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Center for Computational Systems Medicine
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Fusion Gene Summary

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Fusion Gene ORF analysis

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Fusion Genomic Features

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Fusion Protein Features

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Fusion Gene Sequence

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Fusion Gene PPI analysis

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Related Drugs

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Related Diseases

Fusion gene:OBFC1-COL17A1 (FusionGDB2 ID:61301)

Fusion Gene Summary for OBFC1-COL17A1

check button Fusion gene summary
Fusion gene informationFusion gene name: OBFC1-COL17A1
Fusion gene ID: 61301
HgeneTgene
Gene symbol

OBFC1

COL17A1

Gene ID

79991

1308

Gene nameSTN1 subunit of CST complexcollagen type XVII alpha 1 chain
SynonymsAAF-44|AAF44|OBFC1|RPA-32|bA541N10.2BA16H23.2|BP180|BPA-2|BPAG2|ERED|LAD-1
Cytomap

10q24.33

10q25.1

Type of geneprotein-codingprotein-coding
DescriptionCST complex subunit STN1STN1, CST complex subunitalpha accessory factor 44oligonucleotide/oligosaccharide binding fold containing 1oligonucleotide/oligosaccharide-binding fold-containing protein 1replication protein A 32 kDa subunitsuppressor of cdccollagen alpha-1(XVII) chain180 kDa bullous pemphigoid antigen 2alpha 1 type XVII collagenbA16H23.2 (collagen, type XVII, alpha 1 (BP180))bullous pemphigoid antigen 2 (180kD)collagen XVII, alpha-1 polypeptidecollagen, type XVII, alpha 1type XVII co
Modification date2020031320200313
UniProtAcc.

Q9UMD9

Ensembl transtripts involved in fusion geneENST00000224950, ENST00000369764, 
ENST00000466828, 		ENST00000393211, 
ENST00000480127, ENST00000353479, 
ENST00000369733, 
Fusion gene scores* DoF score3 X 4 X 3=364 X 5 X 5=100
# samples 46
** MAII scorelog2(4/36*10)=0.15200309344505
effective Gene in Pan-Cancer Fusion Genes (eGinPCFGs).
DoF>8 and MAII>0		log2(6/100*10)=-0.736965594166206
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0
Context

PubMed: OBFC1 [Title/Abstract] AND COL17A1 [Title/Abstract] AND fusion [Title/Abstract]

Most frequent breakpointOBFC1(105648830)-COL17A1(105795321), # samples:2
Anticipated loss of major functional domain due to fusion event.OBFC1-COL17A1 seems lost the major protein functional domain in Hgene partner, which is a essential gene due to the frame-shifted ORF.
OBFC1-COL17A1 seems lost the major protein functional domain in Tgene partner, which is a essential gene due to the frame-shifted ORF.
* DoF score (Degree of Frequency) = # partners X # break points X # cancer types
** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)

check button Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez
PartnerGeneGO IDGO termPubMed ID
HgeneOBFC1

GO:0032211

negative regulation of telomere maintenance via telomerase

22763445

TgeneCOL17A1

GO:0031581

hemidesmosome assembly

12482924


check buttonFusion gene breakpoints across OBFC1 (5'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check buttonFusion gene breakpoints across COL17A1 (3'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check button Fusion gene information from two resources (ChiTars 5.0 and ChimerDB 4.0)
* All genome coordinats were lifted-over on hg19.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
SourceDiseaseSampleHgeneHchrHbpHstrandTgeneTchrTbpTstrand
ChimerDB4STADTCGA-VQ-A925-01AOBFC1chr10

105648830

-COL17A1chr10

105795321

-
ChimerDB4STADTCGA-VQ-A925OBFC1chr10

105648829

-COL17A1chr10

105795321

-


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Fusion Gene ORF analysis for OBFC1-COL17A1

check button Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
ORFHenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrand
5CDS-intronENST00000224950ENST00000393211OBFC1chr10

105648830

-COL17A1chr10

105795321

-
5CDS-intronENST00000224950ENST00000393211OBFC1chr10

105648829

-COL17A1chr10

105795321

-
5CDS-intronENST00000224950ENST00000480127OBFC1chr10

105648830

-COL17A1chr10

105795321

-
5CDS-intronENST00000224950ENST00000480127OBFC1chr10

105648829

-COL17A1chr10

105795321

-
5CDS-intronENST00000369764ENST00000393211OBFC1chr10

105648830

-COL17A1chr10

105795321

-
5CDS-intronENST00000369764ENST00000393211OBFC1chr10

105648829

-COL17A1chr10

105795321

-
5CDS-intronENST00000369764ENST00000480127OBFC1chr10

105648830

-COL17A1chr10

105795321

-
5CDS-intronENST00000369764ENST00000480127OBFC1chr10

105648829

-COL17A1chr10

105795321

-
5UTR-3CDSENST00000466828ENST00000353479OBFC1chr10

105648830

-COL17A1chr10

105795321

-
5UTR-3CDSENST00000466828ENST00000353479OBFC1chr10

105648829

-COL17A1chr10

105795321

-
5UTR-3CDSENST00000466828ENST00000369733OBFC1chr10

105648830

-COL17A1chr10

105795321

-
5UTR-3CDSENST00000466828ENST00000369733OBFC1chr10

105648829

-COL17A1chr10

105795321

-
5UTR-intronENST00000466828ENST00000393211OBFC1chr10

105648830

-COL17A1chr10

105795321

-
5UTR-intronENST00000466828ENST00000393211OBFC1chr10

105648829

-COL17A1chr10

105795321

-
5UTR-intronENST00000466828ENST00000480127OBFC1chr10

105648830

-COL17A1chr10

105795321

-
5UTR-intronENST00000466828ENST00000480127OBFC1chr10

105648829

-COL17A1chr10

105795321

-
Frame-shiftENST00000224950ENST00000353479OBFC1chr10

105648830

-COL17A1chr10

105795321

-
Frame-shiftENST00000224950ENST00000353479OBFC1chr10

105648829

-COL17A1chr10

105795321

-
Frame-shiftENST00000224950ENST00000369733OBFC1chr10

105648830

-COL17A1chr10

105795321

-
Frame-shiftENST00000224950ENST00000369733OBFC1chr10

105648829

-COL17A1chr10

105795321

-
In-frameENST00000369764ENST00000353479OBFC1chr10

105648830

-COL17A1chr10

105795321

-
In-frameENST00000369764ENST00000353479OBFC1chr10

105648829

-COL17A1chr10

105795321

-
In-frameENST00000369764ENST00000369733OBFC1chr10

105648830

-COL17A1chr10

105795321

-
In-frameENST00000369764ENST00000369733OBFC1chr10

105648829

-COL17A1chr10

105795321

-

check buttonORFfinder result based on the fusion transcript sequence of in-frame fusion genes.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandSeq length
(transcript)		BP loci
(transcript)		Predicted start
(transcript)		Predicted stop
(transcript)		Seq length
(amino acids)
ENST00000369764OBFC1chr10105648829-ENST00000369733COL17A1chr10105795321-29381024721988638
ENST00000369764OBFC1chr10105648829-ENST00000353479COL17A1chr10105795321-30491024722099675
ENST00000369764OBFC1chr10105648830-ENST00000369733COL17A1chr10105795321-29381024721988638
ENST00000369764OBFC1chr10105648830-ENST00000353479COL17A1chr10105795321-30491024722099675

