405315+313341_40781462.0Coiled coilOntology_term=ECO:0000255
HgeneNUCB1chr19:49407711chr19:49513032ENST00000407032+314150_21881666.6666666666666Coiled coilOntology_term=ECO:0000255
HgeneNUCB1chr19:49407711chr19:49513032ENST00000407032+314341_40781666.6666666666666Coiled coilOntology_term=ECO:0000255
HgeneNUCB1chr19:49407711chr19:49513033ENST00000263273+212150_21881462.0Coiled coilOntology_term=ECO:0000255
HgeneNUCB1chr19:49407711chr19:49513033ENST00000263273+212341_40781462.0Coiled coilOntology_term=ECO:0000255
HgeneNUCB1chr19:49407711chr19:49513033ENST00000405315+313150_21881462.0Coiled coilOntology_term=ECO:0000255
HgeneNUCB1chr19:49407711chr19:49513033ENST00000405315+313341_40781462.0Coiled coilOntology_term=ECO:0000255
HgeneNUCB1chr19:49407711chr19:49513033ENST00000407032+314150_21881666.6666666666666Coiled coilOntology_term=ECO:0000255
HgeneNUCB1chr19:49407711chr19:49513033ENST00000407032+314341_40781666.6666666666666Coiled coilOntology_term=ECO:0000255
HgeneNUCB1chr19:49407711chr19:49513032ENST00000263273+212401_40781462.0Compositional biasNote=Poly-Gln
HgeneNUCB1chr19:49407711chr19:49513032ENST00000405315+313401_40781462.0Compositional biasNote=Poly-Gln
HgeneNUCB1chr19:49407711chr19:49513032ENST00000407032+314401_40781666.6666666666666Compositional biasNote=Poly-Gln
HgeneNUCB1chr19:49407711chr19:49513033ENST00000263273+212401_40781462.0Compositional biasNote=Poly-Gln
HgeneNUCB1chr19:49407711chr19:49513033ENST00000405315+313401_40781462.0Compositional biasNote=Poly-Gln
HgeneNUCB1chr19:49407711chr19:49513033ENST00000407032+314401_40781666.6666666666666Compositional biasNote=Poly-Gln
HgeneNUCB1chr19:49407711chr19:49513032ENST00000263273+212172_21881462.0DNA bindingOntology_term=ECO:0000255
HgeneNUCB1chr19:49407711chr19:49513032ENST00000405315+313172_21881462.0DNA bindingOntology_term=ECO:0000255
HgeneNUCB1chr19:49407711chr19:49513032ENST00000407032+314172_21881666.6666666666666DNA bindingOntology_term=ECO:0000255
HgeneNUCB1chr19:49407711chr19:49513033ENST00000263273+212172_21881462.0DNA bindingOntology_term=ECO:0000255
HgeneNUCB1chr19:49407711chr19:49513033ENST00000405315+313172_21881462.0DNA bindingOntology_term=ECO:0000255
HgeneNUCB1chr19:49407711chr19:49513033ENST00000407032+314172_21881666.6666666666666DNA bindingOntology_term=ECO:0000255
HgeneNUCB1chr19:49407711chr19:49513032ENST00000263273+212240_27581462.0DomainEF-hand 1
HgeneNUCB1chr19:49407711chr19:49513032ENST00000263273+212292_32781462.0DomainEF-hand 2
HgeneNUCB1chr19:49407711chr19:49513032ENST00000405315+313240_27581462.0DomainEF-hand 1
HgeneNUCB1chr19:49407711chr19:49513032ENST00000405315+313292_32781462.0DomainEF-hand 2
HgeneNUCB1chr19:49407711chr19:49513032ENST00000407032+314240_27581666.6666666666666DomainEF-hand 1
HgeneNUCB1chr19:49407711chr19:49513032ENST00000407032+314292_32781666.6666666666666DomainEF-hand 2
HgeneNUCB1chr19:49407711chr19:49513033ENST00000263273+212240_27581462.0DomainEF-hand 1
HgeneNUCB1chr19:49407711chr19:49513033ENST00000263273+212292_32781462.0DomainEF-hand 2
HgeneNUCB1chr19:49407711chr19:49513033ENST00000405315+313240_27581462.0DomainEF-hand 1
HgeneNUCB1chr19:49407711chr19:49513033ENST00000405315+313292_32781462.0DomainEF-hand 2
HgeneNUCB1chr19:49407711chr19:49513033ENST00000407032+314240_27581666.6666666666666DomainEF-hand 1
HgeneNUCB1chr19:49407711chr19:49513033ENST00000407032+314292_32781666.6666666666666DomainEF-hand 2
HgeneNUCB1chr19:49407711chr19:49513032ENST00000263273+212303_33381462.0MotifGBA
HgeneNUCB1chr19:49407711chr19:49513032ENST00000405315+313303_33381462.0MotifGBA
HgeneNUCB1chr19:49407711chr19:49513032ENST00000407032+314303_33381666.6666666666666MotifGBA
HgeneNUCB1chr19:49407711chr19:49513033ENST00000263273+212303_33381462.0MotifGBA
HgeneNUCB1chr19:49407711chr19:49513033ENST00000405315+313303_33381462.0MotifGBA
HgeneNUCB1chr19:49407711chr19:49513033ENST00000407032+314303_33381666.6666666666666MotifGBA
HgeneNUCB1chr19:49407711chr19:49513032ENST00000263273+212228_32181462.0RegionBinds to GNAI2 and GNAI3
HgeneNUCB1chr19:49407711chr19:49513032ENST00000405315+313228_32181462.0RegionBinds to GNAI2 and GNAI3
HgeneNUCB1chr19:49407711chr19:49513032ENST00000407032+314228_32181666.6666666666666RegionBinds to GNAI2 and GNAI3
HgeneNUCB1chr19:49407711chr19:49513033ENST00000263273+212228_32181462.0RegionBinds to GNAI2 and GNAI3
HgeneNUCB1chr19:49407711chr19:49513033ENST00000405315+313228_32181462.0RegionBinds to GNAI2 and GNAI3
HgeneNUCB1chr19:49407711chr19:49513033ENST00000407032+314228_32181666.6666666666666RegionBinds to GNAI2 and GNAI3
TgeneRUVBL2chr19:49407711chr19:49513032ENST0000059509051577_84154464.0Nucleotide bindingNote=ATP
TgeneRUVBL2chr19:49407711chr19:49513033ENST0000059509051577_84154464.0Nucleotide bindingNote=ATP


