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Center for Computational Systems Medicine
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Fusion Gene Summary

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Fusion Gene ORF analysis

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Fusion Genomic Features

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Fusion Protein Features

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Fusion Gene Sequence

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Fusion Gene PPI analysis

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Related Drugs

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Related Diseases

Fusion gene:NUP98-ADD3 (FusionGDB2 ID:61107)

Fusion Gene Summary for NUP98-ADD3

check button Fusion gene summary
Fusion gene informationFusion gene name: NUP98-ADD3
Fusion gene ID: 61107
HgeneTgene
Gene symbol

NUP98

ADD3

Gene ID

4928

120

Gene namenucleoporin 98 and 96 precursoradducin 3
SynonymsADIR2|NUP196|NUP96|Nup98-96ADDL|CPSQ3
Cytomap

11p15.4

10q25.1-q25.2

Type of geneprotein-codingprotein-coding
Descriptionnuclear pore complex protein Nup98-Nup96nuclear pore complex protein Nup98GLFG-repeat containing nucleoporinNUP98/PHF23 fusion 2 proteinNup98-Nup96nucleoporin 96nucleoporin 98kDnucleoporin 98kDagamma-adducinadducin 3 (gamma)adducin-like protein 70
Modification date2020031320200313
UniProtAcc.

Q9UEY8

Ensembl transtripts involved in fusion geneENST00000324932, ENST00000355260, 
ENST00000359171, ENST00000397004, 
ENST00000397007, ENST00000488828, 
ENST00000497125, ENST00000277900, 
ENST00000356080, ENST00000360162, 
Fusion gene scores* DoF score35 X 37 X 11=1424513 X 11 X 6=858
# samples 3113
** MAII scorelog2(31/14245*10)=-5.52204359593698
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0		log2(13/858*10)=-2.72246602447109
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0
Context

PubMed: NUP98 [Title/Abstract] AND ADD3 [Title/Abstract] AND fusion [Title/Abstract]

Most frequent breakpoint
Anticipated loss of major functional domain due to fusion event.ADD3-NUP98 seems lost the major protein functional domain in Hgene partner, which is a essential gene due to the frame-shifted ORF.
ADD3-NUP98 seems lost the major protein functional domain in Tgene partner, which is a CGC due to the frame-shifted ORF.
ADD3-NUP98 seems lost the major protein functional domain in Tgene partner, which is a essential gene due to the frame-shifted ORF.
ADD3-NUP98 seems lost the major protein functional domain in Tgene partner, which is a tumor suppressor due to the frame-shifted ORF.
NUP98-ADD3 seems lost the major protein functional domain in Hgene partner, which is a CGC due to the frame-shifted ORF.
NUP98-ADD3 seems lost the major protein functional domain in Hgene partner, which is a essential gene due to the frame-shifted ORF.
NUP98-ADD3 seems lost the major protein functional domain in Hgene partner, which is a tumor suppressor due to the frame-shifted ORF.
NUP98-ADD3 seems lost the major protein functional domain in Tgene partner, which is a essential gene due to the frame-shifted ORF.
* DoF score (Degree of Frequency) = # partners X # break points X # cancer types
** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)

check button Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez
PartnerGeneGO IDGO termPubMed ID

check buttonFusion gene breakpoints across NUP98 (5'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.

check buttonFusion gene breakpoints across ADD3 (3'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.

check button Fusion gene information from two resources (ChiTars 5.0 and ChimerDB 4.0)
* All genome coordinats were lifted-over on hg19.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
SourceDiseaseSampleHgeneHchrHbpHstrandTgeneTchrTbpTstrand
ChimerKB3..NUP98chr11

3765738

-ADD3chr10

111893083

+
ChimerKB3..NUP98chr11

3781768

-ADD3chr10

111890120

+


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Fusion Gene ORF analysis for NUP98-ADD3

check button Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
ORFHenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrand
5CDS-intronENST00000324932ENST00000497125NUP98chr11