check buttonDeepORF prediction of the coding potential based on the fusion transcript sequence of in-frame fusion genes. DeepORF is a coding potential classifier based on convolutional neural network by comparing the real Ribo-seq data. If the no-coding score < 0.5 and coding score > 0.5, then the in-frame fusion transcript is predicted as being likely translated.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandNo-coding scoreCoding score
ENST00000369764ENST00000369733OBFC1chr10105648829-COL17A1chr10105795321-0.0077318720.99226815
ENST00000369764ENST00000353479OBFC1chr10105648829-COL17A1chr10105795321-0.0075128210.9924872
ENST00000369764ENST00000369733OBFC1chr10105648830-COL17A1chr10105795321-0.0077318720.99226815
ENST00000369764ENST00000353479OBFC1chr10105648830-COL17A1chr10105795321-0.0075128210.9924872

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Fusion Genomic Features for OBFC1-COL17A1


check buttonFusionAI prediction of the potential fusion gene breakpoint based on the pre-mature RNA sequence context (+/- 5kb of individual partner genes, total 20kb length sequence). FusionAI is a fusion gene breakpoint classifier based on convolutional neural network by comparing the fusion positive and negative sequence context of ~ 20K fusion gene data. From here, we can have the relative potentency of the 20K genomic sequence how individual sequnce will be likely used as the gene fusion breakpoints.
HgeneHchrHbpHstrandTgeneTchrTbpTstrand1-pp (fusion gene breakpoint)

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions. We integrated a total of 44 different types of human genomic feature loci information across five big categories including virus integration sites, repeats, structural variants, chromatin states, and gene expression regulation. More details are in help page.
genomic feature

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions that are ovelapped with the top 1% feature importance score regions. More details are in help page.

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Fusion Protein Features for OBFC1-COL17A1


check button Four levels of functional features of fusion genes
Go to FGviewer search page for the most frequent breakpoint (https://ccsmweb.uth.edu/FGviewer/chr10:105648830/chr10:105795321)
- FGviewer provides the online visualization of the retention search of the protein functional features across DNA, RNA, protein, and pathological levels.
- How to search
1. Put your fusion gene symbol.
2. Press the tab key until there will be shown the breakpoint information filled.
4. Go down and press 'Search' tab twice.
4. Go down to have the hyperlink of the search result.
5. Click the hyperlink.
6. See the FGviewer result for your fusion gene.
FGviewer

check buttonMain function of each fusion partner protein. (from UniProt)
HgeneTgene
.COL17A1

Q9UMD9

FUNCTION: Transcriptional activator which is required for calcium-dependent dendritic growth and branching in cortical neurons. Recruits CREB-binding protein (CREBBP) to nuclear bodies. Component of the CREST-BRG1 complex, a multiprotein complex that regulates promoter activation by orchestrating a calcium-dependent release of a repressor complex and a recruitment of an activator complex. In resting neurons, transcription of the c-FOS promoter is inhibited by BRG1-dependent recruitment of a phospho-RB1-HDAC1 repressor complex. Upon calcium influx, RB1 is dephosphorylated by calcineurin, which leads to release of the repressor complex. At the same time, there is increased recruitment of CREBBP to the promoter by a CREST-dependent mechanism, which leads to transcriptional activation. The CREST-BRG1 complex also binds to the NR2B promoter, and activity-dependent induction of NR2B expression involves a release of HDAC1 and recruitment of CREBBP (By similarity). {ECO:0000250}.FUNCTION: May play a role in the integrity of hemidesmosome and the attachment of basal keratinocytes to the underlying basement membrane.; FUNCTION: The 120 kDa linear IgA disease antigen is an anchoring filament component involved in dermal-epidermal cohesion. Is the target of linear IgA bullous dermatosis autoantibodies.

check buttonRetention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at

download page


* Minus value of BPloci means that the break pointn is located before the CDS.
- In-frame and retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneOBFC1chr10:105648829chr10:105795321ENST00000224950-91057_155316369.0DNA bindingNote=OB
HgeneOBFC1chr10:105648829chr10:105795321ENST00000369764-8957_155316369.0DNA bindingNote=OB
HgeneOBFC1chr10:105648830chr10:105795321ENST00000224950-91057_155316369.0DNA bindingNote=OB
HgeneOBFC1chr10:105648830chr10:105795321ENST00000369764-8957_155316369.0DNA bindingNote=OB
HgeneOBFC1chr10:105648829chr10:105795321ENST00000224950-910191_295316369.0RegionNote=Winged helix-turn-helix (wHTH) 1
HgeneOBFC1chr10:105648829chr10:105795321ENST00000369764-89191_295316369.0RegionNote=Winged helix-turn-helix (wHTH) 1
HgeneOBFC1chr10:105648830chr10:105795321ENST00000224950-910191_295316369.0RegionNote=Winged helix-turn-helix (wHTH) 1
HgeneOBFC1chr10:105648830chr10:105795321ENST00000369764-89191_295316369.0RegionNote=Winged helix-turn-helix (wHTH) 1
TgeneCOL17A1chr10:105648829chr10:105795321ENST0000035347947561483_149711391498.0RegionNote=Nonhelical region (NC1)
TgeneCOL17A1chr10:105648829chr10:105795321ENST0000036973344521483_149710941416.0RegionNote=Nonhelical region (NC1)
TgeneCOL17A1chr10:105648830chr10:105795321ENST0000035347947561483_149711391498.0RegionNote=Nonhelical region (NC1)
TgeneCOL17A1chr10:105648830chr10:105795321ENST0000036973344521483_149710941416.0RegionNote=Nonhelical region (NC1)

