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Center for Computational Systems Medicine
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Fusion Gene Summary

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Fusion Gene ORF analysis

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Fusion Genomic Features

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Fusion Protein Features

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Fusion Gene Sequence

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Fusion Gene PPI analysis

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Related Drugs

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Related Diseases

Fusion gene:ARHGAP5-KIAA0391 (FusionGDB2 ID:6139)

Fusion Gene Summary for ARHGAP5-KIAA0391

check button Fusion gene summary
Fusion gene informationFusion gene name: ARHGAP5-KIAA0391
Fusion gene ID: 6139
HgeneTgene
Gene symbol

ARHGAP5

KIAA0391

Gene ID

394

9692

Gene nameRho GTPase activating protein 5protein only RNase P catalytic subunit
SynonymsGFI2|RhoGAP5|p190-B|p190BRhoGAPKIAA0391|MRPP3
Cytomap

14q12

14q13.2

Type of geneprotein-codingprotein-coding
Descriptionrho GTPase-activating protein 5growth factor independent 2p100 RasGAP-associated p105 proteinp105 RhoGAPrho-type GTPase-activating protein 5mitochondrial ribonuclease P catalytic subunitmitochondrial RNase P protein 3mitochondrial RNase P subunit 3mitochondrial ribonuclease P protein 3proteinaceous RNase P
Modification date2020031320200313
UniProtAcc

Q13017

.
Ensembl transtripts involved in fusion geneENST00000345122, ENST00000432921, 
ENST00000433497, ENST00000539826, 
ENST00000556611, ENST00000396582, 
ENST00000603588, ENST00000250377, 
ENST00000321130, ENST00000534898, 
ENST00000604948, ENST00000605870, 
ENST00000557565, ENST00000603544, 
Fusion gene scores* DoF score10 X 4 X 7=28010 X 6 X 7=420
# samples 1214
** MAII scorelog2(12/280*10)=-1.22239242133645
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0		log2(14/420*10)=-1.58496250072116
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0
Context

PubMed: ARHGAP5 [Title/Abstract] AND KIAA0391 [Title/Abstract] AND fusion [Title/Abstract]

Most frequent breakpointARHGAP5(32586493)-KIAA0391(35742641), # samples:1
Anticipated loss of major functional domain due to fusion event.ARHGAP5-KIAA0391 seems lost the major protein functional domain in Hgene partner, which is a CGC due to the frame-shifted ORF.
ARHGAP5-KIAA0391 seems lost the major protein functional domain in Tgene partner, which is a essential gene due to the frame-shifted ORF.
* DoF score (Degree of Frequency) = # partners X # break points X # cancer types
** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)

check button Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez
PartnerGeneGO IDGO termPubMed ID
TgeneKIAA0391

GO:0097745

mitochondrial tRNA 5'-end processing

25953853


check buttonFusion gene breakpoints across ARHGAP5 (5'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check buttonFusion gene breakpoints across KIAA0391 (3'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check button Fusion gene information from two resources (ChiTars 5.0 and ChimerDB 4.0)
* All genome coordinats were lifted-over on hg19.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
SourceDiseaseSampleHgeneHchrHbpHstrandTgeneTchrTbpTstrand
ChimerDB4LUADTCGA-MP-A4T6-01AARHGAP5chr14

32586493

+KIAA0391chr14

35742641

+


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Fusion Gene ORF analysis for ARHGAP5-KIAA0391

check button Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
ORFHenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrand
5CDS-intronENST00000345122ENST00000603588ARHGAP5chr14

32586493

+KIAA0391chr14

35742641

+
5CDS-intronENST00000432921ENST00000603588ARHGAP5chr14

32586493

+KIAA0391chr14

35742641

+
5CDS-intronENST00000433497ENST00000603588ARHGAP5chr14

32586493

+KIAA0391chr14

35742641

+
5CDS-intronENST00000539826ENST00000603588ARHGAP5chr14

32586493

+KIAA0391chr14

35742641

+
5CDS-intronENST00000556611ENST00000603588ARHGAP5chr14

32586493

+KIAA0391chr14

35742641

+
Frame-shiftENST00000345122ENST00000250377ARHGAP5chr14

32586493

+KIAA0391chr14

35742641

+
Frame-shiftENST00000345122ENST00000321130ARHGAP5chr14

32586493

+KIAA0391chr14

35742641

+
Frame-shiftENST00000345122ENST00000534898ARHGAP5chr14

32586493

+KIAA0391chr14

35742641

+
Frame-shiftENST00000345122ENST00000604948ARHGAP5chr14

32586493

+KIAA0391chr14

35742641

+
Frame-shiftENST00000345122ENST00000605870ARHGAP5chr14

32586493

+KIAA0391chr14

35742641

+
Frame-shiftENST00000432921ENST00000250377ARHGAP5chr14

32586493

+KIAA0391chr14

35742641

+
Frame-shiftENST00000432921ENST00000321130ARHGAP5chr14

32586493

+KIAA0391chr14

35742641

+
Frame-shiftENST00000432921ENST00000534898ARHGAP5chr14

32586493

+KIAA0391chr14

35742641

+
Frame-shiftENST00000432921ENST00000604948ARHGAP5chr14

32586493

+KIAA0391chr14

35742641

+
Frame-shiftENST00000432921ENST00000605870ARHGAP5chr14

32586493

+KIAA0391chr14

35742641

+
Frame-shiftENST00000433497ENST00000250377ARHGAP5chr14

32586493

+KIAA0391chr14

35742641

+
Frame-shiftENST00000433497ENST00000321130ARHGAP5chr14

32586493

+KIAA0391chr14

35742641

+
Frame-shiftENST00000433497ENST00000534898ARHGAP5chr14

32586493

+KIAA0391chr14

35742641

+
Frame-shiftENST00000433497ENST00000604948ARHGAP5chr14

32586493

+KIAA0391chr14

35742641

+
Frame-shiftENST00000433497ENST00000605870ARHGAP5chr14

32586493

+KIAA0391chr14

35742641

+
Frame-shiftENST00000539826ENST00000250377ARHGAP5chr14

32586493

+KIAA0391chr14

35742641

+
Frame-shiftENST00000539826ENST00000321130ARHGAP5chr14

32586493

+KIAA0391chr14

35742641

+
Frame-shiftENST00000539826ENST00000534898ARHGAP5chr14

32586493

+KIAA0391chr14

35742641

+
Frame-shiftENST00000539826ENST00000604948ARHGAP5chr14

32586493

+KIAA0391chr14

35742641

+
Frame-shiftENST00000539826ENST00000605870ARHGAP5chr14

32586493

+KIAA0391chr14

35742641

+
Frame-shiftENST00000556611ENST00000250377ARHGAP5chr14

32586493

+KIAA0391chr14

35742641

+
Frame-shiftENST00000556611ENST00000321130ARHGAP5chr14

32586493

+KIAA0391chr14

35742641

+
Frame-shiftENST00000556611ENST00000534898ARHGAP5chr14

32586493

+KIAA0391chr14

35742641

+
Frame-shiftENST00000556611ENST00000604948ARHGAP5chr14

32586493

+KIAA0391chr14

35742641

+
Frame-shiftENST00000556611ENST00000605870ARHGAP5chr14

32586493

+KIAA0391chr14

35742641

+
In-frameENST00000345122ENST00000557565ARHGAP5chr14

32586493

+KIAA0391chr14

35742641

+
In-frameENST00000345122ENST00000603544ARHGAP5chr14

32586493

+KIAA0391chr14

35742641

+
In-frameENST00000432921ENST00000557565ARHGAP5chr14

32586493

+KIAA0391chr14

35742641

+
In-frameENST00000432921ENST00000603544ARHGAP5chr14

32586493

+KIAA0391chr14

35742641

+
In-frameENST00000433497ENST00000557565ARHGAP5chr14

32586493

+KIAA0391chr14

35742641

+
In-frameENST00000433497ENST00000603544ARHGAP5chr14

32586493

+KIAA0391chr14

35742641

+
In-frameENST00000539826ENST00000557565ARHGAP5chr14

32586493

+KIAA0391chr14

35742641

+
In-frameENST00000539826ENST00000603544ARHGAP5chr14

32586493

+KIAA0391chr14

35742641

+
In-frameENST00000556611ENST00000557565ARHGAP5chr14

32586493

+KIAA0391chr14

35742641

+
In-frameENST00000556611ENST00000603544ARHGAP5chr14

32586493

+KIAA0391chr14

35742641

+
intron-3CDSENST00000396582ENST00000250377ARHGAP5chr14

32586493

+KIAA0391chr14

35742641

+
intron-3CDSENST00000396582ENST00000321130ARHGAP5chr14

32586493

+KIAA0391chr14

35742641

+
intron-3CDSENST00000396582ENST00000534898ARHGAP5chr14

32586493

+KIAA0391chr14

35742641

+
intron-3CDSENST00000396582ENST00000557565ARHGAP5chr14

32586493

+KIAA0391chr14

35742641

+
intron-3CDSENST00000396582ENST00000603544ARHGAP5chr14

32586493

+KIAA0391chr14

35742641

+
intron-3CDSENST00000396582ENST00000604948ARHGAP5chr14

32586493

+KIAA0391chr14

35742641

+
intron-3CDSENST00000396582ENST00000605870ARHGAP5chr14

32586493

+KIAA0391chr14

35742641

+
intron-intronENST00000396582ENST00000603588ARHGAP5chr14

32586493

+KIAA0391chr14

35742641

+

check buttonORFfinder result based on the fusion transcript sequence of in-frame fusion genes.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandSeq length
(transcript)		BP loci
(transcript)		Predicted start
(transcript)		Predicted stop
(transcript)		Seq length
(amino acids)
ENST00000556611ARHGAP5chr1432586493+ENST00000557565KIAA0391chr1435742641+5973411725541331292
ENST00000556611ARHGAP5chr1432586493+ENST00000603544KIAA0391chr1435742641+4353411725541331292
ENST00000539826ARHGAP5chr1432586493+ENST00000557565KIAA0391chr1435742641+5958410223741181293
ENST00000539826ARHGAP5chr1432586493+ENST00000603544KIAA0391chr1435742641+4338410223741181293
ENST00000432921ARHGAP5chr1432586493+ENST00000557565KIAA0391chr1435742641+6033417731541931292
ENST00000432921ARHGAP5chr1432586493+ENST00000603544KIAA0391chr1435742641+4413417731541931292
ENST00000345122ARHGAP5chr1432586493+ENST00000557565KIAA0391chr1435742641+6036418031541961293
ENST00000345122ARHGAP5chr1432586493+ENST00000603544KIAA0391chr1435742641+4416418031541961293
ENST00000433497ARHGAP5chr1432586493+ENST00000557565KIAA0391chr1435742641+212827212641959231
ENST00000433497ARHGAP5chr1432586493+ENST00000603544KIAA0391chr1435742641+50827218540372

check buttonDeepORF prediction of the coding potential based on the fusion transcript sequence of in-frame fusion genes. DeepORF is a coding potential classifier based on convolutional neural network by comparing the real Ribo-seq data. If the no-coding score < 0.5 and coding score > 0.5, then the in-frame fusion transcript is predicted as being likely translated.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandNo-coding scoreCoding score
ENST00000556611ENST00000557565ARHGAP5chr1432586493+KIAA0391chr1435742641+0.0003086110.99969137
ENST00000556611ENST00000603544ARHGAP5chr1432586493+KIAA0391chr1435742641+0.0003297730.99967027
ENST00000539826ENST00000557565ARHGAP5chr1432586493+KIAA0391chr1435742641+0.0007441520.99925584
ENST00000539826ENST00000603544ARHGAP5chr1432586493+KIAA0391chr1435742641+0.000793170.99920684
ENST00000432921ENST00000557565ARHGAP5chr1432586493+KIAA0391chr1435742641+0.0003313160.9996687
ENST00000432921ENST00000603544ARHGAP5chr1432586493+KIAA0391chr1435742641+0.0003529380.999647
ENST00000345122ENST00000557565ARHGAP5chr1432586493+KIAA0391chr1435742641+0.0008133690.9991866
ENST00000345122ENST00000603544ARHGAP5chr1432586493+KIAA0391chr1435742641+0.0008686990.99913126
ENST00000433497ENST00000557565ARHGAP5chr1432586493+KIAA0391chr1435742641+0.00154220.9984578
ENST00000433497ENST00000603544ARHGAP5chr1432586493+KIAA0391chr1435742641+0.478300630.5216993

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Fusion Genomic Features for ARHGAP5-KIAA0391


check buttonFusionAI prediction of the potential fusion gene breakpoint based on the pre-mature RNA sequence context (+/- 5kb of individual partner genes, total 20kb length sequence). FusionAI is a fusion gene breakpoint classifier based on convolutional neural network by comparing the fusion positive and negative sequence context of ~ 20K fusion gene data. From here, we can have the relative potentency of the 20K genomic sequence how individual sequnce will be likely used as the gene fusion breakpoints.
HgeneHchrHbpHstrandTgeneTchrTbpTstrand1-pp (fusion gene breakpoint)
ARHGAP5chr1432586493+KIAA0391chr1435742640+1.44E-070.9999999
ARHGAP5chr1432586493+KIAA0391chr1435742640+1.44E-070.9999999

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions. We integrated a total of 44 different types of human genomic feature loci information across five big categories including virus integration sites, repeats, structural variants, chromatin states, and gene expression regulation. More details are in help page.
genomic feature

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions that are ovelapped with the top 1% feature importance score regions. More details are in help page.
genomic feature of top 1%

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Fusion Protein Features for ARHGAP5-KIAA0391


check button Four levels of functional features of fusion genes
Go to FGviewer search page for the most frequent breakpoint (https://ccsmweb.uth.edu/FGviewer/chr14:32586493/chr14:35742641)
- FGviewer provides the online visualization of the retention search of the protein functional features across DNA, RNA, protein, and pathological levels.
- How to search
1. Put your fusion gene symbol.
2. Press the tab key until there will be shown the breakpoint information filled.
4. Go down and press 'Search' tab twice.
4. Go down to have the hyperlink of the search result.
5. Click the hyperlink.
6. See the FGviewer result for your fusion gene.
FGviewer

check buttonMain function of each fusion partner protein. (from UniProt)
HgeneTgene
ARHGAP5

Q13017

.
FUNCTION: GTPase-activating protein for Rho family members (PubMed:8537347). {ECO:0000269|PubMed:8537347}.FUNCTION: Transcriptional activator which is required for calcium-dependent dendritic growth and branching in cortical neurons. Recruits CREB-binding protein (CREBBP) to nuclear bodies. Component of the CREST-BRG1 complex, a multiprotein complex that regulates promoter activation by orchestrating a calcium-dependent release of a repressor complex and a recruitment of an activator complex. In resting neurons, transcription of the c-FOS promoter is inhibited by BRG1-dependent recruitment of a phospho-RB1-HDAC1 repressor complex. Upon calcium influx, RB1 is dephosphorylated by calcineurin, which leads to release of the repressor complex. At the same time, there is increased recruitment of CREBBP to the promoter by a CREST-dependent mechanism, which leads to transcriptional activation. The CREST-BRG1 complex also binds to the NR2B promoter, and activity-dependent induction of NR2B expression involves a release of HDAC1 and recruitment of CREBBP (By similarity). {ECO:0000250}.

check buttonRetention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at

download page


* Minus value of BPloci means that the break pointn is located before the CDS.
- In-frame and retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneARHGAP5chr14:32586493chr14:35742641ENST00000345122+371225_124512881503.0Compositional biasNote=Lys-rich
HgeneARHGAP5chr14:32586493chr14:35742641ENST00000432921+371225_124512871502.0Compositional biasNote=Lys-rich
HgeneARHGAP5chr14:32586493chr14:35742641ENST00000539826+371225_124512881503.0Compositional biasNote=Lys-rich
HgeneARHGAP5chr14:32586493chr14:35742641ENST00000556611+371225_124512871502.0Compositional biasNote=Lys-rich
HgeneARHGAP5chr14:32586493chr14:35742641ENST00000345122+37267_32512881503.0DomainNote=FF 1
HgeneARHGAP5chr14:32586493chr14:35742641ENST00000345122+37366_42012881503.0DomainNote=FF 2
HgeneARHGAP5chr14:32586493chr14:35742641ENST00000345122+37427_48112881503.0DomainNote=FF 3
HgeneARHGAP5chr14:32586493chr14:35742641ENST00000345122+37482_54812881503.0DomainNote=FF 4
HgeneARHGAP5chr14:32586493chr14:35742641ENST00000345122+37590_76312881503.0DomainpG1 pseudoGTPase
HgeneARHGAP5chr14:32586493chr14:35742641ENST00000345122+37779_94412881503.0DomainpG2 pseudoGTPase
HgeneARHGAP5chr14:32586493chr14:35742641ENST00000432921+37267_32512871502.0DomainNote=FF 1
HgeneARHGAP5chr14:32586493chr14:35742641ENST00000432921+37366_42012871502.0DomainNote=FF 2
HgeneARHGAP5chr14:32586493chr14:35742641ENST00000432921+37427_48112871502.0DomainNote=FF 3
HgeneARHGAP5chr14:32586493chr14:35742641ENST00000432921+37482_54812871502.0DomainNote=FF 4
HgeneARHGAP5chr14:32586493chr14:35742641ENST00000432921+37590_76312871502.0DomainpG1 pseudoGTPase
HgeneARHGAP5chr14:32586493chr14:35742641ENST00000432921+37779_94412871502.0DomainpG2 pseudoGTPase
HgeneARHGAP5chr14:32586493chr14:35742641ENST00000539826+37267_32512881503.0DomainNote=FF 1
HgeneARHGAP5chr14:32586493chr14:35742641ENST00000539826+37366_42012881503.0DomainNote=FF 2
HgeneARHGAP5chr14:32586493chr14:35742641ENST00000539826+37427_48112881503.0DomainNote=FF 3
HgeneARHGAP5chr14:32586493chr14:35742641ENST00000539826+37482_54812881503.0DomainNote=FF 4
HgeneARHGAP5chr14:32586493chr14:35742641ENST00000539826+37590_76312881503.0DomainpG1 pseudoGTPase
HgeneARHGAP5chr14:32586493chr14:35742641ENST00000539826+37779_94412881503.0DomainpG2 pseudoGTPase
HgeneARHGAP5chr14:32586493chr14:35742641ENST00000556611+37267_32512871502.0DomainNote=FF 1
HgeneARHGAP5chr14:32586493chr14:35742641ENST00000556611+37366_42012871502.0DomainNote=FF 2
HgeneARHGAP5chr14:32586493chr14:35742641ENST00000556611+37427_48112871502.0DomainNote=FF 3
HgeneARHGAP5chr14:32586493chr14:35742641ENST00000556611+37482_54812871502.0DomainNote=FF 4
HgeneARHGAP5chr14:32586493chr14:35742641ENST00000556611+37590_76312871502.0DomainpG1 pseudoGTPase
HgeneARHGAP5chr14:32586493chr14:35742641ENST00000556611+37779_94412871502.0DomainpG2 pseudoGTPase
TgeneKIAA0391chr14:32586493chr14:35742641ENST0000060587057342_578168212.0DomainNote=PRORP

