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 | Fusion Gene Summary |
| Fusion Gene ORF analysis |
| Fusion Genomic Features |
| Fusion Protein Features |
| Fusion Gene Sequence |
| Fusion Gene PPI analysis |
| Related Drugs |
| Related Diseases |
Fusion gene:OPA1-EHHADH (FusionGDB2 ID:61523) |
Fusion Gene Summary for OPA1-EHHADH |
 Fusion gene summary |
| Fusion gene information | Fusion gene name: OPA1-EHHADH | Fusion gene ID: 61523 | Hgene | Tgene | Gene symbol | OPA1 | EHHADH | Gene ID | 9968 | 1962 |
| Gene name | mediator complex subunit 12 | enoyl-CoA hydratase and 3-hydroxyacyl CoA dehydrogenase | |
| Synonyms | ARC240|CAGH45|FGS1|HOPA|Kto|MED12S|OHDOX|OKS|OPA1|TNRC11|TRAP230 | ECHD|FRTS3|L-PBE|LBFP|LBP|PBFE | |
| Cytomap | Xq13.1 | 3q27.2 | |
| Type of gene | protein-coding | protein-coding | |
| Description | mediator of RNA polymerase II transcription subunit 12CAG repeat protein 45Kohtalo homologOPA-containing proteinactivator-recruited cofactor 240 kDa componenthuman opposite pairedmediator of RNA polymerase II transcription, subunit 12 homologputati | peroxisomal bifunctional enzyme3,2-trans-enoyl-CoA isomeraseL-3-hydroxyacyl-CoA dehydrogenaseL-bifunctional protein, peroxisomalPBEenoyl-CoA, hydratase/3-hydroxyacyl CoA dehydrogenaseenoyl-Coenzyme A, hydratase/3-hydroxyacyl Coenzyme A dehydrogenase | |
| Modification date | 20200321 | 20200327 | |
| UniProtAcc | . | Q08426 | |
| Ensembl transtripts involved in fusion gene | ENST00000361150, ENST00000361510, ENST00000361715, ENST00000361828, ENST00000361908, ENST00000392438, ENST00000487986, | ENST00000475987, ENST00000440662, ENST00000231887, ENST00000456310, | |
| Fusion gene scores | * DoF score | 5 X 3 X 4=60 | 6 X 4 X 5=120 |
| # samples | 5 | 7 | |
| ** MAII score | log2(5/60*10)=-0.263034405833794 possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs). DoF>8 and MAII<0 | log2(7/120*10)=-0.777607578663552 possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs). DoF>8 and MAII<0 | |
| Context | PubMed: OPA1 [Title/Abstract] AND EHHADH [Title/Abstract] AND fusion [Title/Abstract] | ||
| Most frequent breakpoint | OPA1(193361894)-EHHADH(184947331), # samples:1 | ||
| Anticipated loss of major functional domain due to fusion event. | |||
| * DoF score (Degree of Frequency) = # partners X # break points X # cancer types ** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10) |
| Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez |
| Partner | Gene | GO ID | GO term | PubMed ID |
| Hgene | OPA1 | GO:0006367 | transcription initiation from RNA polymerase II promoter | 12218053 |
| Hgene | OPA1 | GO:0045893 | positive regulation of transcription, DNA-templated | 10198638 |
| Hgene | OPA1 | GO:0045944 | positive regulation of transcription by RNA polymerase II | 12037571 |
| Tgene | EHHADH | GO:0006475 | internal protein amino acid acetylation | 20167786 |
| Fusion gene breakpoints across OPA1 (5'-gene) * Click on the image to open the UCSC genome browser with custom track showing this image in a new window. |
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| Fusion gene breakpoints across EHHADH (3'-gene) * Click on the image to open the UCSC genome browser with custom track showing this image in a new window. |
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| Fusion gene information from two resources (ChiTars 5.0 and ChimerDB 4.0) * All genome coordinats were lifted-over on hg19. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| Source | Disease | Sample | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| ChimerDB4 | LUSC | TCGA-NC-A5HO-01A | OPA1 | chr3 | 193361894 | - | EHHADH | chr3 | 184947331 | - |
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Fusion Gene ORF analysis for OPA1-EHHADH |
| Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| ORF | Henst | Tenst | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| 5CDS-5UTR | ENST00000361150 | ENST00000475987 | OPA1 | chr3 | 193361894 | - | EHHADH | chr3 | 184947331 | - |
| 5CDS-5UTR | ENST00000361510 | ENST00000475987 | OPA1 | chr3 | 193361894 | - | EHHADH | chr3 | 184947331 | - |
| 5CDS-5UTR | ENST00000361715 | ENST00000475987 | OPA1 | chr3 | 193361894 | - | EHHADH | chr3 | 184947331 | - |
| 5CDS-5UTR | ENST00000361828 | ENST00000475987 | OPA1 | chr3 | 193361894 | - | EHHADH | chr3 | 184947331 | - |
| 5CDS-5UTR | ENST00000361908 | ENST00000475987 | OPA1 | chr3 | 193361894 | - | EHHADH | chr3 | 184947331 | - |
| 5CDS-5UTR | ENST00000392438 | ENST00000475987 | OPA1 | chr3 | 193361894 | - | EHHADH | chr3 | 184947331 | - |
| 5CDS-intron | ENST00000361150 | ENST00000440662 | OPA1 | chr3 | 193361894 | - | EHHADH | chr3 | 184947331 | - |
| 5CDS-intron | ENST00000361510 | ENST00000440662 | OPA1 | chr3 | 193361894 | - | EHHADH | chr3 | 184947331 | - |
| 5CDS-intron | ENST00000361715 | ENST00000440662 | OPA1 | chr3 | 193361894 | - | EHHADH | chr3 | 184947331 | - |
| 5CDS-intron | ENST00000361828 | ENST00000440662 | OPA1 | chr3 | 193361894 | - | EHHADH | chr3 | 184947331 | - |
| 5CDS-intron | ENST00000361908 | ENST00000440662 | OPA1 | chr3 | 193361894 | - | EHHADH | chr3 | 184947331 | - |
| 5CDS-intron | ENST00000392438 | ENST00000440662 | OPA1 | chr3 | 193361894 | - | EHHADH | chr3 | 184947331 | - |
| In-frame | ENST00000361150 | ENST00000231887 | OPA1 | chr3 | 193361894 | - | EHHADH | chr3 | 184947331 | - |
| In-frame | ENST00000361150 | ENST00000456310 | OPA1 | chr3 | 193361894 | - | EHHADH | chr3 | 184947331 | - |
| In-frame | ENST00000361510 | ENST00000231887 | OPA1 | chr3 | 193361894 | - | EHHADH | chr3 | 184947331 | - |
| In-frame | ENST00000361510 | ENST00000456310 | OPA1 | chr3 | 193361894 | - | EHHADH | chr3 | 184947331 | - |
| In-frame | ENST00000361715 | ENST00000231887 | OPA1 | chr3 | 193361894 | - | EHHADH | chr3 | 184947331 | - |
| In-frame | ENST00000361715 | ENST00000456310 | OPA1 | chr3 | 193361894 | - | EHHADH | chr3 | 184947331 | - |
| In-frame | ENST00000361828 | ENST00000231887 | OPA1 | chr3 | 193361894 | - | EHHADH | chr3 | 184947331 | - |
| In-frame | ENST00000361828 | ENST00000456310 | OPA1 | chr3 | 193361894 | - | EHHADH | chr3 | 184947331 | - |
| In-frame | ENST00000361908 | ENST00000231887 | OPA1 | chr3 | 193361894 | - | EHHADH | chr3 | 184947331 | - |
| In-frame | ENST00000361908 | ENST00000456310 | OPA1 | chr3 | 193361894 | - | EHHADH | chr3 | 184947331 | - |
| In-frame | ENST00000392438 | ENST00000231887 | OPA1 | chr3 | 193361894 | - | EHHADH | chr3 | 184947331 | - |
| In-frame | ENST00000392438 | ENST00000456310 | OPA1 | chr3 | 193361894 | - | EHHADH | chr3 | 184947331 | - |
| intron-3CDS | ENST00000487986 | ENST00000231887 | OPA1 | chr3 | 193361894 | - | EHHADH | chr3 | 184947331 | - |
| intron-3CDS | ENST00000487986 | ENST00000456310 | OPA1 | chr3 | 193361894 | - | EHHADH | chr3 | 184947331 | - |
| intron-5UTR | ENST00000487986 | ENST00000475987 | OPA1 | chr3 | 193361894 | - | EHHADH | chr3 | 184947331 | - |
| intron-intron | ENST00000487986 | ENST00000440662 | OPA1 | chr3 | 193361894 | - | EHHADH | chr3 | 184947331 | - |
| ORFfinder result based on the fusion transcript sequence of in-frame fusion genes. |
| Henst | Tenst | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand | Seq length (transcript) | BP loci (transcript) | Predicted start (transcript) | Predicted stop (transcript) | Seq length (amino acids) |
| ENST00000361828 | OPA1 | chr3 | 193361894 | - | ENST00000231887 | EHHADH | chr3 | 184947331 | - | 5154 | 1731 | 45 | 3551 | 1168 |
| ENST00000361828 | OPA1 | chr3 | 193361894 | - | ENST00000456310 | EHHADH | chr3 | 184947331 | - | 3808 | 1731 | 45 | 3551 | 1168 |
| ENST00000361510 | OPA1 | chr3 | 193361894 | - | ENST00000231887 | EHHADH | chr3 | 184947331 | - | 5265 | 1842 | 45 | 3662 | 1205 |
| ENST00000361510 | OPA1 | chr3 | 193361894 | - | ENST00000456310 | EHHADH | chr3 | 184947331 | - | 3919 | 1842 | 45 | 3662 | 1205 |
| ENST00000361150 | OPA1 | chr3 | 193361894 | - | ENST00000231887 | EHHADH | chr3 | 184947331 | - | 5103 | 1680 | 45 | 3500 | 1151 |
| ENST00000361150 | OPA1 | chr3 | 193361894 | - | ENST00000456310 | EHHADH | chr3 | 184947331 | - | 3757 | 1680 | 45 | 3500 | 1151 |
| ENST00000361715 | OPA1 | chr3 | 193361894 | - | ENST00000231887 | EHHADH | chr3 | 184947331 | - | 5157 | 1734 | 45 | 3554 | 1169 |
| ENST00000361715 | OPA1 | chr3 | 193361894 | - | ENST00000456310 | EHHADH | chr3 | 184947331 | - | 3811 | 1734 | 45 | 3554 | 1169 |
| ENST00000361908 | OPA1 | chr3 | 193361894 | - | ENST00000231887 | EHHADH | chr3 | 184947331 | - | 5211 | 1788 | 45 | 3608 | 1187 |
| ENST00000361908 | OPA1 | chr3 | 193361894 | - | ENST00000456310 | EHHADH | chr3 | 184947331 | - | 3865 | 1788 | 45 | 3608 | 1187 |
| ENST00000392438 | OPA1 | chr3 | 193361894 | - | ENST00000231887 | EHHADH | chr3 | 184947331 | - | 5100 | 1677 | 45 | 3497 | 1150 |
| ENST00000392438 | OPA1 | chr3 | 193361894 | - | ENST00000456310 | EHHADH | chr3 | 184947331 | - | 3754 | 1677 | 45 | 3497 | 1150 |
| DeepORF prediction of the coding potential based on the fusion transcript sequence of in-frame fusion genes. DeepORF is a coding potential classifier based on convolutional neural network by comparing the real Ribo-seq data. If the no-coding score < 0.5 and coding score > 0.5, then the in-frame fusion transcript is predicted as being likely translated. |
| Henst | Tenst | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand | No-coding score | Coding score |
| ENST00000361828 | ENST00000231887 | OPA1 | chr3 | 193361894 | - | EHHADH | chr3 | 184947331 | - | 0.000284158 | 0.99971586 |
| ENST00000361828 | ENST00000456310 | OPA1 | chr3 | 193361894 | - | EHHADH | chr3 | 184947331 | - | 0.000998994 | 0.99900097 |
| ENST00000361510 | ENST00000231887 | OPA1 | chr3 | 193361894 | - | EHHADH | chr3 | 184947331 | - | 0.000161139 | 0.9998388 |
| ENST00000361510 | ENST00000456310 | OPA1 | chr3 | 193361894 | - | EHHADH | chr3 | 184947331 | - | 0.000647713 | 0.9993523 |
| ENST00000361150 | ENST00000231887 | OPA1 | chr3 | 193361894 | - | EHHADH | chr3 | 184947331 | - | 8.70E-05 | 0.999913 |
| ENST00000361150 | ENST00000456310 | OPA1 | chr3 | 193361894 | - | EHHADH | chr3 | 184947331 | - | 0.000431669 | 0.9995683 |
| ENST00000361715 | ENST00000231887 | OPA1 | chr3 | 193361894 | - | EHHADH | chr3 | 184947331 | - | 0.000135073 | 0.99986494 |
| ENST00000361715 | ENST00000456310 | OPA1 | chr3 | 193361894 | - | EHHADH | chr3 | 184947331 | - | 0.00058875 | 0.9994112 |
| ENST00000361908 | ENST00000231887 | OPA1 | chr3 | 193361894 | - | EHHADH | chr3 | 184947331 | - | 9.19E-05 | 0.9999081 |
| ENST00000361908 | ENST00000456310 | OPA1 | chr3 | 193361894 | - | EHHADH | chr3 | 184947331 | - | 0.00040819 | 0.99959177 |
| ENST00000392438 | ENST00000231887 | OPA1 | chr3 | 193361894 | - | EHHADH | chr3 | 184947331 | - | 7.83E-05 | 0.9999217 |
| ENST00000392438 | ENST00000456310 | OPA1 | chr3 | 193361894 | - | EHHADH | chr3 | 184947331 | - | 0.00035108 | 0.9996489 |
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Fusion Genomic Features for OPA1-EHHADH |
| FusionAI prediction of the potential fusion gene breakpoint based on the pre-mature RNA sequence context (+/- 5kb of individual partner genes, total 20kb length sequence). FusionAI is a fusion gene breakpoint classifier based on convolutional neural network by comparing the fusion positive and negative sequence context of ~ 20K fusion gene data. From here, we can have the relative potentency of the 20K genomic sequence how individual sequnce will be likely used as the gene fusion breakpoints. |
| Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand | 1-p | p (fusion gene breakpoint) |
