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Center for Computational Systems Medicine
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Fusion Gene Summary

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Fusion Gene ORF analysis

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Fusion Genomic Features

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Fusion Protein Features

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Fusion Gene Sequence

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Fusion Gene PPI analysis

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Related Drugs

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Related Diseases

Fusion gene:PALM2-LPAR1 (FusionGDB2 ID:62494)

Fusion Gene Summary for PALM2-LPAR1

check button Fusion gene summary
Fusion gene informationFusion gene name: PALM2-LPAR1
Fusion gene ID: 62494
HgeneTgene
Gene symbol

PALM2

LPAR1

Gene ID

445815

1902

Gene namePALM2 and AKAP2 fusionlysophosphatidic acid receptor 1
SynonymsAKAP-2|AKAP-KL|AKAP2|AKAPKL|MISP2|PALM2|PALM2-AKAP2|PRKA2EDG2|GPR26|Gpcr26|LPA1|Mrec1.3|VZG1|edg-2|rec.1.3|vzg-1
Cytomap

9q31.3

9q31.3

Type of geneprotein-codingprotein-coding
DescriptionA-kinase anchor protein 2PALM2-AKAP2 proteinparalemmin-2A kinase (PRKA) anchor protein 2A-kinase anchoring protein 2PALM2-AKAP2 fusionPALM2-AKAP2 readthroughparalemmin 2protein kinase A anchoring protein 2protein kinase A2lysophosphatidic acid receptor 1LPA receptor 1LPA-1endothelial differentiation, lysophosphatidic acid G-protein-coupled receptor, 2lysophosphatidic acid receptor Edg-2ventricular zone gene 1
Modification date2020031320200313
UniProtAcc.

Q92633

Ensembl transtripts involved in fusion geneENST00000314527, ENST00000374531, 
ENST00000448454, ENST00000483909, 
ENST00000358883, ENST00000374430, 
ENST00000374431, ENST00000538760, 
ENST00000541779, 
Fusion gene scores* DoF score4 X 4 X 4=6410 X 6 X 6=360
# samples 511
** MAII scorelog2(5/64*10)=-0.356143810225275
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0		log2(11/360*10)=-1.71049338280502
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0
Context

PubMed: PALM2 [Title/Abstract] AND LPAR1 [Title/Abstract] AND fusion [Title/Abstract]

Most frequent breakpointPALM2(112542813)-LPAR1(113638002), # samples:1
Anticipated loss of major functional domain due to fusion event.PALM2-LPAR1 seems lost the major protein functional domain in Tgene partner, which is a essential gene due to the frame-shifted ORF.
PALM2-LPAR1 seems lost the major protein functional domain in Tgene partner, which is a IUPHAR drug target due to the frame-shifted ORF.
* DoF score (Degree of Frequency) = # partners X # break points X # cancer types
** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)

check button Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez
PartnerGeneGO IDGO termPubMed ID
TgeneLPAR1

GO:0007202

activation of phospholipase C activity

19306925


check buttonFusion gene breakpoints across PALM2 (5'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check buttonFusion gene breakpoints across LPAR1 (3'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check button Fusion gene information from two resources (ChiTars 5.0 and ChimerDB 4.0)
* All genome coordinats were lifted-over on hg19.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
SourceDiseaseSampleHgeneHchrHbpHstrandTgeneTchrTbpTstrand
ChimerDB4GBMTCGA-06-5415-01APALM2chr9

112542813

+LPAR1chr9

113638002

-


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Fusion Gene ORF analysis for PALM2-LPAR1

check button Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
ORFHenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrand
Frame-shiftENST00000314527ENST00000358883PALM2chr9

112542813

+LPAR1chr9

113638002

-
Frame-shiftENST00000314527ENST00000374430PALM2chr9

112542813

+LPAR1chr9

113638002

-
Frame-shiftENST00000314527ENST00000374431PALM2chr9

112542813

+LPAR1chr9

113638002

-
Frame-shiftENST00000374531ENST00000358883PALM2chr9

112542813

+LPAR1chr9

113638002

-
Frame-shiftENST00000374531ENST00000374430PALM2chr9

112542813

+LPAR1chr9

113638002

-
Frame-shiftENST00000374531ENST00000374431PALM2chr9

112542813

+LPAR1chr9

113638002

-
Frame-shiftENST00000448454ENST00000358883PALM2chr9

112542813

+LPAR1chr9

113638002

-
Frame-shiftENST00000448454ENST00000374430PALM2chr9

112542813

+LPAR1chr9

113638002

-
Frame-shiftENST00000448454ENST00000374431PALM2chr9

112542813

+LPAR1chr9

113638002

-
Frame-shiftENST00000483909ENST00000358883PALM2chr9

112542813

+LPAR1chr9

113638002

-
Frame-shiftENST00000483909ENST00000374430PALM2chr9

112542813

+LPAR1chr9

113638002

-
Frame-shiftENST00000483909ENST00000374431PALM2chr9

112542813

+LPAR1chr9

113638002

-
In-frameENST00000314527ENST00000538760PALM2chr9

112542813

+LPAR1chr9

113638002

-
In-frameENST00000314527ENST00000541779PALM2chr9

112542813

+LPAR1chr9

113638002

-
In-frameENST00000374531ENST00000538760PALM2chr9

112542813

+LPAR1chr9

113638002

-
In-frameENST00000374531ENST00000541779PALM2chr9

112542813

+LPAR1chr9

113638002

-
In-frameENST00000448454ENST00000538760PALM2chr9

112542813

+LPAR1chr9

113638002

-
In-frameENST00000448454ENST00000541779PALM2chr9

112542813

+LPAR1chr9

113638002

-
In-frameENST00000483909ENST00000538760PALM2chr9

112542813

+LPAR1chr9

113638002

-
In-frameENST00000483909ENST00000541779PALM2chr9

112542813

+LPAR1chr9

113638002

-

check buttonORFfinder result based on the fusion transcript sequence of in-frame fusion genes.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandSeq length
(transcript)		BP loci
(transcript)		Predicted start
(transcript)		Predicted stop
(transcript)		Seq length
(amino acids)
ENST00000374531PALM2chr9112542813+ENST00000541779LPAR1chr9113638002-258412522571922111
ENST00000374531PALM2chr9112542813+ENST00000538760LPAR1chr9113638002-67212515442690
ENST00000448454PALM2chr9112542813+ENST00000541779LPAR1chr9113638002-25105121831848111
ENST00000448454PALM2chr9112542813+ENST00000538760LPAR1chr9113638002-598518035290
ENST00000483909PALM2chr9112542813+ENST00000541779LPAR1chr9113638002-259013167432121
ENST00000483909PALM2chr9112542813+ENST00000538760LPAR1chr9113638002-67813167432121
ENST00000314527PALM2chr9112542813+ENST00000541779LPAR1chr9113638002-25549531396121
ENST00000314527PALM2chr9112542813+ENST00000538760LPAR1chr9113638002-6429531396121