3765738

-ADD3chr10

111893083

+
5CDS-intronENST00000324932ENST00000497125NUP98chr11

3781768

-ADD3chr10

111890120

+
5CDS-intronENST00000355260ENST00000497125NUP98chr11

3765738

-ADD3chr10

111893083

+
5CDS-intronENST00000355260ENST00000497125NUP98chr11

3781768

-ADD3chr10

111890120

+
5CDS-intronENST00000359171ENST00000497125NUP98chr11

3765738

-ADD3chr10

111893083

+
5CDS-intronENST00000359171ENST00000497125NUP98chr11

3781768

-ADD3chr10

111890120

+
5CDS-intronENST00000397004ENST00000497125NUP98chr11

3765738

-ADD3chr10

111893083

+
5CDS-intronENST00000397004ENST00000497125NUP98chr11

3781768

-ADD3chr10

111890120

+
5CDS-intronENST00000397007ENST00000497125NUP98chr11

3765738

-ADD3chr10

111893083

+
Frame-shiftENST00000324932ENST00000277900NUP98chr11

3765738

-ADD3chr10

111893083

+
Frame-shiftENST00000324932ENST00000277900NUP98chr11

3781768

-ADD3chr10

111890120

+
Frame-shiftENST00000324932ENST00000356080NUP98chr11

3765738

-ADD3chr10

111893083

+
Frame-shiftENST00000324932ENST00000356080NUP98chr11

3781768

-ADD3chr10

111890120

+
Frame-shiftENST00000324932ENST00000360162NUP98chr11

3781768

-ADD3chr10

111890120

+
Frame-shiftENST00000355260ENST00000277900NUP98chr11

3765738

-ADD3chr10

111893083

+
Frame-shiftENST00000355260ENST00000277900NUP98chr11

3781768

-ADD3chr10

111890120

+
Frame-shiftENST00000355260ENST00000356080NUP98chr11

3765738

-ADD3chr10

111893083

+
Frame-shiftENST00000355260ENST00000356080NUP98chr11

3781768

-ADD3chr10

111890120

+
Frame-shiftENST00000355260ENST00000360162NUP98chr11

3781768

-ADD3chr10

111890120

+
Frame-shiftENST00000359171ENST00000277900NUP98chr11

3765738

-ADD3chr10

111893083

+
Frame-shiftENST00000359171ENST00000277900NUP98chr11

3781768

-ADD3chr10

111890120

+
Frame-shiftENST00000359171ENST00000356080NUP98chr11

3765738

-ADD3chr10

111893083

+
Frame-shiftENST00000359171ENST00000356080NUP98chr11

3781768

-ADD3chr10

111890120

+
Frame-shiftENST00000359171ENST00000360162NUP98chr11

3781768

-ADD3chr10

111890120

+
Frame-shiftENST00000397004ENST00000277900NUP98chr11

3765738

-ADD3chr10

111893083

+
Frame-shiftENST00000397004ENST00000277900NUP98chr11

3781768

-ADD3chr10

111890120

+
Frame-shiftENST00000397004ENST00000356080NUP98chr11

3765738

-ADD3chr10

111893083

+
Frame-shiftENST00000397004ENST00000356080NUP98chr11

3781768

-ADD3chr10

111890120

+
Frame-shiftENST00000397004ENST00000360162NUP98chr11

3781768

-ADD3chr10

111890120

+
Frame-shiftENST00000397007ENST00000277900NUP98chr11

3765738

-ADD3chr10

111893083

+
Frame-shiftENST00000397007ENST00000356080NUP98chr11

3765738

-ADD3chr10

111893083

+
In-frameENST00000324932ENST00000360162NUP98chr11

3765738

-ADD3chr10

111893083

+
In-frameENST00000355260ENST00000360162NUP98chr11

3765738

-ADD3chr10

111893083

+
In-frameENST00000359171ENST00000360162NUP98chr11

3765738

-ADD3chr10

111893083

+
In-frameENST00000397004ENST00000360162NUP98chr11

3765738

-ADD3chr10

111893083

+
In-frameENST00000397007ENST00000360162NUP98chr11

3765738

-ADD3chr10

111893083

+
intron-3CDSENST00000397007ENST00000277900NUP98chr11

3781768

-ADD3chr10

111890120

+
intron-3CDSENST00000397007ENST00000356080NUP98chr11

3781768

-ADD3chr10

111890120

+
intron-3CDSENST00000397007ENST00000360162NUP98chr11

3781768

-ADD3chr10

111890120

+
intron-3CDSENST00000488828ENST00000277900NUP98chr11

3765738

-ADD3chr10

111893083

+
intron-3CDSENST00000488828ENST00000277900NUP98chr11

3781768

-ADD3chr10

111890120

+
intron-3CDSENST00000488828ENST00000356080NUP98chr11

3765738

-ADD3chr10

111893083

+
intron-3CDSENST00000488828ENST00000356080NUP98chr11

3781768

-ADD3chr10

111890120

+
intron-3CDSENST00000488828ENST00000360162NUP98chr11

3765738

-ADD3chr10

111893083

+
intron-3CDSENST00000488828ENST00000360162NUP98chr11

3781768

-ADD3chr10

111890120

+
intron-intronENST00000397007ENST00000497125NUP98chr11

3781768

-ADD3chr10

111890120

+
intron-intronENST00000488828ENST00000497125NUP98chr11

3765738

-ADD3chr10

111893083

+
intron-intronENST00000488828ENST00000497125NUP98chr11

3781768

-ADD3chr10

111890120

+

check buttonORFfinder result based on the fusion transcript sequence of in-frame fusion genes.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandSeq length
(transcript)		BP loci
(transcript)		Predicted start
(transcript)		Predicted stop
(transcript)		Seq length
(amino acids)
ENST00000324932NUP98chr113765738-ENST00000360162ADD3chr10111893083+283418293972121574
ENST00000359171NUP98chr113765738-ENST00000360162ADD3chr10111893083+283418293972121574
ENST00000355260NUP98chr113765738-ENST00000360162ADD3chr10111893083+25001495631787574
ENST00000397004NUP98chr113765738-ENST00000360162ADD3chr10111893083+258315781461870574
ENST00000397007NUP98chr113765738-ENST00000360162ADD3chr10111893083+264016351521927591

check buttonDeepORF prediction of the coding potential based on the fusion transcript sequence of in-frame fusion genes. DeepORF is a coding potential classifier based on convolutional neural network by comparing the real Ribo-seq data. If the no-coding score < 0.5 and coding score > 0.5, then the in-frame fusion transcript is predicted as being likely translated.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandNo-coding scoreCoding score

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Fusion Genomic Features for NUP98-ADD3


check buttonFusionAI prediction of the potential fusion gene breakpoint based on the pre-mature RNA sequence context (+/- 5kb of individual partner genes, total 20kb length sequence). FusionAI is a fusion gene breakpoint classifier based on convolutional neural network by comparing the fusion positive and negative sequence context of ~ 20K fusion gene data. From here, we can have the relative potentency of the 20K genomic sequence how individual sequnce will be likely used as the gene fusion breakpoints.
HgeneHchrHbpHstrandTgeneTchrTbpTstrand1-pp (fusion gene breakpoint)

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions. We integrated a total of 44 different types of human genomic feature loci information across five big categories including virus integration sites, repeats, structural variants, chromatin states, and gene expression regulation. More details are in help page.

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions that are ovelapped with the top 1% feature importance score regions. More details are in help page.

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Fusion Protein Features for NUP98-ADD3


check button Four levels of functional features of fusion genes
Go to FGviewer search page for the most frequent breakpoint (https://ccsmweb.uth.edu/FGviewer/chr11:/chr10:)
- FGviewer provides the online visualization of the retention search of the protein functional features across DNA, RNA, protein, and pathological levels.
- How to search
1. Put your fusion gene symbol.
2. Press the tab key until there will be shown the breakpoint information filled.
4. Go down and press 'Search' tab twice.
4. Go down to have the hyperlink of the search result.
5. Click the hyperlink.
6. See the FGviewer result for your fusion gene.
FGviewer

check buttonMain function of each fusion partner protein. (from UniProt)
HgeneTgene
.ADD3

Q9UEY8

FUNCTION: Transcriptional activator which is required for calcium-dependent dendritic growth and branching in cortical neurons. Recruits CREB-binding protein (CREBBP) to nuclear bodies. Component of the CREST-BRG1 complex, a multiprotein complex that regulates promoter activation by orchestrating a calcium-dependent release of a repressor complex and a recruitment of an activator complex. In resting neurons, transcription of the c-FOS promoter is inhibited by BRG1-dependent recruitment of a phospho-RB1-HDAC1 repressor complex. Upon calcium influx, RB1 is dephosphorylated by calcineurin, which leads to release of the repressor complex. At the same time, there is increased recruitment of CREBBP to the promoter by a CREST-dependent mechanism, which leads to transcriptional activation. The CREST-BRG1 complex also binds to the NR2B promoter, and activity-dependent induction of NR2B expression involves a release of HDAC1 and recruitment of CREBBP (By similarity). {ECO:0000250}.FUNCTION: Membrane-cytoskeleton-associated protein that promotes the assembly of the spectrin-actin network. Plays a role in actin filament capping (PubMed:23836506). Binds to calmodulin. {ECO:0000269|PubMed:23836506}.