| Distribution of 44 human genomic features loci across 20kb length fusion breakpoint regions. We integrated a total of 44 different types of human genomic feature loci information across five big categories including virus integration sites, repeats, structural variants, chromatin states, and gene expression regulation. More details are in help page. |
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| Distribution of 44 human genomic features loci across 20kb length fusion breakpoint regions that are ovelapped with the top 1% feature importance score regions. More details are in help page. |
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Fusion Protein Features for OPA1-EHHADH |
| Four levels of functional features of fusion genes Go to FGviewer search page for the most frequent breakpoint (https://ccsmweb.uth.edu/FGviewer/chr3:193361894/chr3:184947331) - FGviewer provides the online visualization of the retention search of the protein functional features across DNA, RNA, protein, and pathological levels. - How to search 1. Put your fusion gene symbol. 2. Press the tab key until there will be shown the breakpoint information filled. 4. Go down and press 'Search' tab twice. 4. Go down to have the hyperlink of the search result. 5. Click the hyperlink. 6. See the FGviewer result for your fusion gene. |
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| Main function of each fusion partner protein. (from UniProt) |
| Hgene | Tgene |
| . | EHHADH |
| FUNCTION: Transcriptional activator which is required for calcium-dependent dendritic growth and branching in cortical neurons. Recruits CREB-binding protein (CREBBP) to nuclear bodies. Component of the CREST-BRG1 complex, a multiprotein complex that regulates promoter activation by orchestrating a calcium-dependent release of a repressor complex and a recruitment of an activator complex. In resting neurons, transcription of the c-FOS promoter is inhibited by BRG1-dependent recruitment of a phospho-RB1-HDAC1 repressor complex. Upon calcium influx, RB1 is dephosphorylated by calcineurin, which leads to release of the repressor complex. At the same time, there is increased recruitment of CREBBP to the promoter by a CREST-dependent mechanism, which leads to transcriptional activation. The CREST-BRG1 complex also binds to the NR2B promoter, and activity-dependent induction of NR2B expression involves a release of HDAC1 and recruitment of CREBBP (By similarity). {ECO:0000250}. | FUNCTION: Peroxisomal trifunctional enzyme possessing 2-enoyl-CoA hydratase, 3-hydroxyacyl-CoA dehydrogenase, and delta 3, delta 2-enoyl-CoA isomerase activities. Catalyzes two of the four reactions of the long straight chain fatty acids peroxisomal beta-oxidation pathway. Optimal isomerase for 2,5 double bonds into 3,5 form isomerization in a range of enoyl-CoA species (Probable). Also able to isomerize both 3-cis and 3-trans double bonds into the 2-trans form in a range of enoyl-CoA species (By similarity). With HSD17B4, catalyzes the hydration of trans-2-enoyl-CoA and the dehydrogenation of 3-hydroxyacyl-CoA, but with opposite chiral specificity (PubMed:15060085). Regulates the amount of medium-chain dicarboxylic fatty acids which are essential regulators of all fatty acid oxidation pathways (By similarity). Also involved in the degradation of long-chain dicarboxylic acids through peroxisomal beta-oxidation (PubMed:15060085). {ECO:0000250|UniProtKB:P07896, ECO:0000250|UniProtKB:Q9DBM2, ECO:0000269|PubMed:15060085, ECO:0000305|PubMed:15060085}. |
| Retention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at * Minus value of BPloci means that the break pointn is located before the CDS. |
| - In-frame and retained protein feature among the 13 regional features. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Protein feature | Protein feature note |
| Hgene | OPA1 | chr3:193361894 | chr3:184947331 | ENST00000361908 | - | 15 | 30 | 210_254 | 518 | 1978.0 | Coiled coil | Ontology_term=ECO:0000255 |
| Hgene | OPA1 | chr3:193361894 | chr3:184947331 | ENST00000392438 | - | 14 | 29 | 210_254 | 481 | 1945.0 | Coiled coil | Ontology_term=ECO:0000255 |
| Hgene | OPA1 | chr3:193361894 | chr3:184947331 | ENST00000361908 | - | 15 | 30 | 398_402 | 518 | 1978.0 | Nucleotide binding | GTP |
| Hgene | OPA1 | chr3:193361894 | chr3:184947331 | ENST00000392438 | - | 14 | 29 | 398_402 | 481 | 1945.0 | Nucleotide binding | GTP |
| Hgene | OPA1 | chr3:193361894 | chr3:184947331 | ENST00000361908 | - | 15 | 30 | 295_302 | 518 | 1978.0 | Region | G1 motif |
| Hgene | OPA1 | chr3:193361894 | chr3:184947331 | ENST00000361908 | - | 15 | 30 | 321_324 | 518 | 1978.0 | Region | G2 motif |
| Hgene | OPA1 | chr3:193361894 | chr3:184947331 | ENST00000361908 | - | 15 | 30 | 398_401 | 518 | 1978.0 | Region | G3 motif |
| Hgene | OPA1 | chr3:193361894 | chr3:184947331 | ENST00000361908 | - | 15 | 30 | 467_470 | 518 | 1978.0 | Region | G4 motif |
| Hgene | OPA1 | chr3:193361894 | chr3:184947331 | ENST00000361908 | - | 15 | 30 | 501_504 | 518 | 1978.0 | Region | G5 motif |
| Hgene | OPA1 | chr3:193361894 | chr3:184947331 | ENST00000392438 | - | 14 | 29 | 295_302 | 481 | 1945.0 | Region | G1 motif |
| Hgene | OPA1 | chr3:193361894 | chr3:184947331 | ENST00000392438 | - | 14 | 29 | 321_324 | 481 | 1945.0 | Region | G2 motif |
| Hgene | OPA1 | chr3:193361894 | chr3:184947331 | ENST00000392438 | - | 14 | 29 | 398_401 | 481 | 1945.0 | Region | G3 motif |
| Hgene | OPA1 | chr3:193361894 | chr3:184947331 | ENST00000392438 | - | 14 | 29 | 467_470 | 481 | 1945.0 | Region | G4 motif |
| Hgene | OPA1 | chr3:193361894 | chr3:184947331 | ENST00000361908 | - | 15 | 30 | 88_96 | 518 | 1978.0 | Topological domain | Mitochondrial matrix |
| Hgene | OPA1 | chr3:193361894 | chr3:184947331 | ENST00000392438 | - | 14 | 29 | 88_96 | 481 | 1945.0 | Topological domain | Mitochondrial matrix |
| Hgene | OPA1 | chr3:193361894 | chr3:184947331 | ENST00000361908 | - | 15 | 30 | 97_113 | 518 | 1978.0 | Transmembrane | Helical |
| Hgene | OPA1 | chr3:193361894 | chr3:184947331 | ENST00000392438 | - | 14 | 29 | 97_113 | 481 | 1945.0 | Transmembrane | Helical |
| Tgene | EHHADH | chr3:193361894 | chr3:184947331 | ENST00000231887 | 2 | 7 | 721_723 | 117 | 724.0 | Motif | Note=Microbody targeting signal | |
| Tgene | EHHADH | chr3:193361894 | chr3:184947331 | ENST00000456310 | 2 | 7 | 721_723 | 21 | 628.0 | Motif | Note=Microbody targeting signal | |
| Tgene | EHHADH | chr3:193361894 | chr3:184947331 | ENST00000231887 | 2 | 7 | 283_572 | 117 | 724.0 | Region | Note=3-hydroxyacyl-CoA dehydrogenase | |
| Tgene | EHHADH | chr3:193361894 | chr3:184947331 | ENST00000456310 | 2 | 7 | 283_572 | 21 | 628.0 | Region | Note=3-hydroxyacyl-CoA dehydrogenase |
| - In-frame and not-retained protein feature among the 13 regional features. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Protein feature | Protein feature note |
| Hgene | OPA1 | chr3:193361894 | chr3:184947331 | ENST00000361908 | - | 15 | 30 | 895_960 | 518 | 1978.0 | Coiled coil | Ontology_term=ECO:0000255 |
| Hgene | OPA1 | chr3:193361894 | chr3:184947331 | ENST00000392438 | - | 14 | 29 | 895_960 | 481 | 1945.0 | Coiled coil | Ontology_term=ECO:0000255 |
| Hgene | OPA1 | chr3:193361894 | chr3:184947331 | ENST00000361908 | - | 15 | 30 | 285_561 | 518 | 1978.0 | Domain | Dynamin-type G |
| Hgene | OPA1 | chr3:193361894 | chr3:184947331 | ENST00000392438 | - | 14 | 29 | 285_561 | 481 | 1945.0 | Domain | Dynamin-type G |
| Hgene | OPA1 | chr3:193361894 | chr3:184947331 | ENST00000392438 | - | 14 | 29 | 501_504 | 481 | 1945.0 | Region | G5 motif |
| Hgene | OPA1 | chr3:193361894 | chr3:184947331 | ENST00000361908 | - | 15 | 30 | 114_960 | 518 | 1978.0 | Topological domain | Mitochondrial intermembrane |
| Hgene | OPA1 | chr3:193361894 | chr3:184947331 | ENST00000392438 | - | 14 | 29 | 114_960 | 481 | 1945.0 | Topological domain | Mitochondrial intermembrane |
| Tgene | EHHADH | chr3:193361894 | chr3:184947331 | ENST00000231887 | 2 | 7 | 1_282 | 117 | 724.0 | Region | Note=Enoyl-CoA hydratase / isomerase | |
| Tgene | EHHADH | chr3:193361894 | chr3:184947331 | ENST00000456310 | 2 | 7 | 1_282 | 21 | 628.0 | Region | Note=Enoyl-CoA hydratase / isomerase |
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Fusion Gene Sequence for OPA1-EHHADH |
| For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. To have fusion amino acid sequence, we ran ORFfinder and chose the longest ORF among the all predicted ones. |
| >61523_61523_1_OPA1-EHHADH_OPA1_chr3_193361894_ENST00000361150_EHHADH_chr3_184947331_ENST00000231887_length(transcript)=5103nt_BP=1680nt GTGCTGCCCGCCTAGAAAGGGTGAAGTGGTTGTTTCCGTGACGGACTGAGTACGGGTGCCTGTCAGGCTCTTGCGGAAGTCCATGCGCCA TTGGGAGGGCCTCGGCCGCGGCTCTGTGCCCTTGCTGCTGAGGGCCACTTCCTGGGTCATTCCTGGACCGGGAGCCGGGCTGGGGCTCAC ACGGGGGCTCCCGCGTGGCCGTCTCGGCGCCTGCGTGACCTCCCCGCCGGCGGGATGTGGCGACTACGTCGGGCCGCTGTGGCCTGTGAG GTCTGCCAGTCTTTAGTGAAACACAGCTCTGGAATAAAAGGAAGTTTACCACTACAAAAACTACATCTGGTTTCACGAAGCATTTATCAT TCACATCATCCTACCTTAAAGCTTCAACGACCCCAATTAAGGACATCCTTTCAGCAGTTCTCTTCTCTGACAAACCTTCCTTTACGTAAA CTGAAATTCTCTCCAATTAAATATGGCTACCAGCCTCGCAGGAATTTTTGGCCAGCAAGATTAGCTACGAGACTCTTAAAACTTCGCTAT CTCATACTAGGATCGGCTGTTGGGGGTGGCTACACAGCCAAAAAGACTTTTGATCAGTGGAAAGATATGATACCGGACCTTAGTGAATAT AAATGGATTGTGCCTGACATTGTGTGGGAAATTGATGAGTATATCGATTTTGGTTCTCCGGAAGAAACGGCGTTTAGAGCAACAGATCGT GGATCTGAAAGTGACAAGCATTTTAGAAAGGGTCTGCTTGGTGAGCTCATTCTCTTACAACAACAAATTCAAGAGCATGAAGAGGAAGCG CGCAGAGCCGCTGGCCAATATAGCACGAGCTATGCCCAACAGAAGCGCAAGGTGTCAGACAAAGAGAAAATTGACCAACTTCAGGAAGAA CTTCTGCACACTCAGTTGAAGTATCAGAGAATCTTGGAACGATTAGAAAAGGAGAACAAAGAATTGAGAAAATTAGTATTGCAGAAAGAT GACAAAGGCATTCATCATAGAAAGCTTAAGAAATCTTTGATTGACATGTATTCTGAAGTTCTTGATGTTCTCTCTGATTATGATGCCAGT TATAATACGCAAGATCATCTGCCACGGGTTGTTGTGGTTGGAGATCAGAGTGCTGGAAAGACTAGTGTGTTGGAAATGATTGCCCAAGCT CGAATATTCCCAAGAGGATCTGGGGAGATGATGACACGTTCTCCAGTTAAGGTGACTCTGAGTGAAGGTCCTCACCATGTGGCCCTATTT AAAGATAGTTCTCGGGAGTTTGATCTTACCAAAGAAGAAGATCTTGCAGCATTAAGACATGAAATAGAACTTCGAATGAGGAAAAATGTG AAAGAAGGCTGTACCGTTAGCCCTGAGACCATATCCTTAAATGTAAAAGGCCCTGGACTACAGAGGATGGTGCTTGTTGACTTACCAGGT GTGATTAATACTGTGACATCAGGCATGGCTCCTGACACAAAGGAAACTATTTTCAGTATCAGCAAAGCTTACATGCAGAATCCTAATGCC ATCATACTGTGTATTCAAGATGGATCTGTGGATGCTGAACGCAGTATTGTTACAGACTTGGTCAGTCAAATGGACCCTCATGGAAGGAGA ACCATATTCGTTTTGACCAAAGTAGACCTGGCAGAGAAAAATGTAGCCAGTCCAAGCAGGGCTCAAGTTGGCTTACCAGAAGTTACACTG GGACTTCTCCCTGGTGCAAGAGGAACCCAGCTTCTCCCCAGACTCACTGGAGTTCCTGCTGCACTTGACTTAATTACCTCAGGAAGACGT ATTTTAGCAGATGAAGCACTCAAGCTGGGCATTCTAGATAAAGTTGTAAACTCAGACCCGGTTGAAGAAGCAATCAGATTTGCTCAGAGA GTTTCAGATCAACCTCTAGAATCCCGTAGACTCTGCAACAAGCCAATTCAGAGCTTGCCCAACATGGACAGCATTTTTAGTGAGGCCCTC TTGAAGATGCGGAGGCAGCACCCTGGGTGTCTTGCACAGGAGGCTTGTGTCCGTGCAGTCCAGGCTGCTGTGCAGTATCCCTATGAAGTG GGCATCAAGAAGGAGGAGGAGCTGTTTCTATATCTTTTGCAATCAGGGCAGGCTAGAGCCCTGCAATATGCTTTCTTCGCTGAAAGGAAA GCAAATAAGTGGTCAACTCCCTCCGGAGCATCGTGGAAAACAGCATCAGCGCGGCCTGTCTCCTCAGTTGGTGTTGTTGGCTTGGGAACA ATGGGCCGAGGCATTGTCATTTCTTTTGCAAGGGCCAGGATTCCTGTGATTGCTGTAGACTCGGACAAAAACCAGCTAGCAACTGCAAAC AAGATGATAACCTCTGTCTTGGAAAAAGAAGCCTCCAAAATGCAACAGAGCGGCCACCCTTGGTCAGGACCAAAACCCAGGTTAACTTCA TCTGTGAAGGAGCTTGGTGGTGTAGATTTAGTCATTGAAGCAGTATTTGAGGAAATGAGCCTGAAGAAGCAGGTCTTTGCTGAACTCTCA GCTGTGTGCAAACCAGAAGCATTTTTGTGCACTAATACTTCAGCCCTGGATGTTGATGAGATTGCTTCTTCCACTGATCGTCCTCACTTG GTCATTGGCACCCACTTCTTTTCGCCAGCTCATGTCATGAAGTTGTTAGAGGTTATTCCCAGCCAATACTCTTCCCCCACTACCATTGCC ACTGTTATGAACTTATCAAAAAAGATTAAAAAGATTGGAGTCGTTGTAGGCAACTGTTTTGGATTTGTGGGGAATCGAATGTTGAATCCT TACTACAATCAGGCATATTTCTTGTTAGAAGAAGGCAGCAAACCAGAGGAGGTAGATCAGGTGCTGGAAGAGTTTGGTTTTAAAATGGGA