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Center for Computational Systems Medicine
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Fusion Gene Summary

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Fusion Gene ORF analysis

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Fusion Genomic Features

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Fusion Protein Features

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Fusion Gene Sequence

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Fusion Gene PPI analysis

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Related Drugs

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Related Diseases

Fusion gene:OTUB1-IRF7 (FusionGDB2 ID:61950)

Fusion Gene Summary for OTUB1-IRF7

check button Fusion gene summary
Fusion gene informationFusion gene name: OTUB1-IRF7
Fusion gene ID: 61950
HgeneTgene
Gene symbol

OTUB1

IRF7

Gene ID

55611

3665

Gene nameOTU deubiquitinase, ubiquitin aldehyde binding 1interferon regulatory factor 7
SynonymsHSPC263|OTB1|OTU1IMD39|IRF-7|IRF-7H|IRF7A|IRF7B|IRF7C|IRF7H
Cytomap

11q13.1

11p15.5

Type of geneprotein-codingprotein-coding
Descriptionubiquitin thioesterase OTUB1OTU domain, ubiquitin aldehyde binding 1OTU domain-containing ubiquitin aldehyde-binding protein 1OTU-domain Ubal-binding 1deubiquitinating enzyme OTUB1otubain-1ubiquitin-specific protease otubain 1ubiquitin-specific-prointerferon regulatory factor 7interferon regulatory factor 7G isoforminterferon regulatory factor-7H
Modification date2020031320200313
UniProtAcc.

Q92985

Ensembl transtripts involved in fusion geneENST00000422031, ENST00000428192, 
ENST00000535715, ENST00000538426, 
ENST00000543004, ENST00000543988, 
ENST00000536443, ENST00000541478, 
ENST00000330243, ENST00000348655, 
ENST00000397562, ENST00000397566, 
ENST00000525445, ENST00000397570, 
ENST00000397574, 
Fusion gene scores* DoF score10 X 8 X 7=5602 X 2 X 2=8
# samples 102
** MAII scorelog2(10/560*10)=-2.48542682717024
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0		log2(2/8*10)=1.32192809488736
Context

PubMed: OTUB1 [Title/Abstract] AND IRF7 [Title/Abstract] AND fusion [Title/Abstract]

Most frequent breakpointOTUB1(63764120)-IRF7(612800), # samples:1
Anticipated loss of major functional domain due to fusion event.OTUB1-IRF7 seems lost the major protein functional domain in Hgene partner, which is a essential gene due to the frame-shifted ORF.
OTUB1-IRF7 seems lost the major protein functional domain in Tgene partner, which is a transcription factor due to the frame-shifted ORF.
* DoF score (Degree of Frequency) = # partners X # break points X # cancer types
** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)

check button Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez
PartnerGeneGO IDGO termPubMed ID
HgeneOTUB1

GO:0006974

cellular response to DNA damage stimulus

20725033

HgeneOTUB1

GO:0071108

protein K48-linked deubiquitination

18954305|19211026|23827681

HgeneOTUB1

GO:1901315

negative regulation of histone H2A K63-linked ubiquitination

20725033

TgeneIRF7

GO:0002819

regulation of adaptive immune response

17404045

TgeneIRF7

GO:0032727

positive regulation of interferon-alpha production

16127453

TgeneIRF7

GO:0045944

positive regulation of transcription by RNA polymerase II

16127453|17404045

TgeneIRF7

GO:0051607

defense response to virus

21478870


check buttonFusion gene breakpoints across OTUB1 (5'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check buttonFusion gene breakpoints across IRF7 (3'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check button Fusion gene information from two resources (ChiTars 5.0 and ChimerDB 4.0)
* All genome coordinats were lifted-over on hg19.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
SourceDiseaseSampleHgeneHchrHbpHstrandTgeneTchrTbpTstrand
ChimerDB4Non-Cancer61NOTUB1chr11

63764120

+IRF7chr11

612800

-


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Fusion Gene ORF analysis for OTUB1-IRF7

check button Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
ORFHenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrand
Frame-shiftENST00000422031ENST00000330243OTUB1chr11

