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Center for Computational Systems Medicine
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Fusion Gene Summary

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Fusion Gene ORF analysis

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Fusion Genomic Features

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Fusion Protein Features

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Fusion Gene Sequence

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Fusion Gene PPI analysis

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Related Drugs

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Related Diseases

Fusion gene:OSBP2-MRPL43 (FusionGDB2 ID:61751)

Fusion Gene Summary for OSBP2-MRPL43

check button Fusion gene summary
Fusion gene informationFusion gene name: OSBP2-MRPL43
Fusion gene ID: 61751
HgeneTgene
Gene symbol

OSBP2

MRPL43

Gene ID

23762

84545

Gene nameoxysterol binding protein 2mitochondrial ribosomal protein L43
SynonymsHLM|ORP-4|ORP4|OSBPL1|OSBPL4L43mt|MRP-L43|bMRP36a
Cytomap

22q12.2

10q24.31

Type of geneprotein-codingprotein-coding
Descriptionoxysterol-binding protein 2OSBP-related protein 4oxysterol binding protein-like 1oxysterol-binding protein-related protein 439S ribosomal protein L43, mitochondrialmitochondrial large ribosomal subunit protein mL43mitochondrial ribosomal protein bMRP36a
Modification date2020031320200320
UniProtAcc.

Q8N983

Ensembl transtripts involved in fusion geneENST00000332585, ENST00000382310, 
ENST00000403222, ENST00000407373, 
ENST00000446658, ENST00000401475, 
ENST00000437268, ENST00000496575, 
ENST00000535268, 		ENST00000318364, 
ENST00000370234, ENST00000370236, 
ENST00000477279, ENST00000493646, 
ENST00000299179, ENST00000318325, 
ENST00000370241, ENST00000342071, 
ENST00000370242, 
Fusion gene scores* DoF score18 X 13 X 7=16381 X 1 X 1=1
# samples 181
** MAII scorelog2(18/1638*10)=-3.18586654531133
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0		log2(1/1*10)=3.32192809488736
Context

PubMed: OSBP2 [Title/Abstract] AND MRPL43 [Title/Abstract] AND fusion [Title/Abstract]

Most frequent breakpointOSBP2(31137356)-MRPL43(102743574), # samples:3
Anticipated loss of major functional domain due to fusion event.OSBP2-MRPL43 seems lost the major protein functional domain in Tgene partner, which is a essential gene due to the frame-shifted ORF.
* DoF score (Degree of Frequency) = # partners X # break points X # cancer types
** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)

check button Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez
PartnerGeneGO IDGO termPubMed ID

check buttonFusion gene breakpoints across OSBP2 (5'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check buttonFusion gene breakpoints across MRPL43 (3'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check button Fusion gene information from two resources (ChiTars 5.0 and ChimerDB 4.0)
* All genome coordinats were lifted-over on hg19.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
SourceDiseaseSampleHgeneHchrHbpHstrandTgeneTchrTbpTstrand
ChimerDB4SKCMTCGA-EB-A42Z-01AOSBP2chr22

31137356

-MRPL43chr10

102743574

-
ChimerDB4SKCMTCGA-EB-A42Z-01AOSBP2chr22

31137356

+MRPL43chr10

102743574

-


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Fusion Gene ORF analysis for OSBP2-MRPL43

check button Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
ORFHenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrand
5CDS-intronENST00000332585ENST00000318364OSBP2chr22

