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Center for Computational Systems Medicine
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Fusion Gene Summary

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Fusion Gene ORF analysis

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Fusion Genomic Features

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Fusion Protein Features

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Fusion Gene Sequence

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Fusion Gene PPI analysis

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Related Drugs

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Related Diseases

Fusion gene:NUP155-ANKH (FusionGDB2 ID:60984)

Fusion Gene Summary for NUP155-ANKH

check button Fusion gene summary
Fusion gene informationFusion gene name: NUP155-ANKH
Fusion gene ID: 60984
HgeneTgene
Gene symbol

NUP155

ANKH

Gene ID

9631

56172

Gene namenucleoporin 155ANKH inorganic pyrophosphate transport regulator
SynonymsATFB15|N155ANK|CCAL2|CMDJ|CPPDD|HANK|MANK|SLC62A1
Cytomap

5p13.2

5p15.2

Type of geneprotein-codingprotein-coding
Descriptionnuclear pore complex protein Nup155155 kDa nucleoporinnucleoporin 155kDnucleoporin 155kDaprogressive ankylosis protein homologankylosis, progressive homolog
Modification date2020032920200313
UniProtAcc.

Q8IWZ3

Ensembl transtripts involved in fusion geneENST00000231498, ENST00000513532, 
ENST00000381843, ENST00000502533, 
ENST00000503939, ENST00000284268, 
ENST00000535119, 
Fusion gene scores* DoF score8 X 8 X 6=38413 X 11 X 7=1001
# samples 814
** MAII scorelog2(8/384*10)=-2.26303440583379
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0		log2(14/1001*10)=-2.83794324189103
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0
Context

PubMed: NUP155 [Title/Abstract] AND ANKH [Title/Abstract] AND fusion [Title/Abstract]

Most frequent breakpointNUP155(37370923)-ANKH(14742031), # samples:2
Anticipated loss of major functional domain due to fusion event.
* DoF score (Degree of Frequency) = # partners X # break points X # cancer types
** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)

check button Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez
PartnerGeneGO IDGO termPubMed ID
HgeneNUP155

GO:0006998

nuclear envelope organization

19070573


check buttonFusion gene breakpoints across NUP155 (5'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check buttonFusion gene breakpoints across ANKH (3'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check button Fusion gene information from two resources (ChiTars 5.0 and ChimerDB 4.0)
* All genome coordinats were lifted-over on hg19.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
SourceDiseaseSampleHgeneHchrHbpHstrandTgeneTchrTbpTstrand
ChimerDB4SKCMTCGA-BF-A5ES-01ANUP155chr5

37370768

-ANKHchr5

14742031

-
ChimerDB4SKCMTCGA-BF-A5ES-01ANUP155chr5

37370923

-ANKHchr5

14742031

-


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Fusion Gene ORF analysis for NUP155-ANKH

check button Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
ORFHenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrand
5CDS-5UTRENST00000231498ENST00000503939NUP155chr5

37370923

-ANKHchr5

14742031

-
5CDS-5UTRENST00000513532ENST00000503939NUP155chr5

37370923

-ANKHchr5

14742031

-
5UTR-3CDSENST00000381843ENST00000284268NUP155chr5

37370768

-ANKHchr5

14742031

-
5UTR-3CDSENST00000381843ENST00000535119NUP155chr5

37370768

-ANKHchr5

14742031

-
5UTR-5UTRENST00000381843ENST00000503939NUP155chr5

37370768

-ANKHchr5

14742031

-
In-frameENST00000231498ENST00000284268NUP155chr5

37370923

-ANKHchr5

14742031

-
In-frameENST00000231498ENST00000535119NUP155chr5

37370923

-ANKHchr5

14742031

-
In-frameENST00000513532ENST00000284268NUP155chr5

37370923

-ANKHchr5

14742031

-
In-frameENST00000513532ENST00000535119NUP155chr5

37370923

-ANKHchr5

14742031

-
intron-3CDSENST00000231498ENST00000284268NUP155chr5

37370768

-ANKHchr5

14742031

-
intron-3CDSENST00000231498ENST00000535119NUP155chr5

37370768

-ANKHchr5

14742031

-
intron-3CDSENST00000381843ENST00000284268NUP155chr5

37370923

-ANKHchr5

14742031

-
intron-3CDSENST00000381843ENST00000535119NUP155chr5

37370923

-ANKHchr5

14742031

-
intron-3CDSENST00000502533ENST00000284268NUP155chr5

37370768

-ANKHchr5

14742031

-
intron-3CDSENST00000502533ENST00000284268NUP155chr5

37370923

-ANKHchr5

14742031

-
intron-3CDSENST00000502533ENST00000535119NUP155chr5

37370768

-ANKHchr5

14742031

-
intron-3CDSENST00000502533ENST00000535119NUP155chr5

37370923

-ANKHchr5

14742031

-
intron-3CDSENST00000513532ENST00000284268NUP155chr5

37370768

-ANKHchr5

14742031

-
intron-3CDSENST00000513532ENST00000535119NUP155chr5

37370768

-ANKHchr5

14742031

-
intron-5UTRENST00000231498ENST00000503939NUP155chr5

37370768

-ANKHchr5

14742031

-
intron-5UTRENST00000381843ENST00000503939NUP155chr5

37370923

-ANKHchr5

14742031

-
intron-5UTRENST00000502533ENST00000503939NUP155chr5

37370768

-ANKHchr5

14742031

-
intron-5UTRENST00000502533ENST00000503939NUP155chr5

37370923

-ANKHchr5

14742031

-
intron-5UTRENST00000513532ENST00000503939NUP155chr5

37370768

-ANKHchr5

14742031

-

check buttonORFfinder result based on the fusion transcript sequence of in-frame fusion genes.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandSeq length
(transcript)		BP loci
(transcript)		Predicted start
(transcript)		Predicted stop
(transcript)		Seq length
(amino acids)
ENST00000231498NUP155chr537370923-ENST00000284268ANKHchr514742031-7318361166924252
ENST00000231498NUP155chr537370923-ENST00000535119ANKHchr514742031-1712361166924252
ENST00000513532NUP155chr537370923-ENST00000284268ANKHchr514742031-721826166824252
ENST00000513532NUP155chr537370923-ENST00000535119ANKHchr514742031-161226166824252

check buttonDeepORF prediction of the coding potential based on the fusion transcript sequence of in-frame fusion genes. DeepORF is a coding potential classifier based on convolutional neural network by comparing the real Ribo-seq data. If the no-coding score < 0.5 and coding score > 0.5, then the in-frame fusion transcript is predicted as being likely translated.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandNo-coding scoreCoding score
ENST00000231498ENST00000284268NUP155chr537370923-ANKHchr514742031-0.0051744030.9948256
ENST00000231498ENST00000535119NUP155chr537370923-ANKHchr514742031-0.0061840040.993816
ENST00000513532ENST00000284268NUP155chr537370923-ANKHchr514742031-0.0051012970.99489874
ENST00000513532ENST00000535119NUP155chr537370923-ANKHchr514742031-0.0051957820.9948042

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Fusion Genomic Features for NUP155-ANKH


check buttonFusionAI prediction of the potential fusion gene breakpoint based on the pre-mature RNA sequence context (+/- 5kb of individual partner genes, total 20kb length sequence). FusionAI is a fusion gene breakpoint classifier based on convolutional neural network by comparing the fusion positive and negative sequence context of ~ 20K fusion gene data. From here, we can have the relative potentency of the 20K genomic sequence how individual sequnce will be likely used as the gene fusion breakpoints.
HgeneHchrHbpHstrandTgeneTchrTbpTstrand1-pp (fusion gene breakpoint)

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions. We integrated a total of 44 different types of human genomic feature loci information across five big categories including virus integration sites, repeats, structural variants, chromatin states, and gene expression regulation. More details are in help page.
genomic feature

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions that are ovelapped with the top 1% feature importance score regions. More details are in help page.