CCTTTTAGAGTGTCTGATCTTGCTGGGTTGGATGTGGGCTGGAAATCTAGAAAGGGGCAAGGTCTTACTGGACCTACATTGCTTCCAGGA ACTCCTGCCCGAAAAAGGGGTAATAGGAGGTACTGCCCAATTCCTGATGTGCTCTGTGAATTAGGACGATTTGGCCAGAAGACAGGTAAG GGTTGGTATCAATATGACAAGCCATTGGGTAGGATTCACAAACCTGATCCCTGGCTTTCCAAATTCCTATCACGGTATAGAAAAACCCAT CACATTGAACCACGTACCATTAGCCAGGATGAGATCCTTGAACGCTGCTTATATTCACTTATCAATGAAGCATTCCGTATCTTGGGAGAA GGGATAGCTGCTAGCCCAGAGCACATTGATGTTGTCTATTTACATGGATATGGATGGCCAAGGCACAAGGGCGGGCCCATGTTCTATGCT TCCACAGTTGGGTTGCCCACAGTTCTAGAGAAATTGCAGAAATATTACAGGCAGAACCCTGATATTCCCCAACTGGAGCCAAGTGACTAT CTAAAAAAACTGGCTTCTCAGGGAAACCCTCCCCTGAAAGAATGGCAAAGCTTGGCAGGCTCCCCTAGCAGTAAATTGTGATTCAGTCTT CCAGATTATGCCTCACATGCTAGCATCAGGTAATGCTGACTGAATTTCAGTGAAATTAAATCAAAAATCCAAAGTAAGATTGTTCTGAAA TACAAAGCAAAATAAATAATCATTAGAATCTTCTGTGTAACGACTCTAATGGTCAAATCTTTAGGAATGTGCTTCCTATGCCTCTGAATC TGTCCTTATCAGATAAATTCAATGCATGAACTTGTGTGAATATAATACCATAATAGCTAATGAAAGAGGCTCAGGCATAAGTTGAGATTC TCAAATGCTTTTATCATTGGATAAATGTGTCATCAATTAATAAATGATAAATGCAGCTAAGTCATACATTCATTTTGACTCCTTTCAATG TCACACACATAGTATTGATCAGAAATCTTATGAATCATACATACACTCAACAAACATTAAAGTTGTAGGAAAAAGACAGTTGGAAATTGG TAAGGGAACTGAGTACTTCAAACCAGCACAGGGAACTTAGGTTAGTGTGGCAAGCCTTTCCTCTTCTGGTCTTTCCTCTTCTGTTTATGG AGAAATAATAGAAAGTAGTAAGTCGTTAACTTAGTGTAAGAAGGGTCTTAGAGAACATCTAACCTTCTAGGATTTCCCAATTCTGTGATA GAGTAATGACACCAGTTTTCCTGTCATGACAAGCCTCTGTGATGTTACATATGGAAATGGTTGAATCTTGAAAAATCTAAAATTGTTGCA AAACATATTTTGTATGATTTTGTTGTAAGAGTTCTTCTCTTTTTACTTTTTGCCTTGTGTAGTTAAAAATTAAGGGGCTGGTCAATACAA AAACTTGTACACAAATATTTATAGCAGAATTATTCATAATGGCCAAAAGCTGAATACAACCCAAATGTCTATGAACTAATGAATAGATAA ACCAAATCTGGTATATCCATACAATGGACTATATTATTCAGCCATAAAAAGAAATAAAGGGCCAGGCACAGTGGCTCACACCTGTAATCC CAGCACTTTGGGAGGCTGAGGCAGGAGGATTGTTTGAGGCCAGAAATTTGAGACCAGCCTGGGCAACATAGCAAAACCCTGTCTCTACAA AAAATACTTTCCGTACATTAGTGGTTGCCTAAGGCTAGAATTGGGGGTGATGAATGGGGAGTACAGGATTCATCTAATGGGTACAGGATT TCTTTATGGTTCATGAAAATGGTCTAAACTTATTGTGGTAATGGTCACATAACAATATATTAAAAACCATTGAGTTGTATATTTTAAGTG GGTGAATTATATGGTATGTGAATTATATCTCAATAAAGTTGTTAGTAAATAAATGGGGCTGAAGATGTTATCCTTCATTGTGGTGTAAAT GAACTTTCACAATATTTTCACCTGTGAACCCAAATAAAATGATTAAAGTTCTGATGGAAAAATCTTGAATGGAGTATAAGTTTTCCGTTG TTAAAAAGCAAACAAAAAACCAACAAAAAATCCAAGTGTGCCTTGAATTGTACAGAGCACAATTATTATGTTTGAAATGTGTACTACTTA >61523_61523_1_OPA1-EHHADH_OPA1_chr3_193361894_ENST00000361150_EHHADH_chr3_184947331_ENST00000231887_length(amino acids)=1151AA_BP=545 MSTGACQALAEVHAPLGGPRPRLCALAAEGHFLGHSWTGSRAGAHTGAPAWPSRRLRDLPAGGMWRLRRAAVACEVCQSLVKHSSGIKGS LPLQKLHLVSRSIYHSHHPTLKLQRPQLRTSFQQFSSLTNLPLRKLKFSPIKYGYQPRRNFWPARLATRLLKLRYLILGSAVGGGYTAKK TFDQWKDMIPDLSEYKWIVPDIVWEIDEYIDFGSPEETAFRATDRGSESDKHFRKGLLGELILLQQQIQEHEEEARRAAGQYSTSYAQQK RKVSDKEKIDQLQEELLHTQLKYQRILERLEKENKELRKLVLQKDDKGIHHRKLKKSLIDMYSEVLDVLSDYDASYNTQDHLPRVVVVGD QSAGKTSVLEMIAQARIFPRGSGEMMTRSPVKVTLSEGPHHVALFKDSSREFDLTKEEDLAALRHEIELRMRKNVKEGCTVSPETISLNV KGPGLQRMVLVDLPGVINTVTSGMAPDTKETIFSISKAYMQNPNAIILCIQDGSVDAERSIVTDLVSQMDPHGRRTIFVLTKVDLAEKNV ASPSRAQVGLPEVTLGLLPGARGTQLLPRLTGVPAALDLITSGRRILADEALKLGILDKVVNSDPVEEAIRFAQRVSDQPLESRRLCNKP IQSLPNMDSIFSEALLKMRRQHPGCLAQEACVRAVQAAVQYPYEVGIKKEEELFLYLLQSGQARALQYAFFAERKANKWSTPSGASWKTA SARPVSSVGVVGLGTMGRGIVISFARARIPVIAVDSDKNQLATANKMITSVLEKEASKMQQSGHPWSGPKPRLTSSVKELGGVDLVIEAV FEEMSLKKQVFAELSAVCKPEAFLCTNTSALDVDEIASSTDRPHLVIGTHFFSPAHVMKLLEVIPSQYSSPTTIATVMNLSKKIKKIGVV VGNCFGFVGNRMLNPYYNQAYFLLEEGSKPEEVDQVLEEFGFKMGPFRVSDLAGLDVGWKSRKGQGLTGPTLLPGTPARKRGNRRYCPIP DVLCELGRFGQKTGKGWYQYDKPLGRIHKPDPWLSKFLSRYRKTHHIEPRTISQDEILERCLYSLINEAFRILGEGIAASPEHIDVVYLH -------------------------------------------------------------- >61523_61523_2_OPA1-EHHADH_OPA1_chr3_193361894_ENST00000361150_EHHADH_chr3_184947331_ENST00000456310_length(transcript)=3757nt_BP=1680nt GTGCTGCCCGCCTAGAAAGGGTGAAGTGGTTGTTTCCGTGACGGACTGAGTACGGGTGCCTGTCAGGCTCTTGCGGAAGTCCATGCGCCA TTGGGAGGGCCTCGGCCGCGGCTCTGTGCCCTTGCTGCTGAGGGCCACTTCCTGGGTCATTCCTGGACCGGGAGCCGGGCTGGGGCTCAC ACGGGGGCTCCCGCGTGGCCGTCTCGGCGCCTGCGTGACCTCCCCGCCGGCGGGATGTGGCGACTACGTCGGGCCGCTGTGGCCTGTGAG GTCTGCCAGTCTTTAGTGAAACACAGCTCTGGAATAAAAGGAAGTTTACCACTACAAAAACTACATCTGGTTTCACGAAGCATTTATCAT TCACATCATCCTACCTTAAAGCTTCAACGACCCCAATTAAGGACATCCTTTCAGCAGTTCTCTTCTCTGACAAACCTTCCTTTACGTAAA CTGAAATTCTCTCCAATTAAATATGGCTACCAGCCTCGCAGGAATTTTTGGCCAGCAAGATTAGCTACGAGACTCTTAAAACTTCGCTAT CTCATACTAGGATCGGCTGTTGGGGGTGGCTACACAGCCAAAAAGACTTTTGATCAGTGGAAAGATATGATACCGGACCTTAGTGAATAT AAATGGATTGTGCCTGACATTGTGTGGGAAATTGATGAGTATATCGATTTTGGTTCTCCGGAAGAAACGGCGTTTAGAGCAACAGATCGT GGATCTGAAAGTGACAAGCATTTTAGAAAGGGTCTGCTTGGTGAGCTCATTCTCTTACAACAACAAATTCAAGAGCATGAAGAGGAAGCG CGCAGAGCCGCTGGCCAATATAGCACGAGCTATGCCCAACAGAAGCGCAAGGTGTCAGACAAAGAGAAAATTGACCAACTTCAGGAAGAA CTTCTGCACACTCAGTTGAAGTATCAGAGAATCTTGGAACGATTAGAAAAGGAGAACAAAGAATTGAGAAAATTAGTATTGCAGAAAGAT GACAAAGGCATTCATCATAGAAAGCTTAAGAAATCTTTGATTGACATGTATTCTGAAGTTCTTGATGTTCTCTCTGATTATGATGCCAGT TATAATACGCAAGATCATCTGCCACGGGTTGTTGTGGTTGGAGATCAGAGTGCTGGAAAGACTAGTGTGTTGGAAATGATTGCCCAAGCT CGAATATTCCCAAGAGGATCTGGGGAGATGATGACACGTTCTCCAGTTAAGGTGACTCTGAGTGAAGGTCCTCACCATGTGGCCCTATTT AAAGATAGTTCTCGGGAGTTTGATCTTACCAAAGAAGAAGATCTTGCAGCATTAAGACATGAAATAGAACTTCGAATGAGGAAAAATGTG AAAGAAGGCTGTACCGTTAGCCCTGAGACCATATCCTTAAATGTAAAAGGCCCTGGACTACAGAGGATGGTGCTTGTTGACTTACCAGGT GTGATTAATACTGTGACATCAGGCATGGCTCCTGACACAAAGGAAACTATTTTCAGTATCAGCAAAGCTTACATGCAGAATCCTAATGCC ATCATACTGTGTATTCAAGATGGATCTGTGGATGCTGAACGCAGTATTGTTACAGACTTGGTCAGTCAAATGGACCCTCATGGAAGGAGA ACCATATTCGTTTTGACCAAAGTAGACCTGGCAGAGAAAAATGTAGCCAGTCCAAGCAGGGCTCAAGTTGGCTTACCAGAAGTTACACTG GGACTTCTCCCTGGTGCAAGAGGAACCCAGCTTCTCCCCAGACTCACTGGAGTTCCTGCTGCACTTGACTTAATTACCTCAGGAAGACGT ATTTTAGCAGATGAAGCACTCAAGCTGGGCATTCTAGATAAAGTTGTAAACTCAGACCCGGTTGAAGAAGCAATCAGATTTGCTCAGAGA GTTTCAGATCAACCTCTAGAATCCCGTAGACTCTGCAACAAGCCAATTCAGAGCTTGCCCAACATGGACAGCATTTTTAGTGAGGCCCTC TTGAAGATGCGGAGGCAGCACCCTGGGTGTCTTGCACAGGAGGCTTGTGTCCGTGCAGTCCAGGCTGCTGTGCAGTATCCCTATGAAGTG GGCATCAAGAAGGAGGAGGAGCTGTTTCTATATCTTTTGCAATCAGGGCAGGCTAGAGCCCTGCAATATGCTTTCTTCGCTGAAAGGAAA GCAAATAAGTGGTCAACTCCCTCCGGAGCATCGTGGAAAACAGCATCAGCGCGGCCTGTCTCCTCAGTTGGTGTTGTTGGCTTGGGAACA ATGGGCCGAGGCATTGTCATTTCTTTTGCAAGGGCCAGGATTCCTGTGATTGCTGTAGACTCGGACAAAAACCAGCTAGCAACTGCAAAC AAGATGATAACCTCTGTCTTGGAAAAAGAAGCCTCCAAAATGCAACAGAGCGGCCACCCTTGGTCAGGACCAAAACCCAGGTTAACTTCA TCTGTGAAGGAGCTTGGTGGTGTAGATTTAGTCATTGAAGCAGTATTTGAGGAAATGAGCCTGAAGAAGCAGGTCTTTGCTGAACTCTCA GCTGTGTGCAAACCAGAAGCATTTTTGTGCACTAATACTTCAGCCCTGGATGTTGATGAGATTGCTTCTTCCACTGATCGTCCTCACTTG GTCATTGGCACCCACTTCTTTTCGCCAGCTCATGTCATGAAGTTGTTAGAGGTTATTCCCAGCCAATACTCTTCCCCCACTACCATTGCC ACTGTTATGAACTTATCAAAAAAGATTAAAAAGATTGGAGTCGTTGTAGGCAACTGTTTTGGATTTGTGGGGAATCGAATGTTGAATCCT TACTACAATCAGGCATATTTCTTGTTAGAAGAAGGCAGCAAACCAGAGGAGGTAGATCAGGTGCTGGAAGAGTTTGGTTTTAAAATGGGA CCTTTTAGAGTGTCTGATCTTGCTGGGTTGGATGTGGGCTGGAAATCTAGAAAGGGGCAAGGTCTTACTGGACCTACATTGCTTCCAGGA ACTCCTGCCCGAAAAAGGGGTAATAGGAGGTACTGCCCAATTCCTGATGTGCTCTGTGAATTAGGACGATTTGGCCAGAAGACAGGTAAG GGTTGGTATCAATATGACAAGCCATTGGGTAGGATTCACAAACCTGATCCCTGGCTTTCCAAATTCCTATCACGGTATAGAAAAACCCAT CACATTGAACCACGTACCATTAGCCAGGATGAGATCCTTGAACGCTGCTTATATTCACTTATCAATGAAGCATTCCGTATCTTGGGAGAA GGGATAGCTGCTAGCCCAGAGCACATTGATGTTGTCTATTTACATGGATATGGATGGCCAAGGCACAAGGGCGGGCCCATGTTCTATGCT TCCACAGTTGGGTTGCCCACAGTTCTAGAGAAATTGCAGAAATATTACAGGCAGAACCCTGATATTCCCCAACTGGAGCCAAGTGACTAT CTAAAAAAACTGGCTTCTCAGGGAAACCCTCCCCTGAAAGAATGGCAAAGCTTGGCAGGCTCCCCTAGCAGTAAATTGTGATTCAGTCTT CCAGATTATGCCTCACATGCTAGCATCAGGTAATGCTGACTGAATTTCAGTGAAATTAAATCAAAAATCCAAAGTAAGATTGTTCTGAAA TACAAAGCAAAATAAATAATCATTAGAATCTTCTGTGTAACGACTCTAATGGTCAAATCTTTAGGAATGTGCTTCCTATGCCTCTGAATC >61523_61523_2_OPA1-EHHADH_OPA1_chr3_193361894_ENST00000361150_EHHADH_chr3_184947331_ENST00000456310_length(amino acids)=1151AA_BP=545 MSTGACQALAEVHAPLGGPRPRLCALAAEGHFLGHSWTGSRAGAHTGAPAWPSRRLRDLPAGGMWRLRRAAVACEVCQSLVKHSSGIKGS LPLQKLHLVSRSIYHSHHPTLKLQRPQLRTSFQQFSSLTNLPLRKLKFSPIKYGYQPRRNFWPARLATRLLKLRYLILGSAVGGGYTAKK TFDQWKDMIPDLSEYKWIVPDIVWEIDEYIDFGSPEETAFRATDRGSESDKHFRKGLLGELILLQQQIQEHEEEARRAAGQYSTSYAQQK RKVSDKEKIDQLQEELLHTQLKYQRILERLEKENKELRKLVLQKDDKGIHHRKLKKSLIDMYSEVLDVLSDYDASYNTQDHLPRVVVVGD QSAGKTSVLEMIAQARIFPRGSGEMMTRSPVKVTLSEGPHHVALFKDSSREFDLTKEEDLAALRHEIELRMRKNVKEGCTVSPETISLNV KGPGLQRMVLVDLPGVINTVTSGMAPDTKETIFSISKAYMQNPNAIILCIQDGSVDAERSIVTDLVSQMDPHGRRTIFVLTKVDLAEKNV ASPSRAQVGLPEVTLGLLPGARGTQLLPRLTGVPAALDLITSGRRILADEALKLGILDKVVNSDPVEEAIRFAQRVSDQPLESRRLCNKP IQSLPNMDSIFSEALLKMRRQHPGCLAQEACVRAVQAAVQYPYEVGIKKEEELFLYLLQSGQARALQYAFFAERKANKWSTPSGASWKTA SARPVSSVGVVGLGTMGRGIVISFARARIPVIAVDSDKNQLATANKMITSVLEKEASKMQQSGHPWSGPKPRLTSSVKELGGVDLVIEAV FEEMSLKKQVFAELSAVCKPEAFLCTNTSALDVDEIASSTDRPHLVIGTHFFSPAHVMKLLEVIPSQYSSPTTIATVMNLSKKIKKIGVV VGNCFGFVGNRMLNPYYNQAYFLLEEGSKPEEVDQVLEEFGFKMGPFRVSDLAGLDVGWKSRKGQGLTGPTLLPGTPARKRGNRRYCPIP DVLCELGRFGQKTGKGWYQYDKPLGRIHKPDPWLSKFLSRYRKTHHIEPRTISQDEILERCLYSLINEAFRILGEGIAASPEHIDVVYLH -------------------------------------------------------------- >61523_61523_3_OPA1-EHHADH_OPA1_chr3_193361894_ENST00000361510_EHHADH_chr3_184947331_ENST00000231887_length(transcript)=5265nt_BP=1842nt GTGCTGCCCGCCTAGAAAGGGTGAAGTGGTTGTTTCCGTGACGGACTGAGTACGGGTGCCTGTCAGGCTCTTGCGGAAGTCCATGCGCCA TTGGGAGGGCCTCGGCCGCGGCTCTGTGCCCTTGCTGCTGAGGGCCACTTCCTGGGTCATTCCTGGACCGGGAGCCGGGCTGGGGCTCAC ACGGGGGCTCCCGCGTGGCCGTCTCGGCGCCTGCGTGACCTCCCCGCCGGCGGGATGTGGCGACTACGTCGGGCCGCTGTGGCCTGTGAG GTCTGCCAGTCTTTAGTGAAACACAGCTCTGGAATAAAAGGAAGTTTACCACTACAAAAACTACATCTGGTTTCACGAAGCATTTATCAT TCACATCATCCTACCTTAAAGCTTCAACGACCCCAATTAAGGACATCCTTTCAGCAGTTCTCTTCTCTGACAAACCTTCCTTTACGTAAA CTGAAATTCTCTCCAATTAAATATGGCTACCAGCCTCGCAGGAATTTTTGGCCAGCAAGATTAGCTACGAGACTCTTAAAACTTCGCTAT CTCATACTAGGATCGGCTGTTGGGGGTGGCTACACAGCCAAAAAGACTTTTGATCAGTGGAAAGATATGATACCGGACCTTAGTGAATAT AAATGGATTGTGCCTGACATTGTGTGGGAAATTGATGAGTATATCGATTTTGAGAAAATTAGAAAAGCCCTTCCTAGTTCAGAAGACCTT GTAAAGTTAGCACCAGACTTTGACAAGATTGTTGAAAGCCTTAGCTTATTGAAGGACTTTTTTACCTCAGGTCACAAATTGGTTAGTGAA GTCATAGGAGCTTCTGACCTACTTCTCTTGTTAGGTTCTCCGGAAGAAACGGCGTTTAGAGCAACAGATCGTGGATCTGAAAGTGACAAG CATTTTAGAAAGGGTCTGCTTGGTGAGCTCATTCTCTTACAACAACAAATTCAAGAGCATGAAGAGGAAGCGCGCAGAGCCGCTGGCCAA TATAGCACGAGCTATGCCCAACAGAAGCGCAAGGTGTCAGACAAAGAGAAAATTGACCAACTTCAGGAAGAACTTCTGCACACTCAGTTG AAGTATCAGAGAATCTTGGAACGATTAGAAAAGGAGAACAAAGAATTGAGAAAATTAGTATTGCAGAAAGATGACAAAGGCATTCATCAT AGAAAGCTTAAGAAATCTTTGATTGACATGTATTCTGAAGTTCTTGATGTTCTCTCTGATTATGATGCCAGTTATAATACGCAAGATCAT CTGCCACGGGTTGTTGTGGTTGGAGATCAGAGTGCTGGAAAGACTAGTGTGTTGGAAATGATTGCCCAAGCTCGAATATTCCCAAGAGGA TCTGGGGAGATGATGACACGTTCTCCAGTTAAGGTGACTCTGAGTGAAGGTCCTCACCATGTGGCCCTATTTAAAGATAGTTCTCGGGAG TTTGATCTTACCAAAGAAGAAGATCTTGCAGCATTAAGACATGAAATAGAACTTCGAATGAGGAAAAATGTGAAAGAAGGCTGTACCGTT AGCCCTGAGACCATATCCTTAAATGTAAAAGGCCCTGGACTACAGAGGATGGTGCTTGTTGACTTACCAGGTGTGATTAATACTGTGACA TCAGGCATGGCTCCTGACACAAAGGAAACTATTTTCAGTATCAGCAAAGCTTACATGCAGAATCCTAATGCCATCATACTGTGTATTCAA GATGGATCTGTGGATGCTGAACGCAGTATTGTTACAGACTTGGTCAGTCAAATGGACCCTCATGGAAGGAGAACCATATTCGTTTTGACC AAAGTAGACCTGGCAGAGAAAAATGTAGCCAGTCCAAGCAGGGCTCAAGTTGGCTTACCAGAAGTTACACTGGGACTTCTCCCTGGTGCA AGAGGAACCCAGCTTCTCCCCAGACTCACTGGAGTTCCTGCTGCACTTGACTTAATTACCTCAGGAAGACGTATTTTAGCAGATGAAGCA CTCAAGCTGGGCATTCTAGATAAAGTTGTAAACTCAGACCCGGTTGAAGAAGCAATCAGATTTGCTCAGAGAGTTTCAGATCAACCTCTA GAATCCCGTAGACTCTGCAACAAGCCAATTCAGAGCTTGCCCAACATGGACAGCATTTTTAGTGAGGCCCTCTTGAAGATGCGGAGGCAG CACCCTGGGTGTCTTGCACAGGAGGCTTGTGTCCGTGCAGTCCAGGCTGCTGTGCAGTATCCCTATGAAGTGGGCATCAAGAAGGAGGAG GAGCTGTTTCTATATCTTTTGCAATCAGGGCAGGCTAGAGCCCTGCAATATGCTTTCTTCGCTGAAAGGAAAGCAAATAAGTGGTCAACT CCCTCCGGAGCATCGTGGAAAACAGCATCAGCGCGGCCTGTCTCCTCAGTTGGTGTTGTTGGCTTGGGAACAATGGGCCGAGGCATTGTC ATTTCTTTTGCAAGGGCCAGGATTCCTGTGATTGCTGTAGACTCGGACAAAAACCAGCTAGCAACTGCAAACAAGATGATAACCTCTGTC TTGGAAAAAGAAGCCTCCAAAATGCAACAGAGCGGCCACCCTTGGTCAGGACCAAAACCCAGGTTAACTTCATCTGTGAAGGAGCTTGGT GGTGTAGATTTAGTCATTGAAGCAGTATTTGAGGAAATGAGCCTGAAGAAGCAGGTCTTTGCTGAACTCTCAGCTGTGTGCAAACCAGAA GCATTTTTGTGCACTAATACTTCAGCCCTGGATGTTGATGAGATTGCTTCTTCCACTGATCGTCCTCACTTGGTCATTGGCACCCACTTC