63764120

+IRF7chr11

612800

-
Frame-shiftENST00000422031ENST00000348655OTUB1chr11

63764120

+IRF7chr11

612800

-
Frame-shiftENST00000422031ENST00000397562OTUB1chr11

63764120

+IRF7chr11

612800

-
Frame-shiftENST00000422031ENST00000397566OTUB1chr11

63764120

+IRF7chr11

612800

-
Frame-shiftENST00000422031ENST00000525445OTUB1chr11

63764120

+IRF7chr11

612800

-
Frame-shiftENST00000428192ENST00000330243OTUB1chr11

63764120

+IRF7chr11

612800

-
Frame-shiftENST00000428192ENST00000348655OTUB1chr11

63764120

+IRF7chr11

612800

-
Frame-shiftENST00000428192ENST00000397562OTUB1chr11

63764120

+IRF7chr11

612800

-
Frame-shiftENST00000428192ENST00000397566OTUB1chr11

63764120

+IRF7chr11

612800

-
Frame-shiftENST00000428192ENST00000525445OTUB1chr11

63764120

+IRF7chr11

612800

-
Frame-shiftENST00000535715ENST00000330243OTUB1chr11

63764120

+IRF7chr11

612800

-
Frame-shiftENST00000535715ENST00000348655OTUB1chr11

63764120

+IRF7chr11

612800

-
Frame-shiftENST00000535715ENST00000397562OTUB1chr11

63764120

+IRF7chr11

612800

-
Frame-shiftENST00000535715ENST00000397566OTUB1chr11

63764120

+IRF7chr11

612800

-
Frame-shiftENST00000535715ENST00000525445OTUB1chr11

63764120

+IRF7chr11

612800

-
Frame-shiftENST00000538426ENST00000330243OTUB1chr11

63764120

+IRF7chr11

612800

-
Frame-shiftENST00000538426ENST00000348655OTUB1chr11

63764120

+IRF7chr11

612800

-
Frame-shiftENST00000538426ENST00000397562OTUB1chr11

63764120

+IRF7chr11

612800

-
Frame-shiftENST00000538426ENST00000397566OTUB1chr11

63764120

+IRF7chr11

612800

-
Frame-shiftENST00000538426ENST00000525445OTUB1chr11

63764120

+IRF7chr11

612800

-
Frame-shiftENST00000543004ENST00000330243OTUB1chr11

63764120

+IRF7chr11

612800

-
Frame-shiftENST00000543004ENST00000348655OTUB1chr11

63764120

+IRF7chr11

612800

-
Frame-shiftENST00000543004ENST00000397562OTUB1chr11

63764120

+IRF7chr11

612800

-
Frame-shiftENST00000543004ENST00000397566OTUB1chr11

63764120

+IRF7chr11

612800

-
Frame-shiftENST00000543004ENST00000525445OTUB1chr11

63764120

+IRF7chr11

612800

-
Frame-shiftENST00000543988ENST00000330243OTUB1chr11

63764120

+IRF7chr11

612800

-
Frame-shiftENST00000543988ENST00000348655OTUB1chr11

63764120

+IRF7chr11

612800

-
Frame-shiftENST00000543988ENST00000397562OTUB1chr11

63764120

+IRF7chr11

612800

-
Frame-shiftENST00000543988ENST00000397566OTUB1chr11

63764120

+IRF7chr11

612800

-
Frame-shiftENST00000543988ENST00000525445OTUB1chr11

63764120

+IRF7chr11

612800

-
In-frameENST00000422031ENST00000397570OTUB1chr11

63764120

+IRF7chr11

612800

-
In-frameENST00000422031ENST00000397574OTUB1chr11

63764120

+IRF7chr11

612800

-
In-frameENST00000428192ENST00000397570OTUB1chr11

63764120

+IRF7chr11

612800

-
In-frameENST00000428192ENST00000397574OTUB1chr11

63764120

+IRF7chr11

612800

-
In-frameENST00000535715ENST00000397570OTUB1chr11

63764120

+IRF7chr11

612800

-
In-frameENST00000535715ENST00000397574OTUB1chr11

63764120

+IRF7chr11

612800

-
In-frameENST00000538426ENST00000397570OTUB1chr11

63764120

+IRF7chr11

612800

-
In-frameENST00000538426ENST00000397574OTUB1chr11

63764120

+IRF7chr11

612800

-
In-frameENST00000543004ENST00000397570OTUB1chr11

63764120

+IRF7chr11

612800

-
In-frameENST00000543004ENST00000397574OTUB1chr11

63764120

+IRF7chr11

612800

-
In-frameENST00000543988ENST00000397570OTUB1chr11

63764120

+IRF7chr11

612800

-
In-frameENST00000543988ENST00000397574OTUB1chr11

63764120

+IRF7chr11

612800

-
intron-3CDSENST00000536443ENST00000330243OTUB1chr11

63764120

+IRF7chr11

612800

-
intron-3CDSENST00000536443ENST00000348655OTUB1chr11

63764120

+IRF7chr11

612800

-
intron-3CDSENST00000536443ENST00000397562OTUB1chr11

63764120

+IRF7chr11

612800

-
intron-3CDSENST00000536443ENST00000397566OTUB1chr11

63764120

+IRF7chr11

612800

-
intron-3CDSENST00000536443ENST00000397570OTUB1chr11

63764120

+IRF7chr11

612800

-
intron-3CDSENST00000536443ENST00000397574OTUB1chr11

63764120

+IRF7chr11

612800

-
intron-3CDSENST00000536443ENST00000525445OTUB1chr11

63764120

+IRF7chr11

612800

-
intron-3CDSENST00000541478ENST00000330243OTUB1chr11

63764120

+IRF7chr11

612800

-
intron-3CDSENST00000541478ENST00000348655OTUB1chr11

63764120

+IRF7chr11

612800

-
intron-3CDSENST00000541478ENST00000397562OTUB1chr11

63764120

+IRF7chr11

612800

-
intron-3CDSENST00000541478ENST00000397566OTUB1chr11

63764120

+IRF7chr11

612800

-
intron-3CDSENST00000541478ENST00000397570OTUB1chr11

63764120

+IRF7chr11

612800

-
intron-3CDSENST00000541478ENST00000397574OTUB1chr11

63764120

+IRF7chr11

612800

-
intron-3CDSENST00000541478ENST00000525445OTUB1chr11

63764120

+IRF7chr11

612800

-

check buttonORFfinder result based on the fusion transcript sequence of in-frame fusion genes.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandSeq length
(transcript)		BP loci
(transcript)		Predicted start
(transcript)		Predicted stop
(transcript)		Seq length
(amino acids)
ENST00000535715OTUB1chr1163764120+ENST00000397570IRF7chr11612800-1036790410820136
ENST00000535715OTUB1chr1163764120+ENST00000397574IRF7chr11612800-1032790410820136
ENST00000422031OTUB1chr1163764120+ENST00000397570IRF7chr11612800-90766111691226
ENST00000422031OTUB1chr1163764120+ENST00000397574IRF7chr11612800-90366111691226
ENST00000428192OTUB1chr1163764120+ENST00000397570IRF7chr11612800-90766111691226
ENST00000428192OTUB1chr1163764120+ENST00000397574IRF7chr11612800-90366111691226
ENST00000538426OTUB1chr1163764120+ENST00000397570IRF7chr11612800-6283822412136
ENST00000538426OTUB1chr1163764120+ENST00000397574IRF7chr11612800-6243822412136
ENST00000543004OTUB1chr1163764120+ENST00000397570IRF7chr11612800-62237611406131
ENST00000543004OTUB1chr1163764120+ENST00000397574IRF7chr11612800-61837611406131
ENST00000543988OTUB1chr1163764120+ENST00000397570IRF7chr11612800-723477160507115
ENST00000543988OTUB1chr1163764120+ENST00000397574IRF7chr11612800-719477160507115

check buttonDeepORF prediction of the coding potential based on the fusion transcript sequence of in-frame fusion genes. DeepORF is a coding potential classifier based on convolutional neural network by comparing the real Ribo-seq data. If the no-coding score < 0.5 and coding score > 0.5, then the in-frame fusion transcript is predicted as being likely translated.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandNo-coding scoreCoding score
ENST00000535715ENST00000397570OTUB1chr1163764120+IRF7chr11612800-0.0089707080.99102926
ENST00000535715ENST00000397574OTUB1chr1163764120+IRF7chr11612800-0.0095103770.9904896
ENST00000422031ENST00000397570OTUB1chr1163764120+IRF7chr11612800-0.0052310720.994769
ENST00000422031ENST00000397574OTUB1chr1163764120+IRF7chr11612800-0.0056697010.9943303
ENST00000428192ENST00000397570OTUB1chr1163764120+IRF7chr11612800-0.0052310720.994769
ENST00000428192ENST00000397574OTUB1chr1163764120+IRF7chr11612800-0.0056697010.9943303
ENST00000538426ENST00000397570OTUB1chr1163764120+IRF7chr11612800-0.0044021290.9955979
ENST00000538426ENST00000397574OTUB1chr1163764120+IRF7chr11612800-0.0044320820.99556786
ENST00000543004ENST00000397570OTUB1chr1163764120+IRF7chr11612800-0.0017355110.9982645
ENST00000543004ENST00000397574OTUB1chr1163764120+IRF7chr11612800-0.0018948610.99810517
ENST00000543988ENST00000397570OTUB1chr1163764120+IRF7chr11612800-0.125601320.8743987
ENST00000543988ENST00000397574OTUB1chr1163764120+IRF7chr11612800-0.142988830.8570112

