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Center for Computational Systems Medicine
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Fusion Gene Summary

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Fusion Gene ORF analysis

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Fusion Genomic Features

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Fusion Protein Features

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Fusion Gene Sequence

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Fusion Gene PPI analysis

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Related Drugs

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Related Diseases

Fusion gene:PAN3-FLT3 (FusionGDB2 ID:62518)

Fusion Gene Summary for PAN3-FLT3

check button Fusion gene summary
Fusion gene informationFusion gene name: PAN3-FLT3
Fusion gene ID: 62518
HgeneTgene
Gene symbol

PAN3

FLT3

Gene ID

255967

2322

Gene namepoly(A) specific ribonuclease subunit PAN3fms related receptor tyrosine kinase 3
Synonyms-CD135|FLK-2|FLK2|STK1
Cytomap

13q12.2

13q12.2

Type of geneprotein-codingprotein-coding
DescriptionPAN2-PAN3 deadenylation complex subunit PAN3PAB-dependent poly(A)-specific ribonuclease subunit 3PAB-dependent poly(A)-specific ribonuclease subunit PAN3PAB1P-dependent poly(A)-nucleasePAB1P-dependent poly(A)-specific ribonucleasePABP-dependent poly(receptor-type tyrosine-protein kinase FLT3CD135 antigenFL cytokine receptorfetal liver kinase 2fms related tyrosine kinase 3fms-like tyrosine kinase 3growth factor receptor tyrosine kinase type IIIstem cell tyrosine kinase 1
Modification date2020032020200329
UniProtAcc.

P49771

Ensembl transtripts involved in fusion geneENST00000380958, ENST00000399613, 
ENST00000282391, ENST00000483842, 
ENST00000469894, ENST00000241453, 
ENST00000380982, ENST00000537084, 
Fusion gene scores* DoF score19 X 9 X 12=20528 X 9 X 5=360
# samples 209
** MAII scorelog2(20/2052*10)=-3.35895882583233
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0		log2(9/360*10)=-2
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0
Context

PubMed: PAN3 [Title/Abstract] AND FLT3 [Title/Abstract] AND fusion [Title/Abstract]

Most frequent breakpointPAN3(28752072)-FLT3(28644749), # samples:3
Anticipated loss of major functional domain due to fusion event.PAN3-FLT3 seems lost the major protein functional domain in Hgene partner, which is a essential gene due to the frame-shifted ORF.
PAN3-FLT3 seems lost the major protein functional domain in Hgene partner, which is a kinase due to the frame-shifted ORF.
PAN3-FLT3 seems lost the major protein functional domain in Tgene partner, which is a CGC due to the frame-shifted ORF.
PAN3-FLT3 seems lost the major protein functional domain in Tgene partner, which is a IUPHAR drug target due to the frame-shifted ORF.
PAN3-FLT3 seems lost the major protein functional domain in Tgene partner, which is a kinase due to the frame-shifted ORF.
PAN3-FLT3 seems lost the major protein functional domain in Tgene partner, which is a tumor suppressor due to the frame-shifted ORF.
* DoF score (Degree of Frequency) = # partners X # break points X # cancer types
** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)

check button Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez
PartnerGeneGO IDGO termPubMed ID
TgeneFLT3

GO:0030097

hemopoiesis

7507245


check buttonFusion gene breakpoints across PAN3 (5'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check buttonFusion gene breakpoints across FLT3 (3'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check button Fusion gene information from two resources (ChiTars 5.0 and ChimerDB 4.0)
* All genome coordinats were lifted-over on hg19.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
SourceDiseaseSampleHgeneHchrHbpHstrandTgeneTchrTbpTstrand
ChimerDB4COADTCGA-AA-3712-01APAN3chr13

28752072

-FLT3chr13

28644749

-
ChimerDB4COADTCGA-AA-3712-01APAN3chr13

28752072

+FLT3chr13

28644749

-
ChimerDB4LAMLTCGA-AB-2853-03APAN3chr13

28794515

+FLT3chr13

28644749

-
ChimerDB4SARCTCGA-HS-A5NA-01APAN3chr13

28713224

+FLT3chr13

28636206

-
ChimerDB4SARCTCGA-HS-A5NA-01APAN3chr13

28713224

-FLT3chr13

28644749

-


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Fusion Gene ORF analysis for PAN3-FLT3

check button Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
ORFHenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrand
5CDS-intronENST00000380958ENST00000469894PAN3chr13

28752072

+FLT3chr13

28644749

-
5CDS-intronENST00000380958ENST00000469894PAN3chr13

28794515

+FLT3chr13

28644749

-
5CDS-intronENST00000380958ENST00000469894PAN3chr13

28713224

+FLT3chr13

28636206

-
5CDS-intronENST00000380958ENST00000469894PAN3chr13

28713224

-FLT3chr13

28644749

-
5CDS-intronENST00000399613ENST00000469894PAN3chr13

28752072

+FLT3chr13

28644749

-
5CDS-intronENST00000399613ENST00000469894PAN3chr13

28794515

+FLT3chr13

28644749

-
5UTR-3CDSENST00000399613ENST00000241453PAN3chr13

28713224

+FLT3chr13

28636206

-
5UTR-3CDSENST00000399613ENST00000241453PAN3chr13

28713224

-FLT3chr13

28644749

-
5UTR-3CDSENST00000399613ENST00000380982PAN3chr13

28713224

+FLT3chr13

28636206

-
5UTR-3CDSENST00000399613ENST00000380982PAN3chr13

28713224

-FLT3chr13

28644749

-
5UTR-3CDSENST00000399613ENST00000537084PAN3chr13

28713224

+FLT3chr13

28636206

-
5UTR-3CDSENST00000399613ENST00000537084PAN3chr13

28713224

-FLT3chr13

28644749

-
5UTR-intronENST00000399613ENST00000469894PAN3chr13

28713224

+FLT3chr13

28636206

-
5UTR-intronENST00000399613ENST00000469894PAN3chr13

28713224

-FLT3chr13

28644749

-
Frame-shiftENST00000380958ENST00000241453PAN3chr13

28752072

+FLT3chr13

28644749

-
Frame-shiftENST00000380958ENST00000241453PAN3chr13

28713224

+FLT3chr13

28636206

-
Frame-shiftENST00000380958ENST00000380982PAN3chr13

28752072

+FLT3chr13

28644749

-
Frame-shiftENST00000380958ENST00000380982PAN3chr13

28713224

+FLT3chr13

28636206

-
Frame-shiftENST00000380958ENST00000537084PAN3chr13

28752072

+FLT3chr13

28644749

-
Frame-shiftENST00000380958ENST00000537084PAN3chr13

28713224

+FLT3chr13

28636206

-
Frame-shiftENST00000399613ENST00000241453PAN3chr13

28752072

+FLT3chr13

28644749

-
Frame-shiftENST00000399613ENST00000380982PAN3chr13

28752072

+FLT3chr13

28644749

-
Frame-shiftENST00000399613ENST00000537084PAN3chr13

28752072

+FLT3chr13

28644749

-
In-frameENST00000380958ENST00000241453PAN3chr13

28794515

+FLT3chr13

28644749

-
In-frameENST00000380958ENST00000241453PAN3chr13

28713224

-FLT3chr13

28644749

-
In-frameENST00000380958ENST00000380982PAN3chr13

28794515

+FLT3chr13

28644749

-
In-frameENST00000380958ENST00000380982PAN3chr13

28713224

-FLT3chr13

28644749

-
In-frameENST00000380958ENST00000537084PAN3chr13

28794515

+FLT3chr13

28644749

-
In-frameENST00000380958ENST00000537084PAN3chr13

28713224

-FLT3chr13

28644749

-
In-frameENST00000399613ENST00000241453PAN3chr13

28794515

+FLT3chr13

28644749

-
In-frameENST00000399613ENST00000380982PAN3chr13

28794515

+FLT3chr13

28644749

-
In-frameENST00000399613ENST00000537084PAN3chr13

28794515

+FLT3chr13

28644749

-
intron-3CDSENST00000282391ENST00000241453PAN3chr13

28752072

+FLT3chr13

28644749

-
intron-3CDSENST00000282391ENST00000241453PAN3chr13

28794515

+FLT3chr13

28644749

-
intron-3CDSENST00000282391ENST00000241453PAN3chr13

28713224

+FLT3chr13

28636206

-
intron-3CDSENST00000282391ENST00000241453PAN3chr13

28713224

-FLT3chr13

28644749

-
intron-3CDSENST00000282391ENST00000380982PAN3chr13

28752072

+FLT3chr13

28644749

-
intron-3CDSENST00000282391ENST00000380982PAN3chr13

28794515

+FLT3chr13

28644749

-
intron-3CDSENST00000282391ENST00000380982PAN3chr13

28713224

+FLT3chr13

28636206

-
intron-3CDSENST00000282391ENST00000380982PAN3chr13

28713224

-FLT3chr13

28644749

-
intron-3CDSENST00000282391ENST00000537084PAN3chr13

28752072

+FLT3chr13

28644749

-
intron-3CDSENST00000282391ENST00000537084PAN3chr13

28794515

+FLT3chr13

28644749

-
intron-3CDSENST00000282391ENST00000537084PAN3chr13

28713224

+FLT3chr13

28636206

-
intron-3CDSENST00000282391ENST00000537084PAN3chr13

28713224

-FLT3chr13

28644749

-
intron-3CDSENST00000483842ENST00000241453PAN3chr13

28752072

+FLT3chr13

28644749

-
intron-3CDSENST00000483842ENST00000241453PAN3chr13

28794515

+FLT3chr13

28644749

-
intron-3CDSENST00000483842ENST00000241453PAN3chr13

28713224

+FLT3chr13

28636206

-
intron-3CDSENST00000483842ENST00000241453PAN3chr13

28713224

-FLT3chr13

28644749

-
intron-3CDSENST00000483842ENST00000380982PAN3chr13

28752072

+FLT3chr13

28644749

-
intron-3CDSENST00000483842ENST00000380982PAN3chr13

28794515

+FLT3chr13

28644749

-
intron-3CDSENST00000483842ENST00000380982PAN3chr13

28713224

+FLT3chr13

28636206

-
intron-3CDSENST00000483842ENST00000380982PAN3chr13

28713224

-FLT3chr13

28644749

-
intron-3CDSENST00000483842ENST00000537084PAN3chr13

28752072

+FLT3chr13

28644749

-
intron-3CDSENST00000483842ENST00000537084PAN3chr13

28794515

+FLT3chr13

28644749

-
intron-3CDSENST00000483842ENST00000537084PAN3chr13

28713224

+FLT3chr13

28636206

-
intron-3CDSENST00000483842ENST00000537084PAN3chr13

28713224

-FLT3chr13

28644749

-
intron-intronENST00000282391ENST00000469894PAN3chr13

28752072

+FLT3chr13

28644749

-
intron-intronENST00000282391ENST00000469894PAN3chr13

28794515

+FLT3chr13

28644749

-
intron-intronENST00000282391ENST00000469894PAN3chr13

28713224

+FLT3chr13

28636206

-
intron-intronENST00000282391ENST00000469894PAN3chr13

28713224

-FLT3chr13

28644749

-
intron-intronENST00000483842ENST00000469894PAN3chr13

28752072

+FLT3chr13

28644749

-
intron-intronENST00000483842ENST00000469894PAN3chr13

28794515

+FLT3chr13

28644749

-
intron-intronENST00000483842ENST00000469894PAN3chr13

28713224

+FLT3chr13

28636206

-
intron-intronENST00000483842ENST00000469894PAN3chr13

28713224

-FLT3chr13

28644749

-

check buttonORFfinder result based on the fusion transcript sequence of in-frame fusion genes.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandSeq length
(transcript)		BP loci
(transcript)		Predicted start
(transcript)		Predicted stop
(transcript)		Seq length
(amino acids)
ENST00000380958PAN3chr1328794515+ENST00000241453FLT3chr1328644749-4869115215240901312
ENST00000380958PAN3chr1328794515+ENST00000380982FLT3chr1328644749-4875115215240991315
ENST00000380958PAN3chr1328794515+ENST00000537084FLT3chr1328644749-4227115215239671271
ENST00000399613PAN3chr1328794515+ENST00000241453FLT3chr1328644749-41804634834011117
ENST00000399613PAN3chr1328794515+ENST00000380982FLT3chr1328644749-41864634834101120
ENST00000399613PAN3chr1328794515+ENST00000537084FLT3chr1328644749-35384634832781076

check buttonDeepORF prediction of the coding potential based on the fusion transcript sequence of in-frame fusion genes. DeepORF is a coding potential classifier based on convolutional neural network by comparing the real Ribo-seq data. If the no-coding score < 0.5 and coding score > 0.5, then the in-frame fusion transcript is predicted as being likely translated.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandNo-coding scoreCoding score
ENST00000380958ENST00000241453PAN3chr1328794515+FLT3chr1328644749-0.0003162760.99968374
ENST00000380958ENST00000380982PAN3chr1328794515+FLT3chr1328644749-0.0002043120.99979573
ENST00000380958ENST00000537084PAN3chr1328794515+FLT3chr1328644749-0.000261090.9997389
ENST00000399613ENST00000241453PAN3chr1328794515+FLT3chr1328644749-0.0002494410.99975055
ENST00000399613ENST00000380982PAN3chr1328794515+FLT3chr1328644749-0.0001580080.9998419
ENST00000399613ENST00000537084PAN3chr1328794515+FLT3chr1328644749-0.0002121160.99978787

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Fusion Genomic Features for PAN3-FLT3


check buttonFusionAI prediction of the potential fusion gene breakpoint based on the pre-mature RNA sequence context (+/- 5kb of individual partner genes, total 20kb length sequence). FusionAI is a fusion gene breakpoint classifier based on convolutional neural network by comparing the fusion positive and negative sequence context of ~ 20K fusion gene data. From here, we can have the relative potentency of the 20K genomic sequence how individual sequnce will be likely used as the gene fusion breakpoints.
HgeneHchrHbpHstrandTgeneTchrTbpTstrand1-pp (fusion gene breakpoint)

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions. We integrated a total of 44 different types of human genomic feature loci information across five big categories including virus integration sites, repeats, structural variants, chromatin states, and gene expression regulation. More details are in help page.
genomic feature

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions that are ovelapped with the top 1% feature importance score regions. More details are in help page.