31137356

+MRPL43chr10

102743574

-
5CDS-intronENST00000332585ENST00000370234OSBP2chr22

31137356

+MRPL43chr10

102743574

-
5CDS-intronENST00000332585ENST00000370236OSBP2chr22

31137356

+MRPL43chr10

102743574

-
5CDS-intronENST00000332585ENST00000477279OSBP2chr22

31137356

+MRPL43chr10

102743574

-
5CDS-intronENST00000332585ENST00000493646OSBP2chr22

31137356

+MRPL43chr10

102743574

-
5CDS-intronENST00000382310ENST00000318364OSBP2chr22

31137356

+MRPL43chr10

102743574

-
5CDS-intronENST00000382310ENST00000370234OSBP2chr22

31137356

+MRPL43chr10

102743574

-
5CDS-intronENST00000382310ENST00000370236OSBP2chr22

31137356

+MRPL43chr10

102743574

-
5CDS-intronENST00000382310ENST00000477279OSBP2chr22

31137356

+MRPL43chr10

102743574

-
5CDS-intronENST00000382310ENST00000493646OSBP2chr22

31137356

+MRPL43chr10

102743574

-
5CDS-intronENST00000403222ENST00000318364OSBP2chr22

31137356

+MRPL43chr10

102743574

-
5CDS-intronENST00000403222ENST00000370234OSBP2chr22

31137356

+MRPL43chr10

102743574

-
5CDS-intronENST00000403222ENST00000370236OSBP2chr22

31137356

+MRPL43chr10

102743574

-
5CDS-intronENST00000403222ENST00000477279OSBP2chr22

31137356

+MRPL43chr10

102743574

-
5CDS-intronENST00000403222ENST00000493646OSBP2chr22

31137356

+MRPL43chr10

102743574

-
5CDS-intronENST00000407373ENST00000318364OSBP2chr22

31137356

+MRPL43chr10

102743574

-
5CDS-intronENST00000407373ENST00000370234OSBP2chr22

31137356

+MRPL43chr10

102743574

-
5CDS-intronENST00000407373ENST00000370236OSBP2chr22

31137356

+MRPL43chr10

102743574

-
5CDS-intronENST00000407373ENST00000477279OSBP2chr22

31137356

+MRPL43chr10

102743574

-
5CDS-intronENST00000407373ENST00000493646OSBP2chr22

31137356

+MRPL43chr10

102743574

-
5CDS-intronENST00000446658ENST00000318364OSBP2chr22

31137356

+MRPL43chr10

102743574

-
5CDS-intronENST00000446658ENST00000370234OSBP2chr22

31137356

+MRPL43chr10

102743574

-
5CDS-intronENST00000446658ENST00000370236OSBP2chr22

31137356

+MRPL43chr10

102743574

-
5CDS-intronENST00000446658ENST00000477279OSBP2chr22

31137356

+MRPL43chr10

102743574

-
5CDS-intronENST00000446658ENST00000493646OSBP2chr22

31137356

+MRPL43chr10

102743574

-
Frame-shiftENST00000332585ENST00000299179OSBP2chr22

31137356

+MRPL43chr10

102743574

-
Frame-shiftENST00000332585ENST00000318325OSBP2chr22

31137356

+MRPL43chr10

102743574

-
Frame-shiftENST00000332585ENST00000370241OSBP2chr22

31137356

+MRPL43chr10

102743574

-
Frame-shiftENST00000382310ENST00000299179OSBP2chr22

31137356

+MRPL43chr10

102743574

-
Frame-shiftENST00000382310ENST00000318325OSBP2chr22

31137356

+MRPL43chr10

102743574

-
Frame-shiftENST00000382310ENST00000370241OSBP2chr22

31137356

+MRPL43chr10

102743574

-
Frame-shiftENST00000403222ENST00000299179OSBP2chr22

31137356

+MRPL43chr10

102743574

-
Frame-shiftENST00000403222ENST00000318325OSBP2chr22

31137356

+MRPL43chr10

102743574

-
Frame-shiftENST00000403222ENST00000370241OSBP2chr22

31137356

+MRPL43chr10

102743574

-
Frame-shiftENST00000407373ENST00000299179OSBP2chr22

31137356

+MRPL43chr10

102743574

-
Frame-shiftENST00000407373ENST00000318325OSBP2chr22

31137356

+MRPL43chr10

102743574

-
Frame-shiftENST00000407373ENST00000370241OSBP2chr22

31137356

+MRPL43chr10

102743574

-
Frame-shiftENST00000446658ENST00000299179OSBP2chr22

31137356

+MRPL43chr10

102743574

-
Frame-shiftENST00000446658ENST00000318325OSBP2chr22

31137356

+MRPL43chr10

102743574

-
Frame-shiftENST00000446658ENST00000370241OSBP2chr22

31137356

+MRPL43chr10

102743574

-
In-frameENST00000332585ENST00000342071OSBP2chr22

31137356

+MRPL43chr10

102743574

-
In-frameENST00000332585ENST00000370242OSBP2chr22

31137356

+MRPL43chr10

102743574

-
In-frameENST00000382310ENST00000342071OSBP2chr22

31137356

+MRPL43chr10

102743574

-
In-frameENST00000382310ENST00000370242OSBP2chr22

31137356

+MRPL43chr10

102743574

-
In-frameENST00000403222ENST00000342071OSBP2chr22

31137356

+MRPL43chr10

102743574

-
In-frameENST00000403222ENST00000370242OSBP2chr22

31137356

+MRPL43chr10

102743574

-
In-frameENST00000407373ENST00000342071OSBP2chr22

31137356

+MRPL43chr10

102743574

-
In-frameENST00000407373ENST00000370242OSBP2chr22

31137356

+MRPL43chr10

102743574

-
In-frameENST00000446658ENST00000342071OSBP2chr22

31137356

+MRPL43chr10

102743574

-
In-frameENST00000446658ENST00000370242OSBP2chr22

31137356

+MRPL43chr10

102743574

-
intron-3CDSENST00000401475ENST00000299179OSBP2chr22

31137356

+MRPL43chr10

102743574

-
intron-3CDSENST00000401475ENST00000318325OSBP2chr22

31137356

+MRPL43chr10

102743574

-
intron-3CDSENST00000401475ENST00000342071OSBP2chr22

31137356

+MRPL43chr10

102743574

-
intron-3CDSENST00000401475ENST00000370241OSBP2chr22

31137356

+MRPL43chr10

102743574

-
intron-3CDSENST00000401475ENST00000370242OSBP2chr22

31137356

+MRPL43chr10

102743574

-
intron-3CDSENST00000437268ENST00000299179OSBP2chr22

31137356

+MRPL43chr10

102743574

-
intron-3CDSENST00000437268ENST00000318325OSBP2chr22

31137356

+MRPL43chr10

102743574

-
intron-3CDSENST00000437268ENST00000342071OSBP2chr22

31137356

+MRPL43chr10

102743574

-
intron-3CDSENST00000437268ENST00000370241OSBP2chr22

31137356

+MRPL43chr10

102743574

-
intron-3CDSENST00000437268ENST00000370242OSBP2chr22

31137356

+MRPL43chr10

102743574

-
intron-3CDSENST00000496575ENST00000299179OSBP2chr22

31137356

+MRPL43chr10

102743574

-
intron-3CDSENST00000496575ENST00000318325OSBP2chr22

31137356

+MRPL43chr10

102743574

-
intron-3CDSENST00000496575ENST00000342071OSBP2chr22

31137356

+MRPL43chr10

102743574

-
intron-3CDSENST00000496575ENST00000370241OSBP2chr22

31137356

+MRPL43chr10

102743574

-
intron-3CDSENST00000496575ENST00000370242OSBP2chr22

31137356

+MRPL43chr10

102743574

-
intron-3CDSENST00000535268ENST00000299179OSBP2chr22

31137356

+MRPL43chr10

102743574

-
intron-3CDSENST00000535268ENST00000318325OSBP2chr22

31137356

+MRPL43chr10

102743574

-
intron-3CDSENST00000535268ENST00000342071OSBP2chr22

31137356

+MRPL43chr10

102743574

-
intron-3CDSENST00000535268ENST00000370241OSBP2chr22

31137356

+MRPL43chr10

102743574

-
intron-3CDSENST00000535268ENST00000370242OSBP2chr22

31137356

+MRPL43chr10

102743574

-
intron-intronENST00000401475ENST00000318364OSBP2chr22

31137356

+MRPL43chr10

102743574

-
intron-intronENST00000401475ENST00000370234OSBP2chr22

31137356

+MRPL43chr10

102743574

-
intron-intronENST00000401475ENST00000370236OSBP2chr22

31137356

+MRPL43chr10

102743574

-
intron-intronENST00000401475ENST00000477279OSBP2chr22

31137356

+MRPL43chr10

102743574

-
intron-intronENST00000401475ENST00000493646OSBP2chr22

31137356

+MRPL43chr10

102743574

-
intron-intronENST00000437268ENST00000318364OSBP2chr22

31137356

+MRPL43chr10

102743574

-
intron-intronENST00000437268ENST00000370234OSBP2chr22

31137356

+MRPL43chr10

102743574

-
intron-intronENST00000437268ENST00000370236OSBP2chr22

31137356

+MRPL43chr10