check buttonDeepORF prediction of the coding potential based on the fusion transcript sequence of in-frame fusion genes. DeepORF is a coding potential classifier based on convolutional neural network by comparing the real Ribo-seq data. If the no-coding score < 0.5 and coding score > 0.5, then the in-frame fusion transcript is predicted as being likely translated.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandNo-coding scoreCoding score
ENST00000374531ENST00000541779PALM2chr9112542813+LPAR1chr9113638002-0.6893840.31061605
ENST00000374531ENST00000538760PALM2chr9112542813+LPAR1chr9113638002-0.182321250.81767875
ENST00000448454ENST00000541779PALM2chr9112542813+LPAR1chr9113638002-0.79701690.20298307
ENST00000448454ENST00000538760PALM2chr9112542813+LPAR1chr9113638002-0.214202480.7857975
ENST00000483909ENST00000541779PALM2chr9112542813+LPAR1chr9113638002-0.862103460.13789655
ENST00000483909ENST00000538760PALM2chr9112542813+LPAR1chr9113638002-0.55555940.44444057
ENST00000314527ENST00000541779PALM2chr9112542813+LPAR1chr9113638002-0.764219340.23578061
ENST00000314527ENST00000538760PALM2chr9112542813+LPAR1chr9113638002-0.50602850.4939715

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Fusion Genomic Features for PALM2-LPAR1


check buttonFusionAI prediction of the potential fusion gene breakpoint based on the pre-mature RNA sequence context (+/- 5kb of individual partner genes, total 20kb length sequence). FusionAI is a fusion gene breakpoint classifier based on convolutional neural network by comparing the fusion positive and negative sequence context of ~ 20K fusion gene data. From here, we can have the relative potentency of the 20K genomic sequence how individual sequnce will be likely used as the gene fusion breakpoints.
HgeneHchrHbpHstrandTgeneTchrTbpTstrand1-pp (fusion gene breakpoint)

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions. We integrated a total of 44 different types of human genomic feature loci information across five big categories including virus integration sites, repeats, structural variants, chromatin states, and gene expression regulation. More details are in help page.
genomic feature

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions that are ovelapped with the top 1% feature importance score regions. More details are in help page.

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Fusion Protein Features for PALM2-LPAR1


check button Four levels of functional features of fusion genes
Go to FGviewer search page for the most frequent breakpoint (https://ccsmweb.uth.edu/FGviewer/chr9:112542813/chr9:113638002)
- FGviewer provides the online visualization of the retention search of the protein functional features across DNA, RNA, protein, and pathological levels.
- How to search
1. Put your fusion gene symbol.
2. Press the tab key until there will be shown the breakpoint information filled.
4. Go down and press 'Search' tab twice.
4. Go down to have the hyperlink of the search result.
5. Click the hyperlink.
6. See the FGviewer result for your fusion gene.
FGviewer

check buttonMain function of each fusion partner protein. (from UniProt)
HgeneTgene
.LPAR1

Q92633

FUNCTION: Transcriptional activator which is required for calcium-dependent dendritic growth and branching in cortical neurons. Recruits CREB-binding protein (CREBBP) to nuclear bodies. Component of the CREST-BRG1 complex, a multiprotein complex that regulates promoter activation by orchestrating a calcium-dependent release of a repressor complex and a recruitment of an activator complex. In resting neurons, transcription of the c-FOS promoter is inhibited by BRG1-dependent recruitment of a phospho-RB1-HDAC1 repressor complex. Upon calcium influx, RB1 is dephosphorylated by calcineurin, which leads to release of the repressor complex. At the same time, there is increased recruitment of CREBBP to the promoter by a CREST-dependent mechanism, which leads to transcriptional activation. The CREST-BRG1 complex also binds to the NR2B promoter, and activity-dependent induction of NR2B expression involves a release of HDAC1 and recruitment of CREBBP (By similarity). {ECO:0000250}.FUNCTION: Receptor for lysophosphatidic acid (LPA) (PubMed:9070858, PubMed:19306925, PubMed:25025571, PubMed:26091040). Plays a role in the reorganization of the actin cytoskeleton, cell migration, differentiation and proliferation, and thereby contributes to the responses to tissue damage and infectious agents. Activates downstream signaling cascades via the G(i)/G(o), G(12)/G(13), and G(q) families of heteromeric G proteins. Signaling inhibits adenylyl cyclase activity and decreases cellular cAMP levels (PubMed:26091040). Signaling triggers an increase of cytoplasmic Ca(2+) levels (PubMed:19656035, PubMed:19733258, PubMed:26091040). Activates RALA; this leads to the activation of phospholipase C (PLC) and the formation of inositol 1,4,5-trisphosphate (PubMed:19306925). Signaling mediates activation of down-stream MAP kinases (By similarity). Contributes to the regulation of cell shape. Promotes Rho-dependent reorganization of the actin cytoskeleton in neuronal cells and neurite retraction (PubMed:26091040). Promotes the activation of Rho and the formation of actin stress fibers (PubMed:26091040). Promotes formation of lamellipodia at the leading edge of migrating cells via activation of RAC1 (By similarity). Through its function as lysophosphatidic acid receptor, plays a role in chemotaxis and cell migration, including responses to injury and wounding (PubMed:18066075, PubMed:19656035, PubMed:19733258). Plays a role in triggering inflammation in response to bacterial lipopolysaccharide (LPS) via its interaction with CD14. Promotes cell proliferation in response to lysophosphatidic acid. Required for normal skeleton development. May play a role in osteoblast differentiation. Required for normal brain development. Required for normal proliferation, survival and maturation of newly formed neurons in the adult dentate gyrus. Plays a role in pain perception and in the initiation of neuropathic pain (By similarity). {ECO:0000250|UniProtKB:P61793, ECO:0000269|PubMed:18066075, ECO:0000269|PubMed:19306925, ECO:0000269|PubMed:19656035, ECO:0000269|PubMed:19733258, ECO:0000269|PubMed:25025571, ECO:0000269|PubMed:26091040, ECO:0000269|PubMed:9070858, ECO:0000305|PubMed:11093753, ECO:0000305|PubMed:9069262}.