TTTTCGCCAGCTCATGTCATGAAGTTGTTAGAGGTTATTCCCAGCCAATACTCTTCCCCCACTACCATTGCCACTGTTATGAACTTATCA AAAAAGATTAAAAAGATTGGAGTCGTTGTAGGCAACTGTTTTGGATTTGTGGGGAATCGAATGTTGAATCCTTACTACAATCAGGCATAT TTCTTGTTAGAAGAAGGCAGCAAACCAGAGGAGGTAGATCAGGTGCTGGAAGAGTTTGGTTTTAAAATGGGACCTTTTAGAGTGTCTGAT CTTGCTGGGTTGGATGTGGGCTGGAAATCTAGAAAGGGGCAAGGTCTTACTGGACCTACATTGCTTCCAGGAACTCCTGCCCGAAAAAGG GGTAATAGGAGGTACTGCCCAATTCCTGATGTGCTCTGTGAATTAGGACGATTTGGCCAGAAGACAGGTAAGGGTTGGTATCAATATGAC AAGCCATTGGGTAGGATTCACAAACCTGATCCCTGGCTTTCCAAATTCCTATCACGGTATAGAAAAACCCATCACATTGAACCACGTACC ATTAGCCAGGATGAGATCCTTGAACGCTGCTTATATTCACTTATCAATGAAGCATTCCGTATCTTGGGAGAAGGGATAGCTGCTAGCCCA GAGCACATTGATGTTGTCTATTTACATGGATATGGATGGCCAAGGCACAAGGGCGGGCCCATGTTCTATGCTTCCACAGTTGGGTTGCCC ACAGTTCTAGAGAAATTGCAGAAATATTACAGGCAGAACCCTGATATTCCCCAACTGGAGCCAAGTGACTATCTAAAAAAACTGGCTTCT CAGGGAAACCCTCCCCTGAAAGAATGGCAAAGCTTGGCAGGCTCCCCTAGCAGTAAATTGTGATTCAGTCTTCCAGATTATGCCTCACAT GCTAGCATCAGGTAATGCTGACTGAATTTCAGTGAAATTAAATCAAAAATCCAAAGTAAGATTGTTCTGAAATACAAAGCAAAATAAATA ATCATTAGAATCTTCTGTGTAACGACTCTAATGGTCAAATCTTTAGGAATGTGCTTCCTATGCCTCTGAATCTGTCCTTATCAGATAAAT TCAATGCATGAACTTGTGTGAATATAATACCATAATAGCTAATGAAAGAGGCTCAGGCATAAGTTGAGATTCTCAAATGCTTTTATCATT GGATAAATGTGTCATCAATTAATAAATGATAAATGCAGCTAAGTCATACATTCATTTTGACTCCTTTCAATGTCACACACATAGTATTGA TCAGAAATCTTATGAATCATACATACACTCAACAAACATTAAAGTTGTAGGAAAAAGACAGTTGGAAATTGGTAAGGGAACTGAGTACTT CAAACCAGCACAGGGAACTTAGGTTAGTGTGGCAAGCCTTTCCTCTTCTGGTCTTTCCTCTTCTGTTTATGGAGAAATAATAGAAAGTAG TAAGTCGTTAACTTAGTGTAAGAAGGGTCTTAGAGAACATCTAACCTTCTAGGATTTCCCAATTCTGTGATAGAGTAATGACACCAGTTT TCCTGTCATGACAAGCCTCTGTGATGTTACATATGGAAATGGTTGAATCTTGAAAAATCTAAAATTGTTGCAAAACATATTTTGTATGAT TTTGTTGTAAGAGTTCTTCTCTTTTTACTTTTTGCCTTGTGTAGTTAAAAATTAAGGGGCTGGTCAATACAAAAACTTGTACACAAATAT TTATAGCAGAATTATTCATAATGGCCAAAAGCTGAATACAACCCAAATGTCTATGAACTAATGAATAGATAAACCAAATCTGGTATATCC ATACAATGGACTATATTATTCAGCCATAAAAAGAAATAAAGGGCCAGGCACAGTGGCTCACACCTGTAATCCCAGCACTTTGGGAGGCTG AGGCAGGAGGATTGTTTGAGGCCAGAAATTTGAGACCAGCCTGGGCAACATAGCAAAACCCTGTCTCTACAAAAAATACTTTCCGTACAT TAGTGGTTGCCTAAGGCTAGAATTGGGGGTGATGAATGGGGAGTACAGGATTCATCTAATGGGTACAGGATTTCTTTATGGTTCATGAAA ATGGTCTAAACTTATTGTGGTAATGGTCACATAACAATATATTAAAAACCATTGAGTTGTATATTTTAAGTGGGTGAATTATATGGTATG TGAATTATATCTCAATAAAGTTGTTAGTAAATAAATGGGGCTGAAGATGTTATCCTTCATTGTGGTGTAAATGAACTTTCACAATATTTT CACCTGTGAACCCAAATAAAATGATTAAAGTTCTGATGGAAAAATCTTGAATGGAGTATAAGTTTTCCGTTGTTAAAAAGCAAACAAAAA ACCAACAAAAAATCCAAGTGTGCCTTGAATTGTACAGAGCACAATTATTATGTTTGAAATGTGTACTACTTAATTTTATATAATTTGGTT >61523_61523_3_OPA1-EHHADH_OPA1_chr3_193361894_ENST00000361510_EHHADH_chr3_184947331_ENST00000231887_length(amino acids)=1205AA_BP=599 MSTGACQALAEVHAPLGGPRPRLCALAAEGHFLGHSWTGSRAGAHTGAPAWPSRRLRDLPAGGMWRLRRAAVACEVCQSLVKHSSGIKGS LPLQKLHLVSRSIYHSHHPTLKLQRPQLRTSFQQFSSLTNLPLRKLKFSPIKYGYQPRRNFWPARLATRLLKLRYLILGSAVGGGYTAKK TFDQWKDMIPDLSEYKWIVPDIVWEIDEYIDFEKIRKALPSSEDLVKLAPDFDKIVESLSLLKDFFTSGHKLVSEVIGASDLLLLLGSPE ETAFRATDRGSESDKHFRKGLLGELILLQQQIQEHEEEARRAAGQYSTSYAQQKRKVSDKEKIDQLQEELLHTQLKYQRILERLEKENKE LRKLVLQKDDKGIHHRKLKKSLIDMYSEVLDVLSDYDASYNTQDHLPRVVVVGDQSAGKTSVLEMIAQARIFPRGSGEMMTRSPVKVTLS EGPHHVALFKDSSREFDLTKEEDLAALRHEIELRMRKNVKEGCTVSPETISLNVKGPGLQRMVLVDLPGVINTVTSGMAPDTKETIFSIS KAYMQNPNAIILCIQDGSVDAERSIVTDLVSQMDPHGRRTIFVLTKVDLAEKNVASPSRAQVGLPEVTLGLLPGARGTQLLPRLTGVPAA LDLITSGRRILADEALKLGILDKVVNSDPVEEAIRFAQRVSDQPLESRRLCNKPIQSLPNMDSIFSEALLKMRRQHPGCLAQEACVRAVQ AAVQYPYEVGIKKEEELFLYLLQSGQARALQYAFFAERKANKWSTPSGASWKTASARPVSSVGVVGLGTMGRGIVISFARARIPVIAVDS DKNQLATANKMITSVLEKEASKMQQSGHPWSGPKPRLTSSVKELGGVDLVIEAVFEEMSLKKQVFAELSAVCKPEAFLCTNTSALDVDEI ASSTDRPHLVIGTHFFSPAHVMKLLEVIPSQYSSPTTIATVMNLSKKIKKIGVVVGNCFGFVGNRMLNPYYNQAYFLLEEGSKPEEVDQV LEEFGFKMGPFRVSDLAGLDVGWKSRKGQGLTGPTLLPGTPARKRGNRRYCPIPDVLCELGRFGQKTGKGWYQYDKPLGRIHKPDPWLSK FLSRYRKTHHIEPRTISQDEILERCLYSLINEAFRILGEGIAASPEHIDVVYLHGYGWPRHKGGPMFYASTVGLPTVLEKLQKYYRQNPD -------------------------------------------------------------- >61523_61523_4_OPA1-EHHADH_OPA1_chr3_193361894_ENST00000361510_EHHADH_chr3_184947331_ENST00000456310_length(transcript)=3919nt_BP=1842nt GTGCTGCCCGCCTAGAAAGGGTGAAGTGGTTGTTTCCGTGACGGACTGAGTACGGGTGCCTGTCAGGCTCTTGCGGAAGTCCATGCGCCA TTGGGAGGGCCTCGGCCGCGGCTCTGTGCCCTTGCTGCTGAGGGCCACTTCCTGGGTCATTCCTGGACCGGGAGCCGGGCTGGGGCTCAC ACGGGGGCTCCCGCGTGGCCGTCTCGGCGCCTGCGTGACCTCCCCGCCGGCGGGATGTGGCGACTACGTCGGGCCGCTGTGGCCTGTGAG GTCTGCCAGTCTTTAGTGAAACACAGCTCTGGAATAAAAGGAAGTTTACCACTACAAAAACTACATCTGGTTTCACGAAGCATTTATCAT TCACATCATCCTACCTTAAAGCTTCAACGACCCCAATTAAGGACATCCTTTCAGCAGTTCTCTTCTCTGACAAACCTTCCTTTACGTAAA CTGAAATTCTCTCCAATTAAATATGGCTACCAGCCTCGCAGGAATTTTTGGCCAGCAAGATTAGCTACGAGACTCTTAAAACTTCGCTAT CTCATACTAGGATCGGCTGTTGGGGGTGGCTACACAGCCAAAAAGACTTTTGATCAGTGGAAAGATATGATACCGGACCTTAGTGAATAT AAATGGATTGTGCCTGACATTGTGTGGGAAATTGATGAGTATATCGATTTTGAGAAAATTAGAAAAGCCCTTCCTAGTTCAGAAGACCTT GTAAAGTTAGCACCAGACTTTGACAAGATTGTTGAAAGCCTTAGCTTATTGAAGGACTTTTTTACCTCAGGTCACAAATTGGTTAGTGAA GTCATAGGAGCTTCTGACCTACTTCTCTTGTTAGGTTCTCCGGAAGAAACGGCGTTTAGAGCAACAGATCGTGGATCTGAAAGTGACAAG CATTTTAGAAAGGGTCTGCTTGGTGAGCTCATTCTCTTACAACAACAAATTCAAGAGCATGAAGAGGAAGCGCGCAGAGCCGCTGGCCAA TATAGCACGAGCTATGCCCAACAGAAGCGCAAGGTGTCAGACAAAGAGAAAATTGACCAACTTCAGGAAGAACTTCTGCACACTCAGTTG AAGTATCAGAGAATCTTGGAACGATTAGAAAAGGAGAACAAAGAATTGAGAAAATTAGTATTGCAGAAAGATGACAAAGGCATTCATCAT AGAAAGCTTAAGAAATCTTTGATTGACATGTATTCTGAAGTTCTTGATGTTCTCTCTGATTATGATGCCAGTTATAATACGCAAGATCAT CTGCCACGGGTTGTTGTGGTTGGAGATCAGAGTGCTGGAAAGACTAGTGTGTTGGAAATGATTGCCCAAGCTCGAATATTCCCAAGAGGA TCTGGGGAGATGATGACACGTTCTCCAGTTAAGGTGACTCTGAGTGAAGGTCCTCACCATGTGGCCCTATTTAAAGATAGTTCTCGGGAG TTTGATCTTACCAAAGAAGAAGATCTTGCAGCATTAAGACATGAAATAGAACTTCGAATGAGGAAAAATGTGAAAGAAGGCTGTACCGTT AGCCCTGAGACCATATCCTTAAATGTAAAAGGCCCTGGACTACAGAGGATGGTGCTTGTTGACTTACCAGGTGTGATTAATACTGTGACA TCAGGCATGGCTCCTGACACAAAGGAAACTATTTTCAGTATCAGCAAAGCTTACATGCAGAATCCTAATGCCATCATACTGTGTATTCAA GATGGATCTGTGGATGCTGAACGCAGTATTGTTACAGACTTGGTCAGTCAAATGGACCCTCATGGAAGGAGAACCATATTCGTTTTGACC AAAGTAGACCTGGCAGAGAAAAATGTAGCCAGTCCAAGCAGGGCTCAAGTTGGCTTACCAGAAGTTACACTGGGACTTCTCCCTGGTGCA AGAGGAACCCAGCTTCTCCCCAGACTCACTGGAGTTCCTGCTGCACTTGACTTAATTACCTCAGGAAGACGTATTTTAGCAGATGAAGCA CTCAAGCTGGGCATTCTAGATAAAGTTGTAAACTCAGACCCGGTTGAAGAAGCAATCAGATTTGCTCAGAGAGTTTCAGATCAACCTCTA GAATCCCGTAGACTCTGCAACAAGCCAATTCAGAGCTTGCCCAACATGGACAGCATTTTTAGTGAGGCCCTCTTGAAGATGCGGAGGCAG CACCCTGGGTGTCTTGCACAGGAGGCTTGTGTCCGTGCAGTCCAGGCTGCTGTGCAGTATCCCTATGAAGTGGGCATCAAGAAGGAGGAG GAGCTGTTTCTATATCTTTTGCAATCAGGGCAGGCTAGAGCCCTGCAATATGCTTTCTTCGCTGAAAGGAAAGCAAATAAGTGGTCAACT CCCTCCGGAGCATCGTGGAAAACAGCATCAGCGCGGCCTGTCTCCTCAGTTGGTGTTGTTGGCTTGGGAACAATGGGCCGAGGCATTGTC ATTTCTTTTGCAAGGGCCAGGATTCCTGTGATTGCTGTAGACTCGGACAAAAACCAGCTAGCAACTGCAAACAAGATGATAACCTCTGTC TTGGAAAAAGAAGCCTCCAAAATGCAACAGAGCGGCCACCCTTGGTCAGGACCAAAACCCAGGTTAACTTCATCTGTGAAGGAGCTTGGT GGTGTAGATTTAGTCATTGAAGCAGTATTTGAGGAAATGAGCCTGAAGAAGCAGGTCTTTGCTGAACTCTCAGCTGTGTGCAAACCAGAA GCATTTTTGTGCACTAATACTTCAGCCCTGGATGTTGATGAGATTGCTTCTTCCACTGATCGTCCTCACTTGGTCATTGGCACCCACTTC TTTTCGCCAGCTCATGTCATGAAGTTGTTAGAGGTTATTCCCAGCCAATACTCTTCCCCCACTACCATTGCCACTGTTATGAACTTATCA AAAAAGATTAAAAAGATTGGAGTCGTTGTAGGCAACTGTTTTGGATTTGTGGGGAATCGAATGTTGAATCCTTACTACAATCAGGCATAT TTCTTGTTAGAAGAAGGCAGCAAACCAGAGGAGGTAGATCAGGTGCTGGAAGAGTTTGGTTTTAAAATGGGACCTTTTAGAGTGTCTGAT CTTGCTGGGTTGGATGTGGGCTGGAAATCTAGAAAGGGGCAAGGTCTTACTGGACCTACATTGCTTCCAGGAACTCCTGCCCGAAAAAGG GGTAATAGGAGGTACTGCCCAATTCCTGATGTGCTCTGTGAATTAGGACGATTTGGCCAGAAGACAGGTAAGGGTTGGTATCAATATGAC AAGCCATTGGGTAGGATTCACAAACCTGATCCCTGGCTTTCCAAATTCCTATCACGGTATAGAAAAACCCATCACATTGAACCACGTACC ATTAGCCAGGATGAGATCCTTGAACGCTGCTTATATTCACTTATCAATGAAGCATTCCGTATCTTGGGAGAAGGGATAGCTGCTAGCCCA GAGCACATTGATGTTGTCTATTTACATGGATATGGATGGCCAAGGCACAAGGGCGGGCCCATGTTCTATGCTTCCACAGTTGGGTTGCCC ACAGTTCTAGAGAAATTGCAGAAATATTACAGGCAGAACCCTGATATTCCCCAACTGGAGCCAAGTGACTATCTAAAAAAACTGGCTTCT CAGGGAAACCCTCCCCTGAAAGAATGGCAAAGCTTGGCAGGCTCCCCTAGCAGTAAATTGTGATTCAGTCTTCCAGATTATGCCTCACAT GCTAGCATCAGGTAATGCTGACTGAATTTCAGTGAAATTAAATCAAAAATCCAAAGTAAGATTGTTCTGAAATACAAAGCAAAATAAATA ATCATTAGAATCTTCTGTGTAACGACTCTAATGGTCAAATCTTTAGGAATGTGCTTCCTATGCCTCTGAATCTGTCCTTATCAGATAAAT >61523_61523_4_OPA1-EHHADH_OPA1_chr3_193361894_ENST00000361510_EHHADH_chr3_184947331_ENST00000456310_length(amino acids)=1205AA_BP=599 MSTGACQALAEVHAPLGGPRPRLCALAAEGHFLGHSWTGSRAGAHTGAPAWPSRRLRDLPAGGMWRLRRAAVACEVCQSLVKHSSGIKGS LPLQKLHLVSRSIYHSHHPTLKLQRPQLRTSFQQFSSLTNLPLRKLKFSPIKYGYQPRRNFWPARLATRLLKLRYLILGSAVGGGYTAKK TFDQWKDMIPDLSEYKWIVPDIVWEIDEYIDFEKIRKALPSSEDLVKLAPDFDKIVESLSLLKDFFTSGHKLVSEVIGASDLLLLLGSPE ETAFRATDRGSESDKHFRKGLLGELILLQQQIQEHEEEARRAAGQYSTSYAQQKRKVSDKEKIDQLQEELLHTQLKYQRILERLEKENKE LRKLVLQKDDKGIHHRKLKKSLIDMYSEVLDVLSDYDASYNTQDHLPRVVVVGDQSAGKTSVLEMIAQARIFPRGSGEMMTRSPVKVTLS EGPHHVALFKDSSREFDLTKEEDLAALRHEIELRMRKNVKEGCTVSPETISLNVKGPGLQRMVLVDLPGVINTVTSGMAPDTKETIFSIS KAYMQNPNAIILCIQDGSVDAERSIVTDLVSQMDPHGRRTIFVLTKVDLAEKNVASPSRAQVGLPEVTLGLLPGARGTQLLPRLTGVPAA LDLITSGRRILADEALKLGILDKVVNSDPVEEAIRFAQRVSDQPLESRRLCNKPIQSLPNMDSIFSEALLKMRRQHPGCLAQEACVRAVQ AAVQYPYEVGIKKEEELFLYLLQSGQARALQYAFFAERKANKWSTPSGASWKTASARPVSSVGVVGLGTMGRGIVISFARARIPVIAVDS DKNQLATANKMITSVLEKEASKMQQSGHPWSGPKPRLTSSVKELGGVDLVIEAVFEEMSLKKQVFAELSAVCKPEAFLCTNTSALDVDEI ASSTDRPHLVIGTHFFSPAHVMKLLEVIPSQYSSPTTIATVMNLSKKIKKIGVVVGNCFGFVGNRMLNPYYNQAYFLLEEGSKPEEVDQV LEEFGFKMGPFRVSDLAGLDVGWKSRKGQGLTGPTLLPGTPARKRGNRRYCPIPDVLCELGRFGQKTGKGWYQYDKPLGRIHKPDPWLSK FLSRYRKTHHIEPRTISQDEILERCLYSLINEAFRILGEGIAASPEHIDVVYLHGYGWPRHKGGPMFYASTVGLPTVLEKLQKYYRQNPD -------------------------------------------------------------- >61523_61523_5_OPA1-EHHADH_OPA1_chr3_193361894_ENST00000361715_EHHADH_chr3_184947331_ENST00000231887_length(transcript)=5157nt_BP=1734nt GTGCTGCCCGCCTAGAAAGGGTGAAGTGGTTGTTTCCGTGACGGACTGAGTACGGGTGCCTGTCAGGCTCTTGCGGAAGTCCATGCGCCA TTGGGAGGGCCTCGGCCGCGGCTCTGTGCCCTTGCTGCTGAGGGCCACTTCCTGGGTCATTCCTGGACCGGGAGCCGGGCTGGGGCTCAC ACGGGGGCTCCCGCGTGGCCGTCTCGGCGCCTGCGTGACCTCCCCGCCGGCGGGATGTGGCGACTACGTCGGGCCGCTGTGGCCTGTGAG GTCTGCCAGTCTTTAGTGAAACACAGCTCTGGAATAAAAGGAAGTTTACCACTACAAAAACTACATCTGGTTTCACGAAGCATTTATCAT TCACATCATCCTACCTTAAAGCTTCAACGACCCCAATTAAGGACATCCTTTCAGCAGTTCTCTTCTCTGACAAACCTTCCTTTACGTAAA CTGAAATTCTCTCCAATTAAATATGGCTACCAGCCTCGCAGGAATTTTTGGCCAGCAAGATTAGCTACGAGACTCTTAAAACTTCGCTAT CTCATACTAGGATCGGCTGTTGGGGGTGGCTACACAGCCAAAAAGACTTTTGATCAGTGGAAAGATATGATACCGGACCTTAGTGAATAT AAATGGATTGTGCCTGACATTGTGTGGGAAATTGATGAGTATATCGATTTTGGTCACAAATTGGTTAGTGAAGTCATAGGAGCTTCTGAC CTACTTCTCTTGTTAGGTTCTCCGGAAGAAACGGCGTTTAGAGCAACAGATCGTGGATCTGAAAGTGACAAGCATTTTAGAAAGGGTCTG CTTGGTGAGCTCATTCTCTTACAACAACAAATTCAAGAGCATGAAGAGGAAGCGCGCAGAGCCGCTGGCCAATATAGCACGAGCTATGCC CAACAGAAGCGCAAGGTGTCAGACAAAGAGAAAATTGACCAACTTCAGGAAGAACTTCTGCACACTCAGTTGAAGTATCAGAGAATCTTG GAACGATTAGAAAAGGAGAACAAAGAATTGAGAAAATTAGTATTGCAGAAAGATGACAAAGGCATTCATCATAGAAAGCTTAAGAAATCT TTGATTGACATGTATTCTGAAGTTCTTGATGTTCTCTCTGATTATGATGCCAGTTATAATACGCAAGATCATCTGCCACGGGTTGTTGTG GTTGGAGATCAGAGTGCTGGAAAGACTAGTGTGTTGGAAATGATTGCCCAAGCTCGAATATTCCCAAGAGGATCTGGGGAGATGATGACA CGTTCTCCAGTTAAGGTGACTCTGAGTGAAGGTCCTCACCATGTGGCCCTATTTAAAGATAGTTCTCGGGAGTTTGATCTTACCAAAGAA GAAGATCTTGCAGCATTAAGACATGAAATAGAACTTCGAATGAGGAAAAATGTGAAAGAAGGCTGTACCGTTAGCCCTGAGACCATATCC TTAAATGTAAAAGGCCCTGGACTACAGAGGATGGTGCTTGTTGACTTACCAGGTGTGATTAATACTGTGACATCAGGCATGGCTCCTGAC ACAAAGGAAACTATTTTCAGTATCAGCAAAGCTTACATGCAGAATCCTAATGCCATCATACTGTGTATTCAAGATGGATCTGTGGATGCT GAACGCAGTATTGTTACAGACTTGGTCAGTCAAATGGACCCTCATGGAAGGAGAACCATATTCGTTTTGACCAAAGTAGACCTGGCAGAG AAAAATGTAGCCAGTCCAAGCAGGGCTCAAGTTGGCTTACCAGAAGTTACACTGGGACTTCTCCCTGGTGCAAGAGGAACCCAGCTTCTC CCCAGACTCACTGGAGTTCCTGCTGCACTTGACTTAATTACCTCAGGAAGACGTATTTTAGCAGATGAAGCACTCAAGCTGGGCATTCTA GATAAAGTTGTAAACTCAGACCCGGTTGAAGAAGCAATCAGATTTGCTCAGAGAGTTTCAGATCAACCTCTAGAATCCCGTAGACTCTGC AACAAGCCAATTCAGAGCTTGCCCAACATGGACAGCATTTTTAGTGAGGCCCTCTTGAAGATGCGGAGGCAGCACCCTGGGTGTCTTGCA CAGGAGGCTTGTGTCCGTGCAGTCCAGGCTGCTGTGCAGTATCCCTATGAAGTGGGCATCAAGAAGGAGGAGGAGCTGTTTCTATATCTT