FusionGDB Logo

Home

Download

Statistics

Examples

Help

Contact
Center for Computational Systems Medicine
leaf

Fusion Gene Summary

leaf

Fusion Gene ORF analysis

leaf

Fusion Genomic Features

leaf

Fusion Protein Features

leaf

Fusion Gene Sequence

leaf

Fusion Gene PPI analysis

leaf

Related Drugs

leaf

Related Diseases

Fusion gene:NXF1-STX5 (FusionGDB2 ID:61207)

Fusion Gene Summary for NXF1-STX5

check button Fusion gene summary
Fusion gene informationFusion gene name: NXF1-STX5
Fusion gene ID: 61207
HgeneTgene
Gene symbol

NXF1

STX5

Gene ID

10482

6811

Gene namenuclear RNA export factor 1syntaxin 5
SynonymsMEX67|TAPSED5|STX5A
Cytomap

11q12.3

11q12.3

Type of geneprotein-codingprotein-coding
Descriptionnuclear RNA export factor 1mRNA export factor TAPtip associating proteintip-associated proteinsyntaxin-5syntaxin 5A
Modification date2020031320200313
UniProtAcc..
Ensembl transtripts involved in fusion geneENST00000531709, ENST00000533048, 
ENST00000294172, ENST00000532297, 
ENST00000439713, ENST00000531131, 
ENST00000294179, ENST00000377897, 
ENST00000394690, ENST00000541317, 
Fusion gene scores* DoF score10 X 13 X 7=9106 X 2 X 7=84
# samples 129
** MAII scorelog2(12/910*10)=-2.92283213947754
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0		log2(9/84*10)=0.0995356735509144
effective Gene in Pan-Cancer Fusion Genes (eGinPCFGs).
DoF>8 and MAII>0
Context

PubMed: NXF1 [Title/Abstract] AND STX5 [Title/Abstract] AND fusion [Title/Abstract]

Most frequent breakpointNXF1(62566011)-STX5(62575100), # samples:2
NXF1(62563932)-STX5(62575100), # samples:2
Anticipated loss of major functional domain due to fusion event.NXF1-STX5 seems lost the major protein functional domain in Hgene partner, which is a essential gene due to the frame-shifted ORF.
NXF1-STX5 seems lost the major protein functional domain in Tgene partner, which is a essential gene due to the frame-shifted ORF.
* DoF score (Degree of Frequency) = # partners X # break points X # cancer types
** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)

check button Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez
PartnerGeneGO IDGO termPubMed ID
HgeneNXF1

GO:0006406

mRNA export from nucleus

19165146|28984244

TgeneSTX5

GO:0042147

retrograde transport, endosome to Golgi

15215310

TgeneSTX5

GO:0090166

Golgi disassembly

16081076

TgeneSTX5

GO:1903358

regulation of Golgi organization

16081076


check buttonFusion gene breakpoints across NXF1 (5'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check buttonFusion gene breakpoints across STX5 (3'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check button Fusion gene information from two resources (ChiTars 5.0 and ChimerDB 4.0)
* All genome coordinats were lifted-over on hg19.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
SourceDiseaseSampleHgeneHchrHbpHstrandTgeneTchrTbpTstrand
ChimerDB4LIHCTCGA-DD-A3A1-01ANXF1chr11

62566011

-STX5chr11

62575100

-
ChimerDB4UCSTCGA-NA-A4R1-01ANXF1chr11

62563931

-STX5chr11

62575099

-
ChimerDB4UCSTCGA-NA-A4R1-01ANXF1chr11

62563932

-STX5chr11

62575100

-
ChimerDB4UCSTCGA-NA-A4R1NXF1chr11

62563759

-STX5chr11

62575100

-
ChimerDB4UCSTCGA-NA-A4R1NXF1chr11

62563932

-STX5chr11

62575100

-


Top

Fusion Gene ORF analysis for NXF1-STX5

check button Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
ORFHenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrand
3UTR-3CDSENST00000531709ENST00000294179NXF1chr11