check buttonRetention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at

download page


* Minus value of BPloci means that the break pointn is located before the CDS.
- In-frame and retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
TgeneLPAR1chr9:112542813chr9:113638002ENST0000035888324281_294264365.0Topological domainNote=Extracellular
TgeneLPAR1chr9:112542813chr9:113638002ENST0000035888324316_364264365.0Topological domainNote=Cytoplasmic
TgeneLPAR1chr9:112542813chr9:113638002ENST0000037443035281_294264365.0Topological domainNote=Extracellular
TgeneLPAR1chr9:112542813chr9:113638002ENST0000037443035316_364264365.0Topological domainNote=Cytoplasmic
TgeneLPAR1chr9:112542813chr9:113638002ENST0000037443135281_294264365.0Topological domainNote=Extracellular
TgeneLPAR1chr9:112542813chr9:113638002ENST0000037443135316_364264365.0Topological domainNote=Cytoplasmic
TgeneLPAR1chr9:112542813chr9:113638002ENST0000035888324295_315264365.0TransmembraneNote=Helical%3B Name%3D7
TgeneLPAR1chr9:112542813chr9:113638002ENST0000037443035295_315264365.0TransmembraneNote=Helical%3B Name%3D7
TgeneLPAR1chr9:112542813chr9:113638002ENST0000037443135295_315264365.0TransmembraneNote=Helical%3B Name%3D7

- In-frame and not-retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgenePALM2chr9:112542813chr9:113638002ENST00000314527+172_3715412.0Coiled coilOntology_term=ECO:0000255
HgenePALM2chr9:112542813chr9:113638002ENST00000314527+1769_11015412.0Coiled coilOntology_term=ECO:0000255
HgenePALM2chr9:112542813chr9:113638002ENST00000374531+272_3717380.0Coiled coilOntology_term=ECO:0000255
HgenePALM2chr9:112542813chr9:113638002ENST00000374531+2769_11017380.0Coiled coilOntology_term=ECO:0000255
TgeneLPAR1chr9:112542813chr9:113638002ENST0000035888324124_129264365.0RegionLysophosphatidic acid binding
TgeneLPAR1chr9:112542813chr9:113638002ENST0000037443035124_129264365.0RegionLysophosphatidic acid binding
TgeneLPAR1chr9:112542813chr9:113638002ENST0000037443135124_129264365.0RegionLysophosphatidic acid binding
TgeneLPAR1chr9:112542813chr9:113638002ENST0000035888324108_121264365.0Topological domainNote=Extracellular
TgeneLPAR1chr9:112542813chr9:113638002ENST0000035888324145_163264365.0Topological domainNote=Cytoplasmic
TgeneLPAR1chr9:112542813chr9:113638002ENST0000035888324185_204264365.0Topological domainNote=Extracellular
TgeneLPAR1chr9:112542813chr9:113638002ENST00000358883241_50264365.0Topological domainNote=Extracellular
TgeneLPAR1chr9:112542813chr9:113638002ENST0000035888324226_255264365.0Topological domainNote=Cytoplasmic
TgeneLPAR1chr9:112542813chr9:113638002ENST000003588832476_83264365.0Topological domainNote=Cytoplasmic
TgeneLPAR1chr9:112542813chr9:113638002ENST0000037443035108_121264365.0Topological domainNote=Extracellular
TgeneLPAR1chr9:112542813chr9:113638002ENST0000037443035145_163264365.0Topological domainNote=Cytoplasmic
TgeneLPAR1chr9:112542813chr9:113638002ENST0000037443035185_204264365.0Topological domainNote=Extracellular
TgeneLPAR1chr9:112542813chr9:113638002ENST00000374430351_50264365.0Topological domainNote=Extracellular
TgeneLPAR1chr9:112542813chr9:113638002ENST0000037443035226_255264365.0Topological domainNote=Cytoplasmic
TgeneLPAR1chr9:112542813chr9:113638002ENST000003744303576_83264365.0Topological domainNote=Cytoplasmic
TgeneLPAR1chr9:112542813chr9:113638002ENST0000037443135108_121264365.0Topological domainNote=Extracellular
TgeneLPAR1chr9:112542813chr9:113638002ENST0000037443135145_163264365.0Topological domainNote=Cytoplasmic
TgeneLPAR1chr9:112542813chr9:113638002ENST0000037443135185_204264365.0Topological domainNote=Extracellular
TgeneLPAR1chr9:112542813chr9:113638002ENST00000374431351_50264365.0Topological domainNote=Extracellular
TgeneLPAR1chr9:112542813chr9:113638002ENST0000037443135226_255264365.0Topological domainNote=Cytoplasmic
TgeneLPAR1chr9:112542813chr9:113638002ENST000003744313576_83264365.0Topological domainNote=Cytoplasmic
TgeneLPAR1chr9:112542813chr9:113638002ENST0000035888324122_144264365.0TransmembraneNote=Helical%3B Name%3D3
TgeneLPAR1chr9:112542813chr9:113638002ENST0000035888324164_184264365.0TransmembraneNote=Helical%3B Name%3D4
TgeneLPAR1chr9:112542813chr9:113638002ENST0000035888324205_225264365.0TransmembraneNote=Helical%3B Name%3D5
TgeneLPAR1chr9:112542813chr9:113638002ENST0000035888324256_280264365.0TransmembraneNote=Helical%3B Name%3D6
TgeneLPAR1chr9:112542813chr9:113638002ENST000003588832451_75264365.0TransmembraneNote=Helical%3B Name%3D1
TgeneLPAR1chr9:112542813chr9:113638002ENST000003588832484_107264365.0TransmembraneNote=Helical%3B Name%3D2
TgeneLPAR1chr9:112542813chr9:113638002ENST0000037443035122_144264365.0TransmembraneNote=Helical%3B Name%3D3
TgeneLPAR1chr9:112542813chr9:113638002ENST0000037443035164_184264365.0TransmembraneNote=Helical%3B Name%3D4
TgeneLPAR1chr9:112542813chr9:113638002ENST0000037443035205_225264365.0TransmembraneNote=Helical%3B Name%3D5
TgeneLPAR1chr9:112542813chr9:113638002ENST0000037443035256_280264365.0TransmembraneNote=Helical%3B Name%3D6
TgeneLPAR1chr9:112542813chr9:113638002ENST000003744303551_75264365.0TransmembraneNote=Helical%3B Name%3D1
TgeneLPAR1chr9:112542813chr9:113638002ENST000003744303584_107264365.0TransmembraneNote=Helical%3B Name%3D2
TgeneLPAR1chr9:112542813chr9:113638002ENST0000037443135122_144264365.0TransmembraneNote=Helical%3B Name%3D3
TgeneLPAR1chr9:112542813chr9:113638002ENST0000037443135164_184264365.0TransmembraneNote=Helical%3B Name%3D4
TgeneLPAR1chr9:112542813chr9:113638002ENST0000037443135205_225264365.0TransmembraneNote=Helical%3B Name%3D5
TgeneLPAR1chr9:112542813chr9:113638002ENST0000037443135256_280264365.0TransmembraneNote=Helical%3B Name%3D6
TgeneLPAR1chr9:112542813chr9:113638002ENST000003744313551_75264365.0TransmembraneNote=Helical%3B Name%3D1
TgeneLPAR1chr9:112542813chr9:113638002ENST000003744313584_107264365.0TransmembraneNote=Helical%3B Name%3D2