102743574

-
intron-intronENST00000437268ENST00000477279OSBP2chr22

31137356

+MRPL43chr10

102743574

-
intron-intronENST00000437268ENST00000493646OSBP2chr22

31137356

+MRPL43chr10

102743574

-
intron-intronENST00000496575ENST00000318364OSBP2chr22

31137356

+MRPL43chr10

102743574

-
intron-intronENST00000496575ENST00000370234OSBP2chr22

31137356

+MRPL43chr10

102743574

-
intron-intronENST00000496575ENST00000370236OSBP2chr22

31137356

+MRPL43chr10

102743574

-
intron-intronENST00000496575ENST00000477279OSBP2chr22

31137356

+MRPL43chr10

102743574

-
intron-intronENST00000496575ENST00000493646OSBP2chr22

31137356

+MRPL43chr10

102743574

-
intron-intronENST00000535268ENST00000318364OSBP2chr22

31137356

+MRPL43chr10

102743574

-
intron-intronENST00000535268ENST00000370234OSBP2chr22

31137356

+MRPL43chr10

102743574

-
intron-intronENST00000535268ENST00000370236OSBP2chr22

31137356

+MRPL43chr10

102743574

-
intron-intronENST00000535268ENST00000477279OSBP2chr22

31137356

+MRPL43chr10

102743574

-
intron-intronENST00000535268ENST00000493646OSBP2chr22

31137356

+MRPL43chr10

102743574

-

check buttonORFfinder result based on the fusion transcript sequence of in-frame fusion genes.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandSeq length
(transcript)		BP loci
(transcript)		Predicted start
(transcript)		Predicted stop
(transcript)		Seq length
(amino acids)
ENST00000403222OSBP2chr2231137356+ENST00000370242MRPL43chr10102743574-875637144830228
ENST00000403222OSBP2chr2231137356+ENST00000342071MRPL43chr10102743574-867637144752202
ENST00000407373OSBP2chr2231137356+ENST00000370242MRPL43chr10102743574-716478144671175
ENST00000407373OSBP2chr2231137356+ENST00000342071MRPL43chr10102743574-708478144593149
ENST00000332585OSBP2chr2231137356+ENST00000370242MRPL43chr10102743574-1195957531150365
ENST00000332585OSBP2chr2231137356+ENST00000342071MRPL43chr10102743574-1187957531072339
ENST00000382310OSBP2chr2231137356+ENST00000370242MRPL43chr10102743574-1127889361082348
ENST00000382310OSBP2chr2231137356+ENST00000342071MRPL43chr10102743574-1119889361004322
ENST00000446658OSBP2chr2231137356+ENST00000370242MRPL43chr10102743574-1112874211067348
ENST00000446658OSBP2chr2231137356+ENST00000342071MRPL43chr10102743574-110487421989322

check buttonDeepORF prediction of the coding potential based on the fusion transcript sequence of in-frame fusion genes. DeepORF is a coding potential classifier based on convolutional neural network by comparing the real Ribo-seq data. If the no-coding score < 0.5 and coding score > 0.5, then the in-frame fusion transcript is predicted as being likely translated.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandNo-coding scoreCoding score
ENST00000403222ENST00000370242OSBP2chr2231137356+MRPL43chr10102743574-0.104482190.89551777
ENST00000403222ENST00000342071OSBP2chr2231137356+MRPL43chr10102743574-0.297015520.7029845
ENST00000407373ENST00000370242OSBP2chr2231137356+MRPL43chr10102743574-0.092685010.907315
ENST00000407373ENST00000342071OSBP2chr2231137356+MRPL43chr10102743574-0.341458350.6585417
ENST00000332585ENST00000370242OSBP2chr2231137356+MRPL43chr10102743574-0.16128970.8387103
ENST00000332585ENST00000342071OSBP2chr2231137356+MRPL43chr10102743574-0.268789140.7312108
ENST00000382310ENST00000370242OSBP2chr2231137356+MRPL43chr10102743574-0.153357310.8466426
ENST00000382310ENST00000342071OSBP2chr2231137356+MRPL43chr10102743574-0.255656030.744344
ENST00000446658ENST00000370242OSBP2chr2231137356+MRPL43chr10102743574-0.161631660.83836836
ENST00000446658ENST00000342071OSBP2chr2231137356+MRPL43chr10102743574-0.266633060.73336697

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Fusion Genomic Features for OSBP2-MRPL43


check buttonFusionAI prediction of the potential fusion gene breakpoint based on the pre-mature RNA sequence context (+/- 5kb of individual partner genes, total 20kb length sequence). FusionAI is a fusion gene breakpoint classifier based on convolutional neural network by comparing the fusion positive and negative sequence context of ~ 20K fusion gene data. From here, we can have the relative potentency of the 20K genomic sequence how individual sequnce will be likely used as the gene fusion breakpoints.
HgeneHchrHbpHstrandTgeneTchrTbpTstrand1-pp (fusion gene breakpoint)

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions. We integrated a total of 44 different types of human genomic feature loci information across five big categories including virus integration sites, repeats, structural variants, chromatin states, and gene expression regulation. More details are in help page.
genomic feature

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions that are ovelapped with the top 1% feature importance score regions. More details are in help page.

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Fusion Protein Features for OSBP2-MRPL43


check button Four levels of functional features of fusion genes
Go to FGviewer search page for the most frequent breakpoint (https://ccsmweb.uth.edu/FGviewer/chr22:31137356/chr10:102743574)
- FGviewer provides the online visualization of the retention search of the protein functional features across DNA, RNA, protein, and pathological levels.
- How to search
1. Put your fusion gene symbol.
2. Press the tab key until there will be shown the breakpoint information filled.
4. Go down and press 'Search' tab twice.
4. Go down to have the hyperlink of the search result.
5. Click the hyperlink.
6. See the FGviewer result for your fusion gene.
FGviewer

check buttonMain function of each fusion partner protein. (from UniProt)
HgeneTgene
.MRPL43

Q8N983

FUNCTION: Transcriptional activator which is required for calcium-dependent dendritic growth and branching in cortical neurons. Recruits CREB-binding protein (CREBBP) to nuclear bodies. Component of the CREST-BRG1 complex, a multiprotein complex that regulates promoter activation by orchestrating a calcium-dependent release of a repressor complex and a recruitment of an activator complex. In resting neurons, transcription of the c-FOS promoter is inhibited by BRG1-dependent recruitment of a phospho-RB1-HDAC1 repressor complex. Upon calcium influx, RB1 is dephosphorylated by calcineurin, which leads to release of the repressor complex. At the same time, there is increased recruitment of CREBBP to the promoter by a CREST-dependent mechanism, which leads to transcriptional activation. The CREST-BRG1 complex also binds to the NR2B promoter, and activity-dependent induction of NR2B expression involves a release of HDAC1 and recruitment of CREBBP (By similarity). {ECO:0000250}.

check buttonRetention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at

download page


* Minus value of BPloci means that the break pointn is located before the CDS.
- In-frame and retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneOSBP2chr22:31137356chr10:102743574ENST00000332585+214182_274284917.0DomainPH