- In-frame and not-retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneOBFC1chr10:105648829chr10:105795321ENST00000224950-910296_368316369.0RegionNote=Winged helix-turn-helix (wHTH) 2
HgeneOBFC1chr10:105648829chr10:105795321ENST00000369764-89296_368316369.0RegionNote=Winged helix-turn-helix (wHTH) 2
HgeneOBFC1chr10:105648830chr10:105795321ENST00000224950-910296_368316369.0RegionNote=Winged helix-turn-helix (wHTH) 2
HgeneOBFC1chr10:105648830chr10:105795321ENST00000369764-89296_368316369.0RegionNote=Winged helix-turn-helix (wHTH) 2
TgeneCOL17A1chr10:105648829chr10:105795321ENST0000035347947561_56611391498.0RegionNote=Nonhelical region (NC16)
TgeneCOL17A1chr10:105648829chr10:105795321ENST000003534794756567_148211391498.0RegionNote=Triple-helical region
TgeneCOL17A1chr10:105648829chr10:105795321ENST0000036973344521_56610941416.0RegionNote=Nonhelical region (NC16)
TgeneCOL17A1chr10:105648829chr10:105795321ENST000003697334452567_148210941416.0RegionNote=Triple-helical region
TgeneCOL17A1chr10:105648830chr10:105795321ENST0000035347947561_56611391498.0RegionNote=Nonhelical region (NC16)
TgeneCOL17A1chr10:105648830chr10:105795321ENST000003534794756567_148211391498.0RegionNote=Triple-helical region
TgeneCOL17A1chr10:105648830chr10:105795321ENST0000036973344521_56610941416.0RegionNote=Nonhelical region (NC16)
TgeneCOL17A1chr10:105648830chr10:105795321ENST000003697334452567_148210941416.0RegionNote=Triple-helical region
TgeneCOL17A1chr10:105648829chr10:105795321ENST0000035347947561_46711391498.0Topological domainCytoplasmic
TgeneCOL17A1chr10:105648829chr10:105795321ENST000003534794756489_149711391498.0Topological domainExtracellular
TgeneCOL17A1chr10:105648829chr10:105795321ENST0000036973344521_46710941416.0Topological domainCytoplasmic
TgeneCOL17A1chr10:105648829chr10:105795321ENST000003697334452489_149710941416.0Topological domainExtracellular
TgeneCOL17A1chr10:105648830chr10:105795321ENST0000035347947561_46711391498.0Topological domainCytoplasmic
TgeneCOL17A1chr10:105648830chr10:105795321ENST000003534794756489_149711391498.0Topological domainExtracellular
TgeneCOL17A1chr10:105648830chr10:105795321ENST0000036973344521_46710941416.0Topological domainCytoplasmic
TgeneCOL17A1chr10:105648830chr10:105795321ENST000003697334452489_149710941416.0Topological domainExtracellular
TgeneCOL17A1chr10:105648829chr10:105795321ENST000003534794756468_48811391498.0TransmembraneHelical%3B Signal-anchor for type II membrane protein
TgeneCOL17A1chr10:105648829chr10:105795321ENST000003697334452468_48810941416.0TransmembraneHelical%3B Signal-anchor for type II membrane protein
TgeneCOL17A1chr10:105648830chr10:105795321ENST000003534794756468_48811391498.0TransmembraneHelical%3B Signal-anchor for type II membrane protein
TgeneCOL17A1chr10:105648830chr10:105795321ENST000003697334452468_48810941416.0TransmembraneHelical%3B Signal-anchor for type II membrane protein


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Fusion Gene Sequence for OBFC1-COL17A1