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Fusion Gene Sequence for PALM2-LPAR1


check button For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. To have fusion amino acid sequence, we ran ORFfinder and chose the longest ORF among the all predicted ones.
>62494_62494_1_PALM2-LPAR1_PALM2_chr9_112542813_ENST00000314527_LPAR1_chr9_113638002_ENST00000538760_length(transcript)=642nt_BP=95nt
GCGTGTGTTTTTTCTTTCCTCTTTCCCCTGCCTGTGTGCCCTTCTCCAGGATGGCAGAGGCGGAATTGCACAAGGAAAGGCTGCAAGCCA
TAGCAGGGCCTTTATCATCTGCTGGACTCCTGGATTGGTTTTGTTACTTCTAGACGTGTGCTGTCCACAGTGCGACGTGCTGGCCTATGA
GAAATTCTTCCTTCTCCTTGCTGAATTCAACTCTGCCATGAACCCCATCATTTACTCCTACCGCGACAAAGAAATGAGCGCCACCTTTAG
GCAGATCCTCTGCTGCCAGCGCAGTGAGAACCCCACCGGCCCCACAGAAGGCTCAGACCGCTCGGCTTCCTCCCTCAACCACACCATCTT
GGCTGGAGTTCACAGCAATGACCACTCTGTGGTTTAGAACGGAAACTGAGATGAGGAACCAGCCGTCCTCTCTTGGAGGATAAACAGCCT
CCCCCTACCCAATTGCCAGGGCAAGGTGGGGTGTGAGAGAGGAGAAAAGTCAACTCATGTACTTAAACACTAACCAATGACAGTATTTGT
TCCTGGACCCCACAAGACTTGATATATATTGAAAATTAGCTTATGTGACAACCCTCATCTTGATCCCCATCCCTTCTGAAAGTAGGAAGT

>62494_62494_1_PALM2-LPAR1_PALM2_chr9_112542813_ENST00000314527_LPAR1_chr9_113638002_ENST00000538760_length(amino acids)=121AA_BP=22
MCALLQDGRGGIAQGKAASHSRAFIICWTPGLVLLLLDVCCPQCDVLAYEKFFLLLAEFNSAMNPIIYSYRDKEMSATFRQILCCQRSEN

--------------------------------------------------------------
>62494_62494_2_PALM2-LPAR1_PALM2_chr9_112542813_ENST00000314527_LPAR1_chr9_113638002_ENST00000541779_length(transcript)=2554nt_BP=95nt
GCGTGTGTTTTTTCTTTCCTCTTTCCCCTGCCTGTGTGCCCTTCTCCAGGATGGCAGAGGCGGAATTGCACAAGGAAAGGCTGCAAGCCA
TAGCAGGGCCTTTATCATCTGCTGGACTCCTGGATTGGTTTTGTTACTTCTAGACGTGTGCTGTCCACAGTGCGACGTGCTGGCCTATGA
GAAATTCTTCCTTCTCCTTGCTGAATTCAACTCTGCCATGAACCCCATCATTTACTCCTACCGCGACAAAGAAATGAGCGCCACCTTTAG
GCAGATCCTCTGCTGCCAGCGCAGTGAGAACCCCACCGGCCCCACAGAAGGCTCAGACCGCTCGGCTTCCTCCCTCAACCACACCATCTT
GGCTGGAGTTCACAGCAATGACCACTCTGTGGTTTAGAACGGAAACTGAGATGAGGAACCAGCCGTCCTCTCTTGGAGGATAAACAGCCT
CCCCCTACCCAATTGCCAGGGCAAGGTGGGGTGTGAGAGAGGAGAAAAGTCAACTCATGTACTTAAACACTAACCAATGACAGTATTTGT
TCCTGGACCCCACAAGACTTGATATATATTGAAAATTAGCTTATGTGACAACCCTCATCTTGATCCCCATCCCTTCTGAAAGTAGGAAGT
TGGAGCTCTTGCAATGGAATTCAAGAACAGACTCTGGAGTGTCCATTTAGACTACACTAACTAGACTTTTAAAAGATTTTGTGTGGTTTG
GTGCAAGTCAGAATAAATTCTGGCTAGTTGAATCCACAACTTCATTTATATACAGGCTTCCCTTTTTTATTTTTAAAGGATACGTTTCAC
TTAATAAACACGTTTATGCCTATCAGCATGTTTGTGATGGATGAGACTATGGACTGCTTTTAAACTACCATAATTCCATTTTTTCCCTTA
CATAGGAAAACTGTAAGTTGGAATTATCTTTTGTTTAGAAAGCATGCATGTAATGTATGTATGCAGTATGCCTTACTTAAAAAGATTAAA
AGGATACTAATGTTAAATCTTCTAGGAAATAGAACCTAGACTTCAAAGCCAGTATTTGTTTAGGTCATGAAGCAAACAATGCTCTAATCA
CAATATTAACTGTTTAATTAAAATGTTGTAACAAGTATAAAACAGGGAATGTAAGTTTATTACCAAAGTGATATGTATTCCAAAAAAGTC
ATAGAAGATGAAGCACTATAATATTGTTCCCATATATTTAAAATACCCAAGTACATTCTAATTACCAGTATATCAGAGGAAAATTTTCGT
AGTCTTTGTAAAATAATATACTCATCATAGAAAACTTGAAAAATGCAGAAATGTATAAAAAAGCAAAAATGATTACTGATAATATCACAA
CCCAGAAGTAACCACCTTTAAAAAGCAACCCCCATGTATGCCTATATGTGTATTGTATACTTTTTTTACATAATTGGAGTCATACTGTAA
ACAGTTTTATAAGTAGATCTTTTTCATTGCAAAATTGCCACATTTTCTTATGGCATTAAAAATTTTACAAAAACATAATTTTAATGGCTA
TATTATATTCCATTTAATGGATGCAACTCAGTTTATTTAACCATTCCCATGTTGTTAACTATTTAGGTTGTTTCTAATTTTCATTATTAT
AAAGTTGCAGAAATTTGGTGTACATAAAACTGTCTCCATATAATTGATTATTAGGATATATTCCCATGAAGGATTCTTTTTTTAAAAAAA
TGTGAAATGTCATCTTGTACTTACACCTTTCATGAAAAGGGATTTCCTGCTTTTGTACTGCATGGGTGGCAGTTGTGAGGAAAAGCCAGT
CAAATGACCTTTTTACAAAAGAAATGCAGTGGTCACTTCAGTTGAGAGTGACTTTTTAATACAACAAGATCAACTAGAAGAATTCAACTG
TCTCAAGAATCAAGGTACCCCAATATATCTCGCAATTCCAAACTTTGTTTGAGGGACTCGTTATCCAGCTCTTGGTAGCCACACCTGCAA
TGTAAAATGGAAGAAAATGCAAAGAAACCAAATGTGCCGAGTGAATAAAGGATTGTCATATCAATTAGTGTGGGTCCATCTGTAGCAAAT
GGGTTGAGTGTGTCAGTATGTGGTTGGTTACTGTGTATTCGCCAGGAATCACCCCGATAGGCTGCCACCCTATTAGGTGATACCTGTTTA
ATATGTTGTCCAGGTAGACTAGTAGTTGCATCAGTTTGCTGTAACAAGTAACCAGTGAGGTAACACAGTGGTGAAGCAGGTCAGGGGAGG
TCAGGAGGATGTCTGAGAGAAAGAAGTCCGGGAGATGAATGGCTGTCTAGGAAGGAGGATGTCAGTGCACGGTTAGTGTTTGAGCAGAGG
GCAGACTTGTAAAGTACCTGTAGTGAAAAGAATGTGGGGACCCGATTAGCAGAAAGGTGTTTGCACGTACTTTATACAAAATACAGAATA
CTTTATATTGGAAGTGAAAGAAATGAACGTGGACTTTTACACATGTGCATATTTTTCTGGAGGCTATATGGATTATTTGAAATGAAAAGC