- In-frame and not-retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note


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Fusion Gene Sequence for OSBP2-MRPL43


check button For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. To have fusion amino acid sequence, we ran ORFfinder and chose the longest ORF among the all predicted ones.
>61751_61751_1_OSBP2-MRPL43_OSBP2_chr22_31137356_ENST00000332585_MRPL43_chr10_102743574_ENST00000342071_length(transcript)=1187nt_BP=957nt
GCCCCCGCCTCGCGCCGCGCGCACGTGACTGCGCCCCCGGCCCCGCCCCCGGCCTGCCCCCCGCCCCCACTGGCCGCTCGGCCGCGCGCG
GGTCGGCCGGCTCTATGGGGAAAGCGGCGGCTCCGAGCCGAGGCGGCGGCTGTGGCGGCCGCTCCCGCGGGCTCTCGTCGCTGTTCACGG
TTGTCCCCTGCCTGTCGTGCCACACGGCGGCGCCGGGCATGAGCGCTTCCACGTCCGGCTCCGGGCCGGAGCCCAAGCCCCAGCCCCAGC
CCGTGCCCGAACCGGAGCGGGGACCGCTGTCAGAACAGGTGTCGGAGGCAGTTTCGGAGGCAGTGCCAAGATCGGAACCTGTGTCCGAGA
CGACGTCTGAGCCGGAGCCAGGGGCTGGGCAGCCATCGGAACTGCTGCAGGGGTCGCGGCCGGGGTCAGAGTCAAGCTCAGGTGTAGGGG
CTGGGCCCTTCACTAAGGCCGCATCGGAGCCGCTCTCCCGGGCGGTGGGGAGCGCGACCTTTCTCAGACCCGAGTCAGGATCGCTGCCAG
CGTTAAAGCCCCTGCCTCTTCTGCGACCAGGACAGGCGAAGACTCCTCTTGGGGTTCCAATGTCGGGGACTGGCACGACCTCCAGTGCCC
CACTGGCCTTACTGCCTCTGGACAGCTTCGAGGGCTGGCTTCTCAAGTGGACCAACTATCTGAAGGGCTACCAGCGCCGCTGGTTCGTGC
TGGGCAATGGTTTGCTCTCTTACTACAGAAATCAGGGTGAAATGGCCCACACGTGCCGTGGAACCATCAACCTGTCCACCGCGCACATTG
ACACGGAGGACTCTTGTGGTATCTTGCTGACCAGTGGGGCCAGGAGCTACCACCTCAAGGCCAGCTCAGAGGTGGACCGGCAGCAGTGGA
TCACCGCCCTGGAGCTGGCCAAGGCCAAGGCTGTCCGCGTGATGAACACTCATTCAGGACACTGGCCTGAGACTGTCTGCAGTTGCACCG
CAGATCCTCCTGCCCGGCTGGCCCGACCCAATATCAGTTCAGTCATCCGATCTTCCTTGGGGAAATACCCATTACCGTCCTGAACCCTTG
TCATCCACTACTTGGCTATAAGCTCCAGAAGTGACAAGACACTTCACATCTTAAATATGTTTCCTAGTTTATAATTCATTTGGGCAGTAA

>61751_61751_1_OSBP2-MRPL43_OSBP2_chr22_31137356_ENST00000332585_MRPL43_chr10_102743574_ENST00000342071_length(amino acids)=339AA_BP=301
MPPAPTGRSAARGSAGSMGKAAAPSRGGGCGGRSRGLSSLFTVVPCLSCHTAAPGMSASTSGSGPEPKPQPQPVPEPERGPLSEQVSEAV
SEAVPRSEPVSETTSEPEPGAGQPSELLQGSRPGSESSSGVGAGPFTKAASEPLSRAVGSATFLRPESGSLPALKPLPLLRPGQAKTPLG
VPMSGTGTTSSAPLALLPLDSFEGWLLKWTNYLKGYQRRWFVLGNGLLSYYRNQGEMAHTCRGTINLSTAHIDTEDSCGILLTSGARSYH

--------------------------------------------------------------
>61751_61751_2_OSBP2-MRPL43_OSBP2_chr22_31137356_ENST00000332585_MRPL43_chr10_102743574_ENST00000370242_length(transcript)=1195nt_BP=957nt
GCCCCCGCCTCGCGCCGCGCGCACGTGACTGCGCCCCCGGCCCCGCCCCCGGCCTGCCCCCCGCCCCCACTGGCCGCTCGGCCGCGCGCG
GGTCGGCCGGCTCTATGGGGAAAGCGGCGGCTCCGAGCCGAGGCGGCGGCTGTGGCGGCCGCTCCCGCGGGCTCTCGTCGCTGTTCACGG
TTGTCCCCTGCCTGTCGTGCCACACGGCGGCGCCGGGCATGAGCGCTTCCACGTCCGGCTCCGGGCCGGAGCCCAAGCCCCAGCCCCAGC
CCGTGCCCGAACCGGAGCGGGGACCGCTGTCAGAACAGGTGTCGGAGGCAGTTTCGGAGGCAGTGCCAAGATCGGAACCTGTGTCCGAGA
CGACGTCTGAGCCGGAGCCAGGGGCTGGGCAGCCATCGGAACTGCTGCAGGGGTCGCGGCCGGGGTCAGAGTCAAGCTCAGGTGTAGGGG
CTGGGCCCTTCACTAAGGCCGCATCGGAGCCGCTCTCCCGGGCGGTGGGGAGCGCGACCTTTCTCAGACCCGAGTCAGGATCGCTGCCAG
CGTTAAAGCCCCTGCCTCTTCTGCGACCAGGACAGGCGAAGACTCCTCTTGGGGTTCCAATGTCGGGGACTGGCACGACCTCCAGTGCCC
CACTGGCCTTACTGCCTCTGGACAGCTTCGAGGGCTGGCTTCTCAAGTGGACCAACTATCTGAAGGGCTACCAGCGCCGCTGGTTCGTGC
TGGGCAATGGTTTGCTCTCTTACTACAGAAATCAGGGTGAAATGGCCCACACGTGCCGTGGAACCATCAACCTGTCCACCGCGCACATTG
ACACGGAGGACTCTTGTGGTATCTTGCTGACCAGTGGGGCCAGGAGCTACCACCTCAAGGCCAGCTCAGAGGTGGACCGGCAGCAGTGGA
TCACCGCCCTGGAGCTGGCCAAGGCCAAGGCTGTCCGCGTGATGAACACTCATTCAGGACACTGGCCTGAGACTGTCTGCAGTTGCACCG
CAGATCCTCCTGCCCGGCTGGCCCGACCCACCAGACCTCCCCACAGTGGATCCTATCTCATCCTCATTGACCTCTGCTCCAGCCCCTATG
CTGTCCGCAGTTTCTTGCCTCCCGATTGTCCCTGCACTGACCACTGTGTGCTCAGCGTGAAGGCTGCATAGAAGTGTGTACGGCTTGAGG