check buttonRetention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at

download page


* Minus value of BPloci means that the break pointn is located before the CDS.
- In-frame and retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note

- In-frame and not-retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note


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Fusion Gene Sequence for NUP98-ADD3


check button For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. To have fusion amino acid sequence, we ran ORFfinder and chose the longest ORF among the all predicted ones.
>61107_61107_1_NUP98-ADD3_NUP98_chr11_3765738_ENST00000324932_ADD3_chr10_111893083_ENST00000360162_length(transcript)=2834nt_BP=1829nt
AACCGCGGCGGCGAGGGGCGGGACTCCACGGCCCTCTCACCGCTCCTACCCTGTGCCTCCCCGAACTCCTTCTGCCCCTCCTCTTCCCTC
TCGCCCCTTCCCCCTTCAGTTCGGTTTCAAAAGACGCGTTGCCCAATGAATAACAGGGTCGACCCAGAGTGGCGGCCGCGTCCACCAATT
CGCGGACGGCGAGGGCGGAGCGTCCGCAACGAGCCTCTGACGCCGGGCGGCGTGTGACGCAGTCGGGCCCTCTGCGCGCTGCGCCCGAAG
CGGCGGTCGGTGGCAGGGGTGGTAGCGGCGGCGGCGACGGTTTCGTGGGGGCCGCGCGCTGCTCTGTGAGCGGCGGGTGGCAGCAGGGGA
CTCCTGACACTTCCCCTTCCCCACCGAACCGCGCTTTCTGAAACAAAGACTCATTTTGAAGATGTTTAACAAATCATTTGGAACACCCTT
TGGGGGTGGCACAGGTGGCTTTGGCACAACTTCAACATTTGGACAGAATACTGGCTTTGGCACTACTAGTGGAGGGGCATTTGGAACATC
TGCATTTGGTTCTAGCAACAATACTGGAGGCCTCTTTGGAAATTCACAGACTAAACCAGGAGGATTGTTTGGAACCAGTTCATTTAGCCA
GCCAGCTACCTCCACAAGCACTGGCTTTGGGTTTGGTACGTCAACAGGAACAGCAAATACCTTGTTTGGAACTGCAAGCACAGGGACCAG
TCTCTTCTCATCCCAAAACAATGCCTTTGCACAAAATAAACCAACTGGCTTTGGCAATTTTGGAACCAGTACTAGCAGTGGAGGACTCTT
TGGAACCACAAATACCACCTCTAATCCTTTTGGCAGCACATCTGGCTCCCTCTTTGGGCCAAGTAGTTTTACAGCTGCTCCTACTGGGAC
TACTATTAAATTTAACCCTCCAACTGGTACAGATACTATGGTCAAAGCTGGAGTTAGCACTAACATAAGTACCAAGCACCAGTGTATTAC
TGCTATGAAAGAATATGAAAGCAAGTCACTAGAGGAACTTCGTTTAGAGGATTATCAGGCTAACAGGAAGGGCCCACAGAACCAGGTGGG
AGCAGGTACCACAACTGGCTTGTTTGGGTCTTCTCCAGCCACTTCCAGCGCAACAGGACTCTTCAGCTCCTCCACCACTAATTCAGGCTT
TGCATATGGTCAGAACAAAACTGCCTTTGGAACTAGTACAACTGGATTTGGAACAAATCCAGGTGGTCTCTTTGGCCAACAGAATCAGCA
GACTACCAGCCTCTTCAGCAAACCATTTGGCCAGGCTACAACCACCCAGAACACTGGCTTTTCCTTTGGTAATACCAGCACCATAGGACA
GCCAAGCACCAACACCATGGGATTATTTGGAGTAACCCAAGCCTCACAGCCTGGAGGTCTTTTTGGGACAGCTACAAACACCAGCACTGG
GACAGCATTTGGAACAGGAACAGGTCTCTTTGGGCAGACCAATACTGGATTTGGTGCTGTTGGTTCGACCCTGTTTGGCAATAACAAGCT
TACTACATTTGGAAGCAGCACAACCAGTGCACCTTCATTTGGTACAACCAGTGGCGGGCTCTTTGGTTTTGGCACAAATACCAGTGGGAA
TAGTATTTTTGGAAGTAAACCAGCACCTGGGACTCTTGGAACTGGGCTTGGTGCAGGATTTGGAACAGCTCTTGGTGCTGGACAGGCATC
TTTGTTTGGGAACAACCAACCTAAGATTGGAGGGCCTCTTGGTACAGGAGCCTTTGGGGCCCCTGGATTTAATACTACGACAGCCACTTT
GGGCTTTGGAGCCCCCCAGGCCCCAGTAGAAAACCATGAGCTGTTTTCCAAGAGCTTCATCTCCATGGAAGTGCCTGTCATGGTAGTAAA
TGGCAAGGATGATATGCATGATGTTGAAGATGAGCTTGCTAAGCGAGTGAGTAGGTTAAGCACAAGTACAACCATAGAAAACATCGAGAT
TACTATTAAGTCTCCAGAGAAAATCGAAGAAGTCCTGTCACCTGAAGGCTCCCCTTCAAAATCGCCATCCAAGAAAAAGAAGAAATTCCG
CACTCCTTCTTTTCTGAAAAAGAACAAAAAAAAGGAGAAAGTTGAGGCCTAAATAAAGTCTTTTTATAATTATTATTATAACAATGTGAC
ATTGCACATCTAAATACCACATTTAAGTTGATCATTAATATGCAATGGTAGATCAGATTGGGGGATGTAGCAAACTGGACTTTAAGAACT
GGAAAGAGGTTTTACAAAAGAAAAACTTTCAGATTCATCTCTCATTTTATATGTCCAGAAATGGCTTTGAATTTTAAGCAATTACTAGTT
TTAATTAGCTCTGCCCTCATGAAGTATTATTATAATTCACCATAAACAGCTATCTGTCTGAATTACTTCAGGCCTTCTCCATAATATCTG
TTAGAAAGAAATTGCCAGTGAGCAAGTGAGAATTTTTATTTCTCAATACCTGCTTCACTTGATAATCATATTATAATTTTTTATCATGAT
TATTGACTATATTTTTGGAGTCCCATTGTTTCAGTGGGCATTAACAGAATGCTTTAAAAACTTCTAAGACAAGAATCTATAGCATTAGTA
TACACTGGCACATAATTTTTTAAAAAGTTTTAAGAAAAGATTCATTTGGAATTTTATTCACAGTATAAAATTTCCTCACCTGAAGTAACT
TTGTTTGCCAAAAAAGTTGTTTTAATAAACTATAATTTTTGAAAACTTCCTTTTTTATTAGTTTAGAAAGCCCCTTATTTTTCAACAAAG