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Fusion Protein Features for PAN3-FLT3


check button Four levels of functional features of fusion genes
Go to FGviewer search page for the most frequent breakpoint (https://ccsmweb.uth.edu/FGviewer/chr13:28752072/chr13:28644749)
- FGviewer provides the online visualization of the retention search of the protein functional features across DNA, RNA, protein, and pathological levels.
- How to search
1. Put your fusion gene symbol.
2. Press the tab key until there will be shown the breakpoint information filled.
4. Go down and press 'Search' tab twice.
4. Go down to have the hyperlink of the search result.
5. Click the hyperlink.
6. See the FGviewer result for your fusion gene.
FGviewer

check buttonMain function of each fusion partner protein. (from UniProt)
HgeneTgene
.FLT3

P49771

FUNCTION: Transcriptional activator which is required for calcium-dependent dendritic growth and branching in cortical neurons. Recruits CREB-binding protein (CREBBP) to nuclear bodies. Component of the CREST-BRG1 complex, a multiprotein complex that regulates promoter activation by orchestrating a calcium-dependent release of a repressor complex and a recruitment of an activator complex. In resting neurons, transcription of the c-FOS promoter is inhibited by BRG1-dependent recruitment of a phospho-RB1-HDAC1 repressor complex. Upon calcium influx, RB1 is dephosphorylated by calcineurin, which leads to release of the repressor complex. At the same time, there is increased recruitment of CREBBP to the promoter by a CREST-dependent mechanism, which leads to transcriptional activation. The CREST-BRG1 complex also binds to the NR2B promoter, and activity-dependent induction of NR2B expression involves a release of HDAC1 and recruitment of CREBBP (By similarity). {ECO:0000250}.FUNCTION: Stimulates the proliferation of early hematopoietic cells by activating FLT3. Synergizes well with a number of other colony stimulating factors and interleukins.

check buttonRetention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at

download page


* Minus value of BPloci means that the break pointn is located before the CDS.
- In-frame and retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgenePAN3chr13:28794515chr13:28644749ENST00000380958+619284_299333888.0MotifPABPC-interacting motif-2 (PAM-2)
HgenePAN3chr13:28713224chr13:28644749ENST00000380958-11943_71143888.0Zinc fingerC3H1-type
HgenePAN3chr13:28794515chr13:28644749ENST00000380958+61943_71333888.0Zinc fingerC3H1-type
HgenePAN3chr13:28794515chr13:28644749ENST00000399613+51843_71133688.0Zinc fingerC3H1-type
TgeneFLT3chr13:28713224chr13:28644749ENST00000241453024253_34314994.0DomainNote=Ig-like C2-type
TgeneFLT3chr13:28713224chr13:28644749ENST00000241453024610_94314994.0DomainProtein kinase
TgeneFLT3chr13:28713224chr13:28644749ENST00000537084023253_34314953.0DomainNote=Ig-like C2-type
TgeneFLT3chr13:28713224chr13:28644749ENST00000537084023610_94314953.0DomainProtein kinase
TgeneFLT3chr13:28794515chr13:28644749ENST00000241453024253_34314994.0DomainNote=Ig-like C2-type
TgeneFLT3chr13:28794515chr13:28644749ENST00000241453024610_94314994.0DomainProtein kinase
TgeneFLT3chr13:28794515chr13:28644749ENST00000537084023253_34314953.0DomainNote=Ig-like C2-type
TgeneFLT3chr13:28794515chr13:28644749ENST00000537084023610_94314953.0DomainProtein kinase
TgeneFLT3chr13:28713224chr13:28644749ENST00000241453024616_62414994.0Nucleotide bindingATP
TgeneFLT3chr13:28713224chr13:28644749ENST00000537084023616_62414953.0Nucleotide bindingATP
TgeneFLT3chr13:28794515chr13:28644749ENST00000241453024616_62414994.0Nucleotide bindingATP
TgeneFLT3chr13:28794515chr13:28644749ENST00000537084023616_62414953.0Nucleotide bindingATP
TgeneFLT3chr13:28713224chr13:28644749ENST00000241453024591_59714994.0RegionNote=Important for normal regulation of the kinase activity and for maintaining the kinase in an inactive state in the absence of bound ligand
TgeneFLT3chr13:28713224chr13:28644749ENST00000537084023591_59714953.0RegionNote=Important for normal regulation of the kinase activity and for maintaining the kinase in an inactive state in the absence of bound ligand
TgeneFLT3chr13:28794515chr13:28644749ENST00000241453024591_59714994.0RegionNote=Important for normal regulation of the kinase activity and for maintaining the kinase in an inactive state in the absence of bound ligand
TgeneFLT3chr13:28794515chr13:28644749ENST00000537084023591_59714953.0RegionNote=Important for normal regulation of the kinase activity and for maintaining the kinase in an inactive state in the absence of bound ligand
TgeneFLT3chr13:28713224chr13:28644749ENST0000024145302427_54314994.0Topological domainExtracellular
TgeneFLT3chr13:28713224chr13:28644749ENST00000241453024564_99314994.0Topological domainCytoplasmic
TgeneFLT3chr13:28713224chr13:28644749ENST0000053708402327_54314953.0Topological domainExtracellular
TgeneFLT3chr13:28713224chr13:28644749ENST00000537084023564_99314953.0Topological domainCytoplasmic
TgeneFLT3chr13:28794515chr13:28644749ENST0000024145302427_54314994.0Topological domainExtracellular
TgeneFLT3chr13:28794515chr13:28644749ENST00000241453024564_99314994.0Topological domainCytoplasmic
TgeneFLT3chr13:28794515chr13:28644749ENST0000053708402327_54314953.0Topological domainExtracellular
TgeneFLT3chr13:28794515chr13:28644749ENST00000537084023564_99314953.0Topological domainCytoplasmic
TgeneFLT3chr13:28713224chr13:28644749ENST00000241453024544_56314994.0TransmembraneHelical
TgeneFLT3chr13:28713224chr13:28644749ENST00000537084023544_56314953.0TransmembraneHelical
TgeneFLT3chr13:28794515chr13:28644749ENST00000241453024544_56314994.0TransmembraneHelical
TgeneFLT3chr13:28794515chr13:28644749ENST00000537084023544_56314953.0TransmembraneHelical

- In-frame and not-retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgenePAN3chr13:28713224chr13:28644749ENST00000282391-114751_7890576.0Coiled coilOntology_term=ECO:0000255
HgenePAN3chr13:28713224chr13:28644749ENST00000380958-119751_789143888.0Coiled coilOntology_term=ECO:0000255
HgenePAN3chr13:28713224chr13:28644749ENST00000399613-118751_7890688.0Coiled coilOntology_term=ECO:0000255
HgenePAN3chr13:28794515chr13:28644749ENST00000282391+114751_7890576.0Coiled coilOntology_term=ECO:0000255
HgenePAN3chr13:28794515chr13:28644749ENST00000380958+619751_789333888.0Coiled coilOntology_term=ECO:0000255
HgenePAN3chr13:28794515chr13:28644749ENST00000399613+518751_789133688.0Coiled coilOntology_term=ECO:0000255
HgenePAN3chr13:28713224chr13:28644749ENST00000282391-114284_2990576.0MotifPABPC-interacting motif-2 (PAM-2)
HgenePAN3chr13:28713224chr13:28644749ENST00000380958-119284_299143888.0MotifPABPC-interacting motif-2 (PAM-2)
HgenePAN3chr13:28713224chr13:28644749ENST00000399613-118284_2990688.0MotifPABPC-interacting motif-2 (PAM-2)
HgenePAN3chr13:28794515chr13:28644749ENST00000282391+114284_2990576.0MotifPABPC-interacting motif-2 (PAM-2)
HgenePAN3chr13:28794515chr13:28644749ENST00000399613+518284_299133688.0MotifPABPC-interacting motif-2 (PAM-2)
HgenePAN3chr13:28713224chr13:28644749ENST00000282391-114570_5770576.0Nucleotide bindingATP
HgenePAN3chr13:28713224chr13:28644749ENST00000282391-114644_6450576.0Nucleotide bindingATP
HgenePAN3chr13:28713224chr13:28644749ENST00000380958-119570_577143888.0Nucleotide bindingATP
HgenePAN3chr13:28713224chr13:28644749ENST00000380958-119644_645143888.0Nucleotide bindingATP
HgenePAN3chr13:28713224chr13:28644749ENST00000399613-118570_5770688.0Nucleotide bindingATP
HgenePAN3chr13:28713224chr13:28644749ENST00000399613-118644_6450688.0Nucleotide bindingATP
HgenePAN3chr13:28794515chr13:28644749ENST00000282391+114570_5770576.0Nucleotide bindingATP
HgenePAN3chr13:28794515chr13:28644749ENST00000282391+114644_6450576.0Nucleotide bindingATP
HgenePAN3chr13:28794515chr13:28644749ENST00000380958+619570_577333888.0Nucleotide bindingATP
HgenePAN3chr13:28794515chr13:28644749ENST00000380958+619644_645333888.0Nucleotide bindingATP
HgenePAN3chr13:28794515chr13:28644749ENST00000399613+518570_577133688.0Nucleotide bindingATP
HgenePAN3chr13:28794515chr13:28644749ENST00000399613+518644_645133688.0Nucleotide bindingATP
HgenePAN3chr13:28713224chr13:28644749ENST00000282391-114463_7500576.0RegionPseudokinase domain
HgenePAN3chr13:28713224chr13:28644749ENST00000282391-114790_8870576.0RegionKnob domain
HgenePAN3chr13:28713224chr13:28644749ENST00000380958-119463_750143888.0RegionPseudokinase domain
HgenePAN3chr13:28713224chr13:28644749ENST00000380958-119790_887143888.0RegionKnob domain
HgenePAN3chr13:28713224chr13:28644749ENST00000399613-118463_7500688.0RegionPseudokinase domain
HgenePAN3chr13:28713224chr13:28644749ENST00000399613-118790_8870688.0RegionKnob domain
HgenePAN3chr13:28794515chr13:28644749ENST00000282391+114463_7500576.0RegionPseudokinase domain
HgenePAN3chr13:28794515chr13:28644749ENST00000282391+114790_8870576.0RegionKnob domain
HgenePAN3chr13:28794515chr13:28644749ENST00000380958+619463_750333888.0RegionPseudokinase domain
HgenePAN3chr13:28794515chr13:28644749ENST00000380958+619790_887333888.0RegionKnob domain
HgenePAN3chr13:28794515chr13:28644749ENST00000399613+518463_750133688.0RegionPseudokinase domain
HgenePAN3chr13:28794515chr13:28644749ENST00000399613+518790_887133688.0RegionKnob domain
HgenePAN3chr13:28713224chr13:28644749ENST00000282391-11443_710576.0Zinc fingerC3H1-type
HgenePAN3chr13:28713224chr13:28644749ENST00000399613-11843_710688.0Zinc fingerC3H1-type
HgenePAN3chr13:28794515chr13:28644749ENST00000282391+11443_710576.0Zinc fingerC3H1-type