- In-frame and not-retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneARHGAP5chr14:32586493chr14:35742641ENST00000396582+151225_12450238.0Compositional biasNote=Lys-rich
HgeneARHGAP5chr14:32586493chr14:35742641ENST00000433497+261225_124527242.0Compositional biasNote=Lys-rich
HgeneARHGAP5chr14:32586493chr14:35742641ENST00000345122+371262_144912881503.0DomainRho-GAP
HgeneARHGAP5chr14:32586493chr14:35742641ENST00000396582+151262_14490238.0DomainRho-GAP
HgeneARHGAP5chr14:32586493chr14:35742641ENST00000396582+15267_3250238.0DomainNote=FF 1
HgeneARHGAP5chr14:32586493chr14:35742641ENST00000396582+15366_4200238.0DomainNote=FF 2
HgeneARHGAP5chr14:32586493chr14:35742641ENST00000396582+15427_4810238.0DomainNote=FF 3
HgeneARHGAP5chr14:32586493chr14:35742641ENST00000396582+15482_5480238.0DomainNote=FF 4
HgeneARHGAP5chr14:32586493chr14:35742641ENST00000396582+15590_7630238.0DomainpG1 pseudoGTPase
HgeneARHGAP5chr14:32586493chr14:35742641ENST00000396582+15779_9440238.0DomainpG2 pseudoGTPase
HgeneARHGAP5chr14:32586493chr14:35742641ENST00000432921+371262_144912871502.0DomainRho-GAP
HgeneARHGAP5chr14:32586493chr14:35742641ENST00000433497+261262_144927242.0DomainRho-GAP
HgeneARHGAP5chr14:32586493chr14:35742641ENST00000433497+26267_32527242.0DomainNote=FF 1
HgeneARHGAP5chr14:32586493chr14:35742641ENST00000433497+26366_42027242.0DomainNote=FF 2
HgeneARHGAP5chr14:32586493chr14:35742641ENST00000433497+26427_48127242.0DomainNote=FF 3
HgeneARHGAP5chr14:32586493chr14:35742641ENST00000433497+26482_54827242.0DomainNote=FF 4
HgeneARHGAP5chr14:32586493chr14:35742641ENST00000433497+26590_76327242.0DomainpG1 pseudoGTPase
HgeneARHGAP5chr14:32586493chr14:35742641ENST00000433497+26779_94427242.0DomainpG2 pseudoGTPase
HgeneARHGAP5chr14:32586493chr14:35742641ENST00000539826+371262_144912881503.0DomainRho-GAP
HgeneARHGAP5chr14:32586493chr14:35742641ENST00000556611+371262_144912871502.0DomainRho-GAP
TgeneKIAA0391chr14:32586493chr14:35742641ENST0000025037768342_578445489.0DomainNote=PRORP
TgeneKIAA0391chr14:32586493chr14:35742641ENST0000032113057342_578524568.0DomainNote=PRORP
TgeneKIAA0391chr14:32586493chr14:35742641ENST0000053489868342_578540584.0DomainNote=PRORP
TgeneKIAA0391chr14:32586493chr14:35742641ENST0000060354457342_578524568.0DomainNote=PRORP
TgeneKIAA0391chr14:32586493chr14:35742641ENST0000060494868342_578445489.0DomainNote=PRORP


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Fusion Gene Sequence for ARHGAP5-KIAA0391


check button For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. To have fusion amino acid sequence, we ran ORFfinder and chose the longest ORF among the all predicted ones.
>6139_6139_1_ARHGAP5-KIAA0391_ARHGAP5_chr14_32586493_ENST00000345122_KIAA0391_chr14_35742641_ENST00000557565_length(transcript)=6036nt_BP=4180nt
CTCGGTGAGCGCGCCGAGGAAGAGAGGCGAGCGGAGAGTGGAGGAGGAGGCGGCGGCGGCGGGAGCGGTCCCCAGGAATGTCGCTGCCGC
CGCCACCGCCGGGGCCGCTGCCGTTGAGGAGGAGACGGAGGAGACCGACGTTGTTAGGAAGATGATCCCTATGATCTTGAAGATGTTTCT
GCACAGAAATGAGGGAAATACAAAGAACCAAATACAGTTCTGAAATTTGGGATCTGTATTTTGAGATGATTTTATTTTCAGAATGAGAAG
CATATCTGGTTACCTTTATGAATGTAGAGACATGAGAAGAGAGTTATGATGGCAAAAAACAAAGAGCCTCGTCCCCCATCCTATACCATC
AGTATAGTTGGACTCTCTGGGACTGAAAAAGACAAAGGTAACTGTGGAGTTGGAAAGTCTTGTTTGTGCAATAGATTTGTACGCTCAAAA
GCAGATGAATATTATCCAGAGCATACTTCTGTGCTTAGCACCATTGACTTTGGAGGACGAGTAGTAAACAATGATCACTTTTTGTACTGG
GGTGACATAATACAAAATAGTGAAGATGGAGTAGAATGCAAAATTCATGTCATTGAACAAACAGAGTTCATTGATGACCAGACTTTCTTG
CCTCATCGGAGTACGAATTTGCAACCATATATAAAACGTGCAGCTGCATCTAAATTGCAGTCAGCAGAAAAACTAATGTACATTTGCACT
GATCAGCTAGGCTTAGAACAAGACTTTGAACAGAAGCAAATGCCTGAAGGGAAGCTCAACGTAGATGGATTTTTATTATGCATTGATGTA
AGTCAAGGATGCAATAGGAAGTTTGATGATCAACTTAAATTTGTGAATAACCTTTTTGTCCAGTTATCAAAATCAAAAAAACCTGTAATA
ATAGCAGCAACTAAATGTGATGAATGCGTGGATCATTATCTTAGAGAAGTTCAGGCATTTGCTTCAAATAAAAAGAACCTTCTTGTAGTG
GAAACATCAGCACGATTTAATGTCAACATTGAAACATGTTTTACTGCACTGGTACAAATGTTGGATAAAACTCGTAGCAAGCCTAAAATT
ATTCCCTATTTGGATGCTTATAAAACACAGAGACAACTTGTTGTCACAGCAACAGATAAGTTTGAAAAACTTGTGCAGACTGTGAGAGAT
TATCATGCAACTTGGAAAACTGTTAGTAATAAATTAAAAAATCATCCTGATTATGAAGAATACATCAACTTAGAGGGAACAAGAAAGGCC
AGAAATACATTCTCAAAACATATAGAACAACTTAAACAGGAACATATAAGAAAAAGGAGAGAAGAGTATATAAATACTTTACCAAGAGCT
TTTAACACTCTTTTGCCAAATCTAGAAGAGATTGAACATTTGAATTGGTCAGAAGCTTTGAAGTTAATGGAAAAGAGAGCAGATTTCCAG
TTATGTTTTGTGGTGCTAGAAAAAACTCCTTGGGATGAAACTGACCATATAGACAAAATTAATGATAGGCGGATTCCATTTGACCTCCTG
AGCACTTTAGAAGCTGAAAAAGTCTATCAGAACCATGTACAGCATCTGATATCCGAGAAGAGGAGGGTGGAAATGAAGGAAAAATTCAAA
AAGACTTTGGAAAAAATTCAATTCATTTCACCAGGGCAGCCATGGGAGGAAGTTATGTGCTTTGTTATGGAGGATGAAGCCTACAAATAT
ATCACTGAGGCTGATAGCAAAGAGGTATATGGTAGGCATCAGCGAGAAATAGTTGAAAAAGCCAAAGAAGAGTTTCAAGAAATGCTTTTT
GAGCATTCTGAACTTTTTTATGATTTAGATCTTAATGCAACACCTAGTTCAGATAAAATGAGTGAAATTCATACAGTTCTGAGTGAAGAA
CCTAGATATAAAGCTTTACAGAAACTTGCACCTGATAGGGAATCCCTTCTACTTAAGCATATAGGATTTGTTTATCATCCCACTAAAGAA
ACATGTCTTAGTGGCCAAAATTGTACAGACATTAAAGTGGAGCAGTTACTTGCTAGTAGTCTTTTACAGTTGGATCATGGCCGCTTAAGA
TTATATCACGATAGTACCAATATAGATAAAGTTAACCTTTTTATTTTAGGGAAGGATGGCCTTGCCCAAGAACTAGCAAATGAGATAAGG
ACACAATCCACTGATGATGAGTATGCCTTAGATGGAAAAATTTATGAACTTGATCTTCGGCCGGTTGATGCCAAATCGCCTTACTTTTTG
AGTCAGTTATGGACTGCCGCCTTTAAACCACATGGGTGCTTCTGTGTATTTAATTCCATTGAGTCATTGAGTTTTATTGGGGAATTTATT
GGGAAAATAAGAACTGAAGCTTCTCAGATCAGAAAAGATAAATACATGGCTAATCTTCCATTTACATTAATTCTGGCTAATCAGAGAGAT
TCCATTAGTAAGAATCTACCAATTCTCAGGCACCAAGGGCAGCAGTTGGCAAACAAGTTGCAATGTCCTTTTGTAGATGTACCTGCTGGT
ACATATCCTCGTAAATTTAATGAAACCCAAATAAAGCAAGCTCTCAGAGGAGTATTGGAATCAGTTAAACACAATTTGGATGTGGTGAGC
CCAATTCCTGCCAATAAGGACTTATCAGAAGCTGACTTGAGAATTGTCATGTGCGCCATGTGTGGAGATCCATTTAGTGTGGATCTTATT
CTTTCACCCTTCCTTGATTCTCATTCTTGCAGTGCTGCTCAAGCTGGACAGAATAATTCCCTAATGCTTGATAAAATCATTGGTGAAAAA
AGGAGGCGAATACAGATCACAATATTATCATACCACTCTTCAATTGGAGTAAGAAAAGATGAACTAGTTCATGGGTATATATTAGTTTAC
TCTGCAAAACGGAAAGCTTCGATGGGAATGCTTCGAGCATTTCTATCAGAAGTTCAAGACACCATTCCTGTACAGCTGGTGGCAGTTACT
GACAGCCAAGCAGATTTTTTTGAAAATGAGGCTATCAAAGAGTTAATGACTGAAGGAGAACACATTGCAACTGAGATCACTGCTAAATTT
ACAGCACTGTATTCTTTATCTCAGTATCATCGGCAAACTGAGGTCTTTACTCTGTTTTTTAGTGATGTTCTAGAGAAAAAAAATATGATA
GAAAATTCTTATTTGTCTGATAATACAAGGGAATCAACCCATCAAAGTGAAGATGTTTTTCTACCATCTCCCAGAGACTGTTTTCCCTAT
AATAACTACCCTGATTCAGATGATGACACAGAAGCACCACCTCCTTATAGTCCAATTGGGGATGATGTACAGTTGCTTCCAACACCTAGT
GACCGTTCCAGATATAGATTAGATTTGGAAGGAAATGAGTATCCTATTCATAGTACCCCAAACTGTCATGACCATGAACGCAACCATAAA
GTGCCTCCACCTATTAAACCTAAACCAGTTGTACCTAAGACAAATGTGAAAAAACTCGATCCAAACCTTTTAAAAACAATTGAAGCTGGT
ATTGGTAAAAATCCAAGAAAGCAGACTTCCCGGGTGCCTTTGGCACATCCTGAAGATATGGATCCTTCAGATAACTATGCGGAACCCATT
GATACAATTTTCAAACAGAAGGGCTATTCTGATGAGATTTATGTTGTCCCAGATGATAGTCAAAATCGTATTAAAATTCGAAACTCATTT
GTAAATAACACCCAAGGAGATGAAGAAAATGGGTTTTCTGATAGAACCTCAAAAAGTCATGGGGAACGGAGGCCTTCAAAATACAAATAT
AAATCTAAAACCTTGTTTAGTAAAGCCAAGTCATACTATAGAAGAACACATTCAGATGCCAGTGATGATGAGGCTTTCACCACTTCTAAA
ACAAAAAGAAAAGGAAGACATCGTGGAAGTGAAGAAGATCCACTTCTTTCTCCTGTTGAAACTTGGAAAGGTGGTATTGATAATCCTGCA
ATCACTTCTGACCAGGAGTTAGATGATAAGAAGATGAAGAAGAAAACCCACAAAGTGAAAGAAGATAAAAAGCAGAAAAAGAAAACTAAG
AACTTCAATCCACCAACACGTAGAAATTGGGAAAGTAATTACTTTGGGATGCCCCTCCAGGATCTGGTTACAGCTGAGAAGCCCATACCA
CTATTTGTTGAGAAATGTGTGGAATTTATTGAAGATACAGCGTATTCTCAGCTATGACACAGTGGTGCAAACAACTGGAGACTCGTGGCA
CATACCATATGATGAAGACTTGGTAGAAAGATGTTCCTGTGAAGTACCAACCAAATGGCTTTGCCTCCACCAAAAGACATAGAGATTCTT
ACCTCTATGCTAAGTTTGTGTTTGGGTACCCTCTAGGTTGGCATCAGAGGCTCTTGAGCTGGTGTTTGTTTAGGGCATTGCCTCTGTCCT
GAAGATAAAAGGATTCTATTAACAGCATTGACATTGATTTTTTAATGAAATGAGATATATCTTTTCATAACCAGCTGCGTTTTTTTCCCC
TAACATTTGTTTTTGGAGGCTTATCAAGAGTTGGAGAACTTAGTGTAGAGCAAAACCTGCATTTCTCCTACTGGGCCAGCTATTCCACTT
AGCTTGGGTGACTAATAGTGCTTTTGGTATCCATTTTTTGCTACTTCTGACCTTGCCTTCCAGGCCTACCAATAGCAGAATCAATCCATC
TGTCCCTGAGATACTCATGTTGTTTCAAATGCCTCCTCCCATTTCTGGCATAGTCTCATTCTCTGTATGTTATGCCCTATCCACATGGAA
TCATTTATCGTCCTCTGTAATAAACTGGCCAAGATACTAAAGGCTTACTATTCATAGCAGTTTTTAATTACTTATCATCCAATTATTTGG
ATTGGAGAAGAGGGGGCATTCACTCCTCTTTTTCTTATTTTTTTTGGAAATAGAGTCTCAACTTACTCTGTCGCCAGGGCTGGAGTGCAG
TGACGTGATCACAGTTCACTGCAGCCTCAAACTCCCAGGCTCAAGCAATCTTCCTACCTCAGCCCTCCTGAGTAATTGGGACTACAGAAC
AGAGAATGTCAGTATCCAATAGGATGCCAGTGGAATTCCCTGACGATTCCATCCATGCGGCTCTGCTGGAGCAGGGTAGTGTCCTAGGCT
GGGAGAATGGGATGGAGCCTCCACCTCATGAAGTAGCTTCCTTTGGAGGTGGCTATGGCAGGTCTTCGGAGAGAATATGCTTTTAAGGCT
ATTAACCAGGGTGGCCTTACATCAGTAGCTGTCAGAGGGAAAGACTGTGCAGTAATTGTCACACAGAAGAAAGTACCTGACAAATTATTG
GATTCCAGCACAGTGACTCACTTATTCAAGATAACTGAAAACATTGGTTGTGTGATGACCGGAATGACAGCTGACAGCAGATCCCAGGTA
CAGAGGGCACGCTATGAGGCAGCTAACTGGAAATACAAGTATGGCTATGAGATTCCTGTGGACATGCTGTGTAAAAGAATTGCCGATATT
TCTCAGGTCTACACACAGAATGCTGAAATGAGGCCTCTTGGTTGTTGTATGATTTTAATTGGTATAGATGAAGAGCAAGGCCCTCAGGTA
TATAAGTGTGATCCTGCAGGTTACTACTGTGGGTTTAAAGCCACTGCAGCGGGAGTTAAACAAACTGAGTCAACCAGCTTCCTTGAAAAA
AAAGTGAAGAAGAAATTTGATTGGACATTTGAACAGACAGTGGAAACTGCAATTACATGCCTGTCTACTGTTCTATCAATTGATTTCAAA
CCTTCAGAAATAGAAGTTGGAGTAGTGACAGTTGAAAATCCTAAATTCAGGATTCTTACAGAAGCAGAGATTGATGCTCACCTTGTTGCT
CTAGCAGAGAGAGACTAAACATTGTCGTTAGTTTACCAGATCCGTGATGCCACTTACCTGTGTGTTTGGTAACAACAAACCAACATCATG
GAGGTCCCTGGATTGAAAAAGGAGCCTCTCCCACTCCTCCTACCACCGAAGTGGTTAGGACTCTATATAAATAAAAACAAGGCTTTTGGA