62566011

-STX5chr11

62575100

-
3UTR-3CDSENST00000531709ENST00000294179NXF1chr11

62563931

-STX5chr11

62575099

-
3UTR-3CDSENST00000531709ENST00000294179NXF1chr11

62563759

-STX5chr11

62575100

-
3UTR-3CDSENST00000531709ENST00000294179NXF1chr11

62563932

-STX5chr11

62575100

-
3UTR-3CDSENST00000531709ENST00000377897NXF1chr11

62566011

-STX5chr11

62575100

-
3UTR-3CDSENST00000531709ENST00000377897NXF1chr11

62563931

-STX5chr11

62575099

-
3UTR-3CDSENST00000531709ENST00000377897NXF1chr11

62563759

-STX5chr11

62575100

-
3UTR-3CDSENST00000531709ENST00000377897NXF1chr11

62563932

-STX5chr11

62575100

-
3UTR-3CDSENST00000531709ENST00000394690NXF1chr11

62566011

-STX5chr11

62575100

-
3UTR-3CDSENST00000531709ENST00000394690NXF1chr11

62563931

-STX5chr11

62575099

-
3UTR-3CDSENST00000531709ENST00000394690NXF1chr11

62563759

-STX5chr11

62575100

-
3UTR-3CDSENST00000531709ENST00000394690NXF1chr11

62563932

-STX5chr11

62575100

-
3UTR-3CDSENST00000531709ENST00000541317NXF1chr11

62566011

-STX5chr11

62575100

-
3UTR-3CDSENST00000531709ENST00000541317NXF1chr11

62563931

-STX5chr11

62575099

-
3UTR-3CDSENST00000531709ENST00000541317NXF1chr11

62563759

-STX5chr11

62575100

-
3UTR-3CDSENST00000531709ENST00000541317NXF1chr11

62563932

-STX5chr11

62575100

-
5UTR-3CDSENST00000533048ENST00000294179NXF1chr11

62563931

-STX5chr11

62575099

-
5UTR-3CDSENST00000533048ENST00000294179NXF1chr11

62563759

-STX5chr11

62575100

-
5UTR-3CDSENST00000533048ENST00000294179NXF1chr11

62563932

-STX5chr11

62575100

-
5UTR-3CDSENST00000533048ENST00000377897NXF1chr11

62563931

-STX5chr11

62575099

-
5UTR-3CDSENST00000533048ENST00000377897NXF1chr11

62563759

-STX5chr11

62575100

-
5UTR-3CDSENST00000533048ENST00000377897NXF1chr11

62563932

-STX5chr11

62575100

-
5UTR-3CDSENST00000533048ENST00000394690NXF1chr11

62563931

-STX5chr11

62575099

-
5UTR-3CDSENST00000533048ENST00000394690NXF1chr11

62563759

-STX5chr11

62575100

-
5UTR-3CDSENST00000533048ENST00000394690NXF1chr11

62563932

-STX5chr11

62575100

-
5UTR-3CDSENST00000533048ENST00000541317NXF1chr11

62563931

-STX5chr11

62575099

-
5UTR-3CDSENST00000533048ENST00000541317NXF1chr11

62563759

-STX5chr11

62575100

-
5UTR-3CDSENST00000533048ENST00000541317NXF1chr11

62563932

-STX5chr11

62575100

-
Frame-shiftENST00000294172ENST00000294179NXF1chr11

62566011

-STX5chr11

62575100

-
Frame-shiftENST00000294172ENST00000294179NXF1chr11

62563931

-STX5chr11

62575099

-
Frame-shiftENST00000294172ENST00000294179NXF1chr11

62563932

-STX5chr11

62575100

-
Frame-shiftENST00000294172ENST00000377897NXF1chr11

62566011

-STX5chr11

62575100

-
Frame-shiftENST00000294172ENST00000377897NXF1chr11

62563759

-STX5chr11

62575100

-
Frame-shiftENST00000294172ENST00000394690NXF1chr11

62566011

-STX5chr11

62575100

-
Frame-shiftENST00000294172ENST00000394690NXF1chr11

62563759

-STX5chr11

62575100

-
Frame-shiftENST00000294172ENST00000541317NXF1chr11

62566011

-STX5chr11

62575100

-
Frame-shiftENST00000294172ENST00000541317NXF1chr11

62563759

-STX5chr11

62575100

-
Frame-shiftENST00000532297ENST00000294179NXF1chr11

62566011

-STX5chr11

62575100

-
Frame-shiftENST00000532297ENST00000294179NXF1chr11

62563759

-STX5chr11

62575100

-
Frame-shiftENST00000532297ENST00000377897NXF1chr11

62563931

-STX5chr11

62575099

-
Frame-shiftENST00000532297ENST00000377897NXF1chr11

62563759

-STX5chr11

62575100

-
Frame-shiftENST00000532297ENST00000377897NXF1chr11

62563932

-STX5chr11

62575100

-
Frame-shiftENST00000532297ENST00000394690NXF1chr11

62563931

-STX5chr11

62575099

-
Frame-shiftENST00000532297ENST00000394690NXF1chr11

62563759

-STX5chr11

62575100

-
Frame-shiftENST00000532297ENST00000394690NXF1chr11

62563932

-STX5chr11

62575100

-
Frame-shiftENST00000532297ENST00000541317NXF1chr11

62563931

-STX5chr11

62575099

-
Frame-shiftENST00000532297ENST00000541317NXF1chr11

62563759

-STX5chr11

62575100

-
Frame-shiftENST00000532297ENST00000541317NXF1chr11

62563932

-STX5chr11

62575100

-
In-frameENST00000294172ENST00000294179NXF1chr11

62563759

-STX5chr11

62575100

-
In-frameENST00000294172ENST00000377897NXF1chr11

62563931

-STX5chr11

62575099

-
In-frameENST00000294172ENST00000377897NXF1chr11

62563932

-STX5chr11

62575100

-
In-frameENST00000294172ENST00000394690NXF1chr11

62563931

-STX5chr11

62575099

-
In-frameENST00000294172ENST00000394690NXF1chr11

62563932

-STX5chr11

62575100

-
In-frameENST00000294172ENST00000541317NXF1chr11

62563931

-STX5chr11

62575099

-
In-frameENST00000294172ENST00000541317NXF1chr11

62563932

-STX5chr11

62575100

-
In-frameENST00000532297ENST00000294179NXF1chr11

62563931

-STX5chr11

62575099

-
In-frameENST00000532297ENST00000294179NXF1chr11

62563932

-STX5chr11

62575100

-
In-frameENST00000532297ENST00000377897NXF1chr11

62566011

-STX5chr11

62575100

-
In-frameENST00000532297ENST00000394690NXF1chr11

62566011

-STX5chr11

62575100

-
In-frameENST00000532297ENST00000541317NXF1chr11

62566011

-STX5chr11

62575100

-
intron-3CDSENST00000439713ENST00000294179NXF1chr11

62566011

-STX5chr11

62575100

-
intron-3CDSENST00000439713ENST00000294179NXF1chr11

62563931

-STX5chr11

62575099

-
intron-3CDSENST00000439713ENST00000294179NXF1chr11

62563759

-STX5chr11

62575100

-
intron-3CDSENST00000439713ENST00000294179NXF1chr11

62563932

-STX5chr11

62575100

-
intron-3CDSENST00000439713ENST00000377897NXF1chr11

62566011

-STX5chr11

62575100

-
intron-3CDSENST00000439713ENST00000377897NXF1chr11

62563931

-STX5chr11

62575099

-
intron-3CDSENST00000439713ENST00000377897NXF1chr11

62563759

-STX5chr11

62575100

-
intron-3CDSENST00000439713ENST00000377897NXF1chr11

62563932

-STX5chr11

62575100

-
intron-3CDSENST00000439713ENST00000394690NXF1chr11

62566011

-STX5chr11

62575100

-
intron-3CDSENST00000439713ENST00000394690NXF1chr11

62563931

-STX5chr11

62575099

-
intron-3CDSENST00000439713ENST00000394690NXF1chr11

62563759

-STX5chr11

62575100

-
intron-3CDSENST00000439713ENST00000394690NXF1chr11

62563932

-STX5chr11

62575100

-
intron-3CDSENST00000439713ENST00000541317NXF1chr11

62566011

-STX5chr11

62575100

-
intron-3CDSENST00000439713ENST00000541317NXF1chr11

62563931

-STX5chr11

62575099

-
intron-3CDSENST00000439713ENST00000541317NXF1chr11

62563759

-STX5chr11

62575100

-
intron-3CDSENST00000439713ENST00000541317NXF1chr11

62563932

-STX5chr11

62575100

-
intron-3CDSENST00000531131ENST00000294179NXF1chr11

62566011

-STX5chr11

62575100

-
intron-3CDSENST00000531131ENST00000294179NXF1chr11

62563931

-STX5chr11

62575099

-
intron-3CDSENST00000531131ENST00000294179NXF1chr11

62563759

-STX5chr11

62575100

-
intron-3CDSENST00000531131ENST00000294179NXF1chr11

62563932

-STX5chr11

62575100

-
intron-3CDSENST00000531131ENST00000377897NXF1chr11

62566011

-STX5chr11

62575100

-
intron-3CDSENST00000531131ENST00000377897NXF1chr11

62563931

-STX5chr11

62575099

-
intron-3CDSENST00000531131ENST00000377897NXF1chr11

62563759

-STX5chr11

62575100

-
intron-3CDSENST00000531131ENST00000377897NXF1chr11

62563932

-STX5chr11

62575100

-
intron-3CDSENST00000531131ENST00000394690NXF1chr11

62566011

-STX5chr11

62575100

-
intron-3CDSENST00000531131ENST00000394690NXF1chr11

62563931

-STX5chr11

62575099

-
intron-3CDSENST00000531131ENST00000394690NXF1chr11

62563759

-STX5chr11

62575100

-
intron-3CDSENST00000531131ENST00000394690NXF1chr11

62563932

-STX5chr11

62575100

-
intron-3CDSENST00000531131ENST00000541317NXF1chr11

62566011

-STX5chr11

62575100

-
intron-3CDSENST00000531131ENST00000541317NXF1chr11

62563931

-STX5chr11

62575099

-
intron-3CDSENST00000531131ENST00000541317NXF1chr11

62563759

-STX5chr11

62575100

-
intron-3CDSENST00000531131ENST00000541317NXF1chr11

62563932

-STX5chr11

62575100

-
intron-3CDSENST00000533048ENST00000294179NXF1chr11

62566011

-STX5chr11

62575100

-
intron-3CDSENST00000533048ENST00000377897NXF1chr11

62566011

-STX5chr11

62575100

-
intron-3CDSENST00000533048ENST00000394690NXF1chr11

62566011

-STX5chr11

62575100

-
intron-3CDSENST00000533048ENST00000541317NXF1chr11

62566011

-STX5chr11

62575100

-

check buttonORFfinder result based on the fusion transcript sequence of in-frame fusion genes.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandSeq length
(transcript)		BP loci
(transcript)		Predicted start
(transcript)		Predicted stop
(transcript)		Seq length
(amino acids)