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Fusion Gene Sequence for PAN3-FLT3


check button For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. To have fusion amino acid sequence, we ran ORFfinder and chose the longest ORF among the all predicted ones.
>62518_62518_1_PAN3-FLT3_PAN3_chr13_28794515_ENST00000380958_FLT3_chr13_28644749_ENST00000241453_length(transcript)=4869nt_BP=1152nt
CTCCCCGGGCGGCTCCGGCTCCCGCAGCGGGACAGACCCACCCGCCCAGGCTTTTATCCGGCACCGGCAGCGTCTTCCTTTCCTCCCCCG
TCTATGGTGGTGGCGGCGGCGGCTCCTCGGGCGGCGGCGGAAGACGAGGCTGCGGCGTTGCCATGAACAGTGGCGGCGGCCTCCCGCCCC
CCTCGGCCGCCGCCTCCCCTTCCTCCTCCTCGCTGGCGGCGGCGGTGGCGGTGGTGGCCCCGCCGGGGGTCGGGGGTGTCCCCGGCGGGG
CGGCGGTAGGAGTGAAGCTGAAGTACTGCCGCTACTACGCTAAGGATAAGACTTGCTTCTACGGGGAGGAGTGTCAGTTCCTGCATGAGG
ACCCTGCCGCCGGGGCTGCCCCGGGCCTCGGCCTCCATAGCAACAGCGTCCCCCTGGCTCTGGCTGGTGCACCCGTGGCCGGCTTTCCGC
CGGGAGCCGTCGCGGGCGGGGGAGCTGGGCCGCCCCCCGGGCCCAAGAAGCCGGACCTGGGGGACCCGGGGACCGGAGCCGCAGCCGGCG
GAGGAGGCAGTAGCGGGGGACTCGATGGACCGCGGCTGGCAATTCCAGGAATGGATGGAGGTGCTTTAACTGATACAAGTCTCACAGATT
CCTATTTTAGCACCAGCTTTATTGGAGTCAATGGATTTGGAAGCCCTGTAGAAACAAAATATCCCCTGATGCAGAGAATGACTAATAGTA
GCAGCTCCCCAAGCCTTCTAAATGACAGTGCCAAGCCATATTCAGCCCATGATCCTCTAACATCACCTGCTTCATCCTTGTTTAATGACT
TTGGTGCCCTCAACATCTCTCAGAGACGAAAGCCAAGGAAGTATCGCCTGGGGATGCTGGAGGAGAGGCTAGTTCCGATGGGATCAAAGG
CACGAAAAGCAAAGAACCCTATTGGCTGCCTTGCTGACAGGTGTAAATCAGGAGTACCCATCAATATGGTTTGGTGGAACAGAGTCACAG
AAAACAATTTACAGACACCAAATCCTACTGCAAGCGAGTTTATTCCTAAAGGAGGATCAACCTCCAGGCTGAGTAACGTGTCCCAGTCAA
ATATGTCTGCCTTCTCTCAAGTTTTCTCTCACCCATCCATGGGAAGCCCTGCTACTGCTGGATTAGCGCCAGTTGTTTTTTCTGCAATGA
TATTTGGGACTATTACAAATCAAGATCTGCCTGTGATCAAGTGTGTTTTAATCAATCATAAGAACAATGATTCATCAGTGGGGAAGTCAT
CATCATATCCCATGGTATCAGAATCCCCGGAAGACCTCGGGTGTGCGTTGAGACCCCAGAGCTCAGGGACAGTGTACGAAGCTGCCGCTG
TGGAAGTGGATGTATCTGCTTCCATCACACTGCAAGTGCTGGTCGACGCCCCAGGGAACATTTCCTGTCTCTGGGTCTTTAAGCACAGCT
CCCTGAATTGCCAGCCACATTTTGATTTACAAAACAGAGGAGTTGTTTCCATGGTCATTTTGAAAATGACAGAAACCCAAGCTGGAGAAT
ACCTACTTTTTATTCAGAGTGAAGCTACCAATTACACAATATTGTTTACAGTGAGTATAAGAAATACCCTGCTTTACACATTAAGAAGAC
CTTACTTTAGAAAAATGGAAAACCAGGACGCCCTGGTCTGCATATCTGAGAGCGTTCCAGAGCCGATCGTGGAATGGGTGCTTTGCGATT
CACAGGGGGAAAGCTGTAAAGAAGAAAGTCCAGCTGTTGTTAAAAAGGAGGAAAAAGTGCTTCATGAATTATTTGGGACGGACATAAGGT
GCTGTGCCAGAAATGAACTGGGCAGGGAATGCACCAGGCTGTTCACAATAGATCTAAATCAAACTCCTCAGACCACATTGCCACAATTAT
TTCTTAAAGTAGGGGAACCCTTATGGATAAGGTGCAAAGCTGTTCATGTGAACCATGGATTCGGGCTCACCTGGGAATTAGAAAACAAAG
CACTCGAGGAGGGCAACTACTTTGAGATGAGTACCTATTCAACAAACAGAACTATGATACGGATTCTGTTTGCTTTTGTATCATCAGTGG
CAAGAAACGACACCGGATACTACACTTGTTCCTCTTCAAAGCATCCCAGTCAATCAGCTTTGGTTACCATCGTAGAAAAGGGATTTATAA
ATGCTACCAATTCAAGTGAAGATTATGAAATTGACCAATATGAAGAGTTTTGTTTTTCTGTCAGGTTTAAAGCCTACCCACAAATCAGAT
GTACGTGGACCTTCTCTCGAAAATCATTTCCTTGTGAGCAAAAGGGTCTTGATAACGGATACAGCATATCCAAGTTTTGCAATCATAAGC
ACCAGCCAGGAGAATATATATTCCATGCAGAAAATGATGATGCCCAATTTACCAAAATGTTCACGCTGAATATAAGAAGGAAACCTCAAG
TGCTCGCAGAAGCATCGGCAAGTCAGGCGTCCTGTTTCTCGGATGGATACCCATTACCATCTTGGACCTGGAAGAAGTGTTCAGACAAGT
CTCCCAACTGCACAGAAGAGATCACAGAAGGAGTCTGGAATAGAAAGGCTAACAGAAAAGTGTTTGGACAGTGGGTGTCGAGCAGTACTC
TAAACATGAGTGAAGCCATAAAAGGGTTCCTGGTCAAGTGCTGTGCATACAATTCCCTTGGCACATCTTGTGAGACGATCCTTTTAAACT
CTCCAGGCCCCTTCCCTTTCATCCAAGACAACATCTCATTCTATGCAACAATTGGTGTTTGTCTCCTCTTCATTGTCGTTTTAACCCTGC
TAATTTGTCACAAGTACAAAAAGCAATTTAGGTATGAAAGCCAGCTACAGATGGTACAGGTGACCGGCTCCTCAGATAATGAGTACTTCT
ACGTTGATTTCAGAGAATATGAATATGATCTCAAATGGGAGTTTCCAAGAGAAAATTTAGAGTTTGGGAAGGTACTAGGATCAGGTGCTT
TTGGAAAAGTGATGAACGCAACAGCTTATGGAATTAGCAAAACAGGAGTCTCAATCCAGGTTGCCGTCAAAATGCTGAAAGAAAAAGCAG
ACAGCTCTGAAAGAGAGGCACTCATGTCAGAACTCAAGATGATGACCCAGCTGGGAAGCCACGAGAATATTGTGAACCTGCTGGGGGCGT
GCACACTGTCAGGACCAATTTACTTGATTTTTGAATACTGTTGCTATGGTGATCTTCTCAACTATCTAAGAAGTAAAAGAGAAAAATTTC
ACAGGACTTGGACAGAGATTTTCAAGGAACACAATTTCAGTTTTTACCCCACTTTCCAATCACATCCAAATTCCAGCATGCCTGGTTCAA
GAGAAGTTCAGATACACCCGGACTCGGATCAAATCTCAGGGCTTCATGGGAATTCATTTCACTCTGAAGATGAAATTGAATATGAAAACC
AAAAAAGGCTGGAAGAAGAGGAGGACTTGAATGTGCTTACATTTGAAGATCTTCTTTGCTTTGCATATCAAGTTGCCAAAGGAATGGAAT
TTCTGGAATTTAAGTCGTGTGTTCACAGAGACCTGGCCGCCAGGAACGTGCTTGTCACCCACGGGAAAGTGGTGAAGATATGTGACTTTG
GATTGGCTCGAGATATCATGAGTGATTCCAACTATGTTGTCAGGGGCAATGCCCGTCTGCCTGTAAAATGGATGGCCCCCGAAAGCCTGT
TTGAAGGCATCTACACCATTAAGAGTGATGTCTGGTCATATGGAATATTACTGTGGGAAATCTTCTCACTTGGTGTGAATCCTTACCCTG
GCATTCCGGTTGATGCTAACTTCTACAAACTGATTCAAAATGGATTTAAAATGGATCAGCCATTTTATGCTACAGAAGAAATATACATTA
TAATGCAATCCTGCTGGGCTTTTGACTCAAGGAAACGGCCATCCTTCCCTAATTTGACTTCGTTTTTAGGATGTCAGCTGGCAGATGCAG
AAGAAGCGATGTATCAGAATGTGGATGGCCGTGTTTCGGAATGTCCTCACACCTACCAAAACAGGCGACCTTTCAGCAGAGAGATGGATT
TGGGGCTACTCTCTCCGCAGGCTCAGGTCGAAGATTCGTAGAGGAACAATTTAGTTTTAAGGACTTCATCCCTCCACCTATCCCTAACAG
GCTGTAGATTACCAAAACAAGATTAATTTCATCACTAAAAGAAAATCTATTATCAACTGCTGCTTCACCAGACTTTTCTCTAGAAGCTGT
CTGCGTTTACTCTTGTTTTCAAAGGGACTTTTGTAAAATCAAATCATCCTGTCACAAGGCAGGAGGAGCTGATAATGAACTTTATTGGAG
CATTGATCTGCATCCAAGGCCTTCTCAGGCTGGCTTGAGTGAATTGTGTACCTGAAGTACAGTATATTCTTGTAAATACATAAAACAAAA
GCATTTTGCTAAGGAGAAGCTAATATGATTTTTTAAGTCTATGTTTTAAAATAATATGTAAATTTTTCAGCTATTTAGTGATATATTTTA
TGGGTGGGAATAAAATTTCTACTACAGAATTGCCCATTATTGAATTATTTACATGGTATAATTAGGGCAAGTCTTAACTGGAGTTCACGA
ACCCCCTGAAATTGTGCACCCATAGCCACCTACACATTCCTTCCAGAGCACGTGTGCTTTTACCCCAAGATACAAGGAATGTGTAGGCAG
CTATGGTTGTCACAGCCTAAGATTTCTGCAACAACAGGGGTTGTATTGGGGGAAGTTTATAATGAATAGGTGTTCTACCATAAAGAGTAA
TACATCACCTAGACACTTTGGCGGCCTTCCCAGACTCAGGGCCAGTCAGAAGTAACATGGAGGATTAGTATTTTCAATAAAGTTACTCTT