>62494_62494_2_PALM2-LPAR1_PALM2_chr9_112542813_ENST00000314527_LPAR1_chr9_113638002_ENST00000541779_length(amino acids)=121AA_BP=22
MCALLQDGRGGIAQGKAASHSRAFIICWTPGLVLLLLDVCCPQCDVLAYEKFFLLLAEFNSAMNPIIYSYRDKEMSATFRQILCCQRSEN

--------------------------------------------------------------
>62494_62494_3_PALM2-LPAR1_PALM2_chr9_112542813_ENST00000374531_LPAR1_chr9_113638002_ENST00000538760_length(transcript)=672nt_BP=125nt
GTGCACTCGGCTCCGGGAGAGGCGAGCAGCGCCGGTGAGCCCCGCAGCAGCGCACCCGGCCGCGGAGCCCCGCGATGGAGATGGCAGAGG
CGGAATTGCACAAGGAAAGGCTGCAAGCCATAGCAGGGCCTTTATCATCTGCTGGACTCCTGGATTGGTTTTGTTACTTCTAGACGTGTG
CTGTCCACAGTGCGACGTGCTGGCCTATGAGAAATTCTTCCTTCTCCTTGCTGAATTCAACTCTGCCATGAACCCCATCATTTACTCCTA
CCGCGACAAAGAAATGAGCGCCACCTTTAGGCAGATCCTCTGCTGCCAGCGCAGTGAGAACCCCACCGGCCCCACAGAAGGCTCAGACCG
CTCGGCTTCCTCCCTCAACCACACCATCTTGGCTGGAGTTCACAGCAATGACCACTCTGTGGTTTAGAACGGAAACTGAGATGAGGAACC
AGCCGTCCTCTCTTGGAGGATAAACAGCCTCCCCCTACCCAATTGCCAGGGCAAGGTGGGGTGTGAGAGAGGAGAAAAGTCAACTCATGT
ACTTAAACACTAACCAATGACAGTATTTGTTCCTGGACCCCACAAGACTTGATATATATTGAAAATTAGCTTATGTGACAACCCTCATCT

>62494_62494_3_PALM2-LPAR1_PALM2_chr9_112542813_ENST00000374531_LPAR1_chr9_113638002_ENST00000538760_length(amino acids)=90AA_BP=
MVLLLLDVCCPQCDVLAYEKFFLLLAEFNSAMNPIIYSYRDKEMSATFRQILCCQRSENPTGPTEGSDRSASSLNHTILAGVHSNDHSVV