check buttonDeepORF prediction of the coding potential based on the fusion transcript sequence of in-frame fusion genes. DeepORF is a coding potential classifier based on convolutional neural network by comparing the real Ribo-seq data. If the no-coding score < 0.5 and coding score > 0.5, then the in-frame fusion transcript is predicted as being likely translated.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandNo-coding scoreCoding score

Top

Fusion Genomic Features for NXF1-STX5


check buttonFusionAI prediction of the potential fusion gene breakpoint based on the pre-mature RNA sequence context (+/- 5kb of individual partner genes, total 20kb length sequence). FusionAI is a fusion gene breakpoint classifier based on convolutional neural network by comparing the fusion positive and negative sequence context of ~ 20K fusion gene data. From here, we can have the relative potentency of the 20K genomic sequence how individual sequnce will be likely used as the gene fusion breakpoints.
HgeneHchrHbpHstrandTgeneTchrTbpTstrand1-pp (fusion gene breakpoint)

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions. We integrated a total of 44 different types of human genomic feature loci information across five big categories including virus integration sites, repeats, structural variants, chromatin states, and gene expression regulation. More details are in help page.
genomic feature

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions that are ovelapped with the top 1% feature importance score regions. More details are in help page.

Top

Fusion Protein Features for NXF1-STX5


check button Four levels of functional features of fusion genes
Go to FGviewer search page for the most frequent breakpoint (https://ccsmweb.uth.edu/FGviewer/chr11:62566011/chr11:62575100)
- FGviewer provides the online visualization of the retention search of the protein functional features across DNA, RNA, protein, and pathological levels.
- How to search
1. Put your fusion gene symbol.
2. Press the tab key until there will be shown the breakpoint information filled.
4. Go down and press 'Search' tab twice.
4. Go down to have the hyperlink of the search result.
5. Click the hyperlink.
6. See the FGviewer result for your fusion gene.
FGviewer

check buttonMain function of each fusion partner protein. (from UniProt)
HgeneTgene
..
FUNCTION: Transcriptional activator which is required for calcium-dependent dendritic growth and branching in cortical neurons. Recruits CREB-binding protein (CREBBP) to nuclear bodies. Component of the CREST-BRG1 complex, a multiprotein complex that regulates promoter activation by orchestrating a calcium-dependent release of a repressor complex and a recruitment of an activator complex. In resting neurons, transcription of the c-FOS promoter is inhibited by BRG1-dependent recruitment of a phospho-RB1-HDAC1 repressor complex. Upon calcium influx, RB1 is dephosphorylated by calcineurin, which leads to release of the repressor complex. At the same time, there is increased recruitment of CREBBP to the promoter by a CREST-dependent mechanism, which leads to transcriptional activation. The CREST-BRG1 complex also binds to the NR2B promoter, and activity-dependent induction of NR2B expression involves a release of HDAC1 and recruitment of CREBBP (By similarity). {ECO:0000250}.FUNCTION: Transcriptional activator which is required for calcium-dependent dendritic growth and branching in cortical neurons. Recruits CREB-binding protein (CREBBP) to nuclear bodies. Component of the CREST-BRG1 complex, a multiprotein complex that regulates promoter activation by orchestrating a calcium-dependent release of a repressor complex and a recruitment of an activator complex. In resting neurons, transcription of the c-FOS promoter is inhibited by BRG1-dependent recruitment of a phospho-RB1-HDAC1 repressor complex. Upon calcium influx, RB1 is dephosphorylated by calcineurin, which leads to release of the repressor complex. At the same time, there is increased recruitment of CREBBP to the promoter by a CREST-dependent mechanism, which leads to transcriptional activation. The CREST-BRG1 complex also binds to the NR2B promoter, and activity-dependent induction of NR2B expression involves a release of HDAC1 and recruitment of CREBBP (By similarity). {ECO:0000250}.