Top

Fusion Gene Sequence for NUCB1-RUVBL2


check button For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. To have fusion amino acid sequence, we ran ORFfinder and chose the longest ORF among the all predicted ones.
>60762_60762_1_NUCB1-RUVBL2_NUCB1_chr19_49407711_ENST00000263273_RUVBL2_chr19_49513032_ENST00000595090_length(transcript)=1339nt_BP=256nt
AGACCACACTGCCATGCCTCCCTCTGGGCCCCGAGGAACCCTCCTTCTGTTGCCGCTGCTGCTGCTGCTCCTGCTTCGCGCCGTGCTGGC
TGTCCCCCTGGAGCGAGGGGCGCCCAACAAGGAGGAGACCCCTGCGACTGAGAGTCCCGACACAGGCCTGTACTACCACCGGTACCTCCA
GGAGGTCATCGATGTACTGGAGACGGATGGGCATTTCCGAGAGAAGCTGCAGGCTGCCAATGCGGAGGACATCAAGGGCTCCAAGGTGGG
CAAACTGACCCTCAAGACCACAGAGATGGAGACCATCTACGACCTGGGCACCAAGATGATTGAGTCCCTGACCAAGGACAAGGTCCAGGC
CGGGGACGTGATCACCATCGACAAGGCGACGGGCAAGATCTCCAAGCTGGGCCGCTCCTTCACACGCGCCCGCGACTACGACGCTATGGG
CTCCCAGACCAAGTTCGTGCAGTGCCCAGATGGGGAGCTCCAGAAACGCAAGGAGGTGGTGCACACCGTGTCCCTGCACGAGATCGACGT
CATCAACTCTCGCACCCAGGGCTTCCTGGCGCTCTTCTCAGGTGACACAGGGGAGATCAAGTCAGAAGTCCGTGAGCAGATCAATGCCAA
GGTGGCTGAGTGGCGCGAGGAGGGCAAGGCGGAGATCATCCCTGGAGTGCTGTTCATCGACGAGGTCCACATGCTGGACATCGAGAGCTT
CTCCTTCCTCAACCGGGCCCTGGAGAGTGACATGGCGCCTGTCCTGATCATGGCCACCAACCGTGGCATCACGCGAATCCGGGGCACCAG
CTACCAGAGCCCTCACGGCATCCCCATAGACCTGCTGGACCGGCTGCTTATCGTCTCCACCACCCCCTACAGCGAGAAAGACACGAAGCA
GATCCTCCGCATCCGGTGCGAGGAAGAAGATGTGGAGATGAGTGAGGACGCCTACACGGTGCTGACCCGCATCGGGCTGGAGACGTCACT
GCGCTACGCCATCCAGCTCATCACAGCTGCCAGCTTGGTGTGCCGGAAACGCAAGGGTACAGAAGTGCAGGTGGATGACATCAAGCGGGT
CTACTCACTCTTCCTGGACGAGTCCCGCTCCACGCAGTACATGAAGGAGTACCAGGACGCCTTCCTCTTCAACGAACTCAAAGGCGAGAC
CATGGACACCTCCTGAGTTGGATGTCATCCCCCGACCCCACCCTGTTTTCCACCAGAGTTCTGACACTGTGACTCTGTATAAAATGGTTG

>60762_60762_1_NUCB1-RUVBL2_NUCB1_chr19_49407711_ENST00000263273_RUVBL2_chr19_49513032_ENST00000595090_length(amino acids)=390AA_BP=0
MPPSGPRGTLLLLPLLLLLLLRAVLAVPLERGAPNKEETPATESPDTGLYYHRYLQEVIDVLETDGHFREKLQAANAEDIKGSKVGKLTL
KTTEMETIYDLGTKMIESLTKDKVQAGDVITIDKATGKISKLGRSFTRARDYDAMGSQTKFVQCPDGELQKRKEVVHTVSLHEIDVINSR
TQGFLALFSGDTGEIKSEVREQINAKVAEWREEGKAEIIPGVLFIDEVHMLDIESFSFLNRALESDMAPVLIMATNRGITRIRGTSYQSP
HGIPIDLLDRLLIVSTTPYSEKDTKQILRIRCEEEDVEMSEDAYTVLTRIGLETSLRYAIQLITAASLVCRKRKGTEVQVDDIKRVYSLF

--------------------------------------------------------------
>60762_60762_2_NUCB1-RUVBL2_NUCB1_chr19_49407711_ENST00000263273_RUVBL2_chr19_49513032_ENST00000601968_length(transcript)=1106nt_BP=256nt
AGACCACACTGCCATGCCTCCCTCTGGGCCCCGAGGAACCCTCCTTCTGTTGCCGCTGCTGCTGCTGCTCCTGCTTCGCGCCGTGCTGGC
TGTCCCCCTGGAGCGAGGGGCGCCCAACAAGGAGGAGACCCCTGCGACTGAGAGTCCCGACACAGGCCTGTACTACCACCGGTACCTCCA
GGAGGTCATCGATGTACTGGAGACGGATGGGCATTTCCGAGAGAAGCTGCAGGCTGCCAATGCGGAGGACATCAAGGGCTCCAAGGTGGG
CAAACTGACCCTCAAGACCACAGAGATGGAGACCATCTACGACCTGGGCACCAAGATGATTGAGTCCCTGACCAAGGACAAGGTCCAGGC
CGGGGACGTGATCACCATCGACAAGGCGACGGGCAAGATCTCCAAGCTGGGCCGCTCCTTCACACGCGCCCGCGACTACGACGCTATGGG
CTCCCAGACCAAGTTCGTGCAGTGCCCAGATGGGGAGCTCCAGAAACGCAAGGAGGTGGTGCACACCGTGTCCCTGCACGAGATCGACGT
CATCAACTCTCGCACCCAGGGCTTCCTGGCGCTCTTCTCAGGTGACACAGGGGAGATCAAGTCAGAAGTCCGTGAGCAGATCAATGCCAA
GGTGGCTGAGTGGCGCGAGGAGGGCAAGGCGGAGATCATCCCTGGAGTGCTGTTCATCGACGAGGTCCACATGCTGGACATCGAGAGCTT
CTCCTTCCTCAACCGGGCCCTGGAGAGTGACATGGCGCCTGTCCTGATCATGGCCACCAACCGTGGCATCACGCGAATCCGGGGCACCAG
CTACCAGAGCCCTCACGGCATCCCCATAGACCTGCTGGACCGGCTGCTTATCGTCTCCACCACCCCCTACAGCGAGAAAGACACGAAGCA
GATCCTCCGCATCCGGGTACAGAAGTGCAGGTGGATGACATCAAGCGGGTCTACTCACTCTTCCTGGACGAGTCCCGCTCCACGCAGTAC
ATGAAGGAGTACCAGGACGCCTTCCTCTTCAACGAACTCAAAGGCGAGACCATGGACACCTCCTGAGTTGGATGTCATCCCCCGACCCCA

>60762_60762_2_NUCB1-RUVBL2_NUCB1_chr19_49407711_ENST00000263273_RUVBL2_chr19_49513032_ENST00000601968_length(amino acids)=326AA_BP=0
MPPSGPRGTLLLLPLLLLLLLRAVLAVPLERGAPNKEETPATESPDTGLYYHRYLQEVIDVLETDGHFREKLQAANAEDIKGSKVGKLTL
KTTEMETIYDLGTKMIESLTKDKVQAGDVITIDKATGKISKLGRSFTRARDYDAMGSQTKFVQCPDGELQKRKEVVHTVSLHEIDVINSR
TQGFLALFSGDTGEIKSEVREQINAKVAEWREEGKAEIIPGVLFIDEVHMLDIESFSFLNRALESDMAPVLIMATNRGITRIRGTSYQSP