>61107_61107_1_NUP98-ADD3_NUP98_chr11_3765738_ENST00000324932_ADD3_chr10_111893083_ENST00000360162_length(amino acids)=574AA_BP=476
MKQRLILKMFNKSFGTPFGGGTGGFGTTSTFGQNTGFGTTSGGAFGTSAFGSSNNTGGLFGNSQTKPGGLFGTSSFSQPATSTSTGFGFG
TSTGTANTLFGTASTGTSLFSSQNNAFAQNKPTGFGNFGTSTSSGGLFGTTNTTSNPFGSTSGSLFGPSSFTAAPTGTTIKFNPPTGTDT
MVKAGVSTNISTKHQCITAMKEYESKSLEELRLEDYQANRKGPQNQVGAGTTTGLFGSSPATSSATGLFSSSTTNSGFAYGQNKTAFGTS
TTGFGTNPGGLFGQQNQQTTSLFSKPFGQATTTQNTGFSFGNTSTIGQPSTNTMGLFGVTQASQPGGLFGTATNTSTGTAFGTGTGLFGQ
TNTGFGAVGSTLFGNNKLTTFGSSTTSAPSFGTTSGGLFGFGTNTSGNSIFGSKPAPGTLGTGLGAGFGTALGAGQASLFGNNQPKIGGP
LGTGAFGAPGFNTTTATLGFGAPQAPVENHELFSKSFISMEVPVMVVNGKDDMHDVEDELAKRVSRLSTSTTIENIEITIKSPEKIEEVL

--------------------------------------------------------------
>61107_61107_2_NUP98-ADD3_NUP98_chr11_3765738_ENST00000355260_ADD3_chr10_111893083_ENST00000360162_length(transcript)=2500nt_BP=1495nt
TGTGAGCGGCGGGTGGCAGCAGGGGACTCCTGACACTTCCCCTTCCCCACCGAACCGCGCTTTCTGAAACAAAGACTCATTTTGAAGATG
TTTAACAAATCATTTGGAACACCCTTTGGGGGTGGCACAGGTGGCTTTGGCACAACTTCAACATTTGGACAGAATACTGGCTTTGGCACT
ACTAGTGGAGGGGCATTTGGAACATCTGCATTTGGTTCTAGCAACAATACTGGAGGCCTCTTTGGAAATTCACAGACTAAACCAGGAGGA
TTGTTTGGAACCAGTTCATTTAGCCAGCCAGCTACCTCCACAAGCACTGGCTTTGGGTTTGGTACGTCAACAGGAACAGCAAATACCTTG
TTTGGAACTGCAAGCACAGGGACCAGTCTCTTCTCATCCCAAAACAATGCCTTTGCACAAAATAAACCAACTGGCTTTGGCAATTTTGGA
ACCAGTACTAGCAGTGGAGGACTCTTTGGAACCACAAATACCACCTCTAATCCTTTTGGCAGCACATCTGGCTCCCTCTTTGGGCCAAGT
AGTTTTACAGCTGCTCCTACTGGGACTACTATTAAATTTAACCCTCCAACTGGTACAGATACTATGGTCAAAGCTGGAGTTAGCACTAAC
ATAAGTACCAAGCACCAGTGTATTACTGCTATGAAAGAATATGAAAGCAAGTCACTAGAGGAACTTCGTTTAGAGGATTATCAGGCTAAC
AGGAAGGGCCCACAGAACCAGGTGGGAGCAGGTACCACAACTGGCTTGTTTGGGTCTTCTCCAGCCACTTCCAGCGCAACAGGACTCTTC
AGCTCCTCCACCACTAATTCAGGCTTTGCATATGGTCAGAACAAAACTGCCTTTGGAACTAGTACAACTGGATTTGGAACAAATCCAGGT
GGTCTCTTTGGCCAACAGAATCAGCAGACTACCAGCCTCTTCAGCAAACCATTTGGCCAGGCTACAACCACCCAGAACACTGGCTTTTCC
TTTGGTAATACCAGCACCATAGGACAGCCAAGCACCAACACCATGGGATTATTTGGAGTAACCCAAGCCTCACAGCCTGGAGGTCTTTTT
GGGACAGCTACAAACACCAGCACTGGGACAGCATTTGGAACAGGAACAGGTCTCTTTGGGCAGACCAATACTGGATTTGGTGCTGTTGGT
TCGACCCTGTTTGGCAATAACAAGCTTACTACATTTGGAAGCAGCACAACCAGTGCACCTTCATTTGGTACAACCAGTGGCGGGCTCTTT
GGTTTTGGCACAAATACCAGTGGGAATAGTATTTTTGGAAGTAAACCAGCACCTGGGACTCTTGGAACTGGGCTTGGTGCAGGATTTGGA
ACAGCTCTTGGTGCTGGACAGGCATCTTTGTTTGGGAACAACCAACCTAAGATTGGAGGGCCTCTTGGTACAGGAGCCTTTGGGGCCCCT
GGATTTAATACTACGACAGCCACTTTGGGCTTTGGAGCCCCCCAGGCCCCAGTAGAAAACCATGAGCTGTTTTCCAAGAGCTTCATCTCC
ATGGAAGTGCCTGTCATGGTAGTAAATGGCAAGGATGATATGCATGATGTTGAAGATGAGCTTGCTAAGCGAGTGAGTAGGTTAAGCACA
AGTACAACCATAGAAAACATCGAGATTACTATTAAGTCTCCAGAGAAAATCGAAGAAGTCCTGTCACCTGAAGGCTCCCCTTCAAAATCG
CCATCCAAGAAAAAGAAGAAATTCCGCACTCCTTCTTTTCTGAAAAAGAACAAAAAAAAGGAGAAAGTTGAGGCCTAAATAAAGTCTTTT
TATAATTATTATTATAACAATGTGACATTGCACATCTAAATACCACATTTAAGTTGATCATTAATATGCAATGGTAGATCAGATTGGGGG
ATGTAGCAAACTGGACTTTAAGAACTGGAAAGAGGTTTTACAAAAGAAAAACTTTCAGATTCATCTCTCATTTTATATGTCCAGAAATGG
CTTTGAATTTTAAGCAATTACTAGTTTTAATTAGCTCTGCCCTCATGAAGTATTATTATAATTCACCATAAACAGCTATCTGTCTGAATT
ACTTCAGGCCTTCTCCATAATATCTGTTAGAAAGAAATTGCCAGTGAGCAAGTGAGAATTTTTATTTCTCAATACCTGCTTCACTTGATA
ATCATATTATAATTTTTTATCATGATTATTGACTATATTTTTGGAGTCCCATTGTTTCAGTGGGCATTAACAGAATGCTTTAAAAACTTC
TAAGACAAGAATCTATAGCATTAGTATACACTGGCACATAATTTTTTAAAAAGTTTTAAGAAAAGATTCATTTGGAATTTTATTCACAGT
ATAAAATTTCCTCACCTGAAGTAACTTTGTTTGCCAAAAAAGTTGTTTTAATAAACTATAATTTTTGAAAACTTCCTTTTTTATTAGTTT