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Fusion Protein Features for NUP155-ANKH


check button Four levels of functional features of fusion genes
Go to FGviewer search page for the most frequent breakpoint (https://ccsmweb.uth.edu/FGviewer/chr5:37370923/chr5:14742031)
- FGviewer provides the online visualization of the retention search of the protein functional features across DNA, RNA, protein, and pathological levels.
- How to search
1. Put your fusion gene symbol.
2. Press the tab key until there will be shown the breakpoint information filled.
4. Go down and press 'Search' tab twice.
4. Go down to have the hyperlink of the search result.
5. Click the hyperlink.
6. See the FGviewer result for your fusion gene.
FGviewer

check buttonMain function of each fusion partner protein. (from UniProt)
HgeneTgene
.ANKH

Q8IWZ3

FUNCTION: Transcriptional activator which is required for calcium-dependent dendritic growth and branching in cortical neurons. Recruits CREB-binding protein (CREBBP) to nuclear bodies. Component of the CREST-BRG1 complex, a multiprotein complex that regulates promoter activation by orchestrating a calcium-dependent release of a repressor complex and a recruitment of an activator complex. In resting neurons, transcription of the c-FOS promoter is inhibited by BRG1-dependent recruitment of a phospho-RB1-HDAC1 repressor complex. Upon calcium influx, RB1 is dephosphorylated by calcineurin, which leads to release of the repressor complex. At the same time, there is increased recruitment of CREBBP to the promoter by a CREST-dependent mechanism, which leads to transcriptional activation. The CREST-BRG1 complex also binds to the NR2B promoter, and activity-dependent induction of NR2B expression involves a release of HDAC1 and recruitment of CREBBP (By similarity). {ECO:0000250}.FUNCTION: May play a role as a scaffolding protein that may be associated with the abnormal phenotype of leukemia cells. Isoform 2 may possess an antiapoptotic effect and protect cells during normal cell survival through its regulation of caspases. {ECO:0000269|PubMed:16098192}.

check buttonRetention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at

download page


* Minus value of BPloci means that the break pointn is located before the CDS.
- In-frame and retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
TgeneANKHchr5:37370923chr5:14742031ENST00000284268612348_350305493.0Topological domainExtracellular
TgeneANKHchr5:37370923chr5:14742031ENST00000284268612372_403305493.0Topological domainCytoplasmic
TgeneANKHchr5:37370923chr5:14742031ENST00000284268612427_429305493.0Topological domainExtracellular
TgeneANKHchr5:37370923chr5:14742031ENST00000284268612453_492305493.0Topological domainCytoplasmic
TgeneANKHchr5:37370923chr5:14742031ENST00000284268612327_347305493.0TransmembraneHelical
TgeneANKHchr5:37370923chr5:14742031ENST00000284268612351_371305493.0TransmembraneHelical
TgeneANKHchr5:37370923chr5:14742031ENST00000284268612404_426305493.0TransmembraneHelical
TgeneANKHchr5:37370923chr5:14742031ENST00000284268612430_452305493.0TransmembraneHelical

- In-frame and not-retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneNUP155chr5:37370923chr5:14742031ENST00000231498-135585_655521392.0Compositional biasNote=Pro-rich
HgeneNUP155chr5:37370923chr5:14742031ENST00000381843-135585_65501333.0Compositional biasNote=Pro-rich
TgeneANKHchr5:37370923chr5:14742031ENST00000284268612107_131305493.0Topological domainExtracellular
TgeneANKHchr5:37370923chr5:14742031ENST00000284268612153_158305493.0Topological domainCytoplasmic
TgeneANKHchr5:37370923chr5:14742031ENST00000284268612180_189305493.0Topological domainExtracellular
TgeneANKHchr5:37370923chr5:14742031ENST000002842686121_85305493.0Topological domainCytoplasmic
TgeneANKHchr5:37370923chr5:14742031ENST00000284268612211_326305493.0Topological domainCytoplasmic
TgeneANKHchr5:37370923chr5:14742031ENST00000284268612132_152305493.0TransmembraneHelical
TgeneANKHchr5:37370923chr5:14742031ENST00000284268612159_179305493.0TransmembraneHelical
TgeneANKHchr5:37370923chr5:14742031ENST00000284268612190_210305493.0TransmembraneHelical
TgeneANKHchr5:37370923chr5:14742031ENST0000028426861286_106305493.0TransmembraneHelical


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Fusion Gene Sequence for NUP155-ANKH