check button For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. To have fusion amino acid sequence, we ran ORFfinder and chose the longest ORF among the all predicted ones.
>61301_61301_1_OBFC1-COL17A1_OBFC1_chr10_105648829_ENST00000369764_COL17A1_chr10_105795321_ENST00000353479_length(transcript)=3049nt_BP=1024nt
GTGTCCCATCTAGATGCTTGACTCAGTGATGCAGAACCTTTCAGAGTTAGCTGGAAGCCACAGCCCTGCCTCTTGATGCAGCCTGGATCC
AGCCGGTGTGAAGAGGAGACCCCTTCCCTCTTGTGGGGTTTGGATCCTGTGTTTCTAGCCTTTGCAAAACTCTACATCAGGGATATCCTG
GACATGAAGGAGTCCCGCCAGGTGCCAGGTGTATTTTTGTACAATGGACATCCAATAAAACAGGTAGATGTCTTGGGAACTGTCATTGGA
GTGAGAGAAAGAGATGCTTTCTACAGTTATGGAGTGGATGACAGCACTGGAGTTATAAACTGCATCTGCTGGAAAAAGTTGAATACTGAG
TCTGTATCAGCTGCTCCAAGTGCAGCAAGAGAGCTCAGCTTAACCTCACAACTTAAGAAGCTACAAGAGACCATTGAGCAGAAAACAAAG
ATAGAGATCGGGGACACGATCCGAGTCAGAGGCAGTATCCGCACATACAGAGAAGAGCGAGAGATTCATGCCACCACTTACTATAAAGTG
GACGACCCAGTGTGGAACATTCAAATTGCAAGGATGCTTGAGCTGCCCACTATCTACAGGAAAGTTTATGACCAGCCTTTTCACAGCTCA
GCCCTAGAGAAAGAAGAGGCACTAAGCAATCCAGGCGCCCTGGACCTCCCCAGTCTCACGAGTTTGCTGAGTGAAAAAGCCAAAGAATTC
CTCATGGAGAACAGAGTGCAGAGCTTTTACCAGCAGGAGCTGGAAATGGTGGAGTCTTTGCTGTCCCTTGCCAATCAGCCTGTGATTCAC
AGTGCCTCCTCCGACCAAGTGAATTTTAAGAAGGACACCACTTCCAAGGCAATTCATAGTATATTTAAGAATGCTATACAACTGCTGCAG
GAAAAAGGACTTGTTTTCCAGAAAGATGATGGTTTTGATAACCTATACTATGTAACCAGAGAAGACAAAGACCTGCACAGAAAGATCCAC
CGGATCATTCAGCAGGACTGCCAGAAACCAAATCGTTCTGGGATCAGCATTGGGCTTCCTGGTCCCCCGGGGCCCCCTGGCTTGCCGGGA
ACCTCCTATGAGGAGCTCCTCTCCTTGCTGCGAGGGTCTGAATTCAGAGGCATCGTTGGACCCCCAGGTCCCCCGGGTCCACCAGGGATC
CCAGGCAATGTGTGGTCCAGCATCAGCGTGGAGGACCTCTCGTCTTACTTACATACTGCCGGCTTGTCATTCATCCCAGGCCCTCCAGGA
CCTCCTGGTCCCCCAGGGCCTCGAGGGCCCCCGGGTGTCTCAGGAGCCCTGGCAACCTATGCAGCTGAAAACAGCGACAGCTTCCGGAGC
GAGCTGATCAGCTACCTCACAAGTCCTGATGTGCGCAGCTTCATTGTTGGCCCCCCAGGCCCTCCTGGGCCGCAGGGACCCCCTGGGGAC
AGCCGCCTCCTGTCCACGGATGCCTCCCACAGTCGGGGTAGCAGCTCCTCCTCACACAGCTCATCTGTCAGGCGGGGCAGCTCCTACAGC
TCTTCCATGAGCACAGGAGGAGGTGGTGCAGGCTCCCTGGGTGCAGGCGGTGCCTTTGGTGAAGCTGCAGGAGACAGGGGTCCCTATGGC
ACTGACATCGGCCCAGGCGGAGGCTATGGGGCAGCAGCAGAAGGCGGCATGTATGCTGGCAATGGCGGACTATTGGGAGCTGACTTTGCT
GGAGATCTGGATTACAATGAGCTGGCTGTGAGGGTGTCAGAGAGCATGCAGCGTCAGGGCCTACTGCAAGGGATGGCCTACACTGTCCAG
GGCCCACCAGGCCAGCCTGGGCCACAGGGGCCACCCGGCATCAGCAAGGTCTTCTCTGCCTACAGCAACGTGACTGCGGACCTCATGGAC
TTCTTCCAAACTTATGGAGCCATTCAAGGACCCCCTGGGCAAAAAGGAGAGATGGGCACTCCAGGACCCAAAGGTGACAGGGGCCCTGCT
GGGCCACCAGGTCATCCTGGGCCACCTGGCCCTCGAGGACACAAGGGAGAAAAAGGAGACAAAGGTGACCAAGTCTATGCTGGGCGGAGA
AGGAGAAGAAGTATTGCTGTCAAGCCGTGAGCTAGCCATGGCAGGACAGCTCCTGGACCAGGTCTCATAATGCATGTGGCACTTAGGTCC
AAGGTCTCCAGAGGGTGAAAGCTGGAGTCTGTCAATGTCCTACTGAGACAGCACAGCCAACCTAGCTAGCAACATTTGTTTTAGTCTGAA
CAATATATACTTATAGAATTCAGTCAAAGATACACAATCTGAAACAGCTTCATGGGGTGGACTCTAACAGTAGTTGCAATGTTTTAGAAT
GAGACTTACTTCTCTGCTATCTAGATCTGAACTCCTTGGCTTCTTTACTTAGTTCAAGCCCCAGCCTAGGAAAGCCAGTTACATAAAAGT
TGGCTCAGGAGTCTTAGAGCTTTACCTAAATATGAGCCCAGAAAACGGAGGATGGGGGTGGGGCGCCTTCCTGGAGGTGACACTTGATGG
GGGTGTGTTCTGGTTACTGTTCTAAGGCTGTGCCATCAGCTCCTTCCTCCCCTGTTCATTCTGCATTCTCTAGTCAGTTGGCTAAGAAGT
GACTCTTGCAACTAAAAAAATTAAGAAATTCACTTCCCCTCTAGGAGGTGATGATAGGGTTTCTAATGGTTATATGTATATCACATTCCC
ATTTGCTTAGAAAGTCTGATTGTAGCTATGATTGTCCGTAGGCCCATACTAGAGTTCATGGATATGTTATACTGAACCAGGCCAGAGCAA
ACAGAAAAAGAAGGTTGAGGGCAATGGACAAGGAAGGAATAAAGGGAGAAGAGGGAAAACAGAAAACCTGATGCTGGGGACACAGCATCA
GCTCAAGACGTCACCCTCCATTCTGCACTCAGAAAATGGCACTTGGGGGACTGGGCGCAGTTGGTCTTTAACCACTTTTCAATGTCTAAA

>61301_61301_1_OBFC1-COL17A1_OBFC1_chr10_105648829_ENST00000369764_COL17A1_chr10_105795321_ENST00000353479_length(amino acids)=675AA_BP=355
MMQPGSSRCEEETPSLLWGLDPVFLAFAKLYIRDILDMKESRQVPGVFLYNGHPIKQVDVLGTVIGVRERDAFYSYGVDDSTGVINCICW
KKLNTESVSAAPSAARELSLTSQLKKLQETIEQKTKIEIGDTIRVRGSIRTYREEREIHATTYYKVDDPVWNIQIARMLELPTIYRKVYD
QPFHSSALEKEEALSNPGALDLPSLTSLLSEKAKEFLMENRVQSFYQQELEMVESLLSLANQPVIHSASSDQVNFKKDTTSKAIHSIFKN
AIQLLQEKGLVFQKDDGFDNLYYVTREDKDLHRKIHRIIQQDCQKPNRSGISIGLPGPPGPPGLPGTSYEELLSLLRGSEFRGIVGPPGP
PGPPGIPGNVWSSISVEDLSSYLHTAGLSFIPGPPGPPGPPGPRGPPGVSGALATYAAENSDSFRSELISYLTSPDVRSFIVGPPGPPGP
QGPPGDSRLLSTDASHSRGSSSSSHSSSVRRGSSYSSSMSTGGGGAGSLGAGGAFGEAAGDRGPYGTDIGPGGGYGAAAEGGMYAGNGGL
LGADFAGDLDYNELAVRVSESMQRQGLLQGMAYTVQGPPGQPGPQGPPGISKVFSAYSNVTADLMDFFQTYGAIQGPPGQKGEMGTPGPK