>61107_61107_2_NUP98-ADD3_NUP98_chr11_3765738_ENST00000355260_ADD3_chr10_111893083_ENST00000360162_length(amino acids)=574AA_BP=476
MKQRLILKMFNKSFGTPFGGGTGGFGTTSTFGQNTGFGTTSGGAFGTSAFGSSNNTGGLFGNSQTKPGGLFGTSSFSQPATSTSTGFGFG
TSTGTANTLFGTASTGTSLFSSQNNAFAQNKPTGFGNFGTSTSSGGLFGTTNTTSNPFGSTSGSLFGPSSFTAAPTGTTIKFNPPTGTDT
MVKAGVSTNISTKHQCITAMKEYESKSLEELRLEDYQANRKGPQNQVGAGTTTGLFGSSPATSSATGLFSSSTTNSGFAYGQNKTAFGTS
TTGFGTNPGGLFGQQNQQTTSLFSKPFGQATTTQNTGFSFGNTSTIGQPSTNTMGLFGVTQASQPGGLFGTATNTSTGTAFGTGTGLFGQ
TNTGFGAVGSTLFGNNKLTTFGSSTTSAPSFGTTSGGLFGFGTNTSGNSIFGSKPAPGTLGTGLGAGFGTALGAGQASLFGNNQPKIGGP
LGTGAFGAPGFNTTTATLGFGAPQAPVENHELFSKSFISMEVPVMVVNGKDDMHDVEDELAKRVSRLSTSTTIENIEITIKSPEKIEEVL

--------------------------------------------------------------
>61107_61107_3_NUP98-ADD3_NUP98_chr11_3765738_ENST00000359171_ADD3_chr10_111893083_ENST00000360162_length(transcript)=2834nt_BP=1829nt
AACCGCGGCGGCGAGGGGCGGGACTCCACGGCCCTCTCACCGCTCCTACCCTGTGCCTCCCCGAACTCCTTCTGCCCCTCCTCTTCCCTC
TCGCCCCTTCCCCCTTCAGTTCGGTTTCAAAAGACGCGTTGCCCAATGAATAACAGGGTCGACCCAGAGTGGCGGCCGCGTCCACCAATT
CGCGGACGGCGAGGGCGGAGCGTCCGCAACGAGCCTCTGACGCCGGGCGGCGTGTGACGCAGTCGGGCCCTCTGCGCGCTGCGCCCGAAG
CGGCGGTCGGTGGCAGGGGTGGTAGCGGCGGCGGCGACGGTTTCGTGGGGGCCGCGCGCTGCTCTGTGAGCGGCGGGTGGCAGCAGGGGA
CTCCTGACACTTCCCCTTCCCCACCGAACCGCGCTTTCTGAAACAAAGACTCATTTTGAAGATGTTTAACAAATCATTTGGAACACCCTT
TGGGGGTGGCACAGGTGGCTTTGGCACAACTTCAACATTTGGACAGAATACTGGCTTTGGCACTACTAGTGGAGGGGCATTTGGAACATC
TGCATTTGGTTCTAGCAACAATACTGGAGGCCTCTTTGGAAATTCACAGACTAAACCAGGAGGATTGTTTGGAACCAGTTCATTTAGCCA
GCCAGCTACCTCCACAAGCACTGGCTTTGGGTTTGGTACGTCAACAGGAACAGCAAATACCTTGTTTGGAACTGCAAGCACAGGGACCAG
TCTCTTCTCATCCCAAAACAATGCCTTTGCACAAAATAAACCAACTGGCTTTGGCAATTTTGGAACCAGTACTAGCAGTGGAGGACTCTT
TGGAACCACAAATACCACCTCTAATCCTTTTGGCAGCACATCTGGCTCCCTCTTTGGGCCAAGTAGTTTTACAGCTGCTCCTACTGGGAC
TACTATTAAATTTAACCCTCCAACTGGTACAGATACTATGGTCAAAGCTGGAGTTAGCACTAACATAAGTACCAAGCACCAGTGTATTAC
TGCTATGAAAGAATATGAAAGCAAGTCACTAGAGGAACTTCGTTTAGAGGATTATCAGGCTAACAGGAAGGGCCCACAGAACCAGGTGGG
AGCAGGTACCACAACTGGCTTGTTTGGGTCTTCTCCAGCCACTTCCAGCGCAACAGGACTCTTCAGCTCCTCCACCACTAATTCAGGCTT
TGCATATGGTCAGAACAAAACTGCCTTTGGAACTAGTACAACTGGATTTGGAACAAATCCAGGTGGTCTCTTTGGCCAACAGAATCAGCA
GACTACCAGCCTCTTCAGCAAACCATTTGGCCAGGCTACAACCACCCAGAACACTGGCTTTTCCTTTGGTAATACCAGCACCATAGGACA
GCCAAGCACCAACACCATGGGATTATTTGGAGTAACCCAAGCCTCACAGCCTGGAGGTCTTTTTGGGACAGCTACAAACACCAGCACTGG
GACAGCATTTGGAACAGGAACAGGTCTCTTTGGGCAGACCAATACTGGATTTGGTGCTGTTGGTTCGACCCTGTTTGGCAATAACAAGCT
TACTACATTTGGAAGCAGCACAACCAGTGCACCTTCATTTGGTACAACCAGTGGCGGGCTCTTTGGTTTTGGCACAAATACCAGTGGGAA
TAGTATTTTTGGAAGTAAACCAGCACCTGGGACTCTTGGAACTGGGCTTGGTGCAGGATTTGGAACAGCTCTTGGTGCTGGACAGGCATC
TTTGTTTGGGAACAACCAACCTAAGATTGGAGGGCCTCTTGGTACAGGAGCCTTTGGGGCCCCTGGATTTAATACTACGACAGCCACTTT
GGGCTTTGGAGCCCCCCAGGCCCCAGTAGAAAACCATGAGCTGTTTTCCAAGAGCTTCATCTCCATGGAAGTGCCTGTCATGGTAGTAAA
TGGCAAGGATGATATGCATGATGTTGAAGATGAGCTTGCTAAGCGAGTGAGTAGGTTAAGCACAAGTACAACCATAGAAAACATCGAGAT
TACTATTAAGTCTCCAGAGAAAATCGAAGAAGTCCTGTCACCTGAAGGCTCCCCTTCAAAATCGCCATCCAAGAAAAAGAAGAAATTCCG
CACTCCTTCTTTTCTGAAAAAGAACAAAAAAAAGGAGAAAGTTGAGGCCTAAATAAAGTCTTTTTATAATTATTATTATAACAATGTGAC
ATTGCACATCTAAATACCACATTTAAGTTGATCATTAATATGCAATGGTAGATCAGATTGGGGGATGTAGCAAACTGGACTTTAAGAACT
GGAAAGAGGTTTTACAAAAGAAAAACTTTCAGATTCATCTCTCATTTTATATGTCCAGAAATGGCTTTGAATTTTAAGCAATTACTAGTT
TTAATTAGCTCTGCCCTCATGAAGTATTATTATAATTCACCATAAACAGCTATCTGTCTGAATTACTTCAGGCCTTCTCCATAATATCTG
TTAGAAAGAAATTGCCAGTGAGCAAGTGAGAATTTTTATTTCTCAATACCTGCTTCACTTGATAATCATATTATAATTTTTTATCATGAT
TATTGACTATATTTTTGGAGTCCCATTGTTTCAGTGGGCATTAACAGAATGCTTTAAAAACTTCTAAGACAAGAATCTATAGCATTAGTA
TACACTGGCACATAATTTTTTAAAAAGTTTTAAGAAAAGATTCATTTGGAATTTTATTCACAGTATAAAATTTCCTCACCTGAAGTAACT
TTGTTTGCCAAAAAAGTTGTTTTAATAAACTATAATTTTTGAAAACTTCCTTTTTTATTAGTTTAGAAAGCCCCTTATTTTTCAACAAAG