check button For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. To have fusion amino acid sequence, we ran ORFfinder and chose the longest ORF among the all predicted ones.
>60984_60984_1_NUP155-ANKH_NUP155_chr5_37370923_ENST00000231498_ANKH_chr5_14742031_ENST00000284268_length(transcript)=7318nt_BP=361nt
CTCCCAACAGCTTCCTCTTCCCAGGCCAGAACGGCGTCTTCCAGTTCCCCACCGGATGAAGCGGAAGTGCGTCATGTCGAGGCGCCAAGG
CGCTCGTTTGGCGCGCGCGCCCTAGGCGGCGGATCTAAGCTAACTTCTTGGATCTTTTCTTGTTTCTCCTTGGTTTTTGACTTTTTCTGG
ACCCTGGTGTCTACGATTTCCGAGATGCCGTCTTCTTTGTTGGGCGCGGCGATGCCGGCCTCTACATCTGCCGCAGCCCTGCAGGAAGCT
CTGGAAAATGCTGGACGGCTCATCGACCGTCAGTTGCAAGAGGACCGCATGTACCCGGACCTTTCCGAGCTGCTTATGGTGTCTGCCCCA
AAATAACCCCAGCAACAAACTGGTGAGCACGAGCAACACAGTCACGGCAGCCCACATCAAGAAGTTCACCTTCGTCTGCATGGCTCTGTC
ACTCACGCTCTGTTTCGTGATGTTTTGGACACCCAACGTGTCTGAGAAAATCTTGATAGACATCATCGGAGTGGACTTTGCCTTTGCAGA
ACTCTGTGTTGTTCCTTTGCGGATCTTCTCCTTCTTCCCAGTTCCAGTCACAGTGAGGGCGCATCTCACCGGGTGGCTGATGACACTGAA
GAAAACCTTCGTCCTTGCCCCCAGCTCTGTGCTGCGGATCATCGTCCTCATCGCCAGCCTCGTGGTCCTACCCTACCTGGGGGTGCACGG
TGCGACCCTGGGCGTGGGCTCCCTCCTGGCGGGCTTTGTGGGAGAATCCACCATGGTCGCCATCGCTGCGTGCTATGTCTACCGGAAGCA
GAAAAAGAAGATGGAGAATGAGTCGGCCACGGAGGGGGAAGACTCTGCCATGACAGACATGCCTCCGACAGAGGAGGTGACAGACATCGT
GGAAATGAGAGAGGAGAATGAATAAGGCACGGGACGCCATGGGCACTGCAGGGACAGTCAGTCAGGATGACACTTCGGCATCATCTCTTC
CCTCTCCCATCGTATTTTGTTCCCTTTTTTTTGTTTTGTTTTGGTAATGAAAGAGGCCTTGATTTAAAGGTTTCGTGTCAATTCTCTAGC
ATACTGGGTATGCTCACACTGACGGGGGGACCTAGTGAATGGTCTTTACTGTTGCTATGTAAAAACAAACGAAACAACTGACTTCATACC
CCTGCCTCACGAAAACCCAAAAGACACAGCTGCCTCACGGTTGACGTTGTGTCCTCCTCCCCTGGACAATCTCCTCTTGGAACCAAAGGA
CTGCAGCTGTGCCATCGCGCCTCGGTCACCCTGCACAGCAGGCCACAGACTCTCCTGTCCCCCTTCATCGCTCTTAAGAATCAACAGGTT
AAAACTCGGCTTCCTTTGATTTGCTTCCCAGTCACATGGCCGTACAAAGAGATGGAGCCCCGGTGGCCTCTTAAATTTCCCTTCCGCCAC
GGAGTTCGAAACCATCTACTCCACACATGCAGGAGGCGGGTGGCACGCTGCAGCCCGGAGTCCCCGTTCACACTGAGGAACGGAGACCTG
TGACCACAGCAGGCTGACAGATGGACAGAATCTCCCGTAGAAAGGTTTGGTTTGAAATGCCCCGGGGGCAGCAAACTGACATGGTTGAAT
GATAGCATTTCACTCTGCGTTCTCCTAGATCTGAGCAAGCTGTCAGTTCTCACCCCCACCGTGTATATACATGAGCTAACTTTTTTAAAT
TGTCACAAAAGCGCATCTCCAGATTCCAGACCCTGCCGCATGACTTTTCCTGAAGGCTTGCTTTTCCCTCGCCTTTCCTGAAGGTCGCAT
TAGAGCGAGTCACATGGAGCATCCTAACTTTGCATTTTAGTTTTTACAGTGAACTGAAGCTTTAAGTCTCATCCAGCATTCTAATGCCAG
GTTGCTGTAGGGTAACTTTTGAAGTAGATATATTACCTGGTTCTGCTATCCTTAGTCATAACTCTGCGGTACAGGTAATTGAGAATGTAC
TACGGTACTTCCCTCCCACACCATACGATAAAGCAAGACATTTTATAACGATACCAGAGTCACTATGTGGTCCTCCCTGAAATAACGCAT
TCGAAATCCATGCAGTGCAGTATATTTTTCTAAGTTTTGGAAAGCAGGTTTTTTCCTTTAAAAAAATTATAGACACGGTTCACTAAATTG
ATTTAGTCAGAATTCCTAGACTGAAAGAACCTAAAAAAAAAAATATTTTAAAGATATAAATATATGCTGTATATGTTATGTAATTTATTT
TAGGCTATAATACATTTCCTATTTTCGCATTTTCAATAAAATGTCTCTAATACAATACGGTGATTGCTTGTGTGCTCAACATACCTGCAG
TTGAAACGTATTGTATCAATGAACATTGTACCTTATTGGCAGCAGTTTTATAAAGTCCGTCATTTGCATTTGAATGTAAGGCTCAGTAAA
TGACAGAACTATTTTTCATTATGGGTAACTGGGGAATAAATGGGTCACTGGAGTAGGAATAGAAGTGCAAGCTGGAAAGGCAAAAATGAG
AAAGAAAAAGGCAGGCCCTTTGTGTCTACCGTTTTCAGTGCTGTGTGATCATATTGTTCCTCACAGCAAAAAAGAATGCAAGGGCATAAT
GTTAGCTGTGAACATGCCAGGGTTGCATTCACATTCCTGGGTACCCAGTGCTGATGGGGTGTGCCCACGTGGGGACATGTCCTTGGCGTG
CTTCCTCAGAGTGGCTTTTCCTCCATTAATACATATATGAGTACTGAAAAATTAAGTTGCATAGCTGCTTTGCAGTGGTTTCAGAGGCAG
ATCTGAGAAGATTAAAAAAAAATCTCAATGTATCAGCTTTTTTTAAAGGACATTACTAGAAAATTAAACAGTATTTTTTAACATGTGTGA
CTTTCATGCTTCTGGGGTTGGAGCTTAAAGATCCAAACTGAGAAAGCAGGCCGGGCATGGTGGCTCATGCCTGTAATCCCAACACTTTGG
GAGGCCAAGGAGGGTGGATCACTTAAGGTCAGGAGTTTGAGACCAGCCTGGCCAACATGGCAAAACCCTGTCTCTACTAAAAACATAAAA
ATTAGCTGGGGGTGGTAGCACATACCTGTAATCCCAGCTACTCAGGAGGCTGAGGCAGGAGAATTTGCTTGATCCTGGGAGGCAGAGGTT
GTAGTGAGCCGAGATCGCGCCATCGCACTCCAGCCTGGGTGACAAGAGCAAAACTCCATCTCAAAAAAAAAAAAAATCCTTTCCCTCTAA
ATCCAGGAAGGATCAGCAAGGGCCTCCTCATTATGAGATGAGGAAATACAACTCCAGAGATTCCTTCAGTGATCAAGATCAGTGGGCCAT
AATATTTGGTTAGAGTTTCTGAGAACACAGGAAGCAATGCCACACTCAGGCCACCACAATGGAGCTGATTTGGCAGGACTTGTTCAAACC
TTTCACCTTAAAGCACGTGATCCTTCTTCGTACATTTTCTTCACTTGGGCTGCTTAAGTCACAGCCTAACAACTTTGAGGCAAAACTGAG