--------------------------------------------------------------
>61301_61301_2_OBFC1-COL17A1_OBFC1_chr10_105648829_ENST00000369764_COL17A1_chr10_105795321_ENST00000369733_length(transcript)=2938nt_BP=1024nt
GTGTCCCATCTAGATGCTTGACTCAGTGATGCAGAACCTTTCAGAGTTAGCTGGAAGCCACAGCCCTGCCTCTTGATGCAGCCTGGATCC
AGCCGGTGTGAAGAGGAGACCCCTTCCCTCTTGTGGGGTTTGGATCCTGTGTTTCTAGCCTTTGCAAAACTCTACATCAGGGATATCCTG
GACATGAAGGAGTCCCGCCAGGTGCCAGGTGTATTTTTGTACAATGGACATCCAATAAAACAGGTAGATGTCTTGGGAACTGTCATTGGA
GTGAGAGAAAGAGATGCTTTCTACAGTTATGGAGTGGATGACAGCACTGGAGTTATAAACTGCATCTGCTGGAAAAAGTTGAATACTGAG
TCTGTATCAGCTGCTCCAAGTGCAGCAAGAGAGCTCAGCTTAACCTCACAACTTAAGAAGCTACAAGAGACCATTGAGCAGAAAACAAAG
ATAGAGATCGGGGACACGATCCGAGTCAGAGGCAGTATCCGCACATACAGAGAAGAGCGAGAGATTCATGCCACCACTTACTATAAAGTG
GACGACCCAGTGTGGAACATTCAAATTGCAAGGATGCTTGAGCTGCCCACTATCTACAGGAAAGTTTATGACCAGCCTTTTCACAGCTCA
GCCCTAGAGAAAGAAGAGGCACTAAGCAATCCAGGCGCCCTGGACCTCCCCAGTCTCACGAGTTTGCTGAGTGAAAAAGCCAAAGAATTC
CTCATGGAGAACAGAGTGCAGAGCTTTTACCAGCAGGAGCTGGAAATGGTGGAGTCTTTGCTGTCCCTTGCCAATCAGCCTGTGATTCAC
AGTGCCTCCTCCGACCAAGTGAATTTTAAGAAGGACACCACTTCCAAGGCAATTCATAGTATATTTAAGAATGCTATACAACTGCTGCAG
GAAAAAGGACTTGTTTTCCAGAAAGATGATGGTTTTGATAACCTATACTATGTAACCAGAGAAGACAAAGACCTGCACAGAAAGATCCAC
CGGATCATTCAGCAGGACTGCCAGAAACCAAATCGTTCTGGGATCAGCATTGGGCTTCCTGGTCCCCCGGGGCCCCCTGGCTTGCCGGGA
ACCTCCTATGAGGAGCTCCTCTCCTTGCTGCGAGCTGCCGGCTTGTCATTCATCCCAGGCCCTCCAGGACCTCCTGGTCCCCCAGGGCCT
CGAGGGCCCCCGGGTGTCTCAGGAGCCCTGGCAACCTATGCAGCTGAAAACAGCGACAGCTTCCGGAGCGAGCTGATCAGCTACCTCACA
AGTCCTGATGTGCGCAGCTTCATTGTTGGCCCCCCAGGCCCTCCTGGGCCGCAGGGACCCCCTGGGGACAGCCGCCTCCTGTCCACGGAT
GCCTCCCACAGTCGGGGTAGCAGCTCCTCCTCACACAGCTCATCTGTCAGGCGGGGCAGCTCCTACAGCTCTTCCATGAGCACAGGAGGA
GGTGGTGCAGGCTCCCTGGGTGCAGGCGGTGCCTTTGGTGAAGCTGCAGGAGACAGGGGTCCCTATGGCACTGACATCGGCCCAGGCGGA
GGCTATGGGGCAGCAGCAGAAGGCGGCATGTATGCTGGCAATGGCGGACTATTGGGAGCTGACTTTGCTGGAGATCTGGATTACAATGAG
CTGGCTGTGAGGGTGTCAGAGAGCATGCAGCGTCAGGGCCTACTGCAAGGGATGGCCTACACTGTCCAGGGCCCACCAGGCCAGCCTGGG
CCACAGGGGCCACCCGGCATCAGCAAGGTCTTCTCTGCCTACAGCAACGTGACTGCGGACCTCATGGACTTCTTCCAAACTTATGGAGCC
ATTCAAGGACCCCCTGGGCAAAAAGGAGAGATGGGCACTCCAGGACCCAAAGGTGACAGGGGCCCTGCTGGGCCACCAGGTCATCCTGGG
CCACCTGGCCCTCGAGGACACAAGGGAGAAAAAGGAGACAAAGGTGACCAAGTCTATGCTGGGCGGAGAAGGAGAAGAAGTATTGCTGTC
AAGCCGTGAGCTAGCCATGGCAGGACAGCTCCTGGACCAGGTCTCATAATGCATGTGGCACTTAGGTCCAAGGTCTCCAGAGGGTGAAAG
CTGGAGTCTGTCAATGTCCTACTGAGACAGCACAGCCAACCTAGCTAGCAACATTTGTTTTAGTCTGAACAATATATACTTATAGAATTC
AGTCAAAGATACACAATCTGAAACAGCTTCATGGGGTGGACTCTAACAGTAGTTGCAATGTTTTAGAATGAGACTTACTTCTCTGCTATC
TAGATCTGAACTCCTTGGCTTCTTTACTTAGTTCAAGCCCCAGCCTAGGAAAGCCAGTTACATAAAAGTTGGCTCAGGAGTCTTAGAGCT
TTACCTAAATATGAGCCCAGAAAACGGAGGATGGGGGTGGGGCGCCTTCCTGGAGGTGACACTTGATGGGGGTGTGTTCTGGTTACTGTT
CTAAGGCTGTGCCATCAGCTCCTTCCTCCCCTGTTCATTCTGCATTCTCTAGTCAGTTGGCTAAGAAGTGACTCTTGCAACTAAAAAAAT
TAAGAAATTCACTTCCCCTCTAGGAGGTGATGATAGGGTTTCTAATGGTTATATGTATATCACATTCCCATTTGCTTAGAAAGTCTGATT
GTAGCTATGATTGTCCGTAGGCCCATACTAGAGTTCATGGATATGTTATACTGAACCAGGCCAGAGCAAACAGAAAAAGAAGGTTGAGGG
CAATGGACAAGGAAGGAATAAAGGGAGAAGAGGGAAAACAGAAAACCTGATGCTGGGGACACAGCATCAGCTCAAGACGTCACCCTCCAT
TCTGCACTCAGAAAATGGCACTTGGGGGACTGGGCGCAGTTGGTCTTTAACCACTTTTCAATGTCTAAAAACATTTGTTTGTGGTCTATA