>61107_61107_3_NUP98-ADD3_NUP98_chr11_3765738_ENST00000359171_ADD3_chr10_111893083_ENST00000360162_length(amino acids)=574AA_BP=476
MKQRLILKMFNKSFGTPFGGGTGGFGTTSTFGQNTGFGTTSGGAFGTSAFGSSNNTGGLFGNSQTKPGGLFGTSSFSQPATSTSTGFGFG
TSTGTANTLFGTASTGTSLFSSQNNAFAQNKPTGFGNFGTSTSSGGLFGTTNTTSNPFGSTSGSLFGPSSFTAAPTGTTIKFNPPTGTDT
MVKAGVSTNISTKHQCITAMKEYESKSLEELRLEDYQANRKGPQNQVGAGTTTGLFGSSPATSSATGLFSSSTTNSGFAYGQNKTAFGTS
TTGFGTNPGGLFGQQNQQTTSLFSKPFGQATTTQNTGFSFGNTSTIGQPSTNTMGLFGVTQASQPGGLFGTATNTSTGTAFGTGTGLFGQ
TNTGFGAVGSTLFGNNKLTTFGSSTTSAPSFGTTSGGLFGFGTNTSGNSIFGSKPAPGTLGTGLGAGFGTALGAGQASLFGNNQPKIGGP
LGTGAFGAPGFNTTTATLGFGAPQAPVENHELFSKSFISMEVPVMVVNGKDDMHDVEDELAKRVSRLSTSTTIENIEITIKSPEKIEEVL