>6139_6139_1_ARHGAP5-KIAA0391_ARHGAP5_chr14_32586493_ENST00000345122_KIAA0391_chr14_35742641_ENST00000557565_length(amino acids)=1293AA_BP=
MMAKNKEPRPPSYTISIVGLSGTEKDKGNCGVGKSCLCNRFVRSKADEYYPEHTSVLSTIDFGGRVVNNDHFLYWGDIIQNSEDGVECKI
HVIEQTEFIDDQTFLPHRSTNLQPYIKRAAASKLQSAEKLMYICTDQLGLEQDFEQKQMPEGKLNVDGFLLCIDVSQGCNRKFDDQLKFV
NNLFVQLSKSKKPVIIAATKCDECVDHYLREVQAFASNKKNLLVVETSARFNVNIETCFTALVQMLDKTRSKPKIIPYLDAYKTQRQLVV
TATDKFEKLVQTVRDYHATWKTVSNKLKNHPDYEEYINLEGTRKARNTFSKHIEQLKQEHIRKRREEYINTLPRAFNTLLPNLEEIEHLN
WSEALKLMEKRADFQLCFVVLEKTPWDETDHIDKINDRRIPFDLLSTLEAEKVYQNHVQHLISEKRRVEMKEKFKKTLEKIQFISPGQPW
EEVMCFVMEDEAYKYITEADSKEVYGRHQREIVEKAKEEFQEMLFEHSELFYDLDLNATPSSDKMSEIHTVLSEEPRYKALQKLAPDRES
LLLKHIGFVYHPTKETCLSGQNCTDIKVEQLLASSLLQLDHGRLRLYHDSTNIDKVNLFILGKDGLAQELANEIRTQSTDDEYALDGKIY
ELDLRPVDAKSPYFLSQLWTAAFKPHGCFCVFNSIESLSFIGEFIGKIRTEASQIRKDKYMANLPFTLILANQRDSISKNLPILRHQGQQ
LANKLQCPFVDVPAGTYPRKFNETQIKQALRGVLESVKHNLDVVSPIPANKDLSEADLRIVMCAMCGDPFSVDLILSPFLDSHSCSAAQA
GQNNSLMLDKIIGEKRRRIQITILSYHSSIGVRKDELVHGYILVYSAKRKASMGMLRAFLSEVQDTIPVQLVAVTDSQADFFENEAIKEL
MTEGEHIATEITAKFTALYSLSQYHRQTEVFTLFFSDVLEKKNMIENSYLSDNTRESTHQSEDVFLPSPRDCFPYNNYPDSDDDTEAPPP
YSPIGDDVQLLPTPSDRSRYRLDLEGNEYPIHSTPNCHDHERNHKVPPPIKPKPVVPKTNVKKLDPNLLKTIEAGIGKNPRKQTSRVPLA
HPEDMDPSDNYAEPIDTIFKQKGYSDEIYVVPDDSQNRIKIRNSFVNNTQGDEENGFSDRTSKSHGERRPSKYKYKSKTLFSKAKSYYRR
THSDASDDEAFTTSKTKRKGRHRGSEEDPLLSPVETWKGGIDNPAITSDQELDDKKMKKKTHKVKEDKKQKKKTKNFNPPTRRNWESNYF

--------------------------------------------------------------
>6139_6139_2_ARHGAP5-KIAA0391_ARHGAP5_chr14_32586493_ENST00000345122_KIAA0391_chr14_35742641_ENST00000603544_length(transcript)=4416nt_BP=4180nt
CTCGGTGAGCGCGCCGAGGAAGAGAGGCGAGCGGAGAGTGGAGGAGGAGGCGGCGGCGGCGGGAGCGGTCCCCAGGAATGTCGCTGCCGC
CGCCACCGCCGGGGCCGCTGCCGTTGAGGAGGAGACGGAGGAGACCGACGTTGTTAGGAAGATGATCCCTATGATCTTGAAGATGTTTCT
GCACAGAAATGAGGGAAATACAAAGAACCAAATACAGTTCTGAAATTTGGGATCTGTATTTTGAGATGATTTTATTTTCAGAATGAGAAG
CATATCTGGTTACCTTTATGAATGTAGAGACATGAGAAGAGAGTTATGATGGCAAAAAACAAAGAGCCTCGTCCCCCATCCTATACCATC
AGTATAGTTGGACTCTCTGGGACTGAAAAAGACAAAGGTAACTGTGGAGTTGGAAAGTCTTGTTTGTGCAATAGATTTGTACGCTCAAAA
GCAGATGAATATTATCCAGAGCATACTTCTGTGCTTAGCACCATTGACTTTGGAGGACGAGTAGTAAACAATGATCACTTTTTGTACTGG
GGTGACATAATACAAAATAGTGAAGATGGAGTAGAATGCAAAATTCATGTCATTGAACAAACAGAGTTCATTGATGACCAGACTTTCTTG
CCTCATCGGAGTACGAATTTGCAACCATATATAAAACGTGCAGCTGCATCTAAATTGCAGTCAGCAGAAAAACTAATGTACATTTGCACT
GATCAGCTAGGCTTAGAACAAGACTTTGAACAGAAGCAAATGCCTGAAGGGAAGCTCAACGTAGATGGATTTTTATTATGCATTGATGTA
AGTCAAGGATGCAATAGGAAGTTTGATGATCAACTTAAATTTGTGAATAACCTTTTTGTCCAGTTATCAAAATCAAAAAAACCTGTAATA
ATAGCAGCAACTAAATGTGATGAATGCGTGGATCATTATCTTAGAGAAGTTCAGGCATTTGCTTCAAATAAAAAGAACCTTCTTGTAGTG
GAAACATCAGCACGATTTAATGTCAACATTGAAACATGTTTTACTGCACTGGTACAAATGTTGGATAAAACTCGTAGCAAGCCTAAAATT
ATTCCCTATTTGGATGCTTATAAAACACAGAGACAACTTGTTGTCACAGCAACAGATAAGTTTGAAAAACTTGTGCAGACTGTGAGAGAT
TATCATGCAACTTGGAAAACTGTTAGTAATAAATTAAAAAATCATCCTGATTATGAAGAATACATCAACTTAGAGGGAACAAGAAAGGCC
AGAAATACATTCTCAAAACATATAGAACAACTTAAACAGGAACATATAAGAAAAAGGAGAGAAGAGTATATAAATACTTTACCAAGAGCT
TTTAACACTCTTTTGCCAAATCTAGAAGAGATTGAACATTTGAATTGGTCAGAAGCTTTGAAGTTAATGGAAAAGAGAGCAGATTTCCAG
TTATGTTTTGTGGTGCTAGAAAAAACTCCTTGGGATGAAACTGACCATATAGACAAAATTAATGATAGGCGGATTCCATTTGACCTCCTG
AGCACTTTAGAAGCTGAAAAAGTCTATCAGAACCATGTACAGCATCTGATATCCGAGAAGAGGAGGGTGGAAATGAAGGAAAAATTCAAA
AAGACTTTGGAAAAAATTCAATTCATTTCACCAGGGCAGCCATGGGAGGAAGTTATGTGCTTTGTTATGGAGGATGAAGCCTACAAATAT
ATCACTGAGGCTGATAGCAAAGAGGTATATGGTAGGCATCAGCGAGAAATAGTTGAAAAAGCCAAAGAAGAGTTTCAAGAAATGCTTTTT
GAGCATTCTGAACTTTTTTATGATTTAGATCTTAATGCAACACCTAGTTCAGATAAAATGAGTGAAATTCATACAGTTCTGAGTGAAGAA
CCTAGATATAAAGCTTTACAGAAACTTGCACCTGATAGGGAATCCCTTCTACTTAAGCATATAGGATTTGTTTATCATCCCACTAAAGAA
ACATGTCTTAGTGGCCAAAATTGTACAGACATTAAAGTGGAGCAGTTACTTGCTAGTAGTCTTTTACAGTTGGATCATGGCCGCTTAAGA
TTATATCACGATAGTACCAATATAGATAAAGTTAACCTTTTTATTTTAGGGAAGGATGGCCTTGCCCAAGAACTAGCAAATGAGATAAGG
ACACAATCCACTGATGATGAGTATGCCTTAGATGGAAAAATTTATGAACTTGATCTTCGGCCGGTTGATGCCAAATCGCCTTACTTTTTG
AGTCAGTTATGGACTGCCGCCTTTAAACCACATGGGTGCTTCTGTGTATTTAATTCCATTGAGTCATTGAGTTTTATTGGGGAATTTATT
GGGAAAATAAGAACTGAAGCTTCTCAGATCAGAAAAGATAAATACATGGCTAATCTTCCATTTACATTAATTCTGGCTAATCAGAGAGAT
TCCATTAGTAAGAATCTACCAATTCTCAGGCACCAAGGGCAGCAGTTGGCAAACAAGTTGCAATGTCCTTTTGTAGATGTACCTGCTGGT
ACATATCCTCGTAAATTTAATGAAACCCAAATAAAGCAAGCTCTCAGAGGAGTATTGGAATCAGTTAAACACAATTTGGATGTGGTGAGC
CCAATTCCTGCCAATAAGGACTTATCAGAAGCTGACTTGAGAATTGTCATGTGCGCCATGTGTGGAGATCCATTTAGTGTGGATCTTATT
CTTTCACCCTTCCTTGATTCTCATTCTTGCAGTGCTGCTCAAGCTGGACAGAATAATTCCCTAATGCTTGATAAAATCATTGGTGAAAAA
AGGAGGCGAATACAGATCACAATATTATCATACCACTCTTCAATTGGAGTAAGAAAAGATGAACTAGTTCATGGGTATATATTAGTTTAC
TCTGCAAAACGGAAAGCTTCGATGGGAATGCTTCGAGCATTTCTATCAGAAGTTCAAGACACCATTCCTGTACAGCTGGTGGCAGTTACT
GACAGCCAAGCAGATTTTTTTGAAAATGAGGCTATCAAAGAGTTAATGACTGAAGGAGAACACATTGCAACTGAGATCACTGCTAAATTT
ACAGCACTGTATTCTTTATCTCAGTATCATCGGCAAACTGAGGTCTTTACTCTGTTTTTTAGTGATGTTCTAGAGAAAAAAAATATGATA
GAAAATTCTTATTTGTCTGATAATACAAGGGAATCAACCCATCAAAGTGAAGATGTTTTTCTACCATCTCCCAGAGACTGTTTTCCCTAT
AATAACTACCCTGATTCAGATGATGACACAGAAGCACCACCTCCTTATAGTCCAATTGGGGATGATGTACAGTTGCTTCCAACACCTAGT
GACCGTTCCAGATATAGATTAGATTTGGAAGGAAATGAGTATCCTATTCATAGTACCCCAAACTGTCATGACCATGAACGCAACCATAAA
GTGCCTCCACCTATTAAACCTAAACCAGTTGTACCTAAGACAAATGTGAAAAAACTCGATCCAAACCTTTTAAAAACAATTGAAGCTGGT
ATTGGTAAAAATCCAAGAAAGCAGACTTCCCGGGTGCCTTTGGCACATCCTGAAGATATGGATCCTTCAGATAACTATGCGGAACCCATT
GATACAATTTTCAAACAGAAGGGCTATTCTGATGAGATTTATGTTGTCCCAGATGATAGTCAAAATCGTATTAAAATTCGAAACTCATTT
GTAAATAACACCCAAGGAGATGAAGAAAATGGGTTTTCTGATAGAACCTCAAAAAGTCATGGGGAACGGAGGCCTTCAAAATACAAATAT
AAATCTAAAACCTTGTTTAGTAAAGCCAAGTCATACTATAGAAGAACACATTCAGATGCCAGTGATGATGAGGCTTTCACCACTTCTAAA
ACAAAAAGAAAAGGAAGACATCGTGGAAGTGAAGAAGATCCACTTCTTTCTCCTGTTGAAACTTGGAAAGGTGGTATTGATAATCCTGCA
ATCACTTCTGACCAGGAGTTAGATGATAAGAAGATGAAGAAGAAAACCCACAAAGTGAAAGAAGATAAAAAGCAGAAAAAGAAAACTAAG
AACTTCAATCCACCAACACGTAGAAATTGGGAAAGTAATTACTTTGGGATGCCCCTCCAGGATCTGGTTACAGCTGAGAAGCCCATACCA
CTATTTGTTGAGAAATGTGTGGAATTTATTGAAGATACAGCGTATTCTCAGCTATGACACAGTGGTGCAAACAACTGGAGACTCGTGGCA
CATACCATATGATGAAGACTTGGTAGAAAGATGTTCCTGTGAAGTACCAACCAAATGGCTTTGCCTCCACCAAAAGACATAGAGATTCTT
ACCTCTATGCTAAGTTTGTGTTTGGGTACCCTCTAGGTTGGCATCAGAGGCTCTTGAGCTGGTGTTTGTTTAGGGCATTGCCTCTGTCCT

>6139_6139_2_ARHGAP5-KIAA0391_ARHGAP5_chr14_32586493_ENST00000345122_KIAA0391_chr14_35742641_ENST00000603544_length(amino acids)=1293AA_BP=
MMAKNKEPRPPSYTISIVGLSGTEKDKGNCGVGKSCLCNRFVRSKADEYYPEHTSVLSTIDFGGRVVNNDHFLYWGDIIQNSEDGVECKI
HVIEQTEFIDDQTFLPHRSTNLQPYIKRAAASKLQSAEKLMYICTDQLGLEQDFEQKQMPEGKLNVDGFLLCIDVSQGCNRKFDDQLKFV
NNLFVQLSKSKKPVIIAATKCDECVDHYLREVQAFASNKKNLLVVETSARFNVNIETCFTALVQMLDKTRSKPKIIPYLDAYKTQRQLVV
TATDKFEKLVQTVRDYHATWKTVSNKLKNHPDYEEYINLEGTRKARNTFSKHIEQLKQEHIRKRREEYINTLPRAFNTLLPNLEEIEHLN
WSEALKLMEKRADFQLCFVVLEKTPWDETDHIDKINDRRIPFDLLSTLEAEKVYQNHVQHLISEKRRVEMKEKFKKTLEKIQFISPGQPW
EEVMCFVMEDEAYKYITEADSKEVYGRHQREIVEKAKEEFQEMLFEHSELFYDLDLNATPSSDKMSEIHTVLSEEPRYKALQKLAPDRES
LLLKHIGFVYHPTKETCLSGQNCTDIKVEQLLASSLLQLDHGRLRLYHDSTNIDKVNLFILGKDGLAQELANEIRTQSTDDEYALDGKIY
ELDLRPVDAKSPYFLSQLWTAAFKPHGCFCVFNSIESLSFIGEFIGKIRTEASQIRKDKYMANLPFTLILANQRDSISKNLPILRHQGQQ
LANKLQCPFVDVPAGTYPRKFNETQIKQALRGVLESVKHNLDVVSPIPANKDLSEADLRIVMCAMCGDPFSVDLILSPFLDSHSCSAAQA
GQNNSLMLDKIIGEKRRRIQITILSYHSSIGVRKDELVHGYILVYSAKRKASMGMLRAFLSEVQDTIPVQLVAVTDSQADFFENEAIKEL
MTEGEHIATEITAKFTALYSLSQYHRQTEVFTLFFSDVLEKKNMIENSYLSDNTRESTHQSEDVFLPSPRDCFPYNNYPDSDDDTEAPPP
YSPIGDDVQLLPTPSDRSRYRLDLEGNEYPIHSTPNCHDHERNHKVPPPIKPKPVVPKTNVKKLDPNLLKTIEAGIGKNPRKQTSRVPLA
HPEDMDPSDNYAEPIDTIFKQKGYSDEIYVVPDDSQNRIKIRNSFVNNTQGDEENGFSDRTSKSHGERRPSKYKYKSKTLFSKAKSYYRR
THSDASDDEAFTTSKTKRKGRHRGSEEDPLLSPVETWKGGIDNPAITSDQELDDKKMKKKTHKVKEDKKQKKKTKNFNPPTRRNWESNYF