AACTGGCATATTCTCCTGCGTTTCTTCTAATCGAGTCCCATCATCCAGCTAGACATGAGAGATCAAACCAGGGAGGGTGACCTTTCTCCT
TCCCACTTTTCAGAGTCATTGGGGCAACTTTTTGACTTTTGTGACCAAAGAAACATTCCCCCAAAACATTTATTTTTCATTGTAGGGCAT
TCAGCTGACAGCTGCATTTTAGAAAGTTACCATGCCTGTGAGATTCTCATGTCAAAGACCAGGGAAAGACCAGGTGTGACTTTCTCCAAA
ACTGAGTGATTGCTTGTGGATGAATACAATCTAAAAATACAAGGCCATGAAGTAGTTTTTCATTTAGATGCTGAGAAATAATAGGTTTGG
GCAGCTCAAAGCATAGGAAATAGTAAGGGTTTTCTAGAGCTCCTCCTTTGGTGGCCTGTTTGAGTAGCACAAGGGACGTCATCCTAAATG
TGCAGTTGCCATTTGTTCTGTAGTGACTTACAGGGATCTCAGTGGCAAAGGGCGTCAGTGAGACAACAACTGAGCAAAAAGAACTAGACG
AGGCTTGCGCTTGGAAAGTCACGGTAGGATTGGACCTGCCGGCCACATGGCTCAGGGAGTATTGACGGATTTGCACATTGGCAGGAAACT
CTCCCGTTTGGGATTCTTTAAATGGGGCACAGAAGGCCACTTGTTTGCATTTCTGGGTAAAAAACAGTCATCCCCCATGACTGCCTGCAT
CGGGTTTGTCTTGTGCCAAAGTTACTCTTCCTTTGTTTTTACTTTGCCTTGATTTTTAGCATTAGCTGGTAGTTTGGCTTGGAAATGTCC
TGGATAGCCGATTCCCTAAGAAACTGAAACATTTAATATTGGCTTAGGATGTATCAGATGGGGCCAAATAAAGCTTCTTTACAATAGTAA
AAGCACTTTATACTTCACTCTCTGAGTCTTCCCAATAAATAACCTTGGGAGGTGCAGGGGGTGGGGGGCCCAGGATGGGGAGGCCTGGGA
GCTCCCAGGGTAGTGACAGAGTTGGGCTGAGTTCTCCAGACGCCAGGATGCGTCGCAGCGGGGCCAGCTCAGGAGTGCTCACTCCCAGCC
CTCTGGATCTCTCTCCTGGTTGGAATAATCATTACATATCGTAACTCTCAAAATTTATTCACTTATATTTTCAGAATAAGAAGTGTGAAA
TGTTAACAGCTCTCTGCTCTCTTACTTGTTCCCCATTTGGGGATCTTCTGGAGGGAAGGGGCAGGGGGAGAGTAACTTTTCTATATCCTT
GGTTTCTAGGAACACATCGATTTGAAGACTCAGTAGCTGACTGGTTTTTTTTTTTCCCCCTTCAAACTGAAGTGCGAGTGTGCGTGTGTT
CCACAAAATAGCAAGTATTTATAGTGTTGTAATTACATTTCCTTGAGAAATATTTTCTTGTATTTAAAAATCTTTCTACTTCAGTAACTC
CCAGCAGAACAGTGCCCAGGACAGCATGTGCCGGTTAGTACCAGCTTTGCAGGTGAGCTGACTTCTAAACTTAGGACGACGTCTTCATCA
ATCAAACTAGTGCACAGTCCAGAAAAAGGGGTCCTTTATCTTCTAAGTTCTGCTCCTCACCTTTCTTTGGAACCAAAATTGCAGTGGAGT
GTGAGGAAGAGCTTTGAAAGACGTGGAGTGTTGAGATGTCTGCATTGCACATTCAGCCGGTTCAAAGCCAGCAGCTCCTGCCTGCATTCT
GTAGACATCGCCCTCACACACAGTCCTCTGATGGCTCTCATATAAAGCACTCAAACCGTAGGAAAGCATGTTTTTGAGCAACGTGTCTGG
GATACTCCTCTGTGTGGTTATTTTGAATCTCTATTTCTGTCATTGAAGCAGCAAAAAACATCATGTGACTCATCAACTGATCTAATCACA
CTTAAAACAGGATGTAGAGAAAAATCTGATGAGAAACGTAAAAGGGCCTGTTGCCTGCCCTTTTAAAGGCAAAATGTCTAAAATCATGCA
AATGTTCAAAATGAGAGAAATTGCATTGTGGAATCAAAATAACCCAAACTCCACTCAGAAAAGTCACAAATATATAGTATACTATCTGAT
CTCAAAAGGGAAAAACGAGATGATAAGACCTTAAGTTTAGACTTTATTTTCTTCTCAAGAGTGGACATTAAATCTATTAACTTGCAACTT
TCTGCTGGGAAGAGCATCAAAGGTGGGCCTCCTAAATCATTTTTGAAAAACCTCTGTCAAGTCCAAGTGGTTCCAGGAGAATTATAGCCA
GTATCTTTTAAAATATTTCATTTTAGTGATAATGTTTTTCTCTGCTTCATTTGCAATCAACCAGGATCTCTAAAAGACTGCATAAGATAT
ATGCACTTTTATAGGTGGCTGTCAGCTACACATAGATTCAGCAAATTTTTTTTATATAGTACCTGTTTTTAAGTTAGGCTACATAACTTA
AAGTGCACTTTACTAACAAGACTTGACATTAGCGTCTACAATATGTATATGTAAACAAAAGCACACAAGAACTAGGCACCCTTTCTCTCT
CCAAGAGTTTAAGTGGTTTCCTTAGGTTAAAGAAGGGGACAGACCAGCTAAAAATGGTTGTACCACTCACTGTACAACCTCATGGAAATT
CTCACTATAAGATTTAGAGGCAATGTTCCCTAGCTATAAGCCAGGGCAAGAAATGGCGCCTCTGGAGTTGGGGAACATTAGGGGAACATT
ACAACCGGGTAGATGCTGGTTCCCTGAAGTGTGGGGCCATGAACATGCAGGGACCCACGGTTTGAATGAAACAGCTACTGAAAGCTAAGT
TCAAACCACCCTTGCGTAACAAAGGAGTACAGGGTACACATCAACACCAATCACCCAGCACCCCACAGCGATGGTCATGTCACCGTGCAG
CAGGTCCCTTACCCCAGGGCTGCCACATCCACAAGCCTTGCAGTGGCAAATACGCTGCTCCTTGGATTTAATGAGATATTTTGGTTGCTT
AATGATGTACTGATCAGGGAACTGTCTAAAGCTAGTAGGGCCAAGGAGTTAATCAAAGGGCTTCGGGAAAGTGGACAAGAGCCACACACG
TGATTCTGTTCCATGCCGACACTCATTCATTTAAGAAGTGTATTCAAGCTGGAGGCTTCCATATCACTCACGCTTCTTGGCCTCACCTTG
CTCATCTGTCCAATGGGAGGCTTGAGCCATTATTGCTAAGGCCCCTTCCTGATCTAACATTCTGTTTATGATCTAGGATTTAGAACGTCG
TATGAGATCCTACAATGGAAGAATAAAATCACCTCATTCTTCATTTCAGATCTGAACATTAGCAGTGATCTAGATTTTTTTTTTTTTAAA
CAAAATTAAGTGTGCTTAGAGTCATTCCTCTACATGGGCTGTGGCTGTCAGCCCATAGGTTTGTCAGTTTCACATCAAAACTGTGGGTAT
AAACTGTTGAAACCAATCACATTAAAATATTTAGCTGGGCACAGTGGTGTGCATCTGTAGTCCCAGCTACTTGGGAGGCTGAGGCAGGAG
GATCGCTTAAGCACAGGAGTTGGAATCCAGCCTGAGCAACAGAGCAAAACCCCGTCTCTAAAATACAAATAAAATATTTGTGTAGTTTTT
GATTAAAATTGACTACAGCGGTCAGTATAAAATACATGTCGCTTTTAAGGAAGTGCTCTTTATGTATCTAACAGATGGAAGTTTTTGCAT
TGGTAAGAGCATTTATATATGCTTTGTTTCAGGGTTTATGGATTTGTATTCATATATTGTCAAATAGGTTTCATACTCTAATTTTACTTT