--------------------------------------------------------------
>62494_62494_4_PALM2-LPAR1_PALM2_chr9_112542813_ENST00000374531_LPAR1_chr9_113638002_ENST00000541779_length(transcript)=2584nt_BP=125nt
GTGCACTCGGCTCCGGGAGAGGCGAGCAGCGCCGGTGAGCCCCGCAGCAGCGCACCCGGCCGCGGAGCCCCGCGATGGAGATGGCAGAGG
CGGAATTGCACAAGGAAAGGCTGCAAGCCATAGCAGGGCCTTTATCATCTGCTGGACTCCTGGATTGGTTTTGTTACTTCTAGACGTGTG
CTGTCCACAGTGCGACGTGCTGGCCTATGAGAAATTCTTCCTTCTCCTTGCTGAATTCAACTCTGCCATGAACCCCATCATTTACTCCTA
CCGCGACAAAGAAATGAGCGCCACCTTTAGGCAGATCCTCTGCTGCCAGCGCAGTGAGAACCCCACCGGCCCCACAGAAGGCTCAGACCG
CTCGGCTTCCTCCCTCAACCACACCATCTTGGCTGGAGTTCACAGCAATGACCACTCTGTGGTTTAGAACGGAAACTGAGATGAGGAACC
AGCCGTCCTCTCTTGGAGGATAAACAGCCTCCCCCTACCCAATTGCCAGGGCAAGGTGGGGTGTGAGAGAGGAGAAAAGTCAACTCATGT
ACTTAAACACTAACCAATGACAGTATTTGTTCCTGGACCCCACAAGACTTGATATATATTGAAAATTAGCTTATGTGACAACCCTCATCT
TGATCCCCATCCCTTCTGAAAGTAGGAAGTTGGAGCTCTTGCAATGGAATTCAAGAACAGACTCTGGAGTGTCCATTTAGACTACACTAA
CTAGACTTTTAAAAGATTTTGTGTGGTTTGGTGCAAGTCAGAATAAATTCTGGCTAGTTGAATCCACAACTTCATTTATATACAGGCTTC
CCTTTTTTATTTTTAAAGGATACGTTTCACTTAATAAACACGTTTATGCCTATCAGCATGTTTGTGATGGATGAGACTATGGACTGCTTT
TAAACTACCATAATTCCATTTTTTCCCTTACATAGGAAAACTGTAAGTTGGAATTATCTTTTGTTTAGAAAGCATGCATGTAATGTATGT
ATGCAGTATGCCTTACTTAAAAAGATTAAAAGGATACTAATGTTAAATCTTCTAGGAAATAGAACCTAGACTTCAAAGCCAGTATTTGTT
TAGGTCATGAAGCAAACAATGCTCTAATCACAATATTAACTGTTTAATTAAAATGTTGTAACAAGTATAAAACAGGGAATGTAAGTTTAT
TACCAAAGTGATATGTATTCCAAAAAAGTCATAGAAGATGAAGCACTATAATATTGTTCCCATATATTTAAAATACCCAAGTACATTCTA
ATTACCAGTATATCAGAGGAAAATTTTCGTAGTCTTTGTAAAATAATATACTCATCATAGAAAACTTGAAAAATGCAGAAATGTATAAAA
AAGCAAAAATGATTACTGATAATATCACAACCCAGAAGTAACCACCTTTAAAAAGCAACCCCCATGTATGCCTATATGTGTATTGTATAC
TTTTTTTACATAATTGGAGTCATACTGTAAACAGTTTTATAAGTAGATCTTTTTCATTGCAAAATTGCCACATTTTCTTATGGCATTAAA
AATTTTACAAAAACATAATTTTAATGGCTATATTATATTCCATTTAATGGATGCAACTCAGTTTATTTAACCATTCCCATGTTGTTAACT
ATTTAGGTTGTTTCTAATTTTCATTATTATAAAGTTGCAGAAATTTGGTGTACATAAAACTGTCTCCATATAATTGATTATTAGGATATA
TTCCCATGAAGGATTCTTTTTTTAAAAAAATGTGAAATGTCATCTTGTACTTACACCTTTCATGAAAAGGGATTTCCTGCTTTTGTACTG
CATGGGTGGCAGTTGTGAGGAAAAGCCAGTCAAATGACCTTTTTACAAAAGAAATGCAGTGGTCACTTCAGTTGAGAGTGACTTTTTAAT
ACAACAAGATCAACTAGAAGAATTCAACTGTCTCAAGAATCAAGGTACCCCAATATATCTCGCAATTCCAAACTTTGTTTGAGGGACTCG
TTATCCAGCTCTTGGTAGCCACACCTGCAATGTAAAATGGAAGAAAATGCAAAGAAACCAAATGTGCCGAGTGAATAAAGGATTGTCATA
TCAATTAGTGTGGGTCCATCTGTAGCAAATGGGTTGAGTGTGTCAGTATGTGGTTGGTTACTGTGTATTCGCCAGGAATCACCCCGATAG
GCTGCCACCCTATTAGGTGATACCTGTTTAATATGTTGTCCAGGTAGACTAGTAGTTGCATCAGTTTGCTGTAACAAGTAACCAGTGAGG
TAACACAGTGGTGAAGCAGGTCAGGGGAGGTCAGGAGGATGTCTGAGAGAAAGAAGTCCGGGAGATGAATGGCTGTCTAGGAAGGAGGAT
GTCAGTGCACGGTTAGTGTTTGAGCAGAGGGCAGACTTGTAAAGTACCTGTAGTGAAAAGAATGTGGGGACCCGATTAGCAGAAAGGTGT
TTGCACGTACTTTATACAAAATACAGAATACTTTATATTGGAAGTGAAAGAAATGAACGTGGACTTTTACACATGTGCATATTTTTCTGG

>62494_62494_4_PALM2-LPAR1_PALM2_chr9_112542813_ENST00000374531_LPAR1_chr9_113638002_ENST00000541779_length(amino acids)=111AA_BP=
MCYLTGYLLQQTDATTSLPGQHIKQVSPNRVAAYRGDSWRIHSNQPHTDTLNPFATDGPTLIDMTILYSLGTFGFFAFSSILHCRCGYQE

--------------------------------------------------------------
>62494_62494_5_PALM2-LPAR1_PALM2_chr9_112542813_ENST00000448454_LPAR1_chr9_113638002_ENST00000538760_length(transcript)=598nt_BP=51nt
ATGGAGATGGCAGAGGCGGAATTGCACAAGGAAAGGCTGCAAGCCATAGCAGGGCCTTTATCATCTGCTGGACTCCTGGATTGGTTTTGT
TACTTCTAGACGTGTGCTGTCCACAGTGCGACGTGCTGGCCTATGAGAAATTCTTCCTTCTCCTTGCTGAATTCAACTCTGCCATGAACC
CCATCATTTACTCCTACCGCGACAAAGAAATGAGCGCCACCTTTAGGCAGATCCTCTGCTGCCAGCGCAGTGAGAACCCCACCGGCCCCA
CAGAAGGCTCAGACCGCTCGGCTTCCTCCCTCAACCACACCATCTTGGCTGGAGTTCACAGCAATGACCACTCTGTGGTTTAGAACGGAA
ACTGAGATGAGGAACCAGCCGTCCTCTCTTGGAGGATAAACAGCCTCCCCCTACCCAATTGCCAGGGCAAGGTGGGGTGTGAGAGAGGAG
AAAAGTCAACTCATGTACTTAAACACTAACCAATGACAGTATTTGTTCCTGGACCCCACAAGACTTGATATATATTGAAAATTAGCTTAT

>62494_62494_5_PALM2-LPAR1_PALM2_chr9_112542813_ENST00000448454_LPAR1_chr9_113638002_ENST00000538760_length(amino acids)=90AA_BP=
MVLLLLDVCCPQCDVLAYEKFFLLLAEFNSAMNPIIYSYRDKEMSATFRQILCCQRSENPTGPTEGSDRSASSLNHTILAGVHSNDHSVV