--------------------------------------------------------------
>61107_61107_4_NUP98-ADD3_NUP98_chr11_3765738_ENST00000397004_ADD3_chr10_111893083_ENST00000360162_length(transcript)=2583nt_BP=1578nt
CTGCGCGCTGCGCCCGAAGCGGCGGTCGGTGGCAGGGGTGGTAGCGGCGGCGGCGACGGTTTCGTGGGGGCCGCGCGCTGCTCTGTGAGC
GGCGGGTGGCAGCAGGGGACTCCTGACACTTCCCCTTCCCCACCGAACCGCGCTTTCTGAAACAAAGACTCATTTTGAAGATGTTTAACA
AATCATTTGGAACACCCTTTGGGGGTGGCACAGGTGGCTTTGGCACAACTTCAACATTTGGACAGAATACTGGCTTTGGCACTACTAGTG
GAGGGGCATTTGGAACATCTGCATTTGGTTCTAGCAACAATACTGGAGGCCTCTTTGGAAATTCACAGACTAAACCAGGAGGATTGTTTG
GAACCAGTTCATTTAGCCAGCCAGCTACCTCCACAAGCACTGGCTTTGGGTTTGGTACGTCAACAGGAACAGCAAATACCTTGTTTGGAA
CTGCAAGCACAGGGACCAGTCTCTTCTCATCCCAAAACAATGCCTTTGCACAAAATAAACCAACTGGCTTTGGCAATTTTGGAACCAGTA
CTAGCAGTGGAGGACTCTTTGGAACCACAAATACCACCTCTAATCCTTTTGGCAGCACATCTGGCTCCCTCTTTGGGCCAAGTAGTTTTA
CAGCTGCTCCTACTGGGACTACTATTAAATTTAACCCTCCAACTGGTACAGATACTATGGTCAAAGCTGGAGTTAGCACTAACATAAGTA
CCAAGCACCAGTGTATTACTGCTATGAAAGAATATGAAAGCAAGTCACTAGAGGAACTTCGTTTAGAGGATTATCAGGCTAACAGGAAGG
GCCCACAGAACCAGGTGGGAGCAGGTACCACAACTGGCTTGTTTGGGTCTTCTCCAGCCACTTCCAGCGCAACAGGACTCTTCAGCTCCT
CCACCACTAATTCAGGCTTTGCATATGGTCAGAACAAAACTGCCTTTGGAACTAGTACAACTGGATTTGGAACAAATCCAGGTGGTCTCT
TTGGCCAACAGAATCAGCAGACTACCAGCCTCTTCAGCAAACCATTTGGCCAGGCTACAACCACCCAGAACACTGGCTTTTCCTTTGGTA
ATACCAGCACCATAGGACAGCCAAGCACCAACACCATGGGATTATTTGGAGTAACCCAAGCCTCACAGCCTGGAGGTCTTTTTGGGACAG
CTACAAACACCAGCACTGGGACAGCATTTGGAACAGGAACAGGTCTCTTTGGGCAGACCAATACTGGATTTGGTGCTGTTGGTTCGACCC
TGTTTGGCAATAACAAGCTTACTACATTTGGAAGCAGCACAACCAGTGCACCTTCATTTGGTACAACCAGTGGCGGGCTCTTTGGTTTTG
GCACAAATACCAGTGGGAATAGTATTTTTGGAAGTAAACCAGCACCTGGGACTCTTGGAACTGGGCTTGGTGCAGGATTTGGAACAGCTC
TTGGTGCTGGACAGGCATCTTTGTTTGGGAACAACCAACCTAAGATTGGAGGGCCTCTTGGTACAGGAGCCTTTGGGGCCCCTGGATTTA
ATACTACGACAGCCACTTTGGGCTTTGGAGCCCCCCAGGCCCCAGTAGAAAACCATGAGCTGTTTTCCAAGAGCTTCATCTCCATGGAAG
TGCCTGTCATGGTAGTAAATGGCAAGGATGATATGCATGATGTTGAAGATGAGCTTGCTAAGCGAGTGAGTAGGTTAAGCACAAGTACAA
CCATAGAAAACATCGAGATTACTATTAAGTCTCCAGAGAAAATCGAAGAAGTCCTGTCACCTGAAGGCTCCCCTTCAAAATCGCCATCCA
AGAAAAAGAAGAAATTCCGCACTCCTTCTTTTCTGAAAAAGAACAAAAAAAAGGAGAAAGTTGAGGCCTAAATAAAGTCTTTTTATAATT
ATTATTATAACAATGTGACATTGCACATCTAAATACCACATTTAAGTTGATCATTAATATGCAATGGTAGATCAGATTGGGGGATGTAGC
AAACTGGACTTTAAGAACTGGAAAGAGGTTTTACAAAAGAAAAACTTTCAGATTCATCTCTCATTTTATATGTCCAGAAATGGCTTTGAA
TTTTAAGCAATTACTAGTTTTAATTAGCTCTGCCCTCATGAAGTATTATTATAATTCACCATAAACAGCTATCTGTCTGAATTACTTCAG
GCCTTCTCCATAATATCTGTTAGAAAGAAATTGCCAGTGAGCAAGTGAGAATTTTTATTTCTCAATACCTGCTTCACTTGATAATCATAT
TATAATTTTTTATCATGATTATTGACTATATTTTTGGAGTCCCATTGTTTCAGTGGGCATTAACAGAATGCTTTAAAAACTTCTAAGACA
AGAATCTATAGCATTAGTATACACTGGCACATAATTTTTTAAAAAGTTTTAAGAAAAGATTCATTTGGAATTTTATTCACAGTATAAAAT
TTCCTCACCTGAAGTAACTTTGTTTGCCAAAAAAGTTGTTTTAATAAACTATAATTTTTGAAAACTTCCTTTTTTATTAGTTTAGAAAGC

>61107_61107_4_NUP98-ADD3_NUP98_chr11_3765738_ENST00000397004_ADD3_chr10_111893083_ENST00000360162_length(amino acids)=574AA_BP=476
MKQRLILKMFNKSFGTPFGGGTGGFGTTSTFGQNTGFGTTSGGAFGTSAFGSSNNTGGLFGNSQTKPGGLFGTSSFSQPATSTSTGFGFG
TSTGTANTLFGTASTGTSLFSSQNNAFAQNKPTGFGNFGTSTSSGGLFGTTNTTSNPFGSTSGSLFGPSSFTAAPTGTTIKFNPPTGTDT
MVKAGVSTNISTKHQCITAMKEYESKSLEELRLEDYQANRKGPQNQVGAGTTTGLFGSSPATSSATGLFSSSTTNSGFAYGQNKTAFGTS
TTGFGTNPGGLFGQQNQQTTSLFSKPFGQATTTQNTGFSFGNTSTIGQPSTNTMGLFGVTQASQPGGLFGTATNTSTGTAFGTGTGLFGQ
TNTGFGAVGSTLFGNNKLTTFGSSTTSAPSFGTTSGGLFGFGTNTSGNSIFGSKPAPGTLGTGLGAGFGTALGAGQASLFGNNQPKIGGP
LGTGAFGAPGFNTTTATLGFGAPQAPVENHELFSKSFISMEVPVMVVNGKDDMHDVEDELAKRVSRLSTSTTIENIEITIKSPEKIEEVL