--------------------------------------------------------------
>60762_60762_3_NUCB1-RUVBL2_NUCB1_chr19_49407711_ENST00000263273_RUVBL2_chr19_49513033_ENST00000595090_length(transcript)=1339nt_BP=256nt
AGACCACACTGCCATGCCTCCCTCTGGGCCCCGAGGAACCCTCCTTCTGTTGCCGCTGCTGCTGCTGCTCCTGCTTCGCGCCGTGCTGGC
TGTCCCCCTGGAGCGAGGGGCGCCCAACAAGGAGGAGACCCCTGCGACTGAGAGTCCCGACACAGGCCTGTACTACCACCGGTACCTCCA
GGAGGTCATCGATGTACTGGAGACGGATGGGCATTTCCGAGAGAAGCTGCAGGCTGCCAATGCGGAGGACATCAAGGGCTCCAAGGTGGG
CAAACTGACCCTCAAGACCACAGAGATGGAGACCATCTACGACCTGGGCACCAAGATGATTGAGTCCCTGACCAAGGACAAGGTCCAGGC
CGGGGACGTGATCACCATCGACAAGGCGACGGGCAAGATCTCCAAGCTGGGCCGCTCCTTCACACGCGCCCGCGACTACGACGCTATGGG
CTCCCAGACCAAGTTCGTGCAGTGCCCAGATGGGGAGCTCCAGAAACGCAAGGAGGTGGTGCACACCGTGTCCCTGCACGAGATCGACGT
CATCAACTCTCGCACCCAGGGCTTCCTGGCGCTCTTCTCAGGTGACACAGGGGAGATCAAGTCAGAAGTCCGTGAGCAGATCAATGCCAA
GGTGGCTGAGTGGCGCGAGGAGGGCAAGGCGGAGATCATCCCTGGAGTGCTGTTCATCGACGAGGTCCACATGCTGGACATCGAGAGCTT
CTCCTTCCTCAACCGGGCCCTGGAGAGTGACATGGCGCCTGTCCTGATCATGGCCACCAACCGTGGCATCACGCGAATCCGGGGCACCAG
CTACCAGAGCCCTCACGGCATCCCCATAGACCTGCTGGACCGGCTGCTTATCGTCTCCACCACCCCCTACAGCGAGAAAGACACGAAGCA
GATCCTCCGCATCCGGTGCGAGGAAGAAGATGTGGAGATGAGTGAGGACGCCTACACGGTGCTGACCCGCATCGGGCTGGAGACGTCACT
GCGCTACGCCATCCAGCTCATCACAGCTGCCAGCTTGGTGTGCCGGAAACGCAAGGGTACAGAAGTGCAGGTGGATGACATCAAGCGGGT
CTACTCACTCTTCCTGGACGAGTCCCGCTCCACGCAGTACATGAAGGAGTACCAGGACGCCTTCCTCTTCAACGAACTCAAAGGCGAGAC
CATGGACACCTCCTGAGTTGGATGTCATCCCCCGACCCCACCCTGTTTTCCACCAGAGTTCTGACACTGTGACTCTGTATAAAATGGTTG

>60762_60762_3_NUCB1-RUVBL2_NUCB1_chr19_49407711_ENST00000263273_RUVBL2_chr19_49513033_ENST00000595090_length(amino acids)=390AA_BP=0
MPPSGPRGTLLLLPLLLLLLLRAVLAVPLERGAPNKEETPATESPDTGLYYHRYLQEVIDVLETDGHFREKLQAANAEDIKGSKVGKLTL
KTTEMETIYDLGTKMIESLTKDKVQAGDVITIDKATGKISKLGRSFTRARDYDAMGSQTKFVQCPDGELQKRKEVVHTVSLHEIDVINSR
TQGFLALFSGDTGEIKSEVREQINAKVAEWREEGKAEIIPGVLFIDEVHMLDIESFSFLNRALESDMAPVLIMATNRGITRIRGTSYQSP
HGIPIDLLDRLLIVSTTPYSEKDTKQILRIRCEEEDVEMSEDAYTVLTRIGLETSLRYAIQLITAASLVCRKRKGTEVQVDDIKRVYSLF

--------------------------------------------------------------
>60762_60762_4_NUCB1-RUVBL2_NUCB1_chr19_49407711_ENST00000263273_RUVBL2_chr19_49513033_ENST00000601968_length(transcript)=1106nt_BP=256nt
AGACCACACTGCCATGCCTCCCTCTGGGCCCCGAGGAACCCTCCTTCTGTTGCCGCTGCTGCTGCTGCTCCTGCTTCGCGCCGTGCTGGC
TGTCCCCCTGGAGCGAGGGGCGCCCAACAAGGAGGAGACCCCTGCGACTGAGAGTCCCGACACAGGCCTGTACTACCACCGGTACCTCCA
GGAGGTCATCGATGTACTGGAGACGGATGGGCATTTCCGAGAGAAGCTGCAGGCTGCCAATGCGGAGGACATCAAGGGCTCCAAGGTGGG
CAAACTGACCCTCAAGACCACAGAGATGGAGACCATCTACGACCTGGGCACCAAGATGATTGAGTCCCTGACCAAGGACAAGGTCCAGGC
CGGGGACGTGATCACCATCGACAAGGCGACGGGCAAGATCTCCAAGCTGGGCCGCTCCTTCACACGCGCCCGCGACTACGACGCTATGGG
CTCCCAGACCAAGTTCGTGCAGTGCCCAGATGGGGAGCTCCAGAAACGCAAGGAGGTGGTGCACACCGTGTCCCTGCACGAGATCGACGT
CATCAACTCTCGCACCCAGGGCTTCCTGGCGCTCTTCTCAGGTGACACAGGGGAGATCAAGTCAGAAGTCCGTGAGCAGATCAATGCCAA
GGTGGCTGAGTGGCGCGAGGAGGGCAAGGCGGAGATCATCCCTGGAGTGCTGTTCATCGACGAGGTCCACATGCTGGACATCGAGAGCTT
CTCCTTCCTCAACCGGGCCCTGGAGAGTGACATGGCGCCTGTCCTGATCATGGCCACCAACCGTGGCATCACGCGAATCCGGGGCACCAG
CTACCAGAGCCCTCACGGCATCCCCATAGACCTGCTGGACCGGCTGCTTATCGTCTCCACCACCCCCTACAGCGAGAAAGACACGAAGCA
GATCCTCCGCATCCGGGTACAGAAGTGCAGGTGGATGACATCAAGCGGGTCTACTCACTCTTCCTGGACGAGTCCCGCTCCACGCAGTAC
ATGAAGGAGTACCAGGACGCCTTCCTCTTCAACGAACTCAAAGGCGAGACCATGGACACCTCCTGAGTTGGATGTCATCCCCCGACCCCA