check buttonRetention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at

download page


* Minus value of BPloci means that the break pointn is located before the CDS.
- In-frame and retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneNXF1chr11:62563759chr11:62575100ENST00000531709-1420551_5611048380.6666666666667Compositional biasNote=Pro-rich
HgeneNXF1chr11:62563931chr11:62575099ENST00000531709-1320551_5611029380.6666666666667Compositional biasNote=Pro-rich
HgeneNXF1chr11:62563932chr11:62575100ENST00000531709-1320551_5611029380.6666666666667Compositional biasNote=Pro-rich
HgeneNXF1chr11:62566011chr11:62575100ENST00000531709-1020551_561951380.6666666666667Compositional biasNote=Pro-rich
HgeneNXF1chr11:62563759chr11:62575100ENST00000294172-1521119_198448620.0DomainNote=RRM
HgeneNXF1chr11:62563759chr11:62575100ENST00000531709-1420119_1981048380.6666666666667DomainNote=RRM
HgeneNXF1chr11:62563759chr11:62575100ENST00000531709-1420386_5361048380.6666666666667DomainNTF2
HgeneNXF1chr11:62563759chr11:62575100ENST00000531709-1420565_6191048380.6666666666667DomainTAP-C
HgeneNXF1chr11:62563759chr11:62575100ENST00000532297-1622119_198448620.0DomainNote=RRM
HgeneNXF1chr11:62563931chr11:62575099ENST00000294172-1421119_198428620.0DomainNote=RRM
HgeneNXF1chr11:62563931chr11:62575099ENST00000531709-1320119_1981029380.6666666666667DomainNote=RRM
HgeneNXF1chr11:62563931chr11:62575099ENST00000531709-1320386_5361029380.6666666666667DomainNTF2
HgeneNXF1chr11:62563931chr11:62575099ENST00000531709-1320565_6191029380.6666666666667DomainTAP-C
HgeneNXF1chr11:62563931chr11:62575099ENST00000532297-1522119_198428620.0DomainNote=RRM
HgeneNXF1chr11:62563932chr11:62575100ENST00000294172-1421119_198428620.0DomainNote=RRM
HgeneNXF1chr11:62563932chr11:62575100ENST00000531709-1320119_1981029380.6666666666667DomainNote=RRM
HgeneNXF1chr11:62563932chr11:62575100ENST00000531709-1320386_5361029380.6666666666667DomainNTF2
HgeneNXF1chr11:62563932chr11:62575100ENST00000531709-1320565_6191029380.6666666666667DomainTAP-C
HgeneNXF1chr11:62563932chr11:62575100ENST00000532297-1522119_198428620.0DomainNote=RRM
HgeneNXF1chr11:62566011chr11:62575100ENST00000294172-1121119_198351620.0DomainNote=RRM
HgeneNXF1chr11:62566011chr11:62575100ENST00000531709-1020119_198951380.6666666666667DomainNote=RRM
HgeneNXF1chr11:62566011chr11:62575100ENST00000531709-1020386_536951380.6666666666667DomainNTF2
HgeneNXF1chr11:62566011chr11:62575100ENST00000531709-1020565_619951380.6666666666667DomainTAP-C
HgeneNXF1chr11:62566011chr11:62575100ENST00000532297-1222119_198351620.0DomainNote=RRM
HgeneNXF1chr11:62563759chr11:62575100ENST00000294172-152167_100448620.0MotifNote=Nuclear localization signal
HgeneNXF1chr11:62563759chr11:62575100ENST00000294172-152183_110448620.0MotifNote=Nuclear export signal
HgeneNXF1chr11:62563759chr11:62575100ENST00000531709-142067_1001048380.6666666666667MotifNote=Nuclear localization signal
HgeneNXF1chr11:62563759chr11:62575100ENST00000531709-142083_1101048380.6666666666667MotifNote=Nuclear export signal
HgeneNXF1chr11:62563759chr11:62575100ENST00000532297-162267_100448620.0MotifNote=Nuclear localization signal
HgeneNXF1chr11:62563759chr11:62575100ENST00000532297-162283_110448620.0MotifNote=Nuclear export signal
HgeneNXF1chr11:62563931chr11:62575099ENST00000294172-142167_100428620.0MotifNote=Nuclear localization signal
HgeneNXF1chr11:62563931chr11:62575099ENST00000294172-142183_110428620.0MotifNote=Nuclear export signal
HgeneNXF1chr11:62563931chr11:62575099ENST00000531709-132067_1001029380.6666666666667MotifNote=Nuclear localization signal
HgeneNXF1chr11:62563931chr11:62575099ENST00000531709-132083_1101029380.6666666666667MotifNote=Nuclear export signal
HgeneNXF1chr11:62563931chr11:62575099ENST00000532297-152267_100428620.0MotifNote=Nuclear localization signal
HgeneNXF1chr11:62563931chr11:62575099ENST00000532297-152283_110428620.0MotifNote=Nuclear export signal
HgeneNXF1chr11:62563932chr11:62575100ENST00000294172-142167_100428620.0MotifNote=Nuclear localization signal
HgeneNXF1chr11:62563932chr11:62575100ENST00000294172-142183_110428620.0MotifNote=Nuclear export signal
HgeneNXF1chr11:62563932chr11:62575100ENST00000531709-132067_1001029380.6666666666667MotifNote=Nuclear localization signal
HgeneNXF1chr11:62563932chr11:62575100ENST00000531709-132083_1101029380.6666666666667MotifNote=Nuclear export signal
HgeneNXF1chr11:62563932chr11:62575100ENST00000532297-152267_100428620.0MotifNote=Nuclear localization signal
HgeneNXF1chr11:62563932chr11:62575100ENST00000532297-152283_110428620.0MotifNote=Nuclear export signal
HgeneNXF1chr11:62566011chr11:62575100ENST00000294172-112167_100351620.0MotifNote=Nuclear localization signal
HgeneNXF1chr11:62566011chr11:62575100ENST00000294172-112183_110351620.0MotifNote=Nuclear export signal
HgeneNXF1chr11:62566011chr11:62575100ENST00000531709-102067_100951380.6666666666667MotifNote=Nuclear localization signal
HgeneNXF1chr11:62566011chr11:62575100ENST00000531709-102083_110951380.6666666666667MotifNote=Nuclear export signal
HgeneNXF1chr11:62566011chr11:62575100ENST00000532297-122267_100351620.0MotifNote=Nuclear localization signal
HgeneNXF1chr11:62566011chr11:62575100ENST00000532297-122283_110351620.0MotifNote=Nuclear export signal
HgeneNXF1chr11:62563759chr11:62575100ENST00000294172-15212_118448620.0RegionNote=RNA-binding (RBD)
HgeneNXF1chr11:62563759chr11:62575100ENST00000294172-15212_60448620.0RegionNote=Minor non-specific RNA-binding