>62518_62518_1_PAN3-FLT3_PAN3_chr13_28794515_ENST00000380958_FLT3_chr13_28644749_ENST00000241453_length(amino acids)=1312AA_BP=333
MNSGGGLPPPSAAASPSSSSLAAAVAVVAPPGVGGVPGGAAVGVKLKYCRYYAKDKTCFYGEECQFLHEDPAAGAAPGLGLHSNSVPLAL
AGAPVAGFPPGAVAGGGAGPPPGPKKPDLGDPGTGAAAGGGGSSGGLDGPRLAIPGMDGGALTDTSLTDSYFSTSFIGVNGFGSPVETKY
PLMQRMTNSSSSPSLLNDSAKPYSAHDPLTSPASSLFNDFGALNISQRRKPRKYRLGMLEERLVPMGSKARKAKNPIGCLADRCKSGVPI
NMVWWNRVTENNLQTPNPTASEFIPKGGSTSRLSNVSQSNMSAFSQVFSHPSMGSPATAGLAPVVFSAMIFGTITNQDLPVIKCVLINHK
NNDSSVGKSSSYPMVSESPEDLGCALRPQSSGTVYEAAAVEVDVSASITLQVLVDAPGNISCLWVFKHSSLNCQPHFDLQNRGVVSMVIL
KMTETQAGEYLLFIQSEATNYTILFTVSIRNTLLYTLRRPYFRKMENQDALVCISESVPEPIVEWVLCDSQGESCKEESPAVVKKEEKVL
HELFGTDIRCCARNELGRECTRLFTIDLNQTPQTTLPQLFLKVGEPLWIRCKAVHVNHGFGLTWELENKALEEGNYFEMSTYSTNRTMIR
ILFAFVSSVARNDTGYYTCSSSKHPSQSALVTIVEKGFINATNSSEDYEIDQYEEFCFSVRFKAYPQIRCTWTFSRKSFPCEQKGLDNGY
SISKFCNHKHQPGEYIFHAENDDAQFTKMFTLNIRRKPQVLAEASASQASCFSDGYPLPSWTWKKCSDKSPNCTEEITEGVWNRKANRKV
FGQWVSSSTLNMSEAIKGFLVKCCAYNSLGTSCETILLNSPGPFPFIQDNISFYATIGVCLLFIVVLTLLICHKYKKQFRYESQLQMVQV
TGSSDNEYFYVDFREYEYDLKWEFPRENLEFGKVLGSGAFGKVMNATAYGISKTGVSIQVAVKMLKEKADSSEREALMSELKMMTQLGSH
ENIVNLLGACTLSGPIYLIFEYCCYGDLLNYLRSKREKFHRTWTEIFKEHNFSFYPTFQSHPNSSMPGSREVQIHPDSDQISGLHGNSFH
SEDEIEYENQKRLEEEEDLNVLTFEDLLCFAYQVAKGMEFLEFKSCVHRDLAARNVLVTHGKVVKICDFGLARDIMSDSNYVVRGNARLP
VKWMAPESLFEGIYTIKSDVWSYGILLWEIFSLGVNPYPGIPVDANFYKLIQNGFKMDQPFYATEEIYIIMQSCWAFDSRKRPSFPNLTS

--------------------------------------------------------------
>62518_62518_2_PAN3-FLT3_PAN3_chr13_28794515_ENST00000380958_FLT3_chr13_28644749_ENST00000380982_length(transcript)=4875nt_BP=1152nt
CTCCCCGGGCGGCTCCGGCTCCCGCAGCGGGACAGACCCACCCGCCCAGGCTTTTATCCGGCACCGGCAGCGTCTTCCTTTCCTCCCCCG
TCTATGGTGGTGGCGGCGGCGGCTCCTCGGGCGGCGGCGGAAGACGAGGCTGCGGCGTTGCCATGAACAGTGGCGGCGGCCTCCCGCCCC
CCTCGGCCGCCGCCTCCCCTTCCTCCTCCTCGCTGGCGGCGGCGGTGGCGGTGGTGGCCCCGCCGGGGGTCGGGGGTGTCCCCGGCGGGG
CGGCGGTAGGAGTGAAGCTGAAGTACTGCCGCTACTACGCTAAGGATAAGACTTGCTTCTACGGGGAGGAGTGTCAGTTCCTGCATGAGG
ACCCTGCCGCCGGGGCTGCCCCGGGCCTCGGCCTCCATAGCAACAGCGTCCCCCTGGCTCTGGCTGGTGCACCCGTGGCCGGCTTTCCGC
CGGGAGCCGTCGCGGGCGGGGGAGCTGGGCCGCCCCCCGGGCCCAAGAAGCCGGACCTGGGGGACCCGGGGACCGGAGCCGCAGCCGGCG
GAGGAGGCAGTAGCGGGGGACTCGATGGACCGCGGCTGGCAATTCCAGGAATGGATGGAGGTGCTTTAACTGATACAAGTCTCACAGATT
CCTATTTTAGCACCAGCTTTATTGGAGTCAATGGATTTGGAAGCCCTGTAGAAACAAAATATCCCCTGATGCAGAGAATGACTAATAGTA
GCAGCTCCCCAAGCCTTCTAAATGACAGTGCCAAGCCATATTCAGCCCATGATCCTCTAACATCACCTGCTTCATCCTTGTTTAATGACT
TTGGTGCCCTCAACATCTCTCAGAGACGAAAGCCAAGGAAGTATCGCCTGGGGATGCTGGAGGAGAGGCTAGTTCCGATGGGATCAAAGG
CACGAAAAGCAAAGAACCCTATTGGCTGCCTTGCTGACAGGTGTAAATCAGGAGTACCCATCAATATGGTTTGGTGGAACAGAGTCACAG
AAAACAATTTACAGACACCAAATCCTACTGCAAGCGAGTTTATTCCTAAAGGAGGATCAACCTCCAGGCTGAGTAACGTGTCCCAGTCAA
ATATGTCTGCCTTCTCTCAAGTTTTCTCTCACCCATCCATGGGAAGCCCTGCTACTGCTGGATTAGCGCCAGTTGTTTTTTCTGCAATGA
TATTTGGGACTATTACAAATCAAGATCTGCCTGTGATCAAGTGTGTTTTAATCAATCATAAGAACAATGATTCATCAGTGGGGAAGTCAT
CATCATATCCCATGGTATCAGAATCCCCGGAAGACCTCGGGTGTGCGTTGAGACCCCAGAGCTCAGGGACAGTGTACGAAGCTGCCGCTG
TGGAAGTGGATGTATCTGCTTCCATCACACTGCAAGTGCTGGTCGACGCCCCAGGGAACATTTCCTGTCTCTGGGTCTTTAAGCACAGCT
CCCTGAATTGCCAGCCACATTTTGATTTACAAAACAGAGGAGTTGTTTCCATGGTCATTTTGAAAATGACAGAAACCCAAGCTGGAGAAT
ACCTACTTTTTATTCAGAGTGAAGCTACCAATTACACAATATTGTTTACAGTGAGTATAAGAAATACCCTGCTTTACACATTAAGAAGAC
CTTACTTTAGAAAAATGGAAAACCAGGACGCCCTGGTCTGCATATCTGAGAGCGTTCCAGAGCCGATCGTGGAATGGGTGCTTTGCGATT
CACAGGGGGAAAGCTGTAAAGAAGAAAGTCCAGCTGTTGTTAAAAAGGAGGAAAAAGTGCTTCATGAATTATTTGGGACGGACATAAGGT
GCTGTGCCAGAAATGAACTGGGCAGGGAATGCACCAGGCTGTTCACAATAGATCTAAATCAAACTCCTCAGACCACATTGCCACAATTAT
TTCTTAAAGTAGGGGAACCCTTATGGATAAGGTGCAAAGCTGTTCATGTGAACCATGGATTCGGGCTCACCTGGGAATTAGAAAACAAAG
CACTCGAGGAGGGCAACTACTTTGAGATGAGTACCTATTCAACAAACAGAACTATGATACGGATTCTGTTTGCTTTTGTATCATCAGTGG
CAAGAAACGACACCGGATACTACACTTGTTCCTCTTCAAAGCATCCCAGTCAATCAGCTTTGGTTACCATCGTAGAAAAGGGATTTATAA
ATGCTACCAATTCAAGTGAAGATTATGAAATTGACCAATATGAAGAGTTTTGTTTTTCTGTCAGGTTTAAAGCCTACCCACAAATCAGAT
GTACGTGGACCTTCTCTCGAAAATCATTTCCTTGTGAGCAAAAGGGTCTTGATAACGGATACAGCATATCCAAGTTTTGCAATCATAAGC
ACCAGCCAGGAGAATATATATTCCATGCAGAAAATGATGATGCCCAATTTACCAAAATGTTCACGCTGAATATAAGAAGGAAACCTCAAG
TGCTCGCAGAAGCATCGGCAAGTCAGGCGTCCTGTTTCTCGGATGGATACCCATTACCATCTTGGACCTGGAAGAAGTGTTCAGACAAGT
CTCCCAACTGCACAGAAGAGATCACAGAAGGAGTCTGGAATAGAAAGGCTAACAGAAAAGTGTTTGGACAGTGGGTGTCGAGCAGTACTC
TAAACATGAGTGAAGCCATAAAAGGGTTCCTGGTCAAGTGCTGTGCATACAATTCCCTTGGCACATCTTGTGAGACGATCCTTTTAAACT
CTCCAGGCCCCTTCCCTTTCATCCAAGACAACATCTCATTCTATGCAACAATTGGTGTTTGTCTCCTCTTCATTGTCGTTTTAACCCTGC
TAATTTGTCACAAGTACAAAAAGCAATTTAGGTATGAAAGCCAGCTACAGATGGTACAGGTGACCGGCTCCTCAGATAATGAGTACTTCT
ACGTTGATTTCAGAGAATATGAATATGATCTCAAATGGGAGTTTCCAAGAGAAAATTTAGAGTTTGGGAAGGTACTAGGATCAGGTGCTT
TTGGAAAAGTGATGAACGCAACAGCTTATGGAATTAGCAAAACAGGAGTCTCAATCCAGGTTGCCGTCAAAATGCTGAAAGAAAAAGCAG
ACAGCTCTGAAAGAGAGGCACTCATGTCAGAACTCAAGATGATGACCCAGCTGGGAAGCCACGAGAATATTGTGAACCTGCTGGGGGCGT
GCACACTGTCAGGACCAATTTACTTGATTTTTGAATACTGTTGCTATGGTGATCTTCTCAACTATCTAAGAAGTAAAAGAGAAAAATTTC
ACAGGACTTGGACAGAGATTTTCAAGGAACACAATTTCAGTTTTTACCCCACTTTCCAATCACATCCAAATTCCAGCATGCCTGGTTCAA
GAGAAGTTCAGATACACCCGGACTCGGATCAAATCTCAGGGCTTCATGGGAATTCATTTCACTCTGAAGATGAAATTGAATATGAAAACC
AAAAAAGGCTGGAAGAAGAGGAGGACTTGAATGTGCTTACATTTGAAGATCTTCTTTGCTTTGCATATCAAGTTGCCAAAGGAATGGAAT
TTCTGGAATTTAAGTCGTGTGTTCACAGAGACCTGGCCGCCAGGAACGTGCTTGTCACCCACGGGAAAGTGGTGAAGATATGTGACTTTG
GATTGGCTCGAGATATCATGAGTGATTCCAACTATGTTGTCAGGGGCAATGTGAGGCTGGCCCGTCTGCCTGTAAAATGGATGGCCCCCG
AAAGCCTGTTTGAAGGCATCTACACCATTAAGAGTGATGTCTGGTCATATGGAATATTACTGTGGGAAATCTTCTCACTTGGTGTGAATC
CTTACCCTGGCATTCCGGTTGATGCTAACTTCTACAAACTGATTCAAAATGGATTTAAAATGGATCAGCCATTTTATGCTACAGAAGAAA
TATACATTATAATGCAATCCTGCTGGGCTTTTGACTCAAGGAAACGGCCATCCTTCCCTAATTTGACTTCGTTTTTAGGATGTCAGCTGG
CAGATGCAGAAGAAGCGATGTATCAGAATGTGGATGGCCGTGTTTCGGAATGTCCTCACACCTACCAAAACAGGCGACCTTTCAGCAGAG
AGATGGATTTGGGGCTACTCTCTCCGCAGGCTCAGGTCGAAGATTCGTAGAGGAACAATTTAGTTTTAAGGACTTCATCCCTCCACCTAT
CCCTAACAGGCTGTAGATTACCAAAACAAGATTAATTTCATCACTAAAAGAAAATCTATTATCAACTGCTGCTTCACCAGACTTTTCTCT
AGAAGCTGTCTGCGTTTACTCTTGTTTTCAAAGGGACTTTTGTAAAATCAAATCATCCTGTCACAAGGCAGGAGGAGCTGATAATGAACT
TTATTGGAGCATTGATCTGCATCCAAGGCCTTCTCAGGCTGGCTTGAGTGAATTGTGTACCTGAAGTACAGTATATTCTTGTAAATACAT
AAAACAAAAGCATTTTGCTAAGGAGAAGCTAATATGATTTTTTAAGTCTATGTTTTAAAATAATATGTAAATTTTTCAGCTATTTAGTGA
TATATTTTATGGGTGGGAATAAAATTTCTACTACAGAATTGCCCATTATTGAATTATTTACATGGTATAATTAGGGCAAGTCTTAACTGG
AGTTCACGAACCCCCTGAAATTGTGCACCCATAGCCACCTACACATTCCTTCCAGAGCACGTGTGCTTTTACCCCAAGATACAAGGAATG
TGTAGGCAGCTATGGTTGTCACAGCCTAAGATTTCTGCAACAACAGGGGTTGTATTGGGGGAAGTTTATAATGAATAGGTGTTCTACCAT
AAAGAGTAATACATCACCTAGACACTTTGGCGGCCTTCCCAGACTCAGGGCCAGTCAGAAGTAACATGGAGGATTAGTATTTTCAATAAA