>60762_60762_4_NUCB1-RUVBL2_NUCB1_chr19_49407711_ENST00000263273_RUVBL2_chr19_49513033_ENST00000601968_length(amino acids)=326AA_BP=0
MPPSGPRGTLLLLPLLLLLLLRAVLAVPLERGAPNKEETPATESPDTGLYYHRYLQEVIDVLETDGHFREKLQAANAEDIKGSKVGKLTL
KTTEMETIYDLGTKMIESLTKDKVQAGDVITIDKATGKISKLGRSFTRARDYDAMGSQTKFVQCPDGELQKRKEVVHTVSLHEIDVINSR
TQGFLALFSGDTGEIKSEVREQINAKVAEWREEGKAEIIPGVLFIDEVHMLDIESFSFLNRALESDMAPVLIMATNRGITRIRGTSYQSP

--------------------------------------------------------------
>60762_60762_5_NUCB1-RUVBL2_NUCB1_chr19_49407711_ENST00000405315_RUVBL2_chr19_49513032_ENST00000595090_length(transcript)=1660nt_BP=577nt
GCGGAAGTTATTTTTCCCCCGGCCGGCAGGGAGTTGTAGTTATCTTTGAAAGCCTTCTCTCTCTTTTGGCATAGGCGGGAAATGTGGCGT
CAAGAGGCTGGGATTCCGAGAAAGAAGCGAGGCTTTCACGAAAATGCGAGCGGCTTCGGCAAGGGGCGGGGCCGCTGGACGTGGATGAAA
GCTACAGAGCCAGCGTGGACCAATCAGACCTCTTTGGGGCGGGGCCTCTGTGGATAAGTGGGCGTGGTCTAGGGGGGAAGTCACCAAGAA
CGCACCGGAGGTCCTTGCCCGCCCTGGAAAACGCCCTCTGCGGTGAAGGAGAGACCACACTGCCATGCCTCCCTCTGGGCCCCGAGGAAC
CCTCCTTCTGTTGCCGCTGCTGCTGCTGCTCCTGCTTCGCGCCGTGCTGGCTGTCCCCCTGGAGCGAGGGGCGCCCAACAAGGAGGAGAC
CCCTGCGACTGAGAGTCCCGACACAGGCCTGTACTACCACCGGTACCTCCAGGAGGTCATCGATGTACTGGAGACGGATGGGCATTTCCG
AGAGAAGCTGCAGGCTGCCAATGCGGAGGACATCAAGGGCTCCAAGGTGGGCAAACTGACCCTCAAGACCACAGAGATGGAGACCATCTA
CGACCTGGGCACCAAGATGATTGAGTCCCTGACCAAGGACAAGGTCCAGGCCGGGGACGTGATCACCATCGACAAGGCGACGGGCAAGAT
CTCCAAGCTGGGCCGCTCCTTCACACGCGCCCGCGACTACGACGCTATGGGCTCCCAGACCAAGTTCGTGCAGTGCCCAGATGGGGAGCT
CCAGAAACGCAAGGAGGTGGTGCACACCGTGTCCCTGCACGAGATCGACGTCATCAACTCTCGCACCCAGGGCTTCCTGGCGCTCTTCTC
AGGTGACACAGGGGAGATCAAGTCAGAAGTCCGTGAGCAGATCAATGCCAAGGTGGCTGAGTGGCGCGAGGAGGGCAAGGCGGAGATCAT
CCCTGGAGTGCTGTTCATCGACGAGGTCCACATGCTGGACATCGAGAGCTTCTCCTTCCTCAACCGGGCCCTGGAGAGTGACATGGCGCC
TGTCCTGATCATGGCCACCAACCGTGGCATCACGCGAATCCGGGGCACCAGCTACCAGAGCCCTCACGGCATCCCCATAGACCTGCTGGA
CCGGCTGCTTATCGTCTCCACCACCCCCTACAGCGAGAAAGACACGAAGCAGATCCTCCGCATCCGGTGCGAGGAAGAAGATGTGGAGAT
GAGTGAGGACGCCTACACGGTGCTGACCCGCATCGGGCTGGAGACGTCACTGCGCTACGCCATCCAGCTCATCACAGCTGCCAGCTTGGT
GTGCCGGAAACGCAAGGGTACAGAAGTGCAGGTGGATGACATCAAGCGGGTCTACTCACTCTTCCTGGACGAGTCCCGCTCCACGCAGTA
CATGAAGGAGTACCAGGACGCCTTCCTCTTCAACGAACTCAAAGGCGAGACCATGGACACCTCCTGAGTTGGATGTCATCCCCCGACCCC
ACCCTGTTTTCCACCAGAGTTCTGACACTGTGACTCTGTATAAAATGGTTGGGAAGCTGCACCCACCCTGTGTATGTGTGGTTGCCCTGA

>60762_60762_5_NUCB1-RUVBL2_NUCB1_chr19_49407711_ENST00000405315_RUVBL2_chr19_49513032_ENST00000595090_length(amino acids)=390AA_BP=0
MPPSGPRGTLLLLPLLLLLLLRAVLAVPLERGAPNKEETPATESPDTGLYYHRYLQEVIDVLETDGHFREKLQAANAEDIKGSKVGKLTL
KTTEMETIYDLGTKMIESLTKDKVQAGDVITIDKATGKISKLGRSFTRARDYDAMGSQTKFVQCPDGELQKRKEVVHTVSLHEIDVINSR
TQGFLALFSGDTGEIKSEVREQINAKVAEWREEGKAEIIPGVLFIDEVHMLDIESFSFLNRALESDMAPVLIMATNRGITRIRGTSYQSP
HGIPIDLLDRLLIVSTTPYSEKDTKQILRIRCEEEDVEMSEDAYTVLTRIGLETSLRYAIQLITAASLVCRKRKGTEVQVDDIKRVYSLF