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Fusion Genomic Features for OTUB1-IRF7


check buttonFusionAI prediction of the potential fusion gene breakpoint based on the pre-mature RNA sequence context (+/- 5kb of individual partner genes, total 20kb length sequence). FusionAI is a fusion gene breakpoint classifier based on convolutional neural network by comparing the fusion positive and negative sequence context of ~ 20K fusion gene data. From here, we can have the relative potentency of the 20K genomic sequence how individual sequnce will be likely used as the gene fusion breakpoints.
HgeneHchrHbpHstrandTgeneTchrTbpTstrand1-pp (fusion gene breakpoint)

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions. We integrated a total of 44 different types of human genomic feature loci information across five big categories including virus integration sites, repeats, structural variants, chromatin states, and gene expression regulation. More details are in help page.
genomic feature

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions that are ovelapped with the top 1% feature importance score regions. More details are in help page.

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Fusion Protein Features for OTUB1-IRF7


check button Four levels of functional features of fusion genes
Go to FGviewer search page for the most frequent breakpoint (https://ccsmweb.uth.edu/FGviewer/chr11:63764120/chr11:612800)
- FGviewer provides the online visualization of the retention search of the protein functional features across DNA, RNA, protein, and pathological levels.
- How to search
1. Put your fusion gene symbol.
2. Press the tab key until there will be shown the breakpoint information filled.
4. Go down and press 'Search' tab twice.
4. Go down to have the hyperlink of the search result.
5. Click the hyperlink.
6. See the FGviewer result for your fusion gene.
FGviewer

check buttonMain function of each fusion partner protein. (from UniProt)
HgeneTgene
.IRF7

Q92985

FUNCTION: Transcriptional activator which is required for calcium-dependent dendritic growth and branching in cortical neurons. Recruits CREB-binding protein (CREBBP) to nuclear bodies. Component of the CREST-BRG1 complex, a multiprotein complex that regulates promoter activation by orchestrating a calcium-dependent release of a repressor complex and a recruitment of an activator complex. In resting neurons, transcription of the c-FOS promoter is inhibited by BRG1-dependent recruitment of a phospho-RB1-HDAC1 repressor complex. Upon calcium influx, RB1 is dephosphorylated by calcineurin, which leads to release of the repressor complex. At the same time, there is increased recruitment of CREBBP to the promoter by a CREST-dependent mechanism, which leads to transcriptional activation. The CREST-BRG1 complex also binds to the NR2B promoter, and activity-dependent induction of NR2B expression involves a release of HDAC1 and recruitment of CREBBP (By similarity). {ECO:0000250}.FUNCTION: Key transcriptional regulator of type I interferon (IFN)-dependent immune responses and plays a critical role in the innate immune response against DNA and RNA viruses. Regulates the transcription of type I IFN genes (IFN-alpha and IFN-beta) and IFN-stimulated genes (ISG) by binding to an interferon-stimulated response element (ISRE) in their promoters (PubMed:17574024, PubMed:32972995). Can efficiently activate both the IFN-beta (IFNB) and the IFN-alpha (IFNA) genes and mediate their induction via both the virus-activated, MyD88-independent pathway and the TLR-activated, MyD88-dependent pathway. Induces transcription of ubiquitin hydrolase USP25 mRNA in response to lipopolysaccharide (LPS) or viral infection in a type I IFN-dependent manner (By similarity). Required during both the early and late phases of the IFN gene induction but is more critical for the late than for the early phase. Exists in an inactive form in the cytoplasm of uninfected cells and following viral infection, double-stranded RNA (dsRNA), or toll-like receptor (TLR) signaling, becomes phosphorylated by IKBKE and TBK1 kinases. This induces a conformational change, leading to its dimerization and nuclear localization where along with other coactivators it can activate transcription of the type I IFN and ISG genes. Can also play a role in regulating adaptive immune responses by inducing PSMB9/LMP2 expression, either directly or through induction of IRF1. Binds to the Q promoter (Qp) of EBV nuclear antigen 1 a (EBNA1) and may play a role in the regulation of EBV latency. Can activate distinct gene expression programs in macrophages and regulate the anti-tumor properties of primary macrophages (By similarity) (PubMed:11073981, PubMed:12374802, PubMed:15361868, PubMed:17404045). {ECO:0000250|UniProtKB:P70434, ECO:0000269|PubMed:11073981, ECO:0000269|PubMed:12374802, ECO:0000269|PubMed:15361868, ECO:0000269|PubMed:17404045, ECO:0000269|PubMed:17574024, ECO:0000269|PubMed:32972995}.

check buttonRetention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at

download page


* Minus value of BPloci means that the break pointn is located before the CDS.
- In-frame and retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note