TTGCAATCAGGGCAGGCTAGAGCCCTGCAATATGCTTTCTTCGCTGAAAGGAAAGCAAATAAGTGGTCAACTCCCTCCGGAGCATCGTGG AAAACAGCATCAGCGCGGCCTGTCTCCTCAGTTGGTGTTGTTGGCTTGGGAACAATGGGCCGAGGCATTGTCATTTCTTTTGCAAGGGCC AGGATTCCTGTGATTGCTGTAGACTCGGACAAAAACCAGCTAGCAACTGCAAACAAGATGATAACCTCTGTCTTGGAAAAAGAAGCCTCC AAAATGCAACAGAGCGGCCACCCTTGGTCAGGACCAAAACCCAGGTTAACTTCATCTGTGAAGGAGCTTGGTGGTGTAGATTTAGTCATT GAAGCAGTATTTGAGGAAATGAGCCTGAAGAAGCAGGTCTTTGCTGAACTCTCAGCTGTGTGCAAACCAGAAGCATTTTTGTGCACTAAT ACTTCAGCCCTGGATGTTGATGAGATTGCTTCTTCCACTGATCGTCCTCACTTGGTCATTGGCACCCACTTCTTTTCGCCAGCTCATGTC ATGAAGTTGTTAGAGGTTATTCCCAGCCAATACTCTTCCCCCACTACCATTGCCACTGTTATGAACTTATCAAAAAAGATTAAAAAGATT GGAGTCGTTGTAGGCAACTGTTTTGGATTTGTGGGGAATCGAATGTTGAATCCTTACTACAATCAGGCATATTTCTTGTTAGAAGAAGGC AGCAAACCAGAGGAGGTAGATCAGGTGCTGGAAGAGTTTGGTTTTAAAATGGGACCTTTTAGAGTGTCTGATCTTGCTGGGTTGGATGTG GGCTGGAAATCTAGAAAGGGGCAAGGTCTTACTGGACCTACATTGCTTCCAGGAACTCCTGCCCGAAAAAGGGGTAATAGGAGGTACTGC CCAATTCCTGATGTGCTCTGTGAATTAGGACGATTTGGCCAGAAGACAGGTAAGGGTTGGTATCAATATGACAAGCCATTGGGTAGGATT CACAAACCTGATCCCTGGCTTTCCAAATTCCTATCACGGTATAGAAAAACCCATCACATTGAACCACGTACCATTAGCCAGGATGAGATC CTTGAACGCTGCTTATATTCACTTATCAATGAAGCATTCCGTATCTTGGGAGAAGGGATAGCTGCTAGCCCAGAGCACATTGATGTTGTC TATTTACATGGATATGGATGGCCAAGGCACAAGGGCGGGCCCATGTTCTATGCTTCCACAGTTGGGTTGCCCACAGTTCTAGAGAAATTG CAGAAATATTACAGGCAGAACCCTGATATTCCCCAACTGGAGCCAAGTGACTATCTAAAAAAACTGGCTTCTCAGGGAAACCCTCCCCTG AAAGAATGGCAAAGCTTGGCAGGCTCCCCTAGCAGTAAATTGTGATTCAGTCTTCCAGATTATGCCTCACATGCTAGCATCAGGTAATGC TGACTGAATTTCAGTGAAATTAAATCAAAAATCCAAAGTAAGATTGTTCTGAAATACAAAGCAAAATAAATAATCATTAGAATCTTCTGT GTAACGACTCTAATGGTCAAATCTTTAGGAATGTGCTTCCTATGCCTCTGAATCTGTCCTTATCAGATAAATTCAATGCATGAACTTGTG TGAATATAATACCATAATAGCTAATGAAAGAGGCTCAGGCATAAGTTGAGATTCTCAAATGCTTTTATCATTGGATAAATGTGTCATCAA TTAATAAATGATAAATGCAGCTAAGTCATACATTCATTTTGACTCCTTTCAATGTCACACACATAGTATTGATCAGAAATCTTATGAATC ATACATACACTCAACAAACATTAAAGTTGTAGGAAAAAGACAGTTGGAAATTGGTAAGGGAACTGAGTACTTCAAACCAGCACAGGGAAC TTAGGTTAGTGTGGCAAGCCTTTCCTCTTCTGGTCTTTCCTCTTCTGTTTATGGAGAAATAATAGAAAGTAGTAAGTCGTTAACTTAGTG TAAGAAGGGTCTTAGAGAACATCTAACCTTCTAGGATTTCCCAATTCTGTGATAGAGTAATGACACCAGTTTTCCTGTCATGACAAGCCT CTGTGATGTTACATATGGAAATGGTTGAATCTTGAAAAATCTAAAATTGTTGCAAAACATATTTTGTATGATTTTGTTGTAAGAGTTCTT CTCTTTTTACTTTTTGCCTTGTGTAGTTAAAAATTAAGGGGCTGGTCAATACAAAAACTTGTACACAAATATTTATAGCAGAATTATTCA TAATGGCCAAAAGCTGAATACAACCCAAATGTCTATGAACTAATGAATAGATAAACCAAATCTGGTATATCCATACAATGGACTATATTA TTCAGCCATAAAAAGAAATAAAGGGCCAGGCACAGTGGCTCACACCTGTAATCCCAGCACTTTGGGAGGCTGAGGCAGGAGGATTGTTTG AGGCCAGAAATTTGAGACCAGCCTGGGCAACATAGCAAAACCCTGTCTCTACAAAAAATACTTTCCGTACATTAGTGGTTGCCTAAGGCT AGAATTGGGGGTGATGAATGGGGAGTACAGGATTCATCTAATGGGTACAGGATTTCTTTATGGTTCATGAAAATGGTCTAAACTTATTGT GGTAATGGTCACATAACAATATATTAAAAACCATTGAGTTGTATATTTTAAGTGGGTGAATTATATGGTATGTGAATTATATCTCAATAA AGTTGTTAGTAAATAAATGGGGCTGAAGATGTTATCCTTCATTGTGGTGTAAATGAACTTTCACAATATTTTCACCTGTGAACCCAAATA AAATGATTAAAGTTCTGATGGAAAAATCTTGAATGGAGTATAAGTTTTCCGTTGTTAAAAAGCAAACAAAAAACCAACAAAAAATCCAAG TGTGCCTTGAATTGTACAGAGCACAATTATTATGTTTGAAATGTGTACTACTTAATTTTATATAATTTGGTTTGTGAAATTAAAGACATC >61523_61523_5_OPA1-EHHADH_OPA1_chr3_193361894_ENST00000361715_EHHADH_chr3_184947331_ENST00000231887_length(amino acids)=1169AA_BP=563 MSTGACQALAEVHAPLGGPRPRLCALAAEGHFLGHSWTGSRAGAHTGAPAWPSRRLRDLPAGGMWRLRRAAVACEVCQSLVKHSSGIKGS LPLQKLHLVSRSIYHSHHPTLKLQRPQLRTSFQQFSSLTNLPLRKLKFSPIKYGYQPRRNFWPARLATRLLKLRYLILGSAVGGGYTAKK TFDQWKDMIPDLSEYKWIVPDIVWEIDEYIDFGHKLVSEVIGASDLLLLLGSPEETAFRATDRGSESDKHFRKGLLGELILLQQQIQEHE EEARRAAGQYSTSYAQQKRKVSDKEKIDQLQEELLHTQLKYQRILERLEKENKELRKLVLQKDDKGIHHRKLKKSLIDMYSEVLDVLSDY DASYNTQDHLPRVVVVGDQSAGKTSVLEMIAQARIFPRGSGEMMTRSPVKVTLSEGPHHVALFKDSSREFDLTKEEDLAALRHEIELRMR KNVKEGCTVSPETISLNVKGPGLQRMVLVDLPGVINTVTSGMAPDTKETIFSISKAYMQNPNAIILCIQDGSVDAERSIVTDLVSQMDPH GRRTIFVLTKVDLAEKNVASPSRAQVGLPEVTLGLLPGARGTQLLPRLTGVPAALDLITSGRRILADEALKLGILDKVVNSDPVEEAIRF AQRVSDQPLESRRLCNKPIQSLPNMDSIFSEALLKMRRQHPGCLAQEACVRAVQAAVQYPYEVGIKKEEELFLYLLQSGQARALQYAFFA ERKANKWSTPSGASWKTASARPVSSVGVVGLGTMGRGIVISFARARIPVIAVDSDKNQLATANKMITSVLEKEASKMQQSGHPWSGPKPR LTSSVKELGGVDLVIEAVFEEMSLKKQVFAELSAVCKPEAFLCTNTSALDVDEIASSTDRPHLVIGTHFFSPAHVMKLLEVIPSQYSSPT TIATVMNLSKKIKKIGVVVGNCFGFVGNRMLNPYYNQAYFLLEEGSKPEEVDQVLEEFGFKMGPFRVSDLAGLDVGWKSRKGQGLTGPTL LPGTPARKRGNRRYCPIPDVLCELGRFGQKTGKGWYQYDKPLGRIHKPDPWLSKFLSRYRKTHHIEPRTISQDEILERCLYSLINEAFRI -------------------------------------------------------------- >61523_61523_6_OPA1-EHHADH_OPA1_chr3_193361894_ENST00000361715_EHHADH_chr3_184947331_ENST00000456310_length(transcript)=3811nt_BP=1734nt GTGCTGCCCGCCTAGAAAGGGTGAAGTGGTTGTTTCCGTGACGGACTGAGTACGGGTGCCTGTCAGGCTCTTGCGGAAGTCCATGCGCCA TTGGGAGGGCCTCGGCCGCGGCTCTGTGCCCTTGCTGCTGAGGGCCACTTCCTGGGTCATTCCTGGACCGGGAGCCGGGCTGGGGCTCAC ACGGGGGCTCCCGCGTGGCCGTCTCGGCGCCTGCGTGACCTCCCCGCCGGCGGGATGTGGCGACTACGTCGGGCCGCTGTGGCCTGTGAG GTCTGCCAGTCTTTAGTGAAACACAGCTCTGGAATAAAAGGAAGTTTACCACTACAAAAACTACATCTGGTTTCACGAAGCATTTATCAT TCACATCATCCTACCTTAAAGCTTCAACGACCCCAATTAAGGACATCCTTTCAGCAGTTCTCTTCTCTGACAAACCTTCCTTTACGTAAA CTGAAATTCTCTCCAATTAAATATGGCTACCAGCCTCGCAGGAATTTTTGGCCAGCAAGATTAGCTACGAGACTCTTAAAACTTCGCTAT CTCATACTAGGATCGGCTGTTGGGGGTGGCTACACAGCCAAAAAGACTTTTGATCAGTGGAAAGATATGATACCGGACCTTAGTGAATAT AAATGGATTGTGCCTGACATTGTGTGGGAAATTGATGAGTATATCGATTTTGGTCACAAATTGGTTAGTGAAGTCATAGGAGCTTCTGAC CTACTTCTCTTGTTAGGTTCTCCGGAAGAAACGGCGTTTAGAGCAACAGATCGTGGATCTGAAAGTGACAAGCATTTTAGAAAGGGTCTG CTTGGTGAGCTCATTCTCTTACAACAACAAATTCAAGAGCATGAAGAGGAAGCGCGCAGAGCCGCTGGCCAATATAGCACGAGCTATGCC CAACAGAAGCGCAAGGTGTCAGACAAAGAGAAAATTGACCAACTTCAGGAAGAACTTCTGCACACTCAGTTGAAGTATCAGAGAATCTTG GAACGATTAGAAAAGGAGAACAAAGAATTGAGAAAATTAGTATTGCAGAAAGATGACAAAGGCATTCATCATAGAAAGCTTAAGAAATCT TTGATTGACATGTATTCTGAAGTTCTTGATGTTCTCTCTGATTATGATGCCAGTTATAATACGCAAGATCATCTGCCACGGGTTGTTGTG GTTGGAGATCAGAGTGCTGGAAAGACTAGTGTGTTGGAAATGATTGCCCAAGCTCGAATATTCCCAAGAGGATCTGGGGAGATGATGACA CGTTCTCCAGTTAAGGTGACTCTGAGTGAAGGTCCTCACCATGTGGCCCTATTTAAAGATAGTTCTCGGGAGTTTGATCTTACCAAAGAA GAAGATCTTGCAGCATTAAGACATGAAATAGAACTTCGAATGAGGAAAAATGTGAAAGAAGGCTGTACCGTTAGCCCTGAGACCATATCC TTAAATGTAAAAGGCCCTGGACTACAGAGGATGGTGCTTGTTGACTTACCAGGTGTGATTAATACTGTGACATCAGGCATGGCTCCTGAC ACAAAGGAAACTATTTTCAGTATCAGCAAAGCTTACATGCAGAATCCTAATGCCATCATACTGTGTATTCAAGATGGATCTGTGGATGCT GAACGCAGTATTGTTACAGACTTGGTCAGTCAAATGGACCCTCATGGAAGGAGAACCATATTCGTTTTGACCAAAGTAGACCTGGCAGAG AAAAATGTAGCCAGTCCAAGCAGGGCTCAAGTTGGCTTACCAGAAGTTACACTGGGACTTCTCCCTGGTGCAAGAGGAACCCAGCTTCTC CCCAGACTCACTGGAGTTCCTGCTGCACTTGACTTAATTACCTCAGGAAGACGTATTTTAGCAGATGAAGCACTCAAGCTGGGCATTCTA GATAAAGTTGTAAACTCAGACCCGGTTGAAGAAGCAATCAGATTTGCTCAGAGAGTTTCAGATCAACCTCTAGAATCCCGTAGACTCTGC AACAAGCCAATTCAGAGCTTGCCCAACATGGACAGCATTTTTAGTGAGGCCCTCTTGAAGATGCGGAGGCAGCACCCTGGGTGTCTTGCA CAGGAGGCTTGTGTCCGTGCAGTCCAGGCTGCTGTGCAGTATCCCTATGAAGTGGGCATCAAGAAGGAGGAGGAGCTGTTTCTATATCTT TTGCAATCAGGGCAGGCTAGAGCCCTGCAATATGCTTTCTTCGCTGAAAGGAAAGCAAATAAGTGGTCAACTCCCTCCGGAGCATCGTGG AAAACAGCATCAGCGCGGCCTGTCTCCTCAGTTGGTGTTGTTGGCTTGGGAACAATGGGCCGAGGCATTGTCATTTCTTTTGCAAGGGCC AGGATTCCTGTGATTGCTGTAGACTCGGACAAAAACCAGCTAGCAACTGCAAACAAGATGATAACCTCTGTCTTGGAAAAAGAAGCCTCC AAAATGCAACAGAGCGGCCACCCTTGGTCAGGACCAAAACCCAGGTTAACTTCATCTGTGAAGGAGCTTGGTGGTGTAGATTTAGTCATT GAAGCAGTATTTGAGGAAATGAGCCTGAAGAAGCAGGTCTTTGCTGAACTCTCAGCTGTGTGCAAACCAGAAGCATTTTTGTGCACTAAT ACTTCAGCCCTGGATGTTGATGAGATTGCTTCTTCCACTGATCGTCCTCACTTGGTCATTGGCACCCACTTCTTTTCGCCAGCTCATGTC ATGAAGTTGTTAGAGGTTATTCCCAGCCAATACTCTTCCCCCACTACCATTGCCACTGTTATGAACTTATCAAAAAAGATTAAAAAGATT GGAGTCGTTGTAGGCAACTGTTTTGGATTTGTGGGGAATCGAATGTTGAATCCTTACTACAATCAGGCATATTTCTTGTTAGAAGAAGGC AGCAAACCAGAGGAGGTAGATCAGGTGCTGGAAGAGTTTGGTTTTAAAATGGGACCTTTTAGAGTGTCTGATCTTGCTGGGTTGGATGTG GGCTGGAAATCTAGAAAGGGGCAAGGTCTTACTGGACCTACATTGCTTCCAGGAACTCCTGCCCGAAAAAGGGGTAATAGGAGGTACTGC CCAATTCCTGATGTGCTCTGTGAATTAGGACGATTTGGCCAGAAGACAGGTAAGGGTTGGTATCAATATGACAAGCCATTGGGTAGGATT CACAAACCTGATCCCTGGCTTTCCAAATTCCTATCACGGTATAGAAAAACCCATCACATTGAACCACGTACCATTAGCCAGGATGAGATC CTTGAACGCTGCTTATATTCACTTATCAATGAAGCATTCCGTATCTTGGGAGAAGGGATAGCTGCTAGCCCAGAGCACATTGATGTTGTC TATTTACATGGATATGGATGGCCAAGGCACAAGGGCGGGCCCATGTTCTATGCTTCCACAGTTGGGTTGCCCACAGTTCTAGAGAAATTG CAGAAATATTACAGGCAGAACCCTGATATTCCCCAACTGGAGCCAAGTGACTATCTAAAAAAACTGGCTTCTCAGGGAAACCCTCCCCTG AAAGAATGGCAAAGCTTGGCAGGCTCCCCTAGCAGTAAATTGTGATTCAGTCTTCCAGATTATGCCTCACATGCTAGCATCAGGTAATGC TGACTGAATTTCAGTGAAATTAAATCAAAAATCCAAAGTAAGATTGTTCTGAAATACAAAGCAAAATAAATAATCATTAGAATCTTCTGT GTAACGACTCTAATGGTCAAATCTTTAGGAATGTGCTTCCTATGCCTCTGAATCTGTCCTTATCAGATAAATTCAATGCATGAACTTGTG >61523_61523_6_OPA1-EHHADH_OPA1_chr3_193361894_ENST00000361715_EHHADH_chr3_184947331_ENST00000456310_length(amino acids)=1169AA_BP=563 MSTGACQALAEVHAPLGGPRPRLCALAAEGHFLGHSWTGSRAGAHTGAPAWPSRRLRDLPAGGMWRLRRAAVACEVCQSLVKHSSGIKGS LPLQKLHLVSRSIYHSHHPTLKLQRPQLRTSFQQFSSLTNLPLRKLKFSPIKYGYQPRRNFWPARLATRLLKLRYLILGSAVGGGYTAKK TFDQWKDMIPDLSEYKWIVPDIVWEIDEYIDFGHKLVSEVIGASDLLLLLGSPEETAFRATDRGSESDKHFRKGLLGELILLQQQIQEHE EEARRAAGQYSTSYAQQKRKVSDKEKIDQLQEELLHTQLKYQRILERLEKENKELRKLVLQKDDKGIHHRKLKKSLIDMYSEVLDVLSDY DASYNTQDHLPRVVVVGDQSAGKTSVLEMIAQARIFPRGSGEMMTRSPVKVTLSEGPHHVALFKDSSREFDLTKEEDLAALRHEIELRMR KNVKEGCTVSPETISLNVKGPGLQRMVLVDLPGVINTVTSGMAPDTKETIFSISKAYMQNPNAIILCIQDGSVDAERSIVTDLVSQMDPH GRRTIFVLTKVDLAEKNVASPSRAQVGLPEVTLGLLPGARGTQLLPRLTGVPAALDLITSGRRILADEALKLGILDKVVNSDPVEEAIRF AQRVSDQPLESRRLCNKPIQSLPNMDSIFSEALLKMRRQHPGCLAQEACVRAVQAAVQYPYEVGIKKEEELFLYLLQSGQARALQYAFFA ERKANKWSTPSGASWKTASARPVSSVGVVGLGTMGRGIVISFARARIPVIAVDSDKNQLATANKMITSVLEKEASKMQQSGHPWSGPKPR LTSSVKELGGVDLVIEAVFEEMSLKKQVFAELSAVCKPEAFLCTNTSALDVDEIASSTDRPHLVIGTHFFSPAHVMKLLEVIPSQYSSPT TIATVMNLSKKIKKIGVVVGNCFGFVGNRMLNPYYNQAYFLLEEGSKPEEVDQVLEEFGFKMGPFRVSDLAGLDVGWKSRKGQGLTGPTL LPGTPARKRGNRRYCPIPDVLCELGRFGQKTGKGWYQYDKPLGRIHKPDPWLSKFLSRYRKTHHIEPRTISQDEILERCLYSLINEAFRI -------------------------------------------------------------- >61523_61523_7_OPA1-EHHADH_OPA1_chr3_193361894_ENST00000361828_EHHADH_chr3_184947331_ENST00000231887_length(transcript)=5154nt_BP=1731nt GTGCTGCCCGCCTAGAAAGGGTGAAGTGGTTGTTTCCGTGACGGACTGAGTACGGGTGCCTGTCAGGCTCTTGCGGAAGTCCATGCGCCA TTGGGAGGGCCTCGGCCGCGGCTCTGTGCCCTTGCTGCTGAGGGCCACTTCCTGGGTCATTCCTGGACCGGGAGCCGGGCTGGGGCTCAC ACGGGGGCTCCCGCGTGGCCGTCTCGGCGCCTGCGTGACCTCCCCGCCGGCGGGATGTGGCGACTACGTCGGGCCGCTGTGGCCTGTGAG GTCTGCCAGTCTTTAGTGAAACACAGCTCTGGAATAAAAGGAAGTTTACCACTACAAAAACTACATCTGGTTTCACGAAGCATTTATCAT TCACATCATCCTACCTTAAAGCTTCAACGACCCCAATTAAGGACATCCTTTCAGCAGTTCTCTTCTCTGACAAACCTTCCTTTACGTAAA CTGAAATTCTCTCCAATTAAATATGGCTACCAGCCTCGCAGGAATTTTTGGCCAGCAAGATTAGCTACGAGACTCTTAAAACTTCGCTAT CTCATACTAGGATCGGCTGTTGGGGGTGGCTACACAGCCAAAAAGACTTTTGATCAGTGGAAAGATATGATACCGGACCTTAGTGAATAT AAATGGATTGTGCCTGACATTGTGTGGGAAATTGATGAGTATATCGATTTTGAGAAAATTAGAAAAGCCCTTCCTAGTTCAGAAGACCTT GTAAAGTTAGCACCAGACTTTGACAAGATTGTTGAAAGCCTTAGCTTATTGAAGGACTTTTTTACCTCAGGTCACAAATTGGTTAGTGAA GTCATAGGAGCTTCTGACCTACTTCTCTTGTTAGGTTCTCCGGAAGAAACGGCGTTTAGAGCAACAGATCGTGGATCTGAAAGTGACAAG CATTTTAGAAAGGTGTCAGACAAAGAGAAAATTGACCAACTTCAGGAAGAACTTCTGCACACTCAGTTGAAGTATCAGAGAATCTTGGAA CGATTAGAAAAGGAGAACAAAGAATTGAGAAAATTAGTATTGCAGAAAGATGACAAAGGCATTCATCATAGAAAGCTTAAGAAATCTTTG ATTGACATGTATTCTGAAGTTCTTGATGTTCTCTCTGATTATGATGCCAGTTATAATACGCAAGATCATCTGCCACGGGTTGTTGTGGTT GGAGATCAGAGTGCTGGAAAGACTAGTGTGTTGGAAATGATTGCCCAAGCTCGAATATTCCCAAGAGGATCTGGGGAGATGATGACACGT TCTCCAGTTAAGGTGACTCTGAGTGAAGGTCCTCACCATGTGGCCCTATTTAAAGATAGTTCTCGGGAGTTTGATCTTACCAAAGAAGAA GATCTTGCAGCATTAAGACATGAAATAGAACTTCGAATGAGGAAAAATGTGAAAGAAGGCTGTACCGTTAGCCCTGAGACCATATCCTTA AATGTAAAAGGCCCTGGACTACAGAGGATGGTGCTTGTTGACTTACCAGGTGTGATTAATACTGTGACATCAGGCATGGCTCCTGACACA AAGGAAACTATTTTCAGTATCAGCAAAGCTTACATGCAGAATCCTAATGCCATCATACTGTGTATTCAAGATGGATCTGTGGATGCTGAA CGCAGTATTGTTACAGACTTGGTCAGTCAAATGGACCCTCATGGAAGGAGAACCATATTCGTTTTGACCAAAGTAGACCTGGCAGAGAAA AATGTAGCCAGTCCAAGCAGGGCTCAAGTTGGCTTACCAGAAGTTACACTGGGACTTCTCCCTGGTGCAAGAGGAACCCAGCTTCTCCCC AGACTCACTGGAGTTCCTGCTGCACTTGACTTAATTACCTCAGGAAGACGTATTTTAGCAGATGAAGCACTCAAGCTGGGCATTCTAGAT