--------------------------------------------------------------
>6139_6139_3_ARHGAP5-KIAA0391_ARHGAP5_chr14_32586493_ENST00000432921_KIAA0391_chr14_35742641_ENST00000557565_length(transcript)=6033nt_BP=4177nt
CTCGGTGAGCGCGCCGAGGAAGAGAGGCGAGCGGAGAGTGGAGGAGGAGGCGGCGGCGGCGGGAGCGGTCCCCAGGAATGTCGCTGCCGC
CGCCACCGCCGGGGCCGCTGCCGTTGAGGAGGAGACGGAGGAGACCGACGTTGTTAGGAAGATGATCCCTATGATCTTGAAGATGTTTCT
GCACAGAAATGAGGGAAATACAAAGAACCAAATACAGTTCTGAAATTTGGGATCTGTATTTTGAGATGATTTTATTTTCAGAATGAGAAG
CATATCTGGTTACCTTTATGAATGTAGAGACATGAGAAGAGAGTTATGATGGCAAAAAACAAAGAGCCTCGTCCCCCATCCTATACCATC
AGTATAGTTGGACTCTCTGGGACTGAAAAAGACAAAGGTAACTGTGGAGTTGGAAAGTCTTGTTTGTGCAATAGATTTGTACGCTCAAAA
GCAGATGAATATTATCCAGAGCATACTTCTGTGCTTAGCACCATTGACTTTGGAGGACGAGTAGTAAACAATGATCACTTTTTGTACTGG
GGTGACATAATACAAAATAGTGAAGATGGAGTAGAATGCAAAATTCATGTCATTGAACAAACAGAGTTCATTGATGACCAGACTTTCTTG
CCTCATCGGAGTACGAATTTGCAACCATATATAAAACGTGCAGCTGCATCTAAATTGCAGTCAGCAGAAAAACTAATGTACATTTGCACT
GATCAGCTAGGCTTAGAACAAGACTTTGAACAGAAGCAAATGCCTGAAGGGAAGCTCAACGTAGATGGATTTTTATTATGCATTGATGTA
AGTCAAGGATGCAATAGGAAGTTTGATGATCAACTTAAATTTGTGAATAACCTTTTTGTCCAGTTATCAAAATCAAAAAAACCTGTAATA
ATAGCAGCAACTAAATGTGATGAATGCGTGGATCATTATCTTAGAGAAGTTCAGGCATTTGCTTCAAATAAAAAGAACCTTCTTGTAGTG
GAAACATCAGCACGATTTAATGTCAACATTGAAACATGTTTTACTGCACTGGTACAAATGTTGGATAAAACTCGTAGCAAGCCTAAAATT
ATTCCCTATTTGGATGCTTATAAAACACAGAGACAACTTGTTGTCACAGCAACAGATAAGTTTGAAAAACTTGTGCAGACTGTGAGAGAT
TATCATGCAACTTGGAAAACTGTTAGTAATAAATTAAAAAATCATCCTGATTATGAAGAATACATCAACTTAGAGGGAACAAGAAAGGCC
AGAAATACATTCTCAAAACATATAGAACAACTTAAACAGGAACATATAAGAAAAAGGAGAGAAGAGTATATAAATACTTTACCAAGAGCT
TTTAACACTCTTTTGCCAAATCTAGAAGAGATTGAACATTTGAATTGGTCAGAAGCTTTGAAGTTAATGGAAAAGAGAGCAGATTTCCAG
TTATGTTTTGTGGTGCTAGAAAAAACTCCTTGGGATGAAACTGACCATATAGACAAAATTAATGATAGGCGGATTCCATTTGACCTCCTG
AGCACTTTAGAAGCTGAAAAAGTCTATCAGAACCATGTACAGCATCTGATATCCGAGAAGAGGAGGGTGGAAATGAAGGAAAAATTCAAA
AAGACTTTGGAAAAAATTCAATTCATTTCACCAGGGCAGCCATGGGAGGAAGTTATGTGCTTTGTTATGGAGGATGAAGCCTACAAATAT
ATCACTGAGGCTGATAGCAAAGAGGTATATGGTAGGCATCAGCGAGAAATAGTTGAAAAAGCCAAAGAAGAGTTTCAAGAAATGCTTTTT
GAGCATTCTGAACTTTTTTATGATTTAGATCTTAATGCAACACCTAGTTCAGATAAAATGAGTGAAATTCATACAGTTCTGAGTGAAGAA
CCTAGATATAAAGCTTTACAGAAACTTGCACCTGATAGGGAATCCCTTCTACTTAAGCATATAGGATTTGTTTATCATCCCACTAAAGAA
ACATGTCTTAGTGGCCAAAATTGTACAGACATTAAAGTGGAGCAGTTACTTGCTAGTAGTCTTTTACAGTTGGATCATGGCCGCTTAAGA
TTATATCACGATAGTACCAATATAGATAAAGTTAACCTTTTTATTTTAGGGAAGGATGGCCTTGCCCAAGAACTAGCAAATGAGATAAGG
ACACAATCCACTGATGATGAGTATGCCTTAGATGGAAAAATTTATGAACTTGATCTTCGGCCGGTTGATGCCAAATCGCCTTACTTTTTG
AGTCAGTTATGGACTGCCGCCTTTAAACCACATGGGTGCTTCTGTGTATTTAATTCCATTGAGTCATTGAGTTTTATTGGGGAATTTATT
GGGAAAATAAGAACTGAAGCTTCTCAGATCAGAAAAGATAAATACATGGCTAATCTTCCATTTACATTAATTCTGGCTAATCAGAGAGAT
TCCATTAGTAAGAATCTACCAATTCTCAGGCACCAAGGGCAGCAGTTGGCAAACAAGTTGCAATGTCCTTTTGTAGATGTACCTGCTGGT
ACATATCCTCGTAAATTTAATGAAACCCAAATAAAGCAAGCTCTCAGAGGAGTATTGGAATCAGTTAAACACAATTTGGATGTGGTGAGC
CCAATTCCTGCCAATAAGGACTTATCAGAAGCTGACTTGAGAATTGTCATGTGCGCCATGTGTGGAGATCCATTTAGTGTGGATCTTATT
CTTTCACCCTTCCTTGATTCTCATTCTTGCAGTGCTGCTCAAGCTGGACAGAATAATTCCCTAATGCTTGATAAAATCATTGGTGAAAAA
AGGAGGCGAATACAGATCACAATATTATCATACCACTCTTCAATTGGAGTAAGAAAAGATGAACTAGTTCATGGGTATATATTAGTTTAC
TCTGCAAAACGGAAAGCTTCGATGGGAATGCTTCGAGCATTTCTATCAGAAGTTCAAGACACCATTCCTGTACAGCTGGTGGCAGTTACT
GACAGCCAAGCAGATTTTTTTGAAAATGAGGCTATCAAAGAGTTAATGACTGAAGGAGAACACATTGCAACTGAGATCACTGCTAAATTT
ACAGCACTGTATTCTTTATCTCAGTATCATCGGCAAACTGAGGTCTTTACTCTGTTTTTTAGTGATGTTCTAGAGAAAAAAAATATGATA
GAAAATTCTTATTTGTCTGATAATACAAGGGAATCAACCCATCAAAGTGAAGATGTTTTTCTACCATCTCCCAGAGACTGTTTTCCCTAT
AATAACTACCCTGATTCAGATGATGACACAGAAGCACCACCTCCTTATAGTCCAATTGGGGATGATGTACAGTTGCTTCCAACACCTAGT
GACCGTTCCAGATATAGATTAGATTTGGAAGGAAATGAGTATCCTATTCATAGTACCCCAAACTGTCATGACCATGAACGCAACCATAAA
GTGCCTCCACCTATTAAACCTAAACCAGTTGTACCTAAGACAAATGTGAAAAAACTCGATCCAAACCTTTTAAAAACAATTGAAGCTGGT
ATTGGTAAAAATCCAAGAAAGCAGACTTCCCGGGTGCCTTTGGCACATCCTGAAGATATGGATCCTTCAGATAACTATGCGGAACCCATT
GATACAATTTTCAAACAGAAGGGCTATTCTGATGAGATTTATGTTGTCCCAGATGATAGTCAAAATCGTATTAAAATTCGAAACTCATTT
GTAAATAACACCCAAGGAGATGAAGAAAATGGGTTTTCTGATAGAACCTCAAAAAGTCATGGGGAACGGAGGCCTTCAAAATACAAATAT
AAATCTAAAACCTTGTTTAGTAAAGCCAAGTCATACTATAGAAGAACACATTCAGATGCCAGTGATGATGAGGCTTTCACCACTTCTAAA
ACAAAAAGAAAAGGAAGACATCGTGGAAGTGAAGAAGATCCACTTCTTTCTCCTGTTGAAACTTGGAAAGGTGGTATTGATAATCCTGCA
ATCACTTCTGACCAGGAGTTAGATGATAAGAAGATGAAGAAGAAAACCCACAAAGTGAAAGAAGATAAAAAGAAAAAGAAAACTAAGAAC
TTCAATCCACCAACACGTAGAAATTGGGAAAGTAATTACTTTGGGATGCCCCTCCAGGATCTGGTTACAGCTGAGAAGCCCATACCACTA
TTTGTTGAGAAATGTGTGGAATTTATTGAAGATACAGCGTATTCTCAGCTATGACACAGTGGTGCAAACAACTGGAGACTCGTGGCACAT
ACCATATGATGAAGACTTGGTAGAAAGATGTTCCTGTGAAGTACCAACCAAATGGCTTTGCCTCCACCAAAAGACATAGAGATTCTTACC
TCTATGCTAAGTTTGTGTTTGGGTACCCTCTAGGTTGGCATCAGAGGCTCTTGAGCTGGTGTTTGTTTAGGGCATTGCCTCTGTCCTGAA
GATAAAAGGATTCTATTAACAGCATTGACATTGATTTTTTAATGAAATGAGATATATCTTTTCATAACCAGCTGCGTTTTTTTCCCCTAA
CATTTGTTTTTGGAGGCTTATCAAGAGTTGGAGAACTTAGTGTAGAGCAAAACCTGCATTTCTCCTACTGGGCCAGCTATTCCACTTAGC
TTGGGTGACTAATAGTGCTTTTGGTATCCATTTTTTGCTACTTCTGACCTTGCCTTCCAGGCCTACCAATAGCAGAATCAATCCATCTGT
CCCTGAGATACTCATGTTGTTTCAAATGCCTCCTCCCATTTCTGGCATAGTCTCATTCTCTGTATGTTATGCCCTATCCACATGGAATCA
TTTATCGTCCTCTGTAATAAACTGGCCAAGATACTAAAGGCTTACTATTCATAGCAGTTTTTAATTACTTATCATCCAATTATTTGGATT
GGAGAAGAGGGGGCATTCACTCCTCTTTTTCTTATTTTTTTTGGAAATAGAGTCTCAACTTACTCTGTCGCCAGGGCTGGAGTGCAGTGA
CGTGATCACAGTTCACTGCAGCCTCAAACTCCCAGGCTCAAGCAATCTTCCTACCTCAGCCCTCCTGAGTAATTGGGACTACAGAACAGA
GAATGTCAGTATCCAATAGGATGCCAGTGGAATTCCCTGACGATTCCATCCATGCGGCTCTGCTGGAGCAGGGTAGTGTCCTAGGCTGGG
AGAATGGGATGGAGCCTCCACCTCATGAAGTAGCTTCCTTTGGAGGTGGCTATGGCAGGTCTTCGGAGAGAATATGCTTTTAAGGCTATT
AACCAGGGTGGCCTTACATCAGTAGCTGTCAGAGGGAAAGACTGTGCAGTAATTGTCACACAGAAGAAAGTACCTGACAAATTATTGGAT
TCCAGCACAGTGACTCACTTATTCAAGATAACTGAAAACATTGGTTGTGTGATGACCGGAATGACAGCTGACAGCAGATCCCAGGTACAG
AGGGCACGCTATGAGGCAGCTAACTGGAAATACAAGTATGGCTATGAGATTCCTGTGGACATGCTGTGTAAAAGAATTGCCGATATTTCT
CAGGTCTACACACAGAATGCTGAAATGAGGCCTCTTGGTTGTTGTATGATTTTAATTGGTATAGATGAAGAGCAAGGCCCTCAGGTATAT
AAGTGTGATCCTGCAGGTTACTACTGTGGGTTTAAAGCCACTGCAGCGGGAGTTAAACAAACTGAGTCAACCAGCTTCCTTGAAAAAAAA
GTGAAGAAGAAATTTGATTGGACATTTGAACAGACAGTGGAAACTGCAATTACATGCCTGTCTACTGTTCTATCAATTGATTTCAAACCT
TCAGAAATAGAAGTTGGAGTAGTGACAGTTGAAAATCCTAAATTCAGGATTCTTACAGAAGCAGAGATTGATGCTCACCTTGTTGCTCTA
GCAGAGAGAGACTAAACATTGTCGTTAGTTTACCAGATCCGTGATGCCACTTACCTGTGTGTTTGGTAACAACAAACCAACATCATGGAG
GTCCCTGGATTGAAAAAGGAGCCTCTCCCACTCCTCCTACCACCGAAGTGGTTAGGACTCTATATAAATAAAAACAAGGCTTTTGGAAAA

>6139_6139_3_ARHGAP5-KIAA0391_ARHGAP5_chr14_32586493_ENST00000432921_KIAA0391_chr14_35742641_ENST00000557565_length(amino acids)=1292AA_BP=
MMAKNKEPRPPSYTISIVGLSGTEKDKGNCGVGKSCLCNRFVRSKADEYYPEHTSVLSTIDFGGRVVNNDHFLYWGDIIQNSEDGVECKI
HVIEQTEFIDDQTFLPHRSTNLQPYIKRAAASKLQSAEKLMYICTDQLGLEQDFEQKQMPEGKLNVDGFLLCIDVSQGCNRKFDDQLKFV
NNLFVQLSKSKKPVIIAATKCDECVDHYLREVQAFASNKKNLLVVETSARFNVNIETCFTALVQMLDKTRSKPKIIPYLDAYKTQRQLVV
TATDKFEKLVQTVRDYHATWKTVSNKLKNHPDYEEYINLEGTRKARNTFSKHIEQLKQEHIRKRREEYINTLPRAFNTLLPNLEEIEHLN
WSEALKLMEKRADFQLCFVVLEKTPWDETDHIDKINDRRIPFDLLSTLEAEKVYQNHVQHLISEKRRVEMKEKFKKTLEKIQFISPGQPW
EEVMCFVMEDEAYKYITEADSKEVYGRHQREIVEKAKEEFQEMLFEHSELFYDLDLNATPSSDKMSEIHTVLSEEPRYKALQKLAPDRES
LLLKHIGFVYHPTKETCLSGQNCTDIKVEQLLASSLLQLDHGRLRLYHDSTNIDKVNLFILGKDGLAQELANEIRTQSTDDEYALDGKIY
ELDLRPVDAKSPYFLSQLWTAAFKPHGCFCVFNSIESLSFIGEFIGKIRTEASQIRKDKYMANLPFTLILANQRDSISKNLPILRHQGQQ
LANKLQCPFVDVPAGTYPRKFNETQIKQALRGVLESVKHNLDVVSPIPANKDLSEADLRIVMCAMCGDPFSVDLILSPFLDSHSCSAAQA
GQNNSLMLDKIIGEKRRRIQITILSYHSSIGVRKDELVHGYILVYSAKRKASMGMLRAFLSEVQDTIPVQLVAVTDSQADFFENEAIKEL
MTEGEHIATEITAKFTALYSLSQYHRQTEVFTLFFSDVLEKKNMIENSYLSDNTRESTHQSEDVFLPSPRDCFPYNNYPDSDDDTEAPPP
YSPIGDDVQLLPTPSDRSRYRLDLEGNEYPIHSTPNCHDHERNHKVPPPIKPKPVVPKTNVKKLDPNLLKTIEAGIGKNPRKQTSRVPLA
HPEDMDPSDNYAEPIDTIFKQKGYSDEIYVVPDDSQNRIKIRNSFVNNTQGDEENGFSDRTSKSHGERRPSKYKYKSKTLFSKAKSYYRR
THSDASDDEAFTTSKTKRKGRHRGSEEDPLLSPVETWKGGIDNPAITSDQELDDKKMKKKTHKVKEDKKKKKTKNFNPPTRRNWESNYFG

--------------------------------------------------------------
>6139_6139_4_ARHGAP5-KIAA0391_ARHGAP5_chr14_32586493_ENST00000432921_KIAA0391_chr14_35742641_ENST00000603544_length(transcript)=4413nt_BP=4177nt
CTCGGTGAGCGCGCCGAGGAAGAGAGGCGAGCGGAGAGTGGAGGAGGAGGCGGCGGCGGCGGGAGCGGTCCCCAGGAATGTCGCTGCCGC
CGCCACCGCCGGGGCCGCTGCCGTTGAGGAGGAGACGGAGGAGACCGACGTTGTTAGGAAGATGATCCCTATGATCTTGAAGATGTTTCT
GCACAGAAATGAGGGAAATACAAAGAACCAAATACAGTTCTGAAATTTGGGATCTGTATTTTGAGATGATTTTATTTTCAGAATGAGAAG
CATATCTGGTTACCTTTATGAATGTAGAGACATGAGAAGAGAGTTATGATGGCAAAAAACAAAGAGCCTCGTCCCCCATCCTATACCATC
AGTATAGTTGGACTCTCTGGGACTGAAAAAGACAAAGGTAACTGTGGAGTTGGAAAGTCTTGTTTGTGCAATAGATTTGTACGCTCAAAA
GCAGATGAATATTATCCAGAGCATACTTCTGTGCTTAGCACCATTGACTTTGGAGGACGAGTAGTAAACAATGATCACTTTTTGTACTGG
GGTGACATAATACAAAATAGTGAAGATGGAGTAGAATGCAAAATTCATGTCATTGAACAAACAGAGTTCATTGATGACCAGACTTTCTTG
CCTCATCGGAGTACGAATTTGCAACCATATATAAAACGTGCAGCTGCATCTAAATTGCAGTCAGCAGAAAAACTAATGTACATTTGCACT
GATCAGCTAGGCTTAGAACAAGACTTTGAACAGAAGCAAATGCCTGAAGGGAAGCTCAACGTAGATGGATTTTTATTATGCATTGATGTA
AGTCAAGGATGCAATAGGAAGTTTGATGATCAACTTAAATTTGTGAATAACCTTTTTGTCCAGTTATCAAAATCAAAAAAACCTGTAATA
ATAGCAGCAACTAAATGTGATGAATGCGTGGATCATTATCTTAGAGAAGTTCAGGCATTTGCTTCAAATAAAAAGAACCTTCTTGTAGTG
GAAACATCAGCACGATTTAATGTCAACATTGAAACATGTTTTACTGCACTGGTACAAATGTTGGATAAAACTCGTAGCAAGCCTAAAATT
ATTCCCTATTTGGATGCTTATAAAACACAGAGACAACTTGTTGTCACAGCAACAGATAAGTTTGAAAAACTTGTGCAGACTGTGAGAGAT
TATCATGCAACTTGGAAAACTGTTAGTAATAAATTAAAAAATCATCCTGATTATGAAGAATACATCAACTTAGAGGGAACAAGAAAGGCC
AGAAATACATTCTCAAAACATATAGAACAACTTAAACAGGAACATATAAGAAAAAGGAGAGAAGAGTATATAAATACTTTACCAAGAGCT
TTTAACACTCTTTTGCCAAATCTAGAAGAGATTGAACATTTGAATTGGTCAGAAGCTTTGAAGTTAATGGAAAAGAGAGCAGATTTCCAG
TTATGTTTTGTGGTGCTAGAAAAAACTCCTTGGGATGAAACTGACCATATAGACAAAATTAATGATAGGCGGATTCCATTTGACCTCCTG
AGCACTTTAGAAGCTGAAAAAGTCTATCAGAACCATGTACAGCATCTGATATCCGAGAAGAGGAGGGTGGAAATGAAGGAAAAATTCAAA
AAGACTTTGGAAAAAATTCAATTCATTTCACCAGGGCAGCCATGGGAGGAAGTTATGTGCTTTGTTATGGAGGATGAAGCCTACAAATAT
ATCACTGAGGCTGATAGCAAAGAGGTATATGGTAGGCATCAGCGAGAAATAGTTGAAAAAGCCAAAGAAGAGTTTCAAGAAATGCTTTTT
GAGCATTCTGAACTTTTTTATGATTTAGATCTTAATGCAACACCTAGTTCAGATAAAATGAGTGAAATTCATACAGTTCTGAGTGAAGAA
CCTAGATATAAAGCTTTACAGAAACTTGCACCTGATAGGGAATCCCTTCTACTTAAGCATATAGGATTTGTTTATCATCCCACTAAAGAA
ACATGTCTTAGTGGCCAAAATTGTACAGACATTAAAGTGGAGCAGTTACTTGCTAGTAGTCTTTTACAGTTGGATCATGGCCGCTTAAGA
TTATATCACGATAGTACCAATATAGATAAAGTTAACCTTTTTATTTTAGGGAAGGATGGCCTTGCCCAAGAACTAGCAAATGAGATAAGG
ACACAATCCACTGATGATGAGTATGCCTTAGATGGAAAAATTTATGAACTTGATCTTCGGCCGGTTGATGCCAAATCGCCTTACTTTTTG
AGTCAGTTATGGACTGCCGCCTTTAAACCACATGGGTGCTTCTGTGTATTTAATTCCATTGAGTCATTGAGTTTTATTGGGGAATTTATT
GGGAAAATAAGAACTGAAGCTTCTCAGATCAGAAAAGATAAATACATGGCTAATCTTCCATTTACATTAATTCTGGCTAATCAGAGAGAT
TCCATTAGTAAGAATCTACCAATTCTCAGGCACCAAGGGCAGCAGTTGGCAAACAAGTTGCAATGTCCTTTTGTAGATGTACCTGCTGGT
ACATATCCTCGTAAATTTAATGAAACCCAAATAAAGCAAGCTCTCAGAGGAGTATTGGAATCAGTTAAACACAATTTGGATGTGGTGAGC
CCAATTCCTGCCAATAAGGACTTATCAGAAGCTGACTTGAGAATTGTCATGTGCGCCATGTGTGGAGATCCATTTAGTGTGGATCTTATT
CTTTCACCCTTCCTTGATTCTCATTCTTGCAGTGCTGCTCAAGCTGGACAGAATAATTCCCTAATGCTTGATAAAATCATTGGTGAAAAA
AGGAGGCGAATACAGATCACAATATTATCATACCACTCTTCAATTGGAGTAAGAAAAGATGAACTAGTTCATGGGTATATATTAGTTTAC
TCTGCAAAACGGAAAGCTTCGATGGGAATGCTTCGAGCATTTCTATCAGAAGTTCAAGACACCATTCCTGTACAGCTGGTGGCAGTTACT
GACAGCCAAGCAGATTTTTTTGAAAATGAGGCTATCAAAGAGTTAATGACTGAAGGAGAACACATTGCAACTGAGATCACTGCTAAATTT
ACAGCACTGTATTCTTTATCTCAGTATCATCGGCAAACTGAGGTCTTTACTCTGTTTTTTAGTGATGTTCTAGAGAAAAAAAATATGATA
GAAAATTCTTATTTGTCTGATAATACAAGGGAATCAACCCATCAAAGTGAAGATGTTTTTCTACCATCTCCCAGAGACTGTTTTCCCTAT
AATAACTACCCTGATTCAGATGATGACACAGAAGCACCACCTCCTTATAGTCCAATTGGGGATGATGTACAGTTGCTTCCAACACCTAGT
GACCGTTCCAGATATAGATTAGATTTGGAAGGAAATGAGTATCCTATTCATAGTACCCCAAACTGTCATGACCATGAACGCAACCATAAA
GTGCCTCCACCTATTAAACCTAAACCAGTTGTACCTAAGACAAATGTGAAAAAACTCGATCCAAACCTTTTAAAAACAATTGAAGCTGGT
ATTGGTAAAAATCCAAGAAAGCAGACTTCCCGGGTGCCTTTGGCACATCCTGAAGATATGGATCCTTCAGATAACTATGCGGAACCCATT
GATACAATTTTCAAACAGAAGGGCTATTCTGATGAGATTTATGTTGTCCCAGATGATAGTCAAAATCGTATTAAAATTCGAAACTCATTT
GTAAATAACACCCAAGGAGATGAAGAAAATGGGTTTTCTGATAGAACCTCAAAAAGTCATGGGGAACGGAGGCCTTCAAAATACAAATAT
AAATCTAAAACCTTGTTTAGTAAAGCCAAGTCATACTATAGAAGAACACATTCAGATGCCAGTGATGATGAGGCTTTCACCACTTCTAAA
ACAAAAAGAAAAGGAAGACATCGTGGAAGTGAAGAAGATCCACTTCTTTCTCCTGTTGAAACTTGGAAAGGTGGTATTGATAATCCTGCA
ATCACTTCTGACCAGGAGTTAGATGATAAGAAGATGAAGAAGAAAACCCACAAAGTGAAAGAAGATAAAAAGAAAAAGAAAACTAAGAAC
TTCAATCCACCAACACGTAGAAATTGGGAAAGTAATTACTTTGGGATGCCCCTCCAGGATCTGGTTACAGCTGAGAAGCCCATACCACTA
TTTGTTGAGAAATGTGTGGAATTTATTGAAGATACAGCGTATTCTCAGCTATGACACAGTGGTGCAAACAACTGGAGACTCGTGGCACAT
ACCATATGATGAAGACTTGGTAGAAAGATGTTCCTGTGAAGTACCAACCAAATGGCTTTGCCTCCACCAAAAGACATAGAGATTCTTACC
TCTATGCTAAGTTTGTGTTTGGGTACCCTCTAGGTTGGCATCAGAGGCTCTTGAGCTGGTGTTTGTTTAGGGCATTGCCTCTGTCCTGAA