- In-frame and not-retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneOTUB1chr11:63764120chr11:612800ENST00000428192+5880_271112272.0DomainOTU
HgeneOTUB1chr11:63764120chr11:612800ENST00000538426+4780_271112272.0DomainOTU
HgeneOTUB1chr11:63764120chr11:612800ENST00000428192+58130_138112272.0RegionUbiquitin-conjugating enzyme E2 binding
HgeneOTUB1chr11:63764120chr11:612800ENST00000428192+58169_177112272.0RegionUbiquitin-conjugating enzyme E2 binding
HgeneOTUB1chr11:63764120chr11:612800ENST00000428192+58189_195112272.0RegionFree ubiquitin binding
HgeneOTUB1chr11:63764120chr11:612800ENST00000428192+58206_213112272.0RegionUbiquitin-conjugating enzyme E2 binding
HgeneOTUB1chr11:63764120chr11:612800ENST00000428192+58214_221112272.0RegionFree ubiquitin binding
HgeneOTUB1chr11:63764120chr11:612800ENST00000428192+58245_251112272.0RegionFree ubiquitin binding
HgeneOTUB1chr11:63764120chr11:612800ENST00000538426+47130_138112272.0RegionUbiquitin-conjugating enzyme E2 binding
HgeneOTUB1chr11:63764120chr11:612800ENST00000538426+47169_177112272.0RegionUbiquitin-conjugating enzyme E2 binding
HgeneOTUB1chr11:63764120chr11:612800ENST00000538426+47189_195112272.0RegionFree ubiquitin binding
HgeneOTUB1chr11:63764120chr11:612800ENST00000538426+47206_213112272.0RegionUbiquitin-conjugating enzyme E2 binding
HgeneOTUB1chr11:63764120chr11:612800ENST00000538426+47214_221112272.0RegionFree ubiquitin binding
HgeneOTUB1chr11:63764120chr11:612800ENST00000538426+47245_251112272.0RegionFree ubiquitin binding
TgeneIRF7chr11:63764120chr11:612800ENST0000033024381011_126465517.0DNA bindingIRF tryptophan pentad repeat
TgeneIRF7chr11:63764120chr11:612800ENST000003486557911_126423475.0DNA bindingIRF tryptophan pentad repeat
TgeneIRF7chr11:63764120chr11:612800ENST000003975667911_126465517.0DNA bindingIRF tryptophan pentad repeat
TgeneIRF7chr11:63764120chr11:612800ENST0000039757081011_126423475.0DNA bindingIRF tryptophan pentad repeat
TgeneIRF7chr11:63764120chr11:612800ENST0000039757491111_126452504.0DNA bindingIRF tryptophan pentad repeat


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Fusion Gene Sequence for OTUB1-IRF7


check button For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. To have fusion amino acid sequence, we ran ORFfinder and chose the longest ORF among the all predicted ones.
>61950_61950_1_OTUB1-IRF7_OTUB1_chr11_63764120_ENST00000422031_IRF7_chr11_612800_ENST00000397570_length(transcript)=907nt_BP=661nt
GCTGCTCCGCACTGCAGCTATGGTCGCATGCAGTGCCTGCCGAAGCCCGCAGCAGGAATGCTGCCTTCGGTGATTTTAATTTCACTTTTC
TACTTCTCTCAATAACAAAATCCGCGTTTCAAACTCCAGGGAAAAGAAAACGGAATTGGCTCCAGGAGGATCTGCAATCACCACCGGGAA
CTTTGGGAGGCTGGGAAGATGGAGCCAAACCAATGTGTGGGGTGGAGGGCTGTTGCCAAGGCGGGGCAACGAGGAGGGGCTCGCTTCCGG
GAGGACGGCAATTGGCAACCCGGAAGCGGTCGGTAGTGCGGCGCTGTTTAAAGATGGCGGCGGAGGAACCTCAGCAGCAGAAGCAGGAGC
CGCTGGGCAGCGACTCCGAAGGTGTTAACTGTCTGGCCTATGATGAAGCCATCATGGCTCAGCAGGACCGAATTCAGCAAGAGATTGCTG
TGCAGAACCCTCTGGTGTCAGAGCGGCTGGAGCTCTCGGTCCTATACAAGGAGTATGCTGAAGATGACAACATCTATCAACAGAAGATCA
AGGACCTCCACAAAAAGTACTCGTACATCCGCAAGACCAGGCCTGACGGCAACTGTTTCTATCGGGCTTTCGGATTCTCCCACTTGGAGG
CACTGCTGGATGACAGCAAGGAGTTGCAGCGCTGGAACCCTGGCTGTGCCGAGTGCACCTAGAGGGCACGCAGCGTGAGGGTGTGTCTTC
CCTGGATAGCAGCAGCCTCAGCCTCTGCCTGTCCAGCGCCAACAGCCTCTATGACGACATCGAGTGCTTCCTTATGGAGCTGGAGCAGCC
CGCCTAGAACCCAGTCTAATGAGAACTCCAGAAAGCTGGAGCAGCCCACCTAGAGCTGGCCGCGGCCGCCCAGTCTAATAAAAAGAACTC

>61950_61950_1_OTUB1-IRF7_OTUB1_chr11_63764120_ENST00000422031_IRF7_chr11_612800_ENST00000397570_length(amino acids)=226AA_BP=
MQLWSHAVPAEARSRNAAFGDFNFTFLLLSITKSAFQTPGKRKRNWLQEDLQSPPGTLGGWEDGAKPMCGVEGCCQGGATRRGSLPGGRQ
LATRKRSVVRRCLKMAAEEPQQQKQEPLGSDSEGVNCLAYDEAIMAQQDRIQQEIAVQNPLVSERLELSVLYKEYAEDDNIYQQKIKDLH

--------------------------------------------------------------
>61950_61950_2_OTUB1-IRF7_OTUB1_chr11_63764120_ENST00000422031_IRF7_chr11_612800_ENST00000397574_length(transcript)=903nt_BP=661nt
GCTGCTCCGCACTGCAGCTATGGTCGCATGCAGTGCCTGCCGAAGCCCGCAGCAGGAATGCTGCCTTCGGTGATTTTAATTTCACTTTTC
TACTTCTCTCAATAACAAAATCCGCGTTTCAAACTCCAGGGAAAAGAAAACGGAATTGGCTCCAGGAGGATCTGCAATCACCACCGGGAA
CTTTGGGAGGCTGGGAAGATGGAGCCAAACCAATGTGTGGGGTGGAGGGCTGTTGCCAAGGCGGGGCAACGAGGAGGGGCTCGCTTCCGG
GAGGACGGCAATTGGCAACCCGGAAGCGGTCGGTAGTGCGGCGCTGTTTAAAGATGGCGGCGGAGGAACCTCAGCAGCAGAAGCAGGAGC
CGCTGGGCAGCGACTCCGAAGGTGTTAACTGTCTGGCCTATGATGAAGCCATCATGGCTCAGCAGGACCGAATTCAGCAAGAGATTGCTG
TGCAGAACCCTCTGGTGTCAGAGCGGCTGGAGCTCTCGGTCCTATACAAGGAGTATGCTGAAGATGACAACATCTATCAACAGAAGATCA
AGGACCTCCACAAAAAGTACTCGTACATCCGCAAGACCAGGCCTGACGGCAACTGTTTCTATCGGGCTTTCGGATTCTCCCACTTGGAGG
CACTGCTGGATGACAGCAAGGAGTTGCAGCGCTGGAACCCTGGCTGTGCCGAGTGCACCTAGAGGGCACGCAGCGTGAGGGTGTGTCTTC
CCTGGATAGCAGCAGCCTCAGCCTCTGCCTGTCCAGCGCCAACAGCCTCTATGACGACATCGAGTGCTTCCTTATGGAGCTGGAGCAGCC
CGCCTAGAACCCAGTCTAATGAGAACTCCAGAAAGCTGGAGCAGCCCACCTAGAGCTGGCCGCGGCCGCCCAGTCTAATAAAAAGAACTC