--------------------------------------------------------------
>61107_61107_5_NUP98-ADD3_NUP98_chr11_3765738_ENST00000397007_ADD3_chr10_111893083_ENST00000360162_length(transcript)=2640nt_BP=1635nt
GGCCCTCTGCGCGCTGCGCCCGAAGCGGCGGTCGGTGGCAGGGGTGGTAGCGGCGGCGGCGACGGTTTCGTGGGGGCCGCGCGCTGCTCT
GTGAGCGGCGGGTGGCAGCAGGGGACTCCTGACACTTCCCCTTCCCCACCGAACCGCGCTTTCTGAAACAAAGACTCATTTTGAAGATGT
TTAACAAATCATTTGGAACACCCTTTGGGGGTGGCACAGGTGGCTTTGGCACAACTTCAACATTTGGACAGAATACTGGCTTTGGCACTA
CTAGTGGAGGGGCATTTGGAACATCTGCATTTGGTTCTAGCAACAATACTGGAGGCCTCTTTGGAAATTCACAGACTAAACCAGGAGGAT
TGTTTGGAACCAGTTCATTTAGCCAGCCAGCTACCTCCACAAGCACTGGCTTTGGGTTTGGTACGTCAACAGGAACAGCAAATACCTTGT
TTGGAACTGCAAGCACAGGGACCAGTCTCTTCTCATCCCAAAACAATGCCTTTGCACAAAATAAACCAACTGGCTTTGGCAATTTTGGAA
CCAGTACTAGCAGTGGAGGACTCTTTGGAACCACAAATACCACCTCTAATCCTTTTGGCAGCACATCTGGCTCCCTCTTTGGGCCAAGTA
GTTTTACAGCTGCTCCTACTGGGACTACTATTAAATTTAACCCTCCAACTGGTACAGATACTATGGTCAAAGCTGGAGTTAGCACTAACA
TAAGTACCAAGCACCAGTGTATTACTGCTATGAAAGAATATGAAAGCAAGTCACTAGAGGAACTTCGTTTAGAGGATTATCAGGCTAACA
GGAAGGGCCCACAGAACCAGGTGGGAGCAGGTACCACAACTGGCTTGTTTGGGTCTTCTCCAGCCACTTCCAGCGCAACAGGACTCTTCA
GCTCCTCCACCACTAATTCAGGCTTTGCATATGGTCAGAACAAAACTGCCTTTGGAACTAGTACAACTGGATTTGGAACAAATCCAGGTG
GTCTCTTTGGCCAACAGAATCAGCAGACTACCAGCCTCTTCAGCAAACCATTTGGCCAGGCTACAACCACCCAGAACACTGGCTTTTCCT
TTGGTAATACCAGCACCATAGGACAGCCAAGCACCAACACCATGGGATTATTTGGAGTAACCCAAGCCTCACAGCCTGGAGGTCTTTTTG
GGACAGCTACAAACACCAGCACTGGGACAGCATTTGGAACAGGAACAGGTCTCTTTGGGCAGACCAATACTGGATTTGGTGCTGTTGGTT
CGACCCTGTTTGGCAATAACAAGCTTACTACATTTGGAAGCAGCACAACCAGTGCACCTTCATTTGGTACAACCAGTGGCGGGCTCTTTG
GTAACAAACCAACCCTGACTTTAGGAACCAATACAAACACTTCTAATTTTGGTTTTGGCACAAATACCAGTGGGAATAGTATTTTTGGAA
GTAAACCAGCACCTGGGACTCTTGGAACTGGGCTTGGTGCAGGATTTGGAACAGCTCTTGGTGCTGGACAGGCATCTTTGTTTGGGAACA
ACCAACCTAAGATTGGAGGGCCTCTTGGTACAGGAGCCTTTGGGGCCCCTGGATTTAATACTACGACAGCCACTTTGGGCTTTGGAGCCC
CCCAGGCCCCAGTAGAAAACCATGAGCTGTTTTCCAAGAGCTTCATCTCCATGGAAGTGCCTGTCATGGTAGTAAATGGCAAGGATGATA
TGCATGATGTTGAAGATGAGCTTGCTAAGCGAGTGAGTAGGTTAAGCACAAGTACAACCATAGAAAACATCGAGATTACTATTAAGTCTC
CAGAGAAAATCGAAGAAGTCCTGTCACCTGAAGGCTCCCCTTCAAAATCGCCATCCAAGAAAAAGAAGAAATTCCGCACTCCTTCTTTTC
TGAAAAAGAACAAAAAAAAGGAGAAAGTTGAGGCCTAAATAAAGTCTTTTTATAATTATTATTATAACAATGTGACATTGCACATCTAAA
TACCACATTTAAGTTGATCATTAATATGCAATGGTAGATCAGATTGGGGGATGTAGCAAACTGGACTTTAAGAACTGGAAAGAGGTTTTA
CAAAAGAAAAACTTTCAGATTCATCTCTCATTTTATATGTCCAGAAATGGCTTTGAATTTTAAGCAATTACTAGTTTTAATTAGCTCTGC
CCTCATGAAGTATTATTATAATTCACCATAAACAGCTATCTGTCTGAATTACTTCAGGCCTTCTCCATAATATCTGTTAGAAAGAAATTG
CCAGTGAGCAAGTGAGAATTTTTATTTCTCAATACCTGCTTCACTTGATAATCATATTATAATTTTTTATCATGATTATTGACTATATTT
TTGGAGTCCCATTGTTTCAGTGGGCATTAACAGAATGCTTTAAAAACTTCTAAGACAAGAATCTATAGCATTAGTATACACTGGCACATA
ATTTTTTAAAAAGTTTTAAGAAAAGATTCATTTGGAATTTTATTCACAGTATAAAATTTCCTCACCTGAAGTAACTTTGTTTGCCAAAAA
AGTTGTTTTAATAAACTATAATTTTTGAAAACTTCCTTTTTTATTAGTTTAGAAAGCCCCTTATTTTTCAACAAAGGGGATTTTGTACAC

>61107_61107_5_NUP98-ADD3_NUP98_chr11_3765738_ENST00000397007_ADD3_chr10_111893083_ENST00000360162_length(amino acids)=591AA_BP=493
MKQRLILKMFNKSFGTPFGGGTGGFGTTSTFGQNTGFGTTSGGAFGTSAFGSSNNTGGLFGNSQTKPGGLFGTSSFSQPATSTSTGFGFG
TSTGTANTLFGTASTGTSLFSSQNNAFAQNKPTGFGNFGTSTSSGGLFGTTNTTSNPFGSTSGSLFGPSSFTAAPTGTTIKFNPPTGTDT
MVKAGVSTNISTKHQCITAMKEYESKSLEELRLEDYQANRKGPQNQVGAGTTTGLFGSSPATSSATGLFSSSTTNSGFAYGQNKTAFGTS
TTGFGTNPGGLFGQQNQQTTSLFSKPFGQATTTQNTGFSFGNTSTIGQPSTNTMGLFGVTQASQPGGLFGTATNTSTGTAFGTGTGLFGQ
TNTGFGAVGSTLFGNNKLTTFGSSTTSAPSFGTTSGGLFGNKPTLTLGTNTNTSNFGFGTNTSGNSIFGSKPAPGTLGTGLGAGFGTALG
AGQASLFGNNQPKIGGPLGTGAFGAPGFNTTTATLGFGAPQAPVENHELFSKSFISMEVPVMVVNGKDDMHDVEDELAKRVSRLSTSTTI

--------------------------------------------------------------

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Fusion Gene PPI Analysis for NUP98-ADD3


check button Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in

ChiPPI page.


check button Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160)
HgeneHgene's interactorsTgeneTgene's interactors


check button - Retained PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenStill interaction with


check button - Lost PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


check button - Retained PPIs, but lost function due to frame-shift fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


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Related Drugs for NUP98-ADD3


check button Drugs targeting genes involved in this fusion gene.
(DrugBank Version 5.1.8 2021-05-08)
PartnerGeneUniProtAccDrugBank IDDrug nameDrug activityDrug typeDrug status

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Related Diseases for NUP98-ADD3


check button Diseases associated with fusion partners.
(DisGeNet 4.0)
PartnerGeneDisease IDDisease name# pubmedsSource