>6139_6139_4_ARHGAP5-KIAA0391_ARHGAP5_chr14_32586493_ENST00000432921_KIAA0391_chr14_35742641_ENST00000603544_length(amino acids)=1292AA_BP=
MMAKNKEPRPPSYTISIVGLSGTEKDKGNCGVGKSCLCNRFVRSKADEYYPEHTSVLSTIDFGGRVVNNDHFLYWGDIIQNSEDGVECKI
HVIEQTEFIDDQTFLPHRSTNLQPYIKRAAASKLQSAEKLMYICTDQLGLEQDFEQKQMPEGKLNVDGFLLCIDVSQGCNRKFDDQLKFV
NNLFVQLSKSKKPVIIAATKCDECVDHYLREVQAFASNKKNLLVVETSARFNVNIETCFTALVQMLDKTRSKPKIIPYLDAYKTQRQLVV
TATDKFEKLVQTVRDYHATWKTVSNKLKNHPDYEEYINLEGTRKARNTFSKHIEQLKQEHIRKRREEYINTLPRAFNTLLPNLEEIEHLN
WSEALKLMEKRADFQLCFVVLEKTPWDETDHIDKINDRRIPFDLLSTLEAEKVYQNHVQHLISEKRRVEMKEKFKKTLEKIQFISPGQPW
EEVMCFVMEDEAYKYITEADSKEVYGRHQREIVEKAKEEFQEMLFEHSELFYDLDLNATPSSDKMSEIHTVLSEEPRYKALQKLAPDRES
LLLKHIGFVYHPTKETCLSGQNCTDIKVEQLLASSLLQLDHGRLRLYHDSTNIDKVNLFILGKDGLAQELANEIRTQSTDDEYALDGKIY
ELDLRPVDAKSPYFLSQLWTAAFKPHGCFCVFNSIESLSFIGEFIGKIRTEASQIRKDKYMANLPFTLILANQRDSISKNLPILRHQGQQ
LANKLQCPFVDVPAGTYPRKFNETQIKQALRGVLESVKHNLDVVSPIPANKDLSEADLRIVMCAMCGDPFSVDLILSPFLDSHSCSAAQA
GQNNSLMLDKIIGEKRRRIQITILSYHSSIGVRKDELVHGYILVYSAKRKASMGMLRAFLSEVQDTIPVQLVAVTDSQADFFENEAIKEL
MTEGEHIATEITAKFTALYSLSQYHRQTEVFTLFFSDVLEKKNMIENSYLSDNTRESTHQSEDVFLPSPRDCFPYNNYPDSDDDTEAPPP
YSPIGDDVQLLPTPSDRSRYRLDLEGNEYPIHSTPNCHDHERNHKVPPPIKPKPVVPKTNVKKLDPNLLKTIEAGIGKNPRKQTSRVPLA
HPEDMDPSDNYAEPIDTIFKQKGYSDEIYVVPDDSQNRIKIRNSFVNNTQGDEENGFSDRTSKSHGERRPSKYKYKSKTLFSKAKSYYRR
THSDASDDEAFTTSKTKRKGRHRGSEEDPLLSPVETWKGGIDNPAITSDQELDDKKMKKKTHKVKEDKKKKKTKNFNPPTRRNWESNYFG

--------------------------------------------------------------
>6139_6139_5_ARHGAP5-KIAA0391_ARHGAP5_chr14_32586493_ENST00000433497_KIAA0391_chr14_35742641_ENST00000557565_length(transcript)=2128nt_BP=272nt
AGAGAGGCGAGCGGAGAGTGGAGGAGGAGGCGGCGGCGGCGGGAGCGGTCCCCAGGAATGTCGCTGCCGCCGCCACCGCCGGGGCCGCTG
CCGTTGAGGAGGAGACGGAGGAGACCGACGTTGTTAGAAAAAGAAAACTAAGAACTTCAATCCACCAACACGTAGAAATTGGGAAAGTAA
TTACTTTGGGATGCCCCTCCAGGATCTGGTTACAGCTGAGAAGCCCATACCACTATTTGTTGAGAAATGTGTGGAATTTATTGAAGATAC
AGCGTATTCTCAGCTATGACACAGTGGTGCAAACAACTGGAGACTCGTGGCACATACCATATGATGAAGACTTGGTAGAAAGATGTTCCT
GTGAAGTACCAACCAAATGGCTTTGCCTCCACCAAAAGACATAGAGATTCTTACCTCTATGCTAAGTTTGTGTTTGGGTACCCTCTAGGT
TGGCATCAGAGGCTCTTGAGCTGGTGTTTGTTTAGGGCATTGCCTCTGTCCTGAAGATAAAAGGATTCTATTAACAGCATTGACATTGAT
TTTTTAATGAAATGAGATATATCTTTTCATAACCAGCTGCGTTTTTTTCCCCTAACATTTGTTTTTGGAGGCTTATCAAGAGTTGGAGAA
CTTAGTGTAGAGCAAAACCTGCATTTCTCCTACTGGGCCAGCTATTCCACTTAGCTTGGGTGACTAATAGTGCTTTTGGTATCCATTTTT
TGCTACTTCTGACCTTGCCTTCCAGGCCTACCAATAGCAGAATCAATCCATCTGTCCCTGAGATACTCATGTTGTTTCAAATGCCTCCTC
CCATTTCTGGCATAGTCTCATTCTCTGTATGTTATGCCCTATCCACATGGAATCATTTATCGTCCTCTGTAATAAACTGGCCAAGATACT
AAAGGCTTACTATTCATAGCAGTTTTTAATTACTTATCATCCAATTATTTGGATTGGAGAAGAGGGGGCATTCACTCCTCTTTTTCTTAT
TTTTTTTGGAAATAGAGTCTCAACTTACTCTGTCGCCAGGGCTGGAGTGCAGTGACGTGATCACAGTTCACTGCAGCCTCAAACTCCCAG
GCTCAAGCAATCTTCCTACCTCAGCCCTCCTGAGTAATTGGGACTACAGAACAGAGAATGTCAGTATCCAATAGGATGCCAGTGGAATTC
CCTGACGATTCCATCCATGCGGCTCTGCTGGAGCAGGGTAGTGTCCTAGGCTGGGAGAATGGGATGGAGCCTCCACCTCATGAAGTAGCT
TCCTTTGGAGGTGGCTATGGCAGGTCTTCGGAGAGAATATGCTTTTAAGGCTATTAACCAGGGTGGCCTTACATCAGTAGCTGTCAGAGG
GAAAGACTGTGCAGTAATTGTCACACAGAAGAAAGTACCTGACAAATTATTGGATTCCAGCACAGTGACTCACTTATTCAAGATAACTGA
AAACATTGGTTGTGTGATGACCGGAATGACAGCTGACAGCAGATCCCAGGTACAGAGGGCACGCTATGAGGCAGCTAACTGGAAATACAA
GTATGGCTATGAGATTCCTGTGGACATGCTGTGTAAAAGAATTGCCGATATTTCTCAGGTCTACACACAGAATGCTGAAATGAGGCCTCT
TGGTTGTTGTATGATTTTAATTGGTATAGATGAAGAGCAAGGCCCTCAGGTATATAAGTGTGATCCTGCAGGTTACTACTGTGGGTTTAA
AGCCACTGCAGCGGGAGTTAAACAAACTGAGTCAACCAGCTTCCTTGAAAAAAAAGTGAAGAAGAAATTTGATTGGACATTTGAACAGAC
AGTGGAAACTGCAATTACATGCCTGTCTACTGTTCTATCAATTGATTTCAAACCTTCAGAAATAGAAGTTGGAGTAGTGACAGTTGAAAA
TCCTAAATTCAGGATTCTTACAGAAGCAGAGATTGATGCTCACCTTGTTGCTCTAGCAGAGAGAGACTAAACATTGTCGTTAGTTTACCA
GATCCGTGATGCCACTTACCTGTGTGTTTGGTAACAACAAACCAACATCATGGAGGTCCCTGGATTGAAAAAGGAGCCTCTCCCACTCCT

>6139_6139_5_ARHGAP5-KIAA0391_ARHGAP5_chr14_32586493_ENST00000433497_KIAA0391_chr14_35742641_ENST00000557565_length(amino acids)=231AA_BP=
MEVAMAGLRREYAFKAINQGGLTSVAVRGKDCAVIVTQKKVPDKLLDSSTVTHLFKITENIGCVMTGMTADSRSQVQRARYEAANWKYKY
GYEIPVDMLCKRIADISQVYTQNAEMRPLGCCMILIGIDEEQGPQVYKCDPAGYYCGFKATAAGVKQTESTSFLEKKVKKKFDWTFEQTV

--------------------------------------------------------------
>6139_6139_6_ARHGAP5-KIAA0391_ARHGAP5_chr14_32586493_ENST00000433497_KIAA0391_chr14_35742641_ENST00000603544_length(transcript)=508nt_BP=272nt
AGAGAGGCGAGCGGAGAGTGGAGGAGGAGGCGGCGGCGGCGGGAGCGGTCCCCAGGAATGTCGCTGCCGCCGCCACCGCCGGGGCCGCTG
CCGTTGAGGAGGAGACGGAGGAGACCGACGTTGTTAGAAAAAGAAAACTAAGAACTTCAATCCACCAACACGTAGAAATTGGGAAAGTAA
TTACTTTGGGATGCCCCTCCAGGATCTGGTTACAGCTGAGAAGCCCATACCACTATTTGTTGAGAAATGTGTGGAATTTATTGAAGATAC
AGCGTATTCTCAGCTATGACACAGTGGTGCAAACAACTGGAGACTCGTGGCACATACCATATGATGAAGACTTGGTAGAAAGATGTTCCT
GTGAAGTACCAACCAAATGGCTTTGCCTCCACCAAAAGACATAGAGATTCTTACCTCTATGCTAAGTTTGTGTTTGGGTACCCTCTAGGT

>6139_6139_6_ARHGAP5-KIAA0391_ARHGAP5_chr14_32586493_ENST00000433497_KIAA0391_chr14_35742641_ENST00000603544_length(amino acids)=72AA_BP=28