>61950_61950_2_OTUB1-IRF7_OTUB1_chr11_63764120_ENST00000422031_IRF7_chr11_612800_ENST00000397574_length(amino acids)=226AA_BP=
MQLWSHAVPAEARSRNAAFGDFNFTFLLLSITKSAFQTPGKRKRNWLQEDLQSPPGTLGGWEDGAKPMCGVEGCCQGGATRRGSLPGGRQ
LATRKRSVVRRCLKMAAEEPQQQKQEPLGSDSEGVNCLAYDEAIMAQQDRIQQEIAVQNPLVSERLELSVLYKEYAEDDNIYQQKIKDLH

--------------------------------------------------------------
>61950_61950_3_OTUB1-IRF7_OTUB1_chr11_63764120_ENST00000428192_IRF7_chr11_612800_ENST00000397570_length(transcript)=907nt_BP=661nt
GCTGCTCCGCACTGCAGCTATGGTCGCATGCAGTGCCTGCCGAAGCCCGCAGCAGGAATGCTGCCTTCGGTGATTTTAATTTCACTTTTC
TACTTCTCTCAATAACAAAATCCGCGTTTCAAACTCCAGGGAAAAGAAAACGGAATTGGCTCCAGGAGGATCTGCAATCACCACCGGGAA
CTTTGGGAGGCTGGGAAGATGGAGCCAAACCAATGTGTGGGGTGGAGGGCTGTTGCCAAGGCGGGGCAACGAGGAGGGGCTCGCTTCCGG
GAGGACGGCAATTGGCAACCCGGAAGCGGTCGGTAGTGCGGCGCTGTTTAAAGATGGCGGCGGAGGAACCTCAGCAGCAGAAGCAGGAGC
CGCTGGGCAGCGACTCCGAAGGTGTTAACTGTCTGGCCTATGATGAAGCCATCATGGCTCAGCAGGACCGAATTCAGCAAGAGATTGCTG
TGCAGAACCCTCTGGTGTCAGAGCGGCTGGAGCTCTCGGTCCTATACAAGGAGTATGCTGAAGATGACAACATCTATCAACAGAAGATCA
AGGACCTCCACAAAAAGTACTCGTACATCCGCAAGACCAGGCCTGACGGCAACTGTTTCTATCGGGCTTTCGGATTCTCCCACTTGGAGG
CACTGCTGGATGACAGCAAGGAGTTGCAGCGCTGGAACCCTGGCTGTGCCGAGTGCACCTAGAGGGCACGCAGCGTGAGGGTGTGTCTTC
CCTGGATAGCAGCAGCCTCAGCCTCTGCCTGTCCAGCGCCAACAGCCTCTATGACGACATCGAGTGCTTCCTTATGGAGCTGGAGCAGCC
CGCCTAGAACCCAGTCTAATGAGAACTCCAGAAAGCTGGAGCAGCCCACCTAGAGCTGGCCGCGGCCGCCCAGTCTAATAAAAAGAACTC

>61950_61950_3_OTUB1-IRF7_OTUB1_chr11_63764120_ENST00000428192_IRF7_chr11_612800_ENST00000397570_length(amino acids)=226AA_BP=
MQLWSHAVPAEARSRNAAFGDFNFTFLLLSITKSAFQTPGKRKRNWLQEDLQSPPGTLGGWEDGAKPMCGVEGCCQGGATRRGSLPGGRQ
LATRKRSVVRRCLKMAAEEPQQQKQEPLGSDSEGVNCLAYDEAIMAQQDRIQQEIAVQNPLVSERLELSVLYKEYAEDDNIYQQKIKDLH

--------------------------------------------------------------
>61950_61950_4_OTUB1-IRF7_OTUB1_chr11_63764120_ENST00000428192_IRF7_chr11_612800_ENST00000397574_length(transcript)=903nt_BP=661nt
GCTGCTCCGCACTGCAGCTATGGTCGCATGCAGTGCCTGCCGAAGCCCGCAGCAGGAATGCTGCCTTCGGTGATTTTAATTTCACTTTTC
TACTTCTCTCAATAACAAAATCCGCGTTTCAAACTCCAGGGAAAAGAAAACGGAATTGGCTCCAGGAGGATCTGCAATCACCACCGGGAA
CTTTGGGAGGCTGGGAAGATGGAGCCAAACCAATGTGTGGGGTGGAGGGCTGTTGCCAAGGCGGGGCAACGAGGAGGGGCTCGCTTCCGG
GAGGACGGCAATTGGCAACCCGGAAGCGGTCGGTAGTGCGGCGCTGTTTAAAGATGGCGGCGGAGGAACCTCAGCAGCAGAAGCAGGAGC
CGCTGGGCAGCGACTCCGAAGGTGTTAACTGTCTGGCCTATGATGAAGCCATCATGGCTCAGCAGGACCGAATTCAGCAAGAGATTGCTG
TGCAGAACCCTCTGGTGTCAGAGCGGCTGGAGCTCTCGGTCCTATACAAGGAGTATGCTGAAGATGACAACATCTATCAACAGAAGATCA
AGGACCTCCACAAAAAGTACTCGTACATCCGCAAGACCAGGCCTGACGGCAACTGTTTCTATCGGGCTTTCGGATTCTCCCACTTGGAGG
CACTGCTGGATGACAGCAAGGAGTTGCAGCGCTGGAACCCTGGCTGTGCCGAGTGCACCTAGAGGGCACGCAGCGTGAGGGTGTGTCTTC
CCTGGATAGCAGCAGCCTCAGCCTCTGCCTGTCCAGCGCCAACAGCCTCTATGACGACATCGAGTGCTTCCTTATGGAGCTGGAGCAGCC
CGCCTAGAACCCAGTCTAATGAGAACTCCAGAAAGCTGGAGCAGCCCACCTAGAGCTGGCCGCGGCCGCCCAGTCTAATAAAAAGAACTC