>61751_61751_2_OSBP2-MRPL43_OSBP2_chr22_31137356_ENST00000332585_MRPL43_chr10_102743574_ENST00000370242_length(amino acids)=365AA_BP=301
MPPAPTGRSAARGSAGSMGKAAAPSRGGGCGGRSRGLSSLFTVVPCLSCHTAAPGMSASTSGSGPEPKPQPQPVPEPERGPLSEQVSEAV
SEAVPRSEPVSETTSEPEPGAGQPSELLQGSRPGSESSSGVGAGPFTKAASEPLSRAVGSATFLRPESGSLPALKPLPLLRPGQAKTPLG
VPMSGTGTTSSAPLALLPLDSFEGWLLKWTNYLKGYQRRWFVLGNGLLSYYRNQGEMAHTCRGTINLSTAHIDTEDSCGILLTSGARSYH
LKASSEVDRQQWITALELAKAKAVRVMNTHSGHWPETVCSCTADPPARLARPTRPPHSGSYLILIDLCSSPYAVRSFLPPDCPCTDHCVL

--------------------------------------------------------------
>61751_61751_3_OSBP2-MRPL43_OSBP2_chr22_31137356_ENST00000382310_MRPL43_chr10_102743574_ENST00000342071_length(transcript)=1119nt_BP=889nt
ACTGGCCGCTCGGCCGCGCGCGGGTCGGCCGGCTCTATGGGGAAAGCGGCGGCTCCGAGCCGAGGCGGCGGCTGTGGCGGCCGCTCCCGC
GGGCTCTCGTCGCTGTTCACGGTTGTCCCCTGCCTGTCGTGCCACACGGCGGCGCCGGGCATGAGCGCTTCCACGTCCGGCTCCGGGCCG
GAGCCCAAGCCCCAGCCCCAGCCCGTGCCCGAACCGGAGCGGGGACCGCTGTCAGAACAGGTGTCGGAGGCAGTTTCGGAGGCAGTGCCA
AGATCGGAACCTGTGTCCGAGACGACGTCTGAGCCGGAGCCAGGGGCTGGGCAGCCATCGGAACTGCTGCAGGGGTCGCGGCCGGGGTCA
GAGTCAAGCTCAGGTGTAGGGGCTGGGCCCTTCACTAAGGCCGCATCGGAGCCGCTCTCCCGGGCGGTGGGGAGCGCGACCTTTCTCAGA
CCCGAGTCAGGATCGCTGCCAGCGTTAAAGCCCCTGCCTCTTCTGCGACCAGGACAGGCGAAGACTCCTCTTGGGGTTCCAATGTCGGGG
ACTGGCACGACCTCCAGTGCCCCACTGGCCTTACTGCCTCTGGACAGCTTCGAGGGCTGGCTTCTCAAGTGGACCAACTATCTGAAGGGC
TACCAGCGCCGCTGGTTCGTGCTGGGCAATGGTTTGCTCTCTTACTACAGAAATCAGGGTGAAATGGCCCACACGTGCCGTGGAACCATC
AACCTGTCCACCGCGCACATTGACACGGAGGACTCTTGTGGTATCTTGCTGACCAGTGGGGCCAGGAGCTACCACCTCAAGGCCAGCTCA
GAGGTGGACCGGCAGCAGTGGATCACCGCCCTGGAGCTGGCCAAGGCCAAGGCTGTCCGCGTGATGAACACTCATTCAGGACACTGGCCT
GAGACTGTCTGCAGTTGCACCGCAGATCCTCCTGCCCGGCTGGCCCGACCCAATATCAGTTCAGTCATCCGATCTTCCTTGGGGAAATAC
CCATTACCGTCCTGAACCCTTGTCATCCACTACTTGGCTATAAGCTCCAGAAGTGACAAGACACTTCACATCTTAAATATGTTTCCTAGT

>61751_61751_3_OSBP2-MRPL43_OSBP2_chr22_31137356_ENST00000382310_MRPL43_chr10_102743574_ENST00000342071_length(amino acids)=322AA_BP=284
MGKAAAPSRGGGCGGRSRGLSSLFTVVPCLSCHTAAPGMSASTSGSGPEPKPQPQPVPEPERGPLSEQVSEAVSEAVPRSEPVSETTSEP
EPGAGQPSELLQGSRPGSESSSGVGAGPFTKAASEPLSRAVGSATFLRPESGSLPALKPLPLLRPGQAKTPLGVPMSGTGTTSSAPLALL
PLDSFEGWLLKWTNYLKGYQRRWFVLGNGLLSYYRNQGEMAHTCRGTINLSTAHIDTEDSCGILLTSGARSYHLKASSEVDRQQWITALE

--------------------------------------------------------------
>61751_61751_4_OSBP2-MRPL43_OSBP2_chr22_31137356_ENST00000382310_MRPL43_chr10_102743574_ENST00000370242_length(transcript)=1127nt_BP=889nt
ACTGGCCGCTCGGCCGCGCGCGGGTCGGCCGGCTCTATGGGGAAAGCGGCGGCTCCGAGCCGAGGCGGCGGCTGTGGCGGCCGCTCCCGC
GGGCTCTCGTCGCTGTTCACGGTTGTCCCCTGCCTGTCGTGCCACACGGCGGCGCCGGGCATGAGCGCTTCCACGTCCGGCTCCGGGCCG
GAGCCCAAGCCCCAGCCCCAGCCCGTGCCCGAACCGGAGCGGGGACCGCTGTCAGAACAGGTGTCGGAGGCAGTTTCGGAGGCAGTGCCA
AGATCGGAACCTGTGTCCGAGACGACGTCTGAGCCGGAGCCAGGGGCTGGGCAGCCATCGGAACTGCTGCAGGGGTCGCGGCCGGGGTCA
GAGTCAAGCTCAGGTGTAGGGGCTGGGCCCTTCACTAAGGCCGCATCGGAGCCGCTCTCCCGGGCGGTGGGGAGCGCGACCTTTCTCAGA
CCCGAGTCAGGATCGCTGCCAGCGTTAAAGCCCCTGCCTCTTCTGCGACCAGGACAGGCGAAGACTCCTCTTGGGGTTCCAATGTCGGGG
ACTGGCACGACCTCCAGTGCCCCACTGGCCTTACTGCCTCTGGACAGCTTCGAGGGCTGGCTTCTCAAGTGGACCAACTATCTGAAGGGC
TACCAGCGCCGCTGGTTCGTGCTGGGCAATGGTTTGCTCTCTTACTACAGAAATCAGGGTGAAATGGCCCACACGTGCCGTGGAACCATC
AACCTGTCCACCGCGCACATTGACACGGAGGACTCTTGTGGTATCTTGCTGACCAGTGGGGCCAGGAGCTACCACCTCAAGGCCAGCTCA
GAGGTGGACCGGCAGCAGTGGATCACCGCCCTGGAGCTGGCCAAGGCCAAGGCTGTCCGCGTGATGAACACTCATTCAGGACACTGGCCT
GAGACTGTCTGCAGTTGCACCGCAGATCCTCCTGCCCGGCTGGCCCGACCCACCAGACCTCCCCACAGTGGATCCTATCTCATCCTCATT
GACCTCTGCTCCAGCCCCTATGCTGTCCGCAGTTTCTTGCCTCCCGATTGTCCCTGCACTGACCACTGTGTGCTCAGCGTGAAGGCTGCA