>60984_60984_1_NUP155-ANKH_NUP155_chr5_37370923_ENST00000231498_ANKH_chr5_14742031_ENST00000284268_length(amino acids)=252AA_BP=63
MTFSGPWCLRFPRCRLLCWARRCRPLHLPQPCRKLWKMLDGSSTVSCKRTACTRTFPSCLWCLPQNNPSNKLVSTSNTVTAAHIKKFTFV
CMALSLTLCFVMFWTPNVSEKILIDIIGVDFAFAELCVVPLRIFSFFPVPVTVRAHLTGWLMTLKKTFVLAPSSVLRIIVLIASLVVLPY

--------------------------------------------------------------
>60984_60984_2_NUP155-ANKH_NUP155_chr5_37370923_ENST00000231498_ANKH_chr5_14742031_ENST00000535119_length(transcript)=1712nt_BP=361nt
CTCCCAACAGCTTCCTCTTCCCAGGCCAGAACGGCGTCTTCCAGTTCCCCACCGGATGAAGCGGAAGTGCGTCATGTCGAGGCGCCAAGG
CGCTCGTTTGGCGCGCGCGCCCTAGGCGGCGGATCTAAGCTAACTTCTTGGATCTTTTCTTGTTTCTCCTTGGTTTTTGACTTTTTCTGG
ACCCTGGTGTCTACGATTTCCGAGATGCCGTCTTCTTTGTTGGGCGCGGCGATGCCGGCCTCTACATCTGCCGCAGCCCTGCAGGAAGCT
CTGGAAAATGCTGGACGGCTCATCGACCGTCAGTTGCAAGAGGACCGCATGTACCCGGACCTTTCCGAGCTGCTTATGGTGTCTGCCCCA
AAATAACCCCAGCAACAAACTGGTGAGCACGAGCAACACAGTCACGGCAGCCCACATCAAGAAGTTCACCTTCGTCTGCATGGCTCTGTC
ACTCACGCTCTGTTTCGTGATGTTTTGGACACCCAACGTGTCTGAGAAAATCTTGATAGACATCATCGGAGTGGACTTTGCCTTTGCAGA
ACTCTGTGTTGTTCCTTTGCGGATCTTCTCCTTCTTCCCAGTTCCAGTCACAGTGAGGGCGCATCTCACCGGGTGGCTGATGACACTGAA
GAAAACCTTCGTCCTTGCCCCCAGCTCTGTGCTGCGGATCATCGTCCTCATCGCCAGCCTCGTGGTCCTACCCTACCTGGGGGTGCACGG
TGCGACCCTGGGCGTGGGCTCCCTCCTGGCGGGCTTTGTGGGAGAATCCACCATGGTCGCCATCGCTGCGTGCTATGTCTACCGGAAGCA
GAAAAAGAAGATGGAGAATGAGTCGGCCACGGAGGGGGAAGACTCTGCCATGACAGACATGCCTCCGACAGAGGAGGTGACAGACATCGT
GGAAATGAGAGAGGAGAATGAATAAGGCACGGGACGCCATGGGCACTGCAGGGACAGTCAGTCAGGATGACACTTCGGCATCATCTCTTC
CCTCTCCCATCGTATTTTGTTCCCTTTTTTTTGTTTTGTTTTGGTAATGAAAGAGGCCTTGATTTAAAGGTTTCGTGTCAATTCTCTAGC
ATACTGGGTATGCCCCTTCCTGATCTAACATTCTGTTTATGATCTAGGATTTAGAACGTCGTATGAGATCCTACAATGGAAGAATAAAAT
CACCTCATTCTTCATTTCAGATCTGAACATTAGCAGTGATCTAGATTTTTTTTTTTTTAAACAAAATTAAGTGTGCTTAGAGTCATTCCT
CTACATGGGCTGTGGCTGTCAGCCCATAGGTTTGTCAGTTTCACATCAAAACTGTGGGTATAAACTGTTGAAACCAATCACATTAAAATA
TTTAGCTGGGCACAGTGGTGTGCATCTGTAGTCCCAGCTACTTGGGAGGCTGAGGCAGGAGGATCGCTTAAGCACAGGAGTTGGAATCCA
GCCTGAGCAACAGAGCAAAACCCCGTCTCTAAAATACAAATAAAATATTTGTGTAGTTTTTGATTAAAATTGACTACAGCGGTCAGTATA
AAATACATGTCGCTTTTAAGGAAGTGCTCTTTATGTATCTAACAGATGGAAGTTTTTGCATTGGTAAGAGCATTTATATATGCTTTGTTT
CAGGGTTTATGGATTTGTATTCATATATTGTCAAATAGGTTTCATACTCTAATTTTACTTTAAGTAAAGCTTAAACACTTGGCATACAAC

>60984_60984_2_NUP155-ANKH_NUP155_chr5_37370923_ENST00000231498_ANKH_chr5_14742031_ENST00000535119_length(amino acids)=252AA_BP=63
MTFSGPWCLRFPRCRLLCWARRCRPLHLPQPCRKLWKMLDGSSTVSCKRTACTRTFPSCLWCLPQNNPSNKLVSTSNTVTAAHIKKFTFV
CMALSLTLCFVMFWTPNVSEKILIDIIGVDFAFAELCVVPLRIFSFFPVPVTVRAHLTGWLMTLKKTFVLAPSSVLRIIVLIASLVVLPY