HgeneNXF1chr11:62563759chr11:62575100ENST00000294172-152161_118448620.0RegionNote=Major non-specific RNA-binding
HgeneNXF1chr11:62563759chr11:62575100ENST00000531709-14202_1181048380.6666666666667RegionNote=RNA-binding (RBD)
HgeneNXF1chr11:62563759chr11:62575100ENST00000531709-14202_601048380.6666666666667RegionNote=Minor non-specific RNA-binding
HgeneNXF1chr11:62563759chr11:62575100ENST00000531709-142061_1181048380.6666666666667RegionNote=Major non-specific RNA-binding
HgeneNXF1chr11:62563759chr11:62575100ENST00000532297-16222_118448620.0RegionNote=RNA-binding (RBD)
HgeneNXF1chr11:62563759chr11:62575100ENST00000532297-16222_60448620.0RegionNote=Minor non-specific RNA-binding
HgeneNXF1chr11:62563759chr11:62575100ENST00000532297-162261_118448620.0RegionNote=Major non-specific RNA-binding
HgeneNXF1chr11:62563931chr11:62575099ENST00000294172-14212_118428620.0RegionNote=RNA-binding (RBD)
HgeneNXF1chr11:62563931chr11:62575099ENST00000294172-14212_60428620.0RegionNote=Minor non-specific RNA-binding
HgeneNXF1chr11:62563931chr11:62575099ENST00000294172-142161_118428620.0RegionNote=Major non-specific RNA-binding
HgeneNXF1chr11:62563931chr11:62575099ENST00000531709-13202_1181029380.6666666666667RegionNote=RNA-binding (RBD)
HgeneNXF1chr11:62563931chr11:62575099ENST00000531709-13202_601029380.6666666666667RegionNote=Minor non-specific RNA-binding
HgeneNXF1chr11:62563931chr11:62575099ENST00000531709-132061_1181029380.6666666666667RegionNote=Major non-specific RNA-binding
HgeneNXF1chr11:62563931chr11:62575099ENST00000532297-15222_118428620.0RegionNote=RNA-binding (RBD)
HgeneNXF1chr11:62563931chr11:62575099ENST00000532297-15222_60428620.0RegionNote=Minor non-specific RNA-binding
HgeneNXF1chr11:62563931chr11:62575099ENST00000532297-152261_118428620.0RegionNote=Major non-specific RNA-binding
HgeneNXF1chr11:62563932chr11:62575100ENST00000294172-14212_118428620.0RegionNote=RNA-binding (RBD)
HgeneNXF1chr11:62563932chr11:62575100ENST00000294172-14212_60428620.0RegionNote=Minor non-specific RNA-binding
HgeneNXF1chr11:62563932chr11:62575100ENST00000294172-142161_118428620.0RegionNote=Major non-specific RNA-binding
HgeneNXF1chr11:62563932chr11:62575100ENST00000531709-13202_1181029380.6666666666667RegionNote=RNA-binding (RBD)
HgeneNXF1chr11:62563932chr11:62575100ENST00000531709-13202_601029380.6666666666667RegionNote=Minor non-specific RNA-binding
HgeneNXF1chr11:62563932chr11:62575100ENST00000531709-132061_1181029380.6666666666667RegionNote=Major non-specific RNA-binding
HgeneNXF1chr11:62563932chr11:62575100ENST00000532297-15222_118428620.0RegionNote=RNA-binding (RBD)
HgeneNXF1chr11:62563932chr11:62575100ENST00000532297-15222_60428620.0RegionNote=Minor non-specific RNA-binding
HgeneNXF1chr11:62563932chr11:62575100ENST00000532297-152261_118428620.0RegionNote=Major non-specific RNA-binding
HgeneNXF1chr11:62566011chr11:62575100ENST00000294172-11212_118351620.0RegionNote=RNA-binding (RBD)
HgeneNXF1chr11:62566011chr11:62575100ENST00000294172-11212_60351620.0RegionNote=Minor non-specific RNA-binding
HgeneNXF1chr11:62566011chr11:62575100ENST00000294172-112161_118351620.0RegionNote=Major non-specific RNA-binding
HgeneNXF1chr11:62566011chr11:62575100ENST00000531709-10202_118951380.6666666666667RegionNote=RNA-binding (RBD)
HgeneNXF1chr11:62566011chr11:62575100ENST00000531709-10202_60951380.6666666666667RegionNote=Minor non-specific RNA-binding
HgeneNXF1chr11:62566011chr11:62575100ENST00000531709-102061_118951380.6666666666667RegionNote=Major non-specific RNA-binding
HgeneNXF1chr11:62566011chr11:62575100ENST00000532297-12222_118351620.0RegionNote=RNA-binding (RBD)
HgeneNXF1chr11:62566011chr11:62575100ENST00000532297-12222_60351620.0RegionNote=Minor non-specific RNA-binding
HgeneNXF1chr11:62566011chr11:62575100ENST00000532297-122261_118351620.0RegionNote=Major non-specific RNA-binding
HgeneNXF1chr11:62563759chr11:62575100ENST00000294172-1521266_291448620.0RepeatNote=LRR 1
HgeneNXF1chr11:62563759chr11:62575100ENST00000294172-1521292_315448620.0RepeatNote=LRR 2
HgeneNXF1chr11:62563759chr11:62575100ENST00000294172-1521316_343448620.0RepeatNote=LRR 3
HgeneNXF1chr11:62563759chr11:62575100ENST00000294172-1521344_371448620.0RepeatNote=LRR 4
HgeneNXF1chr11:62563759chr11:62575100ENST00000531709-1420266_2911048380.6666666666667RepeatNote=LRR 1
HgeneNXF1chr11:62563759chr11:62575100ENST00000531709-1420292_3151048380.6666666666667RepeatNote=LRR 2
HgeneNXF1chr11:62563759chr11:62575100ENST00000531709-1420316_3431048380.6666666666667RepeatNote=LRR 3
HgeneNXF1chr11:62563759chr11:62575100ENST00000531709-1420344_3711048380.6666666666667RepeatNote=LRR 4
HgeneNXF1chr11:62563759chr11:62575100ENST00000532297-1622266_291448620.0RepeatNote=LRR 1
HgeneNXF1chr11:62563759chr11:62575100ENST00000532297-1622292_315448620.0RepeatNote=LRR 2
HgeneNXF1chr11:62563759chr11:62575100ENST00000532297-1622316_343448620.0RepeatNote=LRR 3
HgeneNXF1chr11:62563759chr11:62575100ENST00000532297-1622344_371448620.0RepeatNote=LRR 4
HgeneNXF1chr11:62563931chr11:62575099ENST00000294172-1421266_291428620.0RepeatNote=LRR 1
HgeneNXF1chr11:62563931chr11:62575099ENST00000294172-1421292_315428620.0RepeatNote=LRR 2
HgeneNXF1chr11:62563931chr11:62575099ENST00000294172-1421316_343428620.0RepeatNote=LRR 3
HgeneNXF1chr11:62563931chr11:62575099ENST00000294172-1421344_371428620.0RepeatNote=LRR 4
HgeneNXF1chr11:62563931chr11:62575099ENST00000531709-1320266_2911029380.6666666666667RepeatNote=LRR 1