--------------------------------------------------------------
>60762_60762_6_NUCB1-RUVBL2_NUCB1_chr19_49407711_ENST00000405315_RUVBL2_chr19_49513032_ENST00000601968_length(transcript)=1427nt_BP=577nt
GCGGAAGTTATTTTTCCCCCGGCCGGCAGGGAGTTGTAGTTATCTTTGAAAGCCTTCTCTCTCTTTTGGCATAGGCGGGAAATGTGGCGT
CAAGAGGCTGGGATTCCGAGAAAGAAGCGAGGCTTTCACGAAAATGCGAGCGGCTTCGGCAAGGGGCGGGGCCGCTGGACGTGGATGAAA
GCTACAGAGCCAGCGTGGACCAATCAGACCTCTTTGGGGCGGGGCCTCTGTGGATAAGTGGGCGTGGTCTAGGGGGGAAGTCACCAAGAA
CGCACCGGAGGTCCTTGCCCGCCCTGGAAAACGCCCTCTGCGGTGAAGGAGAGACCACACTGCCATGCCTCCCTCTGGGCCCCGAGGAAC
CCTCCTTCTGTTGCCGCTGCTGCTGCTGCTCCTGCTTCGCGCCGTGCTGGCTGTCCCCCTGGAGCGAGGGGCGCCCAACAAGGAGGAGAC
CCCTGCGACTGAGAGTCCCGACACAGGCCTGTACTACCACCGGTACCTCCAGGAGGTCATCGATGTACTGGAGACGGATGGGCATTTCCG
AGAGAAGCTGCAGGCTGCCAATGCGGAGGACATCAAGGGCTCCAAGGTGGGCAAACTGACCCTCAAGACCACAGAGATGGAGACCATCTA
CGACCTGGGCACCAAGATGATTGAGTCCCTGACCAAGGACAAGGTCCAGGCCGGGGACGTGATCACCATCGACAAGGCGACGGGCAAGAT
CTCCAAGCTGGGCCGCTCCTTCACACGCGCCCGCGACTACGACGCTATGGGCTCCCAGACCAAGTTCGTGCAGTGCCCAGATGGGGAGCT
CCAGAAACGCAAGGAGGTGGTGCACACCGTGTCCCTGCACGAGATCGACGTCATCAACTCTCGCACCCAGGGCTTCCTGGCGCTCTTCTC
AGGTGACACAGGGGAGATCAAGTCAGAAGTCCGTGAGCAGATCAATGCCAAGGTGGCTGAGTGGCGCGAGGAGGGCAAGGCGGAGATCAT
CCCTGGAGTGCTGTTCATCGACGAGGTCCACATGCTGGACATCGAGAGCTTCTCCTTCCTCAACCGGGCCCTGGAGAGTGACATGGCGCC
TGTCCTGATCATGGCCACCAACCGTGGCATCACGCGAATCCGGGGCACCAGCTACCAGAGCCCTCACGGCATCCCCATAGACCTGCTGGA
CCGGCTGCTTATCGTCTCCACCACCCCCTACAGCGAGAAAGACACGAAGCAGATCCTCCGCATCCGGGTACAGAAGTGCAGGTGGATGAC
ATCAAGCGGGTCTACTCACTCTTCCTGGACGAGTCCCGCTCCACGCAGTACATGAAGGAGTACCAGGACGCCTTCCTCTTCAACGAACTC

>60762_60762_6_NUCB1-RUVBL2_NUCB1_chr19_49407711_ENST00000405315_RUVBL2_chr19_49513032_ENST00000601968_length(amino acids)=326AA_BP=0
MPPSGPRGTLLLLPLLLLLLLRAVLAVPLERGAPNKEETPATESPDTGLYYHRYLQEVIDVLETDGHFREKLQAANAEDIKGSKVGKLTL
KTTEMETIYDLGTKMIESLTKDKVQAGDVITIDKATGKISKLGRSFTRARDYDAMGSQTKFVQCPDGELQKRKEVVHTVSLHEIDVINSR
TQGFLALFSGDTGEIKSEVREQINAKVAEWREEGKAEIIPGVLFIDEVHMLDIESFSFLNRALESDMAPVLIMATNRGITRIRGTSYQSP

--------------------------------------------------------------
>60762_60762_7_NUCB1-RUVBL2_NUCB1_chr19_49407711_ENST00000405315_RUVBL2_chr19_49513033_ENST00000595090_length(transcript)=1660nt_BP=577nt
GCGGAAGTTATTTTTCCCCCGGCCGGCAGGGAGTTGTAGTTATCTTTGAAAGCCTTCTCTCTCTTTTGGCATAGGCGGGAAATGTGGCGT
CAAGAGGCTGGGATTCCGAGAAAGAAGCGAGGCTTTCACGAAAATGCGAGCGGCTTCGGCAAGGGGCGGGGCCGCTGGACGTGGATGAAA
GCTACAGAGCCAGCGTGGACCAATCAGACCTCTTTGGGGCGGGGCCTCTGTGGATAAGTGGGCGTGGTCTAGGGGGGAAGTCACCAAGAA
CGCACCGGAGGTCCTTGCCCGCCCTGGAAAACGCCCTCTGCGGTGAAGGAGAGACCACACTGCCATGCCTCCCTCTGGGCCCCGAGGAAC
CCTCCTTCTGTTGCCGCTGCTGCTGCTGCTCCTGCTTCGCGCCGTGCTGGCTGTCCCCCTGGAGCGAGGGGCGCCCAACAAGGAGGAGAC
CCCTGCGACTGAGAGTCCCGACACAGGCCTGTACTACCACCGGTACCTCCAGGAGGTCATCGATGTACTGGAGACGGATGGGCATTTCCG
AGAGAAGCTGCAGGCTGCCAATGCGGAGGACATCAAGGGCTCCAAGGTGGGCAAACTGACCCTCAAGACCACAGAGATGGAGACCATCTA
CGACCTGGGCACCAAGATGATTGAGTCCCTGACCAAGGACAAGGTCCAGGCCGGGGACGTGATCACCATCGACAAGGCGACGGGCAAGAT
CTCCAAGCTGGGCCGCTCCTTCACACGCGCCCGCGACTACGACGCTATGGGCTCCCAGACCAAGTTCGTGCAGTGCCCAGATGGGGAGCT
CCAGAAACGCAAGGAGGTGGTGCACACCGTGTCCCTGCACGAGATCGACGTCATCAACTCTCGCACCCAGGGCTTCCTGGCGCTCTTCTC
AGGTGACACAGGGGAGATCAAGTCAGAAGTCCGTGAGCAGATCAATGCCAAGGTGGCTGAGTGGCGCGAGGAGGGCAAGGCGGAGATCAT
CCCTGGAGTGCTGTTCATCGACGAGGTCCACATGCTGGACATCGAGAGCTTCTCCTTCCTCAACCGGGCCCTGGAGAGTGACATGGCGCC
TGTCCTGATCATGGCCACCAACCGTGGCATCACGCGAATCCGGGGCACCAGCTACCAGAGCCCTCACGGCATCCCCATAGACCTGCTGGA
CCGGCTGCTTATCGTCTCCACCACCCCCTACAGCGAGAAAGACACGAAGCAGATCCTCCGCATCCGGTGCGAGGAAGAAGATGTGGAGAT
GAGTGAGGACGCCTACACGGTGCTGACCCGCATCGGGCTGGAGACGTCACTGCGCTACGCCATCCAGCTCATCACAGCTGCCAGCTTGGT
GTGCCGGAAACGCAAGGGTACAGAAGTGCAGGTGGATGACATCAAGCGGGTCTACTCACTCTTCCTGGACGAGTCCCGCTCCACGCAGTA
CATGAAGGAGTACCAGGACGCCTTCCTCTTCAACGAACTCAAAGGCGAGACCATGGACACCTCCTGAGTTGGATGTCATCCCCCGACCCC
ACCCTGTTTTCCACCAGAGTTCTGACACTGTGACTCTGTATAAAATGGTTGGGAAGCTGCACCCACCCTGTGTATGTGTGGTTGCCCTGA