>61751_61751_4_OSBP2-MRPL43_OSBP2_chr22_31137356_ENST00000382310_MRPL43_chr10_102743574_ENST00000370242_length(amino acids)=348AA_BP=284
MGKAAAPSRGGGCGGRSRGLSSLFTVVPCLSCHTAAPGMSASTSGSGPEPKPQPQPVPEPERGPLSEQVSEAVSEAVPRSEPVSETTSEP
EPGAGQPSELLQGSRPGSESSSGVGAGPFTKAASEPLSRAVGSATFLRPESGSLPALKPLPLLRPGQAKTPLGVPMSGTGTTSSAPLALL
PLDSFEGWLLKWTNYLKGYQRRWFVLGNGLLSYYRNQGEMAHTCRGTINLSTAHIDTEDSCGILLTSGARSYHLKASSEVDRQQWITALE

--------------------------------------------------------------
>61751_61751_5_OSBP2-MRPL43_OSBP2_chr22_31137356_ENST00000403222_MRPL43_chr10_102743574_ENST00000342071_length(transcript)=867nt_BP=637nt
CATGGTGAAACCCCGTTTCTACTAAAAATACAAAATTTAGCTGGGCATGGTGCGGGCCGTGGAATTCCAGCTACTAGGGAGGCCAAGGCA
GGAGAATCGCTTGAACCTGGGAAGCGGAGGCTGCAGTGAACCAAGATCACGCCACTGCATTCCAGCCTGGGCTACCGAGTGAGACTCAGT
CTCAAAAAGGAAAAAAAAAAAAAGCGGAAAAAAAAATTCGCTGATGTTTTAACCATTCTGGGGTCACAGCCTCCTTTGTTATGGACCTAC
TCTGGAAAAATGCACAGACAGAGAACCCGAACGATGTCGTCACTGGCAGCGAAGCGCCTTGGCATGAACCGTAGGCCAGCTGGCTCAGGA
GGTGGAGGCGGTGAGGCGGCCACTTGGGGCCACCGCTTCTGGCGGCCGCAGGAGCGACCCACAGACAGAAATCAGGGTGAAATGGCCCAC
ACGTGCCGTGGAACCATCAACCTGTCCACCGCGCACATTGACACGGAGGACTCTTGTGGTATCTTGCTGACCAGTGGGGCCAGGAGCTAC
CACCTCAAGGCCAGCTCAGAGGTGGACCGGCAGCAGTGGATCACCGCCCTGGAGCTGGCCAAGGCCAAGGCTGTCCGCGTGATGAACACT
CATTCAGGACACTGGCCTGAGACTGTCTGCAGTTGCACCGCAGATCCTCCTGCCCGGCTGGCCCGACCCAATATCAGTTCAGTCATCCGA
TCTTCCTTGGGGAAATACCCATTACCGTCCTGAACCCTTGTCATCCACTACTTGGCTATAAGCTCCAGAAGTGACAAGACACTTCACATC

>61751_61751_5_OSBP2-MRPL43_OSBP2_chr22_31137356_ENST00000403222_MRPL43_chr10_102743574_ENST00000342071_length(amino acids)=202AA_BP=1
MHSSLGYRVRLSLKKEKKKKRKKKFADVLTILGSQPPLLWTYSGKMHRQRTRTMSSLAAKRLGMNRRPAGSGGGGGEAATWGHRFWRPQE
RPTDRNQGEMAHTCRGTINLSTAHIDTEDSCGILLTSGARSYHLKASSEVDRQQWITALELAKAKAVRVMNTHSGHWPETVCSCTADPPA

--------------------------------------------------------------
>61751_61751_6_OSBP2-MRPL43_OSBP2_chr22_31137356_ENST00000403222_MRPL43_chr10_102743574_ENST00000370242_length(transcript)=875nt_BP=637nt
CATGGTGAAACCCCGTTTCTACTAAAAATACAAAATTTAGCTGGGCATGGTGCGGGCCGTGGAATTCCAGCTACTAGGGAGGCCAAGGCA
GGAGAATCGCTTGAACCTGGGAAGCGGAGGCTGCAGTGAACCAAGATCACGCCACTGCATTCCAGCCTGGGCTACCGAGTGAGACTCAGT
CTCAAAAAGGAAAAAAAAAAAAAGCGGAAAAAAAAATTCGCTGATGTTTTAACCATTCTGGGGTCACAGCCTCCTTTGTTATGGACCTAC
TCTGGAAAAATGCACAGACAGAGAACCCGAACGATGTCGTCACTGGCAGCGAAGCGCCTTGGCATGAACCGTAGGCCAGCTGGCTCAGGA
GGTGGAGGCGGTGAGGCGGCCACTTGGGGCCACCGCTTCTGGCGGCCGCAGGAGCGACCCACAGACAGAAATCAGGGTGAAATGGCCCAC
ACGTGCCGTGGAACCATCAACCTGTCCACCGCGCACATTGACACGGAGGACTCTTGTGGTATCTTGCTGACCAGTGGGGCCAGGAGCTAC
CACCTCAAGGCCAGCTCAGAGGTGGACCGGCAGCAGTGGATCACCGCCCTGGAGCTGGCCAAGGCCAAGGCTGTCCGCGTGATGAACACT
CATTCAGGACACTGGCCTGAGACTGTCTGCAGTTGCACCGCAGATCCTCCTGCCCGGCTGGCCCGACCCACCAGACCTCCCCACAGTGGA
TCCTATCTCATCCTCATTGACCTCTGCTCCAGCCCCTATGCTGTCCGCAGTTTCTTGCCTCCCGATTGTCCCTGCACTGACCACTGTGTG