HgeneNXF1chr11:62563931chr11:62575099ENST00000531709-1320292_3151029380.6666666666667RepeatNote=LRR 2
HgeneNXF1chr11:62563931chr11:62575099ENST00000531709-1320316_3431029380.6666666666667RepeatNote=LRR 3
HgeneNXF1chr11:62563931chr11:62575099ENST00000531709-1320344_3711029380.6666666666667RepeatNote=LRR 4
HgeneNXF1chr11:62563931chr11:62575099ENST00000532297-1522266_291428620.0RepeatNote=LRR 1
HgeneNXF1chr11:62563931chr11:62575099ENST00000532297-1522292_315428620.0RepeatNote=LRR 2
HgeneNXF1chr11:62563931chr11:62575099ENST00000532297-1522316_343428620.0RepeatNote=LRR 3
HgeneNXF1chr11:62563931chr11:62575099ENST00000532297-1522344_371428620.0RepeatNote=LRR 4
HgeneNXF1chr11:62563932chr11:62575100ENST00000294172-1421266_291428620.0RepeatNote=LRR 1
HgeneNXF1chr11:62563932chr11:62575100ENST00000294172-1421292_315428620.0RepeatNote=LRR 2
HgeneNXF1chr11:62563932chr11:62575100ENST00000294172-1421316_343428620.0RepeatNote=LRR 3
HgeneNXF1chr11:62563932chr11:62575100ENST00000294172-1421344_371428620.0RepeatNote=LRR 4
HgeneNXF1chr11:62563932chr11:62575100ENST00000531709-1320266_2911029380.6666666666667RepeatNote=LRR 1
HgeneNXF1chr11:62563932chr11:62575100ENST00000531709-1320292_3151029380.6666666666667RepeatNote=LRR 2
HgeneNXF1chr11:62563932chr11:62575100ENST00000531709-1320316_3431029380.6666666666667RepeatNote=LRR 3
HgeneNXF1chr11:62563932chr11:62575100ENST00000531709-1320344_3711029380.6666666666667RepeatNote=LRR 4
HgeneNXF1chr11:62563932chr11:62575100ENST00000532297-1522266_291428620.0RepeatNote=LRR 1
HgeneNXF1chr11:62563932chr11:62575100ENST00000532297-1522292_315428620.0RepeatNote=LRR 2
HgeneNXF1chr11:62563932chr11:62575100ENST00000532297-1522316_343428620.0RepeatNote=LRR 3
HgeneNXF1chr11:62563932chr11:62575100ENST00000532297-1522344_371428620.0RepeatNote=LRR 4
HgeneNXF1chr11:62566011chr11:62575100ENST00000294172-1121266_291351620.0RepeatNote=LRR 1
HgeneNXF1chr11:62566011chr11:62575100ENST00000294172-1121292_315351620.0RepeatNote=LRR 2
HgeneNXF1chr11:62566011chr11:62575100ENST00000294172-1121316_343351620.0RepeatNote=LRR 3
HgeneNXF1chr11:62566011chr11:62575100ENST00000531709-1020266_291951380.6666666666667RepeatNote=LRR 1
HgeneNXF1chr11:62566011chr11:62575100ENST00000531709-1020292_315951380.6666666666667RepeatNote=LRR 2
HgeneNXF1chr11:62566011chr11:62575100ENST00000531709-1020316_343951380.6666666666667RepeatNote=LRR 3
HgeneNXF1chr11:62566011chr11:62575100ENST00000531709-1020344_371951380.6666666666667RepeatNote=LRR 4
HgeneNXF1chr11:62566011chr11:62575100ENST00000532297-1222266_291351620.0RepeatNote=LRR 1
HgeneNXF1chr11:62566011chr11:62575100ENST00000532297-1222292_315351620.0RepeatNote=LRR 2
HgeneNXF1chr11:62566011chr11:62575100ENST00000532297-1222316_343351620.0RepeatNote=LRR 3
TgeneSTX5chr11:62563759chr11:62575100ENST00000394690911287_318248302.0Coiled coilOntology_term=ECO:0000255
TgeneSTX5chr11:62563931chr11:62575099ENST00000394690911287_318248302.0Coiled coilOntology_term=ECO:0000255
TgeneSTX5chr11:62563932chr11:62575100ENST00000394690911287_318248302.0Coiled coilOntology_term=ECO:0000255
TgeneSTX5chr11:62566011chr11:62575100ENST00000394690911287_318248302.0Coiled coilOntology_term=ECO:0000255
TgeneSTX5chr11:62563759chr11:62575100ENST00000394690911263_325248302.0Domaint-SNARE coiled-coil homology
TgeneSTX5chr11:62563931chr11:62575099ENST00000394690911263_325248302.0Domaint-SNARE coiled-coil homology
TgeneSTX5chr11:62563932chr11:62575100ENST00000394690911263_325248302.0Domaint-SNARE coiled-coil homology
TgeneSTX5chr11:62566011chr11:62575100ENST00000394690911263_325248302.0Domaint-SNARE coiled-coil homology
TgeneSTX5chr11:62563759chr11:62575100ENST00000294179911355_355302356.0Topological domainVesicular
TgeneSTX5chr11:62563759chr11:62575100ENST00000394690911355_355248302.0Topological domainVesicular
TgeneSTX5chr11:62563931chr11:62575099ENST00000294179911355_355302356.0Topological domainVesicular
TgeneSTX5chr11:62563931chr11:62575099ENST00000394690911355_355248302.0Topological domainVesicular
TgeneSTX5chr11:62563932chr11:62575100ENST00000294179911355_355302356.0Topological domainVesicular
TgeneSTX5chr11:62563932chr11:62575100ENST00000394690911355_355248302.0Topological domainVesicular
TgeneSTX5chr11:62566011chr11:62575100ENST00000294179911355_355302356.0Topological domainVesicular
TgeneSTX5chr11:62566011chr11:62575100ENST00000394690911355_355248302.0Topological domainVesicular
TgeneSTX5chr11:62563759chr11:62575100ENST00000294179911334_354302356.0TransmembraneHelical%3B Anchor for type IV membrane protein
TgeneSTX5chr11:62563759chr11:62575100ENST00000394690911334_354248302.0TransmembraneHelical%3B Anchor for type IV membrane protein
TgeneSTX5chr11:62563931chr11:62575099ENST00000294179911334_354302356.0TransmembraneHelical%3B Anchor for type IV membrane protein
TgeneSTX5chr11:62563931chr11:62575099ENST00000394690911334_354248302.0TransmembraneHelical%3B Anchor for type IV membrane protein
TgeneSTX5chr11:62563932chr11:62575100ENST00000294179911334_354302356.0TransmembraneHelical%3B Anchor for type IV membrane protein
TgeneSTX5chr11:62563932chr11:62575100ENST00000394690911334_354248302.0TransmembraneHelical%3B Anchor for type IV membrane protein
TgeneSTX5chr11:62566011chr11:62575100ENST00000294179911334_354302356.0TransmembraneHelical%3B Anchor for type IV membrane protein
TgeneSTX5chr11:62566011chr11:62575100ENST00000394690911334_354248302.0TransmembraneHelical%3B Anchor for type IV membrane protein