AAAGTTGTAAACTCAGACCCGGTTGAAGAAGCAATCAGATTTGCTCAGAGAGTTTCAGATCAACCTCTAGAATCCCGTAGACTCTGCAAC AAGCCAATTCAGAGCTTGCCCAACATGGACAGCATTTTTAGTGAGGCCCTCTTGAAGATGCGGAGGCAGCACCCTGGGTGTCTTGCACAG GAGGCTTGTGTCCGTGCAGTCCAGGCTGCTGTGCAGTATCCCTATGAAGTGGGCATCAAGAAGGAGGAGGAGCTGTTTCTATATCTTTTG CAATCAGGGCAGGCTAGAGCCCTGCAATATGCTTTCTTCGCTGAAAGGAAAGCAAATAAGTGGTCAACTCCCTCCGGAGCATCGTGGAAA ACAGCATCAGCGCGGCCTGTCTCCTCAGTTGGTGTTGTTGGCTTGGGAACAATGGGCCGAGGCATTGTCATTTCTTTTGCAAGGGCCAGG ATTCCTGTGATTGCTGTAGACTCGGACAAAAACCAGCTAGCAACTGCAAACAAGATGATAACCTCTGTCTTGGAAAAAGAAGCCTCCAAA ATGCAACAGAGCGGCCACCCTTGGTCAGGACCAAAACCCAGGTTAACTTCATCTGTGAAGGAGCTTGGTGGTGTAGATTTAGTCATTGAA GCAGTATTTGAGGAAATGAGCCTGAAGAAGCAGGTCTTTGCTGAACTCTCAGCTGTGTGCAAACCAGAAGCATTTTTGTGCACTAATACT TCAGCCCTGGATGTTGATGAGATTGCTTCTTCCACTGATCGTCCTCACTTGGTCATTGGCACCCACTTCTTTTCGCCAGCTCATGTCATG AAGTTGTTAGAGGTTATTCCCAGCCAATACTCTTCCCCCACTACCATTGCCACTGTTATGAACTTATCAAAAAAGATTAAAAAGATTGGA GTCGTTGTAGGCAACTGTTTTGGATTTGTGGGGAATCGAATGTTGAATCCTTACTACAATCAGGCATATTTCTTGTTAGAAGAAGGCAGC AAACCAGAGGAGGTAGATCAGGTGCTGGAAGAGTTTGGTTTTAAAATGGGACCTTTTAGAGTGTCTGATCTTGCTGGGTTGGATGTGGGC TGGAAATCTAGAAAGGGGCAAGGTCTTACTGGACCTACATTGCTTCCAGGAACTCCTGCCCGAAAAAGGGGTAATAGGAGGTACTGCCCA ATTCCTGATGTGCTCTGTGAATTAGGACGATTTGGCCAGAAGACAGGTAAGGGTTGGTATCAATATGACAAGCCATTGGGTAGGATTCAC AAACCTGATCCCTGGCTTTCCAAATTCCTATCACGGTATAGAAAAACCCATCACATTGAACCACGTACCATTAGCCAGGATGAGATCCTT GAACGCTGCTTATATTCACTTATCAATGAAGCATTCCGTATCTTGGGAGAAGGGATAGCTGCTAGCCCAGAGCACATTGATGTTGTCTAT TTACATGGATATGGATGGCCAAGGCACAAGGGCGGGCCCATGTTCTATGCTTCCACAGTTGGGTTGCCCACAGTTCTAGAGAAATTGCAG AAATATTACAGGCAGAACCCTGATATTCCCCAACTGGAGCCAAGTGACTATCTAAAAAAACTGGCTTCTCAGGGAAACCCTCCCCTGAAA GAATGGCAAAGCTTGGCAGGCTCCCCTAGCAGTAAATTGTGATTCAGTCTTCCAGATTATGCCTCACATGCTAGCATCAGGTAATGCTGA CTGAATTTCAGTGAAATTAAATCAAAAATCCAAAGTAAGATTGTTCTGAAATACAAAGCAAAATAAATAATCATTAGAATCTTCTGTGTA ACGACTCTAATGGTCAAATCTTTAGGAATGTGCTTCCTATGCCTCTGAATCTGTCCTTATCAGATAAATTCAATGCATGAACTTGTGTGA ATATAATACCATAATAGCTAATGAAAGAGGCTCAGGCATAAGTTGAGATTCTCAAATGCTTTTATCATTGGATAAATGTGTCATCAATTA ATAAATGATAAATGCAGCTAAGTCATACATTCATTTTGACTCCTTTCAATGTCACACACATAGTATTGATCAGAAATCTTATGAATCATA CATACACTCAACAAACATTAAAGTTGTAGGAAAAAGACAGTTGGAAATTGGTAAGGGAACTGAGTACTTCAAACCAGCACAGGGAACTTA GGTTAGTGTGGCAAGCCTTTCCTCTTCTGGTCTTTCCTCTTCTGTTTATGGAGAAATAATAGAAAGTAGTAAGTCGTTAACTTAGTGTAA GAAGGGTCTTAGAGAACATCTAACCTTCTAGGATTTCCCAATTCTGTGATAGAGTAATGACACCAGTTTTCCTGTCATGACAAGCCTCTG TGATGTTACATATGGAAATGGTTGAATCTTGAAAAATCTAAAATTGTTGCAAAACATATTTTGTATGATTTTGTTGTAAGAGTTCTTCTC TTTTTACTTTTTGCCTTGTGTAGTTAAAAATTAAGGGGCTGGTCAATACAAAAACTTGTACACAAATATTTATAGCAGAATTATTCATAA TGGCCAAAAGCTGAATACAACCCAAATGTCTATGAACTAATGAATAGATAAACCAAATCTGGTATATCCATACAATGGACTATATTATTC AGCCATAAAAAGAAATAAAGGGCCAGGCACAGTGGCTCACACCTGTAATCCCAGCACTTTGGGAGGCTGAGGCAGGAGGATTGTTTGAGG CCAGAAATTTGAGACCAGCCTGGGCAACATAGCAAAACCCTGTCTCTACAAAAAATACTTTCCGTACATTAGTGGTTGCCTAAGGCTAGA ATTGGGGGTGATGAATGGGGAGTACAGGATTCATCTAATGGGTACAGGATTTCTTTATGGTTCATGAAAATGGTCTAAACTTATTGTGGT AATGGTCACATAACAATATATTAAAAACCATTGAGTTGTATATTTTAAGTGGGTGAATTATATGGTATGTGAATTATATCTCAATAAAGT TGTTAGTAAATAAATGGGGCTGAAGATGTTATCCTTCATTGTGGTGTAAATGAACTTTCACAATATTTTCACCTGTGAACCCAAATAAAA TGATTAAAGTTCTGATGGAAAAATCTTGAATGGAGTATAAGTTTTCCGTTGTTAAAAAGCAAACAAAAAACCAACAAAAAATCCAAGTGT GCCTTGAATTGTACAGAGCACAATTATTATGTTTGAAATGTGTACTACTTAATTTTATATAATTTGGTTTGTGAAATTAAAGACATCAAT >61523_61523_7_OPA1-EHHADH_OPA1_chr3_193361894_ENST00000361828_EHHADH_chr3_184947331_ENST00000231887_length(amino acids)=1168AA_BP=562 MSTGACQALAEVHAPLGGPRPRLCALAAEGHFLGHSWTGSRAGAHTGAPAWPSRRLRDLPAGGMWRLRRAAVACEVCQSLVKHSSGIKGS LPLQKLHLVSRSIYHSHHPTLKLQRPQLRTSFQQFSSLTNLPLRKLKFSPIKYGYQPRRNFWPARLATRLLKLRYLILGSAVGGGYTAKK TFDQWKDMIPDLSEYKWIVPDIVWEIDEYIDFEKIRKALPSSEDLVKLAPDFDKIVESLSLLKDFFTSGHKLVSEVIGASDLLLLLGSPE ETAFRATDRGSESDKHFRKVSDKEKIDQLQEELLHTQLKYQRILERLEKENKELRKLVLQKDDKGIHHRKLKKSLIDMYSEVLDVLSDYD ASYNTQDHLPRVVVVGDQSAGKTSVLEMIAQARIFPRGSGEMMTRSPVKVTLSEGPHHVALFKDSSREFDLTKEEDLAALRHEIELRMRK NVKEGCTVSPETISLNVKGPGLQRMVLVDLPGVINTVTSGMAPDTKETIFSISKAYMQNPNAIILCIQDGSVDAERSIVTDLVSQMDPHG RRTIFVLTKVDLAEKNVASPSRAQVGLPEVTLGLLPGARGTQLLPRLTGVPAALDLITSGRRILADEALKLGILDKVVNSDPVEEAIRFA QRVSDQPLESRRLCNKPIQSLPNMDSIFSEALLKMRRQHPGCLAQEACVRAVQAAVQYPYEVGIKKEEELFLYLLQSGQARALQYAFFAE RKANKWSTPSGASWKTASARPVSSVGVVGLGTMGRGIVISFARARIPVIAVDSDKNQLATANKMITSVLEKEASKMQQSGHPWSGPKPRL TSSVKELGGVDLVIEAVFEEMSLKKQVFAELSAVCKPEAFLCTNTSALDVDEIASSTDRPHLVIGTHFFSPAHVMKLLEVIPSQYSSPTT IATVMNLSKKIKKIGVVVGNCFGFVGNRMLNPYYNQAYFLLEEGSKPEEVDQVLEEFGFKMGPFRVSDLAGLDVGWKSRKGQGLTGPTLL PGTPARKRGNRRYCPIPDVLCELGRFGQKTGKGWYQYDKPLGRIHKPDPWLSKFLSRYRKTHHIEPRTISQDEILERCLYSLINEAFRIL -------------------------------------------------------------- >61523_61523_8_OPA1-EHHADH_OPA1_chr3_193361894_ENST00000361828_EHHADH_chr3_184947331_ENST00000456310_length(transcript)=3808nt_BP=1731nt GTGCTGCCCGCCTAGAAAGGGTGAAGTGGTTGTTTCCGTGACGGACTGAGTACGGGTGCCTGTCAGGCTCTTGCGGAAGTCCATGCGCCA TTGGGAGGGCCTCGGCCGCGGCTCTGTGCCCTTGCTGCTGAGGGCCACTTCCTGGGTCATTCCTGGACCGGGAGCCGGGCTGGGGCTCAC ACGGGGGCTCCCGCGTGGCCGTCTCGGCGCCTGCGTGACCTCCCCGCCGGCGGGATGTGGCGACTACGTCGGGCCGCTGTGGCCTGTGAG GTCTGCCAGTCTTTAGTGAAACACAGCTCTGGAATAAAAGGAAGTTTACCACTACAAAAACTACATCTGGTTTCACGAAGCATTTATCAT TCACATCATCCTACCTTAAAGCTTCAACGACCCCAATTAAGGACATCCTTTCAGCAGTTCTCTTCTCTGACAAACCTTCCTTTACGTAAA CTGAAATTCTCTCCAATTAAATATGGCTACCAGCCTCGCAGGAATTTTTGGCCAGCAAGATTAGCTACGAGACTCTTAAAACTTCGCTAT CTCATACTAGGATCGGCTGTTGGGGGTGGCTACACAGCCAAAAAGACTTTTGATCAGTGGAAAGATATGATACCGGACCTTAGTGAATAT AAATGGATTGTGCCTGACATTGTGTGGGAAATTGATGAGTATATCGATTTTGAGAAAATTAGAAAAGCCCTTCCTAGTTCAGAAGACCTT GTAAAGTTAGCACCAGACTTTGACAAGATTGTTGAAAGCCTTAGCTTATTGAAGGACTTTTTTACCTCAGGTCACAAATTGGTTAGTGAA GTCATAGGAGCTTCTGACCTACTTCTCTTGTTAGGTTCTCCGGAAGAAACGGCGTTTAGAGCAACAGATCGTGGATCTGAAAGTGACAAG CATTTTAGAAAGGTGTCAGACAAAGAGAAAATTGACCAACTTCAGGAAGAACTTCTGCACACTCAGTTGAAGTATCAGAGAATCTTGGAA CGATTAGAAAAGGAGAACAAAGAATTGAGAAAATTAGTATTGCAGAAAGATGACAAAGGCATTCATCATAGAAAGCTTAAGAAATCTTTG ATTGACATGTATTCTGAAGTTCTTGATGTTCTCTCTGATTATGATGCCAGTTATAATACGCAAGATCATCTGCCACGGGTTGTTGTGGTT GGAGATCAGAGTGCTGGAAAGACTAGTGTGTTGGAAATGATTGCCCAAGCTCGAATATTCCCAAGAGGATCTGGGGAGATGATGACACGT TCTCCAGTTAAGGTGACTCTGAGTGAAGGTCCTCACCATGTGGCCCTATTTAAAGATAGTTCTCGGGAGTTTGATCTTACCAAAGAAGAA GATCTTGCAGCATTAAGACATGAAATAGAACTTCGAATGAGGAAAAATGTGAAAGAAGGCTGTACCGTTAGCCCTGAGACCATATCCTTA AATGTAAAAGGCCCTGGACTACAGAGGATGGTGCTTGTTGACTTACCAGGTGTGATTAATACTGTGACATCAGGCATGGCTCCTGACACA AAGGAAACTATTTTCAGTATCAGCAAAGCTTACATGCAGAATCCTAATGCCATCATACTGTGTATTCAAGATGGATCTGTGGATGCTGAA CGCAGTATTGTTACAGACTTGGTCAGTCAAATGGACCCTCATGGAAGGAGAACCATATTCGTTTTGACCAAAGTAGACCTGGCAGAGAAA AATGTAGCCAGTCCAAGCAGGGCTCAAGTTGGCTTACCAGAAGTTACACTGGGACTTCTCCCTGGTGCAAGAGGAACCCAGCTTCTCCCC AGACTCACTGGAGTTCCTGCTGCACTTGACTTAATTACCTCAGGAAGACGTATTTTAGCAGATGAAGCACTCAAGCTGGGCATTCTAGAT AAAGTTGTAAACTCAGACCCGGTTGAAGAAGCAATCAGATTTGCTCAGAGAGTTTCAGATCAACCTCTAGAATCCCGTAGACTCTGCAAC AAGCCAATTCAGAGCTTGCCCAACATGGACAGCATTTTTAGTGAGGCCCTCTTGAAGATGCGGAGGCAGCACCCTGGGTGTCTTGCACAG GAGGCTTGTGTCCGTGCAGTCCAGGCTGCTGTGCAGTATCCCTATGAAGTGGGCATCAAGAAGGAGGAGGAGCTGTTTCTATATCTTTTG CAATCAGGGCAGGCTAGAGCCCTGCAATATGCTTTCTTCGCTGAAAGGAAAGCAAATAAGTGGTCAACTCCCTCCGGAGCATCGTGGAAA ACAGCATCAGCGCGGCCTGTCTCCTCAGTTGGTGTTGTTGGCTTGGGAACAATGGGCCGAGGCATTGTCATTTCTTTTGCAAGGGCCAGG ATTCCTGTGATTGCTGTAGACTCGGACAAAAACCAGCTAGCAACTGCAAACAAGATGATAACCTCTGTCTTGGAAAAAGAAGCCTCCAAA ATGCAACAGAGCGGCCACCCTTGGTCAGGACCAAAACCCAGGTTAACTTCATCTGTGAAGGAGCTTGGTGGTGTAGATTTAGTCATTGAA GCAGTATTTGAGGAAATGAGCCTGAAGAAGCAGGTCTTTGCTGAACTCTCAGCTGTGTGCAAACCAGAAGCATTTTTGTGCACTAATACT TCAGCCCTGGATGTTGATGAGATTGCTTCTTCCACTGATCGTCCTCACTTGGTCATTGGCACCCACTTCTTTTCGCCAGCTCATGTCATG AAGTTGTTAGAGGTTATTCCCAGCCAATACTCTTCCCCCACTACCATTGCCACTGTTATGAACTTATCAAAAAAGATTAAAAAGATTGGA GTCGTTGTAGGCAACTGTTTTGGATTTGTGGGGAATCGAATGTTGAATCCTTACTACAATCAGGCATATTTCTTGTTAGAAGAAGGCAGC AAACCAGAGGAGGTAGATCAGGTGCTGGAAGAGTTTGGTTTTAAAATGGGACCTTTTAGAGTGTCTGATCTTGCTGGGTTGGATGTGGGC TGGAAATCTAGAAAGGGGCAAGGTCTTACTGGACCTACATTGCTTCCAGGAACTCCTGCCCGAAAAAGGGGTAATAGGAGGTACTGCCCA ATTCCTGATGTGCTCTGTGAATTAGGACGATTTGGCCAGAAGACAGGTAAGGGTTGGTATCAATATGACAAGCCATTGGGTAGGATTCAC AAACCTGATCCCTGGCTTTCCAAATTCCTATCACGGTATAGAAAAACCCATCACATTGAACCACGTACCATTAGCCAGGATGAGATCCTT GAACGCTGCTTATATTCACTTATCAATGAAGCATTCCGTATCTTGGGAGAAGGGATAGCTGCTAGCCCAGAGCACATTGATGTTGTCTAT TTACATGGATATGGATGGCCAAGGCACAAGGGCGGGCCCATGTTCTATGCTTCCACAGTTGGGTTGCCCACAGTTCTAGAGAAATTGCAG AAATATTACAGGCAGAACCCTGATATTCCCCAACTGGAGCCAAGTGACTATCTAAAAAAACTGGCTTCTCAGGGAAACCCTCCCCTGAAA GAATGGCAAAGCTTGGCAGGCTCCCCTAGCAGTAAATTGTGATTCAGTCTTCCAGATTATGCCTCACATGCTAGCATCAGGTAATGCTGA CTGAATTTCAGTGAAATTAAATCAAAAATCCAAAGTAAGATTGTTCTGAAATACAAAGCAAAATAAATAATCATTAGAATCTTCTGTGTA ACGACTCTAATGGTCAAATCTTTAGGAATGTGCTTCCTATGCCTCTGAATCTGTCCTTATCAGATAAATTCAATGCATGAACTTGTGTGA >61523_61523_8_OPA1-EHHADH_OPA1_chr3_193361894_ENST00000361828_EHHADH_chr3_184947331_ENST00000456310_length(amino acids)=1168AA_BP=562 MSTGACQALAEVHAPLGGPRPRLCALAAEGHFLGHSWTGSRAGAHTGAPAWPSRRLRDLPAGGMWRLRRAAVACEVCQSLVKHSSGIKGS LPLQKLHLVSRSIYHSHHPTLKLQRPQLRTSFQQFSSLTNLPLRKLKFSPIKYGYQPRRNFWPARLATRLLKLRYLILGSAVGGGYTAKK TFDQWKDMIPDLSEYKWIVPDIVWEIDEYIDFEKIRKALPSSEDLVKLAPDFDKIVESLSLLKDFFTSGHKLVSEVIGASDLLLLLGSPE ETAFRATDRGSESDKHFRKVSDKEKIDQLQEELLHTQLKYQRILERLEKENKELRKLVLQKDDKGIHHRKLKKSLIDMYSEVLDVLSDYD ASYNTQDHLPRVVVVGDQSAGKTSVLEMIAQARIFPRGSGEMMTRSPVKVTLSEGPHHVALFKDSSREFDLTKEEDLAALRHEIELRMRK NVKEGCTVSPETISLNVKGPGLQRMVLVDLPGVINTVTSGMAPDTKETIFSISKAYMQNPNAIILCIQDGSVDAERSIVTDLVSQMDPHG RRTIFVLTKVDLAEKNVASPSRAQVGLPEVTLGLLPGARGTQLLPRLTGVPAALDLITSGRRILADEALKLGILDKVVNSDPVEEAIRFA QRVSDQPLESRRLCNKPIQSLPNMDSIFSEALLKMRRQHPGCLAQEACVRAVQAAVQYPYEVGIKKEEELFLYLLQSGQARALQYAFFAE RKANKWSTPSGASWKTASARPVSSVGVVGLGTMGRGIVISFARARIPVIAVDSDKNQLATANKMITSVLEKEASKMQQSGHPWSGPKPRL TSSVKELGGVDLVIEAVFEEMSLKKQVFAELSAVCKPEAFLCTNTSALDVDEIASSTDRPHLVIGTHFFSPAHVMKLLEVIPSQYSSPTT IATVMNLSKKIKKIGVVVGNCFGFVGNRMLNPYYNQAYFLLEEGSKPEEVDQVLEEFGFKMGPFRVSDLAGLDVGWKSRKGQGLTGPTLL PGTPARKRGNRRYCPIPDVLCELGRFGQKTGKGWYQYDKPLGRIHKPDPWLSKFLSRYRKTHHIEPRTISQDEILERCLYSLINEAFRIL -------------------------------------------------------------- >61523_61523_9_OPA1-EHHADH_OPA1_chr3_193361894_ENST00000361908_EHHADH_chr3_184947331_ENST00000231887_length(transcript)=5211nt_BP=1788nt GTGCTGCCCGCCTAGAAAGGGTGAAGTGGTTGTTTCCGTGACGGACTGAGTACGGGTGCCTGTCAGGCTCTTGCGGAAGTCCATGCGCCA TTGGGAGGGCCTCGGCCGCGGCTCTGTGCCCTTGCTGCTGAGGGCCACTTCCTGGGTCATTCCTGGACCGGGAGCCGGGCTGGGGCTCAC ACGGGGGCTCCCGCGTGGCCGTCTCGGCGCCTGCGTGACCTCCCCGCCGGCGGGATGTGGCGACTACGTCGGGCCGCTGTGGCCTGTGAG GTCTGCCAGTCTTTAGTGAAACACAGCTCTGGAATAAAAGGAAGTTTACCACTACAAAAACTACATCTGGTTTCACGAAGCATTTATCAT TCACATCATCCTACCTTAAAGCTTCAACGACCCCAATTAAGGACATCCTTTCAGCAGTTCTCTTCTCTGACAAACCTTCCTTTACGTAAA CTGAAATTCTCTCCAATTAAATATGGCTACCAGCCTCGCAGGAATTTTTGGCCAGCAAGATTAGCTACGAGACTCTTAAAACTTCGCTAT CTCATACTAGGATCGGCTGTTGGGGGTGGCTACACAGCCAAAAAGACTTTTGATCAGTGGAAAGATATGATACCGGACCTTAGTGAATAT AAATGGATTGTGCCTGACATTGTGTGGGAAATTGATGAGTATATCGATTTTGAGAAAATTAGAAAAGCCCTTCCTAGTTCAGAAGACCTT GTAAAGTTAGCACCAGACTTTGACAAGATTGTTGAAAGCCTTAGCTTATTGAAGGACTTTTTTACCTCAGGTTCTCCGGAAGAAACGGCG TTTAGAGCAACAGATCGTGGATCTGAAAGTGACAAGCATTTTAGAAAGGGTCTGCTTGGTGAGCTCATTCTCTTACAACAACAAATTCAA GAGCATGAAGAGGAAGCGCGCAGAGCCGCTGGCCAATATAGCACGAGCTATGCCCAACAGAAGCGCAAGGTGTCAGACAAAGAGAAAATT GACCAACTTCAGGAAGAACTTCTGCACACTCAGTTGAAGTATCAGAGAATCTTGGAACGATTAGAAAAGGAGAACAAAGAATTGAGAAAA TTAGTATTGCAGAAAGATGACAAAGGCATTCATCATAGAAAGCTTAAGAAATCTTTGATTGACATGTATTCTGAAGTTCTTGATGTTCTC TCTGATTATGATGCCAGTTATAATACGCAAGATCATCTGCCACGGGTTGTTGTGGTTGGAGATCAGAGTGCTGGAAAGACTAGTGTGTTG GAAATGATTGCCCAAGCTCGAATATTCCCAAGAGGATCTGGGGAGATGATGACACGTTCTCCAGTTAAGGTGACTCTGAGTGAAGGTCCT CACCATGTGGCCCTATTTAAAGATAGTTCTCGGGAGTTTGATCTTACCAAAGAAGAAGATCTTGCAGCATTAAGACATGAAATAGAACTT CGAATGAGGAAAAATGTGAAAGAAGGCTGTACCGTTAGCCCTGAGACCATATCCTTAAATGTAAAAGGCCCTGGACTACAGAGGATGGTG CTTGTTGACTTACCAGGTGTGATTAATACTGTGACATCAGGCATGGCTCCTGACACAAAGGAAACTATTTTCAGTATCAGCAAAGCTTAC