--------------------------------------------------------------
>62494_62494_6_PALM2-LPAR1_PALM2_chr9_112542813_ENST00000448454_LPAR1_chr9_113638002_ENST00000541779_length(transcript)=2510nt_BP=51nt
ATGGAGATGGCAGAGGCGGAATTGCACAAGGAAAGGCTGCAAGCCATAGCAGGGCCTTTATCATCTGCTGGACTCCTGGATTGGTTTTGT
TACTTCTAGACGTGTGCTGTCCACAGTGCGACGTGCTGGCCTATGAGAAATTCTTCCTTCTCCTTGCTGAATTCAACTCTGCCATGAACC
CCATCATTTACTCCTACCGCGACAAAGAAATGAGCGCCACCTTTAGGCAGATCCTCTGCTGCCAGCGCAGTGAGAACCCCACCGGCCCCA
CAGAAGGCTCAGACCGCTCGGCTTCCTCCCTCAACCACACCATCTTGGCTGGAGTTCACAGCAATGACCACTCTGTGGTTTAGAACGGAA
ACTGAGATGAGGAACCAGCCGTCCTCTCTTGGAGGATAAACAGCCTCCCCCTACCCAATTGCCAGGGCAAGGTGGGGTGTGAGAGAGGAG
AAAAGTCAACTCATGTACTTAAACACTAACCAATGACAGTATTTGTTCCTGGACCCCACAAGACTTGATATATATTGAAAATTAGCTTAT
GTGACAACCCTCATCTTGATCCCCATCCCTTCTGAAAGTAGGAAGTTGGAGCTCTTGCAATGGAATTCAAGAACAGACTCTGGAGTGTCC
ATTTAGACTACACTAACTAGACTTTTAAAAGATTTTGTGTGGTTTGGTGCAAGTCAGAATAAATTCTGGCTAGTTGAATCCACAACTTCA
TTTATATACAGGCTTCCCTTTTTTATTTTTAAAGGATACGTTTCACTTAATAAACACGTTTATGCCTATCAGCATGTTTGTGATGGATGA
GACTATGGACTGCTTTTAAACTACCATAATTCCATTTTTTCCCTTACATAGGAAAACTGTAAGTTGGAATTATCTTTTGTTTAGAAAGCA
TGCATGTAATGTATGTATGCAGTATGCCTTACTTAAAAAGATTAAAAGGATACTAATGTTAAATCTTCTAGGAAATAGAACCTAGACTTC
AAAGCCAGTATTTGTTTAGGTCATGAAGCAAACAATGCTCTAATCACAATATTAACTGTTTAATTAAAATGTTGTAACAAGTATAAAACA
GGGAATGTAAGTTTATTACCAAAGTGATATGTATTCCAAAAAAGTCATAGAAGATGAAGCACTATAATATTGTTCCCATATATTTAAAAT
ACCCAAGTACATTCTAATTACCAGTATATCAGAGGAAAATTTTCGTAGTCTTTGTAAAATAATATACTCATCATAGAAAACTTGAAAAAT
GCAGAAATGTATAAAAAAGCAAAAATGATTACTGATAATATCACAACCCAGAAGTAACCACCTTTAAAAAGCAACCCCCATGTATGCCTA
TATGTGTATTGTATACTTTTTTTACATAATTGGAGTCATACTGTAAACAGTTTTATAAGTAGATCTTTTTCATTGCAAAATTGCCACATT
TTCTTATGGCATTAAAAATTTTACAAAAACATAATTTTAATGGCTATATTATATTCCATTTAATGGATGCAACTCAGTTTATTTAACCAT
TCCCATGTTGTTAACTATTTAGGTTGTTTCTAATTTTCATTATTATAAAGTTGCAGAAATTTGGTGTACATAAAACTGTCTCCATATAAT
TGATTATTAGGATATATTCCCATGAAGGATTCTTTTTTTAAAAAAATGTGAAATGTCATCTTGTACTTACACCTTTCATGAAAAGGGATT
TCCTGCTTTTGTACTGCATGGGTGGCAGTTGTGAGGAAAAGCCAGTCAAATGACCTTTTTACAAAAGAAATGCAGTGGTCACTTCAGTTG
AGAGTGACTTTTTAATACAACAAGATCAACTAGAAGAATTCAACTGTCTCAAGAATCAAGGTACCCCAATATATCTCGCAATTCCAAACT
TTGTTTGAGGGACTCGTTATCCAGCTCTTGGTAGCCACACCTGCAATGTAAAATGGAAGAAAATGCAAAGAAACCAAATGTGCCGAGTGA
ATAAAGGATTGTCATATCAATTAGTGTGGGTCCATCTGTAGCAAATGGGTTGAGTGTGTCAGTATGTGGTTGGTTACTGTGTATTCGCCA
GGAATCACCCCGATAGGCTGCCACCCTATTAGGTGATACCTGTTTAATATGTTGTCCAGGTAGACTAGTAGTTGCATCAGTTTGCTGTAA
CAAGTAACCAGTGAGGTAACACAGTGGTGAAGCAGGTCAGGGGAGGTCAGGAGGATGTCTGAGAGAAAGAAGTCCGGGAGATGAATGGCT
GTCTAGGAAGGAGGATGTCAGTGCACGGTTAGTGTTTGAGCAGAGGGCAGACTTGTAAAGTACCTGTAGTGAAAAGAATGTGGGGACCCG
ATTAGCAGAAAGGTGTTTGCACGTACTTTATACAAAATACAGAATACTTTATATTGGAAGTGAAAGAAATGAACGTGGACTTTTACACAT

>62494_62494_6_PALM2-LPAR1_PALM2_chr9_112542813_ENST00000448454_LPAR1_chr9_113638002_ENST00000541779_length(amino acids)=111AA_BP=
MCYLTGYLLQQTDATTSLPGQHIKQVSPNRVAAYRGDSWRIHSNQPHTDTLNPFATDGPTLIDMTILYSLGTFGFFAFSSILHCRCGYQE

--------------------------------------------------------------
>62494_62494_7_PALM2-LPAR1_PALM2_chr9_112542813_ENST00000483909_LPAR1_chr9_113638002_ENST00000538760_length(transcript)=678nt_BP=131nt
CCCCGGGGTGCCCATCAGTTTCCTTGGGTGACTACAGCGTGTGTTTTTTCTTTCCTCTTTCCCCTGCCTGTGTGCCCTTCTCCAGGATGG
CAGAGGCGGAATTGCACAAGGAAAGGCTGCAAGCCATAGCAGGGCCTTTATCATCTGCTGGACTCCTGGATTGGTTTTGTTACTTCTAGA
CGTGTGCTGTCCACAGTGCGACGTGCTGGCCTATGAGAAATTCTTCCTTCTCCTTGCTGAATTCAACTCTGCCATGAACCCCATCATTTA
CTCCTACCGCGACAAAGAAATGAGCGCCACCTTTAGGCAGATCCTCTGCTGCCAGCGCAGTGAGAACCCCACCGGCCCCACAGAAGGCTC
AGACCGCTCGGCTTCCTCCCTCAACCACACCATCTTGGCTGGAGTTCACAGCAATGACCACTCTGTGGTTTAGAACGGAAACTGAGATGA
GGAACCAGCCGTCCTCTCTTGGAGGATAAACAGCCTCCCCCTACCCAATTGCCAGGGCAAGGTGGGGTGTGAGAGAGGAGAAAAGTCAAC
TCATGTACTTAAACACTAACCAATGACAGTATTTGTTCCTGGACCCCACAAGACTTGATATATATTGAAAATTAGCTTATGTGACAACCC

>62494_62494_7_PALM2-LPAR1_PALM2_chr9_112542813_ENST00000483909_LPAR1_chr9_113638002_ENST00000538760_length(amino acids)=121AA_BP=22
MCALLQDGRGGIAQGKAASHSRAFIICWTPGLVLLLLDVCCPQCDVLAYEKFFLLLAEFNSAMNPIIYSYRDKEMSATFRQILCCQRSEN

--------------------------------------------------------------
>62494_62494_8_PALM2-LPAR1_PALM2_chr9_112542813_ENST00000483909_LPAR1_chr9_113638002_ENST00000541779_length(transcript)=2590nt_BP=131nt
CCCCGGGGTGCCCATCAGTTTCCTTGGGTGACTACAGCGTGTGTTTTTTCTTTCCTCTTTCCCCTGCCTGTGTGCCCTTCTCCAGGATGG
CAGAGGCGGAATTGCACAAGGAAAGGCTGCAAGCCATAGCAGGGCCTTTATCATCTGCTGGACTCCTGGATTGGTTTTGTTACTTCTAGA
CGTGTGCTGTCCACAGTGCGACGTGCTGGCCTATGAGAAATTCTTCCTTCTCCTTGCTGAATTCAACTCTGCCATGAACCCCATCATTTA
CTCCTACCGCGACAAAGAAATGAGCGCCACCTTTAGGCAGATCCTCTGCTGCCAGCGCAGTGAGAACCCCACCGGCCCCACAGAAGGCTC
AGACCGCTCGGCTTCCTCCCTCAACCACACCATCTTGGCTGGAGTTCACAGCAATGACCACTCTGTGGTTTAGAACGGAAACTGAGATGA
GGAACCAGCCGTCCTCTCTTGGAGGATAAACAGCCTCCCCCTACCCAATTGCCAGGGCAAGGTGGGGTGTGAGAGAGGAGAAAAGTCAAC
TCATGTACTTAAACACTAACCAATGACAGTATTTGTTCCTGGACCCCACAAGACTTGATATATATTGAAAATTAGCTTATGTGACAACCC
TCATCTTGATCCCCATCCCTTCTGAAAGTAGGAAGTTGGAGCTCTTGCAATGGAATTCAAGAACAGACTCTGGAGTGTCCATTTAGACTA
CACTAACTAGACTTTTAAAAGATTTTGTGTGGTTTGGTGCAAGTCAGAATAAATTCTGGCTAGTTGAATCCACAACTTCATTTATATACA
GGCTTCCCTTTTTTATTTTTAAAGGATACGTTTCACTTAATAAACACGTTTATGCCTATCAGCATGTTTGTGATGGATGAGACTATGGAC
TGCTTTTAAACTACCATAATTCCATTTTTTCCCTTACATAGGAAAACTGTAAGTTGGAATTATCTTTTGTTTAGAAAGCATGCATGTAAT
GTATGTATGCAGTATGCCTTACTTAAAAAGATTAAAAGGATACTAATGTTAAATCTTCTAGGAAATAGAACCTAGACTTCAAAGCCAGTA
TTTGTTTAGGTCATGAAGCAAACAATGCTCTAATCACAATATTAACTGTTTAATTAAAATGTTGTAACAAGTATAAAACAGGGAATGTAA
GTTTATTACCAAAGTGATATGTATTCCAAAAAAGTCATAGAAGATGAAGCACTATAATATTGTTCCCATATATTTAAAATACCCAAGTAC
ATTCTAATTACCAGTATATCAGAGGAAAATTTTCGTAGTCTTTGTAAAATAATATACTCATCATAGAAAACTTGAAAAATGCAGAAATGT
ATAAAAAAGCAAAAATGATTACTGATAATATCACAACCCAGAAGTAACCACCTTTAAAAAGCAACCCCCATGTATGCCTATATGTGTATT
GTATACTTTTTTTACATAATTGGAGTCATACTGTAAACAGTTTTATAAGTAGATCTTTTTCATTGCAAAATTGCCACATTTTCTTATGGC
ATTAAAAATTTTACAAAAACATAATTTTAATGGCTATATTATATTCCATTTAATGGATGCAACTCAGTTTATTTAACCATTCCCATGTTG
TTAACTATTTAGGTTGTTTCTAATTTTCATTATTATAAAGTTGCAGAAATTTGGTGTACATAAAACTGTCTCCATATAATTGATTATTAG
GATATATTCCCATGAAGGATTCTTTTTTTAAAAAAATGTGAAATGTCATCTTGTACTTACACCTTTCATGAAAAGGGATTTCCTGCTTTT
GTACTGCATGGGTGGCAGTTGTGAGGAAAAGCCAGTCAAATGACCTTTTTACAAAAGAAATGCAGTGGTCACTTCAGTTGAGAGTGACTT
TTTAATACAACAAGATCAACTAGAAGAATTCAACTGTCTCAAGAATCAAGGTACCCCAATATATCTCGCAATTCCAAACTTTGTTTGAGG
GACTCGTTATCCAGCTCTTGGTAGCCACACCTGCAATGTAAAATGGAAGAAAATGCAAAGAAACCAAATGTGCCGAGTGAATAAAGGATT
GTCATATCAATTAGTGTGGGTCCATCTGTAGCAAATGGGTTGAGTGTGTCAGTATGTGGTTGGTTACTGTGTATTCGCCAGGAATCACCC
CGATAGGCTGCCACCCTATTAGGTGATACCTGTTTAATATGTTGTCCAGGTAGACTAGTAGTTGCATCAGTTTGCTGTAACAAGTAACCA
GTGAGGTAACACAGTGGTGAAGCAGGTCAGGGGAGGTCAGGAGGATGTCTGAGAGAAAGAAGTCCGGGAGATGAATGGCTGTCTAGGAAG
GAGGATGTCAGTGCACGGTTAGTGTTTGAGCAGAGGGCAGACTTGTAAAGTACCTGTAGTGAAAAGAATGTGGGGACCCGATTAGCAGAA
AGGTGTTTGCACGTACTTTATACAAAATACAGAATACTTTATATTGGAAGTGAAAGAAATGAACGTGGACTTTTACACATGTGCATATTT

>62494_62494_8_PALM2-LPAR1_PALM2_chr9_112542813_ENST00000483909_LPAR1_chr9_113638002_ENST00000541779_length(amino acids)=121AA_BP=22
MCALLQDGRGGIAQGKAASHSRAFIICWTPGLVLLLLDVCCPQCDVLAYEKFFLLLAEFNSAMNPIIYSYRDKEMSATFRQILCCQRSEN

--------------------------------------------------------------

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Fusion Gene PPI Analysis for PALM2-LPAR1


check button Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in

ChiPPI page.


check button Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160)
HgeneHgene's interactorsTgeneTgene's interactors


check button - Retained PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenStill interaction with


check button - Lost PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


check button - Retained PPIs, but lost function due to frame-shift fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


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Related Drugs for PALM2-LPAR1


check button Drugs targeting genes involved in this fusion gene.
(DrugBank Version 5.1.8 2021-05-08)
PartnerGeneUniProtAccDrugBank IDDrug nameDrug activityDrug typeDrug status

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Related Diseases for PALM2-LPAR1


check button Diseases associated with fusion partners.
(DisGeNet 4.0)
PartnerGeneDisease IDDisease name# pubmedsSource