>60762_60762_7_NUCB1-RUVBL2_NUCB1_chr19_49407711_ENST00000405315_RUVBL2_chr19_49513033_ENST00000595090_length(amino acids)=390AA_BP=0
MPPSGPRGTLLLLPLLLLLLLRAVLAVPLERGAPNKEETPATESPDTGLYYHRYLQEVIDVLETDGHFREKLQAANAEDIKGSKVGKLTL
KTTEMETIYDLGTKMIESLTKDKVQAGDVITIDKATGKISKLGRSFTRARDYDAMGSQTKFVQCPDGELQKRKEVVHTVSLHEIDVINSR
TQGFLALFSGDTGEIKSEVREQINAKVAEWREEGKAEIIPGVLFIDEVHMLDIESFSFLNRALESDMAPVLIMATNRGITRIRGTSYQSP
HGIPIDLLDRLLIVSTTPYSEKDTKQILRIRCEEEDVEMSEDAYTVLTRIGLETSLRYAIQLITAASLVCRKRKGTEVQVDDIKRVYSLF

--------------------------------------------------------------
>60762_60762_8_NUCB1-RUVBL2_NUCB1_chr19_49407711_ENST00000405315_RUVBL2_chr19_49513033_ENST00000601968_length(transcript)=1427nt_BP=577nt
GCGGAAGTTATTTTTCCCCCGGCCGGCAGGGAGTTGTAGTTATCTTTGAAAGCCTTCTCTCTCTTTTGGCATAGGCGGGAAATGTGGCGT
CAAGAGGCTGGGATTCCGAGAAAGAAGCGAGGCTTTCACGAAAATGCGAGCGGCTTCGGCAAGGGGCGGGGCCGCTGGACGTGGATGAAA
GCTACAGAGCCAGCGTGGACCAATCAGACCTCTTTGGGGCGGGGCCTCTGTGGATAAGTGGGCGTGGTCTAGGGGGGAAGTCACCAAGAA
CGCACCGGAGGTCCTTGCCCGCCCTGGAAAACGCCCTCTGCGGTGAAGGAGAGACCACACTGCCATGCCTCCCTCTGGGCCCCGAGGAAC
CCTCCTTCTGTTGCCGCTGCTGCTGCTGCTCCTGCTTCGCGCCGTGCTGGCTGTCCCCCTGGAGCGAGGGGCGCCCAACAAGGAGGAGAC
CCCTGCGACTGAGAGTCCCGACACAGGCCTGTACTACCACCGGTACCTCCAGGAGGTCATCGATGTACTGGAGACGGATGGGCATTTCCG
AGAGAAGCTGCAGGCTGCCAATGCGGAGGACATCAAGGGCTCCAAGGTGGGCAAACTGACCCTCAAGACCACAGAGATGGAGACCATCTA
CGACCTGGGCACCAAGATGATTGAGTCCCTGACCAAGGACAAGGTCCAGGCCGGGGACGTGATCACCATCGACAAGGCGACGGGCAAGAT
CTCCAAGCTGGGCCGCTCCTTCACACGCGCCCGCGACTACGACGCTATGGGCTCCCAGACCAAGTTCGTGCAGTGCCCAGATGGGGAGCT
CCAGAAACGCAAGGAGGTGGTGCACACCGTGTCCCTGCACGAGATCGACGTCATCAACTCTCGCACCCAGGGCTTCCTGGCGCTCTTCTC
AGGTGACACAGGGGAGATCAAGTCAGAAGTCCGTGAGCAGATCAATGCCAAGGTGGCTGAGTGGCGCGAGGAGGGCAAGGCGGAGATCAT
CCCTGGAGTGCTGTTCATCGACGAGGTCCACATGCTGGACATCGAGAGCTTCTCCTTCCTCAACCGGGCCCTGGAGAGTGACATGGCGCC
TGTCCTGATCATGGCCACCAACCGTGGCATCACGCGAATCCGGGGCACCAGCTACCAGAGCCCTCACGGCATCCCCATAGACCTGCTGGA
CCGGCTGCTTATCGTCTCCACCACCCCCTACAGCGAGAAAGACACGAAGCAGATCCTCCGCATCCGGGTACAGAAGTGCAGGTGGATGAC
ATCAAGCGGGTCTACTCACTCTTCCTGGACGAGTCCCGCTCCACGCAGTACATGAAGGAGTACCAGGACGCCTTCCTCTTCAACGAACTC

>60762_60762_8_NUCB1-RUVBL2_NUCB1_chr19_49407711_ENST00000405315_RUVBL2_chr19_49513033_ENST00000601968_length(amino acids)=326AA_BP=0
MPPSGPRGTLLLLPLLLLLLLRAVLAVPLERGAPNKEETPATESPDTGLYYHRYLQEVIDVLETDGHFREKLQAANAEDIKGSKVGKLTL
KTTEMETIYDLGTKMIESLTKDKVQAGDVITIDKATGKISKLGRSFTRARDYDAMGSQTKFVQCPDGELQKRKEVVHTVSLHEIDVINSR
TQGFLALFSGDTGEIKSEVREQINAKVAEWREEGKAEIIPGVLFIDEVHMLDIESFSFLNRALESDMAPVLIMATNRGITRIRGTSYQSP

--------------------------------------------------------------
>60762_60762_9_NUCB1-RUVBL2_NUCB1_chr19_49407711_ENST00000407032_RUVBL2_chr19_49513032_ENST00000595090_length(transcript)=1390nt_BP=307nt
CGCACCGGAGGTCCTTGCCCGCCCTGGAAAACGCCCTCTGCGGTGAAGGAGAGACCACACTGCCATGCCTCCCTCTGGGCCCCGAGGAAC
CCTCCTTCTGTTGCCGCTGCTGCTGCTGCTCCTGCTTCGCGCCGTGCTGGCTGTCCCCCTGGAGCGAGGGGCGCCCAACAAGGAGGAGAC
CCCTGCGACTGAGAGTCCCGACACAGGCCTGTACTACCACCGGTACCTCCAGGAGGTCATCGATGTACTGGAGACGGATGGGCATTTCCG
AGAGAAGCTGCAGGCTGCCAATGCGGAGGACATCAAGGGCTCCAAGGTGGGCAAACTGACCCTCAAGACCACAGAGATGGAGACCATCTA
CGACCTGGGCACCAAGATGATTGAGTCCCTGACCAAGGACAAGGTCCAGGCCGGGGACGTGATCACCATCGACAAGGCGACGGGCAAGAT
CTCCAAGCTGGGCCGCTCCTTCACACGCGCCCGCGACTACGACGCTATGGGCTCCCAGACCAAGTTCGTGCAGTGCCCAGATGGGGAGCT
CCAGAAACGCAAGGAGGTGGTGCACACCGTGTCCCTGCACGAGATCGACGTCATCAACTCTCGCACCCAGGGCTTCCTGGCGCTCTTCTC
AGGTGACACAGGGGAGATCAAGTCAGAAGTCCGTGAGCAGATCAATGCCAAGGTGGCTGAGTGGCGCGAGGAGGGCAAGGCGGAGATCAT
CCCTGGAGTGCTGTTCATCGACGAGGTCCACATGCTGGACATCGAGAGCTTCTCCTTCCTCAACCGGGCCCTGGAGAGTGACATGGCGCC
TGTCCTGATCATGGCCACCAACCGTGGCATCACGCGAATCCGGGGCACCAGCTACCAGAGCCCTCACGGCATCCCCATAGACCTGCTGGA
CCGGCTGCTTATCGTCTCCACCACCCCCTACAGCGAGAAAGACACGAAGCAGATCCTCCGCATCCGGTGCGAGGAAGAAGATGTGGAGAT
GAGTGAGGACGCCTACACGGTGCTGACCCGCATCGGGCTGGAGACGTCACTGCGCTACGCCATCCAGCTCATCACAGCTGCCAGCTTGGT
GTGCCGGAAACGCAAGGGTACAGAAGTGCAGGTGGATGACATCAAGCGGGTCTACTCACTCTTCCTGGACGAGTCCCGCTCCACGCAGTA
CATGAAGGAGTACCAGGACGCCTTCCTCTTCAACGAACTCAAAGGCGAGACCATGGACACCTCCTGAGTTGGATGTCATCCCCCGACCCC
ACCCTGTTTTCCACCAGAGTTCTGACACTGTGACTCTGTATAAAATGGTTGGGAAGCTGCACCCACCCTGTGTATGTGTGGTTGCCCTGA