ATGCAGAATCCTAATGCCATCATACTGTGTATTCAAGATGGATCTGTGGATGCTGAACGCAGTATTGTTACAGACTTGGTCAGTCAAATG GACCCTCATGGAAGGAGAACCATATTCGTTTTGACCAAAGTAGACCTGGCAGAGAAAAATGTAGCCAGTCCAAGCAGGGCTCAAGTTGGC TTACCAGAAGTTACACTGGGACTTCTCCCTGGTGCAAGAGGAACCCAGCTTCTCCCCAGACTCACTGGAGTTCCTGCTGCACTTGACTTA ATTACCTCAGGAAGACGTATTTTAGCAGATGAAGCACTCAAGCTGGGCATTCTAGATAAAGTTGTAAACTCAGACCCGGTTGAAGAAGCA ATCAGATTTGCTCAGAGAGTTTCAGATCAACCTCTAGAATCCCGTAGACTCTGCAACAAGCCAATTCAGAGCTTGCCCAACATGGACAGC ATTTTTAGTGAGGCCCTCTTGAAGATGCGGAGGCAGCACCCTGGGTGTCTTGCACAGGAGGCTTGTGTCCGTGCAGTCCAGGCTGCTGTG CAGTATCCCTATGAAGTGGGCATCAAGAAGGAGGAGGAGCTGTTTCTATATCTTTTGCAATCAGGGCAGGCTAGAGCCCTGCAATATGCT TTCTTCGCTGAAAGGAAAGCAAATAAGTGGTCAACTCCCTCCGGAGCATCGTGGAAAACAGCATCAGCGCGGCCTGTCTCCTCAGTTGGT GTTGTTGGCTTGGGAACAATGGGCCGAGGCATTGTCATTTCTTTTGCAAGGGCCAGGATTCCTGTGATTGCTGTAGACTCGGACAAAAAC CAGCTAGCAACTGCAAACAAGATGATAACCTCTGTCTTGGAAAAAGAAGCCTCCAAAATGCAACAGAGCGGCCACCCTTGGTCAGGACCA AAACCCAGGTTAACTTCATCTGTGAAGGAGCTTGGTGGTGTAGATTTAGTCATTGAAGCAGTATTTGAGGAAATGAGCCTGAAGAAGCAG GTCTTTGCTGAACTCTCAGCTGTGTGCAAACCAGAAGCATTTTTGTGCACTAATACTTCAGCCCTGGATGTTGATGAGATTGCTTCTTCC ACTGATCGTCCTCACTTGGTCATTGGCACCCACTTCTTTTCGCCAGCTCATGTCATGAAGTTGTTAGAGGTTATTCCCAGCCAATACTCT TCCCCCACTACCATTGCCACTGTTATGAACTTATCAAAAAAGATTAAAAAGATTGGAGTCGTTGTAGGCAACTGTTTTGGATTTGTGGGG AATCGAATGTTGAATCCTTACTACAATCAGGCATATTTCTTGTTAGAAGAAGGCAGCAAACCAGAGGAGGTAGATCAGGTGCTGGAAGAG TTTGGTTTTAAAATGGGACCTTTTAGAGTGTCTGATCTTGCTGGGTTGGATGTGGGCTGGAAATCTAGAAAGGGGCAAGGTCTTACTGGA CCTACATTGCTTCCAGGAACTCCTGCCCGAAAAAGGGGTAATAGGAGGTACTGCCCAATTCCTGATGTGCTCTGTGAATTAGGACGATTT GGCCAGAAGACAGGTAAGGGTTGGTATCAATATGACAAGCCATTGGGTAGGATTCACAAACCTGATCCCTGGCTTTCCAAATTCCTATCA CGGTATAGAAAAACCCATCACATTGAACCACGTACCATTAGCCAGGATGAGATCCTTGAACGCTGCTTATATTCACTTATCAATGAAGCA TTCCGTATCTTGGGAGAAGGGATAGCTGCTAGCCCAGAGCACATTGATGTTGTCTATTTACATGGATATGGATGGCCAAGGCACAAGGGC GGGCCCATGTTCTATGCTTCCACAGTTGGGTTGCCCACAGTTCTAGAGAAATTGCAGAAATATTACAGGCAGAACCCTGATATTCCCCAA CTGGAGCCAAGTGACTATCTAAAAAAACTGGCTTCTCAGGGAAACCCTCCCCTGAAAGAATGGCAAAGCTTGGCAGGCTCCCCTAGCAGT AAATTGTGATTCAGTCTTCCAGATTATGCCTCACATGCTAGCATCAGGTAATGCTGACTGAATTTCAGTGAAATTAAATCAAAAATCCAA AGTAAGATTGTTCTGAAATACAAAGCAAAATAAATAATCATTAGAATCTTCTGTGTAACGACTCTAATGGTCAAATCTTTAGGAATGTGC TTCCTATGCCTCTGAATCTGTCCTTATCAGATAAATTCAATGCATGAACTTGTGTGAATATAATACCATAATAGCTAATGAAAGAGGCTC AGGCATAAGTTGAGATTCTCAAATGCTTTTATCATTGGATAAATGTGTCATCAATTAATAAATGATAAATGCAGCTAAGTCATACATTCA TTTTGACTCCTTTCAATGTCACACACATAGTATTGATCAGAAATCTTATGAATCATACATACACTCAACAAACATTAAAGTTGTAGGAAA AAGACAGTTGGAAATTGGTAAGGGAACTGAGTACTTCAAACCAGCACAGGGAACTTAGGTTAGTGTGGCAAGCCTTTCCTCTTCTGGTCT TTCCTCTTCTGTTTATGGAGAAATAATAGAAAGTAGTAAGTCGTTAACTTAGTGTAAGAAGGGTCTTAGAGAACATCTAACCTTCTAGGA TTTCCCAATTCTGTGATAGAGTAATGACACCAGTTTTCCTGTCATGACAAGCCTCTGTGATGTTACATATGGAAATGGTTGAATCTTGAA AAATCTAAAATTGTTGCAAAACATATTTTGTATGATTTTGTTGTAAGAGTTCTTCTCTTTTTACTTTTTGCCTTGTGTAGTTAAAAATTA AGGGGCTGGTCAATACAAAAACTTGTACACAAATATTTATAGCAGAATTATTCATAATGGCCAAAAGCTGAATACAACCCAAATGTCTAT GAACTAATGAATAGATAAACCAAATCTGGTATATCCATACAATGGACTATATTATTCAGCCATAAAAAGAAATAAAGGGCCAGGCACAGT GGCTCACACCTGTAATCCCAGCACTTTGGGAGGCTGAGGCAGGAGGATTGTTTGAGGCCAGAAATTTGAGACCAGCCTGGGCAACATAGC AAAACCCTGTCTCTACAAAAAATACTTTCCGTACATTAGTGGTTGCCTAAGGCTAGAATTGGGGGTGATGAATGGGGAGTACAGGATTCA TCTAATGGGTACAGGATTTCTTTATGGTTCATGAAAATGGTCTAAACTTATTGTGGTAATGGTCACATAACAATATATTAAAAACCATTG AGTTGTATATTTTAAGTGGGTGAATTATATGGTATGTGAATTATATCTCAATAAAGTTGTTAGTAAATAAATGGGGCTGAAGATGTTATC CTTCATTGTGGTGTAAATGAACTTTCACAATATTTTCACCTGTGAACCCAAATAAAATGATTAAAGTTCTGATGGAAAAATCTTGAATGG AGTATAAGTTTTCCGTTGTTAAAAAGCAAACAAAAAACCAACAAAAAATCCAAGTGTGCCTTGAATTGTACAGAGCACAATTATTATGTT >61523_61523_9_OPA1-EHHADH_OPA1_chr3_193361894_ENST00000361908_EHHADH_chr3_184947331_ENST00000231887_length(amino acids)=1187AA_BP=581 MSTGACQALAEVHAPLGGPRPRLCALAAEGHFLGHSWTGSRAGAHTGAPAWPSRRLRDLPAGGMWRLRRAAVACEVCQSLVKHSSGIKGS LPLQKLHLVSRSIYHSHHPTLKLQRPQLRTSFQQFSSLTNLPLRKLKFSPIKYGYQPRRNFWPARLATRLLKLRYLILGSAVGGGYTAKK TFDQWKDMIPDLSEYKWIVPDIVWEIDEYIDFEKIRKALPSSEDLVKLAPDFDKIVESLSLLKDFFTSGSPEETAFRATDRGSESDKHFR KGLLGELILLQQQIQEHEEEARRAAGQYSTSYAQQKRKVSDKEKIDQLQEELLHTQLKYQRILERLEKENKELRKLVLQKDDKGIHHRKL KKSLIDMYSEVLDVLSDYDASYNTQDHLPRVVVVGDQSAGKTSVLEMIAQARIFPRGSGEMMTRSPVKVTLSEGPHHVALFKDSSREFDL TKEEDLAALRHEIELRMRKNVKEGCTVSPETISLNVKGPGLQRMVLVDLPGVINTVTSGMAPDTKETIFSISKAYMQNPNAIILCIQDGS VDAERSIVTDLVSQMDPHGRRTIFVLTKVDLAEKNVASPSRAQVGLPEVTLGLLPGARGTQLLPRLTGVPAALDLITSGRRILADEALKL GILDKVVNSDPVEEAIRFAQRVSDQPLESRRLCNKPIQSLPNMDSIFSEALLKMRRQHPGCLAQEACVRAVQAAVQYPYEVGIKKEEELF LYLLQSGQARALQYAFFAERKANKWSTPSGASWKTASARPVSSVGVVGLGTMGRGIVISFARARIPVIAVDSDKNQLATANKMITSVLEK EASKMQQSGHPWSGPKPRLTSSVKELGGVDLVIEAVFEEMSLKKQVFAELSAVCKPEAFLCTNTSALDVDEIASSTDRPHLVIGTHFFSP AHVMKLLEVIPSQYSSPTTIATVMNLSKKIKKIGVVVGNCFGFVGNRMLNPYYNQAYFLLEEGSKPEEVDQVLEEFGFKMGPFRVSDLAG LDVGWKSRKGQGLTGPTLLPGTPARKRGNRRYCPIPDVLCELGRFGQKTGKGWYQYDKPLGRIHKPDPWLSKFLSRYRKTHHIEPRTISQ DEILERCLYSLINEAFRILGEGIAASPEHIDVVYLHGYGWPRHKGGPMFYASTVGLPTVLEKLQKYYRQNPDIPQLEPSDYLKKLASQGN -------------------------------------------------------------- >61523_61523_10_OPA1-EHHADH_OPA1_chr3_193361894_ENST00000361908_EHHADH_chr3_184947331_ENST00000456310_length(transcript)=3865nt_BP=1788nt GTGCTGCCCGCCTAGAAAGGGTGAAGTGGTTGTTTCCGTGACGGACTGAGTACGGGTGCCTGTCAGGCTCTTGCGGAAGTCCATGCGCCA TTGGGAGGGCCTCGGCCGCGGCTCTGTGCCCTTGCTGCTGAGGGCCACTTCCTGGGTCATTCCTGGACCGGGAGCCGGGCTGGGGCTCAC ACGGGGGCTCCCGCGTGGCCGTCTCGGCGCCTGCGTGACCTCCCCGCCGGCGGGATGTGGCGACTACGTCGGGCCGCTGTGGCCTGTGAG GTCTGCCAGTCTTTAGTGAAACACAGCTCTGGAATAAAAGGAAGTTTACCACTACAAAAACTACATCTGGTTTCACGAAGCATTTATCAT TCACATCATCCTACCTTAAAGCTTCAACGACCCCAATTAAGGACATCCTTTCAGCAGTTCTCTTCTCTGACAAACCTTCCTTTACGTAAA CTGAAATTCTCTCCAATTAAATATGGCTACCAGCCTCGCAGGAATTTTTGGCCAGCAAGATTAGCTACGAGACTCTTAAAACTTCGCTAT CTCATACTAGGATCGGCTGTTGGGGGTGGCTACACAGCCAAAAAGACTTTTGATCAGTGGAAAGATATGATACCGGACCTTAGTGAATAT AAATGGATTGTGCCTGACATTGTGTGGGAAATTGATGAGTATATCGATTTTGAGAAAATTAGAAAAGCCCTTCCTAGTTCAGAAGACCTT GTAAAGTTAGCACCAGACTTTGACAAGATTGTTGAAAGCCTTAGCTTATTGAAGGACTTTTTTACCTCAGGTTCTCCGGAAGAAACGGCG TTTAGAGCAACAGATCGTGGATCTGAAAGTGACAAGCATTTTAGAAAGGGTCTGCTTGGTGAGCTCATTCTCTTACAACAACAAATTCAA GAGCATGAAGAGGAAGCGCGCAGAGCCGCTGGCCAATATAGCACGAGCTATGCCCAACAGAAGCGCAAGGTGTCAGACAAAGAGAAAATT GACCAACTTCAGGAAGAACTTCTGCACACTCAGTTGAAGTATCAGAGAATCTTGGAACGATTAGAAAAGGAGAACAAAGAATTGAGAAAA TTAGTATTGCAGAAAGATGACAAAGGCATTCATCATAGAAAGCTTAAGAAATCTTTGATTGACATGTATTCTGAAGTTCTTGATGTTCTC TCTGATTATGATGCCAGTTATAATACGCAAGATCATCTGCCACGGGTTGTTGTGGTTGGAGATCAGAGTGCTGGAAAGACTAGTGTGTTG GAAATGATTGCCCAAGCTCGAATATTCCCAAGAGGATCTGGGGAGATGATGACACGTTCTCCAGTTAAGGTGACTCTGAGTGAAGGTCCT CACCATGTGGCCCTATTTAAAGATAGTTCTCGGGAGTTTGATCTTACCAAAGAAGAAGATCTTGCAGCATTAAGACATGAAATAGAACTT CGAATGAGGAAAAATGTGAAAGAAGGCTGTACCGTTAGCCCTGAGACCATATCCTTAAATGTAAAAGGCCCTGGACTACAGAGGATGGTG CTTGTTGACTTACCAGGTGTGATTAATACTGTGACATCAGGCATGGCTCCTGACACAAAGGAAACTATTTTCAGTATCAGCAAAGCTTAC ATGCAGAATCCTAATGCCATCATACTGTGTATTCAAGATGGATCTGTGGATGCTGAACGCAGTATTGTTACAGACTTGGTCAGTCAAATG GACCCTCATGGAAGGAGAACCATATTCGTTTTGACCAAAGTAGACCTGGCAGAGAAAAATGTAGCCAGTCCAAGCAGGGCTCAAGTTGGC TTACCAGAAGTTACACTGGGACTTCTCCCTGGTGCAAGAGGAACCCAGCTTCTCCCCAGACTCACTGGAGTTCCTGCTGCACTTGACTTA ATTACCTCAGGAAGACGTATTTTAGCAGATGAAGCACTCAAGCTGGGCATTCTAGATAAAGTTGTAAACTCAGACCCGGTTGAAGAAGCA ATCAGATTTGCTCAGAGAGTTTCAGATCAACCTCTAGAATCCCGTAGACTCTGCAACAAGCCAATTCAGAGCTTGCCCAACATGGACAGC ATTTTTAGTGAGGCCCTCTTGAAGATGCGGAGGCAGCACCCTGGGTGTCTTGCACAGGAGGCTTGTGTCCGTGCAGTCCAGGCTGCTGTG CAGTATCCCTATGAAGTGGGCATCAAGAAGGAGGAGGAGCTGTTTCTATATCTTTTGCAATCAGGGCAGGCTAGAGCCCTGCAATATGCT TTCTTCGCTGAAAGGAAAGCAAATAAGTGGTCAACTCCCTCCGGAGCATCGTGGAAAACAGCATCAGCGCGGCCTGTCTCCTCAGTTGGT GTTGTTGGCTTGGGAACAATGGGCCGAGGCATTGTCATTTCTTTTGCAAGGGCCAGGATTCCTGTGATTGCTGTAGACTCGGACAAAAAC CAGCTAGCAACTGCAAACAAGATGATAACCTCTGTCTTGGAAAAAGAAGCCTCCAAAATGCAACAGAGCGGCCACCCTTGGTCAGGACCA AAACCCAGGTTAACTTCATCTGTGAAGGAGCTTGGTGGTGTAGATTTAGTCATTGAAGCAGTATTTGAGGAAATGAGCCTGAAGAAGCAG GTCTTTGCTGAACTCTCAGCTGTGTGCAAACCAGAAGCATTTTTGTGCACTAATACTTCAGCCCTGGATGTTGATGAGATTGCTTCTTCC ACTGATCGTCCTCACTTGGTCATTGGCACCCACTTCTTTTCGCCAGCTCATGTCATGAAGTTGTTAGAGGTTATTCCCAGCCAATACTCT TCCCCCACTACCATTGCCACTGTTATGAACTTATCAAAAAAGATTAAAAAGATTGGAGTCGTTGTAGGCAACTGTTTTGGATTTGTGGGG AATCGAATGTTGAATCCTTACTACAATCAGGCATATTTCTTGTTAGAAGAAGGCAGCAAACCAGAGGAGGTAGATCAGGTGCTGGAAGAG TTTGGTTTTAAAATGGGACCTTTTAGAGTGTCTGATCTTGCTGGGTTGGATGTGGGCTGGAAATCTAGAAAGGGGCAAGGTCTTACTGGA CCTACATTGCTTCCAGGAACTCCTGCCCGAAAAAGGGGTAATAGGAGGTACTGCCCAATTCCTGATGTGCTCTGTGAATTAGGACGATTT GGCCAGAAGACAGGTAAGGGTTGGTATCAATATGACAAGCCATTGGGTAGGATTCACAAACCTGATCCCTGGCTTTCCAAATTCCTATCA CGGTATAGAAAAACCCATCACATTGAACCACGTACCATTAGCCAGGATGAGATCCTTGAACGCTGCTTATATTCACTTATCAATGAAGCA TTCCGTATCTTGGGAGAAGGGATAGCTGCTAGCCCAGAGCACATTGATGTTGTCTATTTACATGGATATGGATGGCCAAGGCACAAGGGC GGGCCCATGTTCTATGCTTCCACAGTTGGGTTGCCCACAGTTCTAGAGAAATTGCAGAAATATTACAGGCAGAACCCTGATATTCCCCAA CTGGAGCCAAGTGACTATCTAAAAAAACTGGCTTCTCAGGGAAACCCTCCCCTGAAAGAATGGCAAAGCTTGGCAGGCTCCCCTAGCAGT AAATTGTGATTCAGTCTTCCAGATTATGCCTCACATGCTAGCATCAGGTAATGCTGACTGAATTTCAGTGAAATTAAATCAAAAATCCAA AGTAAGATTGTTCTGAAATACAAAGCAAAATAAATAATCATTAGAATCTTCTGTGTAACGACTCTAATGGTCAAATCTTTAGGAATGTGC >61523_61523_10_OPA1-EHHADH_OPA1_chr3_193361894_ENST00000361908_EHHADH_chr3_184947331_ENST00000456310_length(amino acids)=1187AA_BP=581 MSTGACQALAEVHAPLGGPRPRLCALAAEGHFLGHSWTGSRAGAHTGAPAWPSRRLRDLPAGGMWRLRRAAVACEVCQSLVKHSSGIKGS LPLQKLHLVSRSIYHSHHPTLKLQRPQLRTSFQQFSSLTNLPLRKLKFSPIKYGYQPRRNFWPARLATRLLKLRYLILGSAVGGGYTAKK TFDQWKDMIPDLSEYKWIVPDIVWEIDEYIDFEKIRKALPSSEDLVKLAPDFDKIVESLSLLKDFFTSGSPEETAFRATDRGSESDKHFR KGLLGELILLQQQIQEHEEEARRAAGQYSTSYAQQKRKVSDKEKIDQLQEELLHTQLKYQRILERLEKENKELRKLVLQKDDKGIHHRKL KKSLIDMYSEVLDVLSDYDASYNTQDHLPRVVVVGDQSAGKTSVLEMIAQARIFPRGSGEMMTRSPVKVTLSEGPHHVALFKDSSREFDL TKEEDLAALRHEIELRMRKNVKEGCTVSPETISLNVKGPGLQRMVLVDLPGVINTVTSGMAPDTKETIFSISKAYMQNPNAIILCIQDGS VDAERSIVTDLVSQMDPHGRRTIFVLTKVDLAEKNVASPSRAQVGLPEVTLGLLPGARGTQLLPRLTGVPAALDLITSGRRILADEALKL GILDKVVNSDPVEEAIRFAQRVSDQPLESRRLCNKPIQSLPNMDSIFSEALLKMRRQHPGCLAQEACVRAVQAAVQYPYEVGIKKEEELF LYLLQSGQARALQYAFFAERKANKWSTPSGASWKTASARPVSSVGVVGLGTMGRGIVISFARARIPVIAVDSDKNQLATANKMITSVLEK EASKMQQSGHPWSGPKPRLTSSVKELGGVDLVIEAVFEEMSLKKQVFAELSAVCKPEAFLCTNTSALDVDEIASSTDRPHLVIGTHFFSP AHVMKLLEVIPSQYSSPTTIATVMNLSKKIKKIGVVVGNCFGFVGNRMLNPYYNQAYFLLEEGSKPEEVDQVLEEFGFKMGPFRVSDLAG LDVGWKSRKGQGLTGPTLLPGTPARKRGNRRYCPIPDVLCELGRFGQKTGKGWYQYDKPLGRIHKPDPWLSKFLSRYRKTHHIEPRTISQ DEILERCLYSLINEAFRILGEGIAASPEHIDVVYLHGYGWPRHKGGPMFYASTVGLPTVLEKLQKYYRQNPDIPQLEPSDYLKKLASQGN -------------------------------------------------------------- >61523_61523_11_OPA1-EHHADH_OPA1_chr3_193361894_ENST00000392438_EHHADH_chr3_184947331_ENST00000231887_length(transcript)=5100nt_BP=1677nt GTGCTGCCCGCCTAGAAAGGGTGAAGTGGTTGTTTCCGTGACGGACTGAGTACGGGTGCCTGTCAGGCTCTTGCGGAAGTCCATGCGCCA TTGGGAGGGCCTCGGCCGCGGCTCTGTGCCCTTGCTGCTGAGGGCCACTTCCTGGGTCATTCCTGGACCGGGAGCCGGGCTGGGGCTCAC ACGGGGGCTCCCGCGTGGCCGTCTCGGCGCCTGCGTGACCTCCCCGCCGGCGGGATGTGGCGACTACGTCGGGCCGCTGTGGCCTGTGAG GTCTGCCAGTCTTTAGTGAAACACAGCTCTGGAATAAAAGGAAGTTTACCACTACAAAAACTACATCTGGTTTCACGAAGCATTTATCAT TCACATCATCCTACCTTAAAGCTTCAACGACCCCAATTAAGGACATCCTTTCAGCAGTTCTCTTCTCTGACAAACCTTCCTTTACGTAAA CTGAAATTCTCTCCAATTAAATATGGCTACCAGCCTCGCAGGAATTTTTGGCCAGCAAGATTAGCTACGAGACTCTTAAAACTTCGCTAT CTCATACTAGGATCGGCTGTTGGGGGTGGCTACACAGCCAAAAAGACTTTTGATCAGTGGAAAGATATGATACCGGACCTTAGTGAATAT AAATGGATTGTGCCTGACATTGTGTGGGAAATTGATGAGTATATCGATTTTGAGAAAATTAGAAAAGCCCTTCCTAGTTCAGAAGACCTT GTAAAGTTAGCACCAGACTTTGACAAGATTGTTGAAAGCCTTAGCTTATTGAAGGACTTTTTTACCTCAGGTTCTCCGGAAGAAACGGCG TTTAGAGCAACAGATCGTGGATCTGAAAGTGACAAGCATTTTAGAAAGGTGTCAGACAAAGAGAAAATTGACCAACTTCAGGAAGAACTT CTGCACACTCAGTTGAAGTATCAGAGAATCTTGGAACGATTAGAAAAGGAGAACAAAGAATTGAGAAAATTAGTATTGCAGAAAGATGAC AAAGGCATTCATCATAGAAAGCTTAAGAAATCTTTGATTGACATGTATTCTGAAGTTCTTGATGTTCTCTCTGATTATGATGCCAGTTAT AATACGCAAGATCATCTGCCACGGGTTGTTGTGGTTGGAGATCAGAGTGCTGGAAAGACTAGTGTGTTGGAAATGATTGCCCAAGCTCGA