- In-frame and not-retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneNXF1chr11:62563759chr11:62575100ENST00000294172-1521551_561448620.0Compositional biasNote=Pro-rich
HgeneNXF1chr11:62563759chr11:62575100ENST00000439713-110551_5610357.0Compositional biasNote=Pro-rich
HgeneNXF1chr11:62563759chr11:62575100ENST00000532297-1622551_561448620.0Compositional biasNote=Pro-rich
HgeneNXF1chr11:62563931chr11:62575099ENST00000294172-1421551_561428620.0Compositional biasNote=Pro-rich
HgeneNXF1chr11:62563931chr11:62575099ENST00000439713-110551_5610357.0Compositional biasNote=Pro-rich
HgeneNXF1chr11:62563931chr11:62575099ENST00000532297-1522551_561428620.0Compositional biasNote=Pro-rich
HgeneNXF1chr11:62563932chr11:62575100ENST00000294172-1421551_561428620.0Compositional biasNote=Pro-rich
HgeneNXF1chr11:62563932chr11:62575100ENST00000439713-110551_5610357.0Compositional biasNote=Pro-rich
HgeneNXF1chr11:62563932chr11:62575100ENST00000532297-1522551_561428620.0Compositional biasNote=Pro-rich
HgeneNXF1chr11:62566011chr11:62575100ENST00000294172-1121551_561351620.0Compositional biasNote=Pro-rich
HgeneNXF1chr11:62566011chr11:62575100ENST00000439713-110551_5610357.0Compositional biasNote=Pro-rich
HgeneNXF1chr11:62566011chr11:62575100ENST00000532297-1222551_561351620.0Compositional biasNote=Pro-rich
HgeneNXF1chr11:62563759chr11:62575100ENST00000294172-1521386_536448620.0DomainNTF2
HgeneNXF1chr11:62563759chr11:62575100ENST00000294172-1521565_619448620.0DomainTAP-C
HgeneNXF1chr11:62563759chr11:62575100ENST00000439713-110119_1980357.0DomainNote=RRM
HgeneNXF1chr11:62563759chr11:62575100ENST00000439713-110386_5360357.0DomainNTF2
HgeneNXF1chr11:62563759chr11:62575100ENST00000439713-110565_6190357.0DomainTAP-C
HgeneNXF1chr11:62563759chr11:62575100ENST00000532297-1622386_536448620.0DomainNTF2
HgeneNXF1chr11:62563759chr11:62575100ENST00000532297-1622565_619448620.0DomainTAP-C
HgeneNXF1chr11:62563931chr11:62575099ENST00000294172-1421386_536428620.0DomainNTF2
HgeneNXF1chr11:62563931chr11:62575099ENST00000294172-1421565_619428620.0DomainTAP-C
HgeneNXF1chr11:62563931chr11:62575099ENST00000439713-110119_1980357.0DomainNote=RRM
HgeneNXF1chr11:62563931chr11:62575099ENST00000439713-110386_5360357.0DomainNTF2
HgeneNXF1chr11:62563931chr11:62575099ENST00000439713-110565_6190357.0DomainTAP-C
HgeneNXF1chr11:62563931chr11:62575099ENST00000532297-1522386_536428620.0DomainNTF2
HgeneNXF1chr11:62563931chr11:62575099ENST00000532297-1522565_619428620.0DomainTAP-C
HgeneNXF1chr11:62563932chr11:62575100ENST00000294172-1421386_536428620.0DomainNTF2
HgeneNXF1chr11:62563932chr11:62575100ENST00000294172-1421565_619428620.0DomainTAP-C
HgeneNXF1chr11:62563932chr11:62575100ENST00000439713-110119_1980357.0DomainNote=RRM
HgeneNXF1chr11:62563932chr11:62575100ENST00000439713-110386_5360357.0DomainNTF2
HgeneNXF1chr11:62563932chr11:62575100ENST00000439713-110565_6190357.0DomainTAP-C
HgeneNXF1chr11:62563932chr11:62575100ENST00000532297-1522386_536428620.0DomainNTF2
HgeneNXF1chr11:62563932chr11:62575100ENST00000532297-1522565_619428620.0DomainTAP-C
HgeneNXF1chr11:62566011chr11:62575100ENST00000294172-1121386_536351620.0DomainNTF2
HgeneNXF1chr11:62566011chr11:62575100ENST00000294172-1121565_619351620.0DomainTAP-C
HgeneNXF1chr11:62566011chr11:62575100ENST00000439713-110119_1980357.0DomainNote=RRM
HgeneNXF1chr11:62566011chr11:62575100ENST00000439713-110386_5360357.0DomainNTF2
HgeneNXF1chr11:62566011chr11:62575100ENST00000439713-110565_6190357.0DomainTAP-C
HgeneNXF1chr11:62566011chr11:62575100ENST00000532297-1222386_536351620.0DomainNTF2
HgeneNXF1chr11:62566011chr11:62575100ENST00000532297-1222565_619351620.0DomainTAP-C
HgeneNXF1chr11:62563759chr11:62575100ENST00000439713-11067_1000357.0MotifNote=Nuclear localization signal
HgeneNXF1chr11:62563759chr11:62575100ENST00000439713-11083_1100357.0MotifNote=Nuclear export signal
HgeneNXF1chr11:62563931chr11:62575099ENST00000439713-11067_1000357.0MotifNote=Nuclear localization signal
HgeneNXF1chr11:62563931chr11:62575099ENST00000439713-11083_1100357.0MotifNote=Nuclear export signal
HgeneNXF1chr11:62563932chr11:62575100ENST00000439713-11067_1000357.0MotifNote=Nuclear localization signal
HgeneNXF1chr11:62563932chr11:62575100ENST00000439713-11083_1100357.0MotifNote=Nuclear export signal
HgeneNXF1chr11:62566011chr11:62575100ENST00000439713-11067_1000357.0MotifNote=Nuclear localization signal
HgeneNXF1chr11:62566011chr11:62575100ENST00000439713-11083_1100357.0MotifNote=Nuclear export signal
HgeneNXF1chr11:62563759chr11:62575100ENST00000439713-1102_1180357.0RegionNote=RNA-binding (RBD)
HgeneNXF1chr11:62563759chr11:62575100ENST00000439713-1102_600357.0RegionNote=Minor non-specific RNA-binding
HgeneNXF1chr11:62563759chr11:62575100ENST00000439713-11061_1180357.0RegionNote=Major non-specific RNA-binding
HgeneNXF1chr11:62563931chr11:62575099ENST00000439713-1102_1180357.0RegionNote=RNA-binding (RBD)
HgeneNXF1chr11:62563931chr11:62575099ENST00000439713-1102_600357.0RegionNote=Minor non-specific RNA-binding
HgeneNXF1chr11:62563931chr11:62575099ENST00000439713-11061_1180357.0RegionNote=Major non-specific RNA-binding
HgeneNXF1chr11:62563932chr11:62575100ENST00000439713-1102_1180357.0RegionNote=RNA-binding (RBD)
HgeneNXF1chr11:62563932chr11:62575100ENST00000439713-1102_600357.0RegionNote=Minor non-specific RNA-binding
HgeneNXF1chr11:62563932chr11:62575100ENST00000439713-11061_1180357.0RegionNote=Major non-specific RNA-binding
HgeneNXF1chr11:62566011chr11:62575100ENST00000439713-1102_1180357.0RegionNote=RNA-binding (RBD)
HgeneNXF1chr11:62566011chr11:62575100ENST00000439713-1102_600357.0RegionNote=Minor non-specific RNA-binding
HgeneNXF1chr11:62566011chr11:62575100ENST00000439713-11061_1180357.0RegionNote=Major non-specific RNA-binding
HgeneNXF1chr11:62563759chr11:62575100ENST00000439713-110266_2910357.0RepeatNote=LRR 1
HgeneNXF1chr11:62563759chr11:62575100ENST00000439713-110292_3150357.0RepeatNote=LRR 2
HgeneNXF1chr11:62563759chr11:62575100ENST00000439713-110316_3430357.0RepeatNote=LRR 3
HgeneNXF1chr11:62563759chr11:62575100ENST00000439713-110344_3710357.0RepeatNote=LRR 4
HgeneNXF1chr11:62563931chr11:62575099ENST00000439713-110266_2910357.0RepeatNote=LRR 1
HgeneNXF1chr11:62563931chr11:62575099ENST00000439713-110292_3150357.0RepeatNote=LRR 2
HgeneNXF1chr11:62563931chr11:62575099ENST00000439713-110316_3430357.0RepeatNote=LRR 3
HgeneNXF1chr11:62563931chr11:62575099ENST00000439713-110344_3710357.0RepeatNote=LRR 4
HgeneNXF1chr11:62563932chr11:62575100ENST00000439713-110266_2910357.0RepeatNote=LRR 1
HgeneNXF1chr11:62563932chr11:62575100ENST00000439713-110292_3150357.0RepeatNote=LRR 2
HgeneNXF1chr11:62563932chr11:62575100ENST00000439713-110316_3430357.0RepeatNote=LRR 3
HgeneNXF1chr11:62563932chr11:62575100ENST00000439713-110344_3710357.0RepeatNote=LRR 4
HgeneNXF1chr11:62566011chr11:62575100ENST00000294172-1121344_371351620.0RepeatNote=LRR 4
HgeneNXF1chr11:62566011chr11:62575100ENST00000439713-110266_2910357.0RepeatNote=LRR 1
HgeneNXF1chr11:62566011chr11:62575100ENST00000439713-110292_3150357.0RepeatNote=LRR 2
HgeneNXF1chr11:62566011chr11:62575100ENST00000439713-110316_3430357.0RepeatNote=LRR 3
HgeneNXF1chr11:62566011chr11:62575100ENST00000439713-110344_3710357.0RepeatNote=LRR 4
HgeneNXF1chr11:62566011chr11:62575100ENST00000532297-1222344_371351620.0RepeatNote=LRR 4
TgeneSTX5chr11:62563759chr11:62575100ENST00000294179911287_318302356.0Coiled coilOntology_term=ECO:0000255
TgeneSTX5chr11:62563931chr11:62575099ENST00000294179911287_318302356.0Coiled coilOntology_term=ECO:0000255
TgeneSTX5chr11:62563932chr11:62575100ENST00000294179911287_318302356.0Coiled coilOntology_term=ECO:0000255
TgeneSTX5chr11:62566011chr11:62575100ENST00000294179911287_318302356.0Coiled coilOntology_term=ECO:0000255
TgeneSTX5chr11:62563759chr11:62575100ENST00000294179911263_325302356.0Domaint-SNARE coiled-coil homology
TgeneSTX5chr11:62563931chr11:62575099ENST00000294179911263_325302356.0Domaint-SNARE coiled-coil homology
TgeneSTX5chr11:62563932chr11:62575100ENST00000294179911263_325302356.0Domaint-SNARE coiled-coil homology
TgeneSTX5chr11:62566011chr11:62575100ENST00000294179911263_325302356.0Domaint-SNARE coiled-coil homology
TgeneSTX5chr11:62563759chr11:62575100ENST00000294179911245_247302356.0MotifIxM motif%3B signal for cargo packaging into COPII-coated vesicles
TgeneSTX5chr11:62563759chr11:62575100ENST00000394690911245_247248302.0MotifIxM motif%3B signal for cargo packaging into COPII-coated vesicles
TgeneSTX5chr11:62563931chr11:62575099ENST00000294179911245_247302356.0MotifIxM motif%3B signal for cargo packaging into COPII-coated vesicles
TgeneSTX5chr11:62563931chr11:62575099ENST00000394690911245_247248302.0MotifIxM motif%3B signal for cargo packaging into COPII-coated vesicles
TgeneSTX5chr11:62563932chr11:62575100ENST00000294179911245_247302356.0MotifIxM motif%3B signal for cargo packaging into COPII-coated vesicles
TgeneSTX5chr11:62563932chr11:62575100ENST00000394690911245_247248302.0MotifIxM motif%3B signal for cargo packaging into COPII-coated vesicles
TgeneSTX5chr11:62566011chr11:62575100ENST00000294179911245_247302356.0MotifIxM motif%3B signal for cargo packaging into COPII-coated vesicles
TgeneSTX5chr11:62566011chr11:62575100ENST00000394690911245_247248302.0MotifIxM motif%3B signal for cargo packaging into COPII-coated vesicles
TgeneSTX5chr11:62563759chr11:62575100ENST000002941799111_333302356.0Topological domainCytoplasmic
TgeneSTX5chr11:62563759chr11:62575100ENST000003946909111_333248302.0Topological domainCytoplasmic
TgeneSTX5chr11:62563931chr11:62575099ENST000002941799111_333302356.0Topological domainCytoplasmic
TgeneSTX5chr11:62563931chr11:62575099ENST000003946909111_333248302.0Topological domainCytoplasmic
TgeneSTX5chr11:62563932chr11:62575100ENST000002941799111_333302356.0Topological domainCytoplasmic
TgeneSTX5chr11:62563932chr11:62575100ENST000003946909111_333248302.0Topological domainCytoplasmic
TgeneSTX5chr11:62566011chr11:62575100ENST000002941799111_333302356.0Topological domainCytoplasmic
TgeneSTX5chr11:62566011chr11:62575100ENST000003946909111_333248302.0Topological domainCytoplasmic