>60762_60762_9_NUCB1-RUVBL2_NUCB1_chr19_49407711_ENST00000407032_RUVBL2_chr19_49513032_ENST00000595090_length(amino acids)=390AA_BP=0
MPPSGPRGTLLLLPLLLLLLLRAVLAVPLERGAPNKEETPATESPDTGLYYHRYLQEVIDVLETDGHFREKLQAANAEDIKGSKVGKLTL
KTTEMETIYDLGTKMIESLTKDKVQAGDVITIDKATGKISKLGRSFTRARDYDAMGSQTKFVQCPDGELQKRKEVVHTVSLHEIDVINSR
TQGFLALFSGDTGEIKSEVREQINAKVAEWREEGKAEIIPGVLFIDEVHMLDIESFSFLNRALESDMAPVLIMATNRGITRIRGTSYQSP
HGIPIDLLDRLLIVSTTPYSEKDTKQILRIRCEEEDVEMSEDAYTVLTRIGLETSLRYAIQLITAASLVCRKRKGTEVQVDDIKRVYSLF

--------------------------------------------------------------
>60762_60762_10_NUCB1-RUVBL2_NUCB1_chr19_49407711_ENST00000407032_RUVBL2_chr19_49513032_ENST00000601968_length(transcript)=1157nt_BP=307nt
CGCACCGGAGGTCCTTGCCCGCCCTGGAAAACGCCCTCTGCGGTGAAGGAGAGACCACACTGCCATGCCTCCCTCTGGGCCCCGAGGAAC
CCTCCTTCTGTTGCCGCTGCTGCTGCTGCTCCTGCTTCGCGCCGTGCTGGCTGTCCCCCTGGAGCGAGGGGCGCCCAACAAGGAGGAGAC
CCCTGCGACTGAGAGTCCCGACACAGGCCTGTACTACCACCGGTACCTCCAGGAGGTCATCGATGTACTGGAGACGGATGGGCATTTCCG
AGAGAAGCTGCAGGCTGCCAATGCGGAGGACATCAAGGGCTCCAAGGTGGGCAAACTGACCCTCAAGACCACAGAGATGGAGACCATCTA
CGACCTGGGCACCAAGATGATTGAGTCCCTGACCAAGGACAAGGTCCAGGCCGGGGACGTGATCACCATCGACAAGGCGACGGGCAAGAT
CTCCAAGCTGGGCCGCTCCTTCACACGCGCCCGCGACTACGACGCTATGGGCTCCCAGACCAAGTTCGTGCAGTGCCCAGATGGGGAGCT
CCAGAAACGCAAGGAGGTGGTGCACACCGTGTCCCTGCACGAGATCGACGTCATCAACTCTCGCACCCAGGGCTTCCTGGCGCTCTTCTC
AGGTGACACAGGGGAGATCAAGTCAGAAGTCCGTGAGCAGATCAATGCCAAGGTGGCTGAGTGGCGCGAGGAGGGCAAGGCGGAGATCAT
CCCTGGAGTGCTGTTCATCGACGAGGTCCACATGCTGGACATCGAGAGCTTCTCCTTCCTCAACCGGGCCCTGGAGAGTGACATGGCGCC
TGTCCTGATCATGGCCACCAACCGTGGCATCACGCGAATCCGGGGCACCAGCTACCAGAGCCCTCACGGCATCCCCATAGACCTGCTGGA
CCGGCTGCTTATCGTCTCCACCACCCCCTACAGCGAGAAAGACACGAAGCAGATCCTCCGCATCCGGGTACAGAAGTGCAGGTGGATGAC
ATCAAGCGGGTCTACTCACTCTTCCTGGACGAGTCCCGCTCCACGCAGTACATGAAGGAGTACCAGGACGCCTTCCTCTTCAACGAACTC

>60762_60762_10_NUCB1-RUVBL2_NUCB1_chr19_49407711_ENST00000407032_RUVBL2_chr19_49513032_ENST00000601968_length(amino acids)=326AA_BP=0
MPPSGPRGTLLLLPLLLLLLLRAVLAVPLERGAPNKEETPATESPDTGLYYHRYLQEVIDVLETDGHFREKLQAANAEDIKGSKVGKLTL
KTTEMETIYDLGTKMIESLTKDKVQAGDVITIDKATGKISKLGRSFTRARDYDAMGSQTKFVQCPDGELQKRKEVVHTVSLHEIDVINSR
TQGFLALFSGDTGEIKSEVREQINAKVAEWREEGKAEIIPGVLFIDEVHMLDIESFSFLNRALESDMAPVLIMATNRGITRIRGTSYQSP

--------------------------------------------------------------
>60762_60762_11_NUCB1-RUVBL2_NUCB1_chr19_49407711_ENST00000407032_RUVBL2_chr19_49513033_ENST00000595090_length(transcript)=1390nt_BP=307nt
CGCACCGGAGGTCCTTGCCCGCCCTGGAAAACGCCCTCTGCGGTGAAGGAGAGACCACACTGCCATGCCTCCCTCTGGGCCCCGAGGAAC
CCTCCTTCTGTTGCCGCTGCTGCTGCTGCTCCTGCTTCGCGCCGTGCTGGCTGTCCCCCTGGAGCGAGGGGCGCCCAACAAGGAGGAGAC
CCCTGCGACTGAGAGTCCCGACACAGGCCTGTACTACCACCGGTACCTCCAGGAGGTCATCGATGTACTGGAGACGGATGGGCATTTCCG
AGAGAAGCTGCAGGCTGCCAATGCGGAGGACATCAAGGGCTCCAAGGTGGGCAAACTGACCCTCAAGACCACAGAGATGGAGACCATCTA
CGACCTGGGCACCAAGATGATTGAGTCCCTGACCAAGGACAAGGTCCAGGCCGGGGACGTGATCACCATCGACAAGGCGACGGGCAAGAT
CTCCAAGCTGGGCCGCTCCTTCACACGCGCCCGCGACTACGACGCTATGGGCTCCCAGACCAAGTTCGTGCAGTGCCCAGATGGGGAGCT
CCAGAAACGCAAGGAGGTGGTGCACACCGTGTCCCTGCACGAGATCGACGTCATCAACTCTCGCACCCAGGGCTTCCTGGCGCTCTTCTC
AGGTGACACAGGGGAGATCAAGTCAGAAGTCCGTGAGCAGATCAATGCCAAGGTGGCTGAGTGGCGCGAGGAGGGCAAGGCGGAGATCAT
CCCTGGAGTGCTGTTCATCGACGAGGTCCACATGCTGGACATCGAGAGCTTCTCCTTCCTCAACCGGGCCCTGGAGAGTGACATGGCGCC
TGTCCTGATCATGGCCACCAACCGTGGCATCACGCGAATCCGGGGCACCAGCTACCAGAGCCCTCACGGCATCCCCATAGACCTGCTGGA
CCGGCTGCTTATCGTCTCCACCACCCCCTACAGCGAGAAAGACACGAAGCAGATCCTCCGCATCCGGTGCGAGGAAGAAGATGTGGAGAT
GAGTGAGGACGCCTACACGGTGCTGACCCGCATCGGGCTGGAGACGTCACTGCGCTACGCCATCCAGCTCATCACAGCTGCCAGCTTGGT
GTGCCGGAAACGCAAGGGTACAGAAGTGCAGGTGGATGACATCAAGCGGGTCTACTCACTCTTCCTGGACGAGTCCCGCTCCACGCAGTA
CATGAAGGAGTACCAGGACGCCTTCCTCTTCAACGAACTCAAAGGCGAGACCATGGACACCTCCTGAGTTGGATGTCATCCCCCGACCCC
ACCCTGTTTTCCACCAGAGTTCTGACACTGTGACTCTGTATAAAATGGTTGGGAAGCTGCACCCACCCTGTGTATGTGTGGTTGCCCTGA

>60762_60762_11_NUCB1-RUVBL2_NUCB1_chr19_49407711_ENST00000407032_RUVBL2_chr19_49513033_ENST00000595090_length(amino acids)=390AA_BP=0
MPPSGPRGTLLLLPLLLLLLLRAVLAVPLERGAPNKEETPATESPDTGLYYHRYLQEVIDVLETDGHFREKLQAANAEDIKGSKVGKLTL
KTTEMETIYDLGTKMIESLTKDKVQAGDVITIDKATGKISKLGRSFTRARDYDAMGSQTKFVQCPDGELQKRKEVVHTVSLHEIDVINSR
TQGFLALFSGDTGEIKSEVREQINAKVAEWREEGKAEIIPGVLFIDEVHMLDIESFSFLNRALESDMAPVLIMATNRGITRIRGTSYQSP
HGIPIDLLDRLLIVSTTPYSEKDTKQILRIRCEEEDVEMSEDAYTVLTRIGLETSLRYAIQLITAASLVCRKRKGTEVQVDDIKRVYSLF

--------------------------------------------------------------
>60762_60762_12_NUCB1-RUVBL2_NUCB1_chr19_49407711_ENST00000407032_RUVBL2_chr19_49513033_ENST00000601968_length(transcript)=1157nt_BP=307nt
CGCACCGGAGGTCCTTGCCCGCCCTGGAAAACGCCCTCTGCGGTGAAGGAGAGACCACACTGCCATGCCTCCCTCTGGGCCCCGAGGAAC
CCTCCTTCTGTTGCCGCTGCTGCTGCTGCTCCTGCTTCGCGCCGTGCTGGCTGTCCCCCTGGAGCGAGGGGCGCCCAACAAGGAGGAGAC
CCCTGCGACTGAGAGTCCCGACACAGGCCTGTACTACCACCGGTACCTCCAGGAGGTCATCGATGTACTGGAGACGGATGGGCATTTCCG
AGAGAAGCTGCAGGCTGCCAATGCGGAGGACATCAAGGGCTCCAAGGTGGGCAAACTGACCCTCAAGACCACAGAGATGGAGACCATCTA
CGACCTGGGCACCAAGATGATTGAGTCCCTGACCAAGGACAAGGTCCAGGCCGGGGACGTGATCACCATCGACAAGGCGACGGGCAAGAT
CTCCAAGCTGGGCCGCTCCTTCACACGCGCCCGCGACTACGACGCTATGGGCTCCCAGACCAAGTTCGTGCAGTGCCCAGATGGGGAGCT
CCAGAAACGCAAGGAGGTGGTGCACACCGTGTCCCTGCACGAGATCGACGTCATCAACTCTCGCACCCAGGGCTTCCTGGCGCTCTTCTC
AGGTGACACAGGGGAGATCAAGTCAGAAGTCCGTGAGCAGATCAATGCCAAGGTGGCTGAGTGGCGCGAGGAGGGCAAGGCGGAGATCAT
CCCTGGAGTGCTGTTCATCGACGAGGTCCACATGCTGGACATCGAGAGCTTCTCCTTCCTCAACCGGGCCCTGGAGAGTGACATGGCGCC
TGTCCTGATCATGGCCACCAACCGTGGCATCACGCGAATCCGGGGCACCAGCTACCAGAGCCCTCACGGCATCCCCATAGACCTGCTGGA
CCGGCTGCTTATCGTCTCCACCACCCCCTACAGCGAGAAAGACACGAAGCAGATCCTCCGCATCCGGGTACAGAAGTGCAGGTGGATGAC
ATCAAGCGGGTCTACTCACTCTTCCTGGACGAGTCCCGCTCCACGCAGTACATGAAGGAGTACCAGGACGCCTTCCTCTTCAACGAACTC

>60762_60762_12_NUCB1-RUVBL2_NUCB1_chr19_49407711_ENST00000407032_RUVBL2_chr19_49513033_ENST00000601968_length(amino acids)=326AA_BP=0
MPPSGPRGTLLLLPLLLLLLLRAVLAVPLERGAPNKEETPATESPDTGLYYHRYLQEVIDVLETDGHFREKLQAANAEDIKGSKVGKLTL
KTTEMETIYDLGTKMIESLTKDKVQAGDVITIDKATGKISKLGRSFTRARDYDAMGSQTKFVQCPDGELQKRKEVVHTVSLHEIDVINSR
TQGFLALFSGDTGEIKSEVREQINAKVAEWREEGKAEIIPGVLFIDEVHMLDIESFSFLNRALESDMAPVLIMATNRGITRIRGTSYQSP

--------------------------------------------------------------

Top

Fusion Gene PPI Analysis for NUCB1-RUVBL2


check button Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in

ChiPPI page.


check button Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160)
HgeneHgene's interactorsTgeneTgene's interactors


check button - Retained PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenStill interaction with


check button - Lost PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


check button - Retained PPIs, but lost function due to frame-shift fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


Top

Related Drugs for NUCB1-RUVBL2


check button Drugs targeting genes involved in this fusion gene.
(DrugBank Version 5.1.8 2021-05-08)
PartnerGeneUniProtAccDrugBank IDDrug nameDrug activityDrug typeDrug status

Top

Related Diseases for NUCB1-RUVBL2


check button Diseases associated with fusion partners.
(DisGeNet 4.0)
PartnerGeneDisease IDDisease name# pubmedsSource