>61950_61950_4_OTUB1-IRF7_OTUB1_chr11_63764120_ENST00000428192_IRF7_chr11_612800_ENST00000397574_length(amino acids)=226AA_BP=
MQLWSHAVPAEARSRNAAFGDFNFTFLLLSITKSAFQTPGKRKRNWLQEDLQSPPGTLGGWEDGAKPMCGVEGCCQGGATRRGSLPGGRQ
LATRKRSVVRRCLKMAAEEPQQQKQEPLGSDSEGVNCLAYDEAIMAQQDRIQQEIAVQNPLVSERLELSVLYKEYAEDDNIYQQKIKDLH

--------------------------------------------------------------
>61950_61950_5_OTUB1-IRF7_OTUB1_chr11_63764120_ENST00000535715_IRF7_chr11_612800_ENST00000397570_length(transcript)=1036nt_BP=790nt
GTCAGATGCTGCTCCGCACTGCAGCTATGGTCGCATGCAGTGCCTGCCGAAGCCCGCAGCAGGAATGCTGCCTTCGGTGATTTTAATTTC
ACTTTTCTACTTCTCTCAATAACAAAATCCGCGTTTCAAACTCCAGGGAAAAGAAAACGGAATTGGCTCCAGGAGGATCTGCAATCACCA
CCGGGAACTTTGGGAGGCTGGGAAGATGGAGCCAAACCAATGTGTGGGGTGGAGGTGCGGATCTGGGGCGGCCGGCCTCTCCTACAGGTC
TCAGGTCCGCAGGCCTGGCGTGCCAGCACCTGCCACGGGACTGGAAGCCCATTCCTTGACAACGCCTAAGGGGATCCCGTTGCTAGGGCT
GTTGCCAAGGCGGGGCAACGAGGAGGGGCTCGCTTCCGGGAGGACGGCAATTGGCAACCCGGAAGCGGTCGGTAGTGCGGCGCTGTTTAA
AGATGGCGGCGGAGGAACCTCAGCAGCAGAAGCAGGAGCCGCTGGGCAGCGACTCCGAAGGTGTTAACTGTCTGGCCTATGATGAAGCCA
TCATGGCTCAGCAGGACCGAATTCAGCAAGAGATTGCTGTGCAGAACCCTCTGGTGTCAGAGCGGCTGGAGCTCTCGGTCCTATACAAGG
AGTATGCTGAAGATGACAACATCTATCAACAGAAGATCAAGGACCTCCACAAAAAGTACTCGTACATCCGCAAGACCAGGCCTGACGGCA
ACTGTTTCTATCGGGCTTTCGGATTCTCCCACTTGGAGGCACTGCTGGATGACAGCAAGGAGTTGCAGCGCTGGAACCCTGGCTGTGCCG
AGTGCACCTAGAGGGCACGCAGCGTGAGGGTGTGTCTTCCCTGGATAGCAGCAGCCTCAGCCTCTGCCTGTCCAGCGCCAACAGCCTCTA
TGACGACATCGAGTGCTTCCTTATGGAGCTGGAGCAGCCCGCCTAGAACCCAGTCTAATGAGAACTCCAGAAAGCTGGAGCAGCCCACCT

>61950_61950_5_OTUB1-IRF7_OTUB1_chr11_63764120_ENST00000535715_IRF7_chr11_612800_ENST00000397570_length(amino acids)=136AA_BP=
MATRKRSVVRRCLKMAAEEPQQQKQEPLGSDSEGVNCLAYDEAIMAQQDRIQQEIAVQNPLVSERLELSVLYKEYAEDDNIYQQKIKDLH

--------------------------------------------------------------
>61950_61950_6_OTUB1-IRF7_OTUB1_chr11_63764120_ENST00000535715_IRF7_chr11_612800_ENST00000397574_length(transcript)=1032nt_BP=790nt
GTCAGATGCTGCTCCGCACTGCAGCTATGGTCGCATGCAGTGCCTGCCGAAGCCCGCAGCAGGAATGCTGCCTTCGGTGATTTTAATTTC
ACTTTTCTACTTCTCTCAATAACAAAATCCGCGTTTCAAACTCCAGGGAAAAGAAAACGGAATTGGCTCCAGGAGGATCTGCAATCACCA
CCGGGAACTTTGGGAGGCTGGGAAGATGGAGCCAAACCAATGTGTGGGGTGGAGGTGCGGATCTGGGGCGGCCGGCCTCTCCTACAGGTC
TCAGGTCCGCAGGCCTGGCGTGCCAGCACCTGCCACGGGACTGGAAGCCCATTCCTTGACAACGCCTAAGGGGATCCCGTTGCTAGGGCT
GTTGCCAAGGCGGGGCAACGAGGAGGGGCTCGCTTCCGGGAGGACGGCAATTGGCAACCCGGAAGCGGTCGGTAGTGCGGCGCTGTTTAA
AGATGGCGGCGGAGGAACCTCAGCAGCAGAAGCAGGAGCCGCTGGGCAGCGACTCCGAAGGTGTTAACTGTCTGGCCTATGATGAAGCCA
TCATGGCTCAGCAGGACCGAATTCAGCAAGAGATTGCTGTGCAGAACCCTCTGGTGTCAGAGCGGCTGGAGCTCTCGGTCCTATACAAGG
AGTATGCTGAAGATGACAACATCTATCAACAGAAGATCAAGGACCTCCACAAAAAGTACTCGTACATCCGCAAGACCAGGCCTGACGGCA
ACTGTTTCTATCGGGCTTTCGGATTCTCCCACTTGGAGGCACTGCTGGATGACAGCAAGGAGTTGCAGCGCTGGAACCCTGGCTGTGCCG
AGTGCACCTAGAGGGCACGCAGCGTGAGGGTGTGTCTTCCCTGGATAGCAGCAGCCTCAGCCTCTGCCTGTCCAGCGCCAACAGCCTCTA
TGACGACATCGAGTGCTTCCTTATGGAGCTGGAGCAGCCCGCCTAGAACCCAGTCTAATGAGAACTCCAGAAAGCTGGAGCAGCCCACCT

>61950_61950_6_OTUB1-IRF7_OTUB1_chr11_63764120_ENST00000535715_IRF7_chr11_612800_ENST00000397574_length(amino acids)=136AA_BP=
MATRKRSVVRRCLKMAAEEPQQQKQEPLGSDSEGVNCLAYDEAIMAQQDRIQQEIAVQNPLVSERLELSVLYKEYAEDDNIYQQKIKDLH