>62518_62518_2_PAN3-FLT3_PAN3_chr13_28794515_ENST00000380958_FLT3_chr13_28644749_ENST00000380982_length(amino acids)=1315AA_BP=333
MNSGGGLPPPSAAASPSSSSLAAAVAVVAPPGVGGVPGGAAVGVKLKYCRYYAKDKTCFYGEECQFLHEDPAAGAAPGLGLHSNSVPLAL
AGAPVAGFPPGAVAGGGAGPPPGPKKPDLGDPGTGAAAGGGGSSGGLDGPRLAIPGMDGGALTDTSLTDSYFSTSFIGVNGFGSPVETKY
PLMQRMTNSSSSPSLLNDSAKPYSAHDPLTSPASSLFNDFGALNISQRRKPRKYRLGMLEERLVPMGSKARKAKNPIGCLADRCKSGVPI
NMVWWNRVTENNLQTPNPTASEFIPKGGSTSRLSNVSQSNMSAFSQVFSHPSMGSPATAGLAPVVFSAMIFGTITNQDLPVIKCVLINHK
NNDSSVGKSSSYPMVSESPEDLGCALRPQSSGTVYEAAAVEVDVSASITLQVLVDAPGNISCLWVFKHSSLNCQPHFDLQNRGVVSMVIL
KMTETQAGEYLLFIQSEATNYTILFTVSIRNTLLYTLRRPYFRKMENQDALVCISESVPEPIVEWVLCDSQGESCKEESPAVVKKEEKVL
HELFGTDIRCCARNELGRECTRLFTIDLNQTPQTTLPQLFLKVGEPLWIRCKAVHVNHGFGLTWELENKALEEGNYFEMSTYSTNRTMIR
ILFAFVSSVARNDTGYYTCSSSKHPSQSALVTIVEKGFINATNSSEDYEIDQYEEFCFSVRFKAYPQIRCTWTFSRKSFPCEQKGLDNGY
SISKFCNHKHQPGEYIFHAENDDAQFTKMFTLNIRRKPQVLAEASASQASCFSDGYPLPSWTWKKCSDKSPNCTEEITEGVWNRKANRKV
FGQWVSSSTLNMSEAIKGFLVKCCAYNSLGTSCETILLNSPGPFPFIQDNISFYATIGVCLLFIVVLTLLICHKYKKQFRYESQLQMVQV
TGSSDNEYFYVDFREYEYDLKWEFPRENLEFGKVLGSGAFGKVMNATAYGISKTGVSIQVAVKMLKEKADSSEREALMSELKMMTQLGSH
ENIVNLLGACTLSGPIYLIFEYCCYGDLLNYLRSKREKFHRTWTEIFKEHNFSFYPTFQSHPNSSMPGSREVQIHPDSDQISGLHGNSFH
SEDEIEYENQKRLEEEEDLNVLTFEDLLCFAYQVAKGMEFLEFKSCVHRDLAARNVLVTHGKVVKICDFGLARDIMSDSNYVVRGNVRLA
RLPVKWMAPESLFEGIYTIKSDVWSYGILLWEIFSLGVNPYPGIPVDANFYKLIQNGFKMDQPFYATEEIYIIMQSCWAFDSRKRPSFPN

--------------------------------------------------------------
>62518_62518_3_PAN3-FLT3_PAN3_chr13_28794515_ENST00000380958_FLT3_chr13_28644749_ENST00000537084_length(transcript)=4227nt_BP=1152nt
CTCCCCGGGCGGCTCCGGCTCCCGCAGCGGGACAGACCCACCCGCCCAGGCTTTTATCCGGCACCGGCAGCGTCTTCCTTTCCTCCCCCG
TCTATGGTGGTGGCGGCGGCGGCTCCTCGGGCGGCGGCGGAAGACGAGGCTGCGGCGTTGCCATGAACAGTGGCGGCGGCCTCCCGCCCC
CCTCGGCCGCCGCCTCCCCTTCCTCCTCCTCGCTGGCGGCGGCGGTGGCGGTGGTGGCCCCGCCGGGGGTCGGGGGTGTCCCCGGCGGGG
CGGCGGTAGGAGTGAAGCTGAAGTACTGCCGCTACTACGCTAAGGATAAGACTTGCTTCTACGGGGAGGAGTGTCAGTTCCTGCATGAGG
ACCCTGCCGCCGGGGCTGCCCCGGGCCTCGGCCTCCATAGCAACAGCGTCCCCCTGGCTCTGGCTGGTGCACCCGTGGCCGGCTTTCCGC
CGGGAGCCGTCGCGGGCGGGGGAGCTGGGCCGCCCCCCGGGCCCAAGAAGCCGGACCTGGGGGACCCGGGGACCGGAGCCGCAGCCGGCG
GAGGAGGCAGTAGCGGGGGACTCGATGGACCGCGGCTGGCAATTCCAGGAATGGATGGAGGTGCTTTAACTGATACAAGTCTCACAGATT
CCTATTTTAGCACCAGCTTTATTGGAGTCAATGGATTTGGAAGCCCTGTAGAAACAAAATATCCCCTGATGCAGAGAATGACTAATAGTA
GCAGCTCCCCAAGCCTTCTAAATGACAGTGCCAAGCCATATTCAGCCCATGATCCTCTAACATCACCTGCTTCATCCTTGTTTAATGACT
TTGGTGCCCTCAACATCTCTCAGAGACGAAAGCCAAGGAAGTATCGCCTGGGGATGCTGGAGGAGAGGCTAGTTCCGATGGGATCAAAGG
CACGAAAAGCAAAGAACCCTATTGGCTGCCTTGCTGACAGGTGTAAATCAGGAGTACCCATCAATATGGTTTGGTGGAACAGAGTCACAG
AAAACAATTTACAGACACCAAATCCTACTGCAAGCGAGTTTATTCCTAAAGGAGGATCAACCTCCAGGCTGAGTAACGTGTCCCAGTCAA
ATATGTCTGCCTTCTCTCAAGTTTTCTCTCACCCATCCATGGGAAGCCCTGCTACTGCTGGATTAGCGCCAGTTGTTTTTTCTGCAATGA
TATTTGGGACTATTACAAATCAAGATCTGCCTGTGATCAAGTGTGTTTTAATCAATCATAAGAACAATGATTCATCAGTGGGGAAGTCAT
CATCATATCCCATGGTATCAGAATCCCCGGAAGACCTCGGGTGTGCGTTGAGACCCCAGAGCTCAGGGACAGTGTACGAAGCTGCCGCTG
TGGAAGTGGATGTATCTGCTTCCATCACACTGCAAGTGCTGGTCGACGCCCCAGGGAACATTTCCTGTCTCTGGGTCTTTAAGCACAGCT
CCCTGAATTGCCAGCCACATTTTGATTTACAAAACAGAGGAGTTGTTTCCATGGTCATTTTGAAAATGACAGAAACCCAAGCTGGAGAAT
ACCTACTTTTTATTCAGAGTGAAGCTACCAATTACACAATATTGTTTACAGTGAGTATAAGAAATACCCTGCTTTACACATTAAGAAGAC
CTTACTTTAGAAAAATGGAAAACCAGGACGCCCTGGTCTGCATATCTGAGAGCGTTCCAGAGCCGATCGTGGAATGGGTGCTTTGCGATT
CACAGGGGGAAAGCTGTAAAGAAGAAAGTCCAGCTGTTGTTAAAAAGGAGGAAAAAGTGCTTCATGAATTATTTGGGACGGACATAAGGT
GCTGTGCCAGAAATGAACTGGGCAGGGAATGCACCAGGCTGTTCACAATAGATCTAAATCAAACTCCTCAGACCACATTGCCACAATTAT
TTCTTAAAGTAGGGGAACCCTTATGGATAAGGTGCAAAGCTGTTCATGTGAACCATGGATTCGGGCTCACCTGGGAATTAGAAAACAAAG
CACTCGAGGAGGGCAACTACTTTGAGATGAGTACCTATTCAACAAACAGAACTATGATACGGATTCTGTTTGCTTTTGTATCATCAGTGG
CAAGAAACGACACCGGATACTACACTTGTTCCTCTTCAAAGCATCCCAGTCAATCAGCTTTGGTTACCATCGTAGAAAAGGGATTTATAA
ATGCTACCAATTCAAGTGAAGATTATGAAATTGACCAATATGAAGAGTTTTGTTTTTCTGTCAGGTTTAAAGCCTACCCACAAATCAGAT
GTACGTGGACCTTCTCTCGAAAATCATTTCCTTGTGAGCAAAAGGGTCTTGATAACGGATACAGCATATCCAAGTTTTGCAATCATAAGC
ACCAGCCAGGAGAATATATATTCCATGCAGAAAATGATGATGCCCAATTTACCAAAATGTTCACGCTGAATATAAGAAGGAAACCTCAAG
TGCTCGCAGAAGCATCGGCAAGTCAGGCGTCCTGTTTCTCGGATGGATACCCATTACCATCTTGGACCTGGAAGAAGTGTTCAGACAAGT
CTCCCAACTGCACAGAAGAGATCACAGAAGGAGTCTGGAATAGAAAGGCTAACAGAAAAGTGTTTGGACAGTGGGTGTCGAGCAGTACTC
TAAACATGAGTGAAGCCATAAAAGGGTTCCTGGTCAAGTGCTGTGCATACAATTCCCTTGGCACATCTTGTGAGACGATCCTTTTAAACT
CTCCAGGCCCCTTCCCTTTCATCCAAGACAACATCTCATTCTATGCAACAATTGGTGTTTGTCTCCTCTTCATTGTCGTTTTAACCCTGC
TAATTTGTCACAAGTACAAAAAGCAATTTAGGTATGAAAGCCAGCTACAGATGGTACAGGTGACCGGCTCCTCAGATAATGAGTACTTCT
ACGTTGATTTCAGAGAATATGAATATGATCTCAAATGGGAGTTTCCAAGAGAAAATTTAGAGTTTGGGAAGGTACTAGGATCAGGTGCTT
TTGGAAAAGTGATGAACGCAACAGCTTATGGAATTAGCAAAACAGGAGTCTCAATCCAGGTTGCCGTCAAAATGCTGAAAGAAAAAGCAG
ACAGCTCTGAAAGAGAGGCACTCATGTCAGAACTCAAGATGATGACCCAGCTGGGAAGCCACGAGAATATTGTGAACCTGCTGGGGGCGT
GCACACTGTCAGGACCAATTTACTTGATTTTTGAATACTGTTGCTATGGTGATCTTCTCAACTATCTAAGAAGTAAAAGAGAAAAATTTC
ACAGGACTTGGACAGAGATTTTCAAGGAACACAATTTCAGTTTTTACCCCACTTTCCAATCACATCCAAATTCCAGCATGCCTGGTTCAA
GAGAAGTTCAGATACACCCGGACTCGGATCAAATCTCAGGGCTTCATGGGAATTCATTTCACTCTGAAGATGAAATTGAATATGAAAACC
AAAAAAGGCTGGAAGAAGAGGAGGACTTGAATGTGCTTACATTTGAAGATCTTCTTTGCTTTGCATATCAAGTTGCCAAAGGAATGGAAT
TTCTGGAATTTAAGTCGGCCCGTCTGCCTGTAAAATGGATGGCCCCCGAAAGCCTGTTTGAAGGCATCTACACCATTAAGAGTGATGTCT
GGTCATATGGAATATTACTGTGGGAAATCTTCTCACTTGGTGTGAATCCTTACCCTGGCATTCCGGTTGATGCTAACTTCTACAAACTGA
TTCAAAATGGATTTAAAATGGATCAGCCATTTTATGCTACAGAAGAAATATACATTATAATGCAATCCTGCTGGGCTTTTGACTCAAGGA
AACGGCCATCCTTCCCTAATTTGACTTCGTTTTTAGGATGTCAGCTGGCAGATGCAGAAGAAGCGATGTATCAGAATGTGGATGGCCGTG
TTTCGGAATGTCCTCACACCTACCAAAACAGGCGACCTTTCAGCAGAGAGATGGATTTGGGGCTACTCTCTCCGCAGGCTCAGGTCGAAG
ATTCGTAGAGGAACAATTTAGTTTTAAGGACTTCATCCCTCCACCTATCCCTAACAGGCTGTAGATTACCAAAACAAGATTAATTTCATC
ACTAAAAGAAAATCTATTATCAACTGCTGCTTCACCAGACTTTTCTCTAGAAGCTGTCTGCGTTTACTCTTGTTTTCAAAGGGACTTTTG