--------------------------------------------------------------
>60984_60984_3_NUP155-ANKH_NUP155_chr5_37370923_ENST00000513532_ANKH_chr5_14742031_ENST00000284268_length(transcript)=7218nt_BP=261nt
GCGCGCGCGCCCTAGGCGGCGGATCTAAGCTAACTTCTTGGATCTTTTCTTGTTTCTCCTTGGTTTTTGACTTTTTCTGGACCCTGGTGT
CTACGATTTCCGAGATGCCGTCTTCTTTGTTGGGCGCGGCGATGCCGGCCTCTACATCTGCCGCAGCCCTGCAGGAAGCTCTGGAAAATG
CTGGACGGCTCATCGACCGTCAGTTGCAAGAGGACCGCATGTACCCGGACCTTTCCGAGCTGCTTATGGTGTCTGCCCCAAAATAACCCC
AGCAACAAACTGGTGAGCACGAGCAACACAGTCACGGCAGCCCACATCAAGAAGTTCACCTTCGTCTGCATGGCTCTGTCACTCACGCTC
TGTTTCGTGATGTTTTGGACACCCAACGTGTCTGAGAAAATCTTGATAGACATCATCGGAGTGGACTTTGCCTTTGCAGAACTCTGTGTT
GTTCCTTTGCGGATCTTCTCCTTCTTCCCAGTTCCAGTCACAGTGAGGGCGCATCTCACCGGGTGGCTGATGACACTGAAGAAAACCTTC
GTCCTTGCCCCCAGCTCTGTGCTGCGGATCATCGTCCTCATCGCCAGCCTCGTGGTCCTACCCTACCTGGGGGTGCACGGTGCGACCCTG
GGCGTGGGCTCCCTCCTGGCGGGCTTTGTGGGAGAATCCACCATGGTCGCCATCGCTGCGTGCTATGTCTACCGGAAGCAGAAAAAGAAG
ATGGAGAATGAGTCGGCCACGGAGGGGGAAGACTCTGCCATGACAGACATGCCTCCGACAGAGGAGGTGACAGACATCGTGGAAATGAGA
GAGGAGAATGAATAAGGCACGGGACGCCATGGGCACTGCAGGGACAGTCAGTCAGGATGACACTTCGGCATCATCTCTTCCCTCTCCCAT
CGTATTTTGTTCCCTTTTTTTTGTTTTGTTTTGGTAATGAAAGAGGCCTTGATTTAAAGGTTTCGTGTCAATTCTCTAGCATACTGGGTA
TGCTCACACTGACGGGGGGACCTAGTGAATGGTCTTTACTGTTGCTATGTAAAAACAAACGAAACAACTGACTTCATACCCCTGCCTCAC
GAAAACCCAAAAGACACAGCTGCCTCACGGTTGACGTTGTGTCCTCCTCCCCTGGACAATCTCCTCTTGGAACCAAAGGACTGCAGCTGT
GCCATCGCGCCTCGGTCACCCTGCACAGCAGGCCACAGACTCTCCTGTCCCCCTTCATCGCTCTTAAGAATCAACAGGTTAAAACTCGGC
TTCCTTTGATTTGCTTCCCAGTCACATGGCCGTACAAAGAGATGGAGCCCCGGTGGCCTCTTAAATTTCCCTTCCGCCACGGAGTTCGAA
ACCATCTACTCCACACATGCAGGAGGCGGGTGGCACGCTGCAGCCCGGAGTCCCCGTTCACACTGAGGAACGGAGACCTGTGACCACAGC
AGGCTGACAGATGGACAGAATCTCCCGTAGAAAGGTTTGGTTTGAAATGCCCCGGGGGCAGCAAACTGACATGGTTGAATGATAGCATTT
CACTCTGCGTTCTCCTAGATCTGAGCAAGCTGTCAGTTCTCACCCCCACCGTGTATATACATGAGCTAACTTTTTTAAATTGTCACAAAA
GCGCATCTCCAGATTCCAGACCCTGCCGCATGACTTTTCCTGAAGGCTTGCTTTTCCCTCGCCTTTCCTGAAGGTCGCATTAGAGCGAGT
CACATGGAGCATCCTAACTTTGCATTTTAGTTTTTACAGTGAACTGAAGCTTTAAGTCTCATCCAGCATTCTAATGCCAGGTTGCTGTAG
GGTAACTTTTGAAGTAGATATATTACCTGGTTCTGCTATCCTTAGTCATAACTCTGCGGTACAGGTAATTGAGAATGTACTACGGTACTT
CCCTCCCACACCATACGATAAAGCAAGACATTTTATAACGATACCAGAGTCACTATGTGGTCCTCCCTGAAATAACGCATTCGAAATCCA
TGCAGTGCAGTATATTTTTCTAAGTTTTGGAAAGCAGGTTTTTTCCTTTAAAAAAATTATAGACACGGTTCACTAAATTGATTTAGTCAG
AATTCCTAGACTGAAAGAACCTAAAAAAAAAAATATTTTAAAGATATAAATATATGCTGTATATGTTATGTAATTTATTTTAGGCTATAA
TACATTTCCTATTTTCGCATTTTCAATAAAATGTCTCTAATACAATACGGTGATTGCTTGTGTGCTCAACATACCTGCAGTTGAAACGTA
TTGTATCAATGAACATTGTACCTTATTGGCAGCAGTTTTATAAAGTCCGTCATTTGCATTTGAATGTAAGGCTCAGTAAATGACAGAACT
ATTTTTCATTATGGGTAACTGGGGAATAAATGGGTCACTGGAGTAGGAATAGAAGTGCAAGCTGGAAAGGCAAAAATGAGAAAGAAAAAG
GCAGGCCCTTTGTGTCTACCGTTTTCAGTGCTGTGTGATCATATTGTTCCTCACAGCAAAAAAGAATGCAAGGGCATAATGTTAGCTGTG
AACATGCCAGGGTTGCATTCACATTCCTGGGTACCCAGTGCTGATGGGGTGTGCCCACGTGGGGACATGTCCTTGGCGTGCTTCCTCAGA
GTGGCTTTTCCTCCATTAATACATATATGAGTACTGAAAAATTAAGTTGCATAGCTGCTTTGCAGTGGTTTCAGAGGCAGATCTGAGAAG
ATTAAAAAAAAATCTCAATGTATCAGCTTTTTTTAAAGGACATTACTAGAAAATTAAACAGTATTTTTTAACATGTGTGACTTTCATGCT
TCTGGGGTTGGAGCTTAAAGATCCAAACTGAGAAAGCAGGCCGGGCATGGTGGCTCATGCCTGTAATCCCAACACTTTGGGAGGCCAAGG
AGGGTGGATCACTTAAGGTCAGGAGTTTGAGACCAGCCTGGCCAACATGGCAAAACCCTGTCTCTACTAAAAACATAAAAATTAGCTGGG
GGTGGTAGCACATACCTGTAATCCCAGCTACTCAGGAGGCTGAGGCAGGAGAATTTGCTTGATCCTGGGAGGCAGAGGTTGTAGTGAGCC
GAGATCGCGCCATCGCACTCCAGCCTGGGTGACAAGAGCAAAACTCCATCTCAAAAAAAAAAAAAATCCTTTCCCTCTAAATCCAGGAAG
GATCAGCAAGGGCCTCCTCATTATGAGATGAGGAAATACAACTCCAGAGATTCCTTCAGTGATCAAGATCAGTGGGCCATAATATTTGGT
TAGAGTTTCTGAGAACACAGGAAGCAATGCCACACTCAGGCCACCACAATGGAGCTGATTTGGCAGGACTTGTTCAAACCTTTCACCTTA
AAGCACGTGATCCTTCTTCGTACATTTTCTTCACTTGGGCTGCTTAAGTCACAGCCTAACAACTTTGAGGCAAAACTGAGAACTGGCATA
TTCTCCTGCGTTTCTTCTAATCGAGTCCCATCATCCAGCTAGACATGAGAGATCAAACCAGGGAGGGTGACCTTTCTCCTTCCCACTTTT