>61301_61301_2_OBFC1-COL17A1_OBFC1_chr10_105648829_ENST00000369764_COL17A1_chr10_105795321_ENST00000369733_length(amino acids)=638AA_BP=324
MMQPGSSRCEEETPSLLWGLDPVFLAFAKLYIRDILDMKESRQVPGVFLYNGHPIKQVDVLGTVIGVRERDAFYSYGVDDSTGVINCICW
KKLNTESVSAAPSAARELSLTSQLKKLQETIEQKTKIEIGDTIRVRGSIRTYREEREIHATTYYKVDDPVWNIQIARMLELPTIYRKVYD
QPFHSSALEKEEALSNPGALDLPSLTSLLSEKAKEFLMENRVQSFYQQELEMVESLLSLANQPVIHSASSDQVNFKKDTTSKAIHSIFKN
AIQLLQEKGLVFQKDDGFDNLYYVTREDKDLHRKIHRIIQQDCQKPNRSGISIGLPGPPGPPGLPGTSYEELLSLLRAAGLSFIPGPPGP
PGPPGPRGPPGVSGALATYAAENSDSFRSELISYLTSPDVRSFIVGPPGPPGPQGPPGDSRLLSTDASHSRGSSSSSHSSSVRRGSSYSS
SMSTGGGGAGSLGAGGAFGEAAGDRGPYGTDIGPGGGYGAAAEGGMYAGNGGLLGADFAGDLDYNELAVRVSESMQRQGLLQGMAYTVQG
PPGQPGPQGPPGISKVFSAYSNVTADLMDFFQTYGAIQGPPGQKGEMGTPGPKGDRGPAGPPGHPGPPGPRGHKGEKGDKGDQVYAGRRR

--------------------------------------------------------------
>61301_61301_3_OBFC1-COL17A1_OBFC1_chr10_105648830_ENST00000369764_COL17A1_chr10_105795321_ENST00000353479_length(transcript)=3049nt_BP=1024nt
GTGTCCCATCTAGATGCTTGACTCAGTGATGCAGAACCTTTCAGAGTTAGCTGGAAGCCACAGCCCTGCCTCTTGATGCAGCCTGGATCC
AGCCGGTGTGAAGAGGAGACCCCTTCCCTCTTGTGGGGTTTGGATCCTGTGTTTCTAGCCTTTGCAAAACTCTACATCAGGGATATCCTG
GACATGAAGGAGTCCCGCCAGGTGCCAGGTGTATTTTTGTACAATGGACATCCAATAAAACAGGTAGATGTCTTGGGAACTGTCATTGGA
GTGAGAGAAAGAGATGCTTTCTACAGTTATGGAGTGGATGACAGCACTGGAGTTATAAACTGCATCTGCTGGAAAAAGTTGAATACTGAG
TCTGTATCAGCTGCTCCAAGTGCAGCAAGAGAGCTCAGCTTAACCTCACAACTTAAGAAGCTACAAGAGACCATTGAGCAGAAAACAAAG
ATAGAGATCGGGGACACGATCCGAGTCAGAGGCAGTATCCGCACATACAGAGAAGAGCGAGAGATTCATGCCACCACTTACTATAAAGTG
GACGACCCAGTGTGGAACATTCAAATTGCAAGGATGCTTGAGCTGCCCACTATCTACAGGAAAGTTTATGACCAGCCTTTTCACAGCTCA
GCCCTAGAGAAAGAAGAGGCACTAAGCAATCCAGGCGCCCTGGACCTCCCCAGTCTCACGAGTTTGCTGAGTGAAAAAGCCAAAGAATTC
CTCATGGAGAACAGAGTGCAGAGCTTTTACCAGCAGGAGCTGGAAATGGTGGAGTCTTTGCTGTCCCTTGCCAATCAGCCTGTGATTCAC
AGTGCCTCCTCCGACCAAGTGAATTTTAAGAAGGACACCACTTCCAAGGCAATTCATAGTATATTTAAGAATGCTATACAACTGCTGCAG
GAAAAAGGACTTGTTTTCCAGAAAGATGATGGTTTTGATAACCTATACTATGTAACCAGAGAAGACAAAGACCTGCACAGAAAGATCCAC
CGGATCATTCAGCAGGACTGCCAGAAACCAAATCGTTCTGGGATCAGCATTGGGCTTCCTGGTCCCCCGGGGCCCCCTGGCTTGCCGGGA
ACCTCCTATGAGGAGCTCCTCTCCTTGCTGCGAGGGTCTGAATTCAGAGGCATCGTTGGACCCCCAGGTCCCCCGGGTCCACCAGGGATC
CCAGGCAATGTGTGGTCCAGCATCAGCGTGGAGGACCTCTCGTCTTACTTACATACTGCCGGCTTGTCATTCATCCCAGGCCCTCCAGGA
CCTCCTGGTCCCCCAGGGCCTCGAGGGCCCCCGGGTGTCTCAGGAGCCCTGGCAACCTATGCAGCTGAAAACAGCGACAGCTTCCGGAGC
GAGCTGATCAGCTACCTCACAAGTCCTGATGTGCGCAGCTTCATTGTTGGCCCCCCAGGCCCTCCTGGGCCGCAGGGACCCCCTGGGGAC
AGCCGCCTCCTGTCCACGGATGCCTCCCACAGTCGGGGTAGCAGCTCCTCCTCACACAGCTCATCTGTCAGGCGGGGCAGCTCCTACAGC
TCTTCCATGAGCACAGGAGGAGGTGGTGCAGGCTCCCTGGGTGCAGGCGGTGCCTTTGGTGAAGCTGCAGGAGACAGGGGTCCCTATGGC
ACTGACATCGGCCCAGGCGGAGGCTATGGGGCAGCAGCAGAAGGCGGCATGTATGCTGGCAATGGCGGACTATTGGGAGCTGACTTTGCT
GGAGATCTGGATTACAATGAGCTGGCTGTGAGGGTGTCAGAGAGCATGCAGCGTCAGGGCCTACTGCAAGGGATGGCCTACACTGTCCAG
GGCCCACCAGGCCAGCCTGGGCCACAGGGGCCACCCGGCATCAGCAAGGTCTTCTCTGCCTACAGCAACGTGACTGCGGACCTCATGGAC
TTCTTCCAAACTTATGGAGCCATTCAAGGACCCCCTGGGCAAAAAGGAGAGATGGGCACTCCAGGACCCAAAGGTGACAGGGGCCCTGCT
GGGCCACCAGGTCATCCTGGGCCACCTGGCCCTCGAGGACACAAGGGAGAAAAAGGAGACAAAGGTGACCAAGTCTATGCTGGGCGGAGA
AGGAGAAGAAGTATTGCTGTCAAGCCGTGAGCTAGCCATGGCAGGACAGCTCCTGGACCAGGTCTCATAATGCATGTGGCACTTAGGTCC
AAGGTCTCCAGAGGGTGAAAGCTGGAGTCTGTCAATGTCCTACTGAGACAGCACAGCCAACCTAGCTAGCAACATTTGTTTTAGTCTGAA
CAATATATACTTATAGAATTCAGTCAAAGATACACAATCTGAAACAGCTTCATGGGGTGGACTCTAACAGTAGTTGCAATGTTTTAGAAT
GAGACTTACTTCTCTGCTATCTAGATCTGAACTCCTTGGCTTCTTTACTTAGTTCAAGCCCCAGCCTAGGAAAGCCAGTTACATAAAAGT
TGGCTCAGGAGTCTTAGAGCTTTACCTAAATATGAGCCCAGAAAACGGAGGATGGGGGTGGGGCGCCTTCCTGGAGGTGACACTTGATGG
GGGTGTGTTCTGGTTACTGTTCTAAGGCTGTGCCATCAGCTCCTTCCTCCCCTGTTCATTCTGCATTCTCTAGTCAGTTGGCTAAGAAGT
GACTCTTGCAACTAAAAAAATTAAGAAATTCACTTCCCCTCTAGGAGGTGATGATAGGGTTTCTAATGGTTATATGTATATCACATTCCC
ATTTGCTTAGAAAGTCTGATTGTAGCTATGATTGTCCGTAGGCCCATACTAGAGTTCATGGATATGTTATACTGAACCAGGCCAGAGCAA
ACAGAAAAAGAAGGTTGAGGGCAATGGACAAGGAAGGAATAAAGGGAGAAGAGGGAAAACAGAAAACCTGATGCTGGGGACACAGCATCA
GCTCAAGACGTCACCCTCCATTCTGCACTCAGAAAATGGCACTTGGGGGACTGGGCGCAGTTGGTCTTTAACCACTTTTCAATGTCTAAA