--------------------------------------------------------------
>6139_6139_7_ARHGAP5-KIAA0391_ARHGAP5_chr14_32586493_ENST00000539826_KIAA0391_chr14_35742641_ENST00000557565_length(transcript)=5958nt_BP=4102nt
CTGCGCCGCCGCGCCGCCGCTCCGCCCCCGGTCGGGTGTGTGGCTGCGCGCGCCGGGAGAGATGCTGAGGAAGATGATCCCTATGATCTT
GAAGATGTTTCTGCACAGAAATGAGGGAAATACAAAGAACCAAATACAGTTCTGAAATTTGGGATCTGTATTTTGAGATGATTTTATTTT
CAGAATGAGAAGCATATCTGGTTACCTTTATGAATGTAGAGACATGAGAAGAGAGTTATGATGGCAAAAAACAAAGAGCCTCGTCCCCCA
TCCTATACCATCAGTATAGTTGGACTCTCTGGGACTGAAAAAGACAAAGGTAACTGTGGAGTTGGAAAGTCTTGTTTGTGCAATAGATTT
GTACGCTCAAAAGCAGATGAATATTATCCAGAGCATACTTCTGTGCTTAGCACCATTGACTTTGGAGGACGAGTAGTAAACAATGATCAC
TTTTTGTACTGGGGTGACATAATACAAAATAGTGAAGATGGAGTAGAATGCAAAATTCATGTCATTGAACAAACAGAGTTCATTGATGAC
CAGACTTTCTTGCCTCATCGGAGTACGAATTTGCAACCATATATAAAACGTGCAGCTGCATCTAAATTGCAGTCAGCAGAAAAACTAATG
TACATTTGCACTGATCAGCTAGGCTTAGAACAAGACTTTGAACAGAAGCAAATGCCTGAAGGGAAGCTCAACGTAGATGGATTTTTATTA
TGCATTGATGTAAGTCAAGGATGCAATAGGAAGTTTGATGATCAACTTAAATTTGTGAATAACCTTTTTGTCCAGTTATCAAAATCAAAA
AAACCTGTAATAATAGCAGCAACTAAATGTGATGAATGCGTGGATCATTATCTTAGAGAAGTTCAGGCATTTGCTTCAAATAAAAAGAAC
CTTCTTGTAGTGGAAACATCAGCACGATTTAATGTCAACATTGAAACATGTTTTACTGCACTGGTACAAATGTTGGATAAAACTCGTAGC
AAGCCTAAAATTATTCCCTATTTGGATGCTTATAAAACACAGAGACAACTTGTTGTCACAGCAACAGATAAGTTTGAAAAACTTGTGCAG
ACTGTGAGAGATTATCATGCAACTTGGAAAACTGTTAGTAATAAATTAAAAAATCATCCTGATTATGAAGAATACATCAACTTAGAGGGA
ACAAGAAAGGCCAGAAATACATTCTCAAAACATATAGAACAACTTAAACAGGAACATATAAGAAAAAGGAGAGAAGAGTATATAAATACT
TTACCAAGAGCTTTTAACACTCTTTTGCCAAATCTAGAAGAGATTGAACATTTGAATTGGTCAGAAGCTTTGAAGTTAATGGAAAAGAGA
GCAGATTTCCAGTTATGTTTTGTGGTGCTAGAAAAAACTCCTTGGGATGAAACTGACCATATAGACAAAATTAATGATAGGCGGATTCCA
TTTGACCTCCTGAGCACTTTAGAAGCTGAAAAAGTCTATCAGAACCATGTACAGCATCTGATATCCGAGAAGAGGAGGGTGGAAATGAAG
GAAAAATTCAAAAAGACTTTGGAAAAAATTCAATTCATTTCACCAGGGCAGCCATGGGAGGAAGTTATGTGCTTTGTTATGGAGGATGAA
GCCTACAAATATATCACTGAGGCTGATAGCAAAGAGGTATATGGTAGGCATCAGCGAGAAATAGTTGAAAAAGCCAAAGAAGAGTTTCAA
GAAATGCTTTTTGAGCATTCTGAACTTTTTTATGATTTAGATCTTAATGCAACACCTAGTTCAGATAAAATGAGTGAAATTCATACAGTT
CTGAGTGAAGAACCTAGATATAAAGCTTTACAGAAACTTGCACCTGATAGGGAATCCCTTCTACTTAAGCATATAGGATTTGTTTATCAT
CCCACTAAAGAAACATGTCTTAGTGGCCAAAATTGTACAGACATTAAAGTGGAGCAGTTACTTGCTAGTAGTCTTTTACAGTTGGATCAT
GGCCGCTTAAGATTATATCACGATAGTACCAATATAGATAAAGTTAACCTTTTTATTTTAGGGAAGGATGGCCTTGCCCAAGAACTAGCA
AATGAGATAAGGACACAATCCACTGATGATGAGTATGCCTTAGATGGAAAAATTTATGAACTTGATCTTCGGCCGGTTGATGCCAAATCG
CCTTACTTTTTGAGTCAGTTATGGACTGCCGCCTTTAAACCACATGGGTGCTTCTGTGTATTTAATTCCATTGAGTCATTGAGTTTTATT
GGGGAATTTATTGGGAAAATAAGAACTGAAGCTTCTCAGATCAGAAAAGATAAATACATGGCTAATCTTCCATTTACATTAATTCTGGCT
AATCAGAGAGATTCCATTAGTAAGAATCTACCAATTCTCAGGCACCAAGGGCAGCAGTTGGCAAACAAGTTGCAATGTCCTTTTGTAGAT
GTACCTGCTGGTACATATCCTCGTAAATTTAATGAAACCCAAATAAAGCAAGCTCTCAGAGGAGTATTGGAATCAGTTAAACACAATTTG
GATGTGGTGAGCCCAATTCCTGCCAATAAGGACTTATCAGAAGCTGACTTGAGAATTGTCATGTGCGCCATGTGTGGAGATCCATTTAGT
GTGGATCTTATTCTTTCACCCTTCCTTGATTCTCATTCTTGCAGTGCTGCTCAAGCTGGACAGAATAATTCCCTAATGCTTGATAAAATC
ATTGGTGAAAAAAGGAGGCGAATACAGATCACAATATTATCATACCACTCTTCAATTGGAGTAAGAAAAGATGAACTAGTTCATGGGTAT
ATATTAGTTTACTCTGCAAAACGGAAAGCTTCGATGGGAATGCTTCGAGCATTTCTATCAGAAGTTCAAGACACCATTCCTGTACAGCTG
GTGGCAGTTACTGACAGCCAAGCAGATTTTTTTGAAAATGAGGCTATCAAAGAGTTAATGACTGAAGGAGAACACATTGCAACTGAGATC
ACTGCTAAATTTACAGCACTGTATTCTTTATCTCAGTATCATCGGCAAACTGAGGTCTTTACTCTGTTTTTTAGTGATGTTCTAGAGAAA
AAAAATATGATAGAAAATTCTTATTTGTCTGATAATACAAGGGAATCAACCCATCAAAGTGAAGATGTTTTTCTACCATCTCCCAGAGAC
TGTTTTCCCTATAATAACTACCCTGATTCAGATGATGACACAGAAGCACCACCTCCTTATAGTCCAATTGGGGATGATGTACAGTTGCTT
CCAACACCTAGTGACCGTTCCAGATATAGATTAGATTTGGAAGGAAATGAGTATCCTATTCATAGTACCCCAAACTGTCATGACCATGAA
CGCAACCATAAAGTGCCTCCACCTATTAAACCTAAACCAGTTGTACCTAAGACAAATGTGAAAAAACTCGATCCAAACCTTTTAAAAACA
ATTGAAGCTGGTATTGGTAAAAATCCAAGAAAGCAGACTTCCCGGGTGCCTTTGGCACATCCTGAAGATATGGATCCTTCAGATAACTAT
GCGGAACCCATTGATACAATTTTCAAACAGAAGGGCTATTCTGATGAGATTTATGTTGTCCCAGATGATAGTCAAAATCGTATTAAAATT
CGAAACTCATTTGTAAATAACACCCAAGGAGATGAAGAAAATGGGTTTTCTGATAGAACCTCAAAAAGTCATGGGGAACGGAGGCCTTCA
AAATACAAATATAAATCTAAAACCTTGTTTAGTAAAGCCAAGTCATACTATAGAAGAACACATTCAGATGCCAGTGATGATGAGGCTTTC
ACCACTTCTAAAACAAAAAGAAAAGGAAGACATCGTGGAAGTGAAGAAGATCCACTTCTTTCTCCTGTTGAAACTTGGAAAGGTGGTATT
GATAATCCTGCAATCACTTCTGACCAGGAGTTAGATGATAAGAAGATGAAGAAGAAAACCCACAAAGTGAAAGAAGATAAAAAGCAGAAA
AAGAAAACTAAGAACTTCAATCCACCAACACGTAGAAATTGGGAAAGTAATTACTTTGGGATGCCCCTCCAGGATCTGGTTACAGCTGAG
AAGCCCATACCACTATTTGTTGAGAAATGTGTGGAATTTATTGAAGATACAGCGTATTCTCAGCTATGACACAGTGGTGCAAACAACTGG
AGACTCGTGGCACATACCATATGATGAAGACTTGGTAGAAAGATGTTCCTGTGAAGTACCAACCAAATGGCTTTGCCTCCACCAAAAGAC
ATAGAGATTCTTACCTCTATGCTAAGTTTGTGTTTGGGTACCCTCTAGGTTGGCATCAGAGGCTCTTGAGCTGGTGTTTGTTTAGGGCAT
TGCCTCTGTCCTGAAGATAAAAGGATTCTATTAACAGCATTGACATTGATTTTTTAATGAAATGAGATATATCTTTTCATAACCAGCTGC
GTTTTTTTCCCCTAACATTTGTTTTTGGAGGCTTATCAAGAGTTGGAGAACTTAGTGTAGAGCAAAACCTGCATTTCTCCTACTGGGCCA
GCTATTCCACTTAGCTTGGGTGACTAATAGTGCTTTTGGTATCCATTTTTTGCTACTTCTGACCTTGCCTTCCAGGCCTACCAATAGCAG
AATCAATCCATCTGTCCCTGAGATACTCATGTTGTTTCAAATGCCTCCTCCCATTTCTGGCATAGTCTCATTCTCTGTATGTTATGCCCT
ATCCACATGGAATCATTTATCGTCCTCTGTAATAAACTGGCCAAGATACTAAAGGCTTACTATTCATAGCAGTTTTTAATTACTTATCAT
CCAATTATTTGGATTGGAGAAGAGGGGGCATTCACTCCTCTTTTTCTTATTTTTTTTGGAAATAGAGTCTCAACTTACTCTGTCGCCAGG
GCTGGAGTGCAGTGACGTGATCACAGTTCACTGCAGCCTCAAACTCCCAGGCTCAAGCAATCTTCCTACCTCAGCCCTCCTGAGTAATTG
GGACTACAGAACAGAGAATGTCAGTATCCAATAGGATGCCAGTGGAATTCCCTGACGATTCCATCCATGCGGCTCTGCTGGAGCAGGGTA
GTGTCCTAGGCTGGGAGAATGGGATGGAGCCTCCACCTCATGAAGTAGCTTCCTTTGGAGGTGGCTATGGCAGGTCTTCGGAGAGAATAT
GCTTTTAAGGCTATTAACCAGGGTGGCCTTACATCAGTAGCTGTCAGAGGGAAAGACTGTGCAGTAATTGTCACACAGAAGAAAGTACCT
GACAAATTATTGGATTCCAGCACAGTGACTCACTTATTCAAGATAACTGAAAACATTGGTTGTGTGATGACCGGAATGACAGCTGACAGC
AGATCCCAGGTACAGAGGGCACGCTATGAGGCAGCTAACTGGAAATACAAGTATGGCTATGAGATTCCTGTGGACATGCTGTGTAAAAGA
ATTGCCGATATTTCTCAGGTCTACACACAGAATGCTGAAATGAGGCCTCTTGGTTGTTGTATGATTTTAATTGGTATAGATGAAGAGCAA
GGCCCTCAGGTATATAAGTGTGATCCTGCAGGTTACTACTGTGGGTTTAAAGCCACTGCAGCGGGAGTTAAACAAACTGAGTCAACCAGC
TTCCTTGAAAAAAAAGTGAAGAAGAAATTTGATTGGACATTTGAACAGACAGTGGAAACTGCAATTACATGCCTGTCTACTGTTCTATCA
ATTGATTTCAAACCTTCAGAAATAGAAGTTGGAGTAGTGACAGTTGAAAATCCTAAATTCAGGATTCTTACAGAAGCAGAGATTGATGCT
CACCTTGTTGCTCTAGCAGAGAGAGACTAAACATTGTCGTTAGTTTACCAGATCCGTGATGCCACTTACCTGTGTGTTTGGTAACAACAA
ACCAACATCATGGAGGTCCCTGGATTGAAAAAGGAGCCTCTCCCACTCCTCCTACCACCGAAGTGGTTAGGACTCTATATAAATAAAAAC

>6139_6139_7_ARHGAP5-KIAA0391_ARHGAP5_chr14_32586493_ENST00000539826_KIAA0391_chr14_35742641_ENST00000557565_length(amino acids)=1293AA_BP=
MMAKNKEPRPPSYTISIVGLSGTEKDKGNCGVGKSCLCNRFVRSKADEYYPEHTSVLSTIDFGGRVVNNDHFLYWGDIIQNSEDGVECKI
HVIEQTEFIDDQTFLPHRSTNLQPYIKRAAASKLQSAEKLMYICTDQLGLEQDFEQKQMPEGKLNVDGFLLCIDVSQGCNRKFDDQLKFV
NNLFVQLSKSKKPVIIAATKCDECVDHYLREVQAFASNKKNLLVVETSARFNVNIETCFTALVQMLDKTRSKPKIIPYLDAYKTQRQLVV
TATDKFEKLVQTVRDYHATWKTVSNKLKNHPDYEEYINLEGTRKARNTFSKHIEQLKQEHIRKRREEYINTLPRAFNTLLPNLEEIEHLN
WSEALKLMEKRADFQLCFVVLEKTPWDETDHIDKINDRRIPFDLLSTLEAEKVYQNHVQHLISEKRRVEMKEKFKKTLEKIQFISPGQPW
EEVMCFVMEDEAYKYITEADSKEVYGRHQREIVEKAKEEFQEMLFEHSELFYDLDLNATPSSDKMSEIHTVLSEEPRYKALQKLAPDRES
LLLKHIGFVYHPTKETCLSGQNCTDIKVEQLLASSLLQLDHGRLRLYHDSTNIDKVNLFILGKDGLAQELANEIRTQSTDDEYALDGKIY
ELDLRPVDAKSPYFLSQLWTAAFKPHGCFCVFNSIESLSFIGEFIGKIRTEASQIRKDKYMANLPFTLILANQRDSISKNLPILRHQGQQ
LANKLQCPFVDVPAGTYPRKFNETQIKQALRGVLESVKHNLDVVSPIPANKDLSEADLRIVMCAMCGDPFSVDLILSPFLDSHSCSAAQA
GQNNSLMLDKIIGEKRRRIQITILSYHSSIGVRKDELVHGYILVYSAKRKASMGMLRAFLSEVQDTIPVQLVAVTDSQADFFENEAIKEL
MTEGEHIATEITAKFTALYSLSQYHRQTEVFTLFFSDVLEKKNMIENSYLSDNTRESTHQSEDVFLPSPRDCFPYNNYPDSDDDTEAPPP
YSPIGDDVQLLPTPSDRSRYRLDLEGNEYPIHSTPNCHDHERNHKVPPPIKPKPVVPKTNVKKLDPNLLKTIEAGIGKNPRKQTSRVPLA
HPEDMDPSDNYAEPIDTIFKQKGYSDEIYVVPDDSQNRIKIRNSFVNNTQGDEENGFSDRTSKSHGERRPSKYKYKSKTLFSKAKSYYRR
THSDASDDEAFTTSKTKRKGRHRGSEEDPLLSPVETWKGGIDNPAITSDQELDDKKMKKKTHKVKEDKKQKKKTKNFNPPTRRNWESNYF

--------------------------------------------------------------
>6139_6139_8_ARHGAP5-KIAA0391_ARHGAP5_chr14_32586493_ENST00000539826_KIAA0391_chr14_35742641_ENST00000603544_length(transcript)=4338nt_BP=4102nt
CTGCGCCGCCGCGCCGCCGCTCCGCCCCCGGTCGGGTGTGTGGCTGCGCGCGCCGGGAGAGATGCTGAGGAAGATGATCCCTATGATCTT
GAAGATGTTTCTGCACAGAAATGAGGGAAATACAAAGAACCAAATACAGTTCTGAAATTTGGGATCTGTATTTTGAGATGATTTTATTTT
CAGAATGAGAAGCATATCTGGTTACCTTTATGAATGTAGAGACATGAGAAGAGAGTTATGATGGCAAAAAACAAAGAGCCTCGTCCCCCA
TCCTATACCATCAGTATAGTTGGACTCTCTGGGACTGAAAAAGACAAAGGTAACTGTGGAGTTGGAAAGTCTTGTTTGTGCAATAGATTT
GTACGCTCAAAAGCAGATGAATATTATCCAGAGCATACTTCTGTGCTTAGCACCATTGACTTTGGAGGACGAGTAGTAAACAATGATCAC
TTTTTGTACTGGGGTGACATAATACAAAATAGTGAAGATGGAGTAGAATGCAAAATTCATGTCATTGAACAAACAGAGTTCATTGATGAC
CAGACTTTCTTGCCTCATCGGAGTACGAATTTGCAACCATATATAAAACGTGCAGCTGCATCTAAATTGCAGTCAGCAGAAAAACTAATG
TACATTTGCACTGATCAGCTAGGCTTAGAACAAGACTTTGAACAGAAGCAAATGCCTGAAGGGAAGCTCAACGTAGATGGATTTTTATTA
TGCATTGATGTAAGTCAAGGATGCAATAGGAAGTTTGATGATCAACTTAAATTTGTGAATAACCTTTTTGTCCAGTTATCAAAATCAAAA
AAACCTGTAATAATAGCAGCAACTAAATGTGATGAATGCGTGGATCATTATCTTAGAGAAGTTCAGGCATTTGCTTCAAATAAAAAGAAC
CTTCTTGTAGTGGAAACATCAGCACGATTTAATGTCAACATTGAAACATGTTTTACTGCACTGGTACAAATGTTGGATAAAACTCGTAGC
AAGCCTAAAATTATTCCCTATTTGGATGCTTATAAAACACAGAGACAACTTGTTGTCACAGCAACAGATAAGTTTGAAAAACTTGTGCAG
ACTGTGAGAGATTATCATGCAACTTGGAAAACTGTTAGTAATAAATTAAAAAATCATCCTGATTATGAAGAATACATCAACTTAGAGGGA
ACAAGAAAGGCCAGAAATACATTCTCAAAACATATAGAACAACTTAAACAGGAACATATAAGAAAAAGGAGAGAAGAGTATATAAATACT
TTACCAAGAGCTTTTAACACTCTTTTGCCAAATCTAGAAGAGATTGAACATTTGAATTGGTCAGAAGCTTTGAAGTTAATGGAAAAGAGA
GCAGATTTCCAGTTATGTTTTGTGGTGCTAGAAAAAACTCCTTGGGATGAAACTGACCATATAGACAAAATTAATGATAGGCGGATTCCA
TTTGACCTCCTGAGCACTTTAGAAGCTGAAAAAGTCTATCAGAACCATGTACAGCATCTGATATCCGAGAAGAGGAGGGTGGAAATGAAG
GAAAAATTCAAAAAGACTTTGGAAAAAATTCAATTCATTTCACCAGGGCAGCCATGGGAGGAAGTTATGTGCTTTGTTATGGAGGATGAA
GCCTACAAATATATCACTGAGGCTGATAGCAAAGAGGTATATGGTAGGCATCAGCGAGAAATAGTTGAAAAAGCCAAAGAAGAGTTTCAA
GAAATGCTTTTTGAGCATTCTGAACTTTTTTATGATTTAGATCTTAATGCAACACCTAGTTCAGATAAAATGAGTGAAATTCATACAGTT
CTGAGTGAAGAACCTAGATATAAAGCTTTACAGAAACTTGCACCTGATAGGGAATCCCTTCTACTTAAGCATATAGGATTTGTTTATCAT
CCCACTAAAGAAACATGTCTTAGTGGCCAAAATTGTACAGACATTAAAGTGGAGCAGTTACTTGCTAGTAGTCTTTTACAGTTGGATCAT
GGCCGCTTAAGATTATATCACGATAGTACCAATATAGATAAAGTTAACCTTTTTATTTTAGGGAAGGATGGCCTTGCCCAAGAACTAGCA
AATGAGATAAGGACACAATCCACTGATGATGAGTATGCCTTAGATGGAAAAATTTATGAACTTGATCTTCGGCCGGTTGATGCCAAATCG
CCTTACTTTTTGAGTCAGTTATGGACTGCCGCCTTTAAACCACATGGGTGCTTCTGTGTATTTAATTCCATTGAGTCATTGAGTTTTATT
GGGGAATTTATTGGGAAAATAAGAACTGAAGCTTCTCAGATCAGAAAAGATAAATACATGGCTAATCTTCCATTTACATTAATTCTGGCT
AATCAGAGAGATTCCATTAGTAAGAATCTACCAATTCTCAGGCACCAAGGGCAGCAGTTGGCAAACAAGTTGCAATGTCCTTTTGTAGAT
GTACCTGCTGGTACATATCCTCGTAAATTTAATGAAACCCAAATAAAGCAAGCTCTCAGAGGAGTATTGGAATCAGTTAAACACAATTTG
GATGTGGTGAGCCCAATTCCTGCCAATAAGGACTTATCAGAAGCTGACTTGAGAATTGTCATGTGCGCCATGTGTGGAGATCCATTTAGT
GTGGATCTTATTCTTTCACCCTTCCTTGATTCTCATTCTTGCAGTGCTGCTCAAGCTGGACAGAATAATTCCCTAATGCTTGATAAAATC
ATTGGTGAAAAAAGGAGGCGAATACAGATCACAATATTATCATACCACTCTTCAATTGGAGTAAGAAAAGATGAACTAGTTCATGGGTAT
ATATTAGTTTACTCTGCAAAACGGAAAGCTTCGATGGGAATGCTTCGAGCATTTCTATCAGAAGTTCAAGACACCATTCCTGTACAGCTG
GTGGCAGTTACTGACAGCCAAGCAGATTTTTTTGAAAATGAGGCTATCAAAGAGTTAATGACTGAAGGAGAACACATTGCAACTGAGATC
ACTGCTAAATTTACAGCACTGTATTCTTTATCTCAGTATCATCGGCAAACTGAGGTCTTTACTCTGTTTTTTAGTGATGTTCTAGAGAAA
AAAAATATGATAGAAAATTCTTATTTGTCTGATAATACAAGGGAATCAACCCATCAAAGTGAAGATGTTTTTCTACCATCTCCCAGAGAC
TGTTTTCCCTATAATAACTACCCTGATTCAGATGATGACACAGAAGCACCACCTCCTTATAGTCCAATTGGGGATGATGTACAGTTGCTT
CCAACACCTAGTGACCGTTCCAGATATAGATTAGATTTGGAAGGAAATGAGTATCCTATTCATAGTACCCCAAACTGTCATGACCATGAA
CGCAACCATAAAGTGCCTCCACCTATTAAACCTAAACCAGTTGTACCTAAGACAAATGTGAAAAAACTCGATCCAAACCTTTTAAAAACA
ATTGAAGCTGGTATTGGTAAAAATCCAAGAAAGCAGACTTCCCGGGTGCCTTTGGCACATCCTGAAGATATGGATCCTTCAGATAACTAT
GCGGAACCCATTGATACAATTTTCAAACAGAAGGGCTATTCTGATGAGATTTATGTTGTCCCAGATGATAGTCAAAATCGTATTAAAATT
CGAAACTCATTTGTAAATAACACCCAAGGAGATGAAGAAAATGGGTTTTCTGATAGAACCTCAAAAAGTCATGGGGAACGGAGGCCTTCA
AAATACAAATATAAATCTAAAACCTTGTTTAGTAAAGCCAAGTCATACTATAGAAGAACACATTCAGATGCCAGTGATGATGAGGCTTTC
ACCACTTCTAAAACAAAAAGAAAAGGAAGACATCGTGGAAGTGAAGAAGATCCACTTCTTTCTCCTGTTGAAACTTGGAAAGGTGGTATT
GATAATCCTGCAATCACTTCTGACCAGGAGTTAGATGATAAGAAGATGAAGAAGAAAACCCACAAAGTGAAAGAAGATAAAAAGCAGAAA
AAGAAAACTAAGAACTTCAATCCACCAACACGTAGAAATTGGGAAAGTAATTACTTTGGGATGCCCCTCCAGGATCTGGTTACAGCTGAG
AAGCCCATACCACTATTTGTTGAGAAATGTGTGGAATTTATTGAAGATACAGCGTATTCTCAGCTATGACACAGTGGTGCAAACAACTGG
AGACTCGTGGCACATACCATATGATGAAGACTTGGTAGAAAGATGTTCCTGTGAAGTACCAACCAAATGGCTTTGCCTCCACCAAAAGAC
ATAGAGATTCTTACCTCTATGCTAAGTTTGTGTTTGGGTACCCTCTAGGTTGGCATCAGAGGCTCTTGAGCTGGTGTTTGTTTAGGGCAT