CAGAGTCATTGGGGCAACTTTTTGACTTTTGTGACCAAAGAAACATTCCCCCAAAACATTTATTTTTCATTGTAGGGCATTCAGCTGACA
GCTGCATTTTAGAAAGTTACCATGCCTGTGAGATTCTCATGTCAAAGACCAGGGAAAGACCAGGTGTGACTTTCTCCAAAACTGAGTGAT
TGCTTGTGGATGAATACAATCTAAAAATACAAGGCCATGAAGTAGTTTTTCATTTAGATGCTGAGAAATAATAGGTTTGGGCAGCTCAAA
GCATAGGAAATAGTAAGGGTTTTCTAGAGCTCCTCCTTTGGTGGCCTGTTTGAGTAGCACAAGGGACGTCATCCTAAATGTGCAGTTGCC
ATTTGTTCTGTAGTGACTTACAGGGATCTCAGTGGCAAAGGGCGTCAGTGAGACAACAACTGAGCAAAAAGAACTAGACGAGGCTTGCGC
TTGGAAAGTCACGGTAGGATTGGACCTGCCGGCCACATGGCTCAGGGAGTATTGACGGATTTGCACATTGGCAGGAAACTCTCCCGTTTG
GGATTCTTTAAATGGGGCACAGAAGGCCACTTGTTTGCATTTCTGGGTAAAAAACAGTCATCCCCCATGACTGCCTGCATCGGGTTTGTC
TTGTGCCAAAGTTACTCTTCCTTTGTTTTTACTTTGCCTTGATTTTTAGCATTAGCTGGTAGTTTGGCTTGGAAATGTCCTGGATAGCCG
ATTCCCTAAGAAACTGAAACATTTAATATTGGCTTAGGATGTATCAGATGGGGCCAAATAAAGCTTCTTTACAATAGTAAAAGCACTTTA
TACTTCACTCTCTGAGTCTTCCCAATAAATAACCTTGGGAGGTGCAGGGGGTGGGGGGCCCAGGATGGGGAGGCCTGGGAGCTCCCAGGG
TAGTGACAGAGTTGGGCTGAGTTCTCCAGACGCCAGGATGCGTCGCAGCGGGGCCAGCTCAGGAGTGCTCACTCCCAGCCCTCTGGATCT
CTCTCCTGGTTGGAATAATCATTACATATCGTAACTCTCAAAATTTATTCACTTATATTTTCAGAATAAGAAGTGTGAAATGTTAACAGC
TCTCTGCTCTCTTACTTGTTCCCCATTTGGGGATCTTCTGGAGGGAAGGGGCAGGGGGAGAGTAACTTTTCTATATCCTTGGTTTCTAGG
AACACATCGATTTGAAGACTCAGTAGCTGACTGGTTTTTTTTTTTCCCCCTTCAAACTGAAGTGCGAGTGTGCGTGTGTTCCACAAAATA
GCAAGTATTTATAGTGTTGTAATTACATTTCCTTGAGAAATATTTTCTTGTATTTAAAAATCTTTCTACTTCAGTAACTCCCAGCAGAAC
AGTGCCCAGGACAGCATGTGCCGGTTAGTACCAGCTTTGCAGGTGAGCTGACTTCTAAACTTAGGACGACGTCTTCATCAATCAAACTAG
TGCACAGTCCAGAAAAAGGGGTCCTTTATCTTCTAAGTTCTGCTCCTCACCTTTCTTTGGAACCAAAATTGCAGTGGAGTGTGAGGAAGA
GCTTTGAAAGACGTGGAGTGTTGAGATGTCTGCATTGCACATTCAGCCGGTTCAAAGCCAGCAGCTCCTGCCTGCATTCTGTAGACATCG
CCCTCACACACAGTCCTCTGATGGCTCTCATATAAAGCACTCAAACCGTAGGAAAGCATGTTTTTGAGCAACGTGTCTGGGATACTCCTC
TGTGTGGTTATTTTGAATCTCTATTTCTGTCATTGAAGCAGCAAAAAACATCATGTGACTCATCAACTGATCTAATCACACTTAAAACAG
GATGTAGAGAAAAATCTGATGAGAAACGTAAAAGGGCCTGTTGCCTGCCCTTTTAAAGGCAAAATGTCTAAAATCATGCAAATGTTCAAA
ATGAGAGAAATTGCATTGTGGAATCAAAATAACCCAAACTCCACTCAGAAAAGTCACAAATATATAGTATACTATCTGATCTCAAAAGGG
AAAAACGAGATGATAAGACCTTAAGTTTAGACTTTATTTTCTTCTCAAGAGTGGACATTAAATCTATTAACTTGCAACTTTCTGCTGGGA
AGAGCATCAAAGGTGGGCCTCCTAAATCATTTTTGAAAAACCTCTGTCAAGTCCAAGTGGTTCCAGGAGAATTATAGCCAGTATCTTTTA
AAATATTTCATTTTAGTGATAATGTTTTTCTCTGCTTCATTTGCAATCAACCAGGATCTCTAAAAGACTGCATAAGATATATGCACTTTT
ATAGGTGGCTGTCAGCTACACATAGATTCAGCAAATTTTTTTTATATAGTACCTGTTTTTAAGTTAGGCTACATAACTTAAAGTGCACTT
TACTAACAAGACTTGACATTAGCGTCTACAATATGTATATGTAAACAAAAGCACACAAGAACTAGGCACCCTTTCTCTCTCCAAGAGTTT
AAGTGGTTTCCTTAGGTTAAAGAAGGGGACAGACCAGCTAAAAATGGTTGTACCACTCACTGTACAACCTCATGGAAATTCTCACTATAA
GATTTAGAGGCAATGTTCCCTAGCTATAAGCCAGGGCAAGAAATGGCGCCTCTGGAGTTGGGGAACATTAGGGGAACATTACAACCGGGT
AGATGCTGGTTCCCTGAAGTGTGGGGCCATGAACATGCAGGGACCCACGGTTTGAATGAAACAGCTACTGAAAGCTAAGTTCAAACCACC
CTTGCGTAACAAAGGAGTACAGGGTACACATCAACACCAATCACCCAGCACCCCACAGCGATGGTCATGTCACCGTGCAGCAGGTCCCTT
ACCCCAGGGCTGCCACATCCACAAGCCTTGCAGTGGCAAATACGCTGCTCCTTGGATTTAATGAGATATTTTGGTTGCTTAATGATGTAC
TGATCAGGGAACTGTCTAAAGCTAGTAGGGCCAAGGAGTTAATCAAAGGGCTTCGGGAAAGTGGACAAGAGCCACACACGTGATTCTGTT
CCATGCCGACACTCATTCATTTAAGAAGTGTATTCAAGCTGGAGGCTTCCATATCACTCACGCTTCTTGGCCTCACCTTGCTCATCTGTC
CAATGGGAGGCTTGAGCCATTATTGCTAAGGCCCCTTCCTGATCTAACATTCTGTTTATGATCTAGGATTTAGAACGTCGTATGAGATCC
TACAATGGAAGAATAAAATCACCTCATTCTTCATTTCAGATCTGAACATTAGCAGTGATCTAGATTTTTTTTTTTTTAAACAAAATTAAG
TGTGCTTAGAGTCATTCCTCTACATGGGCTGTGGCTGTCAGCCCATAGGTTTGTCAGTTTCACATCAAAACTGTGGGTATAAACTGTTGA
AACCAATCACATTAAAATATTTAGCTGGGCACAGTGGTGTGCATCTGTAGTCCCAGCTACTTGGGAGGCTGAGGCAGGAGGATCGCTTAA
GCACAGGAGTTGGAATCCAGCCTGAGCAACAGAGCAAAACCCCGTCTCTAAAATACAAATAAAATATTTGTGTAGTTTTTGATTAAAATT
GACTACAGCGGTCAGTATAAAATACATGTCGCTTTTAAGGAAGTGCTCTTTATGTATCTAACAGATGGAAGTTTTTGCATTGGTAAGAGC
ATTTATATATGCTTTGTTTCAGGGTTTATGGATTTGTATTCATATATTGTCAAATAGGTTTCATACTCTAATTTTACTTTAAGTAAAGCT