>61301_61301_3_OBFC1-COL17A1_OBFC1_chr10_105648830_ENST00000369764_COL17A1_chr10_105795321_ENST00000353479_length(amino acids)=675AA_BP=355
MMQPGSSRCEEETPSLLWGLDPVFLAFAKLYIRDILDMKESRQVPGVFLYNGHPIKQVDVLGTVIGVRERDAFYSYGVDDSTGVINCICW
KKLNTESVSAAPSAARELSLTSQLKKLQETIEQKTKIEIGDTIRVRGSIRTYREEREIHATTYYKVDDPVWNIQIARMLELPTIYRKVYD
QPFHSSALEKEEALSNPGALDLPSLTSLLSEKAKEFLMENRVQSFYQQELEMVESLLSLANQPVIHSASSDQVNFKKDTTSKAIHSIFKN
AIQLLQEKGLVFQKDDGFDNLYYVTREDKDLHRKIHRIIQQDCQKPNRSGISIGLPGPPGPPGLPGTSYEELLSLLRGSEFRGIVGPPGP
PGPPGIPGNVWSSISVEDLSSYLHTAGLSFIPGPPGPPGPPGPRGPPGVSGALATYAAENSDSFRSELISYLTSPDVRSFIVGPPGPPGP
QGPPGDSRLLSTDASHSRGSSSSSHSSSVRRGSSYSSSMSTGGGGAGSLGAGGAFGEAAGDRGPYGTDIGPGGGYGAAAEGGMYAGNGGL
LGADFAGDLDYNELAVRVSESMQRQGLLQGMAYTVQGPPGQPGPQGPPGISKVFSAYSNVTADLMDFFQTYGAIQGPPGQKGEMGTPGPK