Top

Fusion Gene Sequence for NXF1-STX5


check button For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. To have fusion amino acid sequence, we ran ORFfinder and chose the longest ORF among the all predicted ones.

Top

Fusion Gene PPI Analysis for NXF1-STX5


check button Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in

ChiPPI page.


check button Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160)
HgeneHgene's interactorsTgeneTgene's interactors


check button - Retained PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenStill interaction with
HgeneNXF1chr11:62563759chr11:62575100ENST00000294172-15212_198448.3333333333333620.0ALYREF/THOC4 and LUZP4
HgeneNXF1chr11:62563759chr11:62575100ENST00000531709-14202_1981048.6666666666667380.6666666666667ALYREF/THOC4 and LUZP4
HgeneNXF1chr11:62563759chr11:62575100ENST00000532297-16222_198448.3333333333333620.0ALYREF/THOC4 and LUZP4
HgeneNXF1chr11:62563931chr11:62575099ENST00000294172-14212_198428.6666666666667620.0ALYREF/THOC4 and LUZP4
HgeneNXF1chr11:62563931chr11:62575099ENST00000531709-13202_1981029.0380.6666666666667ALYREF/THOC4 and LUZP4
HgeneNXF1chr11:62563931chr11:62575099ENST00000532297-15222_198428.6666666666667620.0ALYREF/THOC4 and LUZP4
HgeneNXF1chr11:62563932chr11:62575100ENST00000294172-14212_198428.6666666666667620.0ALYREF/THOC4 and LUZP4
HgeneNXF1chr11:62563932chr11:62575100ENST00000531709-13202_1981029.0380.6666666666667ALYREF/THOC4 and LUZP4
HgeneNXF1chr11:62563932chr11:62575100ENST00000532297-15222_198428.6666666666667620.0ALYREF/THOC4 and LUZP4
HgeneNXF1chr11:62566011chr11:62575100ENST00000294172-11212_198351.0620.0ALYREF/THOC4 and LUZP4
HgeneNXF1chr11:62566011chr11:62575100ENST00000531709-10202_198951.3333333333334380.6666666666667ALYREF/THOC4 and LUZP4
HgeneNXF1chr11:62566011chr11:62575100ENST00000532297-12222_198351.0620.0ALYREF/THOC4 and LUZP4


check button - Lost PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with
HgeneNXF1chr11:62563759chr11:62575100ENST00000439713-1102_1980357.0ALYREF/THOC4 and LUZP4
HgeneNXF1chr11:62563931chr11:62575099ENST00000439713-1102_1980357.0ALYREF/THOC4 and LUZP4
HgeneNXF1chr11:62563932chr11:62575100ENST00000439713-1102_1980357.0ALYREF/THOC4 and LUZP4
HgeneNXF1chr11:62566011chr11:62575100ENST00000439713-1102_1980357.0ALYREF/THOC4 and LUZP4


check button - Retained PPIs, but lost function due to frame-shift fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


Top

Related Drugs for NXF1-STX5


check button Drugs targeting genes involved in this fusion gene.
(DrugBank Version 5.1.8 2021-05-08)
PartnerGeneUniProtAccDrugBank IDDrug nameDrug activityDrug typeDrug status

Top

Related Diseases for NXF1-STX5


check button Diseases associated with fusion partners.
(DisGeNet 4.0)
PartnerGeneDisease IDDisease name# pubmedsSource