--------------------------------------------------------------
>61950_61950_7_OTUB1-IRF7_OTUB1_chr11_63764120_ENST00000538426_IRF7_chr11_612800_ENST00000397570_length(transcript)=628nt_BP=382nt
AATTGGCAACCCGGAAGCGGTCGGTAGTGCGGCGCTGTTTAAAGATGGCGGCGGAGGAACCTCAGCAGCAGAAGCAGGAGCCGCTGGGCA
GCGACTCCGAAGGTGTTAACTGTCTGGCCTATGATGAAGCCATCATGGCTCAGCAGGACCGAATTCAGCAAGAGATTGCTGTGCAGAACC
CTCTGGTGTCAGAGCGGCTGGAGCTCTCGGTCCTATACAAGGAGTATGCTGAAGATGACAACATCTATCAACAGAAGATCAAGGACCTCC
ACAAAAAGTACTCGTACATCCGCAAGACCAGGCCTGACGGCAACTGTTTCTATCGGGCTTTCGGATTCTCCCACTTGGAGGCACTGCTGG
ATGACAGCAAGGAGTTGCAGCGCTGGAACCCTGGCTGTGCCGAGTGCACCTAGAGGGCACGCAGCGTGAGGGTGTGTCTTCCCTGGATAG
CAGCAGCCTCAGCCTCTGCCTGTCCAGCGCCAACAGCCTCTATGACGACATCGAGTGCTTCCTTATGGAGCTGGAGCAGCCCGCCTAGAA

>61950_61950_7_OTUB1-IRF7_OTUB1_chr11_63764120_ENST00000538426_IRF7_chr11_612800_ENST00000397570_length(amino acids)=136AA_BP=
LATRKRSVVRRCLKMAAEEPQQQKQEPLGSDSEGVNCLAYDEAIMAQQDRIQQEIAVQNPLVSERLELSVLYKEYAEDDNIYQQKIKDLH

--------------------------------------------------------------
>61950_61950_8_OTUB1-IRF7_OTUB1_chr11_63764120_ENST00000538426_IRF7_chr11_612800_ENST00000397574_length(transcript)=624nt_BP=382nt
AATTGGCAACCCGGAAGCGGTCGGTAGTGCGGCGCTGTTTAAAGATGGCGGCGGAGGAACCTCAGCAGCAGAAGCAGGAGCCGCTGGGCA
GCGACTCCGAAGGTGTTAACTGTCTGGCCTATGATGAAGCCATCATGGCTCAGCAGGACCGAATTCAGCAAGAGATTGCTGTGCAGAACC
CTCTGGTGTCAGAGCGGCTGGAGCTCTCGGTCCTATACAAGGAGTATGCTGAAGATGACAACATCTATCAACAGAAGATCAAGGACCTCC
ACAAAAAGTACTCGTACATCCGCAAGACCAGGCCTGACGGCAACTGTTTCTATCGGGCTTTCGGATTCTCCCACTTGGAGGCACTGCTGG
ATGACAGCAAGGAGTTGCAGCGCTGGAACCCTGGCTGTGCCGAGTGCACCTAGAGGGCACGCAGCGTGAGGGTGTGTCTTCCCTGGATAG
CAGCAGCCTCAGCCTCTGCCTGTCCAGCGCCAACAGCCTCTATGACGACATCGAGTGCTTCCTTATGGAGCTGGAGCAGCCCGCCTAGAA

>61950_61950_8_OTUB1-IRF7_OTUB1_chr11_63764120_ENST00000538426_IRF7_chr11_612800_ENST00000397574_length(amino acids)=136AA_BP=
LATRKRSVVRRCLKMAAEEPQQQKQEPLGSDSEGVNCLAYDEAIMAQQDRIQQEIAVQNPLVSERLELSVLYKEYAEDDNIYQQKIKDLH

--------------------------------------------------------------
>61950_61950_9_OTUB1-IRF7_OTUB1_chr11_63764120_ENST00000543004_IRF7_chr11_612800_ENST00000397570_length(transcript)=622nt_BP=376nt
GCTGTTTAAAGATGGCGGCGGAGGAACCTCAGCAGCAGAAGCAGGAGCCGCTGGGCAGCGACTCCGAAGGTGTTAACTGTCTGGCCTATG
ATGAAGCCATCATGGCTCAGCAGGACCGAATTCAGCAAGAGGACATGACAGATCCCTGCCTCCTCCAGATTGCTGTGCAGAACCCTCTGG
TGTCAGAGCGGCTGGAGCTCTCGGTCCTATACAAGGAGTATGCTGAAGATGACAACATCTATCAACAGAAGATCAAGGACCTCCACAAAA
AGTACTCGTACATCCGCAAGACCAGGCCTGACGGCAACTGTTTCTATCGGGCTTTCGGATTCTCCCACTTGGAGGCACTGCTGGATGACA
GCAAGGAGTTGCAGCGCTGGAACCCTGGCTGTGCCGAGTGCACCTAGAGGGCACGCAGCGTGAGGGTGTGTCTTCCCTGGATAGCAGCAG
CCTCAGCCTCTGCCTGTCCAGCGCCAACAGCCTCTATGACGACATCGAGTGCTTCCTTATGGAGCTGGAGCAGCCCGCCTAGAACCCAGT

>61950_61950_9_OTUB1-IRF7_OTUB1_chr11_63764120_ENST00000543004_IRF7_chr11_612800_ENST00000397570_length(amino acids)=131AA_BP=
MAAEEPQQQKQEPLGSDSEGVNCLAYDEAIMAQQDRIQQEDMTDPCLLQIAVQNPLVSERLELSVLYKEYAEDDNIYQQKIKDLHKKYSY