ATATTCCCAAGAGGATCTGGGGAGATGATGACACGTTCTCCAGTTAAGGTGACTCTGAGTGAAGGTCCTCACCATGTGGCCCTATTTAAA GATAGTTCTCGGGAGTTTGATCTTACCAAAGAAGAAGATCTTGCAGCATTAAGACATGAAATAGAACTTCGAATGAGGAAAAATGTGAAA GAAGGCTGTACCGTTAGCCCTGAGACCATATCCTTAAATGTAAAAGGCCCTGGACTACAGAGGATGGTGCTTGTTGACTTACCAGGTGTG ATTAATACTGTGACATCAGGCATGGCTCCTGACACAAAGGAAACTATTTTCAGTATCAGCAAAGCTTACATGCAGAATCCTAATGCCATC ATACTGTGTATTCAAGATGGATCTGTGGATGCTGAACGCAGTATTGTTACAGACTTGGTCAGTCAAATGGACCCTCATGGAAGGAGAACC ATATTCGTTTTGACCAAAGTAGACCTGGCAGAGAAAAATGTAGCCAGTCCAAGCAGGGCTCAAGTTGGCTTACCAGAAGTTACACTGGGA CTTCTCCCTGGTGCAAGAGGAACCCAGCTTCTCCCCAGACTCACTGGAGTTCCTGCTGCACTTGACTTAATTACCTCAGGAAGACGTATT TTAGCAGATGAAGCACTCAAGCTGGGCATTCTAGATAAAGTTGTAAACTCAGACCCGGTTGAAGAAGCAATCAGATTTGCTCAGAGAGTT TCAGATCAACCTCTAGAATCCCGTAGACTCTGCAACAAGCCAATTCAGAGCTTGCCCAACATGGACAGCATTTTTAGTGAGGCCCTCTTG AAGATGCGGAGGCAGCACCCTGGGTGTCTTGCACAGGAGGCTTGTGTCCGTGCAGTCCAGGCTGCTGTGCAGTATCCCTATGAAGTGGGC ATCAAGAAGGAGGAGGAGCTGTTTCTATATCTTTTGCAATCAGGGCAGGCTAGAGCCCTGCAATATGCTTTCTTCGCTGAAAGGAAAGCA AATAAGTGGTCAACTCCCTCCGGAGCATCGTGGAAAACAGCATCAGCGCGGCCTGTCTCCTCAGTTGGTGTTGTTGGCTTGGGAACAATG GGCCGAGGCATTGTCATTTCTTTTGCAAGGGCCAGGATTCCTGTGATTGCTGTAGACTCGGACAAAAACCAGCTAGCAACTGCAAACAAG ATGATAACCTCTGTCTTGGAAAAAGAAGCCTCCAAAATGCAACAGAGCGGCCACCCTTGGTCAGGACCAAAACCCAGGTTAACTTCATCT GTGAAGGAGCTTGGTGGTGTAGATTTAGTCATTGAAGCAGTATTTGAGGAAATGAGCCTGAAGAAGCAGGTCTTTGCTGAACTCTCAGCT GTGTGCAAACCAGAAGCATTTTTGTGCACTAATACTTCAGCCCTGGATGTTGATGAGATTGCTTCTTCCACTGATCGTCCTCACTTGGTC ATTGGCACCCACTTCTTTTCGCCAGCTCATGTCATGAAGTTGTTAGAGGTTATTCCCAGCCAATACTCTTCCCCCACTACCATTGCCACT GTTATGAACTTATCAAAAAAGATTAAAAAGATTGGAGTCGTTGTAGGCAACTGTTTTGGATTTGTGGGGAATCGAATGTTGAATCCTTAC TACAATCAGGCATATTTCTTGTTAGAAGAAGGCAGCAAACCAGAGGAGGTAGATCAGGTGCTGGAAGAGTTTGGTTTTAAAATGGGACCT TTTAGAGTGTCTGATCTTGCTGGGTTGGATGTGGGCTGGAAATCTAGAAAGGGGCAAGGTCTTACTGGACCTACATTGCTTCCAGGAACT CCTGCCCGAAAAAGGGGTAATAGGAGGTACTGCCCAATTCCTGATGTGCTCTGTGAATTAGGACGATTTGGCCAGAAGACAGGTAAGGGT TGGTATCAATATGACAAGCCATTGGGTAGGATTCACAAACCTGATCCCTGGCTTTCCAAATTCCTATCACGGTATAGAAAAACCCATCAC ATTGAACCACGTACCATTAGCCAGGATGAGATCCTTGAACGCTGCTTATATTCACTTATCAATGAAGCATTCCGTATCTTGGGAGAAGGG ATAGCTGCTAGCCCAGAGCACATTGATGTTGTCTATTTACATGGATATGGATGGCCAAGGCACAAGGGCGGGCCCATGTTCTATGCTTCC ACAGTTGGGTTGCCCACAGTTCTAGAGAAATTGCAGAAATATTACAGGCAGAACCCTGATATTCCCCAACTGGAGCCAAGTGACTATCTA AAAAAACTGGCTTCTCAGGGAAACCCTCCCCTGAAAGAATGGCAAAGCTTGGCAGGCTCCCCTAGCAGTAAATTGTGATTCAGTCTTCCA GATTATGCCTCACATGCTAGCATCAGGTAATGCTGACTGAATTTCAGTGAAATTAAATCAAAAATCCAAAGTAAGATTGTTCTGAAATAC AAAGCAAAATAAATAATCATTAGAATCTTCTGTGTAACGACTCTAATGGTCAAATCTTTAGGAATGTGCTTCCTATGCCTCTGAATCTGT CCTTATCAGATAAATTCAATGCATGAACTTGTGTGAATATAATACCATAATAGCTAATGAAAGAGGCTCAGGCATAAGTTGAGATTCTCA AATGCTTTTATCATTGGATAAATGTGTCATCAATTAATAAATGATAAATGCAGCTAAGTCATACATTCATTTTGACTCCTTTCAATGTCA CACACATAGTATTGATCAGAAATCTTATGAATCATACATACACTCAACAAACATTAAAGTTGTAGGAAAAAGACAGTTGGAAATTGGTAA GGGAACTGAGTACTTCAAACCAGCACAGGGAACTTAGGTTAGTGTGGCAAGCCTTTCCTCTTCTGGTCTTTCCTCTTCTGTTTATGGAGA AATAATAGAAAGTAGTAAGTCGTTAACTTAGTGTAAGAAGGGTCTTAGAGAACATCTAACCTTCTAGGATTTCCCAATTCTGTGATAGAG TAATGACACCAGTTTTCCTGTCATGACAAGCCTCTGTGATGTTACATATGGAAATGGTTGAATCTTGAAAAATCTAAAATTGTTGCAAAA CATATTTTGTATGATTTTGTTGTAAGAGTTCTTCTCTTTTTACTTTTTGCCTTGTGTAGTTAAAAATTAAGGGGCTGGTCAATACAAAAA CTTGTACACAAATATTTATAGCAGAATTATTCATAATGGCCAAAAGCTGAATACAACCCAAATGTCTATGAACTAATGAATAGATAAACC AAATCTGGTATATCCATACAATGGACTATATTATTCAGCCATAAAAAGAAATAAAGGGCCAGGCACAGTGGCTCACACCTGTAATCCCAG CACTTTGGGAGGCTGAGGCAGGAGGATTGTTTGAGGCCAGAAATTTGAGACCAGCCTGGGCAACATAGCAAAACCCTGTCTCTACAAAAA ATACTTTCCGTACATTAGTGGTTGCCTAAGGCTAGAATTGGGGGTGATGAATGGGGAGTACAGGATTCATCTAATGGGTACAGGATTTCT TTATGGTTCATGAAAATGGTCTAAACTTATTGTGGTAATGGTCACATAACAATATATTAAAAACCATTGAGTTGTATATTTTAAGTGGGT GAATTATATGGTATGTGAATTATATCTCAATAAAGTTGTTAGTAAATAAATGGGGCTGAAGATGTTATCCTTCATTGTGGTGTAAATGAA CTTTCACAATATTTTCACCTGTGAACCCAAATAAAATGATTAAAGTTCTGATGGAAAAATCTTGAATGGAGTATAAGTTTTCCGTTGTTA AAAAGCAAACAAAAAACCAACAAAAAATCCAAGTGTGCCTTGAATTGTACAGAGCACAATTATTATGTTTGAAATGTGTACTACTTAATT >61523_61523_11_OPA1-EHHADH_OPA1_chr3_193361894_ENST00000392438_EHHADH_chr3_184947331_ENST00000231887_length(amino acids)=1150AA_BP=544 MSTGACQALAEVHAPLGGPRPRLCALAAEGHFLGHSWTGSRAGAHTGAPAWPSRRLRDLPAGGMWRLRRAAVACEVCQSLVKHSSGIKGS LPLQKLHLVSRSIYHSHHPTLKLQRPQLRTSFQQFSSLTNLPLRKLKFSPIKYGYQPRRNFWPARLATRLLKLRYLILGSAVGGGYTAKK TFDQWKDMIPDLSEYKWIVPDIVWEIDEYIDFEKIRKALPSSEDLVKLAPDFDKIVESLSLLKDFFTSGSPEETAFRATDRGSESDKHFR KVSDKEKIDQLQEELLHTQLKYQRILERLEKENKELRKLVLQKDDKGIHHRKLKKSLIDMYSEVLDVLSDYDASYNTQDHLPRVVVVGDQ SAGKTSVLEMIAQARIFPRGSGEMMTRSPVKVTLSEGPHHVALFKDSSREFDLTKEEDLAALRHEIELRMRKNVKEGCTVSPETISLNVK GPGLQRMVLVDLPGVINTVTSGMAPDTKETIFSISKAYMQNPNAIILCIQDGSVDAERSIVTDLVSQMDPHGRRTIFVLTKVDLAEKNVA SPSRAQVGLPEVTLGLLPGARGTQLLPRLTGVPAALDLITSGRRILADEALKLGILDKVVNSDPVEEAIRFAQRVSDQPLESRRLCNKPI QSLPNMDSIFSEALLKMRRQHPGCLAQEACVRAVQAAVQYPYEVGIKKEEELFLYLLQSGQARALQYAFFAERKANKWSTPSGASWKTAS ARPVSSVGVVGLGTMGRGIVISFARARIPVIAVDSDKNQLATANKMITSVLEKEASKMQQSGHPWSGPKPRLTSSVKELGGVDLVIEAVF EEMSLKKQVFAELSAVCKPEAFLCTNTSALDVDEIASSTDRPHLVIGTHFFSPAHVMKLLEVIPSQYSSPTTIATVMNLSKKIKKIGVVV GNCFGFVGNRMLNPYYNQAYFLLEEGSKPEEVDQVLEEFGFKMGPFRVSDLAGLDVGWKSRKGQGLTGPTLLPGTPARKRGNRRYCPIPD VLCELGRFGQKTGKGWYQYDKPLGRIHKPDPWLSKFLSRYRKTHHIEPRTISQDEILERCLYSLINEAFRILGEGIAASPEHIDVVYLHG -------------------------------------------------------------- >61523_61523_12_OPA1-EHHADH_OPA1_chr3_193361894_ENST00000392438_EHHADH_chr3_184947331_ENST00000456310_length(transcript)=3754nt_BP=1677nt GTGCTGCCCGCCTAGAAAGGGTGAAGTGGTTGTTTCCGTGACGGACTGAGTACGGGTGCCTGTCAGGCTCTTGCGGAAGTCCATGCGCCA TTGGGAGGGCCTCGGCCGCGGCTCTGTGCCCTTGCTGCTGAGGGCCACTTCCTGGGTCATTCCTGGACCGGGAGCCGGGCTGGGGCTCAC ACGGGGGCTCCCGCGTGGCCGTCTCGGCGCCTGCGTGACCTCCCCGCCGGCGGGATGTGGCGACTACGTCGGGCCGCTGTGGCCTGTGAG GTCTGCCAGTCTTTAGTGAAACACAGCTCTGGAATAAAAGGAAGTTTACCACTACAAAAACTACATCTGGTTTCACGAAGCATTTATCAT TCACATCATCCTACCTTAAAGCTTCAACGACCCCAATTAAGGACATCCTTTCAGCAGTTCTCTTCTCTGACAAACCTTCCTTTACGTAAA CTGAAATTCTCTCCAATTAAATATGGCTACCAGCCTCGCAGGAATTTTTGGCCAGCAAGATTAGCTACGAGACTCTTAAAACTTCGCTAT CTCATACTAGGATCGGCTGTTGGGGGTGGCTACACAGCCAAAAAGACTTTTGATCAGTGGAAAGATATGATACCGGACCTTAGTGAATAT AAATGGATTGTGCCTGACATTGTGTGGGAAATTGATGAGTATATCGATTTTGAGAAAATTAGAAAAGCCCTTCCTAGTTCAGAAGACCTT GTAAAGTTAGCACCAGACTTTGACAAGATTGTTGAAAGCCTTAGCTTATTGAAGGACTTTTTTACCTCAGGTTCTCCGGAAGAAACGGCG TTTAGAGCAACAGATCGTGGATCTGAAAGTGACAAGCATTTTAGAAAGGTGTCAGACAAAGAGAAAATTGACCAACTTCAGGAAGAACTT CTGCACACTCAGTTGAAGTATCAGAGAATCTTGGAACGATTAGAAAAGGAGAACAAAGAATTGAGAAAATTAGTATTGCAGAAAGATGAC AAAGGCATTCATCATAGAAAGCTTAAGAAATCTTTGATTGACATGTATTCTGAAGTTCTTGATGTTCTCTCTGATTATGATGCCAGTTAT AATACGCAAGATCATCTGCCACGGGTTGTTGTGGTTGGAGATCAGAGTGCTGGAAAGACTAGTGTGTTGGAAATGATTGCCCAAGCTCGA ATATTCCCAAGAGGATCTGGGGAGATGATGACACGTTCTCCAGTTAAGGTGACTCTGAGTGAAGGTCCTCACCATGTGGCCCTATTTAAA GATAGTTCTCGGGAGTTTGATCTTACCAAAGAAGAAGATCTTGCAGCATTAAGACATGAAATAGAACTTCGAATGAGGAAAAATGTGAAA GAAGGCTGTACCGTTAGCCCTGAGACCATATCCTTAAATGTAAAAGGCCCTGGACTACAGAGGATGGTGCTTGTTGACTTACCAGGTGTG ATTAATACTGTGACATCAGGCATGGCTCCTGACACAAAGGAAACTATTTTCAGTATCAGCAAAGCTTACATGCAGAATCCTAATGCCATC ATACTGTGTATTCAAGATGGATCTGTGGATGCTGAACGCAGTATTGTTACAGACTTGGTCAGTCAAATGGACCCTCATGGAAGGAGAACC ATATTCGTTTTGACCAAAGTAGACCTGGCAGAGAAAAATGTAGCCAGTCCAAGCAGGGCTCAAGTTGGCTTACCAGAAGTTACACTGGGA CTTCTCCCTGGTGCAAGAGGAACCCAGCTTCTCCCCAGACTCACTGGAGTTCCTGCTGCACTTGACTTAATTACCTCAGGAAGACGTATT TTAGCAGATGAAGCACTCAAGCTGGGCATTCTAGATAAAGTTGTAAACTCAGACCCGGTTGAAGAAGCAATCAGATTTGCTCAGAGAGTT TCAGATCAACCTCTAGAATCCCGTAGACTCTGCAACAAGCCAATTCAGAGCTTGCCCAACATGGACAGCATTTTTAGTGAGGCCCTCTTG AAGATGCGGAGGCAGCACCCTGGGTGTCTTGCACAGGAGGCTTGTGTCCGTGCAGTCCAGGCTGCTGTGCAGTATCCCTATGAAGTGGGC ATCAAGAAGGAGGAGGAGCTGTTTCTATATCTTTTGCAATCAGGGCAGGCTAGAGCCCTGCAATATGCTTTCTTCGCTGAAAGGAAAGCA AATAAGTGGTCAACTCCCTCCGGAGCATCGTGGAAAACAGCATCAGCGCGGCCTGTCTCCTCAGTTGGTGTTGTTGGCTTGGGAACAATG GGCCGAGGCATTGTCATTTCTTTTGCAAGGGCCAGGATTCCTGTGATTGCTGTAGACTCGGACAAAAACCAGCTAGCAACTGCAAACAAG ATGATAACCTCTGTCTTGGAAAAAGAAGCCTCCAAAATGCAACAGAGCGGCCACCCTTGGTCAGGACCAAAACCCAGGTTAACTTCATCT GTGAAGGAGCTTGGTGGTGTAGATTTAGTCATTGAAGCAGTATTTGAGGAAATGAGCCTGAAGAAGCAGGTCTTTGCTGAACTCTCAGCT GTGTGCAAACCAGAAGCATTTTTGTGCACTAATACTTCAGCCCTGGATGTTGATGAGATTGCTTCTTCCACTGATCGTCCTCACTTGGTC ATTGGCACCCACTTCTTTTCGCCAGCTCATGTCATGAAGTTGTTAGAGGTTATTCCCAGCCAATACTCTTCCCCCACTACCATTGCCACT GTTATGAACTTATCAAAAAAGATTAAAAAGATTGGAGTCGTTGTAGGCAACTGTTTTGGATTTGTGGGGAATCGAATGTTGAATCCTTAC TACAATCAGGCATATTTCTTGTTAGAAGAAGGCAGCAAACCAGAGGAGGTAGATCAGGTGCTGGAAGAGTTTGGTTTTAAAATGGGACCT TTTAGAGTGTCTGATCTTGCTGGGTTGGATGTGGGCTGGAAATCTAGAAAGGGGCAAGGTCTTACTGGACCTACATTGCTTCCAGGAACT CCTGCCCGAAAAAGGGGTAATAGGAGGTACTGCCCAATTCCTGATGTGCTCTGTGAATTAGGACGATTTGGCCAGAAGACAGGTAAGGGT TGGTATCAATATGACAAGCCATTGGGTAGGATTCACAAACCTGATCCCTGGCTTTCCAAATTCCTATCACGGTATAGAAAAACCCATCAC ATTGAACCACGTACCATTAGCCAGGATGAGATCCTTGAACGCTGCTTATATTCACTTATCAATGAAGCATTCCGTATCTTGGGAGAAGGG ATAGCTGCTAGCCCAGAGCACATTGATGTTGTCTATTTACATGGATATGGATGGCCAAGGCACAAGGGCGGGCCCATGTTCTATGCTTCC ACAGTTGGGTTGCCCACAGTTCTAGAGAAATTGCAGAAATATTACAGGCAGAACCCTGATATTCCCCAACTGGAGCCAAGTGACTATCTA AAAAAACTGGCTTCTCAGGGAAACCCTCCCCTGAAAGAATGGCAAAGCTTGGCAGGCTCCCCTAGCAGTAAATTGTGATTCAGTCTTCCA GATTATGCCTCACATGCTAGCATCAGGTAATGCTGACTGAATTTCAGTGAAATTAAATCAAAAATCCAAAGTAAGATTGTTCTGAAATAC AAAGCAAAATAAATAATCATTAGAATCTTCTGTGTAACGACTCTAATGGTCAAATCTTTAGGAATGTGCTTCCTATGCCTCTGAATCTGT >61523_61523_12_OPA1-EHHADH_OPA1_chr3_193361894_ENST00000392438_EHHADH_chr3_184947331_ENST00000456310_length(amino acids)=1150AA_BP=544 MSTGACQALAEVHAPLGGPRPRLCALAAEGHFLGHSWTGSRAGAHTGAPAWPSRRLRDLPAGGMWRLRRAAVACEVCQSLVKHSSGIKGS LPLQKLHLVSRSIYHSHHPTLKLQRPQLRTSFQQFSSLTNLPLRKLKFSPIKYGYQPRRNFWPARLATRLLKLRYLILGSAVGGGYTAKK TFDQWKDMIPDLSEYKWIVPDIVWEIDEYIDFEKIRKALPSSEDLVKLAPDFDKIVESLSLLKDFFTSGSPEETAFRATDRGSESDKHFR KVSDKEKIDQLQEELLHTQLKYQRILERLEKENKELRKLVLQKDDKGIHHRKLKKSLIDMYSEVLDVLSDYDASYNTQDHLPRVVVVGDQ SAGKTSVLEMIAQARIFPRGSGEMMTRSPVKVTLSEGPHHVALFKDSSREFDLTKEEDLAALRHEIELRMRKNVKEGCTVSPETISLNVK GPGLQRMVLVDLPGVINTVTSGMAPDTKETIFSISKAYMQNPNAIILCIQDGSVDAERSIVTDLVSQMDPHGRRTIFVLTKVDLAEKNVA SPSRAQVGLPEVTLGLLPGARGTQLLPRLTGVPAALDLITSGRRILADEALKLGILDKVVNSDPVEEAIRFAQRVSDQPLESRRLCNKPI QSLPNMDSIFSEALLKMRRQHPGCLAQEACVRAVQAAVQYPYEVGIKKEEELFLYLLQSGQARALQYAFFAERKANKWSTPSGASWKTAS ARPVSSVGVVGLGTMGRGIVISFARARIPVIAVDSDKNQLATANKMITSVLEKEASKMQQSGHPWSGPKPRLTSSVKELGGVDLVIEAVF EEMSLKKQVFAELSAVCKPEAFLCTNTSALDVDEIASSTDRPHLVIGTHFFSPAHVMKLLEVIPSQYSSPTTIATVMNLSKKIKKIGVVV GNCFGFVGNRMLNPYYNQAYFLLEEGSKPEEVDQVLEEFGFKMGPFRVSDLAGLDVGWKSRKGQGLTGPTLLPGTPARKRGNRRYCPIPD VLCELGRFGQKTGKGWYQYDKPLGRIHKPDPWLSKFLSRYRKTHHIEPRTISQDEILERCLYSLINEAFRILGEGIAASPEHIDVVYLHG -------------------------------------------------------------- |
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Fusion Gene PPI Analysis for OPA1-EHHADH |
| Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in |
| Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160) |
| Hgene | Hgene's interactors | Tgene | Tgene's interactors |
| - Retained PPIs in in-frame fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Still interaction with |
| - Lost PPIs in in-frame fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Interaction lost with |
| - Retained PPIs, but lost function due to frame-shift fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Interaction lost with |
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Related Drugs for OPA1-EHHADH |
| Drugs targeting genes involved in this fusion gene. (DrugBank Version 5.1.8 2021-05-08) |
| Partner | Gene | UniProtAcc | DrugBank ID | Drug name | Drug activity | Drug type | Drug status |
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Related Diseases for OPA1-EHHADH |
| Diseases associated with fusion partners. (DisGeNet 4.0) |
| Partner | Gene | Disease ID | Disease name | # pubmeds | Source |
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