>6139_6139_8_ARHGAP5-KIAA0391_ARHGAP5_chr14_32586493_ENST00000539826_KIAA0391_chr14_35742641_ENST00000603544_length(amino acids)=1293AA_BP=
MMAKNKEPRPPSYTISIVGLSGTEKDKGNCGVGKSCLCNRFVRSKADEYYPEHTSVLSTIDFGGRVVNNDHFLYWGDIIQNSEDGVECKI
HVIEQTEFIDDQTFLPHRSTNLQPYIKRAAASKLQSAEKLMYICTDQLGLEQDFEQKQMPEGKLNVDGFLLCIDVSQGCNRKFDDQLKFV
NNLFVQLSKSKKPVIIAATKCDECVDHYLREVQAFASNKKNLLVVETSARFNVNIETCFTALVQMLDKTRSKPKIIPYLDAYKTQRQLVV
TATDKFEKLVQTVRDYHATWKTVSNKLKNHPDYEEYINLEGTRKARNTFSKHIEQLKQEHIRKRREEYINTLPRAFNTLLPNLEEIEHLN
WSEALKLMEKRADFQLCFVVLEKTPWDETDHIDKINDRRIPFDLLSTLEAEKVYQNHVQHLISEKRRVEMKEKFKKTLEKIQFISPGQPW
EEVMCFVMEDEAYKYITEADSKEVYGRHQREIVEKAKEEFQEMLFEHSELFYDLDLNATPSSDKMSEIHTVLSEEPRYKALQKLAPDRES
LLLKHIGFVYHPTKETCLSGQNCTDIKVEQLLASSLLQLDHGRLRLYHDSTNIDKVNLFILGKDGLAQELANEIRTQSTDDEYALDGKIY
ELDLRPVDAKSPYFLSQLWTAAFKPHGCFCVFNSIESLSFIGEFIGKIRTEASQIRKDKYMANLPFTLILANQRDSISKNLPILRHQGQQ
LANKLQCPFVDVPAGTYPRKFNETQIKQALRGVLESVKHNLDVVSPIPANKDLSEADLRIVMCAMCGDPFSVDLILSPFLDSHSCSAAQA
GQNNSLMLDKIIGEKRRRIQITILSYHSSIGVRKDELVHGYILVYSAKRKASMGMLRAFLSEVQDTIPVQLVAVTDSQADFFENEAIKEL
MTEGEHIATEITAKFTALYSLSQYHRQTEVFTLFFSDVLEKKNMIENSYLSDNTRESTHQSEDVFLPSPRDCFPYNNYPDSDDDTEAPPP
YSPIGDDVQLLPTPSDRSRYRLDLEGNEYPIHSTPNCHDHERNHKVPPPIKPKPVVPKTNVKKLDPNLLKTIEAGIGKNPRKQTSRVPLA
HPEDMDPSDNYAEPIDTIFKQKGYSDEIYVVPDDSQNRIKIRNSFVNNTQGDEENGFSDRTSKSHGERRPSKYKYKSKTLFSKAKSYYRR
THSDASDDEAFTTSKTKRKGRHRGSEEDPLLSPVETWKGGIDNPAITSDQELDDKKMKKKTHKVKEDKKQKKKTKNFNPPTRRNWESNYF

--------------------------------------------------------------
>6139_6139_9_ARHGAP5-KIAA0391_ARHGAP5_chr14_32586493_ENST00000556611_KIAA0391_chr14_35742641_ENST00000557565_length(transcript)=5973nt_BP=4117nt
GCGCGCGTCCCGTCCAGGCTGCGCCGCCGCGCCGCCGCTCCGCCCCCGGTCGGGTGTGTGGCTGCGCGCGCCGGGAGAGATGCTGAGGAA
GATGATCCCTATGATCTTGAAGATGTTTCTGCACAGAAATGAGGGAAATACAAAGAACCAAATACAGTTCTGAAATTTGGGATCTGTATT
TTGAGATGATTTTATTTTCAGAATGAGAAGCATATCTGGTTACCTTTATGAATGTAGAGACATGAGAAGAGAGTTATGATGGCAAAAAAC
AAAGAGCCTCGTCCCCCATCCTATACCATCAGTATAGTTGGACTCTCTGGGACTGAAAAAGACAAAGGTAACTGTGGAGTTGGAAAGTCT
TGTTTGTGCAATAGATTTGTACGCTCAAAAGCAGATGAATATTATCCAGAGCATACTTCTGTGCTTAGCACCATTGACTTTGGAGGACGA
GTAGTAAACAATGATCACTTTTTGTACTGGGGTGACATAATACAAAATAGTGAAGATGGAGTAGAATGCAAAATTCATGTCATTGAACAA
ACAGAGTTCATTGATGACCAGACTTTCTTGCCTCATCGGAGTACGAATTTGCAACCATATATAAAACGTGCAGCTGCATCTAAATTGCAG
TCAGCAGAAAAACTAATGTACATTTGCACTGATCAGCTAGGCTTAGAACAAGACTTTGAACAGAAGCAAATGCCTGAAGGGAAGCTCAAC
GTAGATGGATTTTTATTATGCATTGATGTAAGTCAAGGATGCAATAGGAAGTTTGATGATCAACTTAAATTTGTGAATAACCTTTTTGTC
CAGTTATCAAAATCAAAAAAACCTGTAATAATAGCAGCAACTAAATGTGATGAATGCGTGGATCATTATCTTAGAGAAGTTCAGGCATTT
GCTTCAAATAAAAAGAACCTTCTTGTAGTGGAAACATCAGCACGATTTAATGTCAACATTGAAACATGTTTTACTGCACTGGTACAAATG
TTGGATAAAACTCGTAGCAAGCCTAAAATTATTCCCTATTTGGATGCTTATAAAACACAGAGACAACTTGTTGTCACAGCAACAGATAAG
TTTGAAAAACTTGTGCAGACTGTGAGAGATTATCATGCAACTTGGAAAACTGTTAGTAATAAATTAAAAAATCATCCTGATTATGAAGAA
TACATCAACTTAGAGGGAACAAGAAAGGCCAGAAATACATTCTCAAAACATATAGAACAACTTAAACAGGAACATATAAGAAAAAGGAGA
GAAGAGTATATAAATACTTTACCAAGAGCTTTTAACACTCTTTTGCCAAATCTAGAAGAGATTGAACATTTGAATTGGTCAGAAGCTTTG
AAGTTAATGGAAAAGAGAGCAGATTTCCAGTTATGTTTTGTGGTGCTAGAAAAAACTCCTTGGGATGAAACTGACCATATAGACAAAATT
AATGATAGGCGGATTCCATTTGACCTCCTGAGCACTTTAGAAGCTGAAAAAGTCTATCAGAACCATGTACAGCATCTGATATCCGAGAAG
AGGAGGGTGGAAATGAAGGAAAAATTCAAAAAGACTTTGGAAAAAATTCAATTCATTTCACCAGGGCAGCCATGGGAGGAAGTTATGTGC
TTTGTTATGGAGGATGAAGCCTACAAATATATCACTGAGGCTGATAGCAAAGAGGTATATGGTAGGCATCAGCGAGAAATAGTTGAAAAA
GCCAAAGAAGAGTTTCAAGAAATGCTTTTTGAGCATTCTGAACTTTTTTATGATTTAGATCTTAATGCAACACCTAGTTCAGATAAAATG
AGTGAAATTCATACAGTTCTGAGTGAAGAACCTAGATATAAAGCTTTACAGAAACTTGCACCTGATAGGGAATCCCTTCTACTTAAGCAT
ATAGGATTTGTTTATCATCCCACTAAAGAAACATGTCTTAGTGGCCAAAATTGTACAGACATTAAAGTGGAGCAGTTACTTGCTAGTAGT
CTTTTACAGTTGGATCATGGCCGCTTAAGATTATATCACGATAGTACCAATATAGATAAAGTTAACCTTTTTATTTTAGGGAAGGATGGC
CTTGCCCAAGAACTAGCAAATGAGATAAGGACACAATCCACTGATGATGAGTATGCCTTAGATGGAAAAATTTATGAACTTGATCTTCGG
CCGGTTGATGCCAAATCGCCTTACTTTTTGAGTCAGTTATGGACTGCCGCCTTTAAACCACATGGGTGCTTCTGTGTATTTAATTCCATT
GAGTCATTGAGTTTTATTGGGGAATTTATTGGGAAAATAAGAACTGAAGCTTCTCAGATCAGAAAAGATAAATACATGGCTAATCTTCCA
TTTACATTAATTCTGGCTAATCAGAGAGATTCCATTAGTAAGAATCTACCAATTCTCAGGCACCAAGGGCAGCAGTTGGCAAACAAGTTG
CAATGTCCTTTTGTAGATGTACCTGCTGGTACATATCCTCGTAAATTTAATGAAACCCAAATAAAGCAAGCTCTCAGAGGAGTATTGGAA
TCAGTTAAACACAATTTGGATGTGGTGAGCCCAATTCCTGCCAATAAGGACTTATCAGAAGCTGACTTGAGAATTGTCATGTGCGCCATG
TGTGGAGATCCATTTAGTGTGGATCTTATTCTTTCACCCTTCCTTGATTCTCATTCTTGCAGTGCTGCTCAAGCTGGACAGAATAATTCC
CTAATGCTTGATAAAATCATTGGTGAAAAAAGGAGGCGAATACAGATCACAATATTATCATACCACTCTTCAATTGGAGTAAGAAAAGAT
GAACTAGTTCATGGGTATATATTAGTTTACTCTGCAAAACGGAAAGCTTCGATGGGAATGCTTCGAGCATTTCTATCAGAAGTTCAAGAC
ACCATTCCTGTACAGCTGGTGGCAGTTACTGACAGCCAAGCAGATTTTTTTGAAAATGAGGCTATCAAAGAGTTAATGACTGAAGGAGAA
CACATTGCAACTGAGATCACTGCTAAATTTACAGCACTGTATTCTTTATCTCAGTATCATCGGCAAACTGAGGTCTTTACTCTGTTTTTT
AGTGATGTTCTAGAGAAAAAAAATATGATAGAAAATTCTTATTTGTCTGATAATACAAGGGAATCAACCCATCAAAGTGAAGATGTTTTT
CTACCATCTCCCAGAGACTGTTTTCCCTATAATAACTACCCTGATTCAGATGATGACACAGAAGCACCACCTCCTTATAGTCCAATTGGG
GATGATGTACAGTTGCTTCCAACACCTAGTGACCGTTCCAGATATAGATTAGATTTGGAAGGAAATGAGTATCCTATTCATAGTACCCCA
AACTGTCATGACCATGAACGCAACCATAAAGTGCCTCCACCTATTAAACCTAAACCAGTTGTACCTAAGACAAATGTGAAAAAACTCGAT
CCAAACCTTTTAAAAACAATTGAAGCTGGTATTGGTAAAAATCCAAGAAAGCAGACTTCCCGGGTGCCTTTGGCACATCCTGAAGATATG
GATCCTTCAGATAACTATGCGGAACCCATTGATACAATTTTCAAACAGAAGGGCTATTCTGATGAGATTTATGTTGTCCCAGATGATAGT
CAAAATCGTATTAAAATTCGAAACTCATTTGTAAATAACACCCAAGGAGATGAAGAAAATGGGTTTTCTGATAGAACCTCAAAAAGTCAT
GGGGAACGGAGGCCTTCAAAATACAAATATAAATCTAAAACCTTGTTTAGTAAAGCCAAGTCATACTATAGAAGAACACATTCAGATGCC
AGTGATGATGAGGCTTTCACCACTTCTAAAACAAAAAGAAAAGGAAGACATCGTGGAAGTGAAGAAGATCCACTTCTTTCTCCTGTTGAA
ACTTGGAAAGGTGGTATTGATAATCCTGCAATCACTTCTGACCAGGAGTTAGATGATAAGAAGATGAAGAAGAAAACCCACAAAGTGAAA
GAAGATAAAAAGAAAAAGAAAACTAAGAACTTCAATCCACCAACACGTAGAAATTGGGAAAGTAATTACTTTGGGATGCCCCTCCAGGAT
CTGGTTACAGCTGAGAAGCCCATACCACTATTTGTTGAGAAATGTGTGGAATTTATTGAAGATACAGCGTATTCTCAGCTATGACACAGT
GGTGCAAACAACTGGAGACTCGTGGCACATACCATATGATGAAGACTTGGTAGAAAGATGTTCCTGTGAAGTACCAACCAAATGGCTTTG
CCTCCACCAAAAGACATAGAGATTCTTACCTCTATGCTAAGTTTGTGTTTGGGTACCCTCTAGGTTGGCATCAGAGGCTCTTGAGCTGGT
GTTTGTTTAGGGCATTGCCTCTGTCCTGAAGATAAAAGGATTCTATTAACAGCATTGACATTGATTTTTTAATGAAATGAGATATATCTT
TTCATAACCAGCTGCGTTTTTTTCCCCTAACATTTGTTTTTGGAGGCTTATCAAGAGTTGGAGAACTTAGTGTAGAGCAAAACCTGCATT
TCTCCTACTGGGCCAGCTATTCCACTTAGCTTGGGTGACTAATAGTGCTTTTGGTATCCATTTTTTGCTACTTCTGACCTTGCCTTCCAG
GCCTACCAATAGCAGAATCAATCCATCTGTCCCTGAGATACTCATGTTGTTTCAAATGCCTCCTCCCATTTCTGGCATAGTCTCATTCTC
TGTATGTTATGCCCTATCCACATGGAATCATTTATCGTCCTCTGTAATAAACTGGCCAAGATACTAAAGGCTTACTATTCATAGCAGTTT
TTAATTACTTATCATCCAATTATTTGGATTGGAGAAGAGGGGGCATTCACTCCTCTTTTTCTTATTTTTTTTGGAAATAGAGTCTCAACT
TACTCTGTCGCCAGGGCTGGAGTGCAGTGACGTGATCACAGTTCACTGCAGCCTCAAACTCCCAGGCTCAAGCAATCTTCCTACCTCAGC
CCTCCTGAGTAATTGGGACTACAGAACAGAGAATGTCAGTATCCAATAGGATGCCAGTGGAATTCCCTGACGATTCCATCCATGCGGCTC
TGCTGGAGCAGGGTAGTGTCCTAGGCTGGGAGAATGGGATGGAGCCTCCACCTCATGAAGTAGCTTCCTTTGGAGGTGGCTATGGCAGGT
CTTCGGAGAGAATATGCTTTTAAGGCTATTAACCAGGGTGGCCTTACATCAGTAGCTGTCAGAGGGAAAGACTGTGCAGTAATTGTCACA
CAGAAGAAAGTACCTGACAAATTATTGGATTCCAGCACAGTGACTCACTTATTCAAGATAACTGAAAACATTGGTTGTGTGATGACCGGA
ATGACAGCTGACAGCAGATCCCAGGTACAGAGGGCACGCTATGAGGCAGCTAACTGGAAATACAAGTATGGCTATGAGATTCCTGTGGAC
ATGCTGTGTAAAAGAATTGCCGATATTTCTCAGGTCTACACACAGAATGCTGAAATGAGGCCTCTTGGTTGTTGTATGATTTTAATTGGT
ATAGATGAAGAGCAAGGCCCTCAGGTATATAAGTGTGATCCTGCAGGTTACTACTGTGGGTTTAAAGCCACTGCAGCGGGAGTTAAACAA
ACTGAGTCAACCAGCTTCCTTGAAAAAAAAGTGAAGAAGAAATTTGATTGGACATTTGAACAGACAGTGGAAACTGCAATTACATGCCTG
TCTACTGTTCTATCAATTGATTTCAAACCTTCAGAAATAGAAGTTGGAGTAGTGACAGTTGAAAATCCTAAATTCAGGATTCTTACAGAA
GCAGAGATTGATGCTCACCTTGTTGCTCTAGCAGAGAGAGACTAAACATTGTCGTTAGTTTACCAGATCCGTGATGCCACTTACCTGTGT
GTTTGGTAACAACAAACCAACATCATGGAGGTCCCTGGATTGAAAAAGGAGCCTCTCCCACTCCTCCTACCACCGAAGTGGTTAGGACTC