--------------------------------------------------------------
>61950_61950_10_OTUB1-IRF7_OTUB1_chr11_63764120_ENST00000543004_IRF7_chr11_612800_ENST00000397574_length(transcript)=618nt_BP=376nt
GCTGTTTAAAGATGGCGGCGGAGGAACCTCAGCAGCAGAAGCAGGAGCCGCTGGGCAGCGACTCCGAAGGTGTTAACTGTCTGGCCTATG
ATGAAGCCATCATGGCTCAGCAGGACCGAATTCAGCAAGAGGACATGACAGATCCCTGCCTCCTCCAGATTGCTGTGCAGAACCCTCTGG
TGTCAGAGCGGCTGGAGCTCTCGGTCCTATACAAGGAGTATGCTGAAGATGACAACATCTATCAACAGAAGATCAAGGACCTCCACAAAA
AGTACTCGTACATCCGCAAGACCAGGCCTGACGGCAACTGTTTCTATCGGGCTTTCGGATTCTCCCACTTGGAGGCACTGCTGGATGACA
GCAAGGAGTTGCAGCGCTGGAACCCTGGCTGTGCCGAGTGCACCTAGAGGGCACGCAGCGTGAGGGTGTGTCTTCCCTGGATAGCAGCAG
CCTCAGCCTCTGCCTGTCCAGCGCCAACAGCCTCTATGACGACATCGAGTGCTTCCTTATGGAGCTGGAGCAGCCCGCCTAGAACCCAGT

>61950_61950_10_OTUB1-IRF7_OTUB1_chr11_63764120_ENST00000543004_IRF7_chr11_612800_ENST00000397574_length(amino acids)=131AA_BP=
MAAEEPQQQKQEPLGSDSEGVNCLAYDEAIMAQQDRIQQEDMTDPCLLQIAVQNPLVSERLELSVLYKEYAEDDNIYQQKIKDLHKKYSY

--------------------------------------------------------------
>61950_61950_11_OTUB1-IRF7_OTUB1_chr11_63764120_ENST00000543988_IRF7_chr11_612800_ENST00000397570_length(transcript)=723nt_BP=477nt
CCTTGCAGTCAGGCAGAGAGGCCTACGCCAGGGCCGAGCCCCCCGGCCTGCTCCAGCGGCGGCCCGCGCCGTGAGGGCCTCGAGTTTCGC
TGGGCTACGGAGCACAAAGGTCCGGGCGGGCCATTCGGGATGTCGTAGGCGGCCCTGGGATGTGAGGGGCCTGCGGGATCTGTCCCTGAG
GCCTGCGACTTTTTCTGGTGTTAACTGTCTGGCCTATGATGAAGCCATCATGGCTCAGCAGGACCGAATTCAGCAAGAGATTGCTGTGCA
GAACCCTCTGGTGTCAGAGCGGCTGGAGCTCTCGGTCCTATACAAGGAGTATGCTGAAGATGACAACATCTATCAACAGAAGATCAAGGA
CCTCCACAAAAAGTACTCGTACATCCGCAAGACCAGGCCTGACGGCAACTGTTTCTATCGGGCTTTCGGATTCTCCCACTTGGAGGCACT
GCTGGATGACAGCAAGGAGTTGCAGCGCTGGAACCCTGGCTGTGCCGAGTGCACCTAGAGGGCACGCAGCGTGAGGGTGTGTCTTCCCTG
GATAGCAGCAGCCTCAGCCTCTGCCTGTCCAGCGCCAACAGCCTCTATGACGACATCGAGTGCTTCCTTATGGAGCTGGAGCAGCCCGCC
TAGAACCCAGTCTAATGAGAACTCCAGAAAGCTGGAGCAGCCCACCTAGAGCTGGCCGCGGCCGCCCAGTCTAATAAAAAGAACTCCAGA

>61950_61950_11_OTUB1-IRF7_OTUB1_chr11_63764120_ENST00000543988_IRF7_chr11_612800_ENST00000397570_length(amino acids)=115AA_BP=
MRDLSLRPATFSGVNCLAYDEAIMAQQDRIQQEIAVQNPLVSERLELSVLYKEYAEDDNIYQQKIKDLHKKYSYIRKTRPDGNCFYRAFG

--------------------------------------------------------------
>61950_61950_12_OTUB1-IRF7_OTUB1_chr11_63764120_ENST00000543988_IRF7_chr11_612800_ENST00000397574_length(transcript)=719nt_BP=477nt
CCTTGCAGTCAGGCAGAGAGGCCTACGCCAGGGCCGAGCCCCCCGGCCTGCTCCAGCGGCGGCCCGCGCCGTGAGGGCCTCGAGTTTCGC
TGGGCTACGGAGCACAAAGGTCCGGGCGGGCCATTCGGGATGTCGTAGGCGGCCCTGGGATGTGAGGGGCCTGCGGGATCTGTCCCTGAG
GCCTGCGACTTTTTCTGGTGTTAACTGTCTGGCCTATGATGAAGCCATCATGGCTCAGCAGGACCGAATTCAGCAAGAGATTGCTGTGCA
GAACCCTCTGGTGTCAGAGCGGCTGGAGCTCTCGGTCCTATACAAGGAGTATGCTGAAGATGACAACATCTATCAACAGAAGATCAAGGA
CCTCCACAAAAAGTACTCGTACATCCGCAAGACCAGGCCTGACGGCAACTGTTTCTATCGGGCTTTCGGATTCTCCCACTTGGAGGCACT
GCTGGATGACAGCAAGGAGTTGCAGCGCTGGAACCCTGGCTGTGCCGAGTGCACCTAGAGGGCACGCAGCGTGAGGGTGTGTCTTCCCTG
GATAGCAGCAGCCTCAGCCTCTGCCTGTCCAGCGCCAACAGCCTCTATGACGACATCGAGTGCTTCCTTATGGAGCTGGAGCAGCCCGCC

>61950_61950_12_OTUB1-IRF7_OTUB1_chr11_63764120_ENST00000543988_IRF7_chr11_612800_ENST00000397574_length(amino acids)=115AA_BP=
MRDLSLRPATFSGVNCLAYDEAIMAQQDRIQQEIAVQNPLVSERLELSVLYKEYAEDDNIYQQKIKDLHKKYSYIRKTRPDGNCFYRAFG

--------------------------------------------------------------

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Fusion Gene PPI Analysis for OTUB1-IRF7


check button Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in

ChiPPI page.


check button Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160)
HgeneHgene's interactorsTgeneTgene's interactors


check button - Retained PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenStill interaction with


check button - Lost PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


check button - Retained PPIs, but lost function due to frame-shift fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


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Related Drugs for OTUB1-IRF7


check button Drugs targeting genes involved in this fusion gene.
(DrugBank Version 5.1.8 2021-05-08)
PartnerGeneUniProtAccDrugBank IDDrug nameDrug activityDrug typeDrug status

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Related Diseases for OTUB1-IRF7


check button Diseases associated with fusion partners.
(DisGeNet 4.0)
PartnerGeneDisease IDDisease name# pubmedsSource