>62518_62518_3_PAN3-FLT3_PAN3_chr13_28794515_ENST00000380958_FLT3_chr13_28644749_ENST00000537084_length(amino acids)=1271AA_BP=333
MNSGGGLPPPSAAASPSSSSLAAAVAVVAPPGVGGVPGGAAVGVKLKYCRYYAKDKTCFYGEECQFLHEDPAAGAAPGLGLHSNSVPLAL
AGAPVAGFPPGAVAGGGAGPPPGPKKPDLGDPGTGAAAGGGGSSGGLDGPRLAIPGMDGGALTDTSLTDSYFSTSFIGVNGFGSPVETKY
PLMQRMTNSSSSPSLLNDSAKPYSAHDPLTSPASSLFNDFGALNISQRRKPRKYRLGMLEERLVPMGSKARKAKNPIGCLADRCKSGVPI
NMVWWNRVTENNLQTPNPTASEFIPKGGSTSRLSNVSQSNMSAFSQVFSHPSMGSPATAGLAPVVFSAMIFGTITNQDLPVIKCVLINHK
NNDSSVGKSSSYPMVSESPEDLGCALRPQSSGTVYEAAAVEVDVSASITLQVLVDAPGNISCLWVFKHSSLNCQPHFDLQNRGVVSMVIL
KMTETQAGEYLLFIQSEATNYTILFTVSIRNTLLYTLRRPYFRKMENQDALVCISESVPEPIVEWVLCDSQGESCKEESPAVVKKEEKVL
HELFGTDIRCCARNELGRECTRLFTIDLNQTPQTTLPQLFLKVGEPLWIRCKAVHVNHGFGLTWELENKALEEGNYFEMSTYSTNRTMIR
ILFAFVSSVARNDTGYYTCSSSKHPSQSALVTIVEKGFINATNSSEDYEIDQYEEFCFSVRFKAYPQIRCTWTFSRKSFPCEQKGLDNGY
SISKFCNHKHQPGEYIFHAENDDAQFTKMFTLNIRRKPQVLAEASASQASCFSDGYPLPSWTWKKCSDKSPNCTEEITEGVWNRKANRKV
FGQWVSSSTLNMSEAIKGFLVKCCAYNSLGTSCETILLNSPGPFPFIQDNISFYATIGVCLLFIVVLTLLICHKYKKQFRYESQLQMVQV
TGSSDNEYFYVDFREYEYDLKWEFPRENLEFGKVLGSGAFGKVMNATAYGISKTGVSIQVAVKMLKEKADSSEREALMSELKMMTQLGSH
ENIVNLLGACTLSGPIYLIFEYCCYGDLLNYLRSKREKFHRTWTEIFKEHNFSFYPTFQSHPNSSMPGSREVQIHPDSDQISGLHGNSFH
SEDEIEYENQKRLEEEEDLNVLTFEDLLCFAYQVAKGMEFLEFKSARLPVKWMAPESLFEGIYTIKSDVWSYGILLWEIFSLGVNPYPGI
PVDANFYKLIQNGFKMDQPFYATEEIYIIMQSCWAFDSRKRPSFPNLTSFLGCQLADAEEAMYQNVDGRVSECPHTYQNRRPFSREMDLG

--------------------------------------------------------------
>62518_62518_4_PAN3-FLT3_PAN3_chr13_28794515_ENST00000399613_FLT3_chr13_28644749_ENST00000241453_length(transcript)=4180nt_BP=463nt
GCCGCAGCCGGCGGAGGAGGCAGTAGCGGGGGACTCGATGGACCGCGGCTGGCAATTCCAGGAATGGATGGAGGTGCTTTAACTGATACA
AGTCTCACAGATTCCTATTTTAGCACCAGCTTTATTGGAGTCAATGGATTTGGAAGCCCTGTAGAAACAAAATATCCCCTGATGCAGAGA
ATGACTAATAGTAGCAGCTCCCCAAGCCTTCTAAATGACAGTGCCAAGCCATATTCAGCCCATGATCCTCTAACATCACCTGCTTCATCC
TTGTTTAATGACTTTGGTGCCCTCAACATCTCTCAGAGACGAAAGACACCAAATCCTACTGCAAGCGAGTTTATTCCTAAAGGAGGATCA
ACCTCCAGGCTGAGTAACGTGTCCCAGTCAAATATGTCTGCCTTCTCTCAAGTTTTCTCTCACCCATCCATGGGAAGCCCTGCTACTGCT
GGATTAGCGCCAGTTGTTTTTTCTGCAATGATATTTGGGACTATTACAAATCAAGATCTGCCTGTGATCAAGTGTGTTTTAATCAATCAT
AAGAACAATGATTCATCAGTGGGGAAGTCATCATCATATCCCATGGTATCAGAATCCCCGGAAGACCTCGGGTGTGCGTTGAGACCCCAG
AGCTCAGGGACAGTGTACGAAGCTGCCGCTGTGGAAGTGGATGTATCTGCTTCCATCACACTGCAAGTGCTGGTCGACGCCCCAGGGAAC
ATTTCCTGTCTCTGGGTCTTTAAGCACAGCTCCCTGAATTGCCAGCCACATTTTGATTTACAAAACAGAGGAGTTGTTTCCATGGTCATT
TTGAAAATGACAGAAACCCAAGCTGGAGAATACCTACTTTTTATTCAGAGTGAAGCTACCAATTACACAATATTGTTTACAGTGAGTATA
AGAAATACCCTGCTTTACACATTAAGAAGACCTTACTTTAGAAAAATGGAAAACCAGGACGCCCTGGTCTGCATATCTGAGAGCGTTCCA
GAGCCGATCGTGGAATGGGTGCTTTGCGATTCACAGGGGGAAAGCTGTAAAGAAGAAAGTCCAGCTGTTGTTAAAAAGGAGGAAAAAGTG
CTTCATGAATTATTTGGGACGGACATAAGGTGCTGTGCCAGAAATGAACTGGGCAGGGAATGCACCAGGCTGTTCACAATAGATCTAAAT
CAAACTCCTCAGACCACATTGCCACAATTATTTCTTAAAGTAGGGGAACCCTTATGGATAAGGTGCAAAGCTGTTCATGTGAACCATGGA
TTCGGGCTCACCTGGGAATTAGAAAACAAAGCACTCGAGGAGGGCAACTACTTTGAGATGAGTACCTATTCAACAAACAGAACTATGATA
CGGATTCTGTTTGCTTTTGTATCATCAGTGGCAAGAAACGACACCGGATACTACACTTGTTCCTCTTCAAAGCATCCCAGTCAATCAGCT
TTGGTTACCATCGTAGAAAAGGGATTTATAAATGCTACCAATTCAAGTGAAGATTATGAAATTGACCAATATGAAGAGTTTTGTTTTTCT
GTCAGGTTTAAAGCCTACCCACAAATCAGATGTACGTGGACCTTCTCTCGAAAATCATTTCCTTGTGAGCAAAAGGGTCTTGATAACGGA
TACAGCATATCCAAGTTTTGCAATCATAAGCACCAGCCAGGAGAATATATATTCCATGCAGAAAATGATGATGCCCAATTTACCAAAATG
TTCACGCTGAATATAAGAAGGAAACCTCAAGTGCTCGCAGAAGCATCGGCAAGTCAGGCGTCCTGTTTCTCGGATGGATACCCATTACCA
TCTTGGACCTGGAAGAAGTGTTCAGACAAGTCTCCCAACTGCACAGAAGAGATCACAGAAGGAGTCTGGAATAGAAAGGCTAACAGAAAA
GTGTTTGGACAGTGGGTGTCGAGCAGTACTCTAAACATGAGTGAAGCCATAAAAGGGTTCCTGGTCAAGTGCTGTGCATACAATTCCCTT
GGCACATCTTGTGAGACGATCCTTTTAAACTCTCCAGGCCCCTTCCCTTTCATCCAAGACAACATCTCATTCTATGCAACAATTGGTGTT
TGTCTCCTCTTCATTGTCGTTTTAACCCTGCTAATTTGTCACAAGTACAAAAAGCAATTTAGGTATGAAAGCCAGCTACAGATGGTACAG
GTGACCGGCTCCTCAGATAATGAGTACTTCTACGTTGATTTCAGAGAATATGAATATGATCTCAAATGGGAGTTTCCAAGAGAAAATTTA
GAGTTTGGGAAGGTACTAGGATCAGGTGCTTTTGGAAAAGTGATGAACGCAACAGCTTATGGAATTAGCAAAACAGGAGTCTCAATCCAG
GTTGCCGTCAAAATGCTGAAAGAAAAAGCAGACAGCTCTGAAAGAGAGGCACTCATGTCAGAACTCAAGATGATGACCCAGCTGGGAAGC
CACGAGAATATTGTGAACCTGCTGGGGGCGTGCACACTGTCAGGACCAATTTACTTGATTTTTGAATACTGTTGCTATGGTGATCTTCTC
AACTATCTAAGAAGTAAAAGAGAAAAATTTCACAGGACTTGGACAGAGATTTTCAAGGAACACAATTTCAGTTTTTACCCCACTTTCCAA
TCACATCCAAATTCCAGCATGCCTGGTTCAAGAGAAGTTCAGATACACCCGGACTCGGATCAAATCTCAGGGCTTCATGGGAATTCATTT
CACTCTGAAGATGAAATTGAATATGAAAACCAAAAAAGGCTGGAAGAAGAGGAGGACTTGAATGTGCTTACATTTGAAGATCTTCTTTGC
TTTGCATATCAAGTTGCCAAAGGAATGGAATTTCTGGAATTTAAGTCGTGTGTTCACAGAGACCTGGCCGCCAGGAACGTGCTTGTCACC
CACGGGAAAGTGGTGAAGATATGTGACTTTGGATTGGCTCGAGATATCATGAGTGATTCCAACTATGTTGTCAGGGGCAATGCCCGTCTG
CCTGTAAAATGGATGGCCCCCGAAAGCCTGTTTGAAGGCATCTACACCATTAAGAGTGATGTCTGGTCATATGGAATATTACTGTGGGAA
ATCTTCTCACTTGGTGTGAATCCTTACCCTGGCATTCCGGTTGATGCTAACTTCTACAAACTGATTCAAAATGGATTTAAAATGGATCAG
CCATTTTATGCTACAGAAGAAATATACATTATAATGCAATCCTGCTGGGCTTTTGACTCAAGGAAACGGCCATCCTTCCCTAATTTGACT
TCGTTTTTAGGATGTCAGCTGGCAGATGCAGAAGAAGCGATGTATCAGAATGTGGATGGCCGTGTTTCGGAATGTCCTCACACCTACCAA
AACAGGCGACCTTTCAGCAGAGAGATGGATTTGGGGCTACTCTCTCCGCAGGCTCAGGTCGAAGATTCGTAGAGGAACAATTTAGTTTTA
AGGACTTCATCCCTCCACCTATCCCTAACAGGCTGTAGATTACCAAAACAAGATTAATTTCATCACTAAAAGAAAATCTATTATCAACTG
CTGCTTCACCAGACTTTTCTCTAGAAGCTGTCTGCGTTTACTCTTGTTTTCAAAGGGACTTTTGTAAAATCAAATCATCCTGTCACAAGG
CAGGAGGAGCTGATAATGAACTTTATTGGAGCATTGATCTGCATCCAAGGCCTTCTCAGGCTGGCTTGAGTGAATTGTGTACCTGAAGTA
CAGTATATTCTTGTAAATACATAAAACAAAAGCATTTTGCTAAGGAGAAGCTAATATGATTTTTTAAGTCTATGTTTTAAAATAATATGT
AAATTTTTCAGCTATTTAGTGATATATTTTATGGGTGGGAATAAAATTTCTACTACAGAATTGCCCATTATTGAATTATTTACATGGTAT
AATTAGGGCAAGTCTTAACTGGAGTTCACGAACCCCCTGAAATTGTGCACCCATAGCCACCTACACATTCCTTCCAGAGCACGTGTGCTT
TTACCCCAAGATACAAGGAATGTGTAGGCAGCTATGGTTGTCACAGCCTAAGATTTCTGCAACAACAGGGGTTGTATTGGGGGAAGTTTA
TAATGAATAGGTGTTCTACCATAAAGAGTAATACATCACCTAGACACTTTGGCGGCCTTCCCAGACTCAGGGCCAGTCAGAAGTAACATG