>60984_60984_3_NUP155-ANKH_NUP155_chr5_37370923_ENST00000513532_ANKH_chr5_14742031_ENST00000284268_length(amino acids)=252AA_BP=63
MTFSGPWCLRFPRCRLLCWARRCRPLHLPQPCRKLWKMLDGSSTVSCKRTACTRTFPSCLWCLPQNNPSNKLVSTSNTVTAAHIKKFTFV
CMALSLTLCFVMFWTPNVSEKILIDIIGVDFAFAELCVVPLRIFSFFPVPVTVRAHLTGWLMTLKKTFVLAPSSVLRIIVLIASLVVLPY

--------------------------------------------------------------
>60984_60984_4_NUP155-ANKH_NUP155_chr5_37370923_ENST00000513532_ANKH_chr5_14742031_ENST00000535119_length(transcript)=1612nt_BP=261nt
GCGCGCGCGCCCTAGGCGGCGGATCTAAGCTAACTTCTTGGATCTTTTCTTGTTTCTCCTTGGTTTTTGACTTTTTCTGGACCCTGGTGT
CTACGATTTCCGAGATGCCGTCTTCTTTGTTGGGCGCGGCGATGCCGGCCTCTACATCTGCCGCAGCCCTGCAGGAAGCTCTGGAAAATG
CTGGACGGCTCATCGACCGTCAGTTGCAAGAGGACCGCATGTACCCGGACCTTTCCGAGCTGCTTATGGTGTCTGCCCCAAAATAACCCC
AGCAACAAACTGGTGAGCACGAGCAACACAGTCACGGCAGCCCACATCAAGAAGTTCACCTTCGTCTGCATGGCTCTGTCACTCACGCTC
TGTTTCGTGATGTTTTGGACACCCAACGTGTCTGAGAAAATCTTGATAGACATCATCGGAGTGGACTTTGCCTTTGCAGAACTCTGTGTT
GTTCCTTTGCGGATCTTCTCCTTCTTCCCAGTTCCAGTCACAGTGAGGGCGCATCTCACCGGGTGGCTGATGACACTGAAGAAAACCTTC
GTCCTTGCCCCCAGCTCTGTGCTGCGGATCATCGTCCTCATCGCCAGCCTCGTGGTCCTACCCTACCTGGGGGTGCACGGTGCGACCCTG
GGCGTGGGCTCCCTCCTGGCGGGCTTTGTGGGAGAATCCACCATGGTCGCCATCGCTGCGTGCTATGTCTACCGGAAGCAGAAAAAGAAG
ATGGAGAATGAGTCGGCCACGGAGGGGGAAGACTCTGCCATGACAGACATGCCTCCGACAGAGGAGGTGACAGACATCGTGGAAATGAGA
GAGGAGAATGAATAAGGCACGGGACGCCATGGGCACTGCAGGGACAGTCAGTCAGGATGACACTTCGGCATCATCTCTTCCCTCTCCCAT
CGTATTTTGTTCCCTTTTTTTTGTTTTGTTTTGGTAATGAAAGAGGCCTTGATTTAAAGGTTTCGTGTCAATTCTCTAGCATACTGGGTA
TGCCCCTTCCTGATCTAACATTCTGTTTATGATCTAGGATTTAGAACGTCGTATGAGATCCTACAATGGAAGAATAAAATCACCTCATTC
TTCATTTCAGATCTGAACATTAGCAGTGATCTAGATTTTTTTTTTTTTAAACAAAATTAAGTGTGCTTAGAGTCATTCCTCTACATGGGC
TGTGGCTGTCAGCCCATAGGTTTGTCAGTTTCACATCAAAACTGTGGGTATAAACTGTTGAAACCAATCACATTAAAATATTTAGCTGGG
CACAGTGGTGTGCATCTGTAGTCCCAGCTACTTGGGAGGCTGAGGCAGGAGGATCGCTTAAGCACAGGAGTTGGAATCCAGCCTGAGCAA
CAGAGCAAAACCCCGTCTCTAAAATACAAATAAAATATTTGTGTAGTTTTTGATTAAAATTGACTACAGCGGTCAGTATAAAATACATGT
CGCTTTTAAGGAAGTGCTCTTTATGTATCTAACAGATGGAAGTTTTTGCATTGGTAAGAGCATTTATATATGCTTTGTTTCAGGGTTTAT

>60984_60984_4_NUP155-ANKH_NUP155_chr5_37370923_ENST00000513532_ANKH_chr5_14742031_ENST00000535119_length(amino acids)=252AA_BP=63
MTFSGPWCLRFPRCRLLCWARRCRPLHLPQPCRKLWKMLDGSSTVSCKRTACTRTFPSCLWCLPQNNPSNKLVSTSNTVTAAHIKKFTFV
CMALSLTLCFVMFWTPNVSEKILIDIIGVDFAFAELCVVPLRIFSFFPVPVTVRAHLTGWLMTLKKTFVLAPSSVLRIIVLIASLVVLPY

--------------------------------------------------------------

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Fusion Gene PPI Analysis for NUP155-ANKH


check button Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in

ChiPPI page.


check button Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160)
HgeneHgene's interactorsTgeneTgene's interactors


check button - Retained PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenStill interaction with


check button - Lost PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


check button - Retained PPIs, but lost function due to frame-shift fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


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Related Drugs for NUP155-ANKH


check button Drugs targeting genes involved in this fusion gene.
(DrugBank Version 5.1.8 2021-05-08)
PartnerGeneUniProtAccDrugBank IDDrug nameDrug activityDrug typeDrug status

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Related Diseases for NUP155-ANKH


check button Diseases associated with fusion partners.
(DisGeNet 4.0)
PartnerGeneDisease IDDisease name# pubmedsSource