--------------------------------------------------------------
>61301_61301_4_OBFC1-COL17A1_OBFC1_chr10_105648830_ENST00000369764_COL17A1_chr10_105795321_ENST00000369733_length(transcript)=2938nt_BP=1024nt
GTGTCCCATCTAGATGCTTGACTCAGTGATGCAGAACCTTTCAGAGTTAGCTGGAAGCCACAGCCCTGCCTCTTGATGCAGCCTGGATCC
AGCCGGTGTGAAGAGGAGACCCCTTCCCTCTTGTGGGGTTTGGATCCTGTGTTTCTAGCCTTTGCAAAACTCTACATCAGGGATATCCTG
GACATGAAGGAGTCCCGCCAGGTGCCAGGTGTATTTTTGTACAATGGACATCCAATAAAACAGGTAGATGTCTTGGGAACTGTCATTGGA
GTGAGAGAAAGAGATGCTTTCTACAGTTATGGAGTGGATGACAGCACTGGAGTTATAAACTGCATCTGCTGGAAAAAGTTGAATACTGAG
TCTGTATCAGCTGCTCCAAGTGCAGCAAGAGAGCTCAGCTTAACCTCACAACTTAAGAAGCTACAAGAGACCATTGAGCAGAAAACAAAG
ATAGAGATCGGGGACACGATCCGAGTCAGAGGCAGTATCCGCACATACAGAGAAGAGCGAGAGATTCATGCCACCACTTACTATAAAGTG
GACGACCCAGTGTGGAACATTCAAATTGCAAGGATGCTTGAGCTGCCCACTATCTACAGGAAAGTTTATGACCAGCCTTTTCACAGCTCA
GCCCTAGAGAAAGAAGAGGCACTAAGCAATCCAGGCGCCCTGGACCTCCCCAGTCTCACGAGTTTGCTGAGTGAAAAAGCCAAAGAATTC
CTCATGGAGAACAGAGTGCAGAGCTTTTACCAGCAGGAGCTGGAAATGGTGGAGTCTTTGCTGTCCCTTGCCAATCAGCCTGTGATTCAC
AGTGCCTCCTCCGACCAAGTGAATTTTAAGAAGGACACCACTTCCAAGGCAATTCATAGTATATTTAAGAATGCTATACAACTGCTGCAG
GAAAAAGGACTTGTTTTCCAGAAAGATGATGGTTTTGATAACCTATACTATGTAACCAGAGAAGACAAAGACCTGCACAGAAAGATCCAC
CGGATCATTCAGCAGGACTGCCAGAAACCAAATCGTTCTGGGATCAGCATTGGGCTTCCTGGTCCCCCGGGGCCCCCTGGCTTGCCGGGA
ACCTCCTATGAGGAGCTCCTCTCCTTGCTGCGAGCTGCCGGCTTGTCATTCATCCCAGGCCCTCCAGGACCTCCTGGTCCCCCAGGGCCT
CGAGGGCCCCCGGGTGTCTCAGGAGCCCTGGCAACCTATGCAGCTGAAAACAGCGACAGCTTCCGGAGCGAGCTGATCAGCTACCTCACA
AGTCCTGATGTGCGCAGCTTCATTGTTGGCCCCCCAGGCCCTCCTGGGCCGCAGGGACCCCCTGGGGACAGCCGCCTCCTGTCCACGGAT
GCCTCCCACAGTCGGGGTAGCAGCTCCTCCTCACACAGCTCATCTGTCAGGCGGGGCAGCTCCTACAGCTCTTCCATGAGCACAGGAGGA
GGTGGTGCAGGCTCCCTGGGTGCAGGCGGTGCCTTTGGTGAAGCTGCAGGAGACAGGGGTCCCTATGGCACTGACATCGGCCCAGGCGGA
GGCTATGGGGCAGCAGCAGAAGGCGGCATGTATGCTGGCAATGGCGGACTATTGGGAGCTGACTTTGCTGGAGATCTGGATTACAATGAG
CTGGCTGTGAGGGTGTCAGAGAGCATGCAGCGTCAGGGCCTACTGCAAGGGATGGCCTACACTGTCCAGGGCCCACCAGGCCAGCCTGGG
CCACAGGGGCCACCCGGCATCAGCAAGGTCTTCTCTGCCTACAGCAACGTGACTGCGGACCTCATGGACTTCTTCCAAACTTATGGAGCC
ATTCAAGGACCCCCTGGGCAAAAAGGAGAGATGGGCACTCCAGGACCCAAAGGTGACAGGGGCCCTGCTGGGCCACCAGGTCATCCTGGG
CCACCTGGCCCTCGAGGACACAAGGGAGAAAAAGGAGACAAAGGTGACCAAGTCTATGCTGGGCGGAGAAGGAGAAGAAGTATTGCTGTC
AAGCCGTGAGCTAGCCATGGCAGGACAGCTCCTGGACCAGGTCTCATAATGCATGTGGCACTTAGGTCCAAGGTCTCCAGAGGGTGAAAG
CTGGAGTCTGTCAATGTCCTACTGAGACAGCACAGCCAACCTAGCTAGCAACATTTGTTTTAGTCTGAACAATATATACTTATAGAATTC
AGTCAAAGATACACAATCTGAAACAGCTTCATGGGGTGGACTCTAACAGTAGTTGCAATGTTTTAGAATGAGACTTACTTCTCTGCTATC
TAGATCTGAACTCCTTGGCTTCTTTACTTAGTTCAAGCCCCAGCCTAGGAAAGCCAGTTACATAAAAGTTGGCTCAGGAGTCTTAGAGCT
TTACCTAAATATGAGCCCAGAAAACGGAGGATGGGGGTGGGGCGCCTTCCTGGAGGTGACACTTGATGGGGGTGTGTTCTGGTTACTGTT
CTAAGGCTGTGCCATCAGCTCCTTCCTCCCCTGTTCATTCTGCATTCTCTAGTCAGTTGGCTAAGAAGTGACTCTTGCAACTAAAAAAAT
TAAGAAATTCACTTCCCCTCTAGGAGGTGATGATAGGGTTTCTAATGGTTATATGTATATCACATTCCCATTTGCTTAGAAAGTCTGATT
GTAGCTATGATTGTCCGTAGGCCCATACTAGAGTTCATGGATATGTTATACTGAACCAGGCCAGAGCAAACAGAAAAAGAAGGTTGAGGG
CAATGGACAAGGAAGGAATAAAGGGAGAAGAGGGAAAACAGAAAACCTGATGCTGGGGACACAGCATCAGCTCAAGACGTCACCCTCCAT
TCTGCACTCAGAAAATGGCACTTGGGGGACTGGGCGCAGTTGGTCTTTAACCACTTTTCAATGTCTAAAAACATTTGTTTGTGGTCTATA

>61301_61301_4_OBFC1-COL17A1_OBFC1_chr10_105648830_ENST00000369764_COL17A1_chr10_105795321_ENST00000369733_length(amino acids)=638AA_BP=324
MMQPGSSRCEEETPSLLWGLDPVFLAFAKLYIRDILDMKESRQVPGVFLYNGHPIKQVDVLGTVIGVRERDAFYSYGVDDSTGVINCICW
KKLNTESVSAAPSAARELSLTSQLKKLQETIEQKTKIEIGDTIRVRGSIRTYREEREIHATTYYKVDDPVWNIQIARMLELPTIYRKVYD
QPFHSSALEKEEALSNPGALDLPSLTSLLSEKAKEFLMENRVQSFYQQELEMVESLLSLANQPVIHSASSDQVNFKKDTTSKAIHSIFKN
AIQLLQEKGLVFQKDDGFDNLYYVTREDKDLHRKIHRIIQQDCQKPNRSGISIGLPGPPGPPGLPGTSYEELLSLLRAAGLSFIPGPPGP
PGPPGPRGPPGVSGALATYAAENSDSFRSELISYLTSPDVRSFIVGPPGPPGPQGPPGDSRLLSTDASHSRGSSSSSHSSSVRRGSSYSS
SMSTGGGGAGSLGAGGAFGEAAGDRGPYGTDIGPGGGYGAAAEGGMYAGNGGLLGADFAGDLDYNELAVRVSESMQRQGLLQGMAYTVQG
PPGQPGPQGPPGISKVFSAYSNVTADLMDFFQTYGAIQGPPGQKGEMGTPGPKGDRGPAGPPGHPGPPGPRGHKGEKGDKGDQVYAGRRR

--------------------------------------------------------------

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Fusion Gene PPI Analysis for OBFC1-COL17A1


check button Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in

ChiPPI page.


check button Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160)
HgeneHgene's interactorsTgeneTgene's interactors


check button - Retained PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenStill interaction with
HgeneOBFC1chr10:105648829chr10:105795321ENST00000224950-9101_185316.3333333333333369.0CTC1
HgeneOBFC1chr10:105648829chr10:105795321ENST00000369764-891_185316.3333333333333369.0CTC1
HgeneOBFC1chr10:105648830chr10:105795321ENST00000224950-9101_185316.3333333333333369.0CTC1
HgeneOBFC1chr10:105648830chr10:105795321ENST00000369764-891_185316.3333333333333369.0CTC1


check button - Lost PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


check button - Retained PPIs, but lost function due to frame-shift fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


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Related Drugs for OBFC1-COL17A1


check button Drugs targeting genes involved in this fusion gene.
(DrugBank Version 5.1.8 2021-05-08)
PartnerGeneUniProtAccDrugBank IDDrug nameDrug activityDrug typeDrug status

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Related Diseases for OBFC1-COL17A1


check button Diseases associated with fusion partners.
(DisGeNet 4.0)
PartnerGeneDisease IDDisease name# pubmedsSource