>61751_61751_6_OSBP2-MRPL43_OSBP2_chr22_31137356_ENST00000403222_MRPL43_chr10_102743574_ENST00000370242_length(amino acids)=228AA_BP=1
MHSSLGYRVRLSLKKEKKKKRKKKFADVLTILGSQPPLLWTYSGKMHRQRTRTMSSLAAKRLGMNRRPAGSGGGGGEAATWGHRFWRPQE
RPTDRNQGEMAHTCRGTINLSTAHIDTEDSCGILLTSGARSYHLKASSEVDRQQWITALELAKAKAVRVMNTHSGHWPETVCSCTADPPA

--------------------------------------------------------------
>61751_61751_7_OSBP2-MRPL43_OSBP2_chr22_31137356_ENST00000407373_MRPL43_chr10_102743574_ENST00000342071_length(transcript)=708nt_BP=478nt
AACCTCTGCGGAAGCCTCACAGACTGCCAGCCTACCCAGGGATCCCGGGAGGTCCAAGTTCAGAATCCCACTTTGAGATGTTTCTTGTAC
TAAAACGCTTGGTTTACAAAAAGTCTTCCCCTATTTGTTTAGAGAACCCGAACGATGTCGTCACTGGCAGCGAAGCGCCTTGGCATGAAC
CGTAGGCCAGCTGGCTCAGGAGGTGGAGGCGGTGAGGCGGCCACTTGGGGCCACCGCTTCTGGCGGCCGCAGGAGCGACCCACAGACAGA
AATCAGGGTGAAATGGCCCACACGTGCCGTGGAACCATCAACCTGTCCACCGCGCACATTGACACGGAGGACTCTTGTGGTATCTTGCTG
ACCAGTGGGGCCAGGAGCTACCACCTCAAGGCCAGCTCAGAGGTGGACCGGCAGCAGTGGATCACCGCCCTGGAGCTGGCCAAGGCCAAG
GCTGTCCGCGTGATGAACACTCATTCAGGACACTGGCCTGAGACTGTCTGCAGTTGCACCGCAGATCCTCCTGCCCGGCTGGCCCGACCC
AATATCAGTTCAGTCATCCGATCTTCCTTGGGGAAATACCCATTACCGTCCTGAACCCTTGTCATCCACTACTTGGCTATAAGCTCCAGA

>61751_61751_7_OSBP2-MRPL43_OSBP2_chr22_31137356_ENST00000407373_MRPL43_chr10_102743574_ENST00000342071_length(amino acids)=149AA_BP=111
MSSLAAKRLGMNRRPAGSGGGGGEAATWGHRFWRPQERPTDRNQGEMAHTCRGTINLSTAHIDTEDSCGILLTSGARSYHLKASSEVDRQ

--------------------------------------------------------------
>61751_61751_8_OSBP2-MRPL43_OSBP2_chr22_31137356_ENST00000407373_MRPL43_chr10_102743574_ENST00000370242_length(transcript)=716nt_BP=478nt
AACCTCTGCGGAAGCCTCACAGACTGCCAGCCTACCCAGGGATCCCGGGAGGTCCAAGTTCAGAATCCCACTTTGAGATGTTTCTTGTAC
TAAAACGCTTGGTTTACAAAAAGTCTTCCCCTATTTGTTTAGAGAACCCGAACGATGTCGTCACTGGCAGCGAAGCGCCTTGGCATGAAC
CGTAGGCCAGCTGGCTCAGGAGGTGGAGGCGGTGAGGCGGCCACTTGGGGCCACCGCTTCTGGCGGCCGCAGGAGCGACCCACAGACAGA
AATCAGGGTGAAATGGCCCACACGTGCCGTGGAACCATCAACCTGTCCACCGCGCACATTGACACGGAGGACTCTTGTGGTATCTTGCTG
ACCAGTGGGGCCAGGAGCTACCACCTCAAGGCCAGCTCAGAGGTGGACCGGCAGCAGTGGATCACCGCCCTGGAGCTGGCCAAGGCCAAG
GCTGTCCGCGTGATGAACACTCATTCAGGACACTGGCCTGAGACTGTCTGCAGTTGCACCGCAGATCCTCCTGCCCGGCTGGCCCGACCC
ACCAGACCTCCCCACAGTGGATCCTATCTCATCCTCATTGACCTCTGCTCCAGCCCCTATGCTGTCCGCAGTTTCTTGCCTCCCGATTGT

>61751_61751_8_OSBP2-MRPL43_OSBP2_chr22_31137356_ENST00000407373_MRPL43_chr10_102743574_ENST00000370242_length(amino acids)=175AA_BP=111
MSSLAAKRLGMNRRPAGSGGGGGEAATWGHRFWRPQERPTDRNQGEMAHTCRGTINLSTAHIDTEDSCGILLTSGARSYHLKASSEVDRQ

--------------------------------------------------------------
>61751_61751_9_OSBP2-MRPL43_OSBP2_chr22_31137356_ENST00000446658_MRPL43_chr10_102743574_ENST00000342071_length(transcript)=1104nt_BP=874nt
GCGCGCGGGTCGGCCGGCTCTATGGGGAAAGCGGCGGCTCCGAGCCGAGGCGGCGGCTGTGGCGGCCGCTCCCGCGGGCTCTCGTCGCTG
TTCACGGTTGTCCCCTGCCTGTCGTGCCACACGGCGGCGCCGGGCATGAGCGCTTCCACGTCCGGCTCCGGGCCGGAGCCCAAGCCCCAG
CCCCAGCCCGTGCCCGAACCGGAGCGGGGACCGCTGTCAGAACAGGTGTCGGAGGCAGTTTCGGAGGCAGTGCCAAGATCGGAACCTGTG
TCCGAGACGACGTCTGAGCCGGAGCCAGGGGCTGGGCAGCCATCGGAACTGCTGCAGGGGTCGCGGCCGGGGTCAGAGTCAAGCTCAGGT
GTAGGGGCTGGGCCCTTCACTAAGGCCGCATCGGAGCCGCTCTCCCGGGCGGTGGGGAGCGCGACCTTTCTCAGACCCGAGTCAGGATCG
CTGCCAGCGTTAAAGCCCCTGCCTCTTCTGCGACCAGGACAGGCGAAGACTCCTCTTGGGGTTCCAATGTCGGGGACTGGCACGACCTCC
AGTGCCCCACTGGCCTTACTGCCTCTGGACAGCTTCGAGGGCTGGCTTCTCAAGTGGACCAACTATCTGAAGGGCTACCAGCGCCGCTGG
TTCGTGCTGGGCAATGGTTTGCTCTCTTACTACAGAAATCAGGGTGAAATGGCCCACACGTGCCGTGGAACCATCAACCTGTCCACCGCG
CACATTGACACGGAGGACTCTTGTGGTATCTTGCTGACCAGTGGGGCCAGGAGCTACCACCTCAAGGCCAGCTCAGAGGTGGACCGGCAG
CAGTGGATCACCGCCCTGGAGCTGGCCAAGGCCAAGGCTGTCCGCGTGATGAACACTCATTCAGGACACTGGCCTGAGACTGTCTGCAGT
TGCACCGCAGATCCTCCTGCCCGGCTGGCCCGACCCAATATCAGTTCAGTCATCCGATCTTCCTTGGGGAAATACCCATTACCGTCCTGA
ACCCTTGTCATCCACTACTTGGCTATAAGCTCCAGAAGTGACAAGACACTTCACATCTTAAATATGTTTCCTAGTTTATAATTCATTTGG