>62518_62518_4_PAN3-FLT3_PAN3_chr13_28794515_ENST00000399613_FLT3_chr13_28644749_ENST00000241453_length(amino acids)=1117AA_BP=138
MAIPGMDGGALTDTSLTDSYFSTSFIGVNGFGSPVETKYPLMQRMTNSSSSPSLLNDSAKPYSAHDPLTSPASSLFNDFGALNISQRRKT
PNPTASEFIPKGGSTSRLSNVSQSNMSAFSQVFSHPSMGSPATAGLAPVVFSAMIFGTITNQDLPVIKCVLINHKNNDSSVGKSSSYPMV
SESPEDLGCALRPQSSGTVYEAAAVEVDVSASITLQVLVDAPGNISCLWVFKHSSLNCQPHFDLQNRGVVSMVILKMTETQAGEYLLFIQ
SEATNYTILFTVSIRNTLLYTLRRPYFRKMENQDALVCISESVPEPIVEWVLCDSQGESCKEESPAVVKKEEKVLHELFGTDIRCCARNE
LGRECTRLFTIDLNQTPQTTLPQLFLKVGEPLWIRCKAVHVNHGFGLTWELENKALEEGNYFEMSTYSTNRTMIRILFAFVSSVARNDTG
YYTCSSSKHPSQSALVTIVEKGFINATNSSEDYEIDQYEEFCFSVRFKAYPQIRCTWTFSRKSFPCEQKGLDNGYSISKFCNHKHQPGEY
IFHAENDDAQFTKMFTLNIRRKPQVLAEASASQASCFSDGYPLPSWTWKKCSDKSPNCTEEITEGVWNRKANRKVFGQWVSSSTLNMSEA
IKGFLVKCCAYNSLGTSCETILLNSPGPFPFIQDNISFYATIGVCLLFIVVLTLLICHKYKKQFRYESQLQMVQVTGSSDNEYFYVDFRE
YEYDLKWEFPRENLEFGKVLGSGAFGKVMNATAYGISKTGVSIQVAVKMLKEKADSSEREALMSELKMMTQLGSHENIVNLLGACTLSGP
IYLIFEYCCYGDLLNYLRSKREKFHRTWTEIFKEHNFSFYPTFQSHPNSSMPGSREVQIHPDSDQISGLHGNSFHSEDEIEYENQKRLEE
EEDLNVLTFEDLLCFAYQVAKGMEFLEFKSCVHRDLAARNVLVTHGKVVKICDFGLARDIMSDSNYVVRGNARLPVKWMAPESLFEGIYT
IKSDVWSYGILLWEIFSLGVNPYPGIPVDANFYKLIQNGFKMDQPFYATEEIYIIMQSCWAFDSRKRPSFPNLTSFLGCQLADAEEAMYQ

--------------------------------------------------------------
>62518_62518_5_PAN3-FLT3_PAN3_chr13_28794515_ENST00000399613_FLT3_chr13_28644749_ENST00000380982_length(transcript)=4186nt_BP=463nt
GCCGCAGCCGGCGGAGGAGGCAGTAGCGGGGGACTCGATGGACCGCGGCTGGCAATTCCAGGAATGGATGGAGGTGCTTTAACTGATACA
AGTCTCACAGATTCCTATTTTAGCACCAGCTTTATTGGAGTCAATGGATTTGGAAGCCCTGTAGAAACAAAATATCCCCTGATGCAGAGA
ATGACTAATAGTAGCAGCTCCCCAAGCCTTCTAAATGACAGTGCCAAGCCATATTCAGCCCATGATCCTCTAACATCACCTGCTTCATCC
TTGTTTAATGACTTTGGTGCCCTCAACATCTCTCAGAGACGAAAGACACCAAATCCTACTGCAAGCGAGTTTATTCCTAAAGGAGGATCA
ACCTCCAGGCTGAGTAACGTGTCCCAGTCAAATATGTCTGCCTTCTCTCAAGTTTTCTCTCACCCATCCATGGGAAGCCCTGCTACTGCT
GGATTAGCGCCAGTTGTTTTTTCTGCAATGATATTTGGGACTATTACAAATCAAGATCTGCCTGTGATCAAGTGTGTTTTAATCAATCAT
AAGAACAATGATTCATCAGTGGGGAAGTCATCATCATATCCCATGGTATCAGAATCCCCGGAAGACCTCGGGTGTGCGTTGAGACCCCAG
AGCTCAGGGACAGTGTACGAAGCTGCCGCTGTGGAAGTGGATGTATCTGCTTCCATCACACTGCAAGTGCTGGTCGACGCCCCAGGGAAC
ATTTCCTGTCTCTGGGTCTTTAAGCACAGCTCCCTGAATTGCCAGCCACATTTTGATTTACAAAACAGAGGAGTTGTTTCCATGGTCATT
TTGAAAATGACAGAAACCCAAGCTGGAGAATACCTACTTTTTATTCAGAGTGAAGCTACCAATTACACAATATTGTTTACAGTGAGTATA
AGAAATACCCTGCTTTACACATTAAGAAGACCTTACTTTAGAAAAATGGAAAACCAGGACGCCCTGGTCTGCATATCTGAGAGCGTTCCA
GAGCCGATCGTGGAATGGGTGCTTTGCGATTCACAGGGGGAAAGCTGTAAAGAAGAAAGTCCAGCTGTTGTTAAAAAGGAGGAAAAAGTG
CTTCATGAATTATTTGGGACGGACATAAGGTGCTGTGCCAGAAATGAACTGGGCAGGGAATGCACCAGGCTGTTCACAATAGATCTAAAT
CAAACTCCTCAGACCACATTGCCACAATTATTTCTTAAAGTAGGGGAACCCTTATGGATAAGGTGCAAAGCTGTTCATGTGAACCATGGA
TTCGGGCTCACCTGGGAATTAGAAAACAAAGCACTCGAGGAGGGCAACTACTTTGAGATGAGTACCTATTCAACAAACAGAACTATGATA
CGGATTCTGTTTGCTTTTGTATCATCAGTGGCAAGAAACGACACCGGATACTACACTTGTTCCTCTTCAAAGCATCCCAGTCAATCAGCT
TTGGTTACCATCGTAGAAAAGGGATTTATAAATGCTACCAATTCAAGTGAAGATTATGAAATTGACCAATATGAAGAGTTTTGTTTTTCT
GTCAGGTTTAAAGCCTACCCACAAATCAGATGTACGTGGACCTTCTCTCGAAAATCATTTCCTTGTGAGCAAAAGGGTCTTGATAACGGA
TACAGCATATCCAAGTTTTGCAATCATAAGCACCAGCCAGGAGAATATATATTCCATGCAGAAAATGATGATGCCCAATTTACCAAAATG
TTCACGCTGAATATAAGAAGGAAACCTCAAGTGCTCGCAGAAGCATCGGCAAGTCAGGCGTCCTGTTTCTCGGATGGATACCCATTACCA
TCTTGGACCTGGAAGAAGTGTTCAGACAAGTCTCCCAACTGCACAGAAGAGATCACAGAAGGAGTCTGGAATAGAAAGGCTAACAGAAAA
GTGTTTGGACAGTGGGTGTCGAGCAGTACTCTAAACATGAGTGAAGCCATAAAAGGGTTCCTGGTCAAGTGCTGTGCATACAATTCCCTT
GGCACATCTTGTGAGACGATCCTTTTAAACTCTCCAGGCCCCTTCCCTTTCATCCAAGACAACATCTCATTCTATGCAACAATTGGTGTT
TGTCTCCTCTTCATTGTCGTTTTAACCCTGCTAATTTGTCACAAGTACAAAAAGCAATTTAGGTATGAAAGCCAGCTACAGATGGTACAG
GTGACCGGCTCCTCAGATAATGAGTACTTCTACGTTGATTTCAGAGAATATGAATATGATCTCAAATGGGAGTTTCCAAGAGAAAATTTA
GAGTTTGGGAAGGTACTAGGATCAGGTGCTTTTGGAAAAGTGATGAACGCAACAGCTTATGGAATTAGCAAAACAGGAGTCTCAATCCAG
GTTGCCGTCAAAATGCTGAAAGAAAAAGCAGACAGCTCTGAAAGAGAGGCACTCATGTCAGAACTCAAGATGATGACCCAGCTGGGAAGC
CACGAGAATATTGTGAACCTGCTGGGGGCGTGCACACTGTCAGGACCAATTTACTTGATTTTTGAATACTGTTGCTATGGTGATCTTCTC
AACTATCTAAGAAGTAAAAGAGAAAAATTTCACAGGACTTGGACAGAGATTTTCAAGGAACACAATTTCAGTTTTTACCCCACTTTCCAA
TCACATCCAAATTCCAGCATGCCTGGTTCAAGAGAAGTTCAGATACACCCGGACTCGGATCAAATCTCAGGGCTTCATGGGAATTCATTT
CACTCTGAAGATGAAATTGAATATGAAAACCAAAAAAGGCTGGAAGAAGAGGAGGACTTGAATGTGCTTACATTTGAAGATCTTCTTTGC
TTTGCATATCAAGTTGCCAAAGGAATGGAATTTCTGGAATTTAAGTCGTGTGTTCACAGAGACCTGGCCGCCAGGAACGTGCTTGTCACC
CACGGGAAAGTGGTGAAGATATGTGACTTTGGATTGGCTCGAGATATCATGAGTGATTCCAACTATGTTGTCAGGGGCAATGTGAGGCTG
GCCCGTCTGCCTGTAAAATGGATGGCCCCCGAAAGCCTGTTTGAAGGCATCTACACCATTAAGAGTGATGTCTGGTCATATGGAATATTA
CTGTGGGAAATCTTCTCACTTGGTGTGAATCCTTACCCTGGCATTCCGGTTGATGCTAACTTCTACAAACTGATTCAAAATGGATTTAAA
ATGGATCAGCCATTTTATGCTACAGAAGAAATATACATTATAATGCAATCCTGCTGGGCTTTTGACTCAAGGAAACGGCCATCCTTCCCT
AATTTGACTTCGTTTTTAGGATGTCAGCTGGCAGATGCAGAAGAAGCGATGTATCAGAATGTGGATGGCCGTGTTTCGGAATGTCCTCAC
ACCTACCAAAACAGGCGACCTTTCAGCAGAGAGATGGATTTGGGGCTACTCTCTCCGCAGGCTCAGGTCGAAGATTCGTAGAGGAACAAT
TTAGTTTTAAGGACTTCATCCCTCCACCTATCCCTAACAGGCTGTAGATTACCAAAACAAGATTAATTTCATCACTAAAAGAAAATCTAT
TATCAACTGCTGCTTCACCAGACTTTTCTCTAGAAGCTGTCTGCGTTTACTCTTGTTTTCAAAGGGACTTTTGTAAAATCAAATCATCCT
GTCACAAGGCAGGAGGAGCTGATAATGAACTTTATTGGAGCATTGATCTGCATCCAAGGCCTTCTCAGGCTGGCTTGAGTGAATTGTGTA
CCTGAAGTACAGTATATTCTTGTAAATACATAAAACAAAAGCATTTTGCTAAGGAGAAGCTAATATGATTTTTTAAGTCTATGTTTTAAA
ATAATATGTAAATTTTTCAGCTATTTAGTGATATATTTTATGGGTGGGAATAAAATTTCTACTACAGAATTGCCCATTATTGAATTATTT
ACATGGTATAATTAGGGCAAGTCTTAACTGGAGTTCACGAACCCCCTGAAATTGTGCACCCATAGCCACCTACACATTCCTTCCAGAGCA
CGTGTGCTTTTACCCCAAGATACAAGGAATGTGTAGGCAGCTATGGTTGTCACAGCCTAAGATTTCTGCAACAACAGGGGTTGTATTGGG
GGAAGTTTATAATGAATAGGTGTTCTACCATAAAGAGTAATACATCACCTAGACACTTTGGCGGCCTTCCCAGACTCAGGGCCAGTCAGA