>6139_6139_9_ARHGAP5-KIAA0391_ARHGAP5_chr14_32586493_ENST00000556611_KIAA0391_chr14_35742641_ENST00000557565_length(amino acids)=1292AA_BP=
MMAKNKEPRPPSYTISIVGLSGTEKDKGNCGVGKSCLCNRFVRSKADEYYPEHTSVLSTIDFGGRVVNNDHFLYWGDIIQNSEDGVECKI
HVIEQTEFIDDQTFLPHRSTNLQPYIKRAAASKLQSAEKLMYICTDQLGLEQDFEQKQMPEGKLNVDGFLLCIDVSQGCNRKFDDQLKFV
NNLFVQLSKSKKPVIIAATKCDECVDHYLREVQAFASNKKNLLVVETSARFNVNIETCFTALVQMLDKTRSKPKIIPYLDAYKTQRQLVV
TATDKFEKLVQTVRDYHATWKTVSNKLKNHPDYEEYINLEGTRKARNTFSKHIEQLKQEHIRKRREEYINTLPRAFNTLLPNLEEIEHLN
WSEALKLMEKRADFQLCFVVLEKTPWDETDHIDKINDRRIPFDLLSTLEAEKVYQNHVQHLISEKRRVEMKEKFKKTLEKIQFISPGQPW
EEVMCFVMEDEAYKYITEADSKEVYGRHQREIVEKAKEEFQEMLFEHSELFYDLDLNATPSSDKMSEIHTVLSEEPRYKALQKLAPDRES
LLLKHIGFVYHPTKETCLSGQNCTDIKVEQLLASSLLQLDHGRLRLYHDSTNIDKVNLFILGKDGLAQELANEIRTQSTDDEYALDGKIY
ELDLRPVDAKSPYFLSQLWTAAFKPHGCFCVFNSIESLSFIGEFIGKIRTEASQIRKDKYMANLPFTLILANQRDSISKNLPILRHQGQQ
LANKLQCPFVDVPAGTYPRKFNETQIKQALRGVLESVKHNLDVVSPIPANKDLSEADLRIVMCAMCGDPFSVDLILSPFLDSHSCSAAQA
GQNNSLMLDKIIGEKRRRIQITILSYHSSIGVRKDELVHGYILVYSAKRKASMGMLRAFLSEVQDTIPVQLVAVTDSQADFFENEAIKEL
MTEGEHIATEITAKFTALYSLSQYHRQTEVFTLFFSDVLEKKNMIENSYLSDNTRESTHQSEDVFLPSPRDCFPYNNYPDSDDDTEAPPP
YSPIGDDVQLLPTPSDRSRYRLDLEGNEYPIHSTPNCHDHERNHKVPPPIKPKPVVPKTNVKKLDPNLLKTIEAGIGKNPRKQTSRVPLA
HPEDMDPSDNYAEPIDTIFKQKGYSDEIYVVPDDSQNRIKIRNSFVNNTQGDEENGFSDRTSKSHGERRPSKYKYKSKTLFSKAKSYYRR
THSDASDDEAFTTSKTKRKGRHRGSEEDPLLSPVETWKGGIDNPAITSDQELDDKKMKKKTHKVKEDKKKKKTKNFNPPTRRNWESNYFG

--------------------------------------------------------------
>6139_6139_10_ARHGAP5-KIAA0391_ARHGAP5_chr14_32586493_ENST00000556611_KIAA0391_chr14_35742641_ENST00000603544_length(transcript)=4353nt_BP=4117nt
GCGCGCGTCCCGTCCAGGCTGCGCCGCCGCGCCGCCGCTCCGCCCCCGGTCGGGTGTGTGGCTGCGCGCGCCGGGAGAGATGCTGAGGAA
GATGATCCCTATGATCTTGAAGATGTTTCTGCACAGAAATGAGGGAAATACAAAGAACCAAATACAGTTCTGAAATTTGGGATCTGTATT
TTGAGATGATTTTATTTTCAGAATGAGAAGCATATCTGGTTACCTTTATGAATGTAGAGACATGAGAAGAGAGTTATGATGGCAAAAAAC
AAAGAGCCTCGTCCCCCATCCTATACCATCAGTATAGTTGGACTCTCTGGGACTGAAAAAGACAAAGGTAACTGTGGAGTTGGAAAGTCT
TGTTTGTGCAATAGATTTGTACGCTCAAAAGCAGATGAATATTATCCAGAGCATACTTCTGTGCTTAGCACCATTGACTTTGGAGGACGA
GTAGTAAACAATGATCACTTTTTGTACTGGGGTGACATAATACAAAATAGTGAAGATGGAGTAGAATGCAAAATTCATGTCATTGAACAA
ACAGAGTTCATTGATGACCAGACTTTCTTGCCTCATCGGAGTACGAATTTGCAACCATATATAAAACGTGCAGCTGCATCTAAATTGCAG
TCAGCAGAAAAACTAATGTACATTTGCACTGATCAGCTAGGCTTAGAACAAGACTTTGAACAGAAGCAAATGCCTGAAGGGAAGCTCAAC
GTAGATGGATTTTTATTATGCATTGATGTAAGTCAAGGATGCAATAGGAAGTTTGATGATCAACTTAAATTTGTGAATAACCTTTTTGTC
CAGTTATCAAAATCAAAAAAACCTGTAATAATAGCAGCAACTAAATGTGATGAATGCGTGGATCATTATCTTAGAGAAGTTCAGGCATTT
GCTTCAAATAAAAAGAACCTTCTTGTAGTGGAAACATCAGCACGATTTAATGTCAACATTGAAACATGTTTTACTGCACTGGTACAAATG
TTGGATAAAACTCGTAGCAAGCCTAAAATTATTCCCTATTTGGATGCTTATAAAACACAGAGACAACTTGTTGTCACAGCAACAGATAAG
TTTGAAAAACTTGTGCAGACTGTGAGAGATTATCATGCAACTTGGAAAACTGTTAGTAATAAATTAAAAAATCATCCTGATTATGAAGAA
TACATCAACTTAGAGGGAACAAGAAAGGCCAGAAATACATTCTCAAAACATATAGAACAACTTAAACAGGAACATATAAGAAAAAGGAGA
GAAGAGTATATAAATACTTTACCAAGAGCTTTTAACACTCTTTTGCCAAATCTAGAAGAGATTGAACATTTGAATTGGTCAGAAGCTTTG
AAGTTAATGGAAAAGAGAGCAGATTTCCAGTTATGTTTTGTGGTGCTAGAAAAAACTCCTTGGGATGAAACTGACCATATAGACAAAATT
AATGATAGGCGGATTCCATTTGACCTCCTGAGCACTTTAGAAGCTGAAAAAGTCTATCAGAACCATGTACAGCATCTGATATCCGAGAAG
AGGAGGGTGGAAATGAAGGAAAAATTCAAAAAGACTTTGGAAAAAATTCAATTCATTTCACCAGGGCAGCCATGGGAGGAAGTTATGTGC
TTTGTTATGGAGGATGAAGCCTACAAATATATCACTGAGGCTGATAGCAAAGAGGTATATGGTAGGCATCAGCGAGAAATAGTTGAAAAA
GCCAAAGAAGAGTTTCAAGAAATGCTTTTTGAGCATTCTGAACTTTTTTATGATTTAGATCTTAATGCAACACCTAGTTCAGATAAAATG
AGTGAAATTCATACAGTTCTGAGTGAAGAACCTAGATATAAAGCTTTACAGAAACTTGCACCTGATAGGGAATCCCTTCTACTTAAGCAT
ATAGGATTTGTTTATCATCCCACTAAAGAAACATGTCTTAGTGGCCAAAATTGTACAGACATTAAAGTGGAGCAGTTACTTGCTAGTAGT
CTTTTACAGTTGGATCATGGCCGCTTAAGATTATATCACGATAGTACCAATATAGATAAAGTTAACCTTTTTATTTTAGGGAAGGATGGC
CTTGCCCAAGAACTAGCAAATGAGATAAGGACACAATCCACTGATGATGAGTATGCCTTAGATGGAAAAATTTATGAACTTGATCTTCGG
CCGGTTGATGCCAAATCGCCTTACTTTTTGAGTCAGTTATGGACTGCCGCCTTTAAACCACATGGGTGCTTCTGTGTATTTAATTCCATT
GAGTCATTGAGTTTTATTGGGGAATTTATTGGGAAAATAAGAACTGAAGCTTCTCAGATCAGAAAAGATAAATACATGGCTAATCTTCCA
TTTACATTAATTCTGGCTAATCAGAGAGATTCCATTAGTAAGAATCTACCAATTCTCAGGCACCAAGGGCAGCAGTTGGCAAACAAGTTG
CAATGTCCTTTTGTAGATGTACCTGCTGGTACATATCCTCGTAAATTTAATGAAACCCAAATAAAGCAAGCTCTCAGAGGAGTATTGGAA
TCAGTTAAACACAATTTGGATGTGGTGAGCCCAATTCCTGCCAATAAGGACTTATCAGAAGCTGACTTGAGAATTGTCATGTGCGCCATG
TGTGGAGATCCATTTAGTGTGGATCTTATTCTTTCACCCTTCCTTGATTCTCATTCTTGCAGTGCTGCTCAAGCTGGACAGAATAATTCC
CTAATGCTTGATAAAATCATTGGTGAAAAAAGGAGGCGAATACAGATCACAATATTATCATACCACTCTTCAATTGGAGTAAGAAAAGAT
GAACTAGTTCATGGGTATATATTAGTTTACTCTGCAAAACGGAAAGCTTCGATGGGAATGCTTCGAGCATTTCTATCAGAAGTTCAAGAC
ACCATTCCTGTACAGCTGGTGGCAGTTACTGACAGCCAAGCAGATTTTTTTGAAAATGAGGCTATCAAAGAGTTAATGACTGAAGGAGAA
CACATTGCAACTGAGATCACTGCTAAATTTACAGCACTGTATTCTTTATCTCAGTATCATCGGCAAACTGAGGTCTTTACTCTGTTTTTT
AGTGATGTTCTAGAGAAAAAAAATATGATAGAAAATTCTTATTTGTCTGATAATACAAGGGAATCAACCCATCAAAGTGAAGATGTTTTT
CTACCATCTCCCAGAGACTGTTTTCCCTATAATAACTACCCTGATTCAGATGATGACACAGAAGCACCACCTCCTTATAGTCCAATTGGG
GATGATGTACAGTTGCTTCCAACACCTAGTGACCGTTCCAGATATAGATTAGATTTGGAAGGAAATGAGTATCCTATTCATAGTACCCCA
AACTGTCATGACCATGAACGCAACCATAAAGTGCCTCCACCTATTAAACCTAAACCAGTTGTACCTAAGACAAATGTGAAAAAACTCGAT
CCAAACCTTTTAAAAACAATTGAAGCTGGTATTGGTAAAAATCCAAGAAAGCAGACTTCCCGGGTGCCTTTGGCACATCCTGAAGATATG
GATCCTTCAGATAACTATGCGGAACCCATTGATACAATTTTCAAACAGAAGGGCTATTCTGATGAGATTTATGTTGTCCCAGATGATAGT
CAAAATCGTATTAAAATTCGAAACTCATTTGTAAATAACACCCAAGGAGATGAAGAAAATGGGTTTTCTGATAGAACCTCAAAAAGTCAT
GGGGAACGGAGGCCTTCAAAATACAAATATAAATCTAAAACCTTGTTTAGTAAAGCCAAGTCATACTATAGAAGAACACATTCAGATGCC
AGTGATGATGAGGCTTTCACCACTTCTAAAACAAAAAGAAAAGGAAGACATCGTGGAAGTGAAGAAGATCCACTTCTTTCTCCTGTTGAA
ACTTGGAAAGGTGGTATTGATAATCCTGCAATCACTTCTGACCAGGAGTTAGATGATAAGAAGATGAAGAAGAAAACCCACAAAGTGAAA
GAAGATAAAAAGAAAAAGAAAACTAAGAACTTCAATCCACCAACACGTAGAAATTGGGAAAGTAATTACTTTGGGATGCCCCTCCAGGAT
CTGGTTACAGCTGAGAAGCCCATACCACTATTTGTTGAGAAATGTGTGGAATTTATTGAAGATACAGCGTATTCTCAGCTATGACACAGT
GGTGCAAACAACTGGAGACTCGTGGCACATACCATATGATGAAGACTTGGTAGAAAGATGTTCCTGTGAAGTACCAACCAAATGGCTTTG
CCTCCACCAAAAGACATAGAGATTCTTACCTCTATGCTAAGTTTGTGTTTGGGTACCCTCTAGGTTGGCATCAGAGGCTCTTGAGCTGGT

>6139_6139_10_ARHGAP5-KIAA0391_ARHGAP5_chr14_32586493_ENST00000556611_KIAA0391_chr14_35742641_ENST00000603544_length(amino acids)=1292AA_BP=
MMAKNKEPRPPSYTISIVGLSGTEKDKGNCGVGKSCLCNRFVRSKADEYYPEHTSVLSTIDFGGRVVNNDHFLYWGDIIQNSEDGVECKI
HVIEQTEFIDDQTFLPHRSTNLQPYIKRAAASKLQSAEKLMYICTDQLGLEQDFEQKQMPEGKLNVDGFLLCIDVSQGCNRKFDDQLKFV
NNLFVQLSKSKKPVIIAATKCDECVDHYLREVQAFASNKKNLLVVETSARFNVNIETCFTALVQMLDKTRSKPKIIPYLDAYKTQRQLVV
TATDKFEKLVQTVRDYHATWKTVSNKLKNHPDYEEYINLEGTRKARNTFSKHIEQLKQEHIRKRREEYINTLPRAFNTLLPNLEEIEHLN
WSEALKLMEKRADFQLCFVVLEKTPWDETDHIDKINDRRIPFDLLSTLEAEKVYQNHVQHLISEKRRVEMKEKFKKTLEKIQFISPGQPW
EEVMCFVMEDEAYKYITEADSKEVYGRHQREIVEKAKEEFQEMLFEHSELFYDLDLNATPSSDKMSEIHTVLSEEPRYKALQKLAPDRES
LLLKHIGFVYHPTKETCLSGQNCTDIKVEQLLASSLLQLDHGRLRLYHDSTNIDKVNLFILGKDGLAQELANEIRTQSTDDEYALDGKIY
ELDLRPVDAKSPYFLSQLWTAAFKPHGCFCVFNSIESLSFIGEFIGKIRTEASQIRKDKYMANLPFTLILANQRDSISKNLPILRHQGQQ
LANKLQCPFVDVPAGTYPRKFNETQIKQALRGVLESVKHNLDVVSPIPANKDLSEADLRIVMCAMCGDPFSVDLILSPFLDSHSCSAAQA
GQNNSLMLDKIIGEKRRRIQITILSYHSSIGVRKDELVHGYILVYSAKRKASMGMLRAFLSEVQDTIPVQLVAVTDSQADFFENEAIKEL
MTEGEHIATEITAKFTALYSLSQYHRQTEVFTLFFSDVLEKKNMIENSYLSDNTRESTHQSEDVFLPSPRDCFPYNNYPDSDDDTEAPPP
YSPIGDDVQLLPTPSDRSRYRLDLEGNEYPIHSTPNCHDHERNHKVPPPIKPKPVVPKTNVKKLDPNLLKTIEAGIGKNPRKQTSRVPLA
HPEDMDPSDNYAEPIDTIFKQKGYSDEIYVVPDDSQNRIKIRNSFVNNTQGDEENGFSDRTSKSHGERRPSKYKYKSKTLFSKAKSYYRR
THSDASDDEAFTTSKTKRKGRHRGSEEDPLLSPVETWKGGIDNPAITSDQELDDKKMKKKTHKVKEDKKKKKTKNFNPPTRRNWESNYFG

--------------------------------------------------------------

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Fusion Gene PPI Analysis for ARHGAP5-KIAA0391


check button Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in

ChiPPI page.


check button Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160)
HgeneHgene's interactorsTgeneTgene's interactors


check button - Retained PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenStill interaction with


check button - Lost PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


check button - Retained PPIs, but lost function due to frame-shift fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


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Related Drugs for ARHGAP5-KIAA0391


check button Drugs targeting genes involved in this fusion gene.
(DrugBank Version 5.1.8 2021-05-08)
PartnerGeneUniProtAccDrugBank IDDrug nameDrug activityDrug typeDrug status

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Related Diseases for ARHGAP5-KIAA0391


check button Diseases associated with fusion partners.
(DisGeNet 4.0)
PartnerGeneDisease IDDisease name# pubmedsSource