>61751_61751_9_OSBP2-MRPL43_OSBP2_chr22_31137356_ENST00000446658_MRPL43_chr10_102743574_ENST00000342071_length(amino acids)=322AA_BP=284
MGKAAAPSRGGGCGGRSRGLSSLFTVVPCLSCHTAAPGMSASTSGSGPEPKPQPQPVPEPERGPLSEQVSEAVSEAVPRSEPVSETTSEP
EPGAGQPSELLQGSRPGSESSSGVGAGPFTKAASEPLSRAVGSATFLRPESGSLPALKPLPLLRPGQAKTPLGVPMSGTGTTSSAPLALL
PLDSFEGWLLKWTNYLKGYQRRWFVLGNGLLSYYRNQGEMAHTCRGTINLSTAHIDTEDSCGILLTSGARSYHLKASSEVDRQQWITALE

--------------------------------------------------------------
>61751_61751_10_OSBP2-MRPL43_OSBP2_chr22_31137356_ENST00000446658_MRPL43_chr10_102743574_ENST00000370242_length(transcript)=1112nt_BP=874nt
GCGCGCGGGTCGGCCGGCTCTATGGGGAAAGCGGCGGCTCCGAGCCGAGGCGGCGGCTGTGGCGGCCGCTCCCGCGGGCTCTCGTCGCTG
TTCACGGTTGTCCCCTGCCTGTCGTGCCACACGGCGGCGCCGGGCATGAGCGCTTCCACGTCCGGCTCCGGGCCGGAGCCCAAGCCCCAG
CCCCAGCCCGTGCCCGAACCGGAGCGGGGACCGCTGTCAGAACAGGTGTCGGAGGCAGTTTCGGAGGCAGTGCCAAGATCGGAACCTGTG
TCCGAGACGACGTCTGAGCCGGAGCCAGGGGCTGGGCAGCCATCGGAACTGCTGCAGGGGTCGCGGCCGGGGTCAGAGTCAAGCTCAGGT
GTAGGGGCTGGGCCCTTCACTAAGGCCGCATCGGAGCCGCTCTCCCGGGCGGTGGGGAGCGCGACCTTTCTCAGACCCGAGTCAGGATCG
CTGCCAGCGTTAAAGCCCCTGCCTCTTCTGCGACCAGGACAGGCGAAGACTCCTCTTGGGGTTCCAATGTCGGGGACTGGCACGACCTCC
AGTGCCCCACTGGCCTTACTGCCTCTGGACAGCTTCGAGGGCTGGCTTCTCAAGTGGACCAACTATCTGAAGGGCTACCAGCGCCGCTGG
TTCGTGCTGGGCAATGGTTTGCTCTCTTACTACAGAAATCAGGGTGAAATGGCCCACACGTGCCGTGGAACCATCAACCTGTCCACCGCG
CACATTGACACGGAGGACTCTTGTGGTATCTTGCTGACCAGTGGGGCCAGGAGCTACCACCTCAAGGCCAGCTCAGAGGTGGACCGGCAG
CAGTGGATCACCGCCCTGGAGCTGGCCAAGGCCAAGGCTGTCCGCGTGATGAACACTCATTCAGGACACTGGCCTGAGACTGTCTGCAGT
TGCACCGCAGATCCTCCTGCCCGGCTGGCCCGACCCACCAGACCTCCCCACAGTGGATCCTATCTCATCCTCATTGACCTCTGCTCCAGC
CCCTATGCTGTCCGCAGTTTCTTGCCTCCCGATTGTCCCTGCACTGACCACTGTGTGCTCAGCGTGAAGGCTGCATAGAAGTGTGTACGG

>61751_61751_10_OSBP2-MRPL43_OSBP2_chr22_31137356_ENST00000446658_MRPL43_chr10_102743574_ENST00000370242_length(amino acids)=348AA_BP=284
MGKAAAPSRGGGCGGRSRGLSSLFTVVPCLSCHTAAPGMSASTSGSGPEPKPQPQPVPEPERGPLSEQVSEAVSEAVPRSEPVSETTSEP
EPGAGQPSELLQGSRPGSESSSGVGAGPFTKAASEPLSRAVGSATFLRPESGSLPALKPLPLLRPGQAKTPLGVPMSGTGTTSSAPLALL
PLDSFEGWLLKWTNYLKGYQRRWFVLGNGLLSYYRNQGEMAHTCRGTINLSTAHIDTEDSCGILLTSGARSYHLKASSEVDRQQWITALE

--------------------------------------------------------------

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Fusion Gene PPI Analysis for OSBP2-MRPL43


check button Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in

ChiPPI page.


check button Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160)
HgeneHgene's interactorsTgeneTgene's interactors


check button - Retained PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenStill interaction with


check button - Lost PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


check button - Retained PPIs, but lost function due to frame-shift fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


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Related Drugs for OSBP2-MRPL43


check button Drugs targeting genes involved in this fusion gene.
(DrugBank Version 5.1.8 2021-05-08)
PartnerGeneUniProtAccDrugBank IDDrug nameDrug activityDrug typeDrug status

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Related Diseases for OSBP2-MRPL43


check button Diseases associated with fusion partners.
(DisGeNet 4.0)
PartnerGeneDisease IDDisease name# pubmedsSource