>62518_62518_5_PAN3-FLT3_PAN3_chr13_28794515_ENST00000399613_FLT3_chr13_28644749_ENST00000380982_length(amino acids)=1120AA_BP=138
MAIPGMDGGALTDTSLTDSYFSTSFIGVNGFGSPVETKYPLMQRMTNSSSSPSLLNDSAKPYSAHDPLTSPASSLFNDFGALNISQRRKT
PNPTASEFIPKGGSTSRLSNVSQSNMSAFSQVFSHPSMGSPATAGLAPVVFSAMIFGTITNQDLPVIKCVLINHKNNDSSVGKSSSYPMV
SESPEDLGCALRPQSSGTVYEAAAVEVDVSASITLQVLVDAPGNISCLWVFKHSSLNCQPHFDLQNRGVVSMVILKMTETQAGEYLLFIQ
SEATNYTILFTVSIRNTLLYTLRRPYFRKMENQDALVCISESVPEPIVEWVLCDSQGESCKEESPAVVKKEEKVLHELFGTDIRCCARNE
LGRECTRLFTIDLNQTPQTTLPQLFLKVGEPLWIRCKAVHVNHGFGLTWELENKALEEGNYFEMSTYSTNRTMIRILFAFVSSVARNDTG
YYTCSSSKHPSQSALVTIVEKGFINATNSSEDYEIDQYEEFCFSVRFKAYPQIRCTWTFSRKSFPCEQKGLDNGYSISKFCNHKHQPGEY
IFHAENDDAQFTKMFTLNIRRKPQVLAEASASQASCFSDGYPLPSWTWKKCSDKSPNCTEEITEGVWNRKANRKVFGQWVSSSTLNMSEA
IKGFLVKCCAYNSLGTSCETILLNSPGPFPFIQDNISFYATIGVCLLFIVVLTLLICHKYKKQFRYESQLQMVQVTGSSDNEYFYVDFRE
YEYDLKWEFPRENLEFGKVLGSGAFGKVMNATAYGISKTGVSIQVAVKMLKEKADSSEREALMSELKMMTQLGSHENIVNLLGACTLSGP
IYLIFEYCCYGDLLNYLRSKREKFHRTWTEIFKEHNFSFYPTFQSHPNSSMPGSREVQIHPDSDQISGLHGNSFHSEDEIEYENQKRLEE
EEDLNVLTFEDLLCFAYQVAKGMEFLEFKSCVHRDLAARNVLVTHGKVVKICDFGLARDIMSDSNYVVRGNVRLARLPVKWMAPESLFEG
IYTIKSDVWSYGILLWEIFSLGVNPYPGIPVDANFYKLIQNGFKMDQPFYATEEIYIIMQSCWAFDSRKRPSFPNLTSFLGCQLADAEEA

--------------------------------------------------------------
>62518_62518_6_PAN3-FLT3_PAN3_chr13_28794515_ENST00000399613_FLT3_chr13_28644749_ENST00000537084_length(transcript)=3538nt_BP=463nt
GCCGCAGCCGGCGGAGGAGGCAGTAGCGGGGGACTCGATGGACCGCGGCTGGCAATTCCAGGAATGGATGGAGGTGCTTTAACTGATACA
AGTCTCACAGATTCCTATTTTAGCACCAGCTTTATTGGAGTCAATGGATTTGGAAGCCCTGTAGAAACAAAATATCCCCTGATGCAGAGA
ATGACTAATAGTAGCAGCTCCCCAAGCCTTCTAAATGACAGTGCCAAGCCATATTCAGCCCATGATCCTCTAACATCACCTGCTTCATCC
TTGTTTAATGACTTTGGTGCCCTCAACATCTCTCAGAGACGAAAGACACCAAATCCTACTGCAAGCGAGTTTATTCCTAAAGGAGGATCA
ACCTCCAGGCTGAGTAACGTGTCCCAGTCAAATATGTCTGCCTTCTCTCAAGTTTTCTCTCACCCATCCATGGGAAGCCCTGCTACTGCT
GGATTAGCGCCAGTTGTTTTTTCTGCAATGATATTTGGGACTATTACAAATCAAGATCTGCCTGTGATCAAGTGTGTTTTAATCAATCAT
AAGAACAATGATTCATCAGTGGGGAAGTCATCATCATATCCCATGGTATCAGAATCCCCGGAAGACCTCGGGTGTGCGTTGAGACCCCAG
AGCTCAGGGACAGTGTACGAAGCTGCCGCTGTGGAAGTGGATGTATCTGCTTCCATCACACTGCAAGTGCTGGTCGACGCCCCAGGGAAC
ATTTCCTGTCTCTGGGTCTTTAAGCACAGCTCCCTGAATTGCCAGCCACATTTTGATTTACAAAACAGAGGAGTTGTTTCCATGGTCATT
TTGAAAATGACAGAAACCCAAGCTGGAGAATACCTACTTTTTATTCAGAGTGAAGCTACCAATTACACAATATTGTTTACAGTGAGTATA
AGAAATACCCTGCTTTACACATTAAGAAGACCTTACTTTAGAAAAATGGAAAACCAGGACGCCCTGGTCTGCATATCTGAGAGCGTTCCA
GAGCCGATCGTGGAATGGGTGCTTTGCGATTCACAGGGGGAAAGCTGTAAAGAAGAAAGTCCAGCTGTTGTTAAAAAGGAGGAAAAAGTG
CTTCATGAATTATTTGGGACGGACATAAGGTGCTGTGCCAGAAATGAACTGGGCAGGGAATGCACCAGGCTGTTCACAATAGATCTAAAT
CAAACTCCTCAGACCACATTGCCACAATTATTTCTTAAAGTAGGGGAACCCTTATGGATAAGGTGCAAAGCTGTTCATGTGAACCATGGA
TTCGGGCTCACCTGGGAATTAGAAAACAAAGCACTCGAGGAGGGCAACTACTTTGAGATGAGTACCTATTCAACAAACAGAACTATGATA
CGGATTCTGTTTGCTTTTGTATCATCAGTGGCAAGAAACGACACCGGATACTACACTTGTTCCTCTTCAAAGCATCCCAGTCAATCAGCT
TTGGTTACCATCGTAGAAAAGGGATTTATAAATGCTACCAATTCAAGTGAAGATTATGAAATTGACCAATATGAAGAGTTTTGTTTTTCT
GTCAGGTTTAAAGCCTACCCACAAATCAGATGTACGTGGACCTTCTCTCGAAAATCATTTCCTTGTGAGCAAAAGGGTCTTGATAACGGA
TACAGCATATCCAAGTTTTGCAATCATAAGCACCAGCCAGGAGAATATATATTCCATGCAGAAAATGATGATGCCCAATTTACCAAAATG
TTCACGCTGAATATAAGAAGGAAACCTCAAGTGCTCGCAGAAGCATCGGCAAGTCAGGCGTCCTGTTTCTCGGATGGATACCCATTACCA
TCTTGGACCTGGAAGAAGTGTTCAGACAAGTCTCCCAACTGCACAGAAGAGATCACAGAAGGAGTCTGGAATAGAAAGGCTAACAGAAAA
GTGTTTGGACAGTGGGTGTCGAGCAGTACTCTAAACATGAGTGAAGCCATAAAAGGGTTCCTGGTCAAGTGCTGTGCATACAATTCCCTT
GGCACATCTTGTGAGACGATCCTTTTAAACTCTCCAGGCCCCTTCCCTTTCATCCAAGACAACATCTCATTCTATGCAACAATTGGTGTT
TGTCTCCTCTTCATTGTCGTTTTAACCCTGCTAATTTGTCACAAGTACAAAAAGCAATTTAGGTATGAAAGCCAGCTACAGATGGTACAG
GTGACCGGCTCCTCAGATAATGAGTACTTCTACGTTGATTTCAGAGAATATGAATATGATCTCAAATGGGAGTTTCCAAGAGAAAATTTA
GAGTTTGGGAAGGTACTAGGATCAGGTGCTTTTGGAAAAGTGATGAACGCAACAGCTTATGGAATTAGCAAAACAGGAGTCTCAATCCAG
GTTGCCGTCAAAATGCTGAAAGAAAAAGCAGACAGCTCTGAAAGAGAGGCACTCATGTCAGAACTCAAGATGATGACCCAGCTGGGAAGC
CACGAGAATATTGTGAACCTGCTGGGGGCGTGCACACTGTCAGGACCAATTTACTTGATTTTTGAATACTGTTGCTATGGTGATCTTCTC
AACTATCTAAGAAGTAAAAGAGAAAAATTTCACAGGACTTGGACAGAGATTTTCAAGGAACACAATTTCAGTTTTTACCCCACTTTCCAA
TCACATCCAAATTCCAGCATGCCTGGTTCAAGAGAAGTTCAGATACACCCGGACTCGGATCAAATCTCAGGGCTTCATGGGAATTCATTT
CACTCTGAAGATGAAATTGAATATGAAAACCAAAAAAGGCTGGAAGAAGAGGAGGACTTGAATGTGCTTACATTTGAAGATCTTCTTTGC
TTTGCATATCAAGTTGCCAAAGGAATGGAATTTCTGGAATTTAAGTCGGCCCGTCTGCCTGTAAAATGGATGGCCCCCGAAAGCCTGTTT
GAAGGCATCTACACCATTAAGAGTGATGTCTGGTCATATGGAATATTACTGTGGGAAATCTTCTCACTTGGTGTGAATCCTTACCCTGGC
ATTCCGGTTGATGCTAACTTCTACAAACTGATTCAAAATGGATTTAAAATGGATCAGCCATTTTATGCTACAGAAGAAATATACATTATA
ATGCAATCCTGCTGGGCTTTTGACTCAAGGAAACGGCCATCCTTCCCTAATTTGACTTCGTTTTTAGGATGTCAGCTGGCAGATGCAGAA
GAAGCGATGTATCAGAATGTGGATGGCCGTGTTTCGGAATGTCCTCACACCTACCAAAACAGGCGACCTTTCAGCAGAGAGATGGATTTG
GGGCTACTCTCTCCGCAGGCTCAGGTCGAAGATTCGTAGAGGAACAATTTAGTTTTAAGGACTTCATCCCTCCACCTATCCCTAACAGGC
TGTAGATTACCAAAACAAGATTAATTTCATCACTAAAAGAAAATCTATTATCAACTGCTGCTTCACCAGACTTTTCTCTAGAAGCTGTCT
GCGTTTACTCTTGTTTTCAAAGGGACTTTTGTAAAATCAAATCATCCTGTCACAAGGCAGGAGGAGCTGATAATGAACTTTATTGGAGCA

>62518_62518_6_PAN3-FLT3_PAN3_chr13_28794515_ENST00000399613_FLT3_chr13_28644749_ENST00000537084_length(amino acids)=1076AA_BP=138
MAIPGMDGGALTDTSLTDSYFSTSFIGVNGFGSPVETKYPLMQRMTNSSSSPSLLNDSAKPYSAHDPLTSPASSLFNDFGALNISQRRKT
PNPTASEFIPKGGSTSRLSNVSQSNMSAFSQVFSHPSMGSPATAGLAPVVFSAMIFGTITNQDLPVIKCVLINHKNNDSSVGKSSSYPMV
SESPEDLGCALRPQSSGTVYEAAAVEVDVSASITLQVLVDAPGNISCLWVFKHSSLNCQPHFDLQNRGVVSMVILKMTETQAGEYLLFIQ
SEATNYTILFTVSIRNTLLYTLRRPYFRKMENQDALVCISESVPEPIVEWVLCDSQGESCKEESPAVVKKEEKVLHELFGTDIRCCARNE
LGRECTRLFTIDLNQTPQTTLPQLFLKVGEPLWIRCKAVHVNHGFGLTWELENKALEEGNYFEMSTYSTNRTMIRILFAFVSSVARNDTG
YYTCSSSKHPSQSALVTIVEKGFINATNSSEDYEIDQYEEFCFSVRFKAYPQIRCTWTFSRKSFPCEQKGLDNGYSISKFCNHKHQPGEY
IFHAENDDAQFTKMFTLNIRRKPQVLAEASASQASCFSDGYPLPSWTWKKCSDKSPNCTEEITEGVWNRKANRKVFGQWVSSSTLNMSEA
IKGFLVKCCAYNSLGTSCETILLNSPGPFPFIQDNISFYATIGVCLLFIVVLTLLICHKYKKQFRYESQLQMVQVTGSSDNEYFYVDFRE
YEYDLKWEFPRENLEFGKVLGSGAFGKVMNATAYGISKTGVSIQVAVKMLKEKADSSEREALMSELKMMTQLGSHENIVNLLGACTLSGP
IYLIFEYCCYGDLLNYLRSKREKFHRTWTEIFKEHNFSFYPTFQSHPNSSMPGSREVQIHPDSDQISGLHGNSFHSEDEIEYENQKRLEE
EEDLNVLTFEDLLCFAYQVAKGMEFLEFKSARLPVKWMAPESLFEGIYTIKSDVWSYGILLWEIFSLGVNPYPGIPVDANFYKLIQNGFK

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Fusion Gene PPI Analysis for PAN3-FLT3


check button Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in

ChiPPI page.


check button Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160)
HgeneHgene's interactorsTgeneTgene's interactors


check button - Retained PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenStill interaction with


check button - Lost PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


check button - Retained PPIs, but lost function due to frame-shift fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


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Related Drugs for PAN3-FLT3


check button Drugs targeting genes involved in this fusion gene.
(DrugBank Version 5.1.8 2021-05-08)
PartnerGeneUniProtAccDrugBank IDDrug nameDrug activityDrug typeDrug status

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Related Diseases for PAN3-FLT3


check button Diseases associated with fusion partners.
(DisGeNet 4.0)
PartnerGeneDisease IDDisease name# pubmedsSource