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Center for Computational Systems Medicine
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Fusion Gene Summary

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Fusion Gene ORF analysis

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Fusion Genomic Features

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Fusion Protein Features

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Fusion Gene Sequence

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Fusion Gene PPI analysis

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Related Drugs

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Related Diseases

Fusion gene:NUP153-DTNBP1 (FusionGDB2 ID:60972)

Fusion Gene Summary for NUP153-DTNBP1

check button Fusion gene summary
Fusion gene informationFusion gene name: NUP153-DTNBP1
Fusion gene ID: 60972
HgeneTgene
Gene symbol

NUP153

DTNBP1

Gene ID

9972

84062

Gene namenucleoporin 153dystrobrevin binding protein 1
SynonymsHNUP153|N153BLOC1S8|DBND|HPS7|My031|SDY
Cytomap

6p22.3

6p22.3

Type of geneprotein-codingprotein-coding
Descriptionnuclear pore complex protein Nup153153 kDa nucleoporinnuclear pore complex protein hnup153nucleoporin 153kDnucleoporin 153kDanucleoporin Nup153dysbindinBLOC-1 subunit 8Hermansky-Pudlak syndrome 7 proteinbiogenesis of lysosomal organelles complex-1, subunit 8biogenesis of lysosome-related organelles complex 1 subunit 8dysbindin-1
Modification date2020031320200313
UniProtAcc.

Q96EV8

Ensembl transtripts involved in fusion geneENST00000262077, ENST00000537253, 
ENST00000338950, ENST00000344537, 
ENST00000355917, ENST00000462989, 
Fusion gene scores* DoF score14 X 11 X 10=154015 X 8 X 9=1080
# samples 1617
** MAII scorelog2(16/1540*10)=-3.2667865406949
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0		log2(17/1080*10)=-2.66742466091313
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0
Context

PubMed: NUP153 [Title/Abstract] AND DTNBP1 [Title/Abstract] AND fusion [Title/Abstract]

Most frequent breakpointDTNBP1(15651544)-NUP153(17640295), # samples:1
NUP153(17646298)-DTNBP1(15524900), # samples:3
Anticipated loss of major functional domain due to fusion event.DTNBP1-NUP153 seems lost the major protein functional domain in Tgene partner, which is a cell metabolism gene due to the frame-shifted ORF.
DTNBP1-NUP153 seems lost the major protein functional domain in Tgene partner, which is a essential gene due to the frame-shifted ORF.
* DoF score (Degree of Frequency) = # partners X # break points X # cancer types
** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)

check button Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez
PartnerGeneGO IDGO termPubMed ID
HgeneNUP153

GO:0046832

negative regulation of RNA export from nucleus

22253824

TgeneDTNBP1

GO:0031175

neuron projection development

16980328


check buttonFusion gene breakpoints across NUP153 (5'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check buttonFusion gene breakpoints across DTNBP1 (3'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check button Fusion gene information from two resources (ChiTars 5.0 and ChimerDB 4.0)
* All genome coordinats were lifted-over on hg19.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
SourceDiseaseSampleHgeneHchrHbpHstrandTgeneTchrTbpTstrand
ChimerDB4BLCATCGA-PQ-A6FI-01ANUP153chr6

17646298

-DTNBP1chr6

15524900

-


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Fusion Gene ORF analysis for NUP153-DTNBP1

check button Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
ORFHenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrand
In-frameENST00000262077ENST00000338950NUP153chr6

17646298

-DTNBP1chr6

15524900

-
In-frameENST00000262077ENST00000344537NUP153chr6

17646298

-DTNBP1chr6

15524900

-
In-frameENST00000262077ENST00000355917NUP153chr6

17646298

-DTNBP1chr6

15524900

-
In-frameENST00000262077ENST00000462989NUP153chr6

17646298

-DTNBP1chr6

15524900

-
In-frameENST00000537253ENST00000338950NUP153chr6

17646298

-DTNBP1chr6

15524900

-
In-frameENST00000537253ENST00000344537NUP153chr6

17646298

-DTNBP1chr6

15524900

-
In-frameENST00000537253ENST00000355917NUP153chr6

17646298

-DTNBP1chr6

15524900

-
In-frameENST00000537253ENST00000462989NUP153chr6

17646298

-DTNBP1chr6

15524900

-

check buttonORFfinder result based on the fusion transcript sequence of in-frame fusion genes.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandSeq length
(transcript)		BP loci
(transcript)		Predicted start
(transcript)		Predicted stop
(transcript)		Seq length
(amino acids)
ENST00000262077NUP153chr617646298-ENST00000344537DTNBP1chr615524900-2283172002108702
ENST00000262077NUP153chr617646298-ENST00000355917DTNBP1chr615524900-2274172002108702
ENST00000262077NUP153chr617646298-ENST00000338950DTNBP1chr615524900-2827172001964654
ENST00000262077NUP153chr617646298-ENST00000462989DTNBP1chr615524900-2277172002108702
ENST00000537253NUP153chr617646298-ENST00000344537DTNBP1chr615524900-24141851382239733
ENST00000537253NUP153chr617646298-ENST00000355917DTNBP1chr615524900-24051851382239733
ENST00000537253NUP153chr617646298-ENST00000338950DTNBP1chr615524900-29581851382095685
ENST00000537253NUP153chr617646298-ENST00000462989DTNBP1chr615524900-24081851382239733

check buttonDeepORF prediction of the coding potential based on the fusion transcript sequence of in-frame fusion genes. DeepORF is a coding potential classifier based on convolutional neural network by comparing the real Ribo-seq data. If the no-coding score < 0.5 and coding score > 0.5, then the in-frame fusion transcript is predicted as being likely translated.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandNo-coding scoreCoding score
ENST00000262077ENST00000344537NUP153chr617646298-DTNBP1chr615524900-0.0013382040.99866176
ENST00000262077ENST00000355917NUP153chr617646298-DTNBP1chr615524900-0.0013193480.99868065
ENST00000262077ENST00000338950NUP153chr617646298-DTNBP1chr615524900-0.0022402550.9977597
ENST00000262077ENST00000462989NUP153chr617646298-DTNBP1chr615524900-0.0012953210.9987047
ENST00000537253ENST00000344537NUP153chr617646298-DTNBP1chr615524900-0.0016975080.99830246
ENST00000537253ENST00000355917NUP153chr617646298-DTNBP1chr615524900-0.0016829010.9983171
ENST00000537253ENST00000338950NUP153chr617646298-DTNBP1chr615524900-0.0026365080.9973635
ENST00000537253ENST00000462989NUP153chr617646298-DTNBP1chr615524900-0.0016525120.9983475

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Fusion Genomic Features for NUP153-DTNBP1


check buttonFusionAI prediction of the potential fusion gene breakpoint based on the pre-mature RNA sequence context (+/- 5kb of individual partner genes, total 20kb length sequence). FusionAI is a fusion gene breakpoint classifier based on convolutional neural network by comparing the fusion positive and negative sequence context of ~ 20K fusion gene data. From here, we can have the relative potentency of the 20K genomic sequence how individual sequnce will be likely used as the gene fusion breakpoints.
HgeneHchrHbpHstrandTgeneTchrTbpTstrand1-pp (fusion gene breakpoint)

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions. We integrated a total of 44 different types of human genomic feature loci information across five big categories including virus integration sites, repeats, structural variants, chromatin states, and gene expression regulation. More details are in help page.
genomic feature

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions that are ovelapped with the top 1% feature importance score regions. More details are in help page.

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Fusion Protein Features for NUP153-DTNBP1


check button Four levels of functional features of fusion genes
Go to FGviewer search page for the most frequent breakpoint (https://ccsmweb.uth.edu/FGviewer/chr6:15651544/chr6:17640295)
- FGviewer provides the online visualization of the retention search of the protein functional features across DNA, RNA, protein, and pathological levels.
- How to search
1. Put your fusion gene symbol.
2. Press the tab key until there will be shown the breakpoint information filled.
4. Go down and press 'Search' tab twice.
4. Go down to have the hyperlink of the search result.
5. Click the hyperlink.
6. See the FGviewer result for your fusion gene.
FGviewer

check buttonMain function of each fusion partner protein. (from UniProt)
HgeneTgene
.DTNBP1

Q96EV8

FUNCTION: Transcriptional activator which is required for calcium-dependent dendritic growth and branching in cortical neurons. Recruits CREB-binding protein (CREBBP) to nuclear bodies. Component of the CREST-BRG1 complex, a multiprotein complex that regulates promoter activation by orchestrating a calcium-dependent release of a repressor complex and a recruitment of an activator complex. In resting neurons, transcription of the c-FOS promoter is inhibited by BRG1-dependent recruitment of a phospho-RB1-HDAC1 repressor complex. Upon calcium influx, RB1 is dephosphorylated by calcineurin, which leads to release of the repressor complex. At the same time, there is increased recruitment of CREBBP to the promoter by a CREST-dependent mechanism, which leads to transcriptional activation. The CREST-BRG1 complex also binds to the NR2B promoter, and activity-dependent induction of NR2B expression involves a release of HDAC1 and recruitment of CREBBP (By similarity). {ECO:0000250}.FUNCTION: Component of the BLOC-1 complex, a complex that is required for normal biogenesis of lysosome-related organelles (LRO), such as platelet dense granules and melanosomes. In concert with the AP-3 complex, the BLOC-1 complex is required to target membrane protein cargos into vesicles assembled at cell bodies for delivery into neurites and nerve terminals. The BLOC-1 complex, in association with SNARE proteins, is also proposed to be involved in neurite extension. Associates with the BLOC-2 complex to facilitate the transport of TYRP1 independent of AP-3 function. Plays a role in synaptic vesicle trafficking and in neurotransmitter release. Plays a role in the regulation of cell surface exposure of DRD2. May play a role in actin cytoskeleton reorganization and neurite outgrowth. May modulate MAPK8 phosphorylation. Appears to promote neuronal transmission and viability through regulating the expression of SNAP25 and SYN1, modulating PI3-kinase-Akt signaling and influencing glutamatergic release. Regulates the expression of SYN1 through binding to its promoter. Modulates prefrontal cortical activity via the dopamine/D2 pathway. {ECO:0000269|PubMed:15345706, ECO:0000269|PubMed:16837549, ECO:0000269|PubMed:17182842, ECO:0000269|PubMed:17989303, ECO:0000269|PubMed:19094965, ECO:0000269|PubMed:20180862, ECO:0000269|PubMed:20921223}.

check buttonRetention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at

download page


* Minus value of BPloci means that the break pointn is located before the CDS.
- In-frame and retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneNUP153chr6:17646298chr6:15524900ENST00000262077-1422443_4475731476.0Compositional biasNote=Poly-Gly
HgeneNUP153chr6:17646298chr6:15524900ENST00000262077-14224_145731476.0Compositional biasNote=Gly-rich
HgeneNUP153chr6:17646298chr6:15524900ENST00000262077-1422236_2375731476.0Repeat1

- In-frame and not-retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneNUP153chr6:17646298chr6:15524900ENST00000262077-14221350_14755731476.0Region(Microbial infection) Interacts with HIV-1 capsid protein p24 (CA)
HgeneNUP153chr6:17646298chr6:15524900ENST00000262077-1422236_14185731476.0Region29 X 2 AA repeats of F-G
HgeneNUP153chr6:17646298chr6:15524900ENST00000262077-14221000_10015731476.0Repeat9
HgeneNUP153chr6:17646298chr6:15524900ENST00000262077-14221024_10255731476.0Repeat10
HgeneNUP153chr6:17646298chr6:15524900ENST00000262077-14221084_10855731476.0Repeat11
HgeneNUP153chr6:17646298chr6:15524900ENST00000262077-14221118_11195731476.0Repeat12
HgeneNUP153chr6:17646298chr6:15524900ENST00000262077-14221135_11365731476.0Repeat13
HgeneNUP153chr6:17646298chr6:15524900ENST00000262077-14221173_11745731476.0Repeat14
HgeneNUP153chr6:17646298chr6:15524900ENST00000262077-14221212_12135731476.0Repeat15
HgeneNUP153chr6:17646298chr6:15524900ENST00000262077-14221228_12295731476.0Repeat16
HgeneNUP153chr6:17646298chr6:15524900ENST00000262077-14221240_12415731476.0Repeat17
HgeneNUP153chr6:17646298chr6:15524900ENST00000262077-14221275_12765731476.0Repeat18
HgeneNUP153chr6:17646298chr6:15524900ENST00000262077-14221289_12905731476.0Repeat19
HgeneNUP153chr6:17646298chr6:15524900ENST00000262077-14221291_12925731476.0Repeat20
HgeneNUP153chr6:17646298chr6:15524900ENST00000262077-14221306_13075731476.0Repeat21
HgeneNUP153chr6:17646298chr6:15524900ENST00000262077-14221319_13205731476.0Repeat22
HgeneNUP153chr6:17646298chr6:15524900ENST00000262077-14221327_13285731476.0Repeat23
HgeneNUP153chr6:17646298chr6:15524900ENST00000262077-14221341_13425731476.0Repeat24
HgeneNUP153chr6:17646298chr6:15524900ENST00000262077-14221362_13635731476.0Repeat25
HgeneNUP153chr6:17646298chr6:15524900ENST00000262077-14221374_13755731476.0Repeat26
HgeneNUP153chr6:17646298chr6:15524900ENST00000262077-14221383_13845731476.0Repeat27
HgeneNUP153chr6:17646298chr6:15524900ENST00000262077-14221397_13985731476.0Repeat28
HgeneNUP153chr6:17646298chr6:15524900ENST00000262077-14221417_14185731476.0Repeat29
HgeneNUP153chr6:17646298chr6:15524900ENST00000262077-1422652_6535731476.0Repeat2
HgeneNUP153chr6:17646298chr6:15524900ENST00000262077-1422715_7165731476.0Repeat3
HgeneNUP153chr6:17646298chr6:15524900ENST00000262077-1422786_7875731476.0Repeat4
HgeneNUP153chr6:17646298chr6:15524900ENST00000262077-1422905_9065731476.0Repeat5
HgeneNUP153chr6:17646298chr6:15524900ENST00000262077-1422926_9275731476.0Repeat6
HgeneNUP153chr6:17646298chr6:15524900ENST00000262077-1422961_9625731476.0Repeat7
HgeneNUP153chr6:17646298chr6:15524900ENST00000262077-1422983_9845731476.0Repeat8
HgeneNUP153chr6:17646298chr6:15524900ENST00000262077-1422657_6875731476.0Zinc fingerRanBP2-type 1
HgeneNUP153chr6:17646298chr6:15524900ENST00000262077-1422722_7515731476.0Zinc fingerRanBP2-type 2
HgeneNUP153chr6:17646298chr6:15524900ENST00000262077-1422793_8225731476.0Zinc fingerRanBP2-type 3
HgeneNUP153chr6:17646298chr6:15524900ENST00000262077-1422851_8805731476.0Zinc fingerRanBP2-type 4
TgeneDTNBP1chr6:17646298chr6:15524900ENST000003389507988_181222304.0Coiled coilOntology_term=ECO:0000255
TgeneDTNBP1chr6:17646298chr6:15524900ENST0000034453771088_181222352.0Coiled coilOntology_term=ECO:0000255
TgeneDTNBP1chr6:17646298chr6:15524900ENST0000033895079173_331222304.0RegionNote=Dysbindin
TgeneDTNBP1chr6:17646298chr6:15524900ENST00000344537710173_331222352.0RegionNote=Dysbindin


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Fusion Gene Sequence for NUP153-DTNBP1


check button For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. To have fusion amino acid sequence, we ran ORFfinder and chose the longest ORF among the all predicted ones.
>60972_60972_1_NUP153-DTNBP1_NUP153_chr6_17646298_ENST00000262077_DTNBP1_chr6_15524900_ENST00000338950_length(transcript)=2827nt_BP=1720nt
ATGGCCTCGGGAGCCGGAGGAGTCGGAGGGGGCGGTGGCGGCAAGATCCGGACGCGGCGTTGCCACCAGGGGCCAATTAAGCCTTACCAG
CAGGGGCGACAACAGCATCAGGGCATTCTTAGCAGGGTTACAGAATCTGTTAAGAATATTGTGCCAGGGTGGCTACAAAGATACTTCAAC
AAGAATGAAGATGTATGCAGCTGTTCAACAGACACAAGCGAGGTTCCACGCTGGCCAGAAAATAAAGAGGACCATCTGGTATATGCCGAT
GAGGAGAGCTCTAATATTACTGATGGGAGAATCACACCTGAGCCAGCAGTCAGTAATACAGAAGAACCTTCAACAACTAGTACTGCTTCA
AATTATCCAGATGTGTTAACAAGGCCTTCTCTTCATCGGAGCCATCTGAATTTTTCCATGTTGGAATCCCCTGCATTACACTGTCAGCCA
TCTACATCCTCGGCATTCCCAATTGGCAGTTCGGGATTTTCCCTTGTAAAGGAAATTAAAGATTCTACCTCTCAGCATGATGATGATAAC
ATCTCAACTACCAGTGGTTTTTCTTCAAGAGCTTCTGATAAAGATATAACTGTTTCAAAGAACACTTCATTGCCACCTCTGTGGTCCCCA
GAAGCTGAACGTTCTCACTCACTCTCACAGCACACTGCCACCAGCTCAAAAAAACCAGCATTCAACTTGTCTGCCTTTGGAACACTTTCC
CCTTCACTTGGGAATTCTTCAATCCTTAAAACCAGTCAGCTTGGAGATTCTCCTTTTTATCCTGGAAAAACAACATACGGTGGGGCAGCA
GCTGCTGTAAGACAGTCTAAACTACGAAATACACCTTATCAGGCACCAGTTAGAAGACAAATGAAAGCTAAGCAACTCAGTGCACAATCT
TACGGTGTGACCAGTTCAACAGCTCGGCGAATATTGCAGTCTTTAGAGAAGATGTCAAGCCCTTTAGCGGATGCAAAAAGAATTCCATCC
ATTGTTTCTTCTCCTCTGAATTCTCCTCTTGATAGGAGTGGGATAGATATCACAGATTTTCAGGCCAAAAGAGAAAAGGTGGATTCTCAA
TATCCTCCTGTTCAGAGACTTATGACCCCAAAGCCAGTTTCCATAGCAACAAATCGAAGTGTTTATTTTAAACCATCTCTGACTCCTTCT
GGTGAATTCAGGAAGACTAATCAAAGAATAGATAACAAGTGCAGTACTGGATATGAAAAAAATATGACACCCGGACAAAATAGAGAACAA
CGAGAAAGTGGCTTTTCATATCCAAATTTCAGTTTGCCTGCAGCCAATGGTTTATCTTCTGGAGTAGGTGGTGGAGGTGGCAAGATGAGA
CGAGAAAGAACACGCTTTGTTGCTTCTAAACCTCTGGAGGAGGAGGAAATGGAAGTTCCAGTATTACCGAAAATCTCTCTACCGATCACC
AGTTCTTCACTGCCTACCTTTAATTTTAGTTCCCCTGAGATCACAACTTCCTCTCCATCACCCATCAATTCGTCTCAAGCATTAACAAAC
AAGGTACAAATGACCTCTCCGAGCAGCACTGGCAGTCCCATGTTTAAATTTTCATCTCCAATCGTAAAATCTACTGAGGCAAATGTACTA
CCTCCATCATCTATTGGATTTACATTTAGTGTGCCTGTTGCAAAAACAGCAGAACTTTCTGGTTCTAGTAGTACTTTAGAACCAATTATA
AGTAGTTCAGAGCCCATAGGCAGCATGTCATCCATGGAAGTGAACGTGGACATGCTGGAGCAGATGGACCTGATGGACATATCGGACCAG
GAGGCCCTGGACGTCTTCCTGAACTCTGGAGGAGAAGAGAACACTGTGCTGTCCCCCGCCTTAGGTAGGGTTGACAAACTTGCATTAGCT
GAACCAGGGCAGTATCGATGCCACTCCCCTCCAAAGGTGAGACGTGAGAACCATCTGCCAGTCACTTACGCATAAACCCCCAAGCTCACA
GCCAGCTCCTGGCTCCCTAACCCCACGGTTCCACACGGCTGTGTGGCAGCTGCAACAGTGGTGTGGTTCCGTCATGAATTCTTCTCAAAG
ATTTGACATGCTCCACTCCGGTAACTTTGGTGAGTTGAGAGCTTTCTTGTTTGTTTTCCCTCCTTTACCACCCAGAAATCCATTTGAGTC
TGCTCCTTGTGGTTAAGGACTGGCGTTTGCAGGGAGGTGCGGACTCTCCTGCGGGGCTCACGGGAAACTCTTCCCTCTTCGTGCGACAGG
CATTTAGGGGCGTGCCTGCCATGGGCAAAGCCATGGTGTGTGTTCAGCTCTTGGCCTGTGTTGTAAACTTAGTTGCACTTCAGTTCCTTT
CATCCCTTCACAAAATTTTGTTTCACATTCATGCAGCAAATATGGGCTGAGGTGCCAGACCTGTACCTGGGCTTGGTGCGTTTCAAATTT
CAGACCAGTTCTTTGGGCTGGGTCAAGGCAAAGCTCAGTCGTCCCAGCAGCACCTCAGCCATCTGTAGAAGGTTCTACCATTACCACGGT
TTCAGCTTCCTCTAAACTTCTCACCCGCTTCTCCTGGCAATCTGTCAGAACGGTGTCATCCTGGGGAAGAGAAGGAGCTTGGGTGCATTT
GCCCTCATCCTGAGAAGGCCAGAATACTGGAGACCAGCGTGAACCCTCACCCAGAGTCAGGGGAAGATTTAGAAACAGTGACACCTGCAT
ATAGAATTTTGATTCCTTGAAGAGCCTATTTAGTTCCATAAAATTGGAGAACTGCTGAAGGTCAGTAATTCCGACTTTCTCAGCAGTGGT

>60972_60972_1_NUP153-DTNBP1_NUP153_chr6_17646298_ENST00000262077_DTNBP1_chr6_15524900_ENST00000338950_length(amino acids)=654AA_BP=571
MASGAGGVGGGGGGKIRTRRCHQGPIKPYQQGRQQHQGILSRVTESVKNIVPGWLQRYFNKNEDVCSCSTDTSEVPRWPENKEDHLVYAD
EESSNITDGRITPEPAVSNTEEPSTTSTASNYPDVLTRPSLHRSHLNFSMLESPALHCQPSTSSAFPIGSSGFSLVKEIKDSTSQHDDDN
ISTTSGFSSRASDKDITVSKNTSLPPLWSPEAERSHSLSQHTATSSKKPAFNLSAFGTLSPSLGNSSILKTSQLGDSPFYPGKTTYGGAA
AAVRQSKLRNTPYQAPVRRQMKAKQLSAQSYGVTSSTARRILQSLEKMSSPLADAKRIPSIVSSPLNSPLDRSGIDITDFQAKREKVDSQ
YPPVQRLMTPKPVSIATNRSVYFKPSLTPSGEFRKTNQRIDNKCSTGYEKNMTPGQNREQRESGFSYPNFSLPAANGLSSGVGGGGGKMR
RERTRFVASKPLEEEEMEVPVLPKISLPITSSSLPTFNFSSPEITTSSPSPINSSQALTNKVQMTSPSSTGSPMFKFSSPIVKSTEANVL
PPSSIGFTFSVPVAKTAELSGSSSTLEPIISSSEPIGSMSSMEVNVDMLEQMDLMDISDQEALDVFLNSGGEENTVLSPALGRVDKLALA

--------------------------------------------------------------
>60972_60972_2_NUP153-DTNBP1_NUP153_chr6_17646298_ENST00000262077_DTNBP1_chr6_15524900_ENST00000344537_length(transcript)=2283nt_BP=1720nt
ATGGCCTCGGGAGCCGGAGGAGTCGGAGGGGGCGGTGGCGGCAAGATCCGGACGCGGCGTTGCCACCAGGGGCCAATTAAGCCTTACCAG
CAGGGGCGACAACAGCATCAGGGCATTCTTAGCAGGGTTACAGAATCTGTTAAGAATATTGTGCCAGGGTGGCTACAAAGATACTTCAAC
AAGAATGAAGATGTATGCAGCTGTTCAACAGACACAAGCGAGGTTCCACGCTGGCCAGAAAATAAAGAGGACCATCTGGTATATGCCGAT
GAGGAGAGCTCTAATATTACTGATGGGAGAATCACACCTGAGCCAGCAGTCAGTAATACAGAAGAACCTTCAACAACTAGTACTGCTTCA
AATTATCCAGATGTGTTAACAAGGCCTTCTCTTCATCGGAGCCATCTGAATTTTTCCATGTTGGAATCCCCTGCATTACACTGTCAGCCA
TCTACATCCTCGGCATTCCCAATTGGCAGTTCGGGATTTTCCCTTGTAAAGGAAATTAAAGATTCTACCTCTCAGCATGATGATGATAAC
ATCTCAACTACCAGTGGTTTTTCTTCAAGAGCTTCTGATAAAGATATAACTGTTTCAAAGAACACTTCATTGCCACCTCTGTGGTCCCCA
GAAGCTGAACGTTCTCACTCACTCTCACAGCACACTGCCACCAGCTCAAAAAAACCAGCATTCAACTTGTCTGCCTTTGGAACACTTTCC
CCTTCACTTGGGAATTCTTCAATCCTTAAAACCAGTCAGCTTGGAGATTCTCCTTTTTATCCTGGAAAAACAACATACGGTGGGGCAGCA
GCTGCTGTAAGACAGTCTAAACTACGAAATACACCTTATCAGGCACCAGTTAGAAGACAAATGAAAGCTAAGCAACTCAGTGCACAATCT
TACGGTGTGACCAGTTCAACAGCTCGGCGAATATTGCAGTCTTTAGAGAAGATGTCAAGCCCTTTAGCGGATGCAAAAAGAATTCCATCC
ATTGTTTCTTCTCCTCTGAATTCTCCTCTTGATAGGAGTGGGATAGATATCACAGATTTTCAGGCCAAAAGAGAAAAGGTGGATTCTCAA
TATCCTCCTGTTCAGAGACTTATGACCCCAAAGCCAGTTTCCATAGCAACAAATCGAAGTGTTTATTTTAAACCATCTCTGACTCCTTCT
GGTGAATTCAGGAAGACTAATCAAAGAATAGATAACAAGTGCAGTACTGGATATGAAAAAAATATGACACCCGGACAAAATAGAGAACAA
CGAGAAAGTGGCTTTTCATATCCAAATTTCAGTTTGCCTGCAGCCAATGGTTTATCTTCTGGAGTAGGTGGTGGAGGTGGCAAGATGAGA
CGAGAAAGAACACGCTTTGTTGCTTCTAAACCTCTGGAGGAGGAGGAAATGGAAGTTCCAGTATTACCGAAAATCTCTCTACCGATCACC
AGTTCTTCACTGCCTACCTTTAATTTTAGTTCCCCTGAGATCACAACTTCCTCTCCATCACCCATCAATTCGTCTCAAGCATTAACAAAC
AAGGTACAAATGACCTCTCCGAGCAGCACTGGCAGTCCCATGTTTAAATTTTCATCTCCAATCGTAAAATCTACTGAGGCAAATGTACTA
CCTCCATCATCTATTGGATTTACATTTAGTGTGCCTGTTGCAAAAACAGCAGAACTTTCTGGTTCTAGTAGTACTTTAGAACCAATTATA
AGTAGTTCAGAGCCCATAGGCAGCATGTCATCCATGGAAGTGAACGTGGACATGCTGGAGCAGATGGACCTGATGGACATATCGGACCAG
GAGGCCCTGGACGTCTTCCTGAACTCTGGAGGAGAAGAGAACACTGTGCTGTCCCCCGCCTTAGGGCCTGAATCCAGTACCTGTCAGAAT
GAGATTACCCTCCAGGTTCCAAATCCCTCAGAATTAAGAGCCAAGCCACCTTCTTCTTCCTCCACCTGCACCGACTCGGCCACCCGGGAC
ATCAGTGAGGGTGGGGAGTCCCCCGTTGTTCAGTCCGATGAGGAGGAAGTTCAGGTGGACACTGCCCTGGCCACATCACACACTGACAGA
GAGGCCACTCCGGATGGTGGTGAGGACAGCGACTCTTAAATTGGGACATGGGCGTTGTCTGGCCACACTGGAATCCAGTTTTGGCTGTAT
GCGGAATTCCACCTGGAAAGCCAGGTTGTTTTATAGAGGTTCTTGATTTTTACATAATTGCCAATAATGTGTGAGAAACTTAAAGAACAG

>60972_60972_2_NUP153-DTNBP1_NUP153_chr6_17646298_ENST00000262077_DTNBP1_chr6_15524900_ENST00000344537_length(amino acids)=702AA_BP=571
MASGAGGVGGGGGGKIRTRRCHQGPIKPYQQGRQQHQGILSRVTESVKNIVPGWLQRYFNKNEDVCSCSTDTSEVPRWPENKEDHLVYAD
EESSNITDGRITPEPAVSNTEEPSTTSTASNYPDVLTRPSLHRSHLNFSMLESPALHCQPSTSSAFPIGSSGFSLVKEIKDSTSQHDDDN
ISTTSGFSSRASDKDITVSKNTSLPPLWSPEAERSHSLSQHTATSSKKPAFNLSAFGTLSPSLGNSSILKTSQLGDSPFYPGKTTYGGAA
AAVRQSKLRNTPYQAPVRRQMKAKQLSAQSYGVTSSTARRILQSLEKMSSPLADAKRIPSIVSSPLNSPLDRSGIDITDFQAKREKVDSQ
YPPVQRLMTPKPVSIATNRSVYFKPSLTPSGEFRKTNQRIDNKCSTGYEKNMTPGQNREQRESGFSYPNFSLPAANGLSSGVGGGGGKMR
RERTRFVASKPLEEEEMEVPVLPKISLPITSSSLPTFNFSSPEITTSSPSPINSSQALTNKVQMTSPSSTGSPMFKFSSPIVKSTEANVL
PPSSIGFTFSVPVAKTAELSGSSSTLEPIISSSEPIGSMSSMEVNVDMLEQMDLMDISDQEALDVFLNSGGEENTVLSPALGPESSTCQN

--------------------------------------------------------------
>60972_60972_3_NUP153-DTNBP1_NUP153_chr6_17646298_ENST00000262077_DTNBP1_chr6_15524900_ENST00000355917_length(transcript)=2274nt_BP=1720nt
ATGGCCTCGGGAGCCGGAGGAGTCGGAGGGGGCGGTGGCGGCAAGATCCGGACGCGGCGTTGCCACCAGGGGCCAATTAAGCCTTACCAG
CAGGGGCGACAACAGCATCAGGGCATTCTTAGCAGGGTTACAGAATCTGTTAAGAATATTGTGCCAGGGTGGCTACAAAGATACTTCAAC
AAGAATGAAGATGTATGCAGCTGTTCAACAGACACAAGCGAGGTTCCACGCTGGCCAGAAAATAAAGAGGACCATCTGGTATATGCCGAT
GAGGAGAGCTCTAATATTACTGATGGGAGAATCACACCTGAGCCAGCAGTCAGTAATACAGAAGAACCTTCAACAACTAGTACTGCTTCA
AATTATCCAGATGTGTTAACAAGGCCTTCTCTTCATCGGAGCCATCTGAATTTTTCCATGTTGGAATCCCCTGCATTACACTGTCAGCCA
TCTACATCCTCGGCATTCCCAATTGGCAGTTCGGGATTTTCCCTTGTAAAGGAAATTAAAGATTCTACCTCTCAGCATGATGATGATAAC
ATCTCAACTACCAGTGGTTTTTCTTCAAGAGCTTCTGATAAAGATATAACTGTTTCAAAGAACACTTCATTGCCACCTCTGTGGTCCCCA
GAAGCTGAACGTTCTCACTCACTCTCACAGCACACTGCCACCAGCTCAAAAAAACCAGCATTCAACTTGTCTGCCTTTGGAACACTTTCC
CCTTCACTTGGGAATTCTTCAATCCTTAAAACCAGTCAGCTTGGAGATTCTCCTTTTTATCCTGGAAAAACAACATACGGTGGGGCAGCA
GCTGCTGTAAGACAGTCTAAACTACGAAATACACCTTATCAGGCACCAGTTAGAAGACAAATGAAAGCTAAGCAACTCAGTGCACAATCT
TACGGTGTGACCAGTTCAACAGCTCGGCGAATATTGCAGTCTTTAGAGAAGATGTCAAGCCCTTTAGCGGATGCAAAAAGAATTCCATCC
ATTGTTTCTTCTCCTCTGAATTCTCCTCTTGATAGGAGTGGGATAGATATCACAGATTTTCAGGCCAAAAGAGAAAAGGTGGATTCTCAA
TATCCTCCTGTTCAGAGACTTATGACCCCAAAGCCAGTTTCCATAGCAACAAATCGAAGTGTTTATTTTAAACCATCTCTGACTCCTTCT
GGTGAATTCAGGAAGACTAATCAAAGAATAGATAACAAGTGCAGTACTGGATATGAAAAAAATATGACACCCGGACAAAATAGAGAACAA
CGAGAAAGTGGCTTTTCATATCCAAATTTCAGTTTGCCTGCAGCCAATGGTTTATCTTCTGGAGTAGGTGGTGGAGGTGGCAAGATGAGA
CGAGAAAGAACACGCTTTGTTGCTTCTAAACCTCTGGAGGAGGAGGAAATGGAAGTTCCAGTATTACCGAAAATCTCTCTACCGATCACC
AGTTCTTCACTGCCTACCTTTAATTTTAGTTCCCCTGAGATCACAACTTCCTCTCCATCACCCATCAATTCGTCTCAAGCATTAACAAAC
AAGGTACAAATGACCTCTCCGAGCAGCACTGGCAGTCCCATGTTTAAATTTTCATCTCCAATCGTAAAATCTACTGAGGCAAATGTACTA
CCTCCATCATCTATTGGATTTACATTTAGTGTGCCTGTTGCAAAAACAGCAGAACTTTCTGGTTCTAGTAGTACTTTAGAACCAATTATA
AGTAGTTCAGAGCCCATAGGCAGCATGTCATCCATGGAAGTGAACGTGGACATGCTGGAGCAGATGGACCTGATGGACATATCGGACCAG
GAGGCCCTGGACGTCTTCCTGAACTCTGGAGGAGAAGAGAACACTGTGCTGTCCCCCGCCTTAGGGCCTGAATCCAGTACCTGTCAGAAT
GAGATTACCCTCCAGGTTCCAAATCCCTCAGAATTAAGAGCCAAGCCACCTTCTTCTTCCTCCACCTGCACCGACTCGGCCACCCGGGAC
ATCAGTGAGGGTGGGGAGTCCCCCGTTGTTCAGTCCGATGAGGAGGAAGTTCAGGTGGACACTGCCCTGGCCACATCACACACTGACAGA
GAGGCCACTCCGGATGGTGGTGAGGACAGCGACTCTTAAATTGGGACATGGGCGTTGTCTGGCCACACTGGAATCCAGTTTTGGCTGTAT
GCGGAATTCCACCTGGAAAGCCAGGTTGTTTTATAGAGGTTCTTGATTTTTACATAATTGCCAATAATGTGTGAGAAACTTAAAGAACAG

>60972_60972_3_NUP153-DTNBP1_NUP153_chr6_17646298_ENST00000262077_DTNBP1_chr6_15524900_ENST00000355917_length(amino acids)=702AA_BP=571
MASGAGGVGGGGGGKIRTRRCHQGPIKPYQQGRQQHQGILSRVTESVKNIVPGWLQRYFNKNEDVCSCSTDTSEVPRWPENKEDHLVYAD
EESSNITDGRITPEPAVSNTEEPSTTSTASNYPDVLTRPSLHRSHLNFSMLESPALHCQPSTSSAFPIGSSGFSLVKEIKDSTSQHDDDN
ISTTSGFSSRASDKDITVSKNTSLPPLWSPEAERSHSLSQHTATSSKKPAFNLSAFGTLSPSLGNSSILKTSQLGDSPFYPGKTTYGGAA
AAVRQSKLRNTPYQAPVRRQMKAKQLSAQSYGVTSSTARRILQSLEKMSSPLADAKRIPSIVSSPLNSPLDRSGIDITDFQAKREKVDSQ
YPPVQRLMTPKPVSIATNRSVYFKPSLTPSGEFRKTNQRIDNKCSTGYEKNMTPGQNREQRESGFSYPNFSLPAANGLSSGVGGGGGKMR
RERTRFVASKPLEEEEMEVPVLPKISLPITSSSLPTFNFSSPEITTSSPSPINSSQALTNKVQMTSPSSTGSPMFKFSSPIVKSTEANVL
PPSSIGFTFSVPVAKTAELSGSSSTLEPIISSSEPIGSMSSMEVNVDMLEQMDLMDISDQEALDVFLNSGGEENTVLSPALGPESSTCQN

--------------------------------------------------------------
>60972_60972_4_NUP153-DTNBP1_NUP153_chr6_17646298_ENST00000262077_DTNBP1_chr6_15524900_ENST00000462989_length(transcript)=2277nt_BP=1720nt
ATGGCCTCGGGAGCCGGAGGAGTCGGAGGGGGCGGTGGCGGCAAGATCCGGACGCGGCGTTGCCACCAGGGGCCAATTAAGCCTTACCAG
CAGGGGCGACAACAGCATCAGGGCATTCTTAGCAGGGTTACAGAATCTGTTAAGAATATTGTGCCAGGGTGGCTACAAAGATACTTCAAC
AAGAATGAAGATGTATGCAGCTGTTCAACAGACACAAGCGAGGTTCCACGCTGGCCAGAAAATAAAGAGGACCATCTGGTATATGCCGAT
GAGGAGAGCTCTAATATTACTGATGGGAGAATCACACCTGAGCCAGCAGTCAGTAATACAGAAGAACCTTCAACAACTAGTACTGCTTCA
AATTATCCAGATGTGTTAACAAGGCCTTCTCTTCATCGGAGCCATCTGAATTTTTCCATGTTGGAATCCCCTGCATTACACTGTCAGCCA
TCTACATCCTCGGCATTCCCAATTGGCAGTTCGGGATTTTCCCTTGTAAAGGAAATTAAAGATTCTACCTCTCAGCATGATGATGATAAC
ATCTCAACTACCAGTGGTTTTTCTTCAAGAGCTTCTGATAAAGATATAACTGTTTCAAAGAACACTTCATTGCCACCTCTGTGGTCCCCA
GAAGCTGAACGTTCTCACTCACTCTCACAGCACACTGCCACCAGCTCAAAAAAACCAGCATTCAACTTGTCTGCCTTTGGAACACTTTCC
CCTTCACTTGGGAATTCTTCAATCCTTAAAACCAGTCAGCTTGGAGATTCTCCTTTTTATCCTGGAAAAACAACATACGGTGGGGCAGCA
GCTGCTGTAAGACAGTCTAAACTACGAAATACACCTTATCAGGCACCAGTTAGAAGACAAATGAAAGCTAAGCAACTCAGTGCACAATCT
TACGGTGTGACCAGTTCAACAGCTCGGCGAATATTGCAGTCTTTAGAGAAGATGTCAAGCCCTTTAGCGGATGCAAAAAGAATTCCATCC
ATTGTTTCTTCTCCTCTGAATTCTCCTCTTGATAGGAGTGGGATAGATATCACAGATTTTCAGGCCAAAAGAGAAAAGGTGGATTCTCAA
TATCCTCCTGTTCAGAGACTTATGACCCCAAAGCCAGTTTCCATAGCAACAAATCGAAGTGTTTATTTTAAACCATCTCTGACTCCTTCT
GGTGAATTCAGGAAGACTAATCAAAGAATAGATAACAAGTGCAGTACTGGATATGAAAAAAATATGACACCCGGACAAAATAGAGAACAA
CGAGAAAGTGGCTTTTCATATCCAAATTTCAGTTTGCCTGCAGCCAATGGTTTATCTTCTGGAGTAGGTGGTGGAGGTGGCAAGATGAGA
CGAGAAAGAACACGCTTTGTTGCTTCTAAACCTCTGGAGGAGGAGGAAATGGAAGTTCCAGTATTACCGAAAATCTCTCTACCGATCACC
AGTTCTTCACTGCCTACCTTTAATTTTAGTTCCCCTGAGATCACAACTTCCTCTCCATCACCCATCAATTCGTCTCAAGCATTAACAAAC
AAGGTACAAATGACCTCTCCGAGCAGCACTGGCAGTCCCATGTTTAAATTTTCATCTCCAATCGTAAAATCTACTGAGGCAAATGTACTA
CCTCCATCATCTATTGGATTTACATTTAGTGTGCCTGTTGCAAAAACAGCAGAACTTTCTGGTTCTAGTAGTACTTTAGAACCAATTATA
AGTAGTTCAGAGCCCATAGGCAGCATGTCATCCATGGAAGTGAACGTGGACATGCTGGAGCAGATGGACCTGATGGACATATCGGACCAG
GAGGCCCTGGACGTCTTCCTGAACTCTGGAGGAGAAGAGAACACTGTGCTGTCCCCCGCCTTAGGGCCTGAATCCAGTACCTGTCAGAAT
GAGATTACCCTCCAGGTTCCAAATCCCTCAGAATTAAGAGCCAAGCCACCTTCTTCTTCCTCCACCTGCACCGACTCGGCCACCCGGGAC
ATCAGTGAGGGTGGGGAGTCCCCCGTTGTTCAGTCCGATGAGGAGGAAGTTCAGGTGGACACTGCCCTGGCCACATCACACACTGACAGA
GAGGCCACTCCGGATGGTGGTGAGGACAGCGACTCTTAAATTGGGACATGGGCGTTGTCTGGCCACACTGGAATCCAGTTTTGGCTGTAT
GCGGAATTCCACCTGGAAAGCCAGGTTGTTTTATAGAGGTTCTTGATTTTTACATAATTGCCAATAATGTGTGAGAAACTTAAAGAACAG

>60972_60972_4_NUP153-DTNBP1_NUP153_chr6_17646298_ENST00000262077_DTNBP1_chr6_15524900_ENST00000462989_length(amino acids)=702AA_BP=571
MASGAGGVGGGGGGKIRTRRCHQGPIKPYQQGRQQHQGILSRVTESVKNIVPGWLQRYFNKNEDVCSCSTDTSEVPRWPENKEDHLVYAD
EESSNITDGRITPEPAVSNTEEPSTTSTASNYPDVLTRPSLHRSHLNFSMLESPALHCQPSTSSAFPIGSSGFSLVKEIKDSTSQHDDDN
ISTTSGFSSRASDKDITVSKNTSLPPLWSPEAERSHSLSQHTATSSKKPAFNLSAFGTLSPSLGNSSILKTSQLGDSPFYPGKTTYGGAA
AAVRQSKLRNTPYQAPVRRQMKAKQLSAQSYGVTSSTARRILQSLEKMSSPLADAKRIPSIVSSPLNSPLDRSGIDITDFQAKREKVDSQ
YPPVQRLMTPKPVSIATNRSVYFKPSLTPSGEFRKTNQRIDNKCSTGYEKNMTPGQNREQRESGFSYPNFSLPAANGLSSGVGGGGGKMR
RERTRFVASKPLEEEEMEVPVLPKISLPITSSSLPTFNFSSPEITTSSPSPINSSQALTNKVQMTSPSSTGSPMFKFSSPIVKSTEANVL
PPSSIGFTFSVPVAKTAELSGSSSTLEPIISSSEPIGSMSSMEVNVDMLEQMDLMDISDQEALDVFLNSGGEENTVLSPALGPESSTCQN

--------------------------------------------------------------
>60972_60972_5_NUP153-DTNBP1_NUP153_chr6_17646298_ENST00000537253_DTNBP1_chr6_15524900_ENST00000338950_length(transcript)=2958nt_BP=1851nt
TTACCCGCCCCGGAGCGGGAAGCGGCGGAGGCTCCGCCATGGCCTCGGGAGCCGGAGGAGTCGGAGGGGGCGGTGGCGGCAAGATCCGGA
CGCGGCGTTGCCACCAGGGGCCAATTAAGCCTTACCAGCAGGGGCGACAACAGCATCAGGGCATTCTTAGCAGGGTTACAGAATCTGTTA
AGAATATTGTGCCAGGGTGGCTACAAAGATACTTCAACAAGAATGAAGATGTATGCAGCTGTTCAACAGACACAAGCGAGGTTCCACGCT
GGCCAGAAAATAAAGAGGACCATCTGGTATATGCCGATGAGGAGAGCTCTAATATTACTGATGGGAGAATCACACCTGAGCCAGCAGTCA
GTAATACAGAAGAACCTTCAACAACTAGTACTGCTTCAAATTATCCAGATGTGTTAACAAGGCCTTCTCTTCATCGGAGCCATCTGAATT
TTTCCATGTTGGAATCCCCTGCATTACACTGTCAGCCATCTACATCCTCGGCATTCCCAATTGGCAGTTCGGGATTTTCCCTTGTAAAGG
AAATTAAAGATTCTACCTCTCAGCATGATGATGATAACATCTCAACTACCAGTGGTTTTTCTTCAAGAGCTTCTGATAAAGATATAACTG
TTTCAAAGAACACTTCATTGCCACCTCTGTGGTCCCCAGAAGCTGAACGTTCTCACTCACTCTCACAGCACACTGCCACCAGCTCAAAAA
AACCAGCATTCAACTTGTCTGCCTTTGGAACACTTTCCCCTTCACTTGGGAATTCTTCAATCCTTAAAACCAGTCAGCTTGGAGATTCTC
CTTTTTATCCTGGAAAAACAACATACGGTGGGGCAGCAGCTGCTGTAAGACAGTCTAAACTACGAAATACACCTTATCAGGCACCAGTTA
GAAGACAAATGAAAGCTAAGCAACTCAGTGCACAATCTTACGGTGTGACCAGTTCAACAGCTCGGCGAATATTGCAGTCTTTAGAGAAGA
TGTCAAGCCCTTTAGCGGATGCAAAAAGAATTCCATCCATTGTTTCTTCTCCTCTGAATTCTCCTCTTGATAGGAGTGGGATAGATATCA
CAGATTTTCAGGCCAAAAGAGAAAAGGTGGATTCTCAATATCCTCCTGTTCAGAGACTTATGACCCCAAAGCCAGTTTCCATAGCAACAA
ATCGAAGTGTTTATTTTAAACCATCTCTGACTCCTTCTGGTGAATTCAGGAAGACTAATCAAAGAATAGATAACAAGTGCAGTACTGGAT
ATGAAAAAAATATGACACCCGGACAAAATAGAGAACAACGAGAAAGTGGCTTTTCATATCCAAATTTCAGTTTGCCTGCAGCCAATGGTT
TATCTTCTGGAGTAGGTGGTGGAGGTGGCAAGATGAGACGAGAAAGAACACGCTTTGTTGCTTCTAAACCTCTGGAGGAGGAGAGACAAG
GTCTCACCGTATTGCCCAAGCTGATCTCGAGCTCCTGCGCTCAAGCGATCATCCCATCTTGGCCTCTCAAAGTGCTGAGATTACAGGAAA
TGGAAGTTCCAGTATTACCGAAAATCTCTCTACCGATCACCAGTTCTTCACTGCCTACCTTTAATTTTAGTTCCCCTGAGATCACAACTT
CCTCTCCATCACCCATCAATTCGTCTCAAGCATTAACAAACAAGGTACAAATGACCTCTCCGAGCAGCACTGGCAGTCCCATGTTTAAAT
TTTCATCTCCAATCGTAAAATCTACTGAGGCAAATGTACTACCTCCATCATCTATTGGATTTACATTTAGTGTGCCTGTTGCAAAAACAG
CAGAACTTTCTGGTTCTAGTAGTACTTTAGAACCAATTATAAGTAGTTCAGAGCCCATAGGCAGCATGTCATCCATGGAAGTGAACGTGG
ACATGCTGGAGCAGATGGACCTGATGGACATATCGGACCAGGAGGCCCTGGACGTCTTCCTGAACTCTGGAGGAGAAGAGAACACTGTGC
TGTCCCCCGCCTTAGGTAGGGTTGACAAACTTGCATTAGCTGAACCAGGGCAGTATCGATGCCACTCCCCTCCAAAGGTGAGACGTGAGA
ACCATCTGCCAGTCACTTACGCATAAACCCCCAAGCTCACAGCCAGCTCCTGGCTCCCTAACCCCACGGTTCCACACGGCTGTGTGGCAG
CTGCAACAGTGGTGTGGTTCCGTCATGAATTCTTCTCAAAGATTTGACATGCTCCACTCCGGTAACTTTGGTGAGTTGAGAGCTTTCTTG
TTTGTTTTCCCTCCTTTACCACCCAGAAATCCATTTGAGTCTGCTCCTTGTGGTTAAGGACTGGCGTTTGCAGGGAGGTGCGGACTCTCC
TGCGGGGCTCACGGGAAACTCTTCCCTCTTCGTGCGACAGGCATTTAGGGGCGTGCCTGCCATGGGCAAAGCCATGGTGTGTGTTCAGCT
CTTGGCCTGTGTTGTAAACTTAGTTGCACTTCAGTTCCTTTCATCCCTTCACAAAATTTTGTTTCACATTCATGCAGCAAATATGGGCTG
AGGTGCCAGACCTGTACCTGGGCTTGGTGCGTTTCAAATTTCAGACCAGTTCTTTGGGCTGGGTCAAGGCAAAGCTCAGTCGTCCCAGCA
GCACCTCAGCCATCTGTAGAAGGTTCTACCATTACCACGGTTTCAGCTTCCTCTAAACTTCTCACCCGCTTCTCCTGGCAATCTGTCAGA
ACGGTGTCATCCTGGGGAAGAGAAGGAGCTTGGGTGCATTTGCCCTCATCCTGAGAAGGCCAGAATACTGGAGACCAGCGTGAACCCTCA
CCCAGAGTCAGGGGAAGATTTAGAAACAGTGACACCTGCATATAGAATTTTGATTCCTTGAAGAGCCTATTTAGTTCCATAAAATTGGAG

>60972_60972_5_NUP153-DTNBP1_NUP153_chr6_17646298_ENST00000537253_DTNBP1_chr6_15524900_ENST00000338950_length(amino acids)=685AA_BP=466
MASGAGGVGGGGGGKIRTRRCHQGPIKPYQQGRQQHQGILSRVTESVKNIVPGWLQRYFNKNEDVCSCSTDTSEVPRWPENKEDHLVYAD
EESSNITDGRITPEPAVSNTEEPSTTSTASNYPDVLTRPSLHRSHLNFSMLESPALHCQPSTSSAFPIGSSGFSLVKEIKDSTSQHDDDN
ISTTSGFSSRASDKDITVSKNTSLPPLWSPEAERSHSLSQHTATSSKKPAFNLSAFGTLSPSLGNSSILKTSQLGDSPFYPGKTTYGGAA
AAVRQSKLRNTPYQAPVRRQMKAKQLSAQSYGVTSSTARRILQSLEKMSSPLADAKRIPSIVSSPLNSPLDRSGIDITDFQAKREKVDSQ
YPPVQRLMTPKPVSIATNRSVYFKPSLTPSGEFRKTNQRIDNKCSTGYEKNMTPGQNREQRESGFSYPNFSLPAANGLSSGVGGGGGKMR
RERTRFVASKPLEEERQGLTVLPKLISSSCAQAIIPSWPLKVLRLQEMEVPVLPKISLPITSSSLPTFNFSSPEITTSSPSPINSSQALT
NKVQMTSPSSTGSPMFKFSSPIVKSTEANVLPPSSIGFTFSVPVAKTAELSGSSSTLEPIISSSEPIGSMSSMEVNVDMLEQMDLMDISD

--------------------------------------------------------------
>60972_60972_6_NUP153-DTNBP1_NUP153_chr6_17646298_ENST00000537253_DTNBP1_chr6_15524900_ENST00000344537_length(transcript)=2414nt_BP=1851nt
TTACCCGCCCCGGAGCGGGAAGCGGCGGAGGCTCCGCCATGGCCTCGGGAGCCGGAGGAGTCGGAGGGGGCGGTGGCGGCAAGATCCGGA
CGCGGCGTTGCCACCAGGGGCCAATTAAGCCTTACCAGCAGGGGCGACAACAGCATCAGGGCATTCTTAGCAGGGTTACAGAATCTGTTA
AGAATATTGTGCCAGGGTGGCTACAAAGATACTTCAACAAGAATGAAGATGTATGCAGCTGTTCAACAGACACAAGCGAGGTTCCACGCT
GGCCAGAAAATAAAGAGGACCATCTGGTATATGCCGATGAGGAGAGCTCTAATATTACTGATGGGAGAATCACACCTGAGCCAGCAGTCA
GTAATACAGAAGAACCTTCAACAACTAGTACTGCTTCAAATTATCCAGATGTGTTAACAAGGCCTTCTCTTCATCGGAGCCATCTGAATT
TTTCCATGTTGGAATCCCCTGCATTACACTGTCAGCCATCTACATCCTCGGCATTCCCAATTGGCAGTTCGGGATTTTCCCTTGTAAAGG
AAATTAAAGATTCTACCTCTCAGCATGATGATGATAACATCTCAACTACCAGTGGTTTTTCTTCAAGAGCTTCTGATAAAGATATAACTG
TTTCAAAGAACACTTCATTGCCACCTCTGTGGTCCCCAGAAGCTGAACGTTCTCACTCACTCTCACAGCACACTGCCACCAGCTCAAAAA
AACCAGCATTCAACTTGTCTGCCTTTGGAACACTTTCCCCTTCACTTGGGAATTCTTCAATCCTTAAAACCAGTCAGCTTGGAGATTCTC
CTTTTTATCCTGGAAAAACAACATACGGTGGGGCAGCAGCTGCTGTAAGACAGTCTAAACTACGAAATACACCTTATCAGGCACCAGTTA
GAAGACAAATGAAAGCTAAGCAACTCAGTGCACAATCTTACGGTGTGACCAGTTCAACAGCTCGGCGAATATTGCAGTCTTTAGAGAAGA
TGTCAAGCCCTTTAGCGGATGCAAAAAGAATTCCATCCATTGTTTCTTCTCCTCTGAATTCTCCTCTTGATAGGAGTGGGATAGATATCA
CAGATTTTCAGGCCAAAAGAGAAAAGGTGGATTCTCAATATCCTCCTGTTCAGAGACTTATGACCCCAAAGCCAGTTTCCATAGCAACAA
ATCGAAGTGTTTATTTTAAACCATCTCTGACTCCTTCTGGTGAATTCAGGAAGACTAATCAAAGAATAGATAACAAGTGCAGTACTGGAT
ATGAAAAAAATATGACACCCGGACAAAATAGAGAACAACGAGAAAGTGGCTTTTCATATCCAAATTTCAGTTTGCCTGCAGCCAATGGTT
TATCTTCTGGAGTAGGTGGTGGAGGTGGCAAGATGAGACGAGAAAGAACACGCTTTGTTGCTTCTAAACCTCTGGAGGAGGAGAGACAAG
GTCTCACCGTATTGCCCAAGCTGATCTCGAGCTCCTGCGCTCAAGCGATCATCCCATCTTGGCCTCTCAAAGTGCTGAGATTACAGGAAA
TGGAAGTTCCAGTATTACCGAAAATCTCTCTACCGATCACCAGTTCTTCACTGCCTACCTTTAATTTTAGTTCCCCTGAGATCACAACTT
CCTCTCCATCACCCATCAATTCGTCTCAAGCATTAACAAACAAGGTACAAATGACCTCTCCGAGCAGCACTGGCAGTCCCATGTTTAAAT
TTTCATCTCCAATCGTAAAATCTACTGAGGCAAATGTACTACCTCCATCATCTATTGGATTTACATTTAGTGTGCCTGTTGCAAAAACAG
CAGAACTTTCTGGTTCTAGTAGTACTTTAGAACCAATTATAAGTAGTTCAGAGCCCATAGGCAGCATGTCATCCATGGAAGTGAACGTGG
ACATGCTGGAGCAGATGGACCTGATGGACATATCGGACCAGGAGGCCCTGGACGTCTTCCTGAACTCTGGAGGAGAAGAGAACACTGTGC
TGTCCCCCGCCTTAGGGCCTGAATCCAGTACCTGTCAGAATGAGATTACCCTCCAGGTTCCAAATCCCTCAGAATTAAGAGCCAAGCCAC
CTTCTTCTTCCTCCACCTGCACCGACTCGGCCACCCGGGACATCAGTGAGGGTGGGGAGTCCCCCGTTGTTCAGTCCGATGAGGAGGAAG
TTCAGGTGGACACTGCCCTGGCCACATCACACACTGACAGAGAGGCCACTCCGGATGGTGGTGAGGACAGCGACTCTTAAATTGGGACAT
GGGCGTTGTCTGGCCACACTGGAATCCAGTTTTGGCTGTATGCGGAATTCCACCTGGAAAGCCAGGTTGTTTTATAGAGGTTCTTGATTT

>60972_60972_6_NUP153-DTNBP1_NUP153_chr6_17646298_ENST00000537253_DTNBP1_chr6_15524900_ENST00000344537_length(amino acids)=733AA_BP=466
MASGAGGVGGGGGGKIRTRRCHQGPIKPYQQGRQQHQGILSRVTESVKNIVPGWLQRYFNKNEDVCSCSTDTSEVPRWPENKEDHLVYAD
EESSNITDGRITPEPAVSNTEEPSTTSTASNYPDVLTRPSLHRSHLNFSMLESPALHCQPSTSSAFPIGSSGFSLVKEIKDSTSQHDDDN
ISTTSGFSSRASDKDITVSKNTSLPPLWSPEAERSHSLSQHTATSSKKPAFNLSAFGTLSPSLGNSSILKTSQLGDSPFYPGKTTYGGAA
AAVRQSKLRNTPYQAPVRRQMKAKQLSAQSYGVTSSTARRILQSLEKMSSPLADAKRIPSIVSSPLNSPLDRSGIDITDFQAKREKVDSQ
YPPVQRLMTPKPVSIATNRSVYFKPSLTPSGEFRKTNQRIDNKCSTGYEKNMTPGQNREQRESGFSYPNFSLPAANGLSSGVGGGGGKMR
RERTRFVASKPLEEERQGLTVLPKLISSSCAQAIIPSWPLKVLRLQEMEVPVLPKISLPITSSSLPTFNFSSPEITTSSPSPINSSQALT
NKVQMTSPSSTGSPMFKFSSPIVKSTEANVLPPSSIGFTFSVPVAKTAELSGSSSTLEPIISSSEPIGSMSSMEVNVDMLEQMDLMDISD
QEALDVFLNSGGEENTVLSPALGPESSTCQNEITLQVPNPSELRAKPPSSSSTCTDSATRDISEGGESPVVQSDEEEVQVDTALATSHTD

--------------------------------------------------------------
>60972_60972_7_NUP153-DTNBP1_NUP153_chr6_17646298_ENST00000537253_DTNBP1_chr6_15524900_ENST00000355917_length(transcript)=2405nt_BP=1851nt
TTACCCGCCCCGGAGCGGGAAGCGGCGGAGGCTCCGCCATGGCCTCGGGAGCCGGAGGAGTCGGAGGGGGCGGTGGCGGCAAGATCCGGA
CGCGGCGTTGCCACCAGGGGCCAATTAAGCCTTACCAGCAGGGGCGACAACAGCATCAGGGCATTCTTAGCAGGGTTACAGAATCTGTTA
AGAATATTGTGCCAGGGTGGCTACAAAGATACTTCAACAAGAATGAAGATGTATGCAGCTGTTCAACAGACACAAGCGAGGTTCCACGCT
GGCCAGAAAATAAAGAGGACCATCTGGTATATGCCGATGAGGAGAGCTCTAATATTACTGATGGGAGAATCACACCTGAGCCAGCAGTCA
GTAATACAGAAGAACCTTCAACAACTAGTACTGCTTCAAATTATCCAGATGTGTTAACAAGGCCTTCTCTTCATCGGAGCCATCTGAATT
TTTCCATGTTGGAATCCCCTGCATTACACTGTCAGCCATCTACATCCTCGGCATTCCCAATTGGCAGTTCGGGATTTTCCCTTGTAAAGG
AAATTAAAGATTCTACCTCTCAGCATGATGATGATAACATCTCAACTACCAGTGGTTTTTCTTCAAGAGCTTCTGATAAAGATATAACTG
TTTCAAAGAACACTTCATTGCCACCTCTGTGGTCCCCAGAAGCTGAACGTTCTCACTCACTCTCACAGCACACTGCCACCAGCTCAAAAA
AACCAGCATTCAACTTGTCTGCCTTTGGAACACTTTCCCCTTCACTTGGGAATTCTTCAATCCTTAAAACCAGTCAGCTTGGAGATTCTC
CTTTTTATCCTGGAAAAACAACATACGGTGGGGCAGCAGCTGCTGTAAGACAGTCTAAACTACGAAATACACCTTATCAGGCACCAGTTA
GAAGACAAATGAAAGCTAAGCAACTCAGTGCACAATCTTACGGTGTGACCAGTTCAACAGCTCGGCGAATATTGCAGTCTTTAGAGAAGA
TGTCAAGCCCTTTAGCGGATGCAAAAAGAATTCCATCCATTGTTTCTTCTCCTCTGAATTCTCCTCTTGATAGGAGTGGGATAGATATCA
CAGATTTTCAGGCCAAAAGAGAAAAGGTGGATTCTCAATATCCTCCTGTTCAGAGACTTATGACCCCAAAGCCAGTTTCCATAGCAACAA
ATCGAAGTGTTTATTTTAAACCATCTCTGACTCCTTCTGGTGAATTCAGGAAGACTAATCAAAGAATAGATAACAAGTGCAGTACTGGAT
ATGAAAAAAATATGACACCCGGACAAAATAGAGAACAACGAGAAAGTGGCTTTTCATATCCAAATTTCAGTTTGCCTGCAGCCAATGGTT
TATCTTCTGGAGTAGGTGGTGGAGGTGGCAAGATGAGACGAGAAAGAACACGCTTTGTTGCTTCTAAACCTCTGGAGGAGGAGAGACAAG
GTCTCACCGTATTGCCCAAGCTGATCTCGAGCTCCTGCGCTCAAGCGATCATCCCATCTTGGCCTCTCAAAGTGCTGAGATTACAGGAAA
TGGAAGTTCCAGTATTACCGAAAATCTCTCTACCGATCACCAGTTCTTCACTGCCTACCTTTAATTTTAGTTCCCCTGAGATCACAACTT
CCTCTCCATCACCCATCAATTCGTCTCAAGCATTAACAAACAAGGTACAAATGACCTCTCCGAGCAGCACTGGCAGTCCCATGTTTAAAT
TTTCATCTCCAATCGTAAAATCTACTGAGGCAAATGTACTACCTCCATCATCTATTGGATTTACATTTAGTGTGCCTGTTGCAAAAACAG
CAGAACTTTCTGGTTCTAGTAGTACTTTAGAACCAATTATAAGTAGTTCAGAGCCCATAGGCAGCATGTCATCCATGGAAGTGAACGTGG
ACATGCTGGAGCAGATGGACCTGATGGACATATCGGACCAGGAGGCCCTGGACGTCTTCCTGAACTCTGGAGGAGAAGAGAACACTGTGC
TGTCCCCCGCCTTAGGGCCTGAATCCAGTACCTGTCAGAATGAGATTACCCTCCAGGTTCCAAATCCCTCAGAATTAAGAGCCAAGCCAC
CTTCTTCTTCCTCCACCTGCACCGACTCGGCCACCCGGGACATCAGTGAGGGTGGGGAGTCCCCCGTTGTTCAGTCCGATGAGGAGGAAG
TTCAGGTGGACACTGCCCTGGCCACATCACACACTGACAGAGAGGCCACTCCGGATGGTGGTGAGGACAGCGACTCTTAAATTGGGACAT
GGGCGTTGTCTGGCCACACTGGAATCCAGTTTTGGCTGTATGCGGAATTCCACCTGGAAAGCCAGGTTGTTTTATAGAGGTTCTTGATTT

>60972_60972_7_NUP153-DTNBP1_NUP153_chr6_17646298_ENST00000537253_DTNBP1_chr6_15524900_ENST00000355917_length(amino acids)=733AA_BP=466
MASGAGGVGGGGGGKIRTRRCHQGPIKPYQQGRQQHQGILSRVTESVKNIVPGWLQRYFNKNEDVCSCSTDTSEVPRWPENKEDHLVYAD
EESSNITDGRITPEPAVSNTEEPSTTSTASNYPDVLTRPSLHRSHLNFSMLESPALHCQPSTSSAFPIGSSGFSLVKEIKDSTSQHDDDN
ISTTSGFSSRASDKDITVSKNTSLPPLWSPEAERSHSLSQHTATSSKKPAFNLSAFGTLSPSLGNSSILKTSQLGDSPFYPGKTTYGGAA
AAVRQSKLRNTPYQAPVRRQMKAKQLSAQSYGVTSSTARRILQSLEKMSSPLADAKRIPSIVSSPLNSPLDRSGIDITDFQAKREKVDSQ
YPPVQRLMTPKPVSIATNRSVYFKPSLTPSGEFRKTNQRIDNKCSTGYEKNMTPGQNREQRESGFSYPNFSLPAANGLSSGVGGGGGKMR
RERTRFVASKPLEEERQGLTVLPKLISSSCAQAIIPSWPLKVLRLQEMEVPVLPKISLPITSSSLPTFNFSSPEITTSSPSPINSSQALT
NKVQMTSPSSTGSPMFKFSSPIVKSTEANVLPPSSIGFTFSVPVAKTAELSGSSSTLEPIISSSEPIGSMSSMEVNVDMLEQMDLMDISD
QEALDVFLNSGGEENTVLSPALGPESSTCQNEITLQVPNPSELRAKPPSSSSTCTDSATRDISEGGESPVVQSDEEEVQVDTALATSHTD

--------------------------------------------------------------
>60972_60972_8_NUP153-DTNBP1_NUP153_chr6_17646298_ENST00000537253_DTNBP1_chr6_15524900_ENST00000462989_length(transcript)=2408nt_BP=1851nt
TTACCCGCCCCGGAGCGGGAAGCGGCGGAGGCTCCGCCATGGCCTCGGGAGCCGGAGGAGTCGGAGGGGGCGGTGGCGGCAAGATCCGGA
CGCGGCGTTGCCACCAGGGGCCAATTAAGCCTTACCAGCAGGGGCGACAACAGCATCAGGGCATTCTTAGCAGGGTTACAGAATCTGTTA
AGAATATTGTGCCAGGGTGGCTACAAAGATACTTCAACAAGAATGAAGATGTATGCAGCTGTTCAACAGACACAAGCGAGGTTCCACGCT
GGCCAGAAAATAAAGAGGACCATCTGGTATATGCCGATGAGGAGAGCTCTAATATTACTGATGGGAGAATCACACCTGAGCCAGCAGTCA
GTAATACAGAAGAACCTTCAACAACTAGTACTGCTTCAAATTATCCAGATGTGTTAACAAGGCCTTCTCTTCATCGGAGCCATCTGAATT
TTTCCATGTTGGAATCCCCTGCATTACACTGTCAGCCATCTACATCCTCGGCATTCCCAATTGGCAGTTCGGGATTTTCCCTTGTAAAGG
AAATTAAAGATTCTACCTCTCAGCATGATGATGATAACATCTCAACTACCAGTGGTTTTTCTTCAAGAGCTTCTGATAAAGATATAACTG
TTTCAAAGAACACTTCATTGCCACCTCTGTGGTCCCCAGAAGCTGAACGTTCTCACTCACTCTCACAGCACACTGCCACCAGCTCAAAAA
AACCAGCATTCAACTTGTCTGCCTTTGGAACACTTTCCCCTTCACTTGGGAATTCTTCAATCCTTAAAACCAGTCAGCTTGGAGATTCTC
CTTTTTATCCTGGAAAAACAACATACGGTGGGGCAGCAGCTGCTGTAAGACAGTCTAAACTACGAAATACACCTTATCAGGCACCAGTTA
GAAGACAAATGAAAGCTAAGCAACTCAGTGCACAATCTTACGGTGTGACCAGTTCAACAGCTCGGCGAATATTGCAGTCTTTAGAGAAGA
TGTCAAGCCCTTTAGCGGATGCAAAAAGAATTCCATCCATTGTTTCTTCTCCTCTGAATTCTCCTCTTGATAGGAGTGGGATAGATATCA
CAGATTTTCAGGCCAAAAGAGAAAAGGTGGATTCTCAATATCCTCCTGTTCAGAGACTTATGACCCCAAAGCCAGTTTCCATAGCAACAA
ATCGAAGTGTTTATTTTAAACCATCTCTGACTCCTTCTGGTGAATTCAGGAAGACTAATCAAAGAATAGATAACAAGTGCAGTACTGGAT
ATGAAAAAAATATGACACCCGGACAAAATAGAGAACAACGAGAAAGTGGCTTTTCATATCCAAATTTCAGTTTGCCTGCAGCCAATGGTT
TATCTTCTGGAGTAGGTGGTGGAGGTGGCAAGATGAGACGAGAAAGAACACGCTTTGTTGCTTCTAAACCTCTGGAGGAGGAGAGACAAG
GTCTCACCGTATTGCCCAAGCTGATCTCGAGCTCCTGCGCTCAAGCGATCATCCCATCTTGGCCTCTCAAAGTGCTGAGATTACAGGAAA
TGGAAGTTCCAGTATTACCGAAAATCTCTCTACCGATCACCAGTTCTTCACTGCCTACCTTTAATTTTAGTTCCCCTGAGATCACAACTT
CCTCTCCATCACCCATCAATTCGTCTCAAGCATTAACAAACAAGGTACAAATGACCTCTCCGAGCAGCACTGGCAGTCCCATGTTTAAAT
TTTCATCTCCAATCGTAAAATCTACTGAGGCAAATGTACTACCTCCATCATCTATTGGATTTACATTTAGTGTGCCTGTTGCAAAAACAG
CAGAACTTTCTGGTTCTAGTAGTACTTTAGAACCAATTATAAGTAGTTCAGAGCCCATAGGCAGCATGTCATCCATGGAAGTGAACGTGG
ACATGCTGGAGCAGATGGACCTGATGGACATATCGGACCAGGAGGCCCTGGACGTCTTCCTGAACTCTGGAGGAGAAGAGAACACTGTGC
TGTCCCCCGCCTTAGGGCCTGAATCCAGTACCTGTCAGAATGAGATTACCCTCCAGGTTCCAAATCCCTCAGAATTAAGAGCCAAGCCAC
CTTCTTCTTCCTCCACCTGCACCGACTCGGCCACCCGGGACATCAGTGAGGGTGGGGAGTCCCCCGTTGTTCAGTCCGATGAGGAGGAAG
TTCAGGTGGACACTGCCCTGGCCACATCACACACTGACAGAGAGGCCACTCCGGATGGTGGTGAGGACAGCGACTCTTAAATTGGGACAT
GGGCGTTGTCTGGCCACACTGGAATCCAGTTTTGGCTGTATGCGGAATTCCACCTGGAAAGCCAGGTTGTTTTATAGAGGTTCTTGATTT

>60972_60972_8_NUP153-DTNBP1_NUP153_chr6_17646298_ENST00000537253_DTNBP1_chr6_15524900_ENST00000462989_length(amino acids)=733AA_BP=466
MASGAGGVGGGGGGKIRTRRCHQGPIKPYQQGRQQHQGILSRVTESVKNIVPGWLQRYFNKNEDVCSCSTDTSEVPRWPENKEDHLVYAD
EESSNITDGRITPEPAVSNTEEPSTTSTASNYPDVLTRPSLHRSHLNFSMLESPALHCQPSTSSAFPIGSSGFSLVKEIKDSTSQHDDDN
ISTTSGFSSRASDKDITVSKNTSLPPLWSPEAERSHSLSQHTATSSKKPAFNLSAFGTLSPSLGNSSILKTSQLGDSPFYPGKTTYGGAA
AAVRQSKLRNTPYQAPVRRQMKAKQLSAQSYGVTSSTARRILQSLEKMSSPLADAKRIPSIVSSPLNSPLDRSGIDITDFQAKREKVDSQ
YPPVQRLMTPKPVSIATNRSVYFKPSLTPSGEFRKTNQRIDNKCSTGYEKNMTPGQNREQRESGFSYPNFSLPAANGLSSGVGGGGGKMR
RERTRFVASKPLEEERQGLTVLPKLISSSCAQAIIPSWPLKVLRLQEMEVPVLPKISLPITSSSLPTFNFSSPEITTSSPSPINSSQALT
NKVQMTSPSSTGSPMFKFSSPIVKSTEANVLPPSSIGFTFSVPVAKTAELSGSSSTLEPIISSSEPIGSMSSMEVNVDMLEQMDLMDISD
QEALDVFLNSGGEENTVLSPALGPESSTCQNEITLQVPNPSELRAKPPSSSSTCTDSATRDISEGGESPVVQSDEEEVQVDTALATSHTD

--------------------------------------------------------------

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Fusion Gene PPI Analysis for NUP153-DTNBP1


check button Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in

ChiPPI page.


check button Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160)
HgeneHgene's interactorsTgeneTgene's interactors


check button - Retained PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenStill interaction with


check button - Lost PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


check button - Retained PPIs, but lost function due to frame-shift fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


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Related Drugs for NUP153-DTNBP1


check button Drugs targeting genes involved in this fusion gene.
(DrugBank Version 5.1.8 2021-05-08)
PartnerGeneUniProtAccDrugBank IDDrug nameDrug activityDrug typeDrug status

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Related Diseases for NUP153-DTNBP1


check button Diseases associated with fusion partners.
(DisGeNet 4.0)
PartnerGeneDisease